INNOVATIVE 3D PRINTING APPLICATIONS FOR SURGICAL PLANNINGPROSPECTIVE AND CHARACTERIZATION STUDY

Author:

December 2017

WHAT IS 3D PRINTING?

• 3D printing is a manufacturing process in

which material is laid down, layer by layer, to

form a three-dimensional object.

• May employ a variety of materials (such as

plastic, metal, or other) and techniques

• Turn digital files containing three-dimensional

data - whether created on a computer-aided

design (CAD) or computer-aided

manufacturing (CAM) program or from a 3D

scanner - into physical objects.

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rce:

pix

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APPLICATIONS OF 3D PRINTING

Among many other, the top

applications are:

• Medical

• Aerospace

• Automotive

• Jewellery

• Food

MARKET

Global 3D Printing Market, by Applications, 2012 & 2019 (%) Adapted from Global 3D

Printing in Medical Applications Market, Transparency Market Research

17.0%

43.5%

21.5%

15.0%

2012

(EUR 1.8

billion)

17.2%

47.6%

19.6%

13.0%

Others Medical Automotive Aerospace Consumer Products

2019

(EUR 4.8 billion)

Top priorities related to 3D printing (%) Adapted from The State Of 3D Printing, Louis Columbus, Forbes, 2017

25

15

14

10

8

10

6

6

5

28

16

13

9

9

9

6

4

6

ACCELERATE PRODUCT DEVELOPMENT

OFFER CUSTOMIZED PRODUCTS AND LIMITED SERIES

INCREASE PRODUCTION FLEXIBILITY

BUYING A 3D PRINTER

ENABLING CO-CREATION

REDUCING TOOLING INVESTMENT

OOPTIMIZING DEMO PRODUCT EXPENSES

IMPROVING SPARE PARTS MANAGEMENT

OTHER

2017 2022

HEALTHCARE 3D PRINTING MARKET

The global 3D printing in medical

applications market is segregated

into various segments and sub

segments on the basis of

technologies, applications, raw

materials, and geography

Global 3D Printing in Medical Applications Markey Segmentation. Adapted from Global 3D Printing in

Medical Applications Market, Transparency Market Research

Global 3D printing market: drivers and restrains. Adapted from Global 3D Printing in Medical Applications

Market, Transparency Market Research

HEALTCARE APPLICATIONS – BIOPRINTING TISSUES AND ORGANS

• Organ printing takes advantage of 3D printing

technology to produce cells, biomaterials, and

cell-laden biomaterials individually or in

tandem, layer by layer, directly creating 3D

tissue-like structures

• Highly precise cell placement and high digital

control of speed, resolution, cell concentration,

drop volume, and diameter of printed cells

• Reduces the dependency on the short supply in

the organ donor market

A piece of a 3D printed ear cartilage. Adapted from qz.com

HEALTCARE APPLICATIONS –CUSTOMIZED IMPLANTS AND PROSTHESES

• Quickly produce custom implants and prostheses

• Implants and prostheses can be made in nearly any imaginable

geometry through the translation of x-ray, MRI, or CT scans into

digital 3D print files.

• Today, 99% of hearing aids that fit into the ear are custom-

made using 3D printing

HEALTCARE APPLICATIONS – 3D-PRINTED DRUGS

• The advantages include precise control of droplet

size and dose, high reproducibility, and the

ability to produce dosage forms with complex

drug-release profiles

• 3D printing technology will be very important in

the development of personalized medicine

• The first 3D printed drug, Sprintam

(levetiracetam, for epilepsy treatment), produced

and marketed by Aprecia Pharmaceuticals, has

obtained U.S. Food and Drug Administration

(FDA) approvalA tablet is formed by printing layers of polymer blended with drug. Adapted from pharmaceutical-journal.com

HEALTHCARE APPLICATIONS – 3D PRINTING OF MEDICAL DEVICES

• The number of 3D printed medical

devices is enormous and is growing

steadily

• The marketing of the 3D printed

titanium device FAST-FORWARD

BONE TETHER PLATE, which

facilitates less-invasive foot surgery

and eliminates the need to drill

through bone, has been approved

for use by the FDA.

HEALTCARE APPLICATIONS –ANATOMICAL MODELS FOR SURGICAL PLANNING

• The individual variances and complexities of the human

body make the use of 3D-printed models ideal for surgical

preparation

• The organs’ 3D printed replicas reproduce the size, weight

and texture of organs, allowing surgeons to rehearse

complicated procedures on 3D models

• Simulating all surgical steps in advance using prototype

models can help to foresee intra-operative complications,

which may result in reduced operating time and hence

allowing a cost-effective use of operating rooms

3D printed color model of a hearth. Adapted from forbesmiddleeast.com

HEALTCARE APPLICATIONS – TEACHING HEALTHCARE

• It is now well established the advantage

of using 3D-printed anatomical models

for teaching/training purposes

• 3D prints have the potential to be a

useful teaching tool for both anatomy

students and patients

• Many authors found a significant

improvement in students' overall scores

when using 3D printed model that

reduced the need to use cadavers

USE CASE – 3D PRINTING IN CARDIOVASCULAR SURGERY

3D Scan (CT, MRI, PET)

Adapted from pixabay.com

Adapted from grabcad.com

CAD model

Adapted from today.mims.com

3D model printing

Realistic 3D model for surgical planning

Adapted from 3Dprint.com