intergenic segments

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Page 1: Intergenic segments
Page 2: Intergenic segments

Also called intergenic regions, Any of the

DNA in between gene-coding DNA,

including untranslated regions, 5' and 3'

flanking regions, INTRONS, non-functional

pseudogenes, and non-functional

repetitive sequences. This DNA may or

may not encode regulatory functions

Introns: is any nucelotide sequence

within a gene that is removed by RNA

splicing which generate the final mature

RNA product of a gene

Page 3: Intergenic segments

The gaps or spaces between the genes that lie on chromosomes termed intergenicregions. By definition, intergenic regions are non-coding, (i.e., they are not transcribed into codons) and therefore do not direct the protein synthesis via messenger RNA(mRNA). Although not transcribed, intergenic regions have been shown to play a role in the expression of adjacent genes and there is increasing evidence that they contain important control sequences.

Page 4: Intergenic segments

Recent research suggests, however, that intergenic regions between genes may play critical roles in the process of imprinting, cancers and some birth defects. Current research projects are attempting to more accurately characterize the intergenic regions near imprinted genes that cause the expression of one parental allele over another

Page 5: Intergenic segments

Molecular biologist use sophisticated

mathematical techniques and modeling

enhanced with modern computer

technology (e.g. bioinformatic analysis) to

identify intergenic nucleotide sequences

and to investigate their potential role

in cell regulation. Sophisticated computer

algorithms may lead to a more detailed

understanding of the role intergenic regions

may play in gene regulation.