intro to endocrine. what do you know about these terms? membrane transport hormone negative and...
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Intro to Endocrine
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What do you know about these terms?
• Membrane• Transport• Hormone• Negative and positive feedback• Cholesterol• Membrane protein• phosopholipid• Selective Permeability• Cholesterol• Membrane protein• Hydrophilic• Hydrophobic
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Review of the Membrane
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Key Membrane Terms
• Phospholipid Molecule– Hydrophilic/hydrophobic (polar/non-polar)
• Cholesterol
• Membrane protein
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• Plasma Membrane: the outer boundary of a cell that encloses the cells contents.
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• Selective Permeability: some molecules are able to pass while others are not.
– Tea bags, colanders, plasma membranes(!!)
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• Hydrophilic: water loving
• Hydrophobic: fear of water
What kind of reaction occurs when you put a hydrophobic substance in water?– Think oil and vinegar
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Fluid Mosaic Model
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Three Parts to a Cell Membrane
• Phospholipid molecules – (formed into a phospholipid bilayer)
• Cholesterol molecule
• Membrane protein
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Phospholipid Molecule
Structure• Two fatty acids and one
phosphate head.• The fatty acids are
hydrophobic and the phosphate head is hydrophilic.
Function• The phospholipids
pair up, and form a bilayer with the fatty acids touching, and the phosphate heads facing outwards. This creates the cell membrane
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Phospholipid Molecule
Unsaturated fatty acidwhat’s this?
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Cholesterol Molecule
Structure• Rigid molecules
embedded in the lipid bi-layer
Function• Helps keep the
structure of the membrane and keeps the fatty acid tails anchored together.
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Cholesterol in Plasma Membrane
Where is the hydroxyl of the cholesterol?
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Membrane Proteins
Structure• Proteins are located
throughout the membrane (like raisins in a slice raisin bread)
Function• Regulation of what
passes through the membrane
• Serve as enzymes and take part in chemical reactions
• Act as markers that are recognized by chemicals in and out of the cell
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Membrane Proteins
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Passive Transport
• Diffusion
• Facilitated diffusion
• ligand-gated ion channel
• osmosis
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Active Transport
• http://programs.northlandcollege.edu/biology/Biology1111/animations/transport1.html
• proton pump
• Endo and exocytosis
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Steroid Signals
• http://highered.mcgraw-hill.com/sites/0072437316/student_view0/chapter47/animations.html#
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Protein Signals
• http://entochem.tamu.edu/G-Protein/index.html
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Intro to Endocrine/Negative Feedback
• http://health.howstuffworks.com/adam-200092.htm
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