EMPOWERING HEALTHY AGEINGIFF Health’s natural solutions for ageing consumers

Cognitive

We support healthy living and healthy ageing in different ways

50m people worldwide are living with age-related cognitive disorders

PSA cognitive ingredient supported with FDA claims

According to WHO

Increase in demand for preventive strategies,

including supplementation

Experts predict that seniors will continue using dietary supplements

of the European population is 60 or older

Phosphatidylserine (PS) is a phospholipid and a natural building block in the brain, and plays an important role in cell-to-cell communication.

If urinary incontinence was a country, it would be the

third largest in the world

Less than 50% of people affected consult a physician, due to embarrassment or because they fear side effects

Medical treatments for incontinence (e.g. hormone substitution and surgery) can cause major disruption

High demand for non-medical/natural approaches to incontinence

It has been shown to:

A unique ingredient with FDA-approved qualified cognitive health claims*

*FDA. Phosphatidylserine and Cognitive Dysfunction and Dementia (Qualified Health Claim: Final Decision Letter ("https://wayback.archive-it.org/7993/20170111181614/http:/www.fda.gov/Food/IngredientsPackagingLabeling/LabelingNutrition/ucm072999.htm"http://www.fda.gov/Food/IngredientsPackagingLabeling/LabelingNutrition/ucm072999.htm (2003))

20%

people are affected by Cognitive Impairment

This number is expected to double over the next 20 years

30million

We offer a range of natural, science-backed ingredients to support healthy ageing.Let’s explore them...

Experts have called for action to address inevitable rises in cardiovascular, immune, urinary, bone & joint and cognitive disorders due to age

Immune Urinary Bone & jointCognitive Cardiovascular

Jaul E, Barron J.

Moloughney, S, Brain Health Market Trends: Supporting Cognition with Science‚ Nutraceuticals World, 6 December 2018

Nutrition Business Journal and American Botanical Council, 2017

Bone & joint

Immune

Cardiovascular

Cognitive

Urinary

Immune

Immune support represents one of the largest sectors of the global dietary supplement market, and was worth $14bn in 2017

The global herbal supplements market for immune health is predicted to grow from 2017 at a CAGR of 6.2% to 2027

CAGR of

6.2%

Echipower® may support the improvement of immunological

function

Fuji, F et al. ‘The Immunostimulating Effect by Ingestion of an Echinacea Purpurea Preparation’, Pharmacometrics 80 (5/6) 79-87, 2011

Echipower® may support the enhancement of immune function in

stressful conditions

EchinaceaProtection for life

Health benefit platforms

Nutrition Business Journal and American Botanical Council, 2017

The power of the flower

Empowering Healthy Ageing

Derived from a variety of sources, including

soy, sunflower and fish

Exclusive and patented grades

Excellent organoleptic properties - ideal for gummies & functional

foods

One of the leading phosphatidylserine brands

Cardiovascular

Immune support

$14bn2017

2027

people worldwide suffering from hypertension

The prevalence of cardiovascular disease increases with age – from 40% at the age of 40-59, to 70-75% between the ages of 60 and 79, and to 79-86% at 80+

Ageing arteries can be supported by dietary interventions such as the consumption of olive oil polyphenols

1.13 billion

Echinacea now represents the largest segment of the global immune health market, with a revenue share of around 35%

Echipower® is a unique product prepared from the cold pressed juice of the freshly harvested flowers of Echinacea purpurea

Complies with the monograph of the

European pharmacopeia

Can be used in different dietary

supplement applications

Supported by preclinical and clinical

studies

2011 Clinical study: Echinacea was found to significantly improve immunological vigour and other measures of immune function. It also resulted in a reduced sense of subjective stress response

Olive leavesan ancient solution backed by modern science

Offers a range of natural cardiovascular health support

Olive leaves have been used as a remedy for hypertension, inflammation, diabetes and atherosclerosis for thousands of years

World Health Organization, ‘Hypertension’ https://www.who.int/health-topics/hypertension/#tab=tab_1, Accessed 8 April, 2020World Health Organization, ‘Raised Cholesterol’, https://www.who.int/gho/ncd/risk_factors/cholesterol_text/en/ Accessed 8 April, 2020Yazdanyar A, Newman AB. ‘The burden of cardiovascular disease in the elderly: morbidity, mortality, and costs.’ Clin Geriatr Med. 2009;25(4):563–vii.

Revenue share

of 35%

In 2018 it was America’s second best-selling herbal supplement with sales totalling $110.3 Million

US sales

$110.3m

Bone & joint

Urinary

Improve memory

Improve mood

Reduce occasional daily stress

Support cognitive ability

deaths per year caused by raised cholesterol

2.6 million

40-59 60-79 80+

40%

70-75%79-86%

EFSA ‘Commission Regulation (EU) No. 432/2012 of 16 May 2012 Establishing a List of Permitted Health Claims Made on Foods, Other than Those Referring to the Reduction of Disease Risk and to Children’s Development and Health. Commission Regulation (EU) 2012Barbaro B et al. ‘Effects of the oil-derived polyphenol oleuropein on human health’ Int J Mol Sci, 15(10): 18508-24, 2014

National Institute on Aging ‘Urinary Incontinence in Older Adults’ https://www.nia.nih.gov/health/urinary-incontinence-older-adults,Accessed 8 April 2020

Hypertension

Inflammation

Atherosclerosis

Diabetes

Today, olive oil polyphenols such as oleuropein and hydroxytyrosol continue to be valued for their antioxidant and anti-inflammatory effects

Olive leaf extract with two key constituents – oleuropein and polyphenols – that act in synergy with other compounds to support cardiovascular health

Benolea® can support healthy blood pressure ranges, healthy cholesterol levels, healthy blood sugar levels, and coronary and vascular protection. It also offers a range of cholesterol-lowering effects

Benolea® is produced using EFLA®HyperPure technology which guarantees high purity and stability

Studies on oleuropein have revealed antithrombotic, antiatherogenic and vasodilatory properties

In Europe, EFSA has approved a claim that “olive oil polyphenols contribute to the protection of blood lipids from oxidative stress”

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Joint pain is widespread after middle age, yet most people suffering from it do not consult a physician. This is partly because it is seen as an inevitable aspect of ageing, about which little can be done

Curcumin is well known for its potent antioxidant and anti-inflammatory properties. It can play a vital role in the prevention of chronic inflammation which is linked to joint health

Formerly known as Frutarom Health, we have a long track record of meeting consumer demand for safe, scientifically substantiated and natural solutions

We offer a wealth of regulatory, application and formulation expertise, along with proprietary science, in-depth market knowledge and global capabilities

Now part of the IFF family, we are even better placed to help you gain a competitive edge in the dynamic health landscape

In a human clinical trial, NovaSOL® Curcumin has been shown to offer superior bioavailability to standard extracts

The limited bioavailability of curcumin is a major issue. Because of its low absorption and fast metabolization, very high dosages are needed to be effective

NovaSOL® solubilisation technology gives curcumin unique properties which overcome this problem, resulting in fast absorption and very highbioavailability. This enhances the multiple health benefits of curcumin, making it effective at much lower dosages

Go-Less® is a proprietary and clinically-backed formulation based on pumpkin seeds and soy isoflavones that provides natural, support for healthy bladder function

Go-Less® exerts a positive effect on the muscles by helping blood vessels relax and improving circulation. It may also affect the body’s hormones, helping strengthen the pelvic floor muscles and relax the bladder walls, which may support keeping the urethral wall elastic

Hydroxytyrosol

OHHO

HO

Oleuropein

HO O

OO

O

OO

HO

GLU

Pumpkin seedsTraditional phyto-therapeutics

Pumpkin seeds

Traditionally used by the Native Americans

to facilitate the passage of urine

You don't have to run run run, you can simply Go-Less®

The natural way to support men's urinary health

Cucurbita pepo L.have been an integral

part of European Herbal Medicine since 1539

Efficacy confirmed in clinical studies

Go-Less® Men is backed by published human clinical trials, all of which found the product effective for its studied use. In these studies, at least 78% of participants experienced significant improvements of BPH-associated symptoms, and which was also reflected in a significant improvement in quality of life

Go-Less® Men is an extract from an exclusive variety of defatted pumpkin seeds (Cucurbita pepo L.), processed using proprietary EFLA®HyperPure technology

Published human clinical trials demonstrate that Go-Less® Men can alleviate urinary symptom frequency and severity in men with BPH

Our proprietary EFLA® HyperPure technology allows the highly selective removal of contaminants, ensuring increased stability, solubility and absence of rancidity

Schiborr, C et al. ‘The oral bioavailability of curcumin from micronized powder and liquid micelles is significantly increased in healthy humans and differs between sexes’ Molecular Nutrition & Food Research (Volume 58, Issue 3, pages 516-527), 2014

Meeting the bioavailability challenge

Visit us atiff-health.com