hyaluronic peptide serum - clinicalresolution.comclinicalresolution.com/main/pdf/post-procedure and...

Manufactured byClinical Resolution Laboratory, Inc.Brea, CA 92821

Hyaluronic Peptide Serum(Hydration, Firming and Lifting Effect)(1 fl. oz / 30 ml )

(877) 566-9687www.skincarecrl.comwww.clinicalresolution.cominfo@clinicalresolution.com

Naturally found in the skin, Hyaluronic Acid binds and attracts water to maintain skin softness and suppleness. This advanced serum delivers a nourishing boost to ensure the skin is adequately protected and hydrated, while providing soothing antioxidants to balance reddened, irritated, and sensitive skin. In combination with anti-aging multi-peptides and EGF, it helps to brighten the skin and fight wrinkles.

Key Features:• Absorbs quickly with a gentle, lightweight formula • Provides deep hydration • Increases skin firmness and elasticity• Softens fine lines and wrinkles while plumping the skin • Provides a silky, smooth skin texture • Helps minimize free radical damage • Provides an optimal level of antioxidants, nutrients, and vitamins• Good for all skin types

Key Ingredients:Sodium Hyaluronate: The most effective humectant for skin healing and regeneration. It provides hydration to the skin without depending on atmospheric moisture.

Acetyl Hexapeptide-8: Works through a unique mechanism that relaxes facial tension, leading to a reduction in superficial facial lines and wrinkles, with regular use.

EGF (Epidermal Growth Factor): Stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture.

Palmitoyl Tetrapeptide-7: Tightens and lifts the skin while containing messengers of cutaneous restructuration and repair. It activates the neosynthesis of extracellular matrix renewal and cell proliferation.

Myristoyl Hexapeptide-4 and Palmitoyl Tripeptide-37: Stabilized peptides, engineered for cutaneous delivery, that are resistant to enzyme degradation. It mimics TGF-ββ by activation of the transforming growth factor-ββ receptor Type II (TβRII) to activate collagen synthesis. Increased collagen production helps to reduce fine lines and wrinkles and improve skin tone and texture.

Vitamin B5: Reduces water loss in the skin. This suggests that topical vitamin B5, in various forms, is beneficial in improving skin form and function.

DMAE: A natural substance, known as ‘a facelift in a jar’, due to its amazing ability to dramatically tighten, firm, and tone neck and facial muscles, creating a leaner, more defined, and youthful look. It has the ability to strengthen and stabilize the cell’s plasma.

MAP (Magnesium Ascorbyl Phosphate): A vitamin C derivative that has better stability than ascorbic acid. MAP is often used for UV protection and repair, collagen production, skin lightening and brightening, and as an anti-inflammatory. It is also a potent antioxidant.

Ingredients: Sodium Hyaluronate, Aloe Vera Gel, Water, Dextran, Nonapeptide-1, Caulerpa Lentillifera Extract, Hydrolyzed Rice Protein, Acetyl Hexapeptide-8, Palmitoyl Tetrapeptide-7, Human Oligopeptide-1(EGF), Deionized Water, Vitamin B5, Dimethyl MEA, Palmitoyl Tripeptide-37, Myristoyl Hexapeptide-4, Propylene Glycol, Phenoxyethanol, Magnesium Ascorbyl Phosphate, Grapeseed Extract, Arbutin, Adenosine

Directions: Apply a dime-sized amount to the face and neck area. Gently massage into the skin until fully absorbed.

Caution: Avoid contact with eyes and mucous membranes. For external use only.


Liposomal Vitamin C Serum(Antioxidant Protection, Ultimate Collagen Booster and Tyrosinase Inhibitor)

(1 fl. oz / 30 ml )

Manufactured byClinical Resolution Laboratory, Inc.Brea, CA 92821 (877) 566-9687www.skincarecrl.comwww.clinicalresolution.cominfo@clinicalresolution.com

Key Features:

• Fights free radical damage for smooth, healthy skin

• Provides antioxidant protection and skin brightening benefits

• Defends against the sun’s harmful UVA and UVB rays

• Encourages collagen and elastin production to prevent fine lines and wrinkles

• Helps minimize dark spots and excess pigmentation on the face

• Formulated with 5%, 10%, 20% L-Ascorbic Acid (Vitamin C)

• Ideal for all skin types, including dry and sensitive

* Liposomal Vitamin C Serum, formulated with 5% Pure Vitamin C, can be applied under the eyes to diminish dark circles and puffiness while boosting collagen induction.

* Liposomal Vitamin C Serum, formulated with 10% and 20% Pure Vitamin C, gives your skin a triple boost, by stimulating collagen production, providing antioxidant protection, and exfoliating the skin to reveal healthier looking skin, while deeply penetrating to the dermal layer.

Key Ingredients: L-Ascorbic Acid: A powerful antioxidant, which uses a micro-delivery system to encourage collagen production, reverse photoaging, as well as lighten age spots and discoloration from scarring, sun damage, and freckles. It also helps to refine pore size and rebuilds collagen and elastin for firmer, younger looking skin. It is an essential cofactor for the synthesis of two enzymes (lysyl hydroxylase & prolyl 4-hydroxylase)which, in turn, catalyze the production of the amino acids required in order to produce collagen, which is the primary connective tissue in the skin.

Ingredients: Water, L-Ascorbic Acid, Ferulic Acid, Ethoxydiglycol, Glycerin, Ascorbic Acid 2-Glucoside, Sorbitol, Phenoxyethanol, Panthenol, Tocopherol, Sodium Hyaluronate, Triethanolamine

Directions: Cleanse skin thoroughly prior to application. Apply 5-7 drops of Liposomal Vitamin C Serum and gently massage with fingertips. It can be used alone, or layered under your moisturizer. In case of contact with the eyes, rinse thoroughly. As the formula blends into the skin, you may experience a feeling of warmth or a slight tingling sensation, which is normal.

Caution: Avoid contact with mucous membranes. For external use only. Store in a dark, cool place. Keep cap on tightly when not in use. Store at controlled room temperature between 15-30°C (59-86°F).

Advanced 247 Repair Serum(1 fl. oz e 30 ml)


Manufactured byClinical Resolution Laboratory, Inc.Brea, CA 92821 (877) 566-9687

Imagine a total skin recovery that works non-stop to rapidly repair damage and imperfections to bring back a youthful appearance. Advanced 247 (24 Hour 7 Day) Repair Serum is the ultimate age defying solution – a potent complex enriched with highly functional growth factors and advanced peptides to offer continuous repair and rejuvenation of aging skin.

Key Features: • Improves lipid barrier strength

• Accelerates the growth of epidermal cells

• Assists in wound healing

• Promotes healthier cell function

• Boosts collagen production

• Minimizes the appearance of fine lines and wrinkles

• Provides total reconditioning of the skin

• Hypoallergenic and ideal for hypersensitive skin

Key Ingredients: C10-30 Cholesterol/Lanosterol Ester: A medical grade lanolin with high purity that is used in the treatment of compromised skin conditions such as eczema and psoriasis.

Sodium Hyaluronate: Most effective humectant for skin healing and regeneration. It provides hydration to the skin without depending on atmospheric moisture.

sh-Decapeptide-9: Neuropeptides, commonly found in neural tissue, increase production of collagen, repair scars and wrinkles, and increase blood circulation to naturally reestablish radiance and glow to the skin.

Methylsilanetriol Aspartate Hydroxyproline: Provides firming, anti-aging, and anti-cellulite properties and helps expedite the healing process on small scars, while minimizing stretch marks and cellulite.

Palmitoyl Tripeptide-28: A stabilized peptide engineered for cutaneous delivery that is resistant to enzyme degradation and mimics TGF-β by activation of the transforming growth factor-ββ receptor Type II (TβRII) to activate collagen synthesis.

VEGF (Vascular Endothelial Growth Factor): VEGF induces endothelial cell proliferation and migration in the wound healing process.

PDGF (Platelet-Derived Growth Factor): One of the numerous growth factors, or proteins, that regulate cell growth and division. It allows unspecialized connective tissue cells, called fibroblasts, to divide and stimulate connective tissue cells and smooth muscle cells. These are then directed to divide at the wound site in order to repair the damaged area.

bFGF (Basic Fibroblast Growth Factor): Provides the initial stimulation of endothelial cell migration and proliferation in wound repair. It is also a potent mitogen for all cell types and found predominantly in the early proliferative phase of the wound.

Ingredients: Water, Betaglucan,1-2 Hexanediol, sh-Decapeptide-9, Glycerin, Methylsilanetriol Aspartate Hydroxyproline, Jellified Solution of Imperata Cylindrica (Root) Extract, Palmitoyl Tripeptide-28, C10-30 Cholesterol/Lanosterol Ester, Carthamus Tinctorius (Safflower) Oleosomes, Sodium Hyaluronate, Polyacrylamide, C13-14 Isoparaffin, Laureth-7, Neopentyl Glycol, Phenoxyethanol, Xanthan Gum, VEGF, PDGF, bFGF, Disodium EDTA, Grapeseed Extract Directions: On clean skin, apply a liberal amount onto the face and neck, AM and PM.


www.skincarecrl.comwww.clinicalresolution.cominfo@clinicalresolution.com


Premier Eye Defense Serum(1 fl. oz e 30 ml)

(877) 566-9687

This peptide and organic sea algae concentrate is a perfect combination of nature’s gift and technology at its best. Loaded with super ingredients that are rich in amino acids, proteins, antioxidants, and vitamins (including vitamin A, B, C, and E), Premier Eye Defense Serum provides a one-step solution to all signs of aging around the eye area – dark circles, puffiness, wrinkles, and eye bags.

Key Features: • Instantly hydrates and conditions the skin• Boosts collagen and elastin production• Provides enhanced delivery of caffeine to reduce the appearance of dark circles, crow’s feet, and fine lines• Reinforces firmness and tones the eye area• Decreases free radicals• Improves vascular circulation, promotes proper drainage of under eye fluid, prevents leakage of capillary fluid, reduces tissue damage • Helps soften the blue-red pigmentation in veins that are visible underneath the eyes• Gentle formulation that is suitable for sensitive and delicate skin

Key Ingredients: Liposomal Caffeine: An enhanced and controlled delivery of encapsulated caffeine, which increases microcirculation and fat metabolism to reduce swelling and bumpiness in the skin. The antioxidant properties of caffeine prevent the skin from extrinsic aging and help protect other actives in the formula. Caffeine is also useful for increasing photoprotection and treating atopic dermatitis.

Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7: Activates the elimination of blood originated pigments responsible for dark circles and local inflammation to tone and restore firmness to the eye area.

Ascophyllum Nodosum Extract, Asparagopsis Armata Extract: A highly potent cosmetic active ingredient that originates from the calibrated association of unique polysaccharides derived from two algae harvested in a pollutant-free environment. It normalizes the excessive increase in microcirculation caused by UV exposure to prevent premature aging, thus improving skin elasticity & resiliency.

Fucus Vesiculosus Extract: An exclusive extract from certified organic algae that reduces both dark circles and fine lines through a newly discovered pathway, HO-1. It stimulates the elimination of heme induced by blood leakage, which is responsible for dark circles and local inflammation.

Ruscus Aculeatus Root Extract, Ammonium Glycyrrhizate, Centella Asiatica Extract, Hydrolyzed Yeast Protein, Calendula Officinalis Flower Extract: A phyto-complex, rich in saponosides and flavonoids, helps to protect and reinforce the strength of blood capillaries and provides local soothing, anti-coupe rosé, and anti-dark circle benefits. It also boosts microcirculation to improve evenness of skin tone.

Ingredients: Water, Liposomal Caffeine, Butyrospermum Parkii (Shea Butter), Beeswax, Sodium Starch Octenylsuccinate, Hydroxyethyl Behenamidopropyl Bimonium Chloride, Polyquaternium-67, Hydrated Silica, Glycerin, Chrysin, N-Hydroxysuccinimide, Ascophyllum Nodosum Extract, Asparagopsis Armata Extract, Steareth-20, Chlorhexidine, Fucus Vesiculosus Extract, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Digluconate and Potassium Sorbate, Algae Extract, Ruscus Aculeatus Root Extract, Ammonium Glycyrrhizate, Centella Asiatica Extract, Hydrolyzed Yeast Protein, Calendula Officinalis Flower Extract, Hexylene Glycol, Caprylyl Glycol, Dimethicone, Xanthan Gum, Sodium Acrylates Copolymer, Lecithin, Ethylhexylglycerin, Disodium EDTA

Directions: Cleanse skin thoroughly prior to application and gently dab a dime-sized amount around the eye area with ring finger.



Revised 12.8.17Revised 12.21.17


Premier Spot Corrector Serum(1 fl. oz e 30 ml)

(877) 566-9687

The reduction of age spots and discoloration consists of decreasing melanin present in the skin by preventing its formation and diminishing its transport. Commonly known depigmentation substances, such as hydroquinone or kojic acid, are often overly sensitizing, unstable, or cytotoxic. These disadvantages have given CRL the challenge and foundation to develop this new specialized, target-specific serum.

Premier Spot Corrector Serum is an optimal brightening concentrate, super-charged with an exclusive selection of pigment stabilizing and anti-aging ingredients. It is carefully formulated to combat uneven skin tone, hyperpigmentation, and age spots but the most notable benefit is its ability to deliver results without causing skin irritation or side effects. It works mainly by inhibiting the maturation of melanosomes through the reduction of PMEL-17 gene expression and by deactivating tyrosinase, a copper-containing enzyme that catalyzes the formation of quinones from phenols and polyphenols (e.g. melanin from tyrosine), which causes skin discoloration. In essence, Premier Spot Corrector is the perfect choice for brightening the overall complexion to reveal more healthy and radiant skin.

Key Ingredients: Nonapeptide-1/Dextran: A respectable peptide produced synthetically through recombinant genetic technology that has the ability to reduce hyperpigmentation by inhibiting the action of tyrosinase in melanin-producing cells. First developed for its antimicrobial activities, it has since been found to be a strong inhibitor of melanin formation in laboratory studies of yeast and melanoma (skin cancer) cells. Nonapeptide-1 consists of the amino acids: arginine, lysine, methionine, phenylalanine, proline, tryptophan, and valine. It acts as a radiance promoter and whitening agent.

Alpha Arbutin: A natural skin lightening/whitening agent. It works by slowly releasing hydroquinone through hydrolysis, which in turn blocks tyrosinase activity and reduces the skin’s melanin production.

Caulerpa Lentillifera Extract: A green algae, also known as sea grape or green caviar, that is naturally found in the ocean. It strengthens the DEJ (dermal-epidermal junction) functionality by stimulating both laminin-5 and collagen IV, therefore improving skin cohesion and increasing exchanges between the epidermis and dermis. It also enriches and renews the extracellular matrix by increasing the synthesis of glycosaminoglycans (GAGs) and collagen. It refines the skin structure, firms and reduces saggy skin, and consequently delays the major signs of aging. Tetrahexyldecyl Ascorbate: A very stable, oil-soluble vitamin C ester which has antioxidant activity to inhibit lipid peroxidation. Topical use can mitigate the damaging effects of UV exposure. Studies have shown it to stimulate collagen production, while clarifying and brightening the skin by inhibiting melanogenesis (the production of pigment) to promote a more even skin tone.

Oil Soluble Licorice Extract: Inhibits pigmentation by preventing tyrosinase activation. Studies have shown that it can provide a considerable skin brightening effect while remaining non-toxic to melanin forming cells.

Pisum Sativum (PEA) Extract & Sucrose Dilaurate: A synergistic complex that offers a visible skin brightening effect by utilizing two pathways for melanin inhibition and is effective at reducing age spots and improving skin tone. Ingredients: Water, Glycerin, Glycyrrhiza Glabra (Licorice) Root Extract, Nonapeptide-1/Dextran, Alpha Arbutin, Caulerpa Lentillifera Extract, Hydrolyzed Rice Bran Protein, Caprylic/Capric Triglyceride, Neopentyl Glycol, C12-15 Alkyl Benzoate, Hydroxyethyl Cellulose, Tetrahexyldecyl Ascorbate, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Panthenol, Propylene Glycol, Xanthan Gum, Maltodextrin, Sucrose Dilaurate, Sodium Cocoyl Glutamate, Pisum Sativum (PEA) Extract, Polyacrylamide, C13-14 Isoparaffin, Laureth-7, Phenoxyethanol

Directions: Apply an appropriate amount to the area where age spots, melasma, hyperpigmentation, and non-laser related pigmentation can be seen.




VitaPep Serum (1 fl. oz e 30 ml)

VitaPep Serum is a powerful complex of nurturing vitamins and polypeptides that stabilizes the skin to reach its optimal moisture level and provides a complete defense against all signs of aging. It contains a significant amount of active ingredients to dramatically transform fatigued, dull, sagging, discolored, and aging skin to achieve a fully revitalized complexion. Restorative antioxidants also help build resilience and fight against environmental aggressors. This luxurious serum easily glides on the face and leaves your skin feeling hydrated, smooth, and radiant.

Key Features:• Stimulates cell replication and promotes collagen and elastin production• Prevents fine lines and wrinkles• Provides antioxidant protection• Helps even skin tone• Forms a breathable moisture barrier to create a smooth canvas for makeup application• Clinically proven to promote respiration and oxygen consumption at the cellular level• Improves fatigued and dull skin by accelerating cell turnover• Eliminates the visibly damaging effects of free-radical scavengers

Key Ingredients:Tetrahexyldecyl Ascorbate: A very stable, oil-soluble vitamin C ester, which has antioxidant properties that inhibit lipid peroxidation. Topical use can mitigate the damaging effects of UV exposure. Studies have shown it to stimulate collagen production, while balancing and brightening the skin, by inhibiting melanogenesis (the production of pigment).

Tocopherol: A fat soluble vitamin and antioxidant that helps to neutralize potentially damaging free radicals in the body.

Retinol: Helps renew skin plumpness, elasticity, and hydration to provide a radiant and fresh appearance. Stimulates skin cell proliferation, restoring thickness to thinning skin. These processes help fill in lines and wrinkles, while safeguarding skin from further wrinkle development.

Ascorbic Acid: A powerful antioxidant, which uses a micro-delivery system to encourage collagen production, reverse sun damage, as well as lighten age spots and discoloration to reveal a brighter and more even skin tone. It also helps to refine pore size and rebuild collagen and elastin for firmer, younger looking skin.

Magnesium Ascorbyl Phosphate: A vitamin C derivative that has better stability than ascorbic acid. MAP is often used for UV protection and repair, collagen production, skin lightening and brightening, and as an anti-inflammatory. It is also a potent antioxidant.

Hyaluronic Acid: The most effective humectant for skin healing and regeneration. It provides hydration to the skin without depending on atmospheric moisture.

Arbutin: A natural skin lightening agent. It works by slowly releasing hydroquinone through hydrolysis, which in turn blocks tyrosinase activity and reduces the skin’s melanin (pigment) production.

Matrixyl 3000: Contains messengers for cutaneous restructuration and repair. It activates the neosynthesis for extracellular matrix renewal and cell proliferation, while also lifting and firming the skin.

Ingredients: Cyclopentasiloxane, Dimethicone, Dimethicone/Vinyl Dimethicone Crosspolymer, Isododecane, Dimethicone/Cyclomethicone, Caprylic/Capric Triglyceride, Linoleic Acid, Glycine Soja (Soybean) Sterols, Phospholipids, Tetrahexyldecyl Ascorbate, Tocopherol, Retinol, Ascorbic Acid, Magnesium Ascorbyl Phosphate, Soluble Collagen, Hydrogenated Grapeseed Oil, Hyaluronic Acid, Arbutin, Matrixyl 3000

Directions: Apply one to two pump(s) of VitaPep Serum to cleansed skin, AM and PM. Follow with VitaPep Moisturizer.



VitaPep Moisturizer is a lightweight, skin renewal booster that is rich in vitamins, antioxidants, and amino polypeptides to encourage collagen production, cellular growth, and hydration. Invigorate your skin with the natural scent of citrus and feel the soothing and calming effects of the active ingredients working to fight free radicals and repair damage while also preventing future damage. Experience the noticeable difference in dull complexion and visible signs of aging.

Key Features:• Provides maximum hydration to maintain vitality of the skin• Boosts respiration and oxygen consumption at the cellular level• Promotes cell renewal• Accelerates skin cell turnover by 25% in just two weeks• Reduces wrinkles and the overall signs of aging• Provides antioxidant protection• Helps even skin tone• Results show dramatically younger, smoother looking skin • Recommended for normal to dry skin types

Key Ingredients:

Alpha Lipoic Acid: An extremely potent antioxidant that is both water and fat-soluble. Alpha Lipoic Acid helps vitamins C and E work better in the skin. It has anti-inflammatory qualities, which can be helpful in reducing the redness associated with rosacea, acne, and sensitive skin types. It reduces the appearance of wrinkles, fine lines, dull skin, puffy eyes, and dark circles.

Coenzyme Q10: CoQ10 is a powerful antioxidant that helps to repair sun damage. Compelling research has shown that CoQ10 effectively reduces wrinkles, age spots, and various signs of aging.

MSM (Methylsulfonylmethane): An organic source of biologic sulfur, MSM is a mineral that has numerous benefits for your skin. It has soothing and calming effects, is a collagen builder, and nourishes and clears all skin types. Sodium Hyaluronate: The most effective humectant for skin healing and regeneration. It provides hydration to the skin without depending on atmospheric moisture.

Magnesium Ascorbyl Phosphate: Fat soluble vitamin C that is extremely stable for use in skin care formulas, making it bio-available to the skin’s deeper layers. Fights free radicals and prevents damage as it repairs skin from sun, stress, and pollutants.

Polypeptide: Based on Lysine, Proline, and Glycine, it reduces the appearance of fine lines and wrinkles offering maximum hydration.

Ingredients: Water, Alpha Lipoic Acid, Aloe Barbadensis Leaf Extract, Persea Gratissima (Avocado) Oil, Simmondsia Chinensis (Jojoba) Seed Oil, Glyceryl Stearate, Sodium Hyaluronate, Saccharide Isomerate, Sodium PCA, Glycerin, Stearic Acid, Proline, Lysine, Lysine HCl, Carnitine, Arginine, Phenylalanine, Histidine, Tyrosine, Glycine, Amino Benzoic Acid, Dimethicone, Phospholipids/Sphingolipids/Cholesterol, Ammonium Stearate, 2-Hydroxyethyl Methacrylate, Tocopheryl Linoleate, Ammonium Lactate, Steareth-20, Lanolin, Magnesium Ascorbyl Phosphate, Ubiquinone (Coenzyme Q10), Methylsulfonylmethane, BHA, Adenosine

Directions: Apply one to two pump(s) of VitaPep Moisturizer to cleansed skin, AM and PM.



VitaPep Moisturizer(1 fl. oz e 30 g)


Revised 12.21.17


StemPep Serum (1 fl. oz e 30 ml)


A profound combination of patent pending stem cell technology combined with innovative active ingredients for the most natural and powerful anti-aging, wound healing, and skin brightening therapy.

StemPep Serum provides high concentrations of plant-derived stem cells and proteins to slow down the aging process by promoting healthy cell functions, synthesizing the cell renewal process, and by relinking the broken chains of amino acid bundles that make up collagen. It is highly recommended for post-procedure application following laser, IPL, microdermabrasion, and microneedling treatments.

Key Features:• Ideal for normal to oily and sensitive skin• Combats the signs of aging by protecting natural stem cells and delaying the aging of essential cells• Reduces the appearance of fine lines and wrinkles, while offering maximum hydration• Protects the vitality and youthful appearance of the skin• Nourishes and renews cells, thus keeping the skin firm and supple• Naturally boosts collagen production• Visibly younger looking skin in 2 weeks - 15% improvement after 30 days with continued use• Liposomal delivery transports plant stem cells to aging cells of the skin• Releases powerful antioxidants to fight free radicals

Key Ingredients: Malus Domestica Fruit Cell Culture Extract: Swiss apple stem cells are encapsulated in liposomes prepared from soy-phospholipids, which protects the longevity of the skin’s stem cells by delaying senescence of essential cells, combating chronological aging, and preserving the youthful look and vitality of the skin.

Hydrolyzed Pea Protein: Nano-sized liposomized peptides (~150nm) and stem cells extracted from peas help activate collagen production and fibroblast proliferation, while activating collagenase.

Human Oligopeptide-1: Highly effective for anti-aging, epidermal growth promotion, and wound healing.

Myristoyl Pentapeptide-8, Myristoyl Pentapeptide-11, Myristoyl Hexapeptide-4: Fibroblast growth factor gene stimulation for an anti-aging and whitening effect. These peptides show immune stimulation in vitro by upregulating primary defensin-B in human dermal keratinocytes. These polypeptides help promote protein stimulation (Collagen I) with minimal irritation (low matrix metalloproteinase, MMP1) and without elevating pro-inflammatory cytokines. Also, it stimulates Platelet-Derived Growth Factors (PDGF) and Vascular Endothelial Growth Factors (VEGF).

Herb Extracts: Provides an antioxidant, anti-inflammatory, and immunomodulatory effect which is effective in targeting atopic dermatitis, seborrhea, skin irritation, and whitening.

Ingredients: Deionized Water, Rhododendron Ferrugineum Leaf Cell Culture Extract, Malus Domestica Fruit Cell Culture Extract, Propanediol, C14-22 Alcohol and C12-20 Alkylglucoside, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, L-Ascorbic Acid, Magnesium Ascorbyl Phosphate, Alpha Arbutin, Cyclomethicone, Dimethicone, Sodium Hyaluronate, Panthenol, Human Oligopeptide-1, Hydrolyzed Wheat Protein, Hydrolyzed Pea Protein, Squalane, Ceramide 3, Myristoyl Pentapeptide-8, Myristoyl Pentapeptide-11, Myristoyl Hexapeptide-4, Glycyrrhiza Glabra Root Extract, Camellia Sinensis Leaf Extract, Rosmarinus Officinalis Leaf Extract, Centella Asiatica Extract, Ethylhexylglycerin

Directions: Apply one to two pump(s) of StemPep Serum to cleansed skin, AM and PM. Follow with StemPep Moisturizer.* Due to the presence of restorative stem cells and proteins, it is best to use at night.



StemPep Moisturizer(1 fl. oz e 30 g)


A profound combination of patent pending stem cell technology combined with innovative active ingredients for the most natural and powerful anti-aging, wound healing, and skin brightening therapy.

StemPep Moisturizer provides high concentrations of plant-derived stem cells and proteins to slow down the aging process by promoting healthy cell functions, synthesizing the cell renewal process, and by relinking the broken chains of amino acid bundles that make up collagen. It is highly recommended for post-procedure application following laser, IPL, microdermabrasion, and microneedling treatments.

Key Features:• Ideal for normal to dry and sensitive skin• Combats the signs of aging by protecting natural stem cells and delaying the aging of essential cells• Reduces the appearance of fine lines and wrinkles, while offering maximum hydration• Protects the vitality and youthful appearance of the skin• Nourishes and renews cells, thus keeping the skin firm and supple• Naturally boosts collagen production• Visibly younger looking skin in 2 weeks - 15% improvement after 30 days with continued use• Liposomal delivery transports plant stem cells to aging cells of the skin• Releases powerful antioxidants to fight free radicals

Key Ingredients: Malus Domestica Fruit Cell Culture Extract: Swiss apple stem cells are encapsulated in liposomes prepared from soy-phospholipids, which protects the longevity of the skin’s stem cells by delaying senescence of essential cells, combating chronological aging, and preserving the youthful look and vitality of the skin.

Hydrolyzed Pea Protein: Nano-sized liposomized peptides (~150nm) and stem cells extracted from peas help activate collagen production and fibroblast proliferation, while activating collagenase.

Human Oligopeptide-1: Highly effective for anti-aging, epidermal growth promotion, and wound healing.

Myristoyl Pentapeptide-8, Myristoyl Pentapeptide-11, Myristoyl Hexapeptide-4: Fibroblast Growth Factor Gene Stimulation for anti-aging and whitening effect. These peptides show immune stimulation in vitro by upregulating primary defensin-B in human dermal keratinocytes. These polypeptides help promote protein stimulation (Collagen I) with minimal irritation (low matrix metalloproteinase, MMP1) and without elevating pro-inflammatory cytokines. Also, it stimulates Platelet-Derived Growth Factors (PDGF) and Vascular Endothelial Growth Factors (VEGF).

Herb Extracts: Provides an antioxidant, anti-inflammatory, and immunomodulatory effect which is effective in targeting atopic dermatitis, seborrhea, skin irritation, and whitening.

Ingredients: Deionized Water, Rhododendron Ferrugineum Leaf Cell Culture Extract, Malus Domestica Fruit Cell Culture Extract, Propanediol, C14-22 Alcohol and C12-20 Alkylglucoside, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, L-Ascorbic Acid, Magnesium Ascorbyl Phosphate, Alpha Arbutin, Cyclomethicone, Dimethicone, Sodium Hyaluronate, Panthenol, Human Oligopeptide-1, Hydrolyzed Wheat Protein, Hydrolyzed Pea Protein, Squalane, Ceramide 3, Myristoyl Pentapeptide-8, Myristoyl Pentapeptide-11, Myristoyl Hexapeptide-4, Glycyrrhiza Glabra Root Extract, Camellia Sinensis Leaf Extract, Rosmarinus Officinalis Leaf Extract, Centella Asiatica Extract, Ethylhexylglycerin

Directions: Apply one to two pump(s) of StemPep Moisturizer to cleansed skin, AM and PM. * Due to the presence of restorative stem cells and proteins, it is best to use at night.



Revised 12.8.17

Age Defying Liposomal Retinol Serum(1 fl. oz e 30 ml)



Age Defying Liposomal Retinol Serum is an absolute youth recovery complex that is artfully formulated and prepared with specialized ingredients. It works on a molecular level to repair skin and stimulate collagen production to deliver firmer, smoother, and wrinkle-free skin, while increasing cellular turnover and blood vessel stimulation to restore the skin’s natural glow.

Key Features: • Unclogs pores to clear up blemishes, reduces blackheads, and minimizes pore size. Also helps prevent future breakouts by keeping dead skin cells from clogging pores

• Promotes skin cell proliferation

• Stops collagen breakdown from UV sun exposure

• Lightens sun spots, age spots, freckles, and pigmented scars

• Helps to neutralize free radical damage with time-releasing retinol technology

• Assists in reducing the formation of melanin, which is responsible for skin discoloration

• Improves the appearance of acne scars and reduces inflammation

Key Ingredients: Retinol: A derivative of vitamin A that works to unclog pores and enhance the effects of skin care actives by removing dead skin cells and increasing absorption. It also boosts collagen, accelerates cell turnover, improves skin firmness, and fights against environmental stressors.

Decapeptide-12: An oligopeptide made of twelve amino acids. It is primarily known for its ability to inhibit activity of the tyrosinase enzyme responsible for producing melanin.

Nicotinoyl Tripeptide-1: A skin cell stimulating tripeptide (GHK) conjugated with vitamin B3 (Nicotinoic Acid), which works as a strong antioxidant, anti-inflammatory, and cell detoxifying agent. It induces the reactivation of aged or damaged skin cells.

Nonapeptide-1/Dextran: A peptide produced synthetically through recombinant genetic technology that has the ability to reduce hyperpigmentation by inhibiting the action of tyrosinase in melanin-producing cells. It also has antimicrobial properties and acts as a radiance promoter and whitening agent.

Vitis Vinifera (Grape) Callus Culture Extract: Regulates free radical scavenging activities and helps the synthesis of collagen I by stimulating fibroblasts.

Resveratrol: Counters photoaging by inhibiting melanin synthesis. It also has antibacterial properties and controls sebaceous cell growth, while helping to reduce collagen loss and skin aging symptoms.

Ingredients: Water, Butylene Glycol, Dihydroxybenzylidene, Thiazolidinedione, Biostearyl Dimethicone, Glycerin, Dimethicone, Nonapeptide-1/Dextran, C12-15 Alkyl Benzoate, Dimethyl Isosorbide, Hydroxypinacolone Retinoate, Polysorbate 20, 1-2 Hexanediol, Decapeptide-12, Pyrus Malus (Apple) Fruit Extract, Resveratrol, Vitis Vinifera (Grape) Callus Culture Extract, Nicotinoyl Tripeptide-1, Cyclopentasiloxane, Caprylic/Capric Triglyceride, Palmitoyl Hexapeptide-14, Polymethylsilsesquioxane, HDI/Trimethylol Hexyllactone Crosspolymer, Glyceryl/Monostearate, Glyceryl Stearate/PEG 100 Stearate, PEG/PPG-18/18 Dimethicone, Cetearyl Alcohol, Carbomer, Triethanolamine

Directions: At night, apply a thin layer to clean face. Follow with Ultra Rich Cream for maximum anti-aging and brightening benefits.

Caution: Avoid contact with eyes and mucous membranes. For external use only. Reduce frequency if sensitivity occurs. Discontinue use if irritation persists.



Ultra Rich Cream(e 30g 1.0 fl.oz NET) Introducing CRL’s finest Ultra Rich Cream – a revolutionary skin moisturizer enriched with concentrated peptides in its purest form and EGF (Epidermal Growth Factor) derived from advanced recombinant protein technologies for high level protein expression.

Artfully created with deliberate care through every step of the process, Ultra Rich Cream offers a perfect balance of correction and prevention for aging skin. While the advanced peptides work to restore collagen, recombinant proteins encourage the skin’s innate ability to repair itself naturally.

• Long-lasting hydration and radiance• Instant boosting of skin firmness• Noticeable reduction of fine lines and wrinkles

Key Ingredients:

CRL’s Proprietary Blend: Twenty four plant-derived stem cell extracts effective for atopic dermatitis.

Caffeoyl sh-Octapeptide-4: Provides an anti-aging, anti-inflammatory, and antioxidant effect, while improving blood circulation. Nicotinoyl Tripeptide-1: Biomimetic peptides that brighten the skin, deliver anti-wrinkle benefits, and prevent atopic dermatitis. It is a strong antioxidant effective in reducing free radicals and inhibiting the aging of skin cells.

Nelumbo Nucifera Callus Culture Extract: Callus stem cell culture medium consisting of highly concentrated cytokine, which is effective for anti-inflammation, antioxidant, and anti-wrinkle benefits. It also provides a natural brightening effect.

Malus Domestica Fruit Cell Culture Extract: A patented liposomal preparation of apple stem cells derived from the ‘Uttwiler Spätlauber,’ a rare Swiss apple variety. It protects the longevity and increases the vitality of skin stem cells. It delays senescence of essential cells, and combats chronological aging.

Decapeptide-12: An oligopeptide made of twelve amino acids. It is primarily known for its ability to inhibit activity of the tyrosinase enzyme responsible for producing melanin.

Resveratrol, Thuja Orientalis Leaf Extract, Zanthoxylum Piperitum Fruit Extract: Biotechnologically engineered natural ingredients enriched with resveratrol. It protects skin from discoloration due to aging and UV exposure, while providing brightening and antioxidant benefits.

rh-Oligopeptide-1 (EGF): It enhances epidermal growth and keratinization while stimulating fibroblast to produce collagen.

Ingredients: Water, Glycerin, Stearoxymethicone/Dimethicone Copolymer, Methyltris (Trimethylsioloxy) Silane, Ceresin Wax, Dimethicone/Dimethicone PEG-10/15 Crosspolymer, Diphenyl Dimethicone/Vinyl Diphenyl Dimethicone/Silsesquioxane Crosspolymer, 1-2 Hexanediol, Caffeoyl sh-Octapeptide-4, Nicotinoyl Tripeptide-1, Decapeptide-12, Butylene Glycol, Water/Micrococcus Lysate/Ganoderma Lucidum, (Mushroom) Stem Extract/Serenoa Serrulata Fruit Extract, Diphenylsiloxy Phenyl Trimethicone/Dimethicone/Vinyl Dimethicone Crosspolymer, Triethylhexanoin, Ozokerite, Nelumbo Nucifera Callus Culture Extract, Malus Domestica Fruit Cell Culture Extract, Thuja Orientalis Leaf Extract, Zanthoxylum Piperitum Fruit Extract, Resveratrol, rh-Oligopeptide-1, Phenoxyethanol, Sodium Chloride, 1-2 Dihydroxydecane, 1-2 Decanediol, Allantoin, Azaleic Acid, Sodium Citrate, Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone

Directions: Apply a dime-size amount to cleansed skin, AM and PM.




Sun Protective Cream(DNA Repair with SPF 30)(1 fl. oz e 30 g)

Sun Protective Cream is a lightweight, hypoallergenic, chemical-free sunscreen that is formulated with an advanced silicone elastomer. Silicone elastomer compound provides a silky smooth feel upon application, and creates a breathable space between the skin and makeup.

Sun Protective Cream helps to repair not only damaged DNA due to UVA and UVB exposure, but also provides anti-aging benefits with the addition of a proprietary lipopeptide. Lipopeptide is shown in dermal cell culture studies to stimulate collagen and elastin production with minimal production of prostaglandins. Enjoy the benefits of a chemical-free sunscreen without the white, chalky effect that occurs with other chemical-free sunscreens.

Key Features:

• SPF 30+

• Recommended for all skin types

• Protection from UVA/UVB exposure

• Non-greasy and no white residue

• Safe to use after clinical procedures

• Can be used under makeup

• Contains a unique silicone elastomer

• No cytotoxicity, no product sensitivity

Key Ingredients:

Titanium Dioxide & Zinc Oxide: Natural ingredients that deflect harmful UV rays, rather than absorb them into the epidermis. Protects against both UVA and UVB rays (broad spectrum). In addition to sun protection, Titanium Dioxide offers a skin brightening effect, while Zinc Oxide stimulates skin cell regeneration and provides a soothing effect. Both are noncomedogenic, which means they do not contain oil that will clog pores.

Iron Oxide: A natural element that is non-toxic, non-irritating, and moisture resistant. One of the admirable qualities of Iron Oxide is that because it is moisture resistant, it provides a long-lasting effect upon application. It also works in conjunction with Titanium Dioxide and Zinc Oxide to boost the sun protection factor (SPF) and shield skin against visible light rays.

Myristoyl Hexapeptide-5: Repairs sun-damaged DNA cells, while helping with the production of collagen and elastin.

Ingredients: Titanium Dioxide, Zinc Oxide, Cyclopentasiloxane, Cyclomethicone, Dimethicone Crosspolymer, Iron Oxide Dimethicone/ Vinyl Dimethicone Crosspolymer, Tribehenin, Calcium Behenate, Sorbitan Isostearate, Alumina, Myristoyl Hexapeptide-5, PEG-10 Dimethicone, Methicone, Dimethiconol

Directions: Apply a dime-sized amount onto the face and neck every morning or before direct sun exposure.



hyaluronic peptide serum - clinicalresolution.comclinicalresolution.com/main/pdf/post-procedure and...

Documents