1. Generic Dozile TabletsGeneric Dozile Tablets (Doxinate Tablets) is usedfor the temporary relief of sleeplessness becauseof its sedative effect. It is also used for the relief ofnausea and vomiting during pregnancy. The Swiss Pharmacy, Geneva Switzerland

2. Generic Dozile TabletsChemical Structure The Swiss Pharmacy, Geneva Switzerland 3. Generic Dozile TabletsIndicationsGeneric Dozile Tablets (DoxylamineSuccinate) is an ethanolamine derivativeantihistamine. Because of its sedativeeffect, it is used for the temporary relief ofsleeplessness. It is also used for the reliefof nausea and vomiting duringpregnancy. Generic Dozile is also used incombination with antitussives anddecongestants for the temporary relief ofcold and cough symptoms. The Swiss Pharmacy, Geneva Switzerland 4. Generic Dozile TabletsIndicationsIt is an antihistamine with hypnotic,anticholinergic, antimuscarinic and localanaesthetic effects. Duration of action is6 to 8 hours. The Swiss Pharmacy, Geneva Switzerland 5. Generic Dozile TabletsActive IngredientThe active pharmaceutical ingredientcontained in Generic Dozile Tablets isDoxylamine Succinate. Doxinate containsDoxylamine Succinate 10 mg andPyridoxine HCl 10 mg. Doxinate Pluscontains Doxylamine Succinate 10 mg,Pyridoxine HCl 10 mg and Folic Acid 2.5mg. Doxinate OD contains DoxylamineSuccinate 20 mg and Pyridoxine HCl 20mg. The Swiss Pharmacy, Geneva Switzerland 6. Generic Dozile TabletsRecommended DosageThe recommended dosage for the treatment ofvarious indications is given below:Relief of Insomnia: 1 tablet 30 minutes beforeretiring, or as directed by the doctor. Maximumstated dose should not be exceeded. Generic Dozileis recommended for occasional use only i.e. forperiods of no longer than a week at a time. Ifsleeplessness persists, consult your doctor. GenericDozile is not recommended for children under 12years of age. The Swiss Pharmacy, Geneva Switzerland 7. Generic Dozile TabletsRecommended DosageFor Relief Of Nausea And Vomiting DuringPregnancy: 2 tablets of Generic Dozile(Doxinate / Doxinate Plus Tablets) at bed time, onein the morning and one in the afternoon if requiredor as prescribed by the doctor. Maximum upto 10Tablets of Doxinate / Doxinate Plus Tablets can besafely be given in divided doses. The Swiss Pharmacy, Geneva Switzerland 8. Generic Dozile TabletsContraindicationsGeneric Dozile (Doxinate / Doxinate PlusTablets) is contraindicated in patients withthe following conditions:Hypersensitivity to Doxylamine succinate, otherethanolamine derivative antihistamines or anyinactive component of this medication. The Swiss Pharmacy, Geneva Switzerland 9. Generic Dozile TabletsSide Effects of Generic Dozile TabletsThe most common side effects of GenericDozile Tablets (Doxylamine Succinate)are drowsiness, vertigo, nervousness,epigastric pain, headache, palpitation,diarrhea, disorientation, irritability,convulsions, urinary retention or insomnia,nausea with or without vomiting, andabdominal pain. The Swiss Pharmacy, Geneva Switzerland 10. Generic Dozile TabletsWarnings And PrecautionsCaution should be used if taken with alcohol.Due to the anticholinergic properties of antihistamines,caution should be used when Generic Dozile is takenconcurrently with other medicationsCaution should be taken by those with narrow angle oropen-angle glaucoma, urinary retention, prostateenlargement, pyloroduodenal obstruction, epilepsy orsevere cardiovascular disorders.Doxylamine may suppress positive skin test results.Doxylamine causes drowsiness. Patients should not driveor operate machinery if affected. The Swiss Pharmacy, Geneva Switzerland 11. Generic Dozile TabletsWarnings And PrecautionsUse of Dozile should be avoided during lactation.First generation antihistamines may inhibit lactationbecause of their anticholinergic actions.Generic Dozile is not recommended for childrenunder 12 years of age. The safety and efficacy ofDoxylamine succinate as a night time sleep aid inchildren younger than 12 years of age have not beenestablished.Generic Dozile Tablets (Doxinate / Doxinate Plus)should be administered during pregnancy only ifstrictly required. The Swiss Pharmacy, Geneva Switzerland 12. Generic Dozile TabletsOverdose SymptomsGeneric Dozile (Doxinate Tablets)overdose produces signs and symptomsof anticholinergic toxicity. Acute overdoseof Doxylamine Succinate may causevarious reactions including dry mouth,fixed and dilated pupils, flushing,gastrointestinal symptoms, insomnia,nervousness, euphoria, irritability, tremors,nightmares and hallucinations The Swiss Pharmacy, Geneva Switzerland 13. Generic Dozile TabletsOverdose SymptomsOther overdose signs and symptomsmay include CNS depression orstimulation, impaired consciousness,seizures, tachycardia, mydriasis and apsychosis similar to that in catatonicstupor. Rhabdomyolysis with impairmentof renal function and acute renal failurehas been observed.Fatalities have been reported fromDoxylamine Succinate overdose. The Swiss Pharmacy, Geneva Switzerland 14. Generic Dozile TabletsOverdose TreatmentPatients should be monitored for any abnormalitiesof vital signs. Adequacy of ventilation and bloodpressure should be assessed and full supportivecare, including oxygen and assisted ventilation, beprovided if required. The patient should be observedfor evidence of rhabdomyolysis.Adequate fluid replacement must be provided andgood urine output maintained.Gastric lavage should be considered if it can beperformed soon after ingestion, generally within 60minutes. Most patients recover with symptomaticand supportive care. The Swiss Pharmacy, Geneva Switzerland 15. Generic Dozile TabletsDoxinate / Doxinate Plus Tablets fromSvizera Healthcare, IndiaFor more information click here The Swiss Pharmacy, Geneva Switzerland