EXTRACELLULAR MATRIXASWINI.A

Reg No:115011305004

2nd M.Tech(nanotechnology)-integrated

THERE ARE TWO TYPES OF EXTRACELLULAR MATRIX

Animal extracellular

matrix

1Plant

extracellular matrix

2Extracellular

matrix

3

PROCESSES

FIXTURE

Mechanism,cellsDEGRADATION

Degtadation substance,mechanism

MECHANICAL PROPERTIES OF THE EXTRACELLULAR MATRIX

1 Stiffnes and elasticity

gene expression2

4 differentiation

5 Durotaxis

FUNCTION OF EXTRACELLULAR MATRIX

Varying degree

Stiffness and

elasticity

Soft brain tissue to

hard bone tissue

Changes one cell type to another

Cell migration

Attracts positively

Translocated cell

Using regrowth Works with

stem cells

Regrow all parts of human body

FOUR MECHANICAL PROPERTIES OF EXTRACELLULAR MATRIX

Elasticity and stiffness1

Gene expression on effect2

Durotaxis3

EXTRACELLULAR MATRIX GENE EXPRESSION

• Varying degree stiffness and elasticity,form soft brain tissue to hard bone tissue.

• The extracellular matrix effects on both cell behavior and gene expression.

• Matrix elasticity can direct cellular differention,the cell changes from one cell type to another.

Non-proteoglycans2

proteoglycans1

THEY ARE TWO MOLECULAR COMPONENTS ARE THERE

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