healthcare - mirae asset...pharmaceutical and biotechnology verticals. advancements in therapeutics...

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Aging populations of the world should continue to drive opportuni- ties in healthcare One of the most significant and well recognized macro trends that is of particular importance to healthcare is the aging populations of the world. This phenomenon is relevant both to countries in developed markets as well as their counterparts in emerging markets. In the U.S., the dependency ratio will likely overtake the rest of the world in 2020, E VEN AS THE HEALTHCARE SECTOR has rounded out a fourth consecutive year of outperformance in 2014, we are confident that the sector is poised to continue to be an attractive investment option in 2015 and beyond. Our belief is supported both by macro trends that we feel will continue to bolster the sector in the coming years, as well as sector-specific issues that should provide a tailwind moving forward. Healthcare in focus 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 0 200 400 600 800 1,000 1,200 0 10 20 30 40 50 60 70 80 90 Source: United Nations, 2014. Dependency 65+ 0-14 15-64 % Population (million) Figure 2: China Age Demographics, 2010-2100. 2010 Population (million) 2020 2030 2040 2050 2060 2070 2080 2090 2100 0 50 100 150 200 250 300 0 10 20 30 40 50 60 70 80 90 Source: United Nations, 2014. Dependency 65+ 0-14 15-64 % Figure 1: U.S. Age Demographics, 2010-2100. showing a steep increase between 2010 and 2030 (Figure 1). Moreover, the number of people aged 65+ is poised to exceed the number of young people (aged 0 to 14) beginning 2030. The situation in China is even more dramatic, in part due to the country’s one-child policy, where the dependency ratio will likely overtake the rest of the world in 2040, and the number of people aged 65+ will exceed the number of young people 0 to 14 from 2030 (Figure 2). Dependency Ratio (%) (LHS) (LHS) (LHS) (LHS) (LHS) (LHS) (RHS) (RHS) Ratio Ratio Dependency Ratio (%) Equity Investment Team; Mirae Asset Global Investments (USA)

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Page 1: Healthcare - Mirae Asset...pharmaceutical and biotechnology verticals. Advancements in therapeutics that treat serious diseases, alleviate suffering, and improve overall quality of

Aging populations of the world should continue to drive opportuni-ties in healthcareOne of the most significant and well recognized macro trends that is of particular importance to healthcare is the aging populations of the world. This phenomenon is relevant both to countries in developed markets as well as their counterparts in emerging markets. In the U.S., the dependency ratio will likely overtake the rest of the world in 2020,

EVEN AS THE HEALTHCARE SECTOR has rounded out a fourth consecutive

year of outperformance in 2014, we are confident that the sector is poised

to continue to be an attractive investment option in 2015 and beyond. Our belief is

supported both by macro trends that we feel will continue to bolster the sector in

the coming years, as well as sector-specific issues that should provide a tailwind

moving forward.

Healthcarein focus

20102020

20302040

20502060

20702080

20902100

0

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1,000

1,200

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90

Source: United Nations, 2014.

Dependency65+0-14 15-64

%

Popu

latio

n (m

illio

n)

Figure 2: China Age Demographics, 2010-2100.

2010

Pop

ulat

ion

(mill

ion)

2020

2030

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2100

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Source: United Nations, 2014.

Dependency65+0-14 15-64

%

Figure 1: U.S. Age Demographics, 2010-2100.

showing a steep increase between 2010 and 2030 (Figure 1). Moreover, the number of people aged 65+ is poised to exceed the number of young people (aged 0 to 14) beginning 2030. The situation in China is even more dramatic, in part due to the country’s one-child policy, where the dependency ratio will likely overtake the rest of the world in 2040, and the number of people aged 65+ will exceed the number of young people 0 to 14 from 2030 (Figure 2).

De

pe

nd

en

cy

Ra

tio

(%)

(LHS) (LHS)(LHS) (LHS)(LHS) (LHS)(RHS) (RHS)Ratio Ratio

De

pe

nd

en

cy

Ra

tio

(%)

Equity Investment Team; Mirae Asset Global Investments (USA)

Page 2: Healthcare - Mirae Asset...pharmaceutical and biotechnology verticals. Advancements in therapeutics that treat serious diseases, alleviate suffering, and improve overall quality of

PAGE 2

Healthcarein focus

It is clear that as the world’s population ages, so grows the patient population that requires treatments and services that healthcare companies provide. This shift in demographics is also accompa-nied by a wealth disparity between the older and younger generations. In particular, we point to the U.S., where the wealth gap of the population age 65+ is several times that of the group aged

34-44 (Figure 3). Further, the overall wealth of the older population continues to increase on a yearly basis, as is shown for the years 2000-2011 in Figure 3. Indeed, we interpret these data to mean that, from a broad per-spective, the group of people who are in greatest need of healthcare, i.e., the group aged 65+, also has the means to pay for this care.

0

100

200

300

400

500

600

Ages 3

5-44

Ages 6

5-69

Ages 7

0-74

Ages 7

5+

Source: U.S Census Bureau, 2014.

%

2000 2011

Figure 3: U.S. Relative Wealth Gap, 2000-2011.

It is clear that as the world’s population ages, so grows the patient population that requires treatments and services that healthcare compa-nies provide.

Mar

199

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Mar

199

6

Mar

199

9

Mar

200

2

Mar

200

5

Mar

200

8

Mar

201

1

Mar

201

4

Source: Bureau of Labor Statistics, 2014.

Healthcare Employees (Quarterly Change) Total Employees (Excluding Healthcare)

-3,000

-2,500

-2,000

-1,500

-1,000

-500

0

500

1,000

1,500

Figure 4: U.S. Non-farm Payrolls Since 1990.

0

20,000

40,000

60,000

80,000

100,000

120,000

140,000

160,000

180,000

200,000

35 to 44 years 65 to 69 years 70 to 74 years 75 and over2000 2011

Median Household Net Worth (USD)

Thousands

Med

ian

Ho

use

ho

ld N

et W

ort

h (U

SD

)

Th

ou

san

ds

Page 3: Healthcare - Mirae Asset...pharmaceutical and biotechnology verticals. Advancements in therapeutics that treat serious diseases, alleviate suffering, and improve overall quality of

PAGE 3

Healthcarein focus

Healthcare companies continue to invest in workers to expand their businessThe strength of the healthcare sector is also reflected in employment statistics. To that point, the U.S. healthcare industry has not experienced a single quarterly decrease in the number of employees since 1990 (Figure 4). Additionally, the proportion of healthcare employees compared to the total number of employ-ees in the U.S. has continued to grow from 1990 until today, increasing from 8% to 13% (Figure 5). On a worldwide basis, the healthcare sector is now the fourth-

Jan

1990

Jan

1993

Jan

1996

Jan

1999

Jan

2002

Jan

2005

Jan

2008

Jan

2011

Jan

2014

8

9

10

11

12

13

14

Source: Bureau of Labor Statistics, 2014.

%

Figure 5: U.S. Healthcare Employees as a Percentageof Total U.S. Employees.

0

5

10

15

20

25

30

35

40

45

50

2007

2008

2009

2010

2011

2012

2013

2014

Source: Factset, 2014.

%

Healthcare IT Consumer Discretionary Consumer Staples

Figure 6: The Worldwide Healthcare Sector Continues to Grow Relative to Other Sectors.

largest sector, accounting for approx- imately 12% of the total as of 2014 (Figure 6). This has represented strong growth compared from 2007, when the sector represented 8% of the total and was only the eighth-largest sector.

We anticipate that these employment trends are likely to continue, as compa-nies look to capitalize on the growing demand in the marketplace, driven in part by the aging population and the means to pay for the healthcare that this population needs.

The proportion of healthcare employ-ees compared to the total number of employees in the U.S. has continued to grow from 1990 until today.

Page 4: Healthcare - Mirae Asset...pharmaceutical and biotechnology verticals. Advancements in therapeutics that treat serious diseases, alleviate suffering, and improve overall quality of

PAGE 4

Healthcarein focus

Strength of the therapeutics verticalsSome of the most exciting sub-sectors of healthcare in recent years have been the pharmaceutical and biotechnology verticals. Advancements in therapeutics that treat serious diseases, alleviate suffering, and improve overall quality of life of those suffering from various types of conditions have driven global drug spending. The five-year CAGR (Com-pound Annual Growth Rate)1 for global drug spending for the period of 2008-2013 was 4.5% (Figure 7), with total spending at nearly $1 trillion USD in 2013. On the heels of this expansion, growth is anticipated to accelerate further to 5.8% over the 2013-2018 timeframe, with global spending forecasts reaching $1.3 trillion USD by 2018. In our view, advancements in science and technology will pave the way for companies to develop ground-breaking therapies to improve the lives of those in need, and in so doing enjoy the rewards of their efforts.

We believe there will likely be ample scope for investors to capitalize on the continued growth and success of the

0

200

400

600

800

1,000

1,200

1,400

2008

2013

2018

Source: IMS Market Prognosis, 2014.

(USD Billion)

+195

+320

795

990

1,310

Figure 7: Global Spending on Therapeutics is Expected to Accelerate.

healthcare industry in markets around the world. While it is true that healthcare costs have increased significantly, and governments and healthcare systems are looking for ways to reduce this burden, there are incentives for companies that successfully innovate care – either in the service industry or the therapeutics space – to help to reduce overall health-care costs. Such innovators will be able to charge a premium for their services or products that improve patient outcomes and ultimately lower expenditure.

Emerging markets will play a critical role in healthcare investingWe anticipate that there will be significant opportunities for healthcare companies in emerging markets in the coming years. In addition to the aging population dynamic, growth will also be driven by the ever-increasing wealth of the populations in emerging markets. Moreover, as emerging markets governments continue to expand the scope of state-backed healthcare, companies domiciled both in developed markets as well as in the emerging market countries that serve these populations should be able to benefit.

Mirae Asset is uniquely positioned to capitalize on global healthcare trendsGiven our expertise in understanding the dynamics at play in the healthcare sector on a global scale and a team that works closely together while being spread over multiple regions, we believe Mirae Asset is uniquely positioned to adeptly manage a portfolio of healthcare stocks in both developed and emerging markets.

We believe there will be ample scope for investors to capitalize on the continued growth and success of the healthcare industry in markets around the world.

1The year-over-year growth rate of an investment over a specified period of time.

+195

CAGR4.5%

CAGR5.8%

+320

Page 5: Healthcare - Mirae Asset...pharmaceutical and biotechnology verticals. Advancements in therapeutics that treat serious diseases, alleviate suffering, and improve overall quality of

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PAGE 5