from cell line development to membrane protein production
TRANSCRIPT
From Cell Line Development to Membrane Protein Production
Membrane proteins are proteins that interact with biological membranes. They are targets of over 50% of all modern medicinal drugs. It is estimated that
20–30% of all genes in most genomes encode membrane proteins.
Prepared and Compiled by Creative Biomart
Importance
• Membrane receptor proteins relay signals between the cell's internal and external environments.
• Transport proteins move molecules and ions across the membrane. They can be categorized according to the Transporter Classification database.
• Membrane enzymes may have many activities, such as oxidoreductase, transferase or hydrolase.
• Cell adhesion molecules allow cells to identify each other and interact. For example proteins involved in immune response.
However
• Despite their importance, membrane receptors are notoriously difficult to prepare in pure, correctly-folded form in sufficient quantity for drug discovery purposes.
Membrane Protein Services
• Creative Biomart has been working with pharmaceutical, biotechnology, and academic customers and collaborators since its founding, providing membrane protein-related products and services that advance its customers’ scientific objectives.
• • Custom Membrane Protein Production• • Cell Line Development and Membrane Prepar
ation• • Lipid-based Protein Immobilization
More Details
• Creative Biomart• http://www.creativebiomart.net/Membrane-Protein
-Services.htm
• 45-16 Ramsey Road, Shirley, NY 11967, USATEL: 1-631-559-9269 EMAIL: [email protected]
• St John's Innovation Centre, Cowley Road, Cambridge CB4 0WS, UK TEL: 44-207-048-3343