IBA

Gro

up

| IBA

L01/5049 | P

roto

n th

erapy 2016

REALIZING THE PROMISE OF PROTON THERAPYWe brought proton therapy to clinical cancer care. Ever since we started more than 30 years ago,

our collaborations, our visionary roadmap and progressively unrivalled experience have led us to innovate.

Care givers now benefit from leading, side-effect-minimizing, cost-effective proton therapy technologies.

Today, our complete range of Image-Guided IMPT* solutions can easily be integrated in most healthcare settings to make

it available to all patients who need it. Backed by IBA’s unique service offer (financing, workflow optimization, education),

our solutions range from the single-room Proteus®ONE to the tailor-made Proteus®PLUS. These are supported by robust

processes (installation, operations and upgrades) and are developed in collaboration with our endusers.

Tomorrow, our unique and open culture of sharing will further strengthen clinical and patient communities that we have

always cared for. As we work collectively we make proton therapy available to anyone who needs it.

We’re simply offering more cancer patients better quality of life.

AMERICAS

Toll-free: 1 877 IBA 4 PBT

T +1 904 491 6080

EUROPE, MIDDLE EAST AND AFRICA

T +32 10 203 342

F +32 10 475 923

E-mail: pone@iba-group.com

RUSSIA & CIS

T/F +7 495 648 69 00

E-mail: info@iba-russia.ru

ASIA PACIFIC

T +86 10 8080 9186

MORE INFORMATION: www.iba-protontherapy.com

THE INFORMATION CONTAINED IN THIS DOCUMENT IS PROPRIETARY AND CONFIDENTIAL. ANY USE AND/OR DISTRIBUTION OF THE MATERIAL CONTAINED HEREIN IS STRICTLY PROHIBITED WITHOUT THE WRITTEN PRIOR APPROVAL OF IBA. // THE MODEL PRESENTED IS A SIMPLIFIED MODEL FOR ILLUSTRATION PURPOSES ONLY. IBA SHALL NOT BE LIABLE FOR ANY DIRECT OR INDIRECT DAMAGE CAUSED BY THE UTILIZATION OF THE MODEL.// PROTEUSONE IS THE BRAND NAME OF THE PROTEUS 235 FDA CLEARED AND CE MARKED PRODUCT.

www.iba-protontherapy.com

HOW TO BUILD A PROTON THERAPY CENTER A GENERIC BUSINESS MODEL

www.iba-protontherapy.com

PROTON THERAPY MADE EASYProton therapy is widely accepted as a safe, effective and compassionate cancer treatment modality. It represents true progress in the battle against cancer. The right partner can help you break down a complicated process into a series of manageable steps. This partner can lead you along the way to bring this extraordinary treatment modality to your community.

Over the years, IBA helped its renowned clinical customers treat over 30,000 patients with proton

therapy. Those patients benefited from a more compassionate cancer treatment that ensured a better

quality of life during and after treatment.

IBA has installed over 50% of clinically operating proton therapy centers worldwide with over 30

projects that are already operational or at various stages of development. Leading institutions have

already chosen IBA. Join them to develop the future of cancer care together

With thirty years of experience in medical accelerators, IBA, the market leader, has designed

and equipped the majority of clinically operating proton therapy centers around the world.

You benefit from a learning curve that allows us to significantly reduce the time required to reach

first patient treatments.

30

30+

30,000+

YEARS OF EXPERIENCE

PROTON CENTERS PROJECTS DEVELOPED

PATIENTS TREATED

*Some features are under development and will be subject to review by competent authorities (FDA, Notified bodies, et al...)

ONE®Proteus

Proteus ®ONE*, COMPACT IMAGE-GUIDED IMPT SOLUTIONProteus®ONE is IBA’s compact single room proton therapy solution that can be integrated easily into many kinds of healthcare settings.

Much smaller and more affordable than conventional multi-room proton systems, but with the same clinical applications, Proteus®ONE makes proton therapy more accessible to clinical institutions worldwide and to their cancer patients.

TECHNICAL HIGHLIGHTS OF Proteus ®ONE*

Turning health care into human care

TYPICAL MEDICAL STAFF

ABOUT 7 FULL TIME EQUIVALENT PER ROOM PER 8-HOUR SHIFT

HOW TO BUILD A PROTON THERAPY CENTER ?

YEARLY OPERATIONAL EXPENDITURES (OPEX)

Clinical staff

Training of staff

Equipment operation & maintenance

Building maintenance & cleaning

Property insurance

General & administrative

Patients supplies

Power - equipment

FIXED OPEXCAPEX Proton Therapy equipment

OIS/TPS + dosi

Building

SOFT COSTS Development

Capitalized financial costs

Pre-operation & start-up expenses

VARIABLE OPEX

INITIAL INVESTMENT

THESE CHARTS ARE ILLUSTRATIVE ONLY AND VARY MARKET BY MARKET. WITH THE WORLD’S LARGEST INSTALLED BASE, WE HAVE EXPERTISE IN ALL MARKETS. WOULD YOU LIKE A PERSONALIZED BUSINESS CASE WITH DETAILED ESTIMATES FOR YOUR MARKET? CONTACT: PONE@IBA-GROUP.COM

TYPICAL CANCER INDICATION MIX % PATIENTS

HEAD & NECK 15%

BRAIN 10%

LUNG 15%

GENITOURINARY/ PROSTATE 15%

GASTROINTESTINAL 20%

OTHERS 5%

PEDIATRIC 15%

RETREATMENT 5%

TYPICAL SCHEDULE OF OPERATIONS

TOTAL NUMBER OF PATIENTS TREATED

PATIENTS TREATED* AT CAPACITY BETWEEN 300 AND 350 PER YEAR

NUMBER OF FRACTIONS* DELIVERED BETWEEN 35 AND 50 PER DAY * This information is highly dependent on the patient mix and

the schedule of operations.

250-275 DAYSper year

15 HOURSper day

HOURS OF OPERATION

DAYS OF OPERATION

0

20

40

60

80

100

120

0

20

40

60

80

100

120

STANDARD INSTALLATION PLANNING

1 2

BUILDING CONSTRUCTIONAPPROX. 12-18 MONTHS

3

APPROX. 12 MONTHS FROM EQUIPMENT INSTALLATION TO TREATMENT ROOM ACCEPTANCE

CLINICAL COMMISSIONING

4

1 PHYSICIAN1 DOSIMETRIST

1 PHYSICIST3 RADIATION THERAPISTS

1 NURSE

APPROX 7.6M/25FT

APPROX 19M/62FT

220° COMPACT GANTRY TREATMENT ROOM

TREATMENT CONTROL ROOM

CYCLOTRON AND BEAM TRANSPORT

SYSTEM