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Genetic Evaluation and Index Changes

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Page 1: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

Genetic Evaluation andIndex Changes

Page 2: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

HA-USA Fertility Index

Fertility Index = .64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18 x PTA Heifer Conception Rate (HCR)

Page 3: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

Cow Conception Rate

• Lactating cow’s ability to conceive.• Percentage of inseminated cows that become

pregnant at each service. • PTA CCR of 1 implies that daughters of this bull

are 1% more likely to become pregnant as lactating cows than daughters of a bull with PTA CCR of 0.

• Higher PTA values are better.

Page 4: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

Heifer Conception Rate

• Maiden heifer’s ability to conceive.• Percentage of inseminated heifers that

become pregnant at each service. • PTA HCR of 1 implies that daughters of this

bull are 1% more likely to become pregnant as growing heifers than daughters of a bull with PTA HCR of 0.

• Higher PTA values are better.

Page 5: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

Daughter Pregnancy Rate

• Percentage of non-pregnant cows that become pregnant during each 21-day period.

• Calculated from days open using a non-linear formula.

• Combination of how quickly the cow resumes cycling after calving, how strongly she expresses estrous and her conception rate.

• Higher PTA values are better.

Page 6: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

Multi-Trait Fertility Evaluations

DPR CCR HCRDPR 1.00CCR 0.86 1.00HCR 0.36 0.45 1.00

Fertility as a heifer is a different trait than fertility as a cow.

These 3 traits are evaluated simultaneously in 1 evaluation.

Genetic correlations are used to allow DPR records to contributeto CCR evaluations and improve their reliability and vice versa.

Fertility Trait Genetic Correlations

Page 7: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

7HO8081 Planet

FitnessSomatic Cell Score 3.04 99% RelProductive Life +5.6 99% RelDaughter Pregnancy Rate -1.1 99% RelHeifer Conception Rate +1.6 99% Rel 28,240 DtrsCow Conception Rate +1.3 99% Rel 29,830 Dtrs

33,124 Dtrs

Page 8: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

7HO10849 Shamrock

Fitness

33,124 Dtrs

Somatic Cell Score 2.86 99% RelProductive Life +6.3 94% RelDaughter Pregnancy Rate +2.3 97% RelHeifer Conception Rate +4.2 96% Rel 6,375 DtrsCow Conception Rate +5.2 96% Rel 3,017 Dtrs

4,113 Dtrs

Page 9: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

7HO11402 Tavir

FitnessSomatic Cell Score 3.02 86% RelProductive Life +3.2 82% RelDaughter Pregnancy Rate +0.1 76% RelHeifer Conception Rate +1.6 67% Rel 75 DtrsCow Conception Rate +1.8 74% Rel 35 Dtrs

72 Dtrs

Page 10: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

HA-USA Fertility Index

Fertility Index = .64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18 x PTA Heifer Conception Rate (HCR)

Correlation between DPR and Fertility Index = 98%

Page 11: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

HA-USA Feed Efficiency Index

Feed Efficiency Index =Dollar Value of Milk Produced- Feed Costs for Extra Milk- Extra Maintenance Costs

3% weighting in full TPI formula

Page 12: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

HA-USA Feed Efficiency Index

Feed Efficiency Index =(.0028*Milk)+(1.8*Fat)+(2.95*Protein)

-(.0276*Milk)-( .64*Fat)-( .77*Protein) -(7.44*Body Size Composite)

-0.5% weight on size in full TPI formula

Page 13: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

Feed Efficiency, FeedPRO and TPI

Index Prot DPR SCS PL UDC Body Sz

Stature

Feed Efficiency +.84 -.04 -.06 +.29 -.19 -.17 -.17FeedPRO +.62 +.44 -.35 +.72 +.16 -.32 -.28TPI +.60 +.43 -.42 +.68 +.25 -.02 +.01

Correlation between Indexes and various traits

Page 14: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

Ideal Commercial Cow Index

ICC$ = Wt1 x Prod Efficiency $ + Wt2 x Health $ + Wt3 x Fertility and Fitness $ + Wt4 x Milking Ability $ + Wt5 x Calving Ability $

Page 15: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

Feed PRO Selection Results(as compared to industry average bulls)

Index Milk Fat Prot DPR PL Stat UDCTop-50 FP + ++ + + + - +Top-50 ICC$ + + + ++ +++ - - -Top-50 NM + ++ + + ++ - -Top-50 TPI + + + + + 0 ++Industry Avg 0 0 0 0 0 0 0

Page 16: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

New Indexes from CDN• Revised LPI

– 40% Production, 40% Type, 20% Fitness• New index called Pro$

– Index focused on commercial producers– Formulated based on traits most correlated

to profit generated through first 6 lactations using a DHI profit function.

– Less production, less %’s, less type, more health and fertility.

Page 17: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

Sire Ranking with new LPI

Page 18: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

Sire Ranking with Pro$

Page 19: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

A2 Milk

• Beta casein makes up about 30% of the protein in cow’s milk.

• There are 13 known genetic variations of the beta casein protein.

• A1 and A2 are the most common variants.• When humans digest A1 milk we produce

metabolites the may cause “problems”.

Page 20: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

Bull Genotypes

• Animals have 2 sets of chromosomes so they will have 2 genes that determine the type of beta casein they produce.

• Cows with 1 A1 gene and 1 A2 gene will produce milk with a mixture of A1 and A2 beta casein protein.

• Cows that produce no A1 beta casein protein are “preferred” (A2A2 genotype).

Page 21: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

a2 Milk Company

• The a2 Milk Company is now marketing a2 milk in the western US.

• Also being marketed in New Zealand, Australia, UK and China.

• The claim is that a2 milk will reduce the digestive discomfort that some experience when consuming milk.

Page 22: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

New Testing for Bulls

• Routine test only identifies the A1 variant from all others.

• The a2 Milk Company has a more specific test that will identify a bull’s specific genotype.

• In the future we may see genotypes like A3, A4, B, C, D, etc.

• Bulls that are confirmed to be true A2A2 will be identified in future sire summaries.

Page 23: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

Holstein TPI Trend(All Major AI Organizations)

200620072008200920102011201220132014201520161400

1600

1800

2000

2200

2400

2600

2800

3000

15151584

16841728

1885

2006

2112

2273

2381

16201700

17901841

1979

2115

2214

23582447

17291795

18851950

2073

2208

2304

24322510

2177

2322

2517

2365

26132526

26512691

2749

25th %ile Median Linear (Median)

Birth Year

More Rapid Genetic progress

Page 24: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

Jersey JPI Trend(All AI Organizations)

2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016-50

0

50

100

150

200

250

300

-25 -25

317

6270

103

129141

7 14

42 45

94 98

130147

161

3947

7482

123 117

153168

178

140157

193

162

242

185

234 238 245

25th %ile Median Linear (Median)

Birth Year

Page 25: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

Graduates by gTPI Decile 2009%ile Rank # of Graduates Graduation Rate

90 14 43.8%

80 6 18.2%

70 4 12.1%

60 1 3.0%

50 2 6.1%

40 1 3.0%

30 3 9.1%

20 0 0

10 0 0

0 0 0

329 B&W PGA-sampled Holsteins

Cheerio

P MartyMizzouMcfly

Page 26: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

Graduates by gTPI Decile 2010%ile Rank # of Graduates Graduation Rate

90 13 43.3%

80 7 22.6%

70 3 9.7%

60 3 10.0%

50 1 3.2%

40 2 6.4%

30 1 3.3%

20 2 6.4%

10 0 0%

0 1 3.2%

307 B&W PGA-sampled Holsteins

Sabathia

Gerry, Tiago

Montney

Page 27: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

Graduates by gTPI Decile 2011%ile Rank # of Graduates Graduation Rate

90 11 45.8%

80 3 12.5%

70 2 8.0%

60 2 8.3%

50 2 8.0%

40 3 12.5%

30 2 8.3%

20 0 0%

10 0 0%

0 2 8.0%

244 B&W PGA-sampled Holsteins

DraperBrokaw

TalbotBrickFangBradnickKennard

Page 28: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

Calving Ease Genomic Evaluations

• Compared April ‘14 to April ‘15 CE evaluations for genomic young sires.

• Average change going from 0 calvings to >200 was +0.3.

Number of Calvings % that go up >0.5

% that go up >1.0

< 50 calvings 35% 17%200 to 400 calvings 16% 3%

Page 29: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

PTA Changes for PGA bulls sampled in 2010 (286 bulls – August 2011 to April 2015)

PercentileRank

Ave TPI Change

Ave endingTPI % Rank

Ave NM$Change

Ave endingNM$ Rank

90 -200 85 -140 89

80 -171 73 -118 78

70 -185 61 -136 63

60 -164 58 -126 60

50 -167 47 -122 50

40 -126 49 -115 45

30 -145 37 -107 38

20 -95 40 -92 33

10 -111 26 -79 27

0 -70 20 -65 13

Page 30: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

-800

-600

-400

-200

0

200

400

Holstein Young Sires - Change in TPI

-800

-600

-400

-200

0

200

400

Holstein Proven Sires - Change in TPIComparison of change for the Top 100 Holstein Proven Sires for TPI and the Top 100 Holstein Young Sires for TPI in Apr 2011 with their TPI for Apr 2015

Average Change -237 TPI+199 to -723

Average Change -45 TPI+228 to -448

Page 31: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

Holstein Active AI – TPI Comparison

Apr. 11 Apr. 151700

1800

1900

2000

2100

2200

2300

19911946

2271

2034

Avg. TPI - Top 100 Proven Sires

Avg. TPI - Top 100 Young Sires

Page 32: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

Average change of -33 JPI(+33 to -98)

Average change of -51 JPI(+38 to -149)

Comparison of change for the Top 50 Jersey Proven Sires for JPI and the Top 50 Jersey Young Sires for JPI in April 2011 with their JPI for April 2015

-200

-150

-100

-50

0

50

Jersey Proven Sires - Change in JPI

-200

-150

-100

-50

0

50

Jersey Young Sires - Change in TPI

Page 33: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

Jersey Active A.I. - JPI Comparison

Apr-11 Apr-150

25

50

75

100

125

150

94

61

138

87

Avg JPI: Top 50 JPI Proven Sires

Avg JPI: Top 50 JPI Young Sires

Page 34: Genetic Evaluation and Index Changes. HA-USA Fertility Index Fertility Index =.64 x PTA Daughter Pregnancy Rate (DPR).18 x PTA Cow Conception Rate (CCR).18

Thank You!

Email: [email protected]: www.selectsires.com