h-TERT cell line

An hTERT cell line is one that has been immortalized by inserting the hTERT (human telomerase reverse transcriptase) gene into the cells' DNA. This gene immortalizes cells by maintaining telomere ends. This prevents the telomere shortening of a cell's DNA which would otherwise cause the cells to senesce.

Recurrent SETBP1 mutations in childhood Acute myeloid

Leukemia

Nature Genet-ics

Nature Genet-ics

Primer name Primer sequences(5'-3')SETBP1-forward CCACTTTCAACACAGTTAGGTG SETBP1-Reverse TCTCGTGGTAGAAGGTGTAACTC

Amino acid number 778~979

Nature Genet-ics

C2903 (ser869)

C2903T/C (ser869)Patient No.44

Tumor type Number of samples Number of mutated samples

Percent mu-tated samples

childhood AML 55 0 0