hcist 2013 dm
DESCRIPTION
Ontology developed for automatic acquisition and QA from Controlled Natural Language medical reportsTRANSCRIPT
Ontology based clinical practice justification in Natural Language
Presenters
David Mendes (PhD Student at Universidade de Évora)
Irene Rodrigues (PhD Advisor)
Departamento de Informática da
Universidade de Évora CENTRIA – Centre for Artificial Intelligence of UNL
Co-authors
Carlos Fernandes Baeta Unidade Local de Saúde do Norte Alentejano
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Agenda
The research activities Ontology Proposal Acquisition Flowchart Clinical Advising ? Example Conclusions
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HCist 2012 Background Ontology Proposal
OGCP* was introduced with appropriate characteristics for adequate reasoning and alignment with Well Founded Standards
Automatic acquisition (population) is compulsory given that the size of the available data residing in EHRs renders manual curating impossible
Knowledge Base Enrichment was developed Automatic clinical concept acquisition tools are used for the automatic
population of OGCP The resulting KB is sound in the underlying foundation of disease theory
due to the round trip, debug and repair enrichment method.
* Ontology for General Clinical Practice
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OGCP as target
Use the Basic Formal Ontology (BFO) as an upper-level ontology as support for Ontological Realism.
Is built upon 10 ontologies aligned according to the OBO Foundry principles (RO,FMA, SO, VSO, DO, Time, CVDO, OGMS,CPR)
Provides a formal theory of Cardio Vascular disease.
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Acquisition Flowchart
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Round trip debug and repair DC* usage of pragmatics for NLP acquiring from
SOAP reports in ULSNA+
Insertion of facts and automatic consistency validation using distributed Consequence Based reasoners (elk).
If inconsistent, the fact is redrawn The facts are generated in CNL# fashion Inferred axioms are built by the DC and valid by
nature
* Discourse Controller + Unidade Local de Saúde do Norte Alentejano # Controlled Natural Language
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Clinical Advising ?
The decision of what inferred knowledge is presented, with its justifications, to the user is a task handled by the DC using the developed pragmatics introduced by our Colleague Dora Melo.
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CNL Example Q: What is the patient´s personal history? A: Hypertension for 15 years; Diabetes Mellitus type 2 for
10 years; Cholecystectomy 2 years ago; Diabetic father; Obese BMI 26,5; Abdominal perimeter 106 cm.
Q: What is the suggested diagnosis? A: Laboratory routines: lipid profile; HgA1c; Rx thorax; ECG
in rest; Echocardiogram; Effort test (Effort proof or Cardiac scintigraphy);
Q: What is the immediate recommended therapy assuming that AHT and Diabetes are not controlled ?
A: Rich fiber and vegetable diet; polifraccionate and hiposaline; IECA or ARA II; Calcium Antagonist; Metformine; Estatine;
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Conclusions
We developed a knowledge representation infrastructure enabling the usage of highly optimized distributed consequence based reasoners that are referred in literature only in 2011.
It is imperative, for the broad acceptance of these tooling by the medical community, that the inferences are justified using CNL and adequate terminology.
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Thank you very much !!
Questions ?
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