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Evaluation and Treatment MethodsAnn F. Corson, M.D.

September 29, 2018

Evaluation of chronic patients

• History– Risk factors for infectious diseases

• Travel history, vector and community exposure – Complete medical history

• Detailed history from conception to present– Maternal history

• Trauma history (physical and emotional)• Surgical history• Dental history• Manipulative procedures

September 29, 2018 Ann F. Corson, MD 2


• History– Social history

• Nutritional habits, smoking, alcohol, drugs• Mold risk factors in home, work, school, car,

places frequented for hobbies and entertainment• EMR sources in home, school, work environments • Pets, past and present

– Family history• Biological grandparents, parents, siblings, children• Family dynamics and nuclear family arrangements



• History– History of present illness

• When did they last feel well?– Review of systems

• Very detailed past and current ROS– Physical exam

• Vital signs, tongue, face, ears, eyes, nose, lymph nodes, thyroid, throat, chest, heart, abdomen, joints, soft tissues, skin, nails, cranial nerves, motor/sensory testing, reflexes, gait and balance, mental status, affect, behavior


Evaluation of chronic patients• Laboratory evaluation

– Infection labs• Igenex, Fry Labs, MDL, LabCorp, Galaxy

– Medical work up• CBC diff, Complete Metabolic Panel, Urinalysis• Hypercoagulability• Biotoxin illness • Autoimmunity • Hormones

– Methylations genetics• 23 & me, www.knowyourgenetics.com, Doctor’s Data


http://www.knowyourgenetics.com


• Laboratory evaluation

– Food and environmental allergy assessment

• Serum, salivary, stool IgA, IgE, IgG

• Lymphocyte stimulation

– Stool analysis

– Heavy metal testing

• Urine, stool, hair

– Methylation functional evaluation

– Specialty nutritional testing


Autoimmune work up

• Anticardiolipin antibodies – IgG, IgM, IgA • Antigliadin antibodies

– Serum, stool, saliva• Thyroid auto-antibodies

– TPO, thyroglobulin antibody, TSH receptor antibody• Antinuclear antibodies• Rheumatoid factor• Cyclic Citrullinated Peptide (CCP)• Myelin Basic Protein auto-antibodies


Hormone work up• Adrenal function

– ACTH, 24 hour salivary cortisol, DHEA• Thyroid function

– TSH, free T4, free T3, Reverse T3, autoimmune antibodies

• Gonadal function– Total and Free Testosterone, Dihydrotestosterone– Estrogen, Estradiol, Estrone– LH, FSH – Prolactin– Sex Hormone Binding Globulin (SHBG)


Referrals

• Mold inspection and remediation

• Cranial osteopathy

• Acupuncture

• Biological dentistry

• Alternative Lightwire Functionals orthodontistry

• Lymphatic drainage

• Neurological chiropractic

• Physical therapy

• Resolution of emotional issues


Treatment tools• Drainage and regulation medicines

– Homeopathic and herbal medicines• Clean and regulate organ function, clean matrix

– Immune-metabolic, immunobiologic medicines• Microbial derived homeopathics – restore regulatory

set points of metabolism, immune, hormone systems• Enzymes of all kinds

– Fibrinolytic– Proteolytic– Biofilm busting agents


Treatment tools• Allopathic antibiotics• Allopathic antiparasitics• Single and combination herbal antimicrobials• Binders

– Activated charcoal +/- herbs, bentonite clay– Microchitosan, humic acid, CSM, chlorella,

cilantro • Nutraceuticals

– Trace minerals, methylation nutrients, fats, phospholipids, mitochondrial support, MVIs


Treatment tools• Reduce systemic inflammation

– Nutraceuticals, herbs, homeopathics, allopathic meds

• Replete and optimize nutrition– Individualized supplementation

• Provoke to remove toxic foci, repair, revitalize– Spagyric homeopathics, herbals, nutraceuticals

• Meridian and energy medicine– Acupuncture, acupressure, electrodermal

screening, biofeedback machines


Treatment tools• Dietary modification

– Paleolithic dietary principles– Allergen avoidance

• Lifestyle modification– Clean air and water– Avoidance of disease vectors– Avoidance of mold and toxic chemicals– Avoidance and reduction of EMR sources– Graded exercise


Gut dysbiosis and repair

• Remove

– GMOs, glyphosate

– Food additives, chemicals, plastics

• No processed foods

– Mold toxins

– Metal toxins

– Provoking foods that up-regulate GALT

– Dysbiotic organisms and invasive pathogens

• Parasites, bacteria, fungi, yeast, etc…..


Gut dysbiosis and repair• Repair

– Gut mucosal lining – L-glutamine, aloe – Treat hypercoagulability – fibrinolytics – Down regulate GALT – immuno-metabolics– Address invading pathogens – antimicrobials– Digestive function – HCL, bile, enzymes– Elimination – effective peristalsis


Gut dysbiosis and repair• Restore

– Normalize micro biome – prebiotics, probiotics, fiber

– Redox potential at gut lining– Gastric acid production– Pancreatic exocrine function– Gallbladder function– Peristalsis and bowel elimination


Gut dysbiosis and repair• Revitalize

– GALT normalization• Immunomodulating medicines, spagyric

homeopathics– Nutrient absorption– Liver function

• Detoxification• Methylation• Metabolism, growth and repair• Hormonal regulation


Herxheimer reaction support• Results from:

– Toxin release, inflammatory cytokines and increased soluble fibrin production

• Buffer the download:– Enzymes – fibrinolytic, proteolytic– Drainage – organs, lymphatics, ECM– Binders – bile acid chelation– Nutraceuticals

• Optimize methylation, essential fatty acids and phospholipids, trace minerals, and multivitamins

• AlkalizationSeptember 29, 2018 Ann F. Corson, MD 18

Commonly overlooked issues

• Most commonly overlooked issues:

– Biotoxin illness – chronic mold exposure

– Hypercoagulability – excess soluble fibrin

– Glyphosate poisoning / dietary noncompliance

– Unrecognized infections

• Protomyxzoa / Funneliformis biofilms

• Occult dental infections – especially root canals

– Heavy metal toxicity/vaccine injury

– Mast cell activation

– Structural issues

– Genetic methylation faults


Biotoxin illness work up• HLA typing – DRB1, DQB1, DRB3-5• Transforming Growth Factor β-1 (TGF β-1)• Matrix Metallopeptidase 9 (MMP-9)• C4a and C3a• Urinary mycotoxins• Vascular Endothelial Growth Factor (VEGF)• Antidiuretic Hormone (ADH) and osmolality• Vasoactive Intestinal Peptide (VIP)• Melanocyte Stimulating Hormone (MSH)• Leptin


Biotoxin/mold illness treatment

• Remove patient from ongoing toxin exposure• Reduce inflammatory cytokines• Remove biological toxins from body

– Bind bile – Sweat

• Nutritional support– Glutathione– Individualized nutraceuticals

• Remove patient from ongoing exposure


• Fibrinogen• Antithrombin Activity III • D-Dimer• Protein C Activity• Protein S Activity• Activated Protein C

Resistance• Factor II Activity• Alpha-2 Antiplasmin

• Plasminogen ActivaseInhibitor -1 (PAI-1)

• Lipoprotein a• Homocysteine (cardio)• Lipid panel• Prothrombin Fragment 1+2• Thrombin – Antithrombin

Complexes (TATs)


Hypercoagulability work up

Hypercoagulability treatment

• Treat with:– Fibrinolytic enzymes– Proteolytic enzymes– Other enzyme combinations– Heparin

• IV or SQ– Homeopathic immune modulators– Herbs


Hypercoagulability treatment

• Caveats:– Exposure to heavy metals, mold and environmental

toxins can significantly flare hypercoagulability– Movement of heavy metals, mold toxins and many

environmental chemicals can exponentially worsen symptoms of hypercoagulability

– Herxheimer reactions result from both increased cytokines and soluble fibrin production and almost always require an increase in enzymes

– Dissolving fibrotic debris in the body can release damaging toxins and infections


Protection from glyphosate• Eat 100% organic food

– Glyphosate found in organic food• Eat sauerkraut and apple cider vinegar

– Contain acetobacter – one of the very few microbes that can metabolize glyphosate (acetobacter are bacteria that make vinegar or acetic acid from sugars and ethanol)

• Avoid supplements in gelatin capsules• Avoid drugs derived from animal products

– Desiccated thyroid, HRT, calcium, lanolin, anticoagulants, procoagulants, insulin, digestive enzymes (pepsin, trypsin and lipase), plasma expanders, dermatological preparations, antineoplastic agents, lanolin, heme iron, gummy vitamins

• Avoid vaccines, especially MMR September 29, 2018 Ann F. Corson, MD 26

Protection from glyphosate

• Sunlight exposure without sunglasses or sunscreens

– Make cholesterol sulfate in skin

• Eat high sulfur foods

– Cruciferous vegetables, fresh ginger, garlic, coriander,

turmeric

– MSM, Epsom salt baths

• If sensitive to sulfur, fix gut dysbiosis, then supplement

• Trace mineral supplementation, use sea salt

• Chelation with charcoal, humic acid, fulvic acid, herbs

• HBOT

• Grounding to remove EMR


Heavy metal toxin treatment• Remove and reduce metals/toxins exposure

– Amalgams, vaccines, dietary sources• Chelation

– Traditional chelation agents– Nutritional support of metal detoxification– Correction of methylation defects– Binders for elimination in stool

• Kidney and liver support– Solidago, glutathione

• Lymphatic drainage– Lymph Star Pro


Structural issues

• Laboratory evaluation– Total serum tryptase– Plasma histamine +/- heparin– Urinary N-methyl histamine– Urinary PG D2– Leukotriene E4– Chromogranin A

• Physical examination– Abdominal skin capillary refill and histaminic weal

September 29, 2018

Mast cell activation work up

Ann F. Corson, MD 29

Structural issues

• Anti-histamines– H-1 blockers

• Loratadine• Ketotifen (compound orally) 0.5mg

– H-2 blockers• Famotidine

• Mast cell stabilizers– Cromolyn sodium

• Leukotriene inhibitors– Montelukast

September 29, 2018

Mast cell activation treatment


Structural issues

• Herbals

– �� - stinging nettle and 9 other herbs

– NeuroProtek �� - quercetin, rutin

– Allqlear - quail egg ovomucoids act as tryptase

inhibitor which stabilizes mast cells

• Nutrients

– DAO enzymes - break down ingested histamine

– Bromelain

– Vitamin C

• Low histamine diet

September 29, 2018

Mast cell activation treatment


Patient responsibilities

• Get OUT of MOLD…..!!!!!• Follow treatment protocols as prescribed• Comply with dietary recommendations

– Paleolithic oligoantigenic principles– No GMO, no processed food– No HFCS, limit sugar to fresh fruit, no dried fruit– Avoid all gluten and limit most grains– Often need to avoid all dairy products


Patient responsibilities

• Life style modifications– Avoid blood sucking insects

• Ticks, fleas, flies, mosquitos– Avoid toxin in food, home, work, school, car

• Chemicals are everywhere in air and water– Household cleaners, personal care products including

toothpastes, soaps, shampoos, hair dyes, nail polish, lotions, cosmetics

• No smoking, no drinking alcohol

• See referral professionals as requested


Spirituality and FaithIt is healthy to respect and revere the Divine

Truthfulness, Compassion and Forbearance is good

Zhen Shan Ren Hao FalunDafa.org


Case history

• History of present illness: 38 year old female veterinarian with fatigue, brain fog and pain.– No anaphylactic allergies, but many drug

sensitivities– Three years prior, developed hand dysesthesias

and body pain that prevented her performing surgery. She was diagnosed with Bb and treated with 30 days of oral doxycycline. Her nerve pain went away and she was able to work again.


Case history

• History of present illness: 38 year old female veterinarian with fatigue, brain fog and pain:– Four months after doxycycline, she had such a

rapid return of severe fatigue, brain fog, and body pain that she was bedbound within a month.

– Treated by LLMD with triple antibiotics (Biaxin helped best) which got her out of bed with 70% less pain, but she became yeasty, developed leaky gut, had Crohn’s reactivation, mast cell activation, reactive hypoglycemia and adrenal fatigue.


Case history

• History of present illness: 38 year old female veterinarian with fatigue, brain fog and pain:– Treatment for Bb coincided with moving into a new

clinic building at work that is moldy.• 90% employees had new physical or psychological

complaints.– She has not been able to work for 18 months.– She also feels better out of her own house.


Case history

• Past medical history notable for:– Second child, healthy mom with metal amalgams,

breast fed, chicken pox, measles, mumps, strep– Full immunizations, some flu shots– ENT infections as child - treated with “lots of abx”– Mononucleosis age 15– Campylobacter age 17– Quincy requiring tonsillectomy age 18– “Scarlet fever” age 27


Case history

• Past medical history notable for:– Crohn’s disease age 30– Hepatitis – unknown etiology age 31

• Exposure to exotic animals during training

• Past traumatic history notable for:– Falls off horses – childhood– Age 19 - MVA: back seat, no seat belt, roll over,

bad whiplash, no LOC– Kicked by horses, cows, bitten by feral cats


Case history

• Family history:– Mother a “worrywart” with possible Hg toxicity

• MM – pancreatic CA• MF – lung CA/atherosclerosis

– Father with bladder CA• FM – alive and well at 90 years old• FF – CVA

– Brother – skin disease– No children


Case history

• Social history:

– Became veterinarian in 2000

– Non-smoker, social drinker - ETOH intolerant now

– Married for second time recently, step children

• Mold exposure:

– Lived in one damp house in 2003 - not sure if

current house is dry

– Current work place moldy


Case history

• Vector Borne Disease risk:– Grew up camping in forested tick endemic area– Extensive travel to Europe, Thailand, New Zealand,

Australia, South Africa, USA (MD) were she hiked and camped

– Sustaining many insect bites• Has had malarial prophylaxis

– No known tick bites– Currently has dogs


Case history

• Recently diagnosed with:

– Low ferritin

– Reactive hypoglycemia

– Mast cell activation syndrome

– Lyme disease

• PCR positive Bb

• Sero-positive Bb (two labs)

• Decompensated and became disabled:

– 6 months after her office moved into a new building


Case history

• ROS at first office visit:– Horrible sleep with nightmares and sleep paralysis– Anxiety, mood swings– Increased startle response, sensory hypersensitivity– Inability to tolerate aerobic exercise– Fatigue, poor stamina– Cognitive dysfunction, headache– Heavy menses– Joint and muscle pain


Case history

• On examination:– Unable to tolerate lights on in office during exam– Slim body habitus, normal VS, temp 97.8– Pale tongue, central crack, thin tan coat, scalloped

edges, some distention of SL veins– Shoddy cervical lymph nodes– Sore cervico-thoracic junction muscles– Diffusely tender abdomen, doughy consistency on

palpation, poor capillary refill


Case history

• On examination:– Cool hands with poor cap refill– Legs cold from feet to mid thigh, dependent rubor– Clear mentation with fluent speech– Light sensitive– Slow uptake of Achilles ankle jerk

• Impressions/differential diagnosis???


Case history

• Initial treatment:– Parsley, Itires, Sparga– Boluoke– Bar-2, Olive Leaf Supreme– Activated charcoal, Microchitosan– SyInfect lotion– Nutritional supplementation - added molybdenum

• Continued probiotics, digestive enzymes, Vit D3, adrenal support, EFAs, magnesium

• Stopped curcumin, iodineSeptember 29, 2018 Ann F. Corson, MD 47

Case history

• Laboratory work up revealed:– HLA 15-6-51, 7-2-53A– Ochratoxin A 2.68, Tricothecenes 0.13– Actomyosin IgA 25.25– TATs 8.0, Prothrombin fragments 1&2 7.3, protein S

74, protein C 110, Anti-thrombin 106, D-dimer 2.0, lipoprotein a 133

– MMP-9 676, C4a 1163, C3a 265, TGFb-1 6040– Few biofilms, punched out RBCs, no coccobaccilli


Case history

• Laboratory work up revealed:– Q fever IgG IFA 1:128– Bb WB

• IgM +18, 23-25, 39; IND 83-93• IgG +31; IND 34,39

– Rickettsia IgG 1:40 (Spotted and Typhus)– EBV

• VCA IgG 7.50, EBNA IgG 6.33, EA IgM 1.28 IgG 2.08– HHV-6 IgG 7.0– Mycoplasma pneumonia IgG 2.58


Case history

• 6 weeks later patient reported:– Better energy and brain function– Neck not stiff – No nausea– Less heavy and less painful menses– No morning stiffness– Less cold hands and feet– Can actually feel a bit refreshed in the morning

upon awakening


Case history

• Treatment at 6 weeks:

– Increased Boluoke and drainage

– Added oil of oregano

• At 10 weeks patient reported:

– Cognition better

– Energy MUCH better

– More joint/bone/nerve/muscle pain

– Ammonia smell to body


Case history

• Treatment at 10 weeks:

– Increased Boluoke

– Increased Parsley and Itires

– Increased Bar-2

– Increased molybdenum

– Added L-MTHF


Case history

• Laboratory work up revealed:– Homozygous: COMT V158M, COMT H62H,

MTHFS, MTRR A66G, SHMT-2, VDR Bm– Heterozygous: CBS C699T, CBS A360A, MTRR

A664A, MTHFR C677T, MAO-A R297R, BHMT-08


Case history

• Evaluation at 18 weeks into treatment:– Getting better in many ways: psychiatrically, overall

cognition, less pain, less neurological symptoms, bladder better, joints better…

– Crohn’s symptoms had flared horribly – unable to eat, bleeding…


Case history

• Treatment at 18 weeks:– Added Lymph-Tone III, apo-stom, phosphatidyl

serine– Continued Boluoke, Bar-2, SyInfect, probiotics, gut

repair nutrients

– Increased hydroxy B12, lowered folate

– Stopped Sparga, Microchitosan, oil of oregano, activated charcoal

– Asked patient to send weekly updates


Case history

• At nearly 21 weeks treatment:– The weekly update brought “good news”, more

formed stools, no blood, small amount mucus, only minimal left sided abdominal pain – added extra gut healing visualization to her daily meditation

– New energy, clarity of thought, feeling “like my old self”, able to walk dog, had friends for dinner for first time in three years, even went to a salsa class


Case history

• Evaluation at 24 weeks into treatment:– “Much better”, better energy, stamina, libido,

cognitive function, more clearheaded, brain “so much better”, less noise and odor sensitive, no constipation, no abdominal pain, only passed a little blood/mucus with stool last month, none this month.

– Terrible sugar cravings, some palpitations after eating sugar and some coccyx pain

– Labs showed no autoimmune thyroid, ANA 1:40– GI doc will be repeating colonoscopy soon


Case history

• Treatment at 24 weeks:– Lowered drainage to BID– Continued Boluoke 3 caps TID– Increased Bar-2 to 20 drops BID (over 2 wks) – Adjusted methylation supplements slightly– Added liposomal artemisinin 2 BID one day/week– For sugar cravings: MCT 60%/coconut oil 40%

2 teaspoons every two hours while awake.


Case history

• Evaluation at 33 weeks:– Patient continues to improve in cognitive function,

less HA, no sensory hypersensitivity, but still with some afternoon fatigue, insomnia, nocturia, thirst, aerobic exercise tolerance causing significant drop in body T�

– Stress due to mother’s sudden myocardial infarction• Laboratory evaluation:

– Salivary adrenal stress prolife all within normal range


Case history

• Treatment changes at 33 weeks:– Stopped Bar-2 and omega 3– Added Toxease-GL, olive leaf extract, omega 3,6,9– Increased artemisinin 2 BID to 2 days in a row/week– ¼ tab Phenergan for sleep– Continue drainage, enzymes and other nutritional

support at same doses


Case history

• Correspondence at 36 weeks:– Shortly after increasing artemisinin she had

myalgias, deep bone pain in hands, dysesthesias, heart palpitations, rapid “flip chart” images in brain, neck weakness and burning pain as if vertebrae moved, nausea and loose stools. Improved 80% after about 10 days

• Treatment adjustment:– Add ARG Nattokinase 100 mg soft gels 2 TID– Continue rest of protocol as before


Case history

• Evaluation at 41 weeks:– Patient was more symptomatic with less good days.

Ongoing herx to artemisinin, more fatigue, brain fog, waking up with horrible palpitations and brain-racing OCD, stiff neck, increased sensory hypersensitivity, limbs going to sleep easily, poor sleep quality, although less temperature drop with exercise

– Had horse fly bite with significant histamine reaction as well as a spider bite


Case history

• Treatment changes at 41 weeks:– Add Boluoke 3 TID to nattokinase 100 mg 2 TID– Add IMN-V III 5 drops daily– Add Smilax Supreme 2 BID– Add Trace Minerals– Add Microchitosan (ARG) 2 at bedtime– Increase molybdenum and phosphatidyl serine– Stop apo-Stom and Toxease GL


Case history

• Treatment changes at 41 weeks:

– Continue B12, olive leaf extract, Parsley, Lymph-

Tone IIII, digestive enzymes, omega 3.6.9,

probiotics, MVI

– Don’t take artemisinin until above protocol on board

completely for at least 7 days


Case history

• Correspondence at 44 weeks: – Patient had a camping holiday in France away from

EMFs, in warm weather, with good friends– Off artemisinin, she had better energy, no pain, no

brain confusion and less dysesthesias– Home again, she felt more fatigued with ulnar

dysesthesias waking her from sleep• Plan:

– Hold artemisinin until we discuss at office visit


Case history

• Office visit evaluation at 49 weeks: – Patient had less neurological symptoms, more

energy but complained of ongoing insomnia, fatigue, poor mental and physical stamina

– Husband came home one day with badly mold contaminated clothes one day that made her feel worse

– Intermittent sudden tooth pain and receding gums– Palpitations eased off artemisinin


Case history

• Office visit evaluation at 49 weeks: – Bowels still ‘really good!’, no mucus or bleeding, still

requires digestive enzymes to control bloating– Much less muscle pain– Sleep very problematic still– ‘Body’ anxiety comes in waves in am, emotionality,

irritability, some anger– Poor aerobic exercise tolerance, tried to water ski

but ‘ran out of mitochondrial energy’


Case history

• Office visit examination at 49 weeks:

– Up 15 pounds with more normal body habitus

– Tolerating lights on in exam room

– Stable vital signs with normal T�

– Very sore SI joints

– Very cold feet with poor capillary refill, hands only

slightly better

– Overall ‘edgy’, slightly agitated affect, depressed

reflexes


Case history

• Treatment changes at 49 weeks:– Stop Parsley, nattokinase, IMN-V III, Smilax, OLE– Add Citriplus 20 drops BID– Add Toxex 5 drops QD– Add Bb-2 20 drops BID– Add Hemoguard Supreme 2 caps BID for 3 months– Restart artemisinin 2 BID at only one day a week– Lower Boluoke to 2 caps BID– Continue L-T III and other nutrients as before


Case history

• Two days after 49 week office visit:– Patient developed sudden severe deep

perineal/rectal pain (an old symptom that had been gone) followed by diarrhea, mucus and some blood in stool, cleared over several days

– She admitted dietary indiscretions and increased activity level around time of visit

• Plan:– Add Dan Shen Supreme 1 BID to protocol


Case history

• Laboratory evaluation from 49 week visit:– Fry lab Q fever IgG 1:512 (up from 1:128)– Real Time Lab urinary mycotoxins all negative– Cyrex IgA Actomysosin IgA 25.57 (had been 25.25),

Occludin/Zonulin IgM 2.90 and Lipopolysaccharides IgM 2.22 (both new elevations)


Case history

• Correspondence at 51 weeks:– Patient referred to ID specialist regarding increased

Q fever antibodies– Add Bar-2 10 drops BID– Add BLt 5 drops BID


Case history

• Evaluation at 65 weeks:– Patient being followed (but not treated) by GP and

neuro-cardiologist for Q fever, ECHO pending, EKG showed RtBBB

– Visible mold found in attic due to roof leak– Overall better: much less palpitations, less fatigue,

can walk 2 miles with SOB, doing 30 minutes yoga twice a week, starting swimming, less cold hands and feet, can eat a lot of foods that used to bother her


Case history

• Evaluation at 65 weeks:– Still complains of needing medication to sleep,

anxiety, mood swings, irritability, palpitation flare and headache with artemisinin, still gets ‘paybacks’ if she pushes too much

– Despite all this she prepared and gave a lecture to over 50 vets about Lyme disease!


Case history

• Treatment changes at 65 weeks:– Stop artemisinin, Hemoguard, Lymph-Tone III,

Boluoke, molybdenum– Increase Dan Shen to 2 BID– Increase Bar-2 to 20 drops BID– Add Vit E 400 IU daily– All the rest the same


Case history

• Evaluation at 80 weeks:– Continues to improve in energy, overall functioning,

starting to run and tolerating it– Psychologically “so much more myself”– Handling the high sensory input in social settings

much better– Still has several days with fatigue, achiness, low

strength that starts day 4 of menses and lasts about one week

– InsomniaSeptember 29, 2018 Ann F. Corson, MD 76

Case history

• Treatment changes at 80 weeks:– Increase BLt to 20 gtts BID over three weeks– Add Tulsi Supreme, start with ½ cap QD in am and

work up to 1 cap BID over about one month– Somculpin 10 gtts q hs +/- Valerian root– Replace Vit D3 with Vit d3/K2– Stop Citri-plus, Toxex, phos. serine, Molybdenum,

Bar-2 and use up Dan Shen– Continue omega 3/6/9, Vit B12, MVI and digestive

enzymesSeptember 29, 2018 Ann F. Corson, MD 77

Case history

• Evaluation at 90 weeks:– Developed iritis after doing attic mold remediation

herself with respirator but no goggles– Two ticks bites – no rashes; three on dogs– Doing Dynamic Neural Retraining – helps!– Sent kayaking on day three of menses!– Trying to work one week in a vet practice– “I’m like a normal person”


Case history

• Treatment changes at 90 weeks:– Increase BLt ro 30 gtts BID– Restart Bar-2 10 gtts BID– Doxycycline 200 mg BID for 14 days– Nattokinase 100mg softgels 2 BID– All the rest the same


Case history

• Evaluation at 103 weeks:

– Bad spell after doxy for tick bite

– Horse fly bite with RM rash

– Weekend away at friends’ place with lots chemicals

– All resulted in: brain fog, dysesthesias, abdominal

pain, cracking of fingertips and separation of nail

beds, hair loss, fatigue, low mood, gut ‘crashed’


Case history

• Treatment changes at 103 weeks:– Stop Microchitosan, Tulsi, BLt– Nattokinase 100mg 2 BID– Serrapeptase 2 BID– Bb-2 10 gtts BID– Vital Guard Supreme 2 BID– Body Bio PC 1 tsp BID– Trace minerals, Mg++ up to TID– Melatonin 5mg when sun sets– Activated charcoal 2 q hs or 2 hr after dinner


Case history

• Update at 109 weeks:– Much improved sleep– Energy improving, though slowly– Much less anxiety, very little muscle twitching, hair

loss stopped– Gut better

• Plan: continue current protocol


Case history

• Evaluation at 119 weeks:– Gut has been fine– Felt better until running out of nattokinase and

serrapeptase– A little down


Case history


– Decrease serrapeptase and nattokinase to 1 BID

– Add Toxease GL 1- gtts BID

– Bar-2 10 gtts BID

– Vital Guard 2 BID

– Add Smilax 1 daily

– Continue: omegas, Vit E, Vit D3/K2, PC, B12,

Mg++, Core Minerals, Activated charcoal


Case history

• Follow-up at 130 weeks:– Patient had started HBOT and started herx’ing

badly after 12th HBOT dive with:• Loss of appetite• Terrific mood swings• Fatigue• Brain is ‘offline’• Poor sleep, wakes after a few hours with numb fingers or

arms, crazy dreams• Menses late


Case history


– Increase nattokinase to 2 caps TID

– Add Parsley 10 gtts to Bar-2 10 gtts BID

– Vital Guard 2 BID

– Add BLt 1- gtts increasing to 20 gtts BID over few

months

– Activated charcoal 1 q hs

– Continue HBOT


Case history

• Evaluation at 154 weeks:– Forgot to take Bar-2– Steady nose-dive after spending the weekend on

friends’ boat that was moldy during week 141• Fatigue• Brain fog• Poor sleep• Muscle twitches• Anxiety


Case history

• Treatment changes at 154 weeks:– Decrease BLt to 10 gtts BID– Stop nattokinase and replace with Boluoke 1 BID– Serrapeptase 1 BID– Parsley 10 gtts BID– Flex Now 2 TID– Bentonite clay ½ tsp q hs– Body Guard Supreme 2 BID pc– Transfer Factor Enviro 2 QD– All rest same


Case history

• Evaluation at 165 weeks:– Forgot to take Bodyguard twice daily– Improved but flared after busy weekend, physical

work and socializing, ? mold hit• Gut pain, nausea, poor appetite• HA, emotionality• Fatigue• Brain fog, ‘brain on fire’

– Increasing parsley and Boluoke as instructed helped a bit; exercise tolerance bit better


Case history

• Treatment changes at 165 weeks:– Increase bentonite clay ½ tsp BID for 2 weeks then

daily– Decrease Flex Now to 1 QD– Try to increase BLt to 15 gtts BID when able– Increase Vit D/K2 to 5000IU QD– Wild Green Supreme 1 scoop QD– Finish out TF Enviro


Case history

• Follow up at 171 weeks:

– Feeling great last 7 weeks but dog just died


– Slowly increase BLt to 20 gtts BID

– All the rest the same


Case history

• Last contact at 173 weeks (Feb. 28, 2018)– Doing better

– Eating more variety foods with better appetite– Energy better

• To be continued…… ???


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