A cost-effective strategy for marker assisted selection (MAS) in apple (M. pumila Mill.): The experience from the Fondazione Edmund Mach

programme for resistance and quality traits

Riccardo Velasco

AgricolturaMigliore output con minore input Fondazione Edmund Mach

AlimentazioneDept. Of Genomics and Biology of Fruit Crops

Center of Research & InnovationCenter of Research & Innovation

FEM Research and Innovation FEM Research and Innovation CentreCentreHuman ResourcesHuman Resources

290 collaborators 44% PhD holders79 PhD students21% foreign

nationalityAverage age 36

y.o.

Center of Research & InnovationCenter of Research & Innovation

Genomics and Biology of Fruit CropsBetter output with less outputs DEPARTMENT 1

Gene Function Grapevine Applied Genomics Rosaceae Applied Genomics Structural Genomics | Functional Genomics PLATFORM TECHNOLOGIES (Rosaceae Breeding – Grapevine Breeding -

Sequencing and Genotyping – Plant Transformation and tissue culture)

Germplasm platform

Apple:- 13.4 ha for apple breeding + germplasm collection- 1,200 accessions (wild and cultivated spp.)- 54,000 genotypes under evaluation /several mapping population (quality and pyramidation of resistances)-8,000 genotypes in greenhouse

Grape: - 4.5 ha for grapevine breeding + germplasm collection

- 1,900 accessions (wild, hybrids and cultivated)- 12,000 new crosses (crosses, selected individuals or large mapping populations) resistances with high quality standards

Softfruits: - 2.5 ha for raspberry & blueberry breeding + germplasm - 104 strawbeery accessions - 140 blueberry accessions (20,000 seedlings/48 crosses) - 240 raspberry accessions (14,300 seedlings/110 crosses)

Genomics and Biology of Fruit CropsCenter of Research & InnovationCenter of Research & Innovation

Five genomes sequenced…

From DNA sequence…

...to mapping the genomic determinants of phenotypes…

…to the use of biodiversity to have new opportunities...

…to know the genetic bases of biodiversity...

Applied Genomics

Genomics-enhanced gene mappingFire Blight (Erwinia amylovora)

Apple scab (Venturia inequalis) Vg, Vm and Vb loci

Positional cloning of the Columnar (Co) locus

Apple proliferation (Candidatus Phytoplasma mali)

Genetic bases of self-thinning

MDP00004781530,8MDP0000301846 MDP00002593166,9MDP00007117747,9MDP00006835358,8MDP0000633218 MDP000040114011,2MDP000015271815,7MDP0000159587 MDP000057204715,8MDP000002565016,2MDP000031227418,4MDP000058001018,5MDP0000188907 MDP0000288901 MDP000018994118,6MDP0000712620 MDP0000191048 MDP000081053918,7MDP000071262318,8MDP0000527355 MDP0000701985 MDP0000268507MDP0000893993 MDP0000893994 MDP000021854918,9

MDP000030167719,5MDP000025779719,6MDP000094008620,7MDP000012477022,3MDP000013646623,1MDP000072349724,3MDP0000321745 MDP000025195624,4MDP0000262827 MDP000013074824,8MDP000060213925,0MDP0000288378 MDP000075625425,2MDP0000122747 MDP0000197219 MDP000089085426,3MDP0000233483 MDP000019370026,8MDP000014670326,9MDP0000237202 MDP0000128157 MDP000072757027,0MDP000045518027,1MDP0000933900 MDP000089703627,7MDP000029468228,0MDP0000406270 MDP000028073028,2MDP000067121028,7MDP000030882728,8MDP000032104930,4MDP000016879030,5MDP0000151262 MDP000061266030,9MDP0000121609 MDP0000761338 MDP000013959231,0MDP0000705786 MDP0000882983 MDP000027282331,4MDP000083629331,5MDP000013665231,6MDP0000392668 MDP0000688878 MDP0000291838MDP0000138340 MDP0000200646 MDP000027919731,7

MDP000044082931,8MDP0000204944 MDP000030027131,9MDP0000151717 MDP000070324432,0MDP0000151095 MDP000025963333,3MDP000031287433,7MDP000023022833,8MDP000031907233,9MDP000066882834,2MDP0000151159 MDP000021746534,5MDP000025848234,6MDP0000250651 MDP000013908334,7MDP000023949635,5MDP000023464135,7MDP000014641535,8MDP000023621036,1MDP000028595536,5MDP000025962037,6MDP000013665439,7MDP0000274127 MDP0000198407 MDP000068295340,0MDP0000252300 MDP000057361741,1MDP000015773741,4MDP000031970041,9MDP000012805842,2MDP000091749642,3MDP000013962842,4MDP000019579844,7MDP000011918444,8MDP000031012845,2MDP000025564246,5MDP000070524446,6MDP000005563947,3MDP000013367147,7MDP000014416749,9MDP000017000550,0MDP000027944650,1MDP000037736451,3MDP000013236052,1MDP000062156952,5MDP000022537652,8MDP0000446783 MDP000014700953,4MDP000016572954,1MDP0000772420 MDP000043169654,5MDP0000265383 MDP000027973355,8MDP000032275556,2MDP0000249604 MDP000087072756,4MDP000025630656,5MDP000046221456,9MDP000017612357,1MDP0000919323 MDP000061411558,0MDP0000320566 MDP000014636058,3MDP0000229827 MDP0000299112 MDP0000157124MDP0000299114 MDP0000226941 MDP0000536969MDP0000131899 MDP0000254030 MDP0000306013

58,4

MDP0000854241 MDP000085424258,5MDP000050324658,6MDP000050324858,7MDP000023894259,0MDP000013333459,1MDP000050806859,3MDP000040885359,4MDP000030055659,5MDP000068460559,8MDP000024625860,5MDP0000296814 MDP000086661160,6MDP000024898160,8MDP0000144597 MDP0000462145 MDP000024959261,2MDP000020027261,3MDP0000262710 MDP000015522661,7MDP000012565862,1MDP000015644062,8MDP000021389262,9MDP000021707363,9MDP0000127054 MDP000029764664,4MDP000022607464,8MDP000068916264,9MDP000026334965,0MDP000019185165,1MDP000013617765,3MDP000029357866,5MDP0000863082 MDP000027781566,6MDP000047825266,7MDP000077157367,0MDP0000416305 MDP0000156509 MDP0000214162MDP000041630767,5

MDP0000165031 MDP0000178570 MDP0000656929MDP0000657536 MDP000065753767,6

MDP000029656769,1MDP0000318862 MDP000015512469,4MDP0000188700 MDP000020832269,5MDP0000219647 MDP0000191607 MDP000046839170,2MDP000085403970,3MDP0000242436 MDP0000277370 MDP0000128265MDP000029452671,0

MDP000027737171,1MDP000025423171,3

chr_1

MDP00003182161,2MDP00005024401,4MDP00006156842,8MDP00005248762,9MDP00001503823,0MDP00002648093,2MDP00003082243,6MDP00002934563,7MDP0000277672 MDP00001298603,8MDP00001658024,0MDP00005138804,3MDP00003264934,8MDP00002147144,9MDP0000185723 MDP00006377375,0MDP00002996585,3MDP0000644549 MDP0000321792 MDP00001649665,8MDP0000891962 MDP0000891965 MDP0000214625MDP0000201387 MDP00002760345,9MDP0000305297 MDP00001966276,0MDP0000288876 MDP0000306580 MDP00002151826,3MDP00003159596,4MDP00006963316,6MDP00001570356,9MDP0000136806 MDP00001656567,5MDP00002705737,6MDP00001720657,7MDP00004308707,8MDP00004519048,2MDP00001989768,4MDP000014519310,5MDP0000239167 MDP000025157910,7MDP000025102011,0MDP000037634711,1MDP0000123081 MDP0000219155 MDP0000438458MDP0000610753 MDP000066238711,2

MDP000014841411,3MDP000042071511,6MDP000018882712,0MDP000016910212,2MDP000017466412,3MDP000026406112,4MDP000024229712,6MDP000065241312,7MDP0000131126 MDP000022197712,8MDP000021250213,8MDP000072376214,0MDP000012450914,1MDP0000707034 MDP000060180014,3MDP000031098714,4MDP0000874578 MDP000040621714,5MDP000028621014,6MDP000041770415,6MDP000025289915,7MDP000018088215,8MDP0000452677 MDP000043564415,9MDP0000548003 MDP0000548004 MDP0000552242MDP000028855416,0

MDP0000200513 MDP0000156075 MDP0000277173MDP000021721916,1

MDP0000251898 MDP000021722016,2MDP000013336716,8MDP000031822917,2MDP000058531517,9MDP000021198718,0MDP0000704216 MDP000088663718,3MDP000051548918,4MDP000033758518,5MDP000013565219,3MDP000014451619,4MDP000016887119,5MDP000021605319,6MDP0000212766 MDP0000128793 MDP000053742520,0MDP0000692632 MDP000024847020,1MDP000019944221,7MDP0000292963 MDP000029296522,7MDP000027667623,0MDP000026331323,8MDP000013907324,2MDP000025048725,0MDP000058085825,2MDP0000232805 MDP000032794025,3MDP0000545023 MDP000018394125,4MDP0000181133 MDP000022538226,6MDP000087685826,8MDP0000224397 MDP0000710349 MDP000020722027,5MDP000012819027,6MDP000022339727,8MDP000012626728,4MDP000047092828,5MDP000086153529,2MDP0000380194 MDP000029806929,3MDP0000632145 MDP0000259172 MDP0000295032MDP0000198082 MDP000089451129,4

MDP000049418129,6MDP000070437729,7MDP000058529031,0MDP000030307832,4MDP000061067834,9MDP000029879335,0MDP000028343235,4MDP0000183156 MDP000015526735,5MDP000028658935,7MDP000015576835,9MDP000028427436,2MDP0000184294 MDP000031593836,3MDP0000160578 MDP0000215889 MDP000025280236,4MDP0000146806 MDP0000378862 MDP000056338536,5MDP0000172708 MDP000030686236,6MDP000067999336,8MDP0000249561 MDP000093244937,3MDP000026587537,8MDP000028123138,8MDP000023009239,8MDP000080147639,9MDP000091429740,1MDP000025133240,3MDP000081318640,5MDP000024494640,6MDP0000600192 MDP0000818140 MDP000025188340,7MDP0000135820 MDP000024814840,9MDP0000576390 MDP000066886941,0MDP000020379041,1MDP000022496945,6MDP000025422747,1MDP000068366047,5MDP000012462647,8MDP000084625747,9MDP000042019248,1MDP000021558748,4MDP000012567348,9MDP000012846349,2MDP000013732552,9MDP000018394853,0MDP000052394253,6MDP0000333317 MDP0000269483 MDP000066196054,4MDP0000801540 MDP000024753355,8MDP0000452189 MDP0000251256 MDP0000287234MDP000025250855,9

MDP000024940056,3MDP000032108856,7MDP000031476558,8MDP000014967658,9MDP000013694059,2MDP0000319630 MDP000023097261,9MDP000013916562,7MDP000063916764,0MDP000018903365,6MDP000016201967,2MDP000031661267,3MDP000051792468,1MDP000013933468,2MDP000023584169,0MDP000028152569,8MDP000075354769,9MDP0000412658 MDP000021155670,0MDP000031550070,4MDP000022529970,5MDP0000224062 MDP000019856171,6MDP0000204182 MDP000027498871,7MDP0000152045 MDP000023340771,8MDP0000180785 MDP000027067772,7MDP000024806373,2MDP000025528473,3MDP000089791973,4MDP0000136650 MDP0000156783 MDP000024938473,6MDP000064116774,0MDP0000893802 MDP0000852165 MDP000089870174,1MDP000030918174,4MDP000024900674,6MDP000092342675,9MDP000014595376,1MDP000066594578,0MDP0000300532 MDP000017493080,2MDP0000928314 MDP000015163881,0MDP000031208981,1MDP000029657683,7MDP000027321184,8MDP0000299506 MDP0000203952 MDP0000398467MDP0000422279 MDP000020283184,9

MDP0000129902 MDP000080352785,1MDP0000233590 MDP000042455385,4MDP0000170391 MDP000019868686,2MDP000023266587,3MDP000087088187,4MDP000093633188,7MDP0000274938 MDP000015329788,9MDP0000716997 MDP000018727989,0MDP000077695889,2MDP000043767689,7MDP000030597690,7MDP000012453690,8MDP0000196867 MDP0000173284 MDP000020408491,4MDP000028888691,9MDP000022972592,2MDP0000132456 MDP000018060592,4MDP000023253393,2MDP000072629593,5MDP000012387893,6MDP000022627995,0MDP000012677099,9MDP0000237091100,2MDP0000620349 MDP0000420893100,8MDP0000285057101,4

chr_2

MDP00002610670,6MDP00004880071,5MDP00005259332,3MDP00004330942,7MDP0000151924 MDP00001515112,8MDP00004309453,4MDP00002077224,2MDP00005804114,5MDP00001886985,6MDP00001299415,8MDP00004663316,4MDP00001350597,2MDP00002981668,0MDP00008257128,1MDP00001400468,3MDP0000119547 MDP00001370758,5MDP0000193347 MDP0000304484 MDP00002361389,1MDP000016134710,3MDP0000431358 MDP000064833810,4MDP000019050411,6MDP0000293847 MDP000048526811,7MDP0000166951 MDP000060284111,8MDP0000120157 MDP000012015811,9MDP000031783112,0MDP000022849412,1MDP000028478912,4MDP0000127732 MDP0000146449 MDP0000267678MDP0000921016 MDP000026768112,6

MDP0000514115 MDP000050780513,0MDP000031346013,5MDP000022211414,0MDP000030139914,1MDP000016402314,4MDP000018745414,5MDP000031360517,2MDP0000240081 MDP000016782417,4MDP000060101717,6MDP000029294917,7MDP000020289817,8MDP0000137531 MDP000069720619,6MDP000019411020,3MDP0000505274 MDP0000192448 MDP000015014020,5MDP000065269221,0MDP000032906321,5MDP000013528221,6MDP000082807722,1MDP000083012922,3MDP000015554322,4MDP000090415822,7MDP000011936423,2MDP000029671623,4MDP000027630723,8MDP0000499023 MDP000051615924,8MDP0000196802 MDP000026319225,7MDP000022132226,1MDP000013148126,2MDP000032012726,3MDP000031980627,1MDP0000148190 MDP000013485628,4MDP0000198741 MDP0000209964 MDP0000931131MDP000025698928,8MDP000028161330,1MDP000059529530,7MDP000075950431,9MDP000013079732,0MDP0000188581 MDP000023981032,7MDP000013363632,8MDP000026804533,6MDP000015538936,2MDP000013439736,5MDP000030443038,1MDP000014196139,5MDP000025770739,6MDP000015458940,0MDP0000187446 MDP000066328140,4MDP000025112541,9MDP0000265073 MDP0000132627 MDP000072998443,7MDP0000299944 MDP000020452543,8MDP000025450444,2MDP000094421044,5MDP000016653546,8MDP000016944247,4MDP000020247347,9MDP000002978348,4MDP000023425148,9MDP000080094549,2MDP000021700549,3MDP0000571255 MDP0000115697 MDP000013279449,5MDP000024742950,5MDP000031386352,2MDP000024633155,8MDP0000946614 MDP000012586255,9MDP0000146743 MDP000093688656,4MDP000022744256,6MDP000018034356,7MDP000019727158,8MDP0000744693 MDP000024311358,9MDP000028962659,0MDP000026327259,6MDP000018470459,9MDP000014411360,4MDP000031594761,1MDP0000179728 MDP0000212581 MDP0000593587MDP000032078962,2

MDP000075394663,2MDP000015383163,5MDP000020561763,9MDP0000132162 MDP000026207864,3MDP000029544064,9MDP000058190365,1MDP000015596565,4MDP000019676266,1MDP000086841966,9MDP000026203267,0MDP0000306058 MDP000012882768,0MDP000065140968,1MDP000032471869,4MDP000013586069,5MDP000013493670,0MDP000027339070,1MDP000057933270,2MDP000028156270,3MDP0000663949 MDP000079075070,4MDP000070860972,6MDP000020176973,6MDP0000273274 MDP0000481866 MDP0000273276MDP000024285474,0

MDP0000300393 MDP000021535174,6MDP000022204574,7MDP0000907178 MDP000017473474,8MDP000019793976,7MDP000014868076,8MDP0000270013 MDP0000264703 MDP000018462077,7MDP000029840877,8MDP0000289686 MDP000029106177,9MDP000030702078,1MDP000061707778,6MDP000012978779,0MDP000029579479,4MDP0000123466 MDP0000123668 MDP000013885380,1MDP000049841980,3MDP000044387680,4MDP0000247441 MDP0000202829 MDP000027425780,5MDP000056849881,6MDP000016252382,0MDP000025420382,1MDP0000196922 MDP0000294145 MDP0000200484MDP000079870582,4

MDP000079870782,5MDP000026624582,6MDP0000848905 MDP0000679280 MDP0000257135MDP000014779482,7

MDP000029448982,8MDP0000215772 MDP000031517683,0MDP000043768083,2MDP000025305583,8MDP000012452284,0

chr_3

MDP00002637560,3MDP00004163880,4MDP00002097051,0MDP00002621921,4MDP00005289841,8MDP00004305462,7MDP0000296410 MDP00001396092,8MDP00001337622,9MDP0000619501 MDP00005352473,0MDP0000258512 MDP00001933833,1MDP0000702868 MDP0000655939 MDP00001482213,2MDP00001564786,0MDP0000262916 MDP0000628479 MDP00006284846,3MDP00001892696,4MDP00005452746,6MDP00001658806,8MDP0000247372 MDP00005216628,1MDP0000228304 MDP00008280558,3MDP0000791464 MDP0000923579 MDP0000309801MDP00002408408,6

MDP00001495919,4MDP000029203111,0MDP000028730211,1MDP000015476412,2MDP000084900612,3MDP000049020014,1MDP000027771014,2MDP000025058414,4MDP000030238515,8MDP000044420516,1MDP000021193416,8MDP0000454482 MDP0000834641 MDP000083464217,0MDP000039876517,2MDP000026412417,6MDP000083465617,7MDP000031669418,0MDP000084372218,4MDP0000261492 MDP000019130420,2MDP0000291384 MDP000075039220,7MDP000020031921,9MDP0000256806 MDP000023154222,3MDP000080292423,6MDP0000444224 MDP000051009624,3MDP000025067225,5MDP0000201047 MDP000063544826,8MDP000016962127,2MDP000078858127,3MDP000031923528,3MDP0000310803 MDP000075242830,8MDP0000422442 MDP0000243428 MDP000079938730,9MDP000020784831,0MDP000041026431,5MDP000022200431,6MDP000021537131,9MDP000020809832,2MDP0000242087 MDP000080912532,3MDP000021590433,4MDP000090792934,4MDP0000135205 MDP000065045634,5MDP000012266534,7MDP000028457434,8MDP000017839834,9MDP000060354635,5MDP000063031935,6MDP0000456277 MDP000070670235,7MDP000075763638,2MDP000050394038,7MDP000043633840,6MDP000015386641,3MDP000021926941,5MDP0000708692 MDP000020809041,9MDP000089614042,7MDP000051832142,8MDP000027883943,1MDP0000256347 MDP000080030043,2MDP000062776543,4MDP0000627768 MDP0000858585 MDP000072931343,5MDP0000654033 MDP000003935743,6MDP000003935943,7MDP0000672345 MDP000019457043,9MDP000032183944,0MDP000029871144,4MDP000024541345,7MDP0000171707 MDP0000171708 MDP0000248589MDP000020535845,8

MDP0000212925 MDP000012929846,1MDP0000900024 MDP000085949246,6MDP000030027446,7MDP000012876146,8MDP0000179031 MDP000003217147,1MDP000085327447,3MDP000082884347,4MDP0000123025 MDP000052761547,6MDP000024227747,7MDP000013924847,9MDP0000734600 MDP000013667448,4MDP000026061749,2MDP000021941549,5MDP0000264666 MDP000023684749,6MDP0000923670 MDP000042354449,7MDP000031239749,8MDP000029733149,9MDP000005693550,2MDP000026717850,5MDP0000756894 MDP000020269052,5MDP000030809552,9MDP000014791353,0MDP0000363509 MDP000029558953,4MDP0000295593 MDP000019221053,5MDP0000782085 MDP000015498553,6MDP000023199353,7MDP0000265206 MDP000016834554,3MDP000032227954,4MDP0000692845 MDP000052947155,9MDP000029454356,1MDP0000194938 MDP000027896656,2MDP000037918656,5MDP000030191356,6MDP0000144203 MDP0000200038 MDP000019832756,7MDP000032140956,8MDP0000312169 MDP000058026356,9MDP0000287973 MDP000012531757,0MDP0000422558 MDP000030744257,5MDP000015187757,6

chr_4

MDP0000250856 MDP00002324170,8MDP00002332881,0MDP00008953411,1MDP00000889531,3MDP00009246121,5MDP00001950131,9MDP0000864349 MDP00007893902,1MDP00003067672,6MDP00002007373,1MDP0000202902 MDP00002058923,8MDP00003016663,9MDP00003706115,1MDP0000182058 MDP0000165000 MDP00003094515,2MDP00003019997,0MDP00002857807,1MDP0000243196 MDP0000320264 MDP0000174748MDP00003232917,2

MDP0000295452 MDP00001835407,9MDP00003167058,5MDP00007915539,0MDP00002556969,2MDP00001459919,8MDP0000173636 MDP00001736379,9MDP000080826210,5MDP0000569022 MDP000022415011,4MDP0000864970 MDP0000472095 MDP0000666752MDP000031395611,5

MDP000066720112,0MDP0000276278 MDP000017315112,3MDP0000729320 MDP000072932112,5MDP0000805422 MDP000018095012,6MDP0000256492 MDP0000251135 MDP000013970913,4MDP000030348514,0MDP0000796828 MDP000069551214,1MDP000030411314,6MDP000025008015,2MDP000037263215,4MDP000016131715,8MDP000026402415,9MDP000031939616,1MDP000011881016,3MDP0000601491 MDP0000235175 MDP0000417927MDP000041792916,4MDP0000229007 MDP0000656152 MDP0000656154MDP0000153000 MDP000027190316,5

MDP0000120467 MDP000069633316,6MDP0000204678 MDP0000875642 MDP0000293051MDP0000293052 MDP000031604616,7

MDP0000247490 MDP000032244017,1MDP000038646017,3MDP000031997917,6MDP000092921317,7MDP000089205717,9MDP000049328418,6MDP0000183226 MDP0000181583 MDP0000179718MDP000023407322,4MDP000077848622,7MDP0000242552 MDP000012212223,6MDP000046043024,7MDP000019984025,2MDP000014703025,3MDP000016553426,1MDP0000725651 MDP000068999126,3MDP0000280921 MDP000020948326,5MDP000051585528,2MDP000042826528,3MDP000011981129,5MDP000021737329,6MDP000081108130,5MDP000030709433,2MDP0000234323 MDP000067312833,3MDP000040108633,8MDP000024362833,9MDP0000496268 MDP0000310904 MDP000023660534,9MDP000023749935,1MDP0000237498 MDP0000235118 MDP0000275309MDP0000171866 MDP000032439835,2

MDP000018370035,3MDP000018533335,4MDP000072327736,4MDP000077658336,7MDP000015924036,9MDP0000375330 MDP0000204319 MDP0000164293MDP0000204521 MDP000056902637,1

MDP0000223243 MDP0000181169 MDP000049284537,2MDP0000548790 MDP000018601137,4MDP0000132805 MDP000085876337,8MDP000081258638,0MDP000019316738,2MDP000089576839,0MDP0000514358 MDP000029149939,1MDP000021829239,6MDP0000276665 MDP000025628039,7MDP000015061039,8MDP0000391619 MDP000019640440,7MDP0000311020 MDP000021935141,1MDP0000300382 MDP000067598241,5MDP000038151441,7MDP000083713942,8MDP000043405943,4MDP000046821745,0MDP000012284746,8MDP000016442946,9MDP0000517601 MDP000021271247,8MDP000026751348,8MDP000013773348,9MDP000025904449,1MDP000095005749,4MDP0000137816 MDP000024297949,5MDP0000800550 MDP000022477949,7MDP000075021749,9MDP000026829650,4MDP000013618050,7MDP0000299959 MDP000029896550,8MDP000084287751,0MDP0000139343 MDP000025084951,1MDP000022430251,4MDP0000219737 MDP0000393617 MDP000019591651,5MDP000027685951,8MDP000021635752,6MDP000052865852,7MDP000027584454,2MDP0000174149 MDP000015507354,8MDP000073346855,0MDP000027831356,3MDP000012640457,7MDP0000233925 MDP0000233926 MDP000027877058,1MDP000027889258,5MDP000015889559,8MDP000065406859,9MDP000094651560,2MDP000087389364,6MDP000018149065,5MDP000091692067,2MDP000030675467,4MDP000024856768,0MDP0000124584 MDP000012458568,7MDP000058940368,8MDP000020184469,2MDP0000939384 MDP000081854269,4MDP000084391370,8MDP000064497970,9MDP000022894272,1MDP000061102272,4MDP000047554972,6MDP000025795374,1MDP0000229843 MDP000031880174,7MDP000025767475,6MDP000094342676,4

chr_5

MDP00003093311,1MDP00002873001,9MDP0000330698 MDP00003213382,0MDP0000233260 MDP00001427282,1MDP00007023552,2MDP0000191344 MDP00001672083,1MDP00001639304,1MDP00004518274,2MDP0000299637 MDP00002364384,3MDP00002092834,4MDP00007025574,5MDP00006648414,7MDP00004075725,1MDP0000060934 MDP00002829455,2MDP00002331645,7MDP0000563404 MDP00006169495,8MDP00002124655,9MDP00005467926,1MDP00002513396,5MDP00004192976,6MDP00001855538,2MDP00001394858,3MDP00006215458,4MDP0000911336 MDP00007727318,9MDP00001194469,4MDP000002916810,4MDP000079491311,2MDP000021481112,5MDP000020389513,5MDP000012166914,5MDP000020713414,7MDP000025950214,8MDP0000300492 MDP000016834114,9MDP000016536415,3MDP0000127230 MDP000023471416,3MDP000042332916,9MDP0000248311 MDP000024831217,2MDP000020806917,3MDP0000240641 MDP0000360447 MDP000024064319,1MDP000007167719,9MDP000022760620,4MDP000076201921,0MDP000049127122,5MDP000013650022,6MDP000090442123,7MDP000084319123,8MDP000078893426,7MDP000025025427,3MDP000085025529,4MDP000051285029,9MDP000087325830,0MDP000043572230,3MDP000083706531,7MDP0000198054 MDP000015505731,8MDP000013024432,7MDP000026039333,0MDP000024660833,1MDP000013303733,3MDP000013995034,0MDP0000273365 MDP000027584035,4MDP000017296335,6MDP000026892836,3MDP0000710285 MDP000024255436,7MDP000072951436,9MDP000016060037,0MDP000045170537,2MDP0000762302 MDP000024106337,4MDP0000263768 MDP000083666139,0MDP000031238239,2MDP000013126741,8MDP0000718765 MDP000057374642,9MDP000013222643,0MDP000031919443,1MDP000067055943,3MDP0000135108 MDP000022939144,9MDP000019353545,4MDP000022358045,5MDP000022867145,7MDP000014098045,8MDP000051368545,9MDP0000148461 MDP000020704846,6MDP000026482747,0MDP000021526947,1MDP0000137872 MDP000030071247,9MDP000030826148,0MDP000073850548,1MDP0000239877 MDP0000313569 MDP0000550728MDP0000202881 MDP000019809448,2

MDP000030187148,3MDP0000193127 MDP0000193128 MDP000019312948,9MDP000091172449,0MDP000028867049,9MDP000077283550,0MDP0000575443 MDP000019048950,3MDP0000461555 MDP000028871551,0MDP000048938451,2MDP000030758251,3MDP000057422251,4MDP000021802051,6MDP000014320851,7MDP000023484951,8MDP0000189019 MDP000091731551,9MDP0000155743 MDP000015574652,0MDP000016677953,3MDP0000235213 MDP0000246482 MDP000015394953,5MDP000087933753,6MDP000050915753,7MDP000024232754,2MDP0000230839 MDP000095171455,5MDP000020023155,7MDP000038778759,0MDP000037518159,7MDP000059520059,8

chr_6

MDP00002822291,2MDP0000268306 MDP00001675971,4MDP00001335291,5MDP0000280559 MDP00004796522,4MDP0000143749 MDP00007686672,5MDP00001400662,9MDP00008972423,0MDP0000615769 MDP00002531293,6MDP00001423983,7MDP00007164964,1MDP0000012534 MDP00008644424,2MDP00000125414,3MDP00002619414,4MDP00002144724,5MDP00001741684,6MDP0000279287 MDP0000178268 MDP00001693114,7MDP0000448747 MDP00001645296,4MDP0000299504 MDP0000138811 MDP00003780417,5MDP00002540528,1MDP00004112748,2MDP00007726338,8MDP000023165410,4MDP000018655811,5MDP0000218227 MDP000014696911,6MDP0000718066 MDP000068193613,9MDP000013689414,5MDP000092369014,6MDP000012014714,7MDP000025799515,5MDP000032052415,7MDP000025675916,5MDP000029964816,6MDP000021510617,4MDP0000283197 MDP000061165317,6MDP0000306498 MDP0000244964 MDP0000299884MDP0000244965 MDP000020444917,7MDP000089489517,8MDP0000259085 MDP000031694317,9MDP000066812218,0MDP0000289945 MDP0000241771 MDP000031910718,1MDP000030405919,0MDP000012712319,4MDP000065840919,5MDP0000523205 MDP000026435119,8MDP000042527020,0MDP000029399620,1MDP000077726020,2MDP0000156057 MDP000013598221,2MDP000016886121,9MDP000070875822,1MDP000021660522,6MDP0000258167 MDP000025673023,1MDP0000297071 MDP000020077323,7MDP0000128879 MDP0000174791 MDP000023337023,8MDP000018520924,4MDP000025619524,5MDP000019390224,7MDP000019126725,8MDP0000161897 MDP000012777127,1MDP000085189328,0MDP0000498999 MDP000022871328,5MDP000043954032,3MDP000069560432,5MDP000017544632,8MDP000078865532,9MDP000018470635,8MDP000014885737,3MDP000078396640,1MDP000022832840,4MDP000011903140,5MDP0000909869 MDP000058761440,6MDP000055495041,0MDP000085793741,1MDP000017380942,1MDP000070588942,2MDP000024789642,4MDP0000435100 MDP000012324842,6MDP0000218810 MDP000025761444,2MDP000014295745,6MDP000013348547,6MDP000013194547,7MDP000019420648,2MDP0000194603 MDP000064510548,4MDP0000575835 MDP0000311190 MDP000021556450,9MDP0000294573 MDP0000231843 MDP0000231845MDP000083518051,0MDP000030304151,1MDP0000126141 MDP000024994751,2MDP000074547551,7MDP0000552625 MDP000027550951,8MDP000082999851,9MDP000053600452,7MDP000030741053,1MDP000024320554,4MDP000076289554,6MDP000022759854,7MDP000013080254,8MDP000021676557,1MDP000056316557,6MDP000022649758,6MDP0000280968 MDP000077406658,8MDP000017273659,2MDP000027472359,8MDP0000138052 MDP000049379560,4MDP000024144760,7MDP000078665061,2MDP000087565461,3MDP000019101761,6

chr_7

MDP0000839414 MDP00001224780,5MDP0000134342 MDP00002406130,9MDP0000306022 MDP00001511641,0MDP00002641731,4MDP00002411261,5MDP00001476351,8MDP0000282828 MDP00003008202,3MDP00002201682,7MDP0000141335 MDP00002959022,8MDP00005219343,3MDP00005768893,8MDP00002058234,2MDP00001352304,7MDP00002275775,1MDP00002003556,1MDP00008758386,9MDP00002683207,2MDP00001753757,5MDP00002387737,7MDP0000441757 MDP00006387867,9MDP00004243988,1MDP0000225501 MDP00009108578,2MDP0000231298 MDP0000252854 MDP00002528558,4MDP00004406548,5MDP00005284298,7MDP00003217009,3MDP00004642769,6MDP00001866559,7MDP00002427509,8MDP000028553510,4MDP000093065513,6MDP000078716813,7MDP000089110813,8MDP0000190950 MDP000015620714,1MDP000073720214,4MDP000024446914,7MDP000029632414,8MDP000025970614,9MDP0000253285 MDP000012381615,0MDP000018329915,1MDP000038153115,2MDP0000181479 MDP000021284117,1MDP000026970117,5MDP0000159571 MDP000022883817,6MDP0000263961 MDP0000307516 MDP000023640417,7MDP000029652018,1MDP000024337518,2MDP000031178818,4MDP000042594219,2MDP0000299555 MDP000048054719,7MDP000040574820,3MDP000014663020,4MDP000031918720,8MDP000072198721,4MDP0000421809 MDP000019507222,8MDP000031895123,0MDP000014163523,5MDP000017692723,9MDP0000249929 MDP000049607124,6MDP000026020324,8MDP0000498407 MDP000059059624,9MDP000027624126,6MDP000014582528,1MDP000029249228,4MDP0000140166 MDP000020082228,6MDP000015282129,9MDP0000626334 MDP000043500730,6MDP000012988230,8MDP000025856231,1MDP000024598831,7MDP000024213531,8MDP0000649866 MDP000022508832,1MDP000070173432,2MDP0000123894 MDP000012389332,4MDP0000174414 MDP000032073932,6MDP0000713910 MDP000052381232,7MDP000051699133,4MDP0000178787 MDP000023016933,6MDP0000269843 MDP000058062934,6MDP000013115835,6MDP0000308745 MDP000038545136,4MDP000075373637,7MDP000024165038,7MDP0000431701 MDP0000193584 MDP000027870739,0MDP000053688139,3MDP000013596641,8MDP000073466141,9MDP000022808442,1MDP000017115442,2MDP000028726644,3MDP000046242944,4MDP000069016844,7MDP000026040444,8MDP000043766445,1MDP000073747245,4MDP0000184157 MDP000024225546,3MDP000071655146,5MDP000032028346,8MDP0000739406 MDP000027668847,8MDP0000215926 MDP0000631089 MDP000013575847,9MDP0000199273 MDP000062998548,1MDP000018879448,9MDP0000498524 MDP0000200450 MDP0000290801MDP000030612149,0

MDP0000553484 MDP0000215525 MDP0000735095MDP000089950849,1

MDP000076976449,2MDP000027439049,7MDP0000548763 MDP000028422049,8MDP000023901152,3MDP000031494252,4MDP000054371853,0MDP000032056353,5MDP0000278387 MDP0000477771 MDP000030944553,6MDP000019810853,7MDP000013733053,8MDP000022807054,1MDP000028735055,1MDP000025897956,5MDP000029782156,6MDP000028664357,4MDP0000139057 MDP000048332159,1MDP000031799359,7MDP000045402760,8MDP000031347661,4MDP000012320061,8MDP000031974662,5MDP000028429763,1MDP000083616563,2MDP000025929463,6MDP000025929663,7MDP000052719063,8MDP0000166457 MDP000030083664,7MDP0000619822 MDP000038853764,8MDP0000211931 MDP000027764365,0MDP0000752882 MDP0000463584 MDP000079365665,2MDP0000552871 MDP000021246166,3MDP0000950422 MDP000025936066,4MDP000068247166,6MDP0000749719 MDP000081629767,1MDP000017293367,3MDP000067451467,8MDP0000925348 MDP000018860469,3MDP0000273450 MDP0000314729 MDP000015048569,5MDP000021948269,6MDP0000188229 MDP0000221319 MDP0000273242MDP0000162976 MDP000020086770,8

MDP000045381370,9MDP000016877371,1MDP0000060059 MDP000006005671,4MDP000045647671,5MDP000017878271,7MDP000025927973,1MDP0000491658 MDP000074710574,6MDP0000303333 MDP0000442215 MDP000056726474,9MDP0000445110 MDP000031576475,0MDP0000192806 MDP000019395375,3MDP0000483351 MDP000012026975,5MDP0000274003 MDP000017016275,8MDP000075653675,9MDP000018790976,6MDP000024009476,7MDP000070637978,5MDP0000738631 MDP000017971979,0MDP0000275938 MDP000029860179,2MDP000024779180,3MDP0000191559 MDP000015152180,5MDP000031790780,6MDP0000466557 MDP0000428573 MDP000028702981,3MDP0000564884 MDP000021288181,8MDP000016492381,9MDP0000929655 MDP000048520582,0MDP000027756082,7MDP0000388002 MDP0000308015 MDP000026313783,1MDP000029818284,0MDP000085924684,3MDP000017855484,7MDP000011923085,3

chr_8

MDP00005279950,7MDP0000247734 MDP00002686521,1MDP00003093821,3MDP0000154734 MDP0000599569 MDP00001234671,7MDP00002641871,9MDP00002961232,0MDP0000399538 MDP0000417953 MDP00008957502,1MDP00002816892,3MDP0000288010 MDP0000285734 MDP00001286792,7MDP00003750392,9MDP0000283867 MDP0000256522 MDP00002388813,1MDP0000225620 MDP00006635643,6MDP00001827223,7MDP0000258005 MDP00005581794,3MDP0000231545 MDP00007492875,0MDP00008644266,4MDP0000250518 MDP00005188857,0MDP0000320993 MDP0000297698 MDP0000201555MDP0000482731 MDP0000186581 MDP00002863227,1

MDP00004525597,2MDP00003206917,6MDP00007307387,7MDP0000432497 MDP00005745548,1MDP00004521638,4MDP00002767658,5MDP0000191788 MDP0000276536 MDP00002425968,8MDP00001791458,9MDP00001965549,0MDP0000679320 MDP0000230835 MDP0000176250MDP0000230836 MDP00003220919,9MDP0000592879 MDP0000280885 MDP0000586116MDP0000261103 MDP0000280886 MDP000027861910,0

MDP000022111410,2MDP0000450991 MDP000045208310,8MDP0000366019 MDP0000289858 MDP000060548211,0MDP0000189308 MDP000013273811,1MDP0000143531 MDP000022385111,3MDP000024553811,6MDP000040775511,9MDP0000126997 MDP000022313713,1MDP000015358913,3MDP0000152089 MDP000018765714,3MDP000022387914,4MDP0000642867 MDP0000278157 MDP0000703981MDP000032802514,5

MDP000056459216,2MDP000036187616,7MDP000019832018,2MDP000024353918,3MDP000014101818,6MDP0000290494 MDP000019815218,8MDP000054905618,9MDP0000561662 MDP000013139719,2MDP0000244701 MDP000092355919,4MDP000019635819,5MDP000072598419,6MDP000045311419,7MDP000041393321,6MDP000031364321,7MDP0000190889 MDP000018617521,8MDP000060392622,8MDP0000670267 MDP000067026823,2MDP000026195923,3MDP0000256105 MDP000025807823,5MDP0000267341 MDP0000708928 MDP000025022323,6MDP000012467223,7MDP000059938823,9MDP000090444524,3MDP000041890024,4MDP0000587103 MDP000028914924,8MDP0000279292 MDP000029991525,3MDP000016497725,4MDP000086665525,7MDP000026985925,8MDP0000176595 MDP0000156988 MDP0000120322MDP0000322379 MDP000087948026,0

MDP000018328326,1MDP000018366027,0MDP0000292218 MDP000019439227,2MDP000042613827,3MDP0000251626 MDP000031990627,4MDP000025465027,8MDP000022490728,2MDP0000128461 MDP000083295228,3MDP000088855328,9MDP0000223496 MDP000050524729,0MDP000031097629,2MDP0000814694 MDP000027267129,5MDP0000271370 MDP0000140678 MDP000087366729,7MDP0000167035 MDP000032425930,1MDP000018332631,7MDP0000231284 MDP000023128532,3MDP000022728734,7MDP000024298034,8MDP000024173635,0MDP0000034165 MDP000006086935,1MDP000015854435,7MDP000022928035,9MDP000050682536,0MDP0000617956 MDP000073350636,1MDP000054512236,2MDP000078264236,5MDP0000187518 MDP000076774336,6MDP000020943237,0MDP0000394374 MDP0000245843 MDP000022657138,1MDP000075427538,2MDP000083224638,9MDP000024618439,0MDP000025811639,2MDP000064682339,4MDP000068666139,8MDP000068666639,9MDP000057574040,0MDP0000121041 MDP000031181540,3MDP0000139953 MDP0000236911 MDP000027064540,7MDP0000652631 MDP000012593941,2MDP000028024041,5MDP000006075341,8MDP0000273574 MDP000042352942,4MDP0000315574 MDP000079637942,5MDP0000291070 MDP000017040244,1MDP000040358044,8MDP0000168682 MDP000016868345,1MDP000024581345,3MDP000061120445,9MDP000014376546,0MDP000031965946,5MDP000016624546,7MDP000019493547,6MDP000016409548,4MDP000013741549,1MDP000079078850,9MDP0000141206 MDP000017839551,1MDP000021184851,2MDP000087104252,8MDP000012624555,4MDP000051803255,5MDP000025463256,1MDP000071631556,3MDP0000580327 MDP000081944057,9MDP000011986461,3MDP000013040061,4MDP000029152263,4MDP000020085163,9MDP000063869164,4MDP000030253166,0MDP000085227166,1MDP000072205268,2MDP000090282268,5MDP000016605969,0MDP0000271809 MDP000089219869,2MDP0000178326 MDP000030630271,1MDP000014736873,9MDP0000397540 MDP000016112374,3MDP0000218344 MDP000025289074,5MDP000025196675,3MDP000021869975,4MDP0000552328 MDP000024677575,5MDP000012380875,6MDP000048658975,9MDP000086503276,8MDP0000714374 MDP000073133077,2MDP000025227477,8MDP000052972678,1MDP000013872180,1MDP000042062880,2MDP000032303680,5MDP0000121788 MDP0000259640 MDP000078541380,6MDP000027698280,7MDP0000138004 MDP0000188551 MDP000040012980,8MDP0000294251 MDP000013746181,4MDP000019667782,1MDP000013410582,3MDP0000652760 MDP000012797682,4MDP0000657701 MDP000084776682,5MDP0000155054 MDP000014584182,8MDP000018226583,5MDP000013076985,6MDP000041820185,7MDP000025899985,8MDP000086993985,9

chr_9

MDP00003792882,2MDP00008399213,1MDP0000242242 MDP00001447903,9MDP0000286230 MDP00004471494,5MDP00002083345,3MDP00002041256,5MDP0000200486 MDP0000720967 MDP00004665466,6MDP0000224878 MDP00002426566,7MDP00002350287,0MDP00003195007,2MDP00001719907,3MDP00003440268,2MDP0000270062 MDP000024813010,6MDP0000686217 MDP000014941110,8MDP000025835910,9MDP0000245702 MDP000013589811,1MDP000074660511,4MDP000026463412,1MDP0000222941 MDP000021899212,3MDP000030004312,9MDP000084994414,7MDP000015900015,8MDP000057692215,9MDP000021559017,1MDP000029068017,5MDP000018359317,9MDP000028360618,6MDP000028108018,7MDP000076237318,9MDP000015967019,2MDP000013093120,5MDP0000587659 MDP000065001720,9MDP000074151421,0MDP000017230321,2MDP000013756122,0MDP000013187426,3MDP000020563726,6MDP000025447029,2MDP0000412939 MDP000075265629,8MDP0000132452 MDP0000147628 MDP0000699607MDP000067889131,3

MDP0000491020 MDP000024956431,5MDP000022357032,2MDP000012552032,3MDP000015477732,4MDP000056804533,4MDP000048058133,6MDP000019258634,8MDP000014470335,3MDP000028098037,0MDP000018163037,1MDP000020511338,4MDP0000554450 MDP000050922940,3MDP0000302503 MDP000017182242,1MDP000028964242,5MDP0000679946 MDP000023576542,6MDP000015686643,4MDP000030423643,8MDP0000284467 MDP0000668966 MDP000025087643,9MDP000032001744,3MDP000016864645,0MDP000032673445,4MDP000069703046,0MDP0000246388 MDP000085567146,7MDP0000187369 MDP000028691546,9MDP0000139773 MDP000093486647,2MDP0000163720 MDP000026912647,3MDP000087877347,4MDP000036390448,2MDP000022427548,6MDP000013170248,7MDP0000872262 MDP000041555848,8MDP000062621548,9MDP000045750949,1MDP000028196549,2MDP0000176747 MDP000017674949,4MDP0000176753 MDP000001008649,5MDP0000220092 MDP000013770549,7MDP000081380549,9MDP000013068651,5MDP000070212051,9MDP000022515952,2MDP0000310875 MDP000021914652,4MDP000021914852,5MDP000019078855,7MDP000056600556,5MDP000079136456,6MDP000013326257,1MDP000084041758,8MDP000014582759,0MDP000026873259,2MDP000027460659,4MDP000030942559,6MDP000011959059,7MDP000026489460,3MDP000032416660,6MDP000031660961,3MDP000013391862,1MDP0000732246 MDP0000711750 MDP000032087262,6MDP000013824963,4MDP0000689946 MDP000043068263,9MDP0000319451 MDP000031149264,1MDP000017965064,2MDP000030935164,4MDP000081452464,7MDP0000287570 MDP000021052164,8MDP000028735865,3MDP000027284365,4MDP000082112466,1MDP000012088066,7MDP000012088166,8MDP000030586167,4MDP000074078769,3MDP000049674569,4MDP0000199152 MDP000029890369,5MDP0000245233 MDP000052552769,9MDP000021015570,0MDP000017939672,8MDP000018154472,9MDP000021763374,0MDP0000289069 MDP000093565274,3MDP000019588574,8MDP0000274205 MDP000025874474,9MDP000029438475,0MDP000080745675,9MDP0000309469 MDP000020551576,3MDP0000265913 MDP000029940276,7MDP000028558976,8MDP000013456676,9

chr_10

MDP00003923380,0MDP0000928605 MDP0000169709 MDP00007336210,1MDP0000201513 MDP0000305929 MDP0000172804MDP00003141910,7MDP00005235791,0MDP00008433031,4MDP0000189193 MDP0000130808 MDP0000268101MDP00003202151,5

MDP00006222411,6MDP00002341662,7MDP00005654022,8MDP00008767383,3MDP0000528870 MDP00003076854,2MDP0000182395 MDP00004857764,5MDP00002958125,6MDP0000277666 MDP00003003215,9MDP00002010116,0MDP0000203847 MDP0000562585 MDP0000565880MDP00002448736,1

MDP0000162617 MDP0000264453 MDP00002448776,3MDP0000611903 MDP00006187746,4MDP00003013477,1MDP00001692878,0MDP00001987369,0MDP0000282880 MDP00001782149,1MDP0000215099 MDP00001306539,6MDP000046470411,3MDP000022934811,5MDP0000940078 MDP0000297791 MDP0000305387MDP0000893848 MDP000026287811,7

MDP0000144544 MDP0000215725 MDP0000155454MDP000013850011,8

MDP0000265416 MDP0000507969 MDP000015887612,2MDP000038272012,6MDP000027709312,8MDP000026706412,9MDP000093599613,0MDP000019574113,3MDP0000172662 MDP000030914213,4MDP0000382514 MDP0000859587 MDP000039663013,7MDP0000686301 MDP0000471565 MDP0000739392MDP0000222559 MDP0000156246 MDP0000263453MDP0000313145

13,8

MDP000027605713,9MDP0000173539 MDP0000902216 MDP0000376869MDP0000396403 MDP0000379060 MDP000022976314,0

MDP000016782914,4MDP000023303715,1MDP000016349015,3MDP000016601615,7MDP0000148746 MDP0000171771 MDP000039411616,1MDP000028995516,5MDP000026413116,6MDP000016301716,7MDP0000323136 MDP000009203316,8MDP000050418317,8MDP000045671618,3MDP000018585618,4MDP000026756118,5MDP0000551467 MDP000030462519,3MDP000020997421,1MDP000092183422,2MDP000065309522,6MDP000090721822,7MDP000030746723,6MDP0000885802 MDP000085932524,7MDP000064479725,2MDP000014086425,5MDP000018160625,8MDP000017301126,2MDP0000196330 MDP000024647026,7MDP000041627926,8MDP0000228273 MDP0000701129 MDP000021349426,9MDP000041278127,3MDP000025588427,7MDP000049864528,4MDP000027444228,8MDP000037597128,9MDP0000265616 MDP000019198129,1MDP000069143129,5MDP0000125980 MDP000080798429,6MDP000059303131,0MDP000080474131,4MDP000031176531,5MDP0000285555 MDP000021355535,7MDP000028939736,6MDP0000163058 MDP000023043437,1MDP000090654237,2MDP0000629527 MDP0000311969 MDP000054263338,6MDP0000153227 MDP0000186640 MDP0000286362MDP0000292291 MDP0000173000 MDP000063181338,7

MDP0000139929 MDP0000243770 MDP0000483239MDP000014624839,5

MDP000029318443,0MDP000023902643,5MDP000024011345,9MDP000068416947,3MDP000018368248,6MDP000052885751,2MDP0000853065 MDP000024643653,0MDP0000157209 MDP000023301053,3MDP000088212754,0MDP0000177696 MDP0000202631 MDP000030857654,1MDP000013812254,2MDP000020619954,6MDP000020686854,7MDP0000233948 MDP000023384355,0MDP0000391188 MDP000049014957,6MDP000031768658,1MDP0000165921 MDP000026480358,5MDP000040244459,4MDP000029650859,5MDP000031711960,1MDP000083678160,4MDP000069376560,7MDP0000130635 MDP000027697660,9MDP000027484761,0MDP0000380592 MDP000014004161,1MDP000025951161,9MDP000013457262,5MDP0000213111 MDP000028941362,6MDP000086858764,4MDP000044231064,8MDP000078830464,9MDP0000180890 MDP0000766342 MDP000016278365,4MDP000024437765,5MDP000013369866,1MDP000082131467,7MDP000028480867,9MDP000065566668,2MDP000057010269,9MDP0000169346 MDP000016963570,0MDP000023062771,1MDP000026281572,6MDP000020589072,8MDP000030446272,9MDP0000614281 MDP000088045373,2MDP000022568074,4MDP000023124576,4MDP0000138860 MDP000021435276,9MDP000012597577,1MDP000020438177,9MDP0000288465 MDP000028846878,3MDP0000126944 MDP000012694678,4MDP0000603805 MDP0000126947 MDP0000126948MDP000032003978,5

MDP0000929168 MDP000023196278,6MDP000013662379,0MDP0000202282 MDP000017421679,4MDP000020229279,5MDP0000234798 MDP000094932779,6MDP000022680979,8

chr_11

MDP00001840690,4MDP00001775471,3MDP00007700891,5MDP00002543721,9MDP00002284072,2MDP00001790363,9MDP0000179040 MDP00002303084,0MDP0000126707 MDP0000151497 MDP00008336414,2MDP0000177486 MDP00001441054,9MDP00008963076,0MDP00002874236,7MDP00002062127,0MDP0000281064 MDP00002271157,8MDP0000523644 MDP000071302410,1MDP000023233810,2MDP000029714210,6MDP000030952113,2MDP0000871361 MDP000070362617,2MDP000087480017,4MDP0000168416 MDP0000220329 MDP000014790218,0MDP000079326819,1MDP0000814798 MDP0000313984 MDP0000169669MDP000021158119,2

MDP000022843719,4MDP000013810221,3MDP000026221022,2MDP000061551425,1MDP000025522325,3MDP000078466526,7MDP0000279249 MDP000084191828,0MDP000078770128,1MDP000029605028,2MDP0000285032 MDP0000250395 MDP0000688348MDP000011629628,3

MDP0000057153 MDP000068837628,4MDP0000257406 MDP0000682530 MDP000017314328,6MDP000059594128,9MDP000031150029,1MDP000083617029,3MDP000046841130,6MDP000013795431,4MDP000040686032,9MDP000004142133,9MDP000028050634,5MDP0000665087 MDP000071515434,6MDP0000123864 MDP000037095634,8MDP0000370957 MDP0000238208 MDP000093184234,9MDP000019243435,0MDP0000460051 MDP000056102635,4MDP000018004336,0MDP000069680437,6MDP000080367437,7MDP0000179216 MDP000018419537,8MDP000015737038,2MDP0000388769 MDP000013907538,5MDP000016724639,5MDP0000756357 MDP000018865539,6MDP0000246825 MDP0000560923 MDP000018525639,9MDP000060033642,3MDP0000586302 MDP000026451442,6MDP0000908969 MDP000027491142,8MDP000016364544,2MDP000026836444,5MDP0000201945 MDP000059842844,6MDP000015681545,4MDP000032262745,9MDP000032135347,8MDP000074323948,3MDP000013876448,5MDP000011909248,6MDP0000255768 MDP000020596248,8MDP000014862648,9MDP000024423150,1MDP000011922350,2MDP000017336050,5MDP000022360951,6MDP0000250924 MDP0000139446 MDP000025092751,7MDP000044871551,9MDP0000494976 MDP0000832632 MDP000025236952,2MDP0000278118 MDP000027811952,3MDP000034100852,4MDP0000390437 MDP0000651396 MDP000030466654,1MDP0000242852 MDP000016108455,9MDP0000492744 MDP000036080856,4MDP000050876156,8MDP0000319736 MDP000059830358,0MDP000067245458,2MDP0000750456 MDP000028741658,9MDP000017877859,3MDP0000951202 MDP000088031260,4MDP000024401860,5MDP0000296025 MDP0000195385 MDP0000298852MDP000014610860,7

MDP0000718993 MDP000063400661,2MDP0000912745 MDP000025308561,3MDP0000219509 MDP0000432773 MDP000052452261,6MDP0000706439 MDP000070915361,7MDP0000902285 MDP000074704561,8MDP000015485561,9MDP000014194762,4MDP0000765613 MDP000069459762,5MDP0000285074 MDP0000661371 MDP0000285078MDP0000306486 MDP000030648762,6

MDP000021025162,8MDP000082412863,0MDP000046013963,2MDP0000754989 MDP000075499263,3MDP000012009863,4MDP000015634363,9MDP000016214364,0MDP000017009564,7MDP0000286498 MDP0000186817 MDP000018681864,9MDP000020215665,0MDP000029026365,1MDP0000307605 MDP0000834768 MDP000059944965,2MDP000063463065,4MDP000018105365,6MDP0000802803 MDP000029450466,0MDP000027826066,1MDP000086913766,3MDP000020316866,8MDP000030989966,9MDP0000296741 MDP000020034067,3MDP0000125303 MDP0000168536 MDP0000520035MDP000017209268,9

MDP0000146677 MDP0000081005 MDP0000120271MDP0000312394 MDP000026388469,0

MDP000002541369,3MDP000067213169,8MDP000093130270,8MDP000017640972,0MDP000078537972,1MDP000025502572,4MDP000027036573,0MDP0000945260 MDP0000663301 MDP0000234335MDP000075617373,1

MDP000023117273,5MDP000087168973,7MDP000032232975,7MDP000018404475,8MDP000013272375,9MDP0000260362 MDP000025175976,1MDP000087108076,3

chr_12

MDP00002483310,3MDP00003113040,5MDP00001709070,6MDP00001887500,7MDP0000130290 MDP00005614770,8MDP0000297336 MDP00002081052,2MDP00001518252,3MDP00002717703,1MDP0000171235 MDP0000242396 MDP0000284687MDP0000306441 MDP00003068373,2

MDP0000245769 MDP0000293915 MDP0000251013MDP0000213733 MDP0000299199 MDP0000192132MDP0000887754 MDP0000815791 MDP0000546004

3,3

MDP00003112553,8MDP0000549961 MDP0000503044 MDP00004975813,9MDP00001665704,4MDP00002777755,2MDP00002594955,9MDP00003109816,1MDP0000239442 MDP0000547788 MDP00002416626,2MDP0000743350 MDP00001199566,4MDP0000145555 MDP00003018846,8MDP00001289247,0MDP00001658457,1MDP00002714207,2MDP00001133367,3MDP00008918998,5MDP0000322436 MDP00006862898,8MDP00001492228,9MDP0000269921 MDP0000197683 MDP00003269069,3MDP00002199079,8MDP00001932169,9MDP000065562310,0MDP000024047410,3MDP000012578210,4MDP000084951410,5MDP000048144810,9MDP000056011211,0MDP000018676511,5MDP000029432411,7MDP000021097912,0MDP000027385112,4MDP0000281784 MDP000045426912,5MDP000019557913,3MDP000031231613,8MDP0000213640 MDP0000228207 MDP000085985715,0MDP000083415615,1MDP000023995815,2MDP000020914815,6MDP0000324249 MDP000082740016,9MDP000074092717,0MDP000070551017,1MDP0000250058 MDP000081536817,3MDP000072981717,7MDP0000319156 MDP000049189818,0MDP000063169818,1MDP000075756519,1MDP000015466819,6MDP000021262120,1MDP000064646720,4MDP000030901420,7MDP0000155347 MDP000087827921,0MDP000093623221,1MDP0000370413 MDP000079208821,2MDP000012651722,0MDP000020196624,5MDP000039012124,9MDP000022684225,2MDP000026300825,4MDP000032398725,9MDP0000279891 MDP0000279892 MDP0000905103MDP000021904126,2

MDP000030373527,1MDP000031093627,7MDP000029641628,4MDP000022640528,8MDP000019237228,9MDP0000305934 MDP0000212539 MDP000018320429,2MDP0000133148 MDP000018683429,3MDP000014639029,4MDP000020209429,5MDP000052371529,7MDP0000823143 MDP000031487231,3MDP000065607831,6MDP000025838731,7MDP000085795832,4MDP0000165867 MDP000018468732,5MDP000014217433,2MDP000027151333,4MDP000035043133,6MDP000018934735,0MDP000028845235,1MDP000027675035,3MDP000012017635,9MDP000019315136,7MDP0000236701 MDP000013292636,9MDP000012897938,2MDP000022138338,3MDP000058140638,4MDP0000293214 MDP000030445538,5MDP0000686191 MDP0000389664 MDP000078585238,6MDP000059264938,7MDP0000285581 MDP000024649339,5MDP000065869641,0MDP000021116541,1MDP000077814041,3MDP000023994741,4MDP000014386044,6MDP000031877246,2MDP000059462146,9MDP000081312947,2MDP000020492947,3MDP000028909847,4MDP000025747447,8MDP000013728349,5MDP000031342550,3MDP000031085454,6MDP000009692355,1MDP000019639455,2MDP000030314255,3MDP000021386455,5MDP000019560856,2MDP000021318760,1MDP000013342362,0MDP000019763862,2MDP000020593863,0MDP000032241864,1MDP000092018964,8MDP000081949965,2MDP000027675865,3MDP000082574965,4MDP0000133854 MDP000082992565,5MDP0000127134 MDP000016720765,8MDP000024340468,9MDP0000801765 MDP000026273669,0MDP0000140747 MDP000014512369,3MDP0000194557 MDP000073104770,0MDP0000273194 MDP000016910870,1MDP000022395970,2MDP000082417871,2MDP000042819971,7MDP000075551171,8MDP000015493271,9MDP000021918472,1MDP000088709372,4MDP000018525372,7MDP0000431572 MDP000044189173,4MDP000008454673,6MDP0000145734 MDP0000285495 MDP000012555474,0MDP000022975574,4MDP000080032278,4MDP000074098178,5MDP000022274478,9MDP000020406679,2MDP000061924479,7MDP0000841540 MDP000021969680,0MDP000077428880,1MDP000014684880,9MDP0000121984 MDP000031692981,4MDP0000138669 MDP000055783681,6MDP000018133981,7MDP000013347682,0MDP000094504282,2

chr_13

MDP00001806830,2MDP00001283260,6MDP00005352740,9MDP0000939989 MDP00002894282,3MDP0000195376 MDP00004513653,0MDP00001216033,3MDP00001524005,7MDP00002524355,8MDP0000506233 MDP00002339215,9MDP00005584936,4MDP00001642977,0MDP00001764477,4MDP0000284245 MDP00005452139,1MDP0000163334 MDP0000183754 MDP00002215909,8MDP0000663451 MDP0000310711 MDP0000299960MDP000053449310,2

MDP0000182809 MDP0000178561 MDP0000162169MDP0000179051 MDP0000467510 MDP000061656510,3

MDP000029679112,7MDP000028753013,0MDP000028939213,1MDP000017622414,3MDP000062697815,0MDP000032023915,1MDP0000482268 MDP000030244016,3MDP000041242716,4MDP0000214409 MDP000022318416,5MDP000012769517,0MDP000076512317,1MDP000090999117,3MDP000088203317,4MDP000032032218,1MDP000018037618,3MDP0000218209 MDP000051314018,6MDP000077306821,9MDP000072209224,4MDP000075933624,7MDP000017742226,0MDP000016410631,4MDP0000129053 MDP000092272331,6MDP0000226447 MDP000031637931,8MDP000078381832,7MDP000079443933,1MDP000086855633,5MDP000032226438,2MDP0000126350 MDP000015544641,7MDP0000146144 MDP000055522041,9MDP0000146334 MDP000021534642,3MDP000014022943,4MDP000018828944,7MDP000047246244,8MDP000018331344,9MDP000056178845,0MDP000026690845,4MDP000031684345,6MDP000019027345,7MDP000023970145,9MDP000019023746,9MDP0000258032 MDP000066299947,4MDP000031384247,6MDP0000147080 MDP000080708748,0MDP000025380248,7MDP000025395248,8MDP000041072849,6MDP000026380150,0MDP000028962951,3MDP000059776751,7MDP0000394944 MDP000020138952,4MDP000032985153,4MDP000016115753,7MDP000028393353,8MDP0000846032 MDP000047943654,0MDP000023911454,1MDP000029300154,2MDP000030794355,3MDP000028046356,6MDP0000165481 MDP0000221713 MDP000015939556,9MDP000015848657,0MDP0000129051 MDP000027932657,1MDP000014249057,3MDP0000158799 MDP000068421657,4MDP0000324559 MDP000021217857,8MDP000029984658,2MDP0000910487 MDP0000218785 MDP0000218786MDP000017521559,0

MDP0000152070 MDP000026398159,1MDP0000153663 MDP0000291218 MDP0000151618MDP000019302559,9

MDP000012126560,0MDP000071527060,9MDP000031924861,0MDP000014226661,2MDP000028696061,3MDP000032639062,2MDP000028983662,3MDP000024286562,5MDP000090513562,6MDP000003965362,7MDP0000300361 MDP0000315837 MDP0000282599MDP0000157628 MDP000019737562,8

MDP000027320164,3MDP0000130785 MDP000077935864,4MDP000016002664,9MDP000031382065,0MDP000093371165,1MDP000029695865,8MDP000093104865,9MDP000013803566,1MDP000082361266,5MDP0000384932 MDP0000319849 MDP000023127466,6MDP0000656113 MDP000021259367,7MDP000086837268,4

chr_14

MDP00009168790,1MDP00001226240,6MDP00001475271,0MDP00002890431,5MDP00002282821,6MDP00002317181,7MDP00002252312,1MDP0000232577 MDP0000203740 MDP00001642772,9MDP0000308887 MDP00004549383,0MDP0000231650 MDP0000187703 MDP00001753093,1MDP0000146841 MDP00001902773,3MDP00001271013,5MDP00002305303,6MDP0000198037 MDP00005731784,2MDP0000275058 MDP0000296241 MDP00003029704,4MDP00003155334,5MDP00002214665,3MDP00002316685,4MDP00007563415,5MDP00001527745,6MDP0000617871 MDP00004848475,7MDP0000908951 MDP00002048385,8MDP00002494056,0MDP00002963036,2MDP00002904856,4MDP00006250096,9MDP0000123213 MDP00002781247,4MDP0000267601 MDP00001305837,9MDP0000219296 MDP00003099298,4MDP0000307237 MDP0000584567 MDP0000058337MDP00007158988,5

MDP00002426118,6MDP0000192227 MDP0000316545 MDP0000271304MDP00002713058,7

MDP00002785888,8MDP00008695899,1MDP00002286739,3MDP00002320089,4MDP00006036309,9MDP000068004210,2MDP0000177665 MDP0000200748 MDP000038189710,3MDP000014944710,5MDP000020364710,6MDP0000272940 MDP000051481210,8MDP000094576710,9MDP000028221313,1MDP000020519714,4MDP0000318601 MDP000014106214,8MDP0000280142 MDP0000429728 MDP000017826315,0MDP0000193822 MDP000026594215,3MDP000017453715,5MDP000033404717,3MDP000053469018,4MDP0000845683 MDP000084568518,7MDP000019145318,9MDP0000667743 MDP000027216419,6MDP000030985319,7MDP000026009219,8MDP0000762267 MDP000026795119,9MDP000027140520,2MDP000013121820,3MDP000063217320,4MDP0000526584 MDP0000121522 MDP000053478420,7MDP000019043021,1MDP000019671121,3MDP000030281521,4MDP000045879922,0MDP000065168922,6MDP000037625623,7MDP000053130124,0MDP000016438625,3MDP000021391625,9MDP0000389195 MDP000047750326,1MDP000016868126,2MDP000092131926,3MDP000029927728,4MDP000019546028,8MDP000023040229,6MDP0000290880 MDP000012431629,9MDP000027126830,0MDP0000270132 MDP000024784930,2MDP000025094730,8MDP000015630930,9MDP000025662131,2MDP000076624132,0MDP0000212975 MDP000061290932,8MDP000017545033,6MDP0000153231 MDP0000869545 MDP000075304133,7MDP000039675034,1MDP000032036034,2MDP000024085534,9MDP000043597135,0MDP000049427335,6MDP0000318427 MDP0000828007 MDP000031810135,9MDP000022958836,3MDP000020458236,4MDP000065258437,1MDP000032233038,0MDP000012401938,3MDP000024170338,5MDP000014817839,0MDP000087323539,1MDP000015193439,3MDP000036183839,5MDP000022067539,6MDP0000182782 MDP0000138064 MDP000025272339,7MDP0000259556 MDP000020659339,8MDP0000888095 MDP0000701077 MDP000025669639,9MDP0000424978 MDP000025906240,1MDP0000067999 MDP000021595841,3MDP000015707041,6MDP0000612482 MDP000061865041,7MDP000019898041,9MDP0000177299 MDP000021886842,1MDP0000576178 MDP000018506742,8MDP0000503341 MDP000023295242,9MDP000022670143,0MDP000037509243,4MDP000029017043,7MDP000051725743,9MDP0000799290 MDP000051726244,0MDP000020089646,0MDP000054601846,5MDP000078290847,0MDP000080494647,3MDP0000440622 MDP000056102247,4MDP000077895548,4MDP0000848702 MDP000039302248,6MDP000025866148,8MDP000015404649,8MDP0000665685 MDP000078728151,2MDP0000421802 MDP000041709551,6MDP000017085352,2MDP000016947352,9MDP000027349553,2MDP000027671153,3MDP0000124752 MDP000026005253,4MDP000025323153,5MDP000027563553,8MDP000072742656,0MDP000030966156,1MDP000067208857,2MDP000017359360,7MDP000018861061,3MDP000055723462,1MDP000016245662,3MDP000080494962,4MDP000014229263,1MDP000014723263,5MDP0000152668 MDP000024531265,2MDP000013252765,8MDP000039285966,0MDP0000654314 MDP000026765167,0MDP000092109468,0MDP0000159013 MDP000019885868,1MDP0000204900 MDP000018245568,6MDP000017996268,7MDP000029835269,2MDP000030356769,3MDP000017858671,4MDP000066653971,5MDP000087286871,6MDP000094091071,7MDP000022598071,9MDP000026115472,8MDP000068910573,0MDP000048528076,0MDP000012869576,6MDP000037538476,9MDP000012353079,5MDP000037140182,6MDP000012125884,4MDP000018037884,6MDP000014492285,3MDP0000453797 MDP000068381485,5MDP000030780986,3MDP000025853086,7MDP000024631986,8MDP000091089590,0MDP000017316097,4MDP000093346197,5MDP000003189598,5MDP000022478998,6MDP000027799998,9MDP000023211699,1MDP000012516799,6MDP0000736385100,3MDP0000309179 MDP0000762567100,7MDP0000809218101,8MDP0000181746102,0MDP0000258316 MDP0000289583102,7MDP0000196806 MDP0000297196103,0MDP0000470297103,7MDP0000191908104,0MDP0000682893 MDP0000744887 MDP0000769041104,1MDP0000846004 MDP0000295375104,2MDP0000234911105,2MDP0000194413105,4MDP0000090281106,3MDP0000644807106,6MDP0000759612106,8MDP0000794858107,8MDP0000578301108,3MDP0000129112108,7MDP0000134211109,0MDP0000602946110,3MDP0000163213111,7MDP0000052862 MDP0000688415 MDP0000269890MDP0000361449 MDP0000219282112,0

MDP0000375160 MDP0000192342112,1MDP0000306684 MDP0000137051 MDP0000311403112,9MDP0000122739 MDP0000122740 MDP0000151428MDP0000283350113,5

MDP0000932292113,8MDP0000410215113,9MDP0000293049115,4MDP0000204234115,5MDP0000718430115,6MDP0000386318 MDP0000266480116,5MDP0000122864117,0MDP0000189394117,1MDP0000142765117,5MDP0000206102117,6MDP0000330776117,7MDP0000225700 MDP0000140388117,8MDP0000181608 MDP0000198495118,5MDP0000483865118,6MDP0000246042119,1MDP0000303501120,0MDP0000052608 MDP0000052605120,6MDP0000137704 MDP0000757476122,1MDP0000272284 MDP0000140294 MDP0000209790MDP0000922614 MDP0000501238122,8

MDP0000302012 MDP0000297862 MDP0000279706128,4MDP0000423881129,3MDP0000249285 MDP0000249275129,5MDP0000220211130,3

chr_15

MDP00002547240,5MDP00002342910,6MDP00008266000,8MDP00006735531,3MDP00002994961,4MDP00002345282,7MDP00001814293,0MDP0000137803 MDP00002483763,2MDP00001734774,4MDP00007259915,0MDP0000185022 MDP00003924855,3MDP00007592995,4MDP00009396335,9MDP00002245926,0MDP00003197266,1MDP0000183562 MDP00001542726,9MDP00002215637,1MDP00002612937,2MDP00001311007,5MDP0000457996 MDP0000695714 MDP0000013331MDP00002800098,0

MDP0000255565 MDP0000236349 MDP00009185668,6MDP0000707539 MDP00005485118,8MDP0000233503 MDP00005601799,0MDP00002582129,1MDP0000364750 MDP00002629909,5MDP0000681724 MDP00001476679,7MDP000024182110,1MDP000024142410,4MDP000016188110,7MDP000016281710,8MDP000028260011,4MDP000032887411,9MDP000023095012,1MDP000014380412,2MDP000054765512,8MDP000023317712,9MDP000019177413,0MDP000016405413,1MDP0000790939 MDP000044449413,3MDP000027825413,5MDP000024767214,0MDP000012317214,6MDP000023531815,0MDP000075336615,3MDP000027714915,7MDP000026660315,8MDP0000222620 MDP0000162904 MDP000066853716,1MDP0000621927 MDP0000645828 MDP000031926316,3MDP0000129547 MDP000021540516,6MDP000030892216,8MDP0000535983 MDP000019111017,6MDP000015006818,1MDP000031080018,4MDP0000220008 MDP000061640218,5MDP000012388818,6MDP000013012319,4MDP000073574720,1MDP000018645220,5MDP0000176288 MDP000013703520,6MDP0000249104 MDP000024910520,7MDP000025651420,8MDP0000195096 MDP000086531321,5MDP000028511021,6MDP000028310621,8MDP000024600623,6MDP000023361424,2MDP000013175924,8MDP000023703927,8MDP000029444428,2MDP000023676828,6MDP000013779228,7MDP0000252150 MDP0000413387 MDP000077757928,9MDP000015254831,9MDP000025767332,0MDP000046775332,2MDP000017746833,1MDP000079887833,4MDP000022487534,3MDP000020503035,5MDP0000204470 MDP000039893136,6MDP0000246150 MDP0000942265 MDP000019774338,2MDP000015293839,1MDP000023987839,3MDP000014103339,7MDP000019716040,3MDP000020834540,7MDP000032491940,9MDP0000289177 MDP0000287577 MDP000012481041,1MDP000031432141,9MDP000028684642,8MDP000029269543,0MDP000044036743,8MDP000093626944,0MDP000025514644,3MDP000032256744,4MDP000056262744,6MDP000023531345,7MDP000028669347,5MDP000028177347,7MDP000013482448,3MDP000045979449,5MDP000024076650,4MDP000069317451,1MDP000029539251,5MDP0000211803 MDP000087101051,6MDP0000369941 MDP000017985151,7

chr_16

MDP00003620330,1MDP0000580186 MDP00006889000,2MDP00002479120,6MDP0000203334 MDP00004699430,8MDP00008427020,9MDP00001425831,5MDP00002081971,6MDP00008929792,0MDP0000145439 MDP00002754122,8MDP00002839753,5MDP00002817774,4MDP0000280003 MDP00009112785,6MDP0000576836 MDP00005758236,1MDP0000159916 MDP0000942526 MDP00002611586,2MDP00001574297,3MDP0000301545 MDP0000206674 MDP00002066767,9MDP00002903748,1MDP00002400278,5MDP00006709599,1MDP0000232050 MDP00001293359,2MDP0000184228 MDP00003209329,5MDP0000551969 MDP00001284649,6MDP0000286574 MDP0000544455 MDP0000120215MDP000025352310,2

MDP000035152610,5MDP0000164967 MDP000027005110,8MDP000050151811,9MDP0000246204 MDP000016025612,1MDP0000271553 MDP000024319412,3MDP000072601212,6MDP000025357612,7MDP000024066313,7MDP000027758215,0MDP0000366022 MDP000089588315,3MDP000086390916,0MDP0000240648 MDP000027718316,5MDP000094526717,0MDP000032156917,1MDP000021241117,3MDP000032802618,0MDP000019237418,4MDP0000214081 MDP000023817318,7MDP0000186131 MDP0000229036 MDP000022609919,6MDP000040440919,9MDP0000290585 MDP0000378203 MDP000013243120,2MDP000013649820,4MDP000032268820,6MDP0000297049 MDP000081771020,7MDP0000641681 MDP000040475421,7MDP0000143216 MDP000075387021,9MDP000016837524,2MDP0000121713 MDP000023007424,7MDP000088599524,9MDP000025253625,3MDP000025129525,7MDP000083982826,1MDP000021249626,5MDP000025186426,8MDP000058283626,9MDP000026080327,1MDP000023959627,3MDP0000184361 MDP000017580927,7MDP0000300536 MDP000029095828,9MDP000020128129,4MDP000015072130,3MDP0000133911 MDP000015072930,4MDP000078001130,9MDP0000193401 MDP0000128410 MDP0000915151MDP000029986031,1

MDP0000159635 MDP0000311467 MDP000021995031,2MDP000080490031,3MDP000042866031,4MDP0000246674 MDP000020877831,7MDP0000873295 MDP0000806350 MDP000023897632,0MDP0000764876 MDP000036151132,1MDP0000219404 MDP0000215774 MDP000014739132,2MDP0000319957 MDP000015353832,4MDP000011874832,8MDP000019840432,9MDP000017762333,1MDP000072114933,5MDP000025712934,2MDP000022920534,3MDP0000248336 MDP0000173145 MDP000019872734,7MDP000024200934,9MDP000026374435,2MDP000030915935,6MDP000052361935,7MDP000086508435,9MDP000027994336,4MDP000031568837,6MDP000059627539,5MDP000040162939,6MDP0000755167 MDP000031888439,7MDP000025739041,4MDP000017435243,6MDP000091758243,8MDP000026260244,0MDP000087090946,7MDP000037079147,2MDP0000310152 MDP000021317947,8MDP0000235201 MDP0000247298 MDP000024730048,9MDP000088958049,1MDP000027078949,4MDP000087052151,0MDP000017790652,4MDP000023174852,9MDP000025318953,2MDP0000617184 MDP0000137451 MDP000010767653,7MDP000055545755,3MDP000026079055,5MDP000012497155,6MDP000029093456,6MDP000070970556,9MDP000041763257,0MDP0000435467 MDP000012053957,4MDP000026612557,5MDP0000216705 MDP0000524809 MDP000073148057,6MDP0000764803 MDP0000311856 MDP000022045857,7MDP0000951949 MDP0000205224 MDP0000201743MDP0000211736 MDP000043179058,0

MDP000047474658,4MDP000029120060,0MDP0000051653 MDP0000466825 MDP000030501762,0MDP0000187925 MDP000073929563,0MDP0000132870 MDP0000123429 MDP0000520807MDP0000272179 MDP000027771163,2

MDP0000204870 MDP0000204871 MDP000029364963,3MDP000055004963,6MDP000065744164,4MDP000016118164,6MDP0000299357 MDP0000260152 MDP0000279599MDP0000784451 MDP000046888165,0

MDP0000145267 MDP000093194065,3MDP000017292265,4MDP000085080265,5

chr_17

MDP00004781530,8MDP0000301846 MDP00002593166,9MDP00007117747,9MDP00006835358,8MDP0000633218 MDP000040114011,2MDP000015271815,7MDP0000159587 MDP000057204715,8MDP000002565016,2MDP000031227418,4MDP000058001018,5MDP0000188907 MDP0000288901 MDP000018994118,6MDP0000712620 MDP0000191048 MDP000081053918,7MDP000071262318,8MDP0000527355 MDP0000701985 MDP0000268507MDP0000893993 MDP0000893994 MDP000021854918,9

MDP000030167719,5MDP000025779719,6MDP000094008620,7MDP000012477022,3MDP000013646623,1MDP000072349724,3MDP0000321745 MDP000025195624,4MDP0000262827 MDP000013074824,8MDP000060213925,0MDP0000288378 MDP000075625425,2MDP0000122747 MDP0000197219 MDP000089085426,3MDP0000233483 MDP000019370026,8MDP000014670326,9MDP0000237202 MDP0000128157 MDP000072757027,0MDP000045518027,1MDP0000933900 MDP000089703627,7MDP000029468228,0MDP0000406270 MDP000028073028,2MDP000067121028,7MDP000030882728,8MDP000032104930,4MDP000016879030,5MDP0000151262 MDP000061266030,9MDP0000121609 MDP0000761338 MDP000013959231,0MDP0000705786 MDP0000882983 MDP000027282331,4MDP000083629331,5MDP000013665231,6MDP0000392668 MDP0000688878 MDP0000291838MDP0000138340 MDP0000200646 MDP000027919731,7

MDP000044082931,8MDP0000204944 MDP000030027131,9MDP0000151717 MDP000070324432,0MDP0000151095 MDP000025963333,3MDP000031287433,7MDP000023022833,8MDP000031907233,9MDP000066882834,2MDP0000151159 MDP000021746534,5MDP000025848234,6MDP0000250651 MDP000013908334,7MDP000023949635,5MDP000023464135,7MDP000014641535,8MDP000023621036,1MDP000028595536,5MDP000025962037,6MDP000013665439,7MDP0000274127 MDP0000198407 MDP000068295340,0MDP0000252300 MDP000057361741,1MDP000015773741,4MDP000031970041,9MDP000012805842,2MDP000091749642,3MDP000013962842,4MDP000019579844,7MDP000011918444,8MDP000031012845,2MDP000025564246,5MDP000070524446,6MDP000005563947,3MDP000013367147,7MDP000014416749,9MDP000017000550,0MDP000027944650,1MDP000037736451,3MDP000013236052,1MDP000062156952,5MDP000022537652,8MDP0000446783 MDP000014700953,4MDP000016572954,1MDP0000772420 MDP000043169654,5MDP0000265383 MDP000027973355,8MDP000032275556,2MDP0000249604 MDP000087072756,4MDP000025630656,5MDP000046221456,9MDP000017612357,1MDP0000919323 MDP000061411558,0MDP0000320566 MDP000014636058,3MDP0000229827 MDP0000299112 MDP0000157124MDP0000299114 MDP0000226941 MDP0000536969MDP0000131899 MDP0000254030 MDP0000306013

58,4

MDP0000854241 MDP000085424258,5MDP000050324658,6MDP000050324858,7MDP000023894259,0MDP000013333459,1MDP000050806859,3MDP000040885359,4MDP000030055659,5MDP000068460559,8MDP000024625860,5MDP0000296814 MDP000086661160,6MDP000024898160,8MDP0000144597 MDP0000462145 MDP000024959261,2MDP000020027261,3MDP0000262710 MDP000015522661,7MDP000012565862,1MDP000015644062,8MDP000021389262,9MDP000021707363,9MDP0000127054 MDP000029764664,4MDP000022607464,8MDP000068916264,9MDP000026334965,0MDP000019185165,1MDP000013617765,3MDP000029357866,5MDP0000863082 MDP000027781566,6MDP000047825266,7MDP000077157367,0MDP0000416305 MDP0000156509 MDP0000214162MDP000041630767,5

MDP0000165031 MDP0000178570 MDP0000656929MDP0000657536 MDP000065753767,6

MDP000029656769,1MDP0000318862 MDP000015512469,4MDP0000188700 MDP000020832269,5MDP0000219647 MDP0000191607 MDP000046839170,2MDP000085403970,3MDP0000242436 MDP0000277370 MDP0000128265MDP000029452671,0

MDP000027737171,1MDP000025423171,3

chr_1

MDP00003182161,2MDP00005024401,4MDP00006156842,8MDP00005248762,9MDP00001503823,0MDP00002648093,2MDP00003082243,6MDP00002934563,7MDP0000277672 MDP00001298603,8MDP00001658024,0MDP00005138804,3MDP00003264934,8MDP00002147144,9MDP0000185723 MDP00006377375,0MDP00002996585,3MDP0000644549 MDP0000321792 MDP00001649665,8MDP0000891962 MDP0000891965 MDP0000214625MDP0000201387 MDP00002760345,9MDP0000305297 MDP00001966276,0MDP0000288876 MDP0000306580 MDP00002151826,3MDP00003159596,4MDP00006963316,6MDP00001570356,9MDP0000136806 MDP00001656567,5MDP00002705737,6MDP00001720657,7MDP00004308707,8MDP00004519048,2MDP00001989768,4MDP000014519310,5MDP0000239167 MDP000025157910,7MDP000025102011,0MDP000037634711,1MDP0000123081 MDP0000219155 MDP0000438458MDP0000610753 MDP000066238711,2

MDP000014841411,3MDP000042071511,6MDP000018882712,0MDP000016910212,2MDP000017466412,3MDP000026406112,4MDP000024229712,6MDP000065241312,7MDP0000131126 MDP000022197712,8MDP000021250213,8MDP000072376214,0MDP000012450914,1MDP0000707034 MDP000060180014,3MDP000031098714,4MDP0000874578 MDP000040621714,5MDP000028621014,6MDP000041770415,6MDP000025289915,7MDP000018088215,8MDP0000452677 MDP000043564415,9MDP0000548003 MDP0000548004 MDP0000552242MDP000028855416,0

MDP0000200513 MDP0000156075 MDP0000277173MDP000021721916,1

MDP0000251898 MDP000021722016,2MDP000013336716,8MDP000031822917,2MDP000058531517,9MDP000021198718,0MDP0000704216 MDP000088663718,3MDP000051548918,4MDP000033758518,5MDP000013565219,3MDP000014451619,4MDP000016887119,5MDP000021605319,6MDP0000212766 MDP0000128793 MDP000053742520,0MDP0000692632 MDP000024847020,1MDP000019944221,7MDP0000292963 MDP000029296522,7MDP000027667623,0MDP000026331323,8MDP000013907324,2MDP000025048725,0MDP000058085825,2MDP0000232805 MDP000032794025,3MDP0000545023 MDP000018394125,4MDP0000181133 MDP000022538226,6MDP000087685826,8MDP0000224397 MDP0000710349 MDP000020722027,5MDP000012819027,6MDP000022339727,8MDP000012626728,4MDP000047092828,5MDP000086153529,2MDP0000380194 MDP000029806929,3MDP0000632145 MDP0000259172 MDP0000295032MDP0000198082 MDP000089451129,4

MDP000049418129,6MDP000070437729,7MDP000058529031,0MDP000030307832,4MDP000061067834,9MDP000029879335,0MDP000028343235,4MDP0000183156 MDP000015526735,5MDP000028658935,7MDP000015576835,9MDP000028427436,2MDP0000184294 MDP000031593836,3MDP0000160578 MDP0000215889 MDP000025280236,4MDP0000146806 MDP0000378862 MDP000056338536,5MDP0000172708 MDP000030686236,6MDP000067999336,8MDP0000249561 MDP000093244937,3MDP000026587537,8MDP000028123138,8MDP000023009239,8MDP000080147639,9MDP000091429740,1MDP000025133240,3MDP000081318640,5MDP000024494640,6MDP0000600192 MDP0000818140 MDP000025188340,7MDP0000135820 MDP000024814840,9MDP0000576390 MDP000066886941,0MDP000020379041,1MDP000022496945,6MDP000025422747,1MDP000068366047,5MDP000012462647,8MDP000084625747,9MDP000042019248,1MDP000021558748,4MDP000012567348,9MDP000012846349,2MDP000013732552,9MDP000018394853,0MDP000052394253,6MDP0000333317 MDP0000269483 MDP000066196054,4MDP0000801540 MDP000024753355,8MDP0000452189 MDP0000251256 MDP0000287234MDP000025250855,9

MDP000024940056,3MDP000032108856,7MDP000031476558,8MDP000014967658,9MDP000013694059,2MDP0000319630 MDP000023097261,9MDP000013916562,7MDP000063916764,0MDP000018903365,6MDP000016201967,2MDP000031661267,3MDP000051792468,1MDP000013933468,2MDP000023584169,0MDP000028152569,8MDP000075354769,9MDP0000412658 MDP000021155670,0MDP000031550070,4MDP000022529970,5MDP0000224062 MDP000019856171,6MDP0000204182 MDP000027498871,7MDP0000152045 MDP000023340771,8MDP0000180785 MDP000027067772,7MDP000024806373,2MDP000025528473,3MDP000089791973,4MDP0000136650 MDP0000156783 MDP000024938473,6MDP000064116774,0MDP0000893802 MDP0000852165 MDP000089870174,1MDP000030918174,4MDP000024900674,6MDP000092342675,9MDP000014595376,1MDP000066594578,0MDP0000300532 MDP000017493080,2MDP0000928314 MDP000015163881,0MDP000031208981,1MDP000029657683,7MDP000027321184,8MDP0000299506 MDP0000203952 MDP0000398467MDP0000422279 MDP000020283184,9

MDP0000129902 MDP000080352785,1MDP0000233590 MDP000042455385,4MDP0000170391 MDP000019868686,2MDP000023266587,3MDP000087088187,4MDP000093633188,7MDP0000274938 MDP000015329788,9MDP0000716997 MDP000018727989,0MDP000077695889,2MDP000043767689,7MDP000030597690,7MDP000012453690,8MDP0000196867 MDP0000173284 MDP000020408491,4MDP000028888691,9MDP000022972592,2MDP0000132456 MDP000018060592,4MDP000023253393,2MDP000072629593,5MDP000012387893,6MDP000022627995,0MDP000012677099,9MDP0000237091100,2MDP0000620349 MDP0000420893100,8MDP0000285057101,4

chr_2

MDP00002610670,6MDP00004880071,5MDP00005259332,3MDP00004330942,7MDP0000151924 MDP00001515112,8MDP00004309453,4MDP00002077224,2MDP00005804114,5MDP00001886985,6MDP00001299415,8MDP00004663316,4MDP00001350597,2MDP00002981668,0MDP00008257128,1MDP00001400468,3MDP0000119547 MDP00001370758,5MDP0000193347 MDP0000304484 MDP00002361389,1MDP000016134710,3MDP0000431358 MDP000064833810,4MDP000019050411,6MDP0000293847 MDP000048526811,7MDP0000166951 MDP000060284111,8MDP0000120157 MDP000012015811,9MDP000031783112,0MDP000022849412,1MDP000028478912,4MDP0000127732 MDP0000146449 MDP0000267678MDP0000921016 MDP000026768112,6

MDP0000514115 MDP000050780513,0MDP000031346013,5MDP000022211414,0MDP000030139914,1MDP000016402314,4MDP000018745414,5MDP000031360517,2MDP0000240081 MDP000016782417,4MDP000060101717,6MDP000029294917,7MDP000020289817,8MDP0000137531 MDP000069720619,6MDP000019411020,3MDP0000505274 MDP0000192448 MDP000015014020,5MDP000065269221,0MDP000032906321,5MDP000013528221,6MDP000082807722,1MDP000083012922,3MDP000015554322,4MDP000090415822,7MDP000011936423,2MDP000029671623,4MDP000027630723,8MDP0000499023 MDP000051615924,8MDP0000196802 MDP000026319225,7MDP000022132226,1MDP000013148126,2MDP000032012726,3MDP000031980627,1MDP0000148190 MDP000013485628,4MDP0000198741 MDP0000209964 MDP0000931131MDP000025698928,8MDP000028161330,1MDP000059529530,7MDP000075950431,9MDP000013079732,0MDP0000188581 MDP000023981032,7MDP000013363632,8MDP000026804533,6MDP000015538936,2MDP000013439736,5MDP000030443038,1MDP000014196139,5MDP000025770739,6MDP000015458940,0MDP0000187446 MDP000066328140,4MDP000025112541,9MDP0000265073 MDP0000132627 MDP000072998443,7MDP0000299944 MDP000020452543,8MDP000025450444,2MDP000094421044,5MDP000016653546,8MDP000016944247,4MDP000020247347,9MDP000002978348,4MDP000023425148,9MDP000080094549,2MDP000021700549,3MDP0000571255 MDP0000115697 MDP000013279449,5MDP000024742950,5MDP000031386352,2MDP000024633155,8MDP0000946614 MDP000012586255,9MDP0000146743 MDP000093688656,4MDP000022744256,6MDP000018034356,7MDP000019727158,8MDP0000744693 MDP000024311358,9MDP000028962659,0MDP000026327259,6MDP000018470459,9MDP000014411360,4MDP000031594761,1MDP0000179728 MDP0000212581 MDP0000593587MDP000032078962,2

MDP000075394663,2MDP000015383163,5MDP000020561763,9MDP0000132162 MDP000026207864,3MDP000029544064,9MDP000058190365,1MDP000015596565,4MDP000019676266,1MDP000086841966,9MDP000026203267,0MDP0000306058 MDP000012882768,0MDP000065140968,1MDP000032471869,4MDP000013586069,5MDP000013493670,0MDP000027339070,1MDP000057933270,2MDP000028156270,3MDP0000663949 MDP000079075070,4MDP000070860972,6MDP000020176973,6MDP0000273274 MDP0000481866 MDP0000273276MDP000024285474,0

MDP0000300393 MDP000021535174,6MDP000022204574,7MDP0000907178 MDP000017473474,8MDP000019793976,7MDP000014868076,8MDP0000270013 MDP0000264703 MDP000018462077,7MDP000029840877,8MDP0000289686 MDP000029106177,9MDP000030702078,1MDP000061707778,6MDP000012978779,0MDP000029579479,4MDP0000123466 MDP0000123668 MDP000013885380,1MDP000049841980,3MDP000044387680,4MDP0000247441 MDP0000202829 MDP000027425780,5MDP000056849881,6MDP000016252382,0MDP000025420382,1MDP0000196922 MDP0000294145 MDP0000200484MDP000079870582,4

MDP000079870782,5MDP000026624582,6MDP0000848905 MDP0000679280 MDP0000257135MDP000014779482,7

MDP000029448982,8MDP0000215772 MDP000031517683,0MDP000043768083,2MDP000025305583,8MDP000012452284,0

chr_3

MDP00002637560,3MDP00004163880,4MDP00002097051,0MDP00002621921,4MDP00005289841,8MDP00004305462,7MDP0000296410 MDP00001396092,8MDP00001337622,9MDP0000619501 MDP00005352473,0MDP0000258512 MDP00001933833,1MDP0000702868 MDP0000655939 MDP00001482213,2MDP00001564786,0MDP0000262916 MDP0000628479 MDP00006284846,3MDP00001892696,4MDP00005452746,6MDP00001658806,8MDP0000247372 MDP00005216628,1MDP0000228304 MDP00008280558,3MDP0000791464 MDP0000923579 MDP0000309801MDP00002408408,6

MDP00001495919,4MDP000029203111,0MDP000028730211,1MDP000015476412,2MDP000084900612,3MDP000049020014,1MDP000027771014,2MDP000025058414,4MDP000030238515,8MDP000044420516,1MDP000021193416,8MDP0000454482 MDP0000834641 MDP000083464217,0MDP000039876517,2MDP000026412417,6MDP000083465617,7MDP000031669418,0MDP000084372218,4MDP0000261492 MDP000019130420,2MDP0000291384 MDP000075039220,7MDP000020031921,9MDP0000256806 MDP000023154222,3MDP000080292423,6MDP0000444224 MDP000051009624,3MDP000025067225,5MDP0000201047 MDP000063544826,8MDP000016962127,2MDP000078858127,3MDP000031923528,3MDP0000310803 MDP000075242830,8MDP0000422442 MDP0000243428 MDP000079938730,9MDP000020784831,0MDP000041026431,5MDP000022200431,6MDP000021537131,9MDP000020809832,2MDP0000242087 MDP000080912532,3MDP000021590433,4MDP000090792934,4MDP0000135205 MDP000065045634,5MDP000012266534,7MDP000028457434,8MDP000017839834,9MDP000060354635,5MDP000063031935,6MDP0000456277 MDP000070670235,7MDP000075763638,2MDP000050394038,7MDP000043633840,6MDP000015386641,3MDP000021926941,5MDP0000708692 MDP000020809041,9MDP000089614042,7MDP000051832142,8MDP000027883943,1MDP0000256347 MDP000080030043,2MDP000062776543,4MDP0000627768 MDP0000858585 MDP000072931343,5MDP0000654033 MDP000003935743,6MDP000003935943,7MDP0000672345 MDP000019457043,9MDP000032183944,0MDP000029871144,4MDP000024541345,7MDP0000171707 MDP0000171708 MDP0000248589MDP000020535845,8

MDP0000212925 MDP000012929846,1MDP0000900024 MDP000085949246,6MDP000030027446,7MDP000012876146,8MDP0000179031 MDP000003217147,1MDP000085327447,3MDP000082884347,4MDP0000123025 MDP000052761547,6MDP000024227747,7MDP000013924847,9MDP0000734600 MDP000013667448,4MDP000026061749,2MDP000021941549,5MDP0000264666 MDP000023684749,6MDP0000923670 MDP000042354449,7MDP000031239749,8MDP000029733149,9MDP000005693550,2MDP000026717850,5MDP0000756894 MDP000020269052,5MDP000030809552,9MDP000014791353,0MDP0000363509 MDP000029558953,4MDP0000295593 MDP000019221053,5MDP0000782085 MDP000015498553,6MDP000023199353,7MDP0000265206 MDP000016834554,3MDP000032227954,4MDP0000692845 MDP000052947155,9MDP000029454356,1MDP0000194938 MDP000027896656,2MDP000037918656,5MDP000030191356,6MDP0000144203 MDP0000200038 MDP000019832756,7MDP000032140956,8MDP0000312169 MDP000058026356,9MDP0000287973 MDP000012531757,0MDP0000422558 MDP000030744257,5MDP000015187757,6

chr_4

MDP0000250856 MDP00002324170,8MDP00002332881,0MDP00008953411,1MDP00000889531,3MDP00009246121,5MDP00001950131,9MDP0000864349 MDP00007893902,1MDP00003067672,6MDP00002007373,1MDP0000202902 MDP00002058923,8MDP00003016663,9MDP00003706115,1MDP0000182058 MDP0000165000 MDP00003094515,2MDP00003019997,0MDP00002857807,1MDP0000243196 MDP0000320264 MDP0000174748MDP00003232917,2

MDP0000295452 MDP00001835407,9MDP00003167058,5MDP00007915539,0MDP00002556969,2MDP00001459919,8MDP0000173636 MDP00001736379,9MDP000080826210,5MDP0000569022 MDP000022415011,4MDP0000864970 MDP0000472095 MDP0000666752MDP000031395611,5

MDP000066720112,0MDP0000276278 MDP000017315112,3MDP0000729320 MDP000072932112,5MDP0000805422 MDP000018095012,6MDP0000256492 MDP0000251135 MDP000013970913,4MDP000030348514,0MDP0000796828 MDP000069551214,1MDP000030411314,6MDP000025008015,2MDP000037263215,4MDP000016131715,8MDP000026402415,9MDP000031939616,1MDP000011881016,3MDP0000601491 MDP0000235175 MDP0000417927MDP000041792916,4MDP0000229007 MDP0000656152 MDP0000656154MDP0000153000 MDP000027190316,5

MDP0000120467 MDP000069633316,6MDP0000204678 MDP0000875642 MDP0000293051MDP0000293052 MDP000031604616,7

MDP0000247490 MDP000032244017,1MDP000038646017,3MDP000031997917,6MDP000092921317,7MDP000089205717,9MDP000049328418,6MDP0000183226 MDP0000181583 MDP0000179718MDP000023407322,4MDP000077848622,7MDP0000242552 MDP000012212223,6MDP000046043024,7MDP000019984025,2MDP000014703025,3MDP000016553426,1MDP0000725651 MDP000068999126,3MDP0000280921 MDP000020948326,5MDP000051585528,2MDP000042826528,3MDP000011981129,5MDP000021737329,6MDP000081108130,5MDP000030709433,2MDP0000234323 MDP000067312833,3MDP000040108633,8MDP000024362833,9MDP0000496268 MDP0000310904 MDP000023660534,9MDP000023749935,1MDP0000237498 MDP0000235118 MDP0000275309MDP0000171866 MDP000032439835,2

MDP000018370035,3MDP000018533335,4MDP000072327736,4MDP000077658336,7MDP000015924036,9MDP0000375330 MDP0000204319 MDP0000164293MDP0000204521 MDP000056902637,1

MDP0000223243 MDP0000181169 MDP000049284537,2MDP0000548790 MDP000018601137,4MDP0000132805 MDP000085876337,8MDP000081258638,0MDP000019316738,2MDP000089576839,0MDP0000514358 MDP000029149939,1MDP000021829239,6MDP0000276665 MDP000025628039,7MDP000015061039,8MDP0000391619 MDP000019640440,7MDP0000311020 MDP000021935141,1MDP0000300382 MDP000067598241,5MDP000038151441,7MDP000083713942,8MDP000043405943,4MDP000046821745,0MDP000012284746,8MDP000016442946,9MDP0000517601 MDP000021271247,8MDP000026751348,8MDP000013773348,9MDP000025904449,1MDP000095005749,4MDP0000137816 MDP000024297949,5MDP0000800550 MDP000022477949,7MDP000075021749,9MDP000026829650,4MDP000013618050,7MDP0000299959 MDP000029896550,8MDP000084287751,0MDP0000139343 MDP000025084951,1MDP000022430251,4MDP0000219737 MDP0000393617 MDP000019591651,5MDP000027685951,8MDP000021635752,6MDP000052865852,7MDP000027584454,2MDP0000174149 MDP000015507354,8MDP000073346855,0MDP000027831356,3MDP000012640457,7MDP0000233925 MDP0000233926 MDP000027877058,1MDP000027889258,5MDP000015889559,8MDP000065406859,9MDP000094651560,2MDP000087389364,6MDP000018149065,5MDP000091692067,2MDP000030675467,4MDP000024856768,0MDP0000124584 MDP000012458568,7MDP000058940368,8MDP000020184469,2MDP0000939384 MDP000081854269,4MDP000084391370,8MDP000064497970,9MDP000022894272,1MDP000061102272,4MDP000047554972,6MDP000025795374,1MDP0000229843 MDP000031880174,7MDP000025767475,6MDP000094342676,4

chr_5

MDP00003093311,1MDP00002873001,9MDP0000330698 MDP00003213382,0MDP0000233260 MDP00001427282,1MDP00007023552,2MDP0000191344 MDP00001672083,1MDP00001639304,1MDP00004518274,2MDP0000299637 MDP00002364384,3MDP00002092834,4MDP00007025574,5MDP00006648414,7MDP00004075725,1MDP0000060934 MDP00002829455,2MDP00002331645,7MDP0000563404 MDP00006169495,8MDP00002124655,9MDP00005467926,1MDP00002513396,5MDP00004192976,6MDP00001855538,2MDP00001394858,3MDP00006215458,4MDP0000911336 MDP00007727318,9MDP00001194469,4MDP000002916810,4MDP000079491311,2MDP000021481112,5MDP000020389513,5MDP000012166914,5MDP000020713414,7MDP000025950214,8MDP0000300492 MDP000016834114,9MDP000016536415,3MDP0000127230 MDP000023471416,3MDP000042332916,9MDP0000248311 MDP000024831217,2MDP000020806917,3MDP0000240641 MDP0000360447 MDP000024064319,1MDP000007167719,9MDP000022760620,4MDP000076201921,0MDP000049127122,5MDP000013650022,6MDP000090442123,7MDP000084319123,8MDP000078893426,7MDP000025025427,3MDP000085025529,4MDP000051285029,9MDP000087325830,0MDP000043572230,3MDP000083706531,7MDP0000198054 MDP000015505731,8MDP000013024432,7MDP000026039333,0MDP000024660833,1MDP000013303733,3MDP000013995034,0MDP0000273365 MDP000027584035,4MDP000017296335,6MDP000026892836,3MDP0000710285 MDP000024255436,7MDP000072951436,9MDP000016060037,0MDP000045170537,2MDP0000762302 MDP000024106337,4MDP0000263768 MDP000083666139,0MDP000031238239,2MDP000013126741,8MDP0000718765 MDP000057374642,9MDP000013222643,0MDP000031919443,1MDP000067055943,3MDP0000135108 MDP000022939144,9MDP000019353545,4MDP000022358045,5MDP000022867145,7MDP000014098045,8MDP000051368545,9MDP0000148461 MDP000020704846,6MDP000026482747,0MDP000021526947,1MDP0000137872 MDP000030071247,9MDP000030826148,0MDP000073850548,1MDP0000239877 MDP0000313569 MDP0000550728MDP0000202881 MDP000019809448,2

MDP000030187148,3MDP0000193127 MDP0000193128 MDP000019312948,9MDP000091172449,0MDP000028867049,9MDP000077283550,0MDP0000575443 MDP000019048950,3MDP0000461555 MDP000028871551,0MDP000048938451,2MDP000030758251,3MDP000057422251,4MDP000021802051,6MDP000014320851,7MDP000023484951,8MDP0000189019 MDP000091731551,9MDP0000155743 MDP000015574652,0MDP000016677953,3MDP0000235213 MDP0000246482 MDP000015394953,5MDP000087933753,6MDP000050915753,7MDP000024232754,2MDP0000230839 MDP000095171455,5MDP000020023155,7MDP000038778759,0MDP000037518159,7MDP000059520059,8

chr_6

MDP00002822291,2MDP0000268306 MDP00001675971,4MDP00001335291,5MDP0000280559 MDP00004796522,4MDP0000143749 MDP00007686672,5MDP00001400662,9MDP00008972423,0MDP0000615769 MDP00002531293,6MDP00001423983,7MDP00007164964,1MDP0000012534 MDP00008644424,2MDP00000125414,3MDP00002619414,4MDP00002144724,5MDP00001741684,6MDP0000279287 MDP0000178268 MDP00001693114,7MDP0000448747 MDP00001645296,4MDP0000299504 MDP0000138811 MDP00003780417,5MDP00002540528,1MDP00004112748,2MDP00007726338,8MDP000023165410,4MDP000018655811,5MDP0000218227 MDP000014696911,6MDP0000718066 MDP000068193613,9MDP000013689414,5MDP000092369014,6MDP000012014714,7MDP000025799515,5MDP000032052415,7MDP000025675916,5MDP000029964816,6MDP000021510617,4MDP0000283197 MDP000061165317,6MDP0000306498 MDP0000244964 MDP0000299884MDP0000244965 MDP000020444917,7MDP000089489517,8MDP0000259085 MDP000031694317,9MDP000066812218,0MDP0000289945 MDP0000241771 MDP000031910718,1MDP000030405919,0MDP000012712319,4MDP000065840919,5MDP0000523205 MDP000026435119,8MDP000042527020,0MDP000029399620,1MDP000077726020,2MDP0000156057 MDP000013598221,2MDP000016886121,9MDP000070875822,1MDP000021660522,6MDP0000258167 MDP000025673023,1MDP0000297071 MDP000020077323,7MDP0000128879 MDP0000174791 MDP000023337023,8MDP000018520924,4MDP000025619524,5MDP000019390224,7MDP000019126725,8MDP0000161897 MDP000012777127,1MDP000085189328,0MDP0000498999 MDP000022871328,5MDP000043954032,3MDP000069560432,5MDP000017544632,8MDP000078865532,9MDP000018470635,8MDP000014885737,3MDP000078396640,1MDP000022832840,4MDP000011903140,5MDP0000909869 MDP000058761440,6MDP000055495041,0MDP000085793741,1MDP000017380942,1MDP000070588942,2MDP000024789642,4MDP0000435100 MDP000012324842,6MDP0000218810 MDP000025761444,2MDP000014295745,6MDP000013348547,6MDP000013194547,7MDP000019420648,2MDP0000194603 MDP000064510548,4MDP0000575835 MDP0000311190 MDP000021556450,9MDP0000294573 MDP0000231843 MDP0000231845MDP000083518051,0MDP000030304151,1MDP0000126141 MDP000024994751,2MDP000074547551,7MDP0000552625 MDP000027550951,8MDP000082999851,9MDP000053600452,7MDP000030741053,1MDP000024320554,4MDP000076289554,6MDP000022759854,7MDP000013080254,8MDP000021676557,1MDP000056316557,6MDP000022649758,6MDP0000280968 MDP000077406658,8MDP000017273659,2MDP000027472359,8MDP0000138052 MDP000049379560,4MDP000024144760,7MDP000078665061,2MDP000087565461,3MDP000019101761,6

chr_7

MDP0000839414 MDP00001224780,5MDP0000134342 MDP00002406130,9MDP0000306022 MDP00001511641,0MDP00002641731,4MDP00002411261,5MDP00001476351,8MDP0000282828 MDP00003008202,3MDP00002201682,7MDP0000141335 MDP00002959022,8MDP00005219343,3MDP00005768893,8MDP00002058234,2MDP00001352304,7MDP00002275775,1MDP00002003556,1MDP00008758386,9MDP00002683207,2MDP00001753757,5MDP00002387737,7MDP0000441757 MDP00006387867,9MDP00004243988,1MDP0000225501 MDP00009108578,2MDP0000231298 MDP0000252854 MDP00002528558,4MDP00004406548,5MDP00005284298,7MDP00003217009,3MDP00004642769,6MDP00001866559,7MDP00002427509,8MDP000028553510,4MDP000093065513,6MDP000078716813,7MDP000089110813,8MDP0000190950 MDP000015620714,1MDP000073720214,4MDP000024446914,7MDP000029632414,8MDP000025970614,9MDP0000253285 MDP000012381615,0MDP000018329915,1MDP000038153115,2MDP0000181479 MDP000021284117,1MDP000026970117,5MDP0000159571 MDP000022883817,6MDP0000263961 MDP0000307516 MDP000023640417,7MDP000029652018,1MDP000024337518,2MDP000031178818,4MDP000042594219,2MDP0000299555 MDP000048054719,7MDP000040574820,3MDP000014663020,4MDP000031918720,8MDP000072198721,4MDP0000421809 MDP000019507222,8MDP000031895123,0MDP000014163523,5MDP000017692723,9MDP0000249929 MDP000049607124,6MDP000026020324,8MDP0000498407 MDP000059059624,9MDP000027624126,6MDP000014582528,1MDP000029249228,4MDP0000140166 MDP000020082228,6MDP000015282129,9MDP0000626334 MDP000043500730,6MDP000012988230,8MDP000025856231,1MDP000024598831,7MDP000024213531,8MDP0000649866 MDP000022508832,1MDP000070173432,2MDP0000123894 MDP000012389332,4MDP0000174414 MDP000032073932,6MDP0000713910 MDP000052381232,7MDP000051699133,4MDP0000178787 MDP000023016933,6MDP0000269843 MDP000058062934,6MDP000013115835,6MDP0000308745 MDP000038545136,4MDP000075373637,7MDP000024165038,7MDP0000431701 MDP0000193584 MDP000027870739,0MDP000053688139,3MDP000013596641,8MDP000073466141,9MDP000022808442,1MDP000017115442,2MDP000028726644,3MDP000046242944,4MDP000069016844,7MDP000026040444,8MDP000043766445,1MDP000073747245,4MDP0000184157 MDP000024225546,3MDP000071655146,5MDP000032028346,8MDP0000739406 MDP000027668847,8MDP0000215926 MDP0000631089 MDP000013575847,9MDP0000199273 MDP000062998548,1MDP000018879448,9MDP0000498524 MDP0000200450 MDP0000290801MDP000030612149,0

MDP0000553484 MDP0000215525 MDP0000735095MDP000089950849,1

MDP000076976449,2MDP000027439049,7MDP0000548763 MDP000028422049,8MDP000023901152,3MDP000031494252,4MDP000054371853,0MDP000032056353,5MDP0000278387 MDP0000477771 MDP000030944553,6MDP000019810853,7MDP000013733053,8MDP000022807054,1MDP000028735055,1MDP000025897956,5MDP000029782156,6MDP000028664357,4MDP0000139057 MDP000048332159,1MDP000031799359,7MDP000045402760,8MDP000031347661,4MDP000012320061,8MDP000031974662,5MDP000028429763,1MDP000083616563,2MDP000025929463,6MDP000025929663,7MDP000052719063,8MDP0000166457 MDP000030083664,7MDP0000619822 MDP000038853764,8MDP0000211931 MDP000027764365,0MDP0000752882 MDP0000463584 MDP000079365665,2MDP0000552871 MDP000021246166,3MDP0000950422 MDP000025936066,4MDP000068247166,6MDP0000749719 MDP000081629767,1MDP000017293367,3MDP000067451467,8MDP0000925348 MDP000018860469,3MDP0000273450 MDP0000314729 MDP000015048569,5MDP000021948269,6MDP0000188229 MDP0000221319 MDP0000273242MDP0000162976 MDP000020086770,8

MDP000045381370,9MDP000016877371,1MDP0000060059 MDP000006005671,4MDP000045647671,5MDP000017878271,7MDP000025927973,1MDP0000491658 MDP000074710574,6MDP0000303333 MDP0000442215 MDP000056726474,9MDP0000445110 MDP000031576475,0MDP0000192806 MDP000019395375,3MDP0000483351 MDP000012026975,5MDP0000274003 MDP000017016275,8MDP000075653675,9MDP000018790976,6MDP000024009476,7MDP000070637978,5MDP0000738631 MDP000017971979,0MDP0000275938 MDP000029860179,2MDP000024779180,3MDP0000191559 MDP000015152180,5MDP000031790780,6MDP0000466557 MDP0000428573 MDP000028702981,3MDP0000564884 MDP000021288181,8MDP000016492381,9MDP0000929655 MDP000048520582,0MDP000027756082,7MDP0000388002 MDP0000308015 MDP000026313783,1MDP000029818284,0MDP000085924684,3MDP000017855484,7MDP000011923085,3

chr_8

MDP00005279950,7MDP0000247734 MDP00002686521,1MDP00003093821,3MDP0000154734 MDP0000599569 MDP00001234671,7MDP00002641871,9MDP00002961232,0MDP0000399538 MDP0000417953 MDP00008957502,1MDP00002816892,3MDP0000288010 MDP0000285734 MDP00001286792,7MDP00003750392,9MDP0000283867 MDP0000256522 MDP00002388813,1MDP0000225620 MDP00006635643,6MDP00001827223,7MDP0000258005 MDP00005581794,3MDP0000231545 MDP00007492875,0MDP00008644266,4MDP0000250518 MDP00005188857,0MDP0000320993 MDP0000297698 MDP0000201555MDP0000482731 MDP0000186581 MDP00002863227,1

MDP00004525597,2MDP00003206917,6MDP00007307387,7MDP0000432497 MDP00005745548,1MDP00004521638,4MDP00002767658,5MDP0000191788 MDP0000276536 MDP00002425968,8MDP00001791458,9MDP00001965549,0MDP0000679320 MDP0000230835 MDP0000176250MDP0000230836 MDP00003220919,9MDP0000592879 MDP0000280885 MDP0000586116MDP0000261103 MDP0000280886 MDP000027861910,0

MDP000022111410,2MDP0000450991 MDP000045208310,8MDP0000366019 MDP0000289858 MDP000060548211,0MDP0000189308 MDP000013273811,1MDP0000143531 MDP000022385111,3MDP000024553811,6MDP000040775511,9MDP0000126997 MDP000022313713,1MDP000015358913,3MDP0000152089 MDP000018765714,3MDP000022387914,4MDP0000642867 MDP0000278157 MDP0000703981MDP000032802514,5

MDP000056459216,2MDP000036187616,7MDP000019832018,2MDP000024353918,3MDP000014101818,6MDP0000290494 MDP000019815218,8MDP000054905618,9MDP0000561662 MDP000013139719,2MDP0000244701 MDP000092355919,4MDP000019635819,5MDP000072598419,6MDP000045311419,7MDP000041393321,6MDP000031364321,7MDP0000190889 MDP000018617521,8MDP000060392622,8MDP0000670267 MDP000067026823,2MDP000026195923,3MDP0000256105 MDP000025807823,5MDP0000267341 MDP0000708928 MDP000025022323,6MDP000012467223,7MDP000059938823,9MDP000090444524,3MDP000041890024,4MDP0000587103 MDP000028914924,8MDP0000279292 MDP000029991525,3MDP000016497725,4MDP000086665525,7MDP000026985925,8MDP0000176595 MDP0000156988 MDP0000120322MDP0000322379 MDP000087948026,0

MDP000018328326,1MDP000018366027,0MDP0000292218 MDP000019439227,2MDP000042613827,3MDP0000251626 MDP000031990627,4MDP000025465027,8MDP000022490728,2MDP0000128461 MDP000083295228,3MDP000088855328,9MDP0000223496 MDP000050524729,0MDP000031097629,2MDP0000814694 MDP000027267129,5MDP0000271370 MDP0000140678 MDP000087366729,7MDP0000167035 MDP000032425930,1MDP000018332631,7MDP0000231284 MDP000023128532,3MDP000022728734,7MDP000024298034,8MDP000024173635,0MDP0000034165 MDP000006086935,1MDP000015854435,7MDP000022928035,9MDP000050682536,0MDP0000617956 MDP000073350636,1MDP000054512236,2MDP000078264236,5MDP0000187518 MDP000076774336,6MDP000020943237,0MDP0000394374 MDP0000245843 MDP000022657138,1MDP000075427538,2MDP000083224638,9MDP000024618439,0MDP000025811639,2MDP000064682339,4MDP000068666139,8MDP000068666639,9MDP000057574040,0MDP0000121041 MDP000031181540,3MDP0000139953 MDP0000236911 MDP000027064540,7MDP0000652631 MDP000012593941,2MDP000028024041,5MDP000006075341,8MDP0000273574 MDP000042352942,4MDP0000315574 MDP000079637942,5MDP0000291070 MDP000017040244,1MDP000040358044,8MDP0000168682 MDP000016868345,1MDP000024581345,3MDP000061120445,9MDP000014376546,0MDP000031965946,5MDP000016624546,7MDP000019493547,6MDP000016409548,4MDP000013741549,1MDP000079078850,9MDP0000141206 MDP000017839551,1MDP000021184851,2MDP000087104252,8MDP000012624555,4MDP000051803255,5MDP000025463256,1MDP000071631556,3MDP0000580327 MDP000081944057,9MDP000011986461,3MDP000013040061,4MDP000029152263,4MDP000020085163,9MDP000063869164,4MDP000030253166,0MDP000085227166,1MDP000072205268,2MDP000090282268,5MDP000016605969,0MDP0000271809 MDP000089219869,2MDP0000178326 MDP000030630271,1MDP000014736873,9MDP0000397540 MDP000016112374,3MDP0000218344 MDP000025289074,5MDP000025196675,3MDP000021869975,4MDP0000552328 MDP000024677575,5MDP000012380875,6MDP000048658975,9MDP000086503276,8MDP0000714374 MDP000073133077,2MDP000025227477,8MDP000052972678,1MDP000013872180,1MDP000042062880,2MDP000032303680,5MDP0000121788 MDP0000259640 MDP000078541380,6MDP000027698280,7MDP0000138004 MDP0000188551 MDP000040012980,8MDP0000294251 MDP000013746181,4MDP000019667782,1MDP000013410582,3MDP0000652760 MDP000012797682,4MDP0000657701 MDP000084776682,5MDP0000155054 MDP000014584182,8MDP000018226583,5MDP000013076985,6MDP000041820185,7MDP000025899985,8MDP000086993985,9

chr_9

MDP00003792882,2MDP00008399213,1MDP0000242242 MDP00001447903,9MDP0000286230 MDP00004471494,5MDP00002083345,3MDP00002041256,5MDP0000200486 MDP0000720967 MDP00004665466,6MDP0000224878 MDP00002426566,7MDP00002350287,0MDP00003195007,2MDP00001719907,3MDP00003440268,2MDP0000270062 MDP000024813010,6MDP0000686217 MDP000014941110,8MDP000025835910,9MDP0000245702 MDP000013589811,1MDP000074660511,4MDP000026463412,1MDP0000222941 MDP000021899212,3MDP000030004312,9MDP000084994414,7MDP000015900015,8MDP000057692215,9MDP000021559017,1MDP000029068017,5MDP000018359317,9MDP000028360618,6MDP000028108018,7MDP000076237318,9MDP000015967019,2MDP000013093120,5MDP0000587659 MDP000065001720,9MDP000074151421,0MDP000017230321,2MDP000013756122,0MDP000013187426,3MDP000020563726,6MDP000025447029,2MDP0000412939 MDP000075265629,8MDP0000132452 MDP0000147628 MDP0000699607MDP000067889131,3

MDP0000491020 MDP000024956431,5MDP000022357032,2MDP000012552032,3MDP000015477732,4MDP000056804533,4MDP000048058133,6MDP000019258634,8MDP000014470335,3MDP000028098037,0MDP000018163037,1MDP000020511338,4MDP0000554450 MDP000050922940,3MDP0000302503 MDP000017182242,1MDP000028964242,5MDP0000679946 MDP000023576542,6MDP000015686643,4MDP000030423643,8MDP0000284467 MDP0000668966 MDP000025087643,9MDP000032001744,3MDP000016864645,0MDP000032673445,4MDP000069703046,0MDP0000246388 MDP000085567146,7MDP0000187369 MDP000028691546,9MDP0000139773 MDP000093486647,2MDP0000163720 MDP000026912647,3MDP000087877347,4MDP000036390448,2MDP000022427548,6MDP000013170248,7MDP0000872262 MDP000041555848,8MDP000062621548,9MDP000045750949,1MDP000028196549,2MDP0000176747 MDP000017674949,4MDP0000176753 MDP000001008649,5MDP0000220092 MDP000013770549,7MDP000081380549,9MDP000013068651,5MDP000070212051,9MDP000022515952,2MDP0000310875 MDP000021914652,4MDP000021914852,5MDP000019078855,7MDP000056600556,5MDP000079136456,6MDP000013326257,1MDP000084041758,8MDP000014582759,0MDP000026873259,2MDP000027460659,4MDP000030942559,6MDP000011959059,7MDP000026489460,3MDP000032416660,6MDP000031660961,3MDP000013391862,1MDP0000732246 MDP0000711750 MDP000032087262,6MDP000013824963,4MDP0000689946 MDP000043068263,9MDP0000319451 MDP000031149264,1MDP000017965064,2MDP000030935164,4MDP000081452464,7MDP0000287570 MDP000021052164,8MDP000028735865,3MDP000027284365,4MDP000082112466,1MDP000012088066,7MDP000012088166,8MDP000030586167,4MDP000074078769,3MDP000049674569,4MDP0000199152 MDP000029890369,5MDP0000245233 MDP000052552769,9MDP000021015570,0MDP000017939672,8MDP000018154472,9MDP000021763374,0MDP0000289069 MDP000093565274,3MDP000019588574,8MDP0000274205 MDP000025874474,9MDP000029438475,0MDP000080745675,9MDP0000309469 MDP000020551576,3MDP0000265913 MDP000029940276,7MDP000028558976,8MDP000013456676,9

chr_10

MDP00003923380,0MDP0000928605 MDP0000169709 MDP00007336210,1MDP0000201513 MDP0000305929 MDP0000172804MDP00003141910,7MDP00005235791,0MDP00008433031,4MDP0000189193 MDP0000130808 MDP0000268101MDP00003202151,5

MDP00006222411,6MDP00002341662,7MDP00005654022,8MDP00008767383,3MDP0000528870 MDP00003076854,2MDP0000182395 MDP00004857764,5MDP00002958125,6MDP0000277666 MDP00003003215,9MDP00002010116,0MDP0000203847 MDP0000562585 MDP0000565880MDP00002448736,1

MDP0000162617 MDP0000264453 MDP00002448776,3MDP0000611903 MDP00006187746,4MDP00003013477,1MDP00001692878,0MDP00001987369,0MDP0000282880 MDP00001782149,1MDP0000215099 MDP00001306539,6MDP000046470411,3MDP000022934811,5MDP0000940078 MDP0000297791 MDP0000305387MDP0000893848 MDP000026287811,7

MDP0000144544 MDP0000215725 MDP0000155454MDP000013850011,8

MDP0000265416 MDP0000507969 MDP000015887612,2MDP000038272012,6MDP000027709312,8MDP000026706412,9MDP000093599613,0MDP000019574113,3MDP0000172662 MDP000030914213,4MDP0000382514 MDP0000859587 MDP000039663013,7MDP0000686301 MDP0000471565 MDP0000739392MDP0000222559 MDP0000156246 MDP0000263453MDP0000313145

13,8

MDP000027605713,9MDP0000173539 MDP0000902216 MDP0000376869MDP0000396403 MDP0000379060 MDP000022976314,0

MDP000016782914,4MDP000023303715,1MDP000016349015,3MDP000016601615,7MDP0000148746 MDP0000171771 MDP000039411616,1MDP000028995516,5MDP000026413116,6MDP000016301716,7MDP0000323136 MDP000009203316,8MDP000050418317,8MDP000045671618,3MDP000018585618,4MDP000026756118,5MDP0000551467 MDP000030462519,3MDP000020997421,1MDP000092183422,2MDP000065309522,6MDP000090721822,7MDP000030746723,6MDP0000885802 MDP000085932524,7MDP000064479725,2MDP000014086425,5MDP000018160625,8MDP000017301126,2MDP0000196330 MDP000024647026,7MDP000041627926,8MDP0000228273 MDP0000701129 MDP000021349426,9MDP000041278127,3MDP000025588427,7MDP000049864528,4MDP000027444228,8MDP000037597128,9MDP0000265616 MDP000019198129,1MDP000069143129,5MDP0000125980 MDP000080798429,6MDP000059303131,0MDP000080474131,4MDP000031176531,5MDP0000285555 MDP000021355535,7MDP000028939736,6MDP0000163058 MDP000023043437,1MDP000090654237,2MDP0000629527 MDP0000311969 MDP000054263338,6MDP0000153227 MDP0000186640 MDP0000286362MDP0000292291 MDP0000173000 MDP000063181338,7

MDP0000139929 MDP0000243770 MDP0000483239MDP000014624839,5

MDP000029318443,0MDP000023902643,5MDP000024011345,9MDP000068416947,3MDP000018368248,6MDP000052885751,2MDP0000853065 MDP000024643653,0MDP0000157209 MDP000023301053,3MDP000088212754,0MDP0000177696 MDP0000202631 MDP000030857654,1MDP000013812254,2MDP000020619954,6MDP000020686854,7MDP0000233948 MDP000023384355,0MDP0000391188 MDP000049014957,6MDP000031768658,1MDP0000165921 MDP000026480358,5MDP000040244459,4MDP000029650859,5MDP000031711960,1MDP000083678160,4MDP000069376560,7MDP0000130635 MDP000027697660,9MDP000027484761,0MDP0000380592 MDP000014004161,1MDP000025951161,9MDP000013457262,5MDP0000213111 MDP000028941362,6MDP000086858764,4MDP000044231064,8MDP000078830464,9MDP0000180890 MDP0000766342 MDP000016278365,4MDP000024437765,5MDP000013369866,1MDP000082131467,7MDP000028480867,9MDP000065566668,2MDP000057010269,9MDP0000169346 MDP000016963570,0MDP000023062771,1MDP000026281572,6MDP000020589072,8MDP000030446272,9MDP0000614281 MDP000088045373,2MDP000022568074,4MDP000023124576,4MDP0000138860 MDP000021435276,9MDP000012597577,1MDP000020438177,9MDP0000288465 MDP000028846878,3MDP0000126944 MDP000012694678,4MDP0000603805 MDP0000126947 MDP0000126948MDP000032003978,5

MDP0000929168 MDP000023196278,6MDP000013662379,0MDP0000202282 MDP000017421679,4MDP000020229279,5MDP0000234798 MDP000094932779,6MDP000022680979,8

chr_11

MDP00001840690,4MDP00001775471,3MDP00007700891,5MDP00002543721,9MDP00002284072,2MDP00001790363,9MDP0000179040 MDP00002303084,0MDP0000126707 MDP0000151497 MDP00008336414,2MDP0000177486 MDP00001441054,9MDP00008963076,0MDP00002874236,7MDP00002062127,0MDP0000281064 MDP00002271157,8MDP0000523644 MDP000071302410,1MDP000023233810,2MDP000029714210,6MDP000030952113,2MDP0000871361 MDP000070362617,2MDP000087480017,4MDP0000168416 MDP0000220329 MDP000014790218,0MDP000079326819,1MDP0000814798 MDP0000313984 MDP0000169669MDP000021158119,2

MDP000022843719,4MDP000013810221,3MDP000026221022,2MDP000061551425,1MDP000025522325,3MDP000078466526,7MDP0000279249 MDP000084191828,0MDP000078770128,1MDP000029605028,2MDP0000285032 MDP0000250395 MDP0000688348MDP000011629628,3

MDP0000057153 MDP000068837628,4MDP0000257406 MDP0000682530 MDP000017314328,6MDP000059594128,9MDP000031150029,1MDP000083617029,3MDP000046841130,6MDP000013795431,4MDP000040686032,9MDP000004142133,9MDP000028050634,5MDP0000665087 MDP000071515434,6MDP0000123864 MDP000037095634,8MDP0000370957 MDP0000238208 MDP000093184234,9MDP000019243435,0MDP0000460051 MDP000056102635,4MDP000018004336,0MDP000069680437,6MDP000080367437,7MDP0000179216 MDP000018419537,8MDP000015737038,2MDP0000388769 MDP000013907538,5MDP000016724639,5MDP0000756357 MDP000018865539,6MDP0000246825 MDP0000560923 MDP000018525639,9MDP000060033642,3MDP0000586302 MDP000026451442,6MDP0000908969 MDP000027491142,8MDP000016364544,2MDP000026836444,5MDP0000201945 MDP000059842844,6MDP000015681545,4MDP000032262745,9MDP000032135347,8MDP000074323948,3MDP000013876448,5MDP000011909248,6MDP0000255768 MDP000020596248,8MDP000014862648,9MDP000024423150,1MDP000011922350,2MDP000017336050,5MDP000022360951,6MDP0000250924 MDP0000139446 MDP000025092751,7MDP000044871551,9MDP0000494976 MDP0000832632 MDP000025236952,2MDP0000278118 MDP000027811952,3MDP000034100852,4MDP0000390437 MDP0000651396 MDP000030466654,1MDP0000242852 MDP000016108455,9MDP0000492744 MDP000036080856,4MDP000050876156,8MDP0000319736 MDP000059830358,0MDP000067245458,2MDP0000750456 MDP000028741658,9MDP000017877859,3MDP0000951202 MDP000088031260,4MDP000024401860,5MDP0000296025 MDP0000195385 MDP0000298852MDP000014610860,7

MDP0000718993 MDP000063400661,2MDP0000912745 MDP000025308561,3MDP0000219509 MDP0000432773 MDP000052452261,6MDP0000706439 MDP000070915361,7MDP0000902285 MDP000074704561,8MDP000015485561,9MDP000014194762,4MDP0000765613 MDP000069459762,5MDP0000285074 MDP0000661371 MDP0000285078MDP0000306486 MDP000030648762,6

MDP000021025162,8MDP000082412863,0MDP000046013963,2MDP0000754989 MDP000075499263,3MDP000012009863,4MDP000015634363,9MDP000016214364,0MDP000017009564,7MDP0000286498 MDP0000186817 MDP000018681864,9MDP000020215665,0MDP000029026365,1MDP0000307605 MDP0000834768 MDP000059944965,2MDP000063463065,4MDP000018105365,6MDP0000802803 MDP000029450466,0MDP000027826066,1MDP000086913766,3MDP000020316866,8MDP000030989966,9MDP0000296741 MDP000020034067,3MDP0000125303 MDP0000168536 MDP0000520035MDP000017209268,9

MDP0000146677 MDP0000081005 MDP0000120271MDP0000312394 MDP000026388469,0

MDP000002541369,3MDP000067213169,8MDP000093130270,8MDP000017640972,0MDP000078537972,1MDP000025502572,4MDP000027036573,0MDP0000945260 MDP0000663301 MDP0000234335MDP000075617373,1

MDP000023117273,5MDP000087168973,7MDP000032232975,7MDP000018404475,8MDP000013272375,9MDP0000260362 MDP000025175976,1MDP000087108076,3

chr_12

MDP00002483310,3MDP00003113040,5MDP00001709070,6MDP00001887500,7MDP0000130290 MDP00005614770,8MDP0000297336 MDP00002081052,2MDP00001518252,3MDP00002717703,1MDP0000171235 MDP0000242396 MDP0000284687MDP0000306441 MDP00003068373,2

MDP0000245769 MDP0000293915 MDP0000251013MDP0000213733 MDP0000299199 MDP0000192132MDP0000887754 MDP0000815791 MDP0000546004

3,3

MDP00003112553,8MDP0000549961 MDP0000503044 MDP00004975813,9MDP00001665704,4MDP00002777755,2MDP00002594955,9MDP00003109816,1MDP0000239442 MDP0000547788 MDP00002416626,2MDP0000743350 MDP00001199566,4MDP0000145555 MDP00003018846,8MDP00001289247,0MDP00001658457,1MDP00002714207,2MDP00001133367,3MDP00008918998,5MDP0000322436 MDP00006862898,8MDP00001492228,9MDP0000269921 MDP0000197683 MDP00003269069,3MDP00002199079,8MDP00001932169,9MDP000065562310,0MDP000024047410,3MDP000012578210,4MDP000084951410,5MDP000048144810,9MDP000056011211,0MDP000018676511,5MDP000029432411,7MDP000021097912,0MDP000027385112,4MDP0000281784 MDP000045426912,5MDP000019557913,3MDP000031231613,8MDP0000213640 MDP0000228207 MDP000085985715,0MDP000083415615,1MDP000023995815,2MDP000020914815,6MDP0000324249 MDP000082740016,9MDP000074092717,0MDP000070551017,1MDP0000250058 MDP000081536817,3MDP000072981717,7MDP0000319156 MDP000049189818,0MDP000063169818,1MDP000075756519,1MDP000015466819,6MDP000021262120,1MDP000064646720,4MDP000030901420,7MDP0000155347 MDP000087827921,0MDP000093623221,1MDP0000370413 MDP000079208821,2MDP000012651722,0MDP000020196624,5MDP000039012124,9MDP000022684225,2MDP000026300825,4MDP000032398725,9MDP0000279891 MDP0000279892 MDP0000905103MDP000021904126,2

MDP000030373527,1MDP000031093627,7MDP000029641628,4MDP000022640528,8MDP000019237228,9MDP0000305934 MDP0000212539 MDP000018320429,2MDP0000133148 MDP000018683429,3MDP000014639029,4MDP000020209429,5MDP000052371529,7MDP0000823143 MDP000031487231,3MDP000065607831,6MDP000025838731,7MDP000085795832,4MDP0000165867 MDP000018468732,5MDP000014217433,2MDP000027151333,4MDP000035043133,6MDP000018934735,0MDP000028845235,1MDP000027675035,3MDP000012017635,9MDP000019315136,7MDP0000236701 MDP000013292636,9MDP000012897938,2MDP000022138338,3MDP000058140638,4MDP0000293214 MDP000030445538,5MDP0000686191 MDP0000389664 MDP000078585238,6MDP000059264938,7MDP0000285581 MDP000024649339,5MDP000065869641,0MDP000021116541,1MDP000077814041,3MDP000023994741,4MDP000014386044,6MDP000031877246,2MDP000059462146,9MDP000081312947,2MDP000020492947,3MDP000028909847,4MDP000025747447,8MDP000013728349,5MDP000031342550,3MDP000031085454,6MDP000009692355,1MDP000019639455,2MDP000030314255,3MDP000021386455,5MDP000019560856,2MDP000021318760,1MDP000013342362,0MDP000019763862,2MDP000020593863,0MDP000032241864,1MDP000092018964,8MDP000081949965,2MDP000027675865,3MDP000082574965,4MDP0000133854 MDP000082992565,5MDP0000127134 MDP000016720765,8MDP000024340468,9MDP0000801765 MDP000026273669,0MDP0000140747 MDP000014512369,3MDP0000194557 MDP000073104770,0MDP0000273194 MDP000016910870,1MDP000022395970,2MDP000082417871,2MDP000042819971,7MDP000075551171,8MDP000015493271,9MDP000021918472,1MDP000088709372,4MDP000018525372,7MDP0000431572 MDP000044189173,4MDP000008454673,6MDP0000145734 MDP0000285495 MDP000012555474,0MDP000022975574,4MDP000080032278,4MDP000074098178,5MDP000022274478,9MDP000020406679,2MDP000061924479,7MDP0000841540 MDP000021969680,0MDP000077428880,1MDP000014684880,9MDP0000121984 MDP000031692981,4MDP0000138669 MDP000055783681,6MDP000018133981,7MDP000013347682,0MDP000094504282,2

chr_13

MDP00001806830,2MDP00001283260,6MDP00005352740,9MDP0000939989 MDP00002894282,3MDP0000195376 MDP00004513653,0MDP00001216033,3MDP00001524005,7MDP00002524355,8MDP0000506233 MDP00002339215,9MDP00005584936,4MDP00001642977,0MDP00001764477,4MDP0000284245 MDP00005452139,1MDP0000163334 MDP0000183754 MDP00002215909,8MDP0000663451 MDP0000310711 MDP0000299960MDP000053449310,2

MDP0000182809 MDP0000178561 MDP0000162169MDP0000179051 MDP0000467510 MDP000061656510,3

MDP000029679112,7MDP000028753013,0MDP000028939213,1MDP000017622414,3MDP000062697815,0MDP000032023915,1MDP0000482268 MDP000030244016,3MDP000041242716,4MDP0000214409 MDP000022318416,5MDP000012769517,0MDP000076512317,1MDP000090999117,3MDP000088203317,4MDP000032032218,1MDP000018037618,3MDP0000218209 MDP000051314018,6MDP000077306821,9MDP000072209224,4MDP000075933624,7MDP000017742226,0MDP000016410631,4MDP0000129053 MDP000092272331,6MDP0000226447 MDP000031637931,8MDP000078381832,7MDP000079443933,1MDP000086855633,5MDP000032226438,2MDP0000126350 MDP000015544641,7MDP0000146144 MDP000055522041,9MDP0000146334 MDP000021534642,3MDP000014022943,4MDP000018828944,7MDP000047246244,8MDP000018331344,9MDP000056178845,0MDP000026690845,4MDP000031684345,6MDP000019027345,7MDP000023970145,9MDP000019023746,9MDP0000258032 MDP000066299947,4MDP000031384247,6MDP0000147080 MDP000080708748,0MDP000025380248,7MDP000025395248,8MDP000041072849,6MDP000026380150,0MDP000028962951,3MDP000059776751,7MDP0000394944 MDP000020138952,4MDP000032985153,4MDP000016115753,7MDP000028393353,8MDP0000846032 MDP000047943654,0MDP000023911454,1MDP000029300154,2MDP000030794355,3MDP000028046356,6MDP0000165481 MDP0000221713 MDP000015939556,9MDP000015848657,0MDP0000129051 MDP000027932657,1MDP000014249057,3MDP0000158799 MDP000068421657,4MDP0000324559 MDP000021217857,8MDP000029984658,2MDP0000910487 MDP0000218785 MDP0000218786MDP000017521559,0

MDP0000152070 MDP000026398159,1MDP0000153663 MDP0000291218 MDP0000151618MDP000019302559,9

MDP000012126560,0MDP000071527060,9MDP000031924861,0MDP000014226661,2MDP000028696061,3MDP000032639062,2MDP000028983662,3MDP000024286562,5MDP000090513562,6MDP000003965362,7MDP0000300361 MDP0000315837 MDP0000282599MDP0000157628 MDP000019737562,8

MDP000027320164,3MDP0000130785 MDP000077935864,4MDP000016002664,9MDP000031382065,0MDP000093371165,1MDP000029695865,8MDP000093104865,9MDP000013803566,1MDP000082361266,5MDP0000384932 MDP0000319849 MDP000023127466,6MDP0000656113 MDP000021259367,7MDP000086837268,4

chr_14

MDP00009168790,1MDP00001226240,6MDP00001475271,0MDP00002890431,5MDP00002282821,6MDP00002317181,7MDP00002252312,1MDP0000232577 MDP0000203740 MDP00001642772,9MDP0000308887 MDP00004549383,0MDP0000231650 MDP0000187703 MDP00001753093,1MDP0000146841 MDP00001902773,3MDP00001271013,5MDP00002305303,6MDP0000198037 MDP00005731784,2MDP0000275058 MDP0000296241 MDP00003029704,4MDP00003155334,5MDP00002214665,3MDP00002316685,4MDP00007563415,5MDP00001527745,6MDP0000617871 MDP00004848475,7MDP0000908951 MDP00002048385,8MDP00002494056,0MDP00002963036,2MDP00002904856,4MDP00006250096,9MDP0000123213 MDP00002781247,4MDP0000267601 MDP00001305837,9MDP0000219296 MDP00003099298,4MDP0000307237 MDP0000584567 MDP0000058337MDP00007158988,5

MDP00002426118,6MDP0000192227 MDP0000316545 MDP0000271304MDP00002713058,7

MDP00002785888,8MDP00008695899,1MDP00002286739,3MDP00002320089,4MDP00006036309,9MDP000068004210,2MDP0000177665 MDP0000200748 MDP000038189710,3MDP000014944710,5MDP000020364710,6MDP0000272940 MDP000051481210,8MDP000094576710,9MDP000028221313,1MDP000020519714,4MDP0000318601 MDP000014106214,8MDP0000280142 MDP0000429728 MDP000017826315,0MDP0000193822 MDP000026594215,3MDP000017453715,5MDP000033404717,3MDP000053469018,4MDP0000845683 MDP000084568518,7MDP000019145318,9MDP0000667743 MDP000027216419,6MDP000030985319,7MDP000026009219,8MDP0000762267 MDP000026795119,9MDP000027140520,2MDP000013121820,3MDP000063217320,4MDP0000526584 MDP0000121522 MDP000053478420,7MDP000019043021,1MDP000019671121,3MDP000030281521,4MDP000045879922,0MDP000065168922,6MDP000037625623,7MDP000053130124,0MDP000016438625,3MDP000021391625,9MDP0000389195 MDP000047750326,1MDP000016868126,2MDP000092131926,3MDP000029927728,4MDP000019546028,8MDP000023040229,6MDP0000290880 MDP000012431629,9MDP000027126830,0MDP0000270132 MDP000024784930,2MDP000025094730,8MDP000015630930,9MDP000025662131,2MDP000076624132,0MDP0000212975 MDP000061290932,8MDP000017545033,6MDP0000153231 MDP0000869545 MDP000075304133,7MDP000039675034,1MDP000032036034,2MDP000024085534,9MDP000043597135,0MDP000049427335,6MDP0000318427 MDP0000828007 MDP000031810135,9MDP000022958836,3MDP000020458236,4MDP000065258437,1MDP000032233038,0MDP000012401938,3MDP000024170338,5MDP000014817839,0MDP000087323539,1MDP000015193439,3MDP000036183839,5MDP000022067539,6MDP0000182782 MDP0000138064 MDP000025272339,7MDP0000259556 MDP000020659339,8MDP0000888095 MDP0000701077 MDP000025669639,9MDP0000424978 MDP000025906240,1MDP0000067999 MDP000021595841,3MDP000015707041,6MDP0000612482 MDP000061865041,7MDP000019898041,9MDP0000177299 MDP000021886842,1MDP0000576178 MDP000018506742,8MDP0000503341 MDP000023295242,9MDP000022670143,0MDP000037509243,4MDP000029017043,7MDP000051725743,9MDP0000799290 MDP000051726244,0MDP000020089646,0MDP000054601846,5MDP000078290847,0MDP000080494647,3MDP0000440622 MDP000056102247,4MDP000077895548,4MDP0000848702 MDP000039302248,6MDP000025866148,8MDP000015404649,8MDP0000665685 MDP000078728151,2MDP0000421802 MDP000041709551,6MDP000017085352,2MDP000016947352,9MDP000027349553,2MDP000027671153,3MDP0000124752 MDP000026005253,4MDP000025323153,5MDP000027563553,8MDP000072742656,0MDP000030966156,1MDP000067208857,2MDP000017359360,7MDP000018861061,3MDP000055723462,1MDP000016245662,3MDP000080494962,4MDP000014229263,1MDP000014723263,5MDP0000152668 MDP000024531265,2MDP000013252765,8MDP000039285966,0MDP0000654314 MDP000026765167,0MDP000092109468,0MDP0000159013 MDP000019885868,1MDP0000204900 MDP000018245568,6MDP000017996268,7MDP000029835269,2MDP000030356769,3MDP000017858671,4MDP000066653971,5MDP000087286871,6MDP000094091071,7MDP000022598071,9MDP000026115472,8MDP000068910573,0MDP000048528076,0MDP000012869576,6MDP000037538476,9MDP000012353079,5MDP000037140182,6MDP000012125884,4MDP000018037884,6MDP000014492285,3MDP0000453797 MDP000068381485,5MDP000030780986,3MDP000025853086,7MDP000024631986,8MDP000091089590,0MDP000017316097,4MDP000093346197,5MDP000003189598,5MDP000022478998,6MDP000027799998,9MDP000023211699,1MDP000012516799,6MDP0000736385100,3MDP0000309179 MDP0000762567100,7MDP0000809218101,8MDP0000181746102,0MDP0000258316 MDP0000289583102,7MDP0000196806 MDP0000297196103,0MDP0000470297103,7MDP0000191908104,0MDP0000682893 MDP0000744887 MDP0000769041104,1MDP0000846004 MDP0000295375104,2MDP0000234911105,2MDP0000194413105,4MDP0000090281106,3MDP0000644807106,6MDP0000759612106,8MDP0000794858107,8MDP0000578301108,3MDP0000129112108,7MDP0000134211109,0MDP0000602946110,3MDP0000163213111,7MDP0000052862 MDP0000688415 MDP0000269890MDP0000361449 MDP0000219282112,0

MDP0000375160 MDP0000192342112,1MDP0000306684 MDP0000137051 MDP0000311403112,9MDP0000122739 MDP0000122740 MDP0000151428MDP0000283350113,5

MDP0000932292113,8MDP0000410215113,9MDP0000293049115,4MDP0000204234115,5MDP0000718430115,6MDP0000386318 MDP0000266480116,5MDP0000122864117,0MDP0000189394117,1MDP0000142765117,5MDP0000206102117,6MDP0000330776117,7MDP0000225700 MDP0000140388117,8MDP0000181608 MDP0000198495118,5MDP0000483865118,6MDP0000246042119,1MDP0000303501120,0MDP0000052608 MDP0000052605120,6MDP0000137704 MDP0000757476122,1MDP0000272284 MDP0000140294 MDP0000209790MDP0000922614 MDP0000501238122,8

MDP0000302012 MDP0000297862 MDP0000279706128,4MDP0000423881129,3MDP0000249285 MDP0000249275129,5MDP0000220211130,3

chr_15

MDP00002547240,5MDP00002342910,6MDP00008266000,8MDP00006735531,3MDP00002994961,4MDP00002345282,7MDP00001814293,0MDP0000137803 MDP00002483763,2MDP00001734774,4MDP00007259915,0MDP0000185022 MDP00003924855,3MDP00007592995,4MDP00009396335,9MDP00002245926,0MDP00003197266,1MDP0000183562 MDP00001542726,9MDP00002215637,1MDP00002612937,2MDP00001311007,5MDP0000457996 MDP0000695714 MDP0000013331MDP00002800098,0

MDP0000255565 MDP0000236349 MDP00009185668,6MDP0000707539 MDP00005485118,8MDP0000233503 MDP00005601799,0MDP00002582129,1MDP0000364750 MDP00002629909,5MDP0000681724 MDP00001476679,7MDP000024182110,1MDP000024142410,4MDP000016188110,7MDP000016281710,8MDP000028260011,4MDP000032887411,9MDP000023095012,1MDP000014380412,2MDP000054765512,8MDP000023317712,9MDP000019177413,0MDP000016405413,1MDP0000790939 MDP000044449413,3MDP000027825413,5MDP000024767214,0MDP000012317214,6MDP000023531815,0MDP000075336615,3MDP000027714915,7MDP000026660315,8MDP0000222620 MDP0000162904 MDP000066853716,1MDP0000621927 MDP0000645828 MDP000031926316,3MDP0000129547 MDP000021540516,6MDP000030892216,8MDP0000535983 MDP000019111017,6MDP000015006818,1MDP000031080018,4MDP0000220008 MDP000061640218,5MDP000012388818,6MDP000013012319,4MDP000073574720,1MDP000018645220,5MDP0000176288 MDP000013703520,6MDP0000249104 MDP000024910520,7MDP000025651420,8MDP0000195096 MDP000086531321,5MDP000028511021,6MDP000028310621,8MDP000024600623,6MDP000023361424,2MDP000013175924,8MDP000023703927,8MDP000029444428,2MDP000023676828,6MDP000013779228,7MDP0000252150 MDP0000413387 MDP000077757928,9MDP000015254831,9MDP000025767332,0MDP000046775332,2MDP000017746833,1MDP000079887833,4MDP000022487534,3MDP000020503035,5MDP0000204470 MDP000039893136,6MDP0000246150 MDP0000942265 MDP000019774338,2MDP000015293839,1MDP000023987839,3MDP000014103339,7MDP000019716040,3MDP000020834540,7MDP000032491940,9MDP0000289177 MDP0000287577 MDP000012481041,1MDP000031432141,9MDP000028684642,8MDP000029269543,0MDP000044036743,8MDP000093626944,0MDP000025514644,3MDP000032256744,4MDP000056262744,6MDP000023531345,7MDP000028669347,5MDP000028177347,7MDP000013482448,3MDP000045979449,5MDP000024076650,4MDP000069317451,1MDP000029539251,5MDP0000211803 MDP000087101051,6MDP0000369941 MDP000017985151,7

chr_16

MDP00003620330,1MDP0000580186 MDP00006889000,2MDP00002479120,6MDP0000203334 MDP00004699430,8MDP00008427020,9MDP00001425831,5MDP00002081971,6MDP00008929792,0MDP0000145439 MDP00002754122,8MDP00002839753,5MDP00002817774,4MDP0000280003 MDP00009112785,6MDP0000576836 MDP00005758236,1MDP0000159916 MDP0000942526 MDP00002611586,2MDP00001574297,3MDP0000301545 MDP0000206674 MDP00002066767,9MDP00002903748,1MDP00002400278,5MDP00006709599,1MDP0000232050 MDP00001293359,2MDP0000184228 MDP00003209329,5MDP0000551969 MDP00001284649,6MDP0000286574 MDP0000544455 MDP0000120215MDP000025352310,2

MDP000035152610,5MDP0000164967 MDP000027005110,8MDP000050151811,9MDP0000246204 MDP000016025612,1MDP0000271553 MDP000024319412,3MDP000072601212,6MDP000025357612,7MDP000024066313,7MDP000027758215,0MDP0000366022 MDP000089588315,3MDP000086390916,0MDP0000240648 MDP000027718316,5MDP000094526717,0MDP000032156917,1MDP000021241117,3MDP000032802618,0MDP000019237418,4MDP0000214081 MDP000023817318,7MDP0000186131 MDP0000229036 MDP000022609919,6MDP000040440919,9MDP0000290585 MDP0000378203 MDP000013243120,2MDP000013649820,4MDP000032268820,6MDP0000297049 MDP000081771020,7MDP0000641681 MDP000040475421,7MDP0000143216 MDP000075387021,9MDP000016837524,2MDP0000121713 MDP000023007424,7MDP000088599524,9MDP000025253625,3MDP000025129525,7MDP000083982826,1MDP000021249626,5MDP000025186426,8MDP000058283626,9MDP000026080327,1MDP000023959627,3MDP0000184361 MDP000017580927,7MDP0000300536 MDP000029095828,9MDP000020128129,4MDP000015072130,3MDP0000133911 MDP000015072930,4MDP000078001130,9MDP0000193401 MDP0000128410 MDP0000915151MDP000029986031,1

MDP0000159635 MDP0000311467 MDP000021995031,2MDP000080490031,3MDP000042866031,4MDP0000246674 MDP000020877831,7MDP0000873295 MDP0000806350 MDP000023897632,0MDP0000764876 MDP000036151132,1MDP0000219404 MDP0000215774 MDP000014739132,2MDP0000319957 MDP000015353832,4MDP000011874832,8MDP000019840432,9MDP000017762333,1MDP000072114933,5MDP000025712934,2MDP000022920534,3MDP0000248336 MDP0000173145 MDP000019872734,7MDP000024200934,9MDP000026374435,2MDP000030915935,6MDP000052361935,7MDP000086508435,9MDP000027994336,4MDP000031568837,6MDP000059627539,5MDP000040162939,6MDP0000755167 MDP000031888439,7MDP000025739041,4MDP000017435243,6MDP000091758243,8MDP000026260244,0MDP000087090946,7MDP000037079147,2MDP0000310152 MDP000021317947,8MDP0000235201 MDP0000247298 MDP000024730048,9MDP000088958049,1MDP000027078949,4MDP000087052151,0MDP000017790652,4MDP000023174852,9MDP000025318953,2MDP0000617184 MDP0000137451 MDP000010767653,7MDP000055545755,3MDP000026079055,5MDP000012497155,6MDP000029093456,6MDP000070970556,9MDP000041763257,0MDP0000435467 MDP000012053957,4MDP000026612557,5MDP0000216705 MDP0000524809 MDP000073148057,6MDP0000764803 MDP0000311856 MDP000022045857,7MDP0000951949 MDP0000205224 MDP0000201743MDP0000211736 MDP000043179058,0

MDP000047474658,4MDP000029120060,0MDP0000051653 MDP0000466825 MDP000030501762,0MDP0000187925 MDP000073929563,0MDP0000132870 MDP0000123429 MDP0000520807MDP0000272179 MDP000027771163,2

MDP0000204870 MDP0000204871 MDP000029364963,3MDP000055004963,6MDP000065744164,4MDP000016118164,6MDP0000299357 MDP0000260152 MDP0000279599MDP0000784451 MDP000046888165,0

MDP0000145267 MDP000093194065,3MDP000017292265,4MDP000085080265,5

chr_17SNP array under constructionS Factorial component analysis (FCA) over ~1800 unique diploid genotypes/accessionsNP array under construction

Research and Innovation Centre

SNP chip physical genome coverage

• ontogenic resistance

• QTLs

• resistance gene17 R-avirulence: tre principal actions

1- HR(Vm, Vh4, Vr2)

3- Chlorosis(Vb, Vmis, Vf)

2- Stellate necrosis(Vh2, Vh8, Vg)

•Marker assisted selection (MAS) per la scab resistance•Marker available for 10 of 17 geni di melo resistent (Vf, Vg, Vd, Vb, Vbj, Vr2, Vm, Vh2, Vh4, Vh8).•Possible use in fast breeding strategy to piramidate resistance genes in one new cultivars.

Molecular markers assisted selectionn

x

GD

M. floribunda

Source of Vf gene, resitance to apple scab

traditionsl

assisted

Breeding by design

Genomics-assisted breedingFruit quality Plant habit

ResistanceYield

Elite lines

‘Genomics’ intervention points:

1. Genetic control of traitsLinkage and association

2. Germplasm collection3. Supporting apple breeding with MAS:

Parents and Seedlings selection

Applied Molecular Genetics - Apple

Resistant genotypes:which is the possible future?

Applied genomics to Malus spp.

FEM Research:

18 hectares dedicated to

apple breeding

Pipeline has to be: -“lab friendly” -unambiguous seedling configuration in greenhouse-avoid cross contamination-cost effective-quick an efficient high throughput

Development of a screening pipeline

“Quick‘n' dirty” DNA extraction – KAPA 3G Plant PCR “Reducing contamination protocol”, heating a 15 mm leaf disk in a buffer.

Pipeline:1.DNA amplification (KAPA 3G Plant PCR kit – optimized)2.Capillary electrophoresis of the PCR products on ABI 96-capillary 3730xl 3.Data Analysis with GeneMapper v.4 Sotfware

Development of a screening pipeline

Scree

ned 6

471

individ

uals f

rom

24 cr

osses

in 3

weeks

Development of a screening pipeline

KAPA 3G Plant PCR kit has been optimized both during the “quick’n’dirty” extraction and PCR amplification, reducing the failed analysis to less than 10%.

Breeding and promotion Consorzio Innovazione

Frutta (CIF)

Materials available for the joint project AppleberryMaterials available for the joint project Appleberry (consortium CIF) (consortium CIF)

Centro Ricerca e Innovazione Dr. Riccardo Velasco

- 1.663 genotypes in collection (completely characterized with 17 microsatellites markers)

- 240 analysed for metabolic profiles

- 480 charaterized with 20.000 markers (DNA Ilumina chip array for the correlation genotype-phenotype)

- 320 plants in phase 2 (characterized with 17 markers for registration)

- 50.000 new individuals (phase 1 – 5.000 new each year)

Total crosses tested in the 2012: 38 Total crosses tested in the 2012: 38 Total markers tested: 29.115 on 10.735 plantsTotal markers tested: 29.115 on 10.735 plants

Centro Ricerca e Innovazione Dr. Riccardo Velasco

Third year of production, resistances to apple scab & powdery mildew

Segregating individuals of the same cross

First individuals with pyramidized resistances to three diseases

Plant 2 years old, resistant to powdery mildew and apple

scab

Plant 2 years old, resistant to powdery mildew, apple scab

and fire blight

…a lot still to be done!

Michela TroggioLuca BiancoAlessandro CestaroDiego MichelettiFabrizio CostaPierluigi MagnagoDan SargentMassimo DelledonneAlice TadielloSara LonghiEric Van de WegMarco BinkMario di GuardoSudharshan PadmarasuSue GardinerDavid Chagne’Sook JungDorrie MainIlla EudaldPere ArusCharles Eric Durel…and many others

Thanks for your attention