jiang bian, ph.d. overview - cancer.ufl.edu · zhao, yue (phd student, ualr) li, yanyan (phd...

Jiang Bian, Ph.D. University of Florida

2197 Mowry Road, Room 122 PO Box 100177

Gainesville, FL 32610-0177 (501) 773 9074

[email protected] _____________________________________________________________________________________________

Overview Biomedical Informatics is an interdisciplinary field, where the central theme is to explore the effective uses of data, information, and knowledge for scientific inquiry, problem solving, and decision making, motived by efforts to import human health. I have a diverse yet strong multi-disciplinary background in data integration, semantic web, machine learning, natural language processing, social media analysis, network science, data privacy, and software engineering. Nevertheless, my expertise and background serve an overarching theme: data science with heterogeneous data, information and knowledge resources. My research areas can be divided into three logical sections under this overarching theme: (1) data-driven medicine—applications of informatics techniques, including machine learning methods in medicine on solving big data problems; (2) mining the Internet, including the social web, to provide insights into health-related behavior and health outcomes of various populations and finding ways to develop interventions that promote public and consumer health; and (3) development of novel informatics methods, tools and systems to support clinical and clinical research activities such as tools for data integration, clinical trial generalizability assessment, and cohort discovery.

Education

Ph.D. in Integrated Computing, University of Arkansas at Little Rock, Little Rock, Arkansas M.S. in Computer Science, University of Arkansas at Little Rock, Little Rock, Arkansas B.S. in Architectural Environment & Equipment Engineering, Tongji University, Shanghai, China

2010 2007 2005

Academic Appointments

Associate Professor (with Tenure) Health Outcomes & Biomedical Informatics University of Florida Gainesville, FL Assistant Professor Health Outcomes & Biomedical Informatics University of Florida Gainesville, FL Adjunct Graduate Faculty Computer Science University of Arkansas at Little Rock Little Rock, AR Assistant Professor Biomedical Informatics University of Arkansas for Medical Sciences Little Rock, AR

2019 – 2015 – 2019 2011 – 2015 2011 – 2015

Jiang Bian, Ph.D., July 2018 of 22

Professional Experience

Director of Cancer Informatics and eHealth Core University of Florida Health Cancer Center Gainesville, FL IT Research Manager Research Systems, Information Technology University of Arkansas for Medical Sciences Little Rock, AR Technical Lead/Lead Application Analyst Research Programs, Information Technology University of Arkansas for Medical Sciences Little Rock, AR

2018 – 2014 – 2015 2006 – 2014

Informatics Software and Systems

Project Title: OneFlorida Data Trust Project Description: The OneFlorida Data Trust is a unique data resource that contains linked electronic health records (EHRs), claims, and patient reported outcomes (PROs) data at the individual level, and covers 9 healthcare systems and 48% of Floridians (~10 million). Role: Faculty Lead Project Title: CLinicAl Research Administration (CLARA) Project Description: CLinicAl Research Administration (CLARA) is a web-based portal for submission, review, approval, and tracking of human subjects research in UAMS. Role: Project Team Lead

Project Title: Enterprise Image Repository (EIR) Project Description: The EIR is lightweight PACS alternative developed in-house in the UAMS to provide ubiquitous interfaces to effectively transmit, store, access, share, distribute and manage a variety of medical images produced through daily clinic activities. Role: Project Team Lead Project Title: Trauma Image Repository (TIR) Project Description: Built on the success of EIR in UAMS, the EIR has received a funding award from the Arkansas state trauma program to become the statewide medical image-sharing platform for trauma patients to allow sharing of critical images between unaffiliated emergency departments. The TIR program has over 167 participating sites around Arkansas and neighboring states. Role: Project Team Lead

2015 – 2010 – 2015 2007 – 2015 2008 – 2015

Professional Memberships and Activities

Memberships: Member, Association for Computing Machinery Member, Institute of Electrical and Electronics Engineers Member, American Medical Informatics Association Member, American Association for Cancer Research (400924) Editorial: Editorial Board, Journal of American Medical Informatics Open Guest Editor, Special Issue on Semantics-Powered Healthcare Engineering and Data Analytics, Journal of Healthcare Engineering Guest Editor, Special Issue on Security and Privacy for Healthcare

2010 - 2010 - 2012 - 2017 – 2018 2017 2017 –


Technologies, MDPI Journal of Cybersecurity and Privacy Associated Editor, BMC Medical Informatics and Decision Making (Impact Factor: 2.04) Associated Editor, MDPI Informatics (ISSN: 2227-9709) Associated Editor, American Journal of Science and Engineering (ISSN No.: 2159-6913) Associated Editor, Journal of Cyber Security and Mobility (ISSN: 2245-1439 (Print Version), ISSN: 2245-4578 (Online Version)) Conference and workshop organizer: Proceedings Chair, IEEE International Symposium on High Assurance Systems Engineering (HASE 2015, 2016) General Co-Chair, International Workshop on Semantics-Powered Data Analytics (SEPDA, 2016, 2017, 2018) Track Chair – Intelligent Systems and mHealth for Health Outcomes, Industrial and Engineering Applications of Artificial Intelligence and Expert Systems (IEA/AIE, 2017) Technical program committee: IMIA Yearbook of Medical Informatics (Cancer Informatics) 2018 IEEE Systems Conference (SysCon) 2013, 2014, 2015, 2016 IEEE International Conference on Healthcare Informatics (ICHI) 2013, 2014 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) 2013, 2014, 2015 AAAI Florida Artificial Intelligence Research Society Annual Conference—AI in Healthcare Informatics 2016 IEEE Conference on Connected Health: Applications, Systems and Engineering Technologies 2016 International Workshop on Service Assurance in System Wide Information Management (SASWIM) 2015, 2017 IEEE International Symposium on High Assurance Systems Engineering (HASE) 2017 International Conference on Health Information Science (HIS) 2016

Journal Reviewer: ACI: Applied Clinical Informatics (2011 – present) Journal of Biomedical Informatics – Elsevier (2010 – present) Journal of Health Informatics Research – Springer (2016 – present) PLOS One (2012 – present) Journal of Medical Internet Research (2015 – present) Computers and Electrical Engineering – Elsevier (2008 – present) Network Modeling Analysis in Health Informatics and Bioinformatics (2012 – present) Journal of Network and Systems Management – Springer (2009 – present) Journal of Network and Computer Applications – Elsevier (2011 – present) IEEE Transactions on Systems, Man, and Cybernetics, Part C: Applications & Reviews (2011 – 2012) IIE Transactions on Healthcare Systems Engineering – Taylor & Francis (2011) Transaction on Storage – ACM (2010 – 2012)

Conference Reviewer: AMIA Annual Symposium 2011—present AMIA Joint Summits on Translational Science 2012–present Annual IEEE Systems Conference 2013, 2014, 2015, 2016 IEEE International Conference on Healthcare Informatics 2013 IEEE International Conference on Bioinformatics and Biomedicine 2013 Security in Computers, Networking and Communication SCNC 2011 IEEE GLOBECOM 2011 IEEE International Conference on Communications (ICC) 2012 IEEE High-Assurance Systems Engineering (HASE) 2011—present Grant Reviewer/Study Section:

2017 – 2010 – 2012 –


NIH ZRG1 HDM-R (11) SBIR/STTR HDM Informatics (03/2014, 11/2018, 03/2019, 07/2019) ORAU Ralph Powe Award Program (2016) NSF Smart and Connected Health (02/2017) NIH Special Emphasis Panel ZRG1 PSE-H 50 (09/2017) NSF Secure and Trustworthy Cyberspace (04/2018) NSF Smart and Connected Community (05/2018)

Honors and Awards

Exemplary Teacher Award, College of Medicine, University of Florida Outstanding Ph.D. Graduate, College of Engineering and Information Technology, UALR Outstanding Ph.D. Student, Department of Computer Science, EIT, UALR caBIG Delivering Results Award, caBIG, NCI Most Promising Ph.D. Research Student Award, Department of Computer Science, EIT, UALR Most Promising Ph.D. Research Student Award, Department of Computer Science, EIT, UALR M.S. Academic Achievement Award, Department of Computer Science, EIT, UALR M.S. Service Achievement Award, Department of Computer Science, EIT, UALR

2016, 2017, 2018 2010 - 2011 2010 - 2011 July 21st, 2009 2008 – 2009 2007 – 2008 2006 – 2007 2006 – 2007

Educational Activities

Teaching: GMS 6806: Security and Privacy in Clinical Research Level: Graduate level Role: Course Director GMS 6803: Data Science for Clinical Research (UF) Level: Graduate level Role: Course Director

CPSC 7373: Artificial Intelligence (UALR) Level: Graduate level Role: Course Director BINF 5023: Semantic Web Technology – Using Semantic Web Technology in Biomedical Research (UAMS) Level: Graduate level Role: Course Director Advisor/Advising committees: Current Zhaoyi Chen (Mentor, Post-doc fellow, UF; 06/2019 - ) Hansi Zhang (Co-chair, PhD in Biomedical Informatics, UF) Xing He (Co-chair, PhD in Biomedical Informatics, UF) Yunpeng Zhao (Co-chair, PhD in Biomedical informatics, UF)

Spring 2018 Fall 2015, 2016, 2017 Fall 2012, Fall 2014 Spring 2015


Jae Min (Committee, PhD in Epidemiology, UF) Alexander Loiacono (Chair, MS in Biomedical Informatics, UF) Justin Tauscher (Chair, MS in Biomedical Informatics, UF) Past Juan Antonio LOSSIO-VENTURA (Mentor, Post-doc fellow, UF; 05/2016-05/2019) Tamara Macieira (Committee, PhD in Nursing, UF; 05/2019) Patel, Aditi (Committee, MD/PhD in Health Outcomes & Policy, UF; 06/2018) Matthew Diller (Committee, MS in Biomedical Informatics, UF; 08/2018) Sarvesh Soni (Committee, MS in Computer Science, UF; 05/2018) Jue Yang (Committee, MS in Geography, UF; 05/2018) Ahmed, Mubbasheer (Post-doc fellow, ACH) Zhou, Shujian (Post-doc fellow, UALR) Liang, Hao (PhD student, UALR) Zhao, Yue (PhD student, UALR) Li, Yanyan (PhD student, UALR) Liu, Xiao (MS student, UALR) Yang, Junshuang (MS student, UALR)

Grants and Contract Awards

Pending: PCORI (Wu, Bian) 10/01/2019 - 09/30/2022 NLP to Connect Social Determinants and Clinical Factors for Outcomes Research This project seeks to develop clinical natural language processing (NLP) methods and systems to extract and connect social and behavioral determinants of health (SDoH & BDoH), and adverse events (AEs) with clinical factors directly generated by clinical practice for health outcomes research. We will 1) systematically examine state-of-the-art NLP methods and develop new corpora and algorithms for SDoH, BDoH, and AEs, 2) explore automated learning methods to integrate medical knowledge with statistical NLP methods, 3) advance existing NLP methods to better handle clinical abbreviations in medical concepts, and 4) develop and disseminate an NLP package – SODA, which extracts, standardizes, and populates SDoH, BDoH, and AEs information (in addition to clinical factors) from clinical narratives Role: Principle Investigator (Dual PI) 1.2 calendar months NIH/NIA (Golde) 04/01/2020 - 03/31/2025 1Florida Alzheimer’s Disease Research Center A consortium of Florida institutions helping to change the current understanding of Alzheimer's disease and related dementias from being incurable, inevitable and largely untreatable to a new reality in which these diseases are curable, preventable and treatable. Role: Co-Investigator (Data Core) 0.60 calendar months NIH/NIMH (Patek, Bian) 12/01/2019- 11/30/2024 Linking VA and non-VA data to study the risk of suicide in chronic pain patients The proposed project addresses this critical need by integrating large-scale VA and non-VA data to study the risk of deaths (suicide and accidental opioid overdose), and suicidal ideation and attempts in Veterans on chronic opioid therapy (COT). Role: Co-Investigator (UF Site PI) 0.84 calendar months NIH/NCI (Huo, Bian) 01/01/2020 - 12/31/2023 The benefits and harms of lung cancer screening in Florida Lung cancer screening using Low-dose computed tomography is a promising


technique to reduce the burden of lung cancer, the leading cause of cancer-related death in the United States. Concerns over high false positives, invasive diagnostic procedures, postprocedural complications, and downstream health care costs impede developing and promoting lung cancer screening program. Our research is to leverage a large repository of linked electronic health record (EHR) and administrative claims data to understand contemporary use of lung cancer screening and the associated health care outcomes and costs in a real-world setting. Role: Principal Investigator (MPI) 1.80 calendar months Impact Score: 33 (14 percentile; ESI payline: 14 percentile) Ongoing Research Support: NIH/NIA 1 R21 AG061431-01 (He, Bian) 01/15/2019 - 11/30/2020 Systematic Analysis of Clinical Study Generalizability Assessment Methods with Informatics We propose first to systematically review the extant methods for generalizability assessments, and then use a data-driven strategy to reproduce, evaluate, and compare these methods with our unique data resource, the OneFlorida Data Trust. We aim to answer two key research questions: (1) whether the a prior generalizability can predict the actual clinical outcomes of the interventions on the target population; and (2) how the exclusion criteria that may limit older adults’ participation affect study generalizability and outcomes of patients in different age groups. We focus on breast, lung, and colorectal cancer trials. Role: Principal Investigator (MPI) 1.00 calendar months NSF SBE #1734134 (Prosperi, Bian, Zhou) 09/01/2017–08/31/2020 A Person-Centric Prediction Model of Job Loss based on Social Media Job loss marks a significant impact on an individual's personal and social life. In this research, a hybrid big data theory-based approach will be taken, using information derived from the popular social media Twitter, to create prediction models of job loss events. Two studies are devised: (1) Identify job loss predictors from micro, meso and macro perspectives in Twitter data by exploiting linguistic and sentiment analysis; (2) Analyze the job topic networks of Twitter users to infer network indices as predictors of job loss. Role: Co-Principal Investigator 1.00 calendar months NIH/NCATS 1U01TR001806-01 (Starren, Bian) 09/15/2016–09/14/2020 Improving Patient Reported Outcome Data for Research through seamless integration of the PROMIS Toolkit into EHR Workflows To achieve this, we will develop software to support tight integration into the two most common academic medical center EHRs--Epic and Cerner. We will develop a generalized integration of the PROMIS toolset, utilizing the SMART-on-FHIR standard, that can be implemented in multiple EHR platforms. Finally, we will implement and evaluate these software solutions across a number of diverse CTSA sites both within and outside of the project team CTSA sites. Role: Co-Investigator (UF Site PI) 2.40 calendar months NIH 1R01NR015988-01A1 (Perry, Bian) 07/20/2018–05/31/2023 Implementing a Guidelines-Based M-Health Intervention for High Risk Asthma Patients The overarching goal of the proposed project is to examine the effectiveness of a personalized, interactive asthma smarthphone application in reducing asthma morbidity among adolescents who are at increased risk for future asthma exacerbations. Further, we will examine the impact of sharing smartphone asthma-related data with the primary care provider (PCP) on outcomes. Role: Co-Investigator (UF Site PI) 1.20 calendar months PCRF #1239 (Shenkman) 10/1/2018–09/30/2020 PCORnet 2.0/PCRnet Clinical Research Network Infrastructure: OneFlorida Clinical Research Consortium This project is to develop further the research infrastructure in OneFlorida as part of PCORnet 2.0. OneFlorida is a Data Research Network that provides an


enduring infrastructure for comparative effectiveness research and pragmatic clinical trials. Role: Co-Investigator (Director of Query Coordination) 0.60 calendar months NIH/NIA P30AG028740 (Pahor) 4/1/2017 - 3/31/2022 University of Florida Calude D. Pepper Older Americans Independence Center (OAIC) The mission of the University of Florida Older Americans Independence Center (OAIC) is twofold: 1) to optimize older persons' physical performance and mobility through interdisciplinary approaches; and 2) to train new investigators in aging and disability research while developing their leadership qualities. Our goal is to enhance late-life health and independence, with a special focus on mobility. Role: Co-Investigator (DATA SCIENCE AND APPLIED TECHNOLOGY CORE (RC4)) 0.30 calendar NIH 9R01GM121081-05 (Gluech,Muller,Dabelea) 08/15/2016–06/30/2020 Methods and Software for Lifecourse Epidemiology Data and Sample Size Analysis Lifecourse epidemiology is the study of chronic disease risk associated with the long‐term effects of exposures occurring throughout the life course. When repeated measurements of risk factors over time are used to predict disease outcomes, the complex study designs require new data and sample size methods and software. We propose to create new methods and software for risk factor trajectories, and broadly disseminate them to a wide audience of scientists. Role: Co-Investigator (Informatics Lead) 1.20 calendar months FL DOH #9AZ14 (Maraganore) 02/01/2019–01/31/2021 Utilizing Data from the Electronic Medical Record to Predict Alzheimer's and Dementia Risk First, we will utilize data captured by the EMR at the University of Florida (UF), to develop a cognitive impairment/dementia/AD prediction model (UF AD prediction model). Second, we will replicate the model using historical data captured by the EMRs at OneFlorida Clinical Research Consortium sites. Third, we will integrate it into the UF EMR and build clinical decision support (CDS) tools that identify patients at highest risk for cognitive disorders and guide referral by primary care providers to brain health specialists. Role: Co-Investigator (EHR Integration Lead) 0.60 calendar months NIH/NCI 1R01CA234030-01A1 (Staras) 07/01/2019 - 06/30/2022 Text and Talk: A multi-level intervention to increase provider HPV vaccine recommendation efficacy The goal of this project is to evaluate the separate and synergistic effects of a multi-level intervention of provider-targeted brief trainings and parent-targeted interactive text messages on provider recommendation and HPV vaccination among 11- to 12-year-olds in primary care. Role: Co-Investigator (Informatics Lead) 0.90 calendar months PCORI PaCR-2017C2-8153 (Pletcher@UCSF, Cooper-DeHoff@UF) 04/01/2017 - 03/31/2022 Using PCORnet to Compare Blood Pressure Control Strategies The Health eHeart Alliance, American Heart Association (AHA), American Medical Association (AMA), and PCORnet Cardiovascular Health Collaborative Research Network propose to establish a PCORnet Blood Pressure Control Laboratory to generate real-world evidence with the goal of enhancing blood pressure (BP) control and cardiovascular health in the US. The BP Control Lab will enable BP control surveillance in PCORnet-affiliated institutions, provide feedback to healthcare systems and clinicians on achievement of BP control goals and process measures, and conduct efficient pragmatic comparative effectiveness research on interventions designed to enhance BP control.


Role: Co-Investigator (Informatics Lead) 0.60 calendar months US DOJ 2016-PM-BX-K005 (Delcher, Goldberger) 10/01/2016 - 09/30/2019 FL's Next Gen of Prescription Drug Related Surveillance: Data into Insights that Enhance PDMP Best Practices The University of Florida (UF), the PDMP and collaborators seek to address three major impact areas including: 1) increasing the analytic use of de-identified prescription data, 2) increasing the operational use of the PDMP by health care practitioners, and 3) establishing new collaborations among law enforcement, medical examiner and clinical sectors. Role: Co-Investigator 0.42 calendar months UFHCC Tobacco Pilot Bian/Huo 04/01/2018–10/31/2019 (NCE) Establishing Social Media-based Methods to Understand Lung Cancer Screening Behavior This project is relevant to public health because it determines the behavioral factors associated with the utilization of lung cancer screening that can result in population-level interventions to reduce lung cancer morbidity and mortality. Sparse knowledge exists regarding data mining approaches on massive social media data for collecting individuals’ behavioral factors on lung cancer screening among millions of social media users. Upon completion, our study will provide evidence on the application of innovative social media tools that can be adapted to other disease control and prevention settings. Role: Principal Investigator Completed: PCORI CDRN-1501-26692 (Shenkman, Hogan) 11/01/2015–04/01/2019 OneFlorida Clinical Research Consortium OneFlorida was created in 2009 by aligning diverse partners including patients, clinicians, health systems, researchers, payers of third-party claims, and state agencies in Florida. It provides an enduring infrastructure for research. OneFlorida includes 9 unique clinical systems that in 2014 provided care for approximately 10 million (48 percent) of all Floridians through 4,100 physicians, 1240 clinical practices, and 22 hospitals. Role: Co-Investigator (Director of Query Coordination) AHRQ U18HS025298 (Shenkman) 01/01/2017-12/31/2018 The Child Health Quality Partnership (CHeQ) Program The Child Health Quality Partnership will test the feasibility and usability of dental and mental-health related quality of care measures for children in two of the three largest states in the US. The Child Health Quality Partnership will test and implement new measures to assess the quality of care for children in Medicaid and the Children’s Health Insurance Program in Texas and Florida. Role: Co-Investigator NSF ACI (ACI1429160) (Xie) 09/01/2014 – 12/31/2018 MRI: Acquisition of Peta-Scale Data Storage System for Big Data Exploration in STEM Fields The project augments existing high performance computing capabilities, includes projects in different disciplines to be facilitated by cyber upgrades, provides integration of research and education through training opportunities for students at all levels, and has a potential for broadening participation of a diverse scientific workforce. Role: Co-Principal Investigator UFII Postdoc Award (Bian) 01/01/2018–12/31/2018 Building an obesity and cancer knowledge base and a web-based semantic search tool for accessing evidence-based online health information Role: Principal Investigator (Mentor; Postdoc: Lossio-Ventura JA) NIH/NCATS CTSA Pilot (Guo,Bian) 02/15/2017–02/14/2018 Developing a Facebook app to promote colorectal cancer screening: pilot


testing a social media intervention The goals of this project are to: 1) develop an evidence-based Facebook app that can collect patient-reported data, compute and deliver individualized CRC risks and health information, and provide CRC screening reminders and support referrals through access awareness, and 2) pilot test a Facebook-based social media intervention and evaluate its effect on increasing CRC knowledge, screening intention, and screening rate. Role: Co-Principal Investigator PCORI (Morris,Donahoo) 02/15/2017–02/14/2018 Diabetes Incidence Prevalence and Medications Use The project has 4 aims: 1. Describe patterns and trends in the use of major classes of glucose lowering medications for T2 diabetes over the past 3 years and establish a process for ongoing, semi-annual updates. 2. Provide a validation of the computable phenotype used for T2 diabetes and new onset T2 diabetes. 3. Adopt or develop and validate computable phenotypes for relevant complications of T2 diabetes and other relevant adverse effects of treatments. 4. Provide data on the capacity to follow patients with T2 diabetes longitudinally for the occurrence of outcomes. Role: Co-Investigator FL DOH: #4KB16 JEK (Shenkman) 2/27/2015 – 06/30/2017 OneFlorida Cancer Control Alliance The OneFlorida Clinical Research Consortium formed the OneFlorida Cancer Control Alliance to strengthen statewide infrastructure and reduce health disparities in cardiovascular disease and cancer related to tobacco use. The alliance will enhance the consortium’s infrastructure available to conduct tobacco-related cancer and cardiovascular disease research, particularly in primary care settings serving vulnerable populations. Role: Co-Investigator PCORI GEN-1607-35623 (Hogan) 11/01/2016-10/31/2017 Planning for congenital Zika syndrome surveillance in PCORnet and Sentinel The purpose of the project is to understand the most effective way to leverage the PCORnet and Sentinel infrastructures for EHR and claims data to enhance congenital Zika syndrome surveillance as well as to contribute data to help more clearly define it and understand its natural history. Role: Co-Investigator NIH/NHGRI U01HG007269 (Johnson) 10/01/2016-04/30/2017 Genomic Medicine Implementation: The Personalized Medicine Program (PMP) Administrative Supplement The aim of the project is to study whether CYP2C19 genotype influences therapeutic and adverse outcomes of proton pump inhibitors (PPIs). The hypothesis is that genotypes leading to poor CYP2C19 metabolism predispose to adverse events of PPIs, whereas genotypes leading to rapid CYP2C19 metabolism predispose to esophageal reflux disease that is refractory to PPI therapy. Role: Co-Investigator Texas HHSC 529-07-0093-00001G (Shenkman) 02/28/2015-12/01/2016 Evaluating Health Care Quality in Texas Medicaid and CHIP This study is designed to evaluate the quality of care, illness burden and health care expenditures for women and children enrolled in the managed care component of the Texas Medicaid Program or in the State Children’s Health Insurance Program. Role: Co-Investigator UL1TR000039 James (PI) National Center for Advancing Translational Sciences Total amount: $3,766,010.00 (Note: this contract was formerly UL1RR029884 from the National Center for


Research Resources) Arkansas Center for Clinical and Translational Research This program provides research infrastructure to increase the quality and quantity of clinical and translational research conducted in Arkansas. Role: Investigator/Informatics Expert (25%) Contract # HHSN275201300009C Topaloglu (PI) Health and Human Services Total amount: $2,030,459.00 National Children's Study (NCS) Information Management Systems (IMS) Hub CRIS has been tasked to be the IMS platform for the 10 National Children’s Study sites across the US. Role: Investigator (35%) Contract # N01-CO-12400 Topaloglu (PI) NIH/Nat. Cancer Institute Total amount: $134,554 caXhange adoption at UAMS Role: Programming Expert

Publications Senior/principal/corresponding author(s) = Underline. Self = bold Fellow = f Graduate Student = g Other = & Post-Doctoral Associate/Fellow = p Resident = r Impact Factor = IF Book

1. Bian J, Guo Y, He Z, Hu X. Social Web and Health Research: Benefits, Limitations, and Best Practices. 1st ed. Cham:Springer International Publishing; 2019. http://link.springer.com/10.1007/978-3-030-14714-3. Accessed July 5, 2019. doi: 10.1007/978-3-030-14714-3 Editorial

2. He Z, Tao C, Bian J, Zhang R, Huang J. Introduction: selected extended articles from the 2nd International Workshop on Semantics-Powered Data Analytics (SEPDA 2017). BMC Med Inform Decis Mak. 2018 Jul 23;18(Suppl 2):56. doi: 10.1186/s12911-018-0624-8. PMID: 30066636 PMCID: PMC6069756

3. He Z, Tao C, Bian J, Dumontier M, Hogan WR. Is it time to rethink institutional review boards for the era of big data? J Healthc Eng. 2017;2017:7983473. doi: 10.1155/2017/7983473. PMID: 29214005 PMCID: PMC5682067 Letters/Correspondence

4. Prosperi M, Bian J. Is it time to rethink institutional review boards for the era of big data? Nat Mach Intell. 2019. doi: 10.1038/s42256-019-0059-7 Journal Articles In Press

5. Wang Y, Zhao Y, Bian J, Zhang R. Detecting Associations between Dietary Supplement Intake and Sentiments within Mental Disorder Tweets. Health Informatics J. 2019. (In Press)

6. Fishe J, Bian J, Chen Z (p), Hu H, Min J, Modave F, Prosperi M. Prodromal comorbidity spectrum and ecological correlates of asthma syndrome in adults: A 10-year statewide big data analysis. J Asthma. 2019. (In Press) IF: 2.081 (2018)

7. He X (g), Zhang R (co-first), Rizvi R, Vasilakes J, Yang X, Guo Y, He Z,


Prosperi M, Huo J, Alpert J, Bian J. ALOHA: Developing an Interactive Graph-based Visualization for Dietary Supplement Knowledge Graph through User-Centered Design. BMC Med Inform Decis Mak. 2019. (In Press). 2019

8. Huo J, Chung TH, Kim B, Deshmukh AA, Salloum RG, Bian J. Provider-Patient Discussions about Smoking and the Impact of Lung Cancer Screening Guidelines: NHIS 2011-2015. J Gen Intern Med. 2019 Jun 21. doi: 10.1007/s11606-019-05111-6. [Epub ahead of print] PMID: 31228049

9. Macieira TGR (g), Chianca TCM, Smith MB, Yao Y, Bian J, Wilkie D, Dunn Lopez, K, Keenan G. Secondary use of standardized nursing care date for advancing nursing science and practice: A systematic review. J Am Med Inform Assoc. 2019 Jun 12. pii: ocz086. doi: 10.1093/jamia/ocz086. [Epub ahead of print]. PMID: 31188439

10. Ge S, Lu H, Li Q, Logan HL, Dodd VJ, Bian J, Shenkman EA, Guo Y. Classification Tree Analysis of Factors Associated with Oral Cancer Exam. Am J Health Behav. 2019 May 1;43(3):635-647. doi: 10.5993/AJHB.43.3.16. PMID: 31046892. IF: 1.27 (2018)

11. Chamberlain AM, Gong Y, Shaw KM, Bian J, Song WL, Linton MF, Fonseca V, Price-Haywood E, Guhl E, King JB, Shah RU, Puro J, Shenkman E, Pawloski PA, Margolis KL, Hernandez AF, Cooper-DeHoff RM. PCSK9 Inhibitor Use in the Real World: Data From the National Patient-Centered Research Network. J Am Heart Assoc. 2019 May 7;8(9):e011246. doi: 10.1161/JAHA.118.011246. PMID: 31020929. IF: 4.450 (2018)

12. Huo J, Hong YR, Bian J, Guo Y, Wilkie DJ, Mainous AG. Low Rates of Patient-Reported Physician-Patient Discussion about Lung Cancer Screening among Current Smokers: Data from Health Information National Trends Survey. Cancer Epidemiol Biomarkers Prev. 2019 Apr 25. doi: 10.1158/1055-9965.EPI-18-0629. PMID: 31023697. IF: 4.142 (2018)

13. Du J, Cunningham RM, Yang X, Li F, Jia Y, Boom JA, Myneni S, Bian J, Chen Y, Tao C. Leveraging deep learning to understand health beliefs about the Human Papillomavirus Vaccine from social media. npj Digit Med. 2019;2(1):1-27. doi: 10.1038/s41746-019-0102-4

14. Huo JH, Desai R, Hong YR, Turner K, Mainous III AG, Bian J. Use of Social Media in Health Communication: Findings from the Health Information National Trends Survey 2013 – 2017. 2019. Cancer Control. 2019 Jan-Dec;26(1):1073274819841442. doi: 10.1177/1073274819841442. PMID: 30995864. IF: 2.480 (2018)

15. Zhao Y (g), Guo Y (co-first), He X, Wu Y, Yang X, Prosperi M, Jin Y, Bian J. Assessing mental health signals among sexual and gender minorities using Twitter data. Health Informatics J. 2019 Apr 10:1460458219839621. doi: 10.1177/1460458219839621. [Epub ahead of print] PMID: 30969146. IF: 1.833 (2018)

16. Huo JH, Hong YR, Grewal R, Yadav S, Heller IW, Bian J, Wilkie DJ. Knowledge of Palliative Care among American Adults: 2018 Health Information National Trends Survey. J Pain Symptom Manage. 2019 Mar 25. pii: S0885-3924(19)30131-9. doi: 10.1016/j.jpainsymman.2019.03.014. [Epub ahead of print] PMID: 30922703. IF: 3.249 (2018)

17. Lee AM, Chavez S, Bian J, Thompson LA, Gurka MJ, Williamson VG, Modave F. Efficacy and Effectiveness of Mobile Health Technologies for Facilitating Physical Activity in Adolescents: Scoping Review. JMIR Mhealth Uhealth. 2019 Feb 12;7(2):e11847. PMID: 30747716 DOI: 10.2196/11847. IF: 4.541 (2018)

18. Guo Y, Bian J, Modave F, Li Q, George TJ, Prosperi M, Shenkman E. Assessing the effect of data integration on predictive ability of cancer survival models. Health Informatics J. 2019 Jan 23:1460458218824692. doi: 10.1177/1460458218824692. PMID: 30672356. IF: 1.833 (2018)

19. Yang X, Bian J, Gong Y, Hogan WR, Wu Y. MADEx: A System for Detecting Medications, Adverse Drug Events, and Their Relations from Clinical Notes. Drug Saf. 2019 Jan 2. doi: 10.1007/s40264-018-0761-0. [Epub ahead of print] PMID: 30600484 DOI: 10.1007/s40264-018-0761-0. IF: 3.585 (2018)

20. King F, Klonoff DC, Ahn D, Adi S, Berg EG, Bian J, Chen K, Drincic A, Heyl M,


Magee M, Mulvaney S, Pavlovic Y, Prahalad P, Ryan M, Sabharwal A, Shah S, Spanakis E, Thompson BM, Thompson M, Wang J. Diabetes Technology Society Report on the FDA Digital Health Software Precertification Program Meeting. J Diabetes Sci Technol. 2019 Jan;13(1):128-139. doi: 10.1177/1932296818810436. Epub 2018 Nov 5. PMID: 30394807 PMCID: PMC6313279 2018

21. Prosperi M, Min JS, Bian J, Modave F. Big data hurdles in precision medicine and precision public health. BMC Med Inform Decis Mak. 2018 Dec 29;18(1):139. doi: 10.1186/s12911-018-0719-2. PMID: 30594159 DOI: 10.1186/s12911-018-0719-2. IF: 2.134 (2018)

22. Chen Z, Min J, Bian J, Wang M, Zhou L, Prosperi M. Risk of health morbidity for the uninsured: 10-year evidence from a large hospital center in Boston, Massachusetts. Int J Qual Health Care. 2018 Aug 18. doi: 10.1093/intqhc/mzy175. [Epub ahead of print] PMID: 30137334 DOI: 10.1093/intqhc/mzy175. IF: 2.342 (2018)

23. Chen Z, Bird VY, Ruchi R, Segal MS, Bian J, Khan SR, Elie MC, Prosperi M. Development of a personalized diagnostic model for kidney stone disease tailored to acute care by integrating large clinical, demographics and laboratory data: the diagnostic acute care algorithm - kidney stones (DACA-KS). BMC Med Inform Decis Mak. 2018 Aug 17;18(1):72. doi: 10.1186/s12911-018-0652-4. PMID: 30119627 PMCID: PMC6098647. IF: 2.134 (2018)

24. Guo Y, Bian J, Li Q, Leavitt T, Rosenberg E, Buford TW, Smith MD, Vincent HK, Modave F. A 3-minute test of cardiorespiratory fitness for use in primary care clinics. PLoS One. 2018 Jul 30;13(7):e0201598. doi: 10.1371/journal.pone.0201598. eCollection 2018. PMID: 30059539 PMCID: PMC6066238 IF: 2.766.

25. Wang K, Meng W, Bian J, Li S, Yang S. Spatial context-aware user mention behavior modeling for mentionee recommendation. Neural Netw. 2018 Oct;106:152-167. doi: 10.1016/j.neunet.2018.07.007. Epub 2018 Jul 18. PMID: 30075352 IF: 7.197.

26. Zhang H (g), Guo Y, Hogan W, Li Q, George TJ, Shenkman EA, Modave, F, Bian J. An Ontology-guided Semantic Data Integration Framework to Support Integrative Data Analysis of Cancer Survival. BMC Med Inform Decis Mak. 2018 Jul 23;18(Suppl 2):41. doi: 10.1186/s12911-018-0636-4. PMID: 30066664 PMCID: PMC6069766 IF: 2.134

27. Lossio-Ventura JA (p), Hogan WR, Modave F, Guo Y, He Z, Yang X, Zhang H, Bian J. OC-2-KB: Integrating crowdsourcing into an obesity and cancer knowledge base curation system. BMC Med Inform Decis Mak. 2018 Jul 23;18(Suppl 2):55. doi: 10.1186/s12911-018-0635-5. PMID: 30066655 PMCID: PMC6069686. IF: 2.134

28. Chen Z, He Z, Liu X, Bian J. Evaluating semantic relations in neural word embeddings with biomedical and general domain knowledge bases. BMC Med Inform Decis Mak. 2018 Jul 23;18(Suppl 2):65. doi: 10.1186/s12911-018-0630-x. PMID: 30066651 PMCID: PMC6069806 IF: 2.134

29. Salloum RG, Lee JH, Porter M, Dallery J, McDaniel AM, Bian J, Thrasher JF. Evidence-based tobacco treatment utilization among dual users of cigarettes and E-cigarettes. PREV MED. 2018;114:193-199. doi: 10.1016/j.ypmed.2018.07.010. IF: 3.483

30. Lang L, Zhang L, Zhang P, Li Q, Bian J, Guo Y. Evaluating the reliability and validity of SF-8 with a large representative sample of urban Chinese. Health Qual Life Outcomes. 2018 Apr 3;16(1):55. doi: 10.1186/s12955-018-0880-4. PMID: 29615060 PMCID: PMC5883873. IF: 2.278

31. Lossio-Ventura JA (p), Bian J, Jonquet C, Roche M, Teisseire M. A novel framework for biomedical entity sense induction. J Biomed Inform. 2018 Jun 20. pii: S1532-0464(18)30113-8. doi: 10.1016/j.jbi.2018.06.007. PMID: 29935347. IF: 2.882

32. Zhao Y (g), Yoshigoe K, Xie M, Bian J, Xiong K. L-PowerGraph: a lightweight distributed graph-parallel communication mechanism. J SUPERCOMPUT. 2018. doi: 10.1007/s11227-018-2359-9. IF: 1.532


33. Wu B, Huang J, Zhang L, Kasukurthi MV, Huang F, Bian J, Fukuo K, Kazumi T. An integrative approach to investigate the association among high-sensitive C-reactive protein, body fat mass distribution, and other cardiometabolic risk factors in young healthy women. Methods. 2018 Apr 24. pii: S1046-2023(17)30489-9. doi: 10.1016/j.ymeth.2018.04.016. PMID: 29702223. IF: 3.998

34. Salloum R, George T, Silver N, Markham MJ, Hall J, Guo Y, Bian J, Shenkman E. Rural-Urban and Racial-Ethnic Differences in Awareness of Direct-to-Consumer Genetic Testing. BMC Public Health. BMC Public Health. 2018 Feb 23;18(1):277. PMID: 29471813 PMCID: PMC5824539. IF: 2.420

35. He Z, Bian J (co-first), Carretta H, Lee J, Hogan W, Shenkman E, Charness N. Comparative analysis of prevalence of multiple chronic conditions among older adults in Florida and the United States: Estimates from the OneFlorida Clinical Research Consortium Data Trust and National Inpatient Sample. J Med Internet Res. 2018 Apr 12;20(4):e137. doi: 10.2196/jmir.8961. PMID: 29650502 PMCID: PMC5920146. IF: 4.671

36. Chen H, Butler E, Guo Y, George T, Modave F, Gurka M, Bian J. Facilitation or Hindrance: Physicians' Perception on Best Practice Alerts (BPA) Usage in an Electronic Health Record System. Health Commun. 2018 Feb 27:1-7. doi: 10.1080/10410236.2018.1443263. PMID: 29485296. IF: 1.710.

37. Amith MF, He Z, Bian J, Lossio-Ventura JA (p), Tao C. Assessing the Practice of Ontology Evaluation for Biomedical Ontologies in BioPortal: Gaps and Opportunities. J Biomed Inform. 2018 Apr;80:1-13. doi: 10.1016/j.jbi.2018.02.010. PMID: 29462669 PMCID: PMC5882531. IF: 2.882 2017

38. Chen Y, Kho AN, Liebovitz D, Ivory C, Osmundson S, Bian J, Malin BA. Learning Bundled Care Opportunities from Electronic Medical Records. J Biomed Inform. 2017 Nov 22. pii: S1532-0464(17)30260-5. doi: 10.1016/j.jbi.2017.11.014. PMID: 29174994. IF: 2.882

39. Bian J, Zhao Y (g, co-first), Salloum RG, Guo Y, Wang M, Prosperi M, Zhang H, Du X, Ramirez-Diaz LJ, He Z, Sun Y. Using Social Media Data to Understand the Impact of Promotional Information on Laypeople’s Discussions: A Case Study of Lynch Syndrome. J Med Internet Res 2017;19(12):e414. DOI: 10.2196/jmir.9266. PMID: 29237586. IF: 4.671

40. Mansoor H (g), Elgendy IY, Segal R, Bavry AA, Bian J. Risk prediction model for in-hospital mortality in women with ST-elevation myocardial infarction: A machine learning approach. Heart Lung. 2017 Oct 6. pii: S0147-9563(17)30160-7. doi: 10.1016/j.hrtlng.2017.09.003. PMID: 28992993. IF: 1.730

41. Bian J, Guo Y (co-first), Xie M, Parish AE, Wardlaw I, Brown R, Modave F, Zheng D, Perry TT. Exploring the Association Between Self-Reported Asthma Impact and Fitbit-Derived Sleep Quality and Physical Activity Measures in Adolescents. JMIR Mhealth Uhealth 2017;5(7):e105 DOI: 10.2196/mhealth.7346. PMID: 28743679 PMCID: PMC5548986. IF: 4.541

42. He Z, Chen Z, Oh S, Hou J, Bian J. Enriching consumer health vocabulary through mining a social Q&A site: a similarity-based approach. J Biomed Inform. 2017 Mar 27. pii: S1532-0464(17)30065-5. doi: 10.1016/j.jbi.2017.03.016. [Epub ahead of print] PMID: 28359728. IF: 2.882

43. Culbertson A, Goel S, Madden MB, Safaeinili N, Jackson KL, Carton T, Waitman R, Liu M, Krishnamurthy A, Hall L, Cappella N, Visweswaran S, Becich MJ, Applegate R, Bernstam E, Rothman R, Matheny M, Lipori G, Bian J, Hogan W, Bell D, Martin A, Grannis S, Klann J, Sutphen R, O'Hara AB, Kho A. The Building Blocks of Interoperability. A Multisite Analysis of Patient Demographic Attributes Available for Matching. Appl Clin Inform. 2017 Apr 5;8(2):322-336. doi: 10.4338/ACI-2016-11-RA-0196. PMID: 28378025. IF: 1.138

44. Guo Y, Bian J, Leavitt T, Vincent HK, Vander Zalm L, Teurlings TL, Smith MD, Modave F. Assessing the Quality of Mobile Exercise Apps Based on the American College of Sports Medicine Guidelines: A Reliable and Valid Scoring Instrument. J Med Internet Res. 2017 Mar 7;19(3):e67. doi: 10.2196/jmir.6976.


PMID: 28270378 PMCID: PMC5360889. IF: 4.671 2016

45. Yuan J, Malin B, Modave F, Guo Y, Hogan WR, Shenkman E, Bian J. Towards a Privacy Preserving Cohort Discovery Framework for Clinical Research Networks. J Biomed Inform. 2017 Feb;66:42-51. doi: 10.1016/j.jbi.2016.12.008. PMID: 28007583 PMCID: PMC5316314. IF: 2.882 (2018 IMIA Yearbook of Medical Informatics Best Articles in “Between Access and Privacy: Challenges in Sharing Health Data”)

46. Perry T, Marshall A, Berlinski A, Rettiganti M, Brown R, Randle S, Luo C, Bian J. Smartphone-Based vs. Paper-Based Asthma Action Plans for Adolescents. Ann Allergy Asthma Immunol. 2017 Jan 19. pii: S1081-1206(16)31362-X. doi: 10.1016/j.anai.2016.11.028. PMID: 28111110. IF: 2.051

47. Modave F, Bian J, Rosenberg E, Mendoza T, Liang Z, Bhosale R, Maeztu C, Rodriguez C, Cardel MI. DiaFit: The Development of a Smart App for Patients with Type 2 Diabetes and Obesity. JMIR Diabetes 2016;1(2):e5. DOI: 10.2196/diabetes.6662.

48. Park MS, He Z, Chen Z, Oh S, Bian J. Consumers’ Use of UMLS Concepts on Social Media: Diabetes-Related Textual Data Analysis in Blog and Social Q&A Sites. JMIR Med Inform 2016;4(4):e41. doi: 10.2196/medinform.5748.

49. Zhao Y (g), Yoshigoe K, Bian J, Xie M, Xue Z, Feng Y. A distributed graph-parallel computing system with lightweight communication overhead. IEEE Transactions on Big Data. 2016;2(3):204-218. doi: 10.1109/TBDATA.2016.2532907

50. Cardel MI, Chavez S, Bian J, Peñaranda E, Miller DR, Huo T, Modave F. Accuracy of weight loss information in Spanish search engine results on the internet. Obesity (Silver Spring). 2016 Sep 21. doi: 10.1002/oby.21646. PMID: 27653438. IF: 4.042

51. Bian J, Yoshigoe K, Hicks A, Yuan J, He Z, Xie M, Guo Y, Prosperi M, Salloum R, Modave F. Mining Twitter to Assess the Public Perception of the "Internet of Things". PLoS One. 2016 Jul 8;11(7):e0158450. doi: 10.1371/journal.pone.0158450. PMID: 27391760. IF: 2.766

52. Milicchio F, Rose R, Bian J, Min J, Prosperi M. Visual programming for next-generation sequencing data analytics. BioData Mining. 2016;9:16. doi: 10.1186/s13040-016-0095-3. PMID: 27127540. IF: 1.857

53. Hanna J (g), Bian J, Hogan WR. An Accurate and Precise Representation of Drug Ingredients. J Biomed Semant. 2016 Apr 19;7:7. doi: 10.1186/s13326-016-0048-2. PMID: 27096073. IF: 1.600

54. Wei W, Hernandez I, Newman D, He J, Bian J. Twitter Analysis: Studying U.S. Weekly Trends in Work Stress and Emotion. Applied Psychology: An International Review. 2016;65:355-378. doi: 10.1111/apps.12065. IF: 2.490 2015

55. Modave F, Bian J, Leavitt T, Bronmwell J, Harris C, Vincent H. Low Quality of Free Coaching Apps with Respect to the American College of Sports Medicine Guidelines: A Review of Current Mobile Apps. JMIR Mhealth Uhealth. 2015 Jul 24;3(3):e77. doi: 10.2196/mhealth.4669. PMID: 26209109. IF: 4.541

56. Bush K, Cisler J, Bian J, Hazaroglu G, Hazaroglu O, Kilts C. Improving the Precision of fMRI BOLD Signal Deconvolution with Implications for Connectivity Analysis. Magn Reson Imaging. 2015 Dec;33(10):1314-1323. doi: 10.1016/j.mri.2015.07.007.PMID: 26226647. PMCID: PMC4658302 IF: 2.564

57. Bush K, Zhou S, Cisler J, Bian J, Hazaroglu O, Gillispie K, Yoshigo K, Kilts C. A Deconvolution-based Approach to Identifying Large-Scale Effective Connectivity. Magn Reson Imaging. 2015 Aug 4. pii: S0730-725X(15)00191-5. doi: 10.1016/j.mri.2015.07.015. PMID: 26248273. IF: 2.564

58. Bian J, Xie M, Hudson TJ, Eswaran H, Brochhausen M, Hanna J, Hogan WR. CollaborationViz: Interactive visual exploration of biomedical research collaboration networks, PLoS One. 2014 Nov 18;9(11):e111928. doi: 10.1371/journal.pone.0111928. eCollection 2014. PMID: 25405477. IF: 2.766

59. Zhao Y (g), Yoshigoe K, Xie M, Zhou S, Seker R, Bian J. Evaluation and Analysis of Distributed Big Data Processing Frameworks. Journal of Cyber


Security and Mobility - Special Issue on Big Data Theory and Practice. 2014;3(3):289-316. doi: 10.13052/jcsm2245-1439.333.

60. Bian J, Xie M, Hogan WR, Hutchins L, Topaloglu U, Lane C, Wells T. CLARA: an integrated clinical research administration system. J Am Med Inform Assoc. 2014;21(e2):e369-73. doi: 10.1136/amiajnl-2013-002616. PMID: 24778201. IF: 4.270

61. Bian J, Xie M, Topaloglu U, Hudson T, Eswaran H, Hogan WR. Social network analysis of biomedical research collaboration networks in a CTSA institution. J Biomed Inform. 2014 Dec;52:130-40. doi: 10.1016/j.jbi.2014.01.015. PMID: 24560679. IF: 2.882 2013

62. Bian J, Seker R. The Jigsaw secure distributed file system. Computers & Electrical Engineering. 2013;39(4):1142-1152. doi: 10.1016/j.compeleceng.2013.01.018. IF: 1.747 2012

63. Kanaskar N, Seker R, Bian J, Phoha VV. Dynamical System Theory for the Detection of Anomalous Behavior in Computer Programs. IEEE T SYST MAN CY C. 2012; 42(6):1579-1589. doi: 10.1109/TSMCC.2012.2208187. IF: 2.171

Conference Proceedings (peer-reviewed full papers) In computational related fields, such as biomedical informatics and computer science, premium conferences (e.g., AMIA and BIBM) are often more prestigious and selective than many journals.

In Press

64. Li Q (g, co-first), He Z (co-first), Guo Y (co-first), Zhang H, George TJ, Hogan WR, Charness N, Bian J. Assessing the Validity of a a prior Patient-Trial Generalizability Score using Real-world Data from a Large Clinical Data Research Network: A Colorectal Cancer Clinical Trial Case Study. AMIA Annu Symp Proc. 2019. (In Press)

65. Yang X, Gong Y, Waheed N, March K, Bian J, Hogan WR, Wu Y. Identifying Cancer Patients at Risk for Heart Failure Using Machine Learning Methods. AMIA Annu Symp Proc. 2019. (In Press)

66. He X, Zhang H, Yang X, Guo Y, Bian J. STAT: A Web-based Semantic Text Annotation Tool to Assist Building Mental Health Knowledge Base. Proceedings (IEEE ICHI). 2019. (In Press)

67. Rizvi R, Wang Y, Nguyen T, Vasilakes J, Bian J, He Z, Zhang R. Analyzing Social Media Data to Understand Consumers’ Information Needs on Dietary Supplements. MedInfo 2019. (In Press)

68. Payrovnaziri SN, Barrett LA, Bis D, Bian J. He Z. Enhancing Prediction Models for One-Year Mortality in Patients with Acute Myocardial Infarction and Post Myocardial Infarction Syndrome. MedInfo 2019. (In Press)

69. Modave F, Zhao Y, Krieger, He Z, Guo Y, Huo J, Prosperi M, Bian J. Understanding Perceptions and Attitudes in Breast Cancer Discussions on Twitter. MedInfo 2019. (In Press) 2019

70. Barrett LA, Payrovnaziri SN, Bian J, He Z. Building Computational Models to Predict One-Year Mortality in ICU Patients with Acute Myocardial Infarction and Post Myocardial Infarction Syndrome. AMIA Jt Summits Transl Sci Proc. 2019 May 6;2019:407-416. eCollection 2019. PMID: 31258994 2018

71. He X, Zhang R, Rizvi R, Vasilakes J, Yang X, Guo Y, He Z, Prosperi M, Bian J. Prototyping an Interactive Visualization of Dietary Supplement Knowledge Graph. Proceedings (IEEE Int Conf Bioinformatics Biomed). 2018. doi: 10.1109/BIBM.2018.8621340

72. Zhao Y (g), Guo Y, He X (g), Wu Y, Yang X, Bian J. Assessing Mental Health


Signals among Sexual and Gender Minorities using Twitter Data. Proceedings (IEEE ICHI). 2018;2018:51-52. DOI: 10.1109/ICHI-W.2018.00015.

73. Wang Y, Zhao Y (g), Bian J, Zhang R. Detecting Signals of Associations Between Dietary Supplement Use and Mental Disorders from Twitter. Proceedings (IEEE ICHI-W). 2018;2018:53-54 10.1109/ICHI-W.2018.00016.

74. Yang X, Bian J, Wu Y. Detecting Medications and Adverse Drug Events in Clinical Notes Using Recurrent Neural Networks. Proceedings (PMLR). 2018:90:1-6.

75. Du X (g), Bian J, Prosperi M. An Operatinal Deep Learning Pipeline for Classifying Life Events from Individual Tweets. Proceedings (Annu Symp on Information Management and Big Data). 2018;2018:54-66.

76. Zhang H (g), He Z, He X (g), Guo Y, Nelson DR, Modave F, Wu Y, Hogan WR, Bian J. Computable Eligibility Criteria through Ontology-driven Data Access: A Case Study of Hepatitis C Virus Trials. AMIA Annu Symp Proc. 2018 Dec 5;2018:1601-1610. eCollection 2018. PMID: 30815206 (Best Student Paper Finalists)

77. Wu Y, Xi Y, Bian J, Guo Y, Xu H, Hogan WR. Combine Factual Medical Knowledge and Distributed Word Representation to Improve Clinical Named Entity Recognition. AMIA Annu Symp Proc. 2018 Dec 5;2018:1110-1117. eCollection 2018. PMID: 30815153 2017

78. He Z, Gonzalez-Izquierdo A, Denaxas S, Dura A, Guo Y, Hogan WR, Shenkman E, Bian J. Comparing and Contrasting A Priori and A Posteriori Generalizability Assessment on Clinical Trials on Type 2 Diabetes Mellitus. AMIA Annual Symposium. AMIA Annu Symp Proc. 2018 Apr 16;2017:849-858. eCollection 2017. PMID: 29854151 PMCID: PMC5977671 (Distinguished Paper Award)

79. Lossio-Ventura JA (p), Hogan W, Modave F, Guo Y, He Z, Hicks A, Bian J. OC-2-KB: A software pipeline to build an evidence-based obesity and cancer knowledge base. Proceedings (IEEE Int Conf Bioinformatics Biomed). 2017 Nov;2017:1284-1287. doi: 10.1109/BIBM.2017.8217845. PMID: 29629236 PMCID: PMC5889048

80. Zhang H (g), Guo Y (co-first), Li Q, George TJ, Shenkman EA, Bian J. Data integration through ontology-based data access to support integrative data analysis: A case study of cancer survival. Proceedings (IEEE Int Conf Bioinformatics Biomed). 2017 Nov;2017:1300-1303. doi: 10.1109/BIBM.2017.8217849

81. Chen Z, He Z, Liu X, Bian J. An exploration of semantic relations in neural word embeddings using extrinsic knowledge. Proceedings (IEEE Int Conf Bioinformatics Biomed). 2017 Nov;2017:1246-1251. doi: 10.1109/BIBM.2017.8217836.

82. Wu B, Huang J, Kasukurthi M, Huang F, Bian J, Fukuo K, Suzuki K, Yoshino G, Kazumi T. Combine biological experiments, statistical analysis, and semantic search to discover association among high-sensitive C-reactive protein, body fat mass distribution, and other cardiometabolic risk factors in young healthy women. Proceedings (IEEE Int Conf Bioinformatics Biomed). 2017 Nov;2017:463-468. doi: 10.1109/BIBM.2017.8217692

83. He Z, Perl Y, Elhanan Ga, Chen Y, Geller J, Bian J. Auditing the Assignments of Top-Level Semantic Types in the UMLS Semantic Network to UMLS Concepts. Proceedings (IEEE Int Conf Bioinformatics Biomed). 2017 Nov;2017:1262-1269. doi: 10.1109/BIBM.2017.8217840

84. Lossio-Ventura JA (p), Hogan WR, Modave F, Hicks A, Hanna J, Guo Y, He Z, Bian J. Towards an obesity-cancer knowledge base: biomedical entity identification and relation detection. Proceedings (IEEE Int Conf Bioinformatics Biomed). 2016 Dec;2016:1081-1088. doi: 10.1109/BIBM.2016.7822672. Epub 2017 Jan 19. PMID: 28503356 PMCID: PMC5426361 2016

85. He Z, Che Z, Bian J. Analysis of Temporal Constraints in Qualitative Eligibility Criteria of Cancer Clinical Studies. Proceedings (IEEE Int Conf Bioinformatics


Biomed). 2016 Dec;2016:717-722. doi: 10.1109/BIBM.2016.7822607. PMID: 29263940 PMCID: PMC5733789

86. Li Y (g), Xie M, Bian J. SegAuth: A Segment-based Approach to Behavioral Biometric Authentication. IEEE Conf Commun Netw Secur. 2016 Oct;2016:1-9. doi: 10.1109/CNS.2016.7860464. Epub 2017 Feb 23. PMID: 28573214 PMCID: PMC5448984

87. He Z, Chen Z, George T, Lipori G, Bian J. Assessing the Population Representativeness of Colorectal Cancer Treatment Clinical Trials. Conf Proc IEEE Eng Med Biol Soc. 2016 Aug;2016:2970-2973. doi: 10.1109/EMBC.2016.7591353. PMID: 28268936 PMCID: PMC5727892

88. Zayas C (g), Maldonado-Molina MM, Zhe H, Yuan J, Hogan WR, Guo Y, Bian J. Examining Healthcare Utilization Patterns of Elderly and Middle-Aged Adults in the United States. Proc Int Fla AI Res Soc Conf. 2016 May;2016:361-366. PMID: 27430035.

89. He Z, Charness N, Bian J, Hogan W. Assessing the Comorbidity Gap between Clinical Studies and Prevalence in Elderly Patient Populations. IEEE EMBS Int Conf Biomed Health Inform. 2016 Feb;2016:136-139. Epub 2016 Apr 21. doi:10.1109/BHI.2016.7455853. PMID: 27738664.

90. Hicks A, Rutherford M, Fellbaum C, Bian J. An analysis of WordNet’s Coverage of Gender Identity Using Twitter and the National Transgender Discrimination Survey. Proc of the Global WordNet Conference (GWC 2016). 2016. 2015

91. Hicks A, Hogan WR, Rutherford M, Malin B, Xie M, Fellbaum C, Yin Z, Fabbri D, Hanna J, Bian J. Mining Twitter as a First Step toward Assessing the Adequacy of Gender Identification Terms on Intake Forms. AMIA Annu Symp Proc. 2015;2015:611-620. PMID: 26958196.

92. Li Y (g), Yang J, Xie M, Carlson D, Jang HG, Bian J. Comparison of PIN-and pattern-based behavioral biometric authentication on mobile devices. Proc of IEEE Military Communications Conference (MILCOM 2015). 2015;1317-1322. doi: 10.1109/MILCOM.2015.7357627.

93. Xie M, Li Y, Yoshigoe K, Bian J. CamAuth: Securing Web Authentication with Camera. Proc of 16th IEEE International Symposium on High Assurance Systems Engineering (HASE 2015). 2015;232-239. doi: 10.1109/HASE.2015.41. 2014

94. Li Y (g), Xie M, Bian J. USign – A Security Enhanced Electronic Consent Model Conf Proc IEEE Eng Med Biol Soc. 2014;2014:4487-90. doi: 10.1109/EMBC.2014.6944620. PMID: 25570988.

95. Zhao Y, Yoshigoe K, Xie M, Zhou S, Seker R, Bian J*. LightGraph : Lighten Communication in Distributed Graph-Parallel Processing. Proc of 2014 IEEE International Congress on Big Data (BigData Congress 2014). 2014;2014:717-724. doi: 10.1109/BigData.Congress.2014.106.

96. Hudson CL, Topaloglu U, Bian J, Hogan WR, Kieber-Emmons T. Automated Tools for Clinical Research Data Quality Control using NCI Common Data Elements. AMIA Jt Summits Transl Sci Proc. 2014 Apr 7;2014:60-9. PMID: 25717402. 2013

97. Xie M, Topaloglu U, Powell T, Peng C, Bian J. SIM: A Smartphone-based Identity Management Framework and Its Application to Arkansas Trauma Image Repository. Proc of 2013 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). 2013;2013:53-60. doi: 10.1109/BIBM.2013.6732600.

98. Bian J, Xie M, Topaloglu U, Hudson T, Hogan WR. Understanding Biomedical Research Collaborations through Social Network Analysis: A Case Study. Proc of 2013 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). 2013;2013:9-16. doi: 10.1109/BIBM.2013.6732728.

99. Xie M, Hao L, Yoshigoe K, Bian J. CamTalk: A Bidirectional Light Communications Framework for Secure Communications On Smartphones.


Security and Privacy in Communication Networks. 2013;127:35–52. doi: 10.1007/978-3-319-04283-1_3.

100. Bian J, Seker R, Xie M. A secure communication framework for large-scale unmanned aircraft systems. Proc of 2013 Integrated Communications, Navigation and Surveillance Conference (ICNS). 2013;2013:1-12. doi: 10.1109/ICNSurv.2013.6548542.

101. Bian J, Xie M, Topaloglu U, Cisler J. A Probabilistic Model of Functional Brain Connectivity Network for Discovering Novel Biomarkers. AMIA Jt Summits Transl Sci Proc. 2013 Mar 18;2013:21-5. eCollection 2013. PMCID: 24303289. 2012

102. Bian J, Topaloglu U, Yu F. Towards Large-scale Twitter Mining for Drug-related Adverse Events. Proc of 2012 ACM International Workshop on Smart Health and Wellbeing (SHB 2012). 2012;2012: 25-32. doi: 10.1145/2389707.2389713. PMID: 28967001 2011

103. Subramanian V, Seker R, Bian J, Kanaskar N. Collaborations, Mergers, Acquisitions, and Security Policy Conflict Analysis. Proc of the Seventh Annual Cyber Security and Information Intelligence Research Workshop (CSIIRW11). 2011;36. doi: 10.1145/2179298.2179337.

104. Bian J, Cisler J, Xie M, James A, Seker R, Kilts C. A Methodology for Empirical Analysis of Brain Connectivity through Graph Mining. Proc of 2011 IEEE International Conference on Systems, Man, and Cybernetics (SMC 2011). 2011;2011:2963-2969. doi: 10.1109/ICSMC.2011.6084151.

105. Kanaskar N, Seker R, Bian J. Dynamical System Approach to Insider Threat Detection. Proc of 2011 IEEE International Systems Conference. 2011;2011:232–238. doi: 10.1109/SYSCON.2011.5929116.

106. Bian J, Seker R, Topaloglu U, Bayrak, C. A Scalable Role-based Group Key Agreement and Role Identification Mechanism. Proc of 2011 IEEE International Systems Conference (SysCon 2011). 2011;2011:278-281. doi: 10.1109/SYSCON.2011.5929100. 2010

107. Bian J, Seker R, Topaloglu U. A Secure Distributed File System for Medical Image Archiving. Proc of 2010 IEEE International Conference on Privacy, Security, Risk, and, Trust (PASSAT 2010). 2010;2010:961-966. doi: 10.1109/SocialCom.2010.142. 2009

108. Bian J, Seker R, Ramaswamy S. JigDFS in Container Communities for International Cargo Security. Proc of 2009 IEEE International Conference on Systems, Man, and Cybernetics (SMC 2009). 2009;2009:3651-3656. doi: 10.1109/ICSMC.2009.5346865.

109. Bian J, Topaloglu U, Lane C. EIR: enterprise imaging repository, an alternative imaging archiving and communication system. Proc IEEE Eng Med Biol Soc. 2009;2009:2168-71. doi: 10.1109/IEMBS.2009.5332428. PMID: 19963537.

110. Bian J, Seker R, Ramaswamy S. JigDFS in Container Communities for International Cargo Security. (Extended Abstract). Proc of the 5th Annual Workshop on Cyber Security and Information Intelligence Challenges and Strategies (CSIIRW 09). 2009;19. doi: 10.1145/1558607.1558629.

111. Bian J, Seker R, Ramaswamy S, Yilmazer N. Container Communities: Anti-tampering Wireless Sensor Network for Global Cargo Security. Proc of 17th Mediterranean Conference on Control and Automation, MED09. 2009;2009:464-468. doi: 10.1109/MED.2009.5164585.

112. Bian J, Seker R. JigDFS: A Secure Distributed File System. Proc of IEEE Symposium Series on Computational Intelligence in Cyber Security (CICS 2009). 2009;2009:76-82. doi: 10.1109/CICYBS.2009.4925093.

113. Chiang C, Coskun B, Seker R, Topaloglu U, Demirer M, Samadi N, Tek S, Bian J, Zhou G, Wang X. Design of a Lattice-based Access Control Scheme. Proc of 2009 IEEE International Conference on Systems, Man, and Cybernetics (SMC


2009). 2009;2009:68-73. doi: 10.1109/ICSMC.2009.5346329. 2008

114. Bian J, Topaloglu U, Seker R, Bayrak C, Chiang C. A Role- based Secure Group Communication Framework. Proc of IEEE International Conference on System of Systems Engineering (SoSE 08). 2008;2008:1-6. doi: 10.1109/SYSOSE.2008.4724150.

115. Bian J, Seker R, Topaloglu U, Bayrak C. Off-the-Record Secure Chat Room. Proc of the Fourth International Conference on Web Information Systems and Technologies: Internet Technology (WEBIST 2008). 2008;1:54-61. 2007

116. Bian J, Seker R, Topaloglu U. Off-the-Record Instant Messaging for Group Conversation. Proc of IEEE International Conference on Information Reuse and Integration (IRI 2007). 2007;2007:79-84. doi: 10.1109/IRI.2007.4296601. Book Chapters 2019

117. Guo Y, Bian J. Social Media-Based Health Interventions: Where Are We Now? In: Bian J, Guo Y, He Z, Hu X (eds) Social Web and Health Research. Springer, Cham. 2019:15-30. doi: 10.1007/978-3-030-14714-3_2.

118. Zhang H, Wheldon C, Tao C, Dunn AG, Guo Y, Huo J, Bian J. How to Improve Public Health via Mining Social Media Platforms: A Case Study of Human Papillomaviruses (HPV). In: Bian J, Guo Y, He Z, Hu X (eds) Social Web and Health Research. Springer, Cham. 2019:207-231. doi: 10.1007/978-3-030-14714-3_11. 2013

119. Petty RH, Bian J, Seker R. Public Key Infrastructure. In: Information Resources Management A, ed. IT Policy and Ethics: Concepts, Methodologies, Tools, and Applications. Hershey, PA, USA: IGI Global; 2013:126-147. doi: 10.4018/978-1-4666-2919-6.ch007. 2011

120. Bian J, Seker R. JigDFS: A Secure Distributed File System for Medical Image Archiving. In: Suh SC, Gurupur VP, Tanik MM, eds. Biomedical Engineering: Springer New York; 2011:75-98. doi: 10.1007/978-1-4614-0116-2_6.

Abstracts and Presentations

Abstracts and posters 2019 28. Zhao Y, Huo J, Prosperi M, Guo Y, Li Y, Bian J. Exploring Lung Cancer Screening Discussions on Twitter. MedInfo 2019. August 26-30, 2019. Lyon, France. 27. Huo JH, Hong YR, Grewal R, Yadav S, Heller IW, Bian J, Wilkie DJ. Knowledge of Palliative Care among American Adults: 2018 Health Information National Trends Survey. International Society for Pharmacoeconomics and Outcomes Research (ISPOR) 24th Annual International Meeting. New Orleans, LA, USA, May 18-22, 2019

2018 26. Bian J, Sura A, Lipori G, Guo Y, Modave F, He Z, Shenkman E, Hogan WR. Implementing a Hash-based Privacy-Preserving Entity Resolution Tool in the OneFlorida Clinical Data Research Network. AMIA Annual Symposium. 2017. 25. He Z, Chen ZW, Mixon S, Bian J. A Visual Analysis Tool of Qualitative Eligibility Criteria of Clinical Studies. AMIA Annual Symposium. 2017.


24. Lossio-Ventura JA, Hogan WR, Modave F, Hicks A, Guo Y, He Z, Vasconcelos M, Bian J. Building an Obesity and Cancer Semantic Web Knowledge Base. AMIA Annual Symposium. 2017. 23. Hansi Z, Zhao YP, Wheldon C, Du XS, Brown T, Guo Y, Staras S, Du JC, Tao C, Bian J. A Twitter Study of the Relationship between the Geographic Variations of HPV Vaccination Rates and Online Information in the United States. AMIA Annual Symposium. 2017. 22. Modave F, Leavitt T, Kumar R, Bian J, Guo Y, Vincent HK. Relationship Between the Ruffier Test and Maximal Treadmill Testing in Healthy Adults. Am. Coll. Sports. Med. Annual Meeting. May 30-June 3, 2017. Denver, CO. 21. Modave F, Bian J, Cardel M, Mendoza T, Rosenberg E. DiaFit: An Integrated App for the Management of Diabetes and Obesity. North Am. Primary Care Research Group Annual Meeting. Montreal, QC, CA. Nov 17-21, 2017. 20. Huo T, George T, Guo Y, Prosperi M, Modave F, Bian J. Explore Care Pathways of Colorecatal Cancer Patients with Social Network Analysis. MedInfo 2017. 19. Mansoor H, Bian J. Risk prediction for in-hospital mortality in women with St-elevation myocardial infarction:A machine learning approach. Journal of the American College of Cardiology, Volume 69, Issue 11, Supplement, 21 March 2017, Page 171. 18. Wheldon C, Bian J, Moser R. Surveillance of HPV-related vaccination discourse on Twitter in the United States: A case study of Kansas and Rhode Island. 2016 International Conference on Social Media & Society. July 11-13, 2016. London, UK. Best Poster Award. 17. Zayas C, Maldonado-Molina M, Bian J. Using Machine Learning Methods to Examine Healthcare Utilization Patterns of Elderly and Middle-Aged Adults in the United States. Society for Prevention Research 24th Annual Meeting, San Francisco, CA, Tuesday, May 31, 2016 - Friday, June 3, 2016. 16. Delcher C, Bian J. Mining Twitter to Assess the Public Perception of Controlled Substances. Society for Prevention Research 24th Annual Meeting, San Francisco, CA, Tuesday, May 31, 2016 - Friday, June 3, 2016. 15. Perry TT, Rettiganti M, Bian J, Luo C, Schellhase DE, Brown RH, Randle SM, Berlinski A, Marshall SA. Utilization and Outcomes Associated with Mobile-Based Asthma Action Plans Compared to Paper Asthma Action Plans Among Adolescents. Poster presentation at the American Academy of Asthma Allergy and Immunology annual meeting. Los Angeles, CA, March 2016. 14. Hicks A, Hogan WR, He Z, Hanna J. Shenkman B, Yuan J, Bian J. Using Semantic Queries for Cohort Discovery Across Research Networks. Poster presented at the 2015 OHDSI Symposium. Washington, DC, October 2015. 13. Bian J, Xie M, Topaloglu U, Hudson T, Hogan WR. Interactive visualization for understanding and analyzing biomedical research collaboration networks - a pilot study. Poster presentation at the 2013 Workshop on Visual Analytics in Healthcare (in conjunction with the American Medical Informatics Association (AMIA) Annual Symposium). Washington, DC. Nov 16th, 2013. 12. Xie M, Bian J, Topaloglu U. Topic Modeling for Discovering Drug-related Adverse Events from Social Medial. Abstract at the 2013 AMIA Summit on Translational Bioinformatics, March 18 – 20, 2013, San Francisco, USA.


11. Recep A, Thomas S, Sinan K, Bian J, Hogan WR, Topaloglu U. Discovering Semantic Classes of Eligibility Criteria for Clinical Trials Using UMLS Semantic Types and Network Clustering. Abstract at the 2013 AMIA Summit on Translational Bioinformatics, March 18 – 20, 2013, San Francisco, USA. 10. Imus T, Hall-Barrow J, Benton T, Topaloglu U, Bian J, Martin P. Utilization and Training of a Statewide Trauma Image Repository. ATA 2012, American Telemedicine Association 17th Annual International Meeting & Exposition, April 29 – May 1, 2012, San Jose, California. 9. Topaloglu U, Bian J, Feng Z, Ermisoglu E, Perez J, Lane C, Hogan WR. Implementing an Enterprise Service Bus for the UAMS Comprehensive Research Informatics Suite, CTSA IKFC 2012. 8. Topaloglu U, Bian J, Hogan WR, Lane C, Wells T, Hutchins L. Informatics Solutions for Managing the Financial Aspects of Clinical Research at an Academic Health Center, AMIA CRI 2012. 7. Topaloglu U, Bian J, Hogan WR, Lane C, Wells T, Hutchins L. Budgeting issues and solutions for a clinical research in an academic health center. Poster presented at the face-to-face meeting of the Informatics Key Function Committee of the Clinical and Translational Science Award Consortium, Natcher Conference Center, NIH, Bethesda, MD, October 12, 2011. 6. Hogan WR, Topaloglu U, Lane C, Bian J, Kieber-Emmons T, Hutchins LF, Hobbs C. Adaptation of a caBIG-based Clinical Trials Management Suite to the National Children’s Study. Presented at the CTSA Consortium Informatics Key Function Committee Annual Face-to-face Meeting, Bethesda, MD, October 14, 2010. 5. Topaloglu U, Hogan WR, Lane C, Bian J, Kieber-Emmons T, Hutchins LF, Hobbs C. Evaluation of caBIG tools for the National Children's Study. caBIG Annual meeting 2010. 4. Topaloglu U, Saha R, Bian J, Bailey C, Lane C, Hogan WR, Hutchins LF, Kieber-Emmons T, Shaughnessy JJ. An Interoperable Framework to Link Biospecimen with Gene Array Data: a caArray and caTissue Integration Scenario. caBIG Annual meeting 2010. 3. Topaloglu U, Konduri SR, Lane C, Hogan WR, Bian J, Hutchins LF, Bailey C, Shaughnessy JJ, Konduri. caArray Standalone Client for auto uploading and importing array files. caBIG Annual meeting 2010. 2. Topaloglu U, Lane C, Hogan WR, Bian J, Jett T, Yayla I, Feng Z, Kieber-Emmons T, Hutchins LF. The caBIG(r) Suite implementation update at the UAMS. caBIG Annual meeting 2010. 1. Topaloglu U, Lane C, Hogan WR, Bian J, Yip V, Kieber-Emmons T, Hutchins LF. A System for Indexing Clinical Documents for Clinical and Translational Research. caBIG Annual meeting 2010. Presentations, Talks, and Panels

12. He Z, Wei D, Bian J, Liu J, Gong Y. Advancing Health Informatics Education and Health IT Workforce Development through Interdisciplinary Collaboration. MedInfo 2017. Accepted. 11. Bian J, Kho A, Goel S, Waitman R, Jiang X, Grannis S, Ong T. Implementing Record Linkage Solutions in the PCORnet Clinical Data Research Networks. AMIA CRI 2017. Panel. San Francisco, CA. March 29,


2017. 10. Bian J. Workshop on "Untangling the social web: Conceptual and methodical approaches to analyzing social web data." National Cancer Institute, Rockville, MD. April 13-14, 2016. 9. Bian J, Hanna J. Working with Big Data: Lessons from the OneFlorida Clinical Research Consortium. Department of Medicine Annual Retreat. April 30, 2016. 8. Bian J. A Probabilistic Model of Functional Brain Connectivity Network for Discovering Novel Biomarkers. Presented at 2013 Joint Summit on Translational Science, AMIA, 03/19/2013, San Francisco, USA 7. Bian J. Towards Large-scale Twitter Mining for Drug-related Adverse Events. Presented at the UALR EIT graduate seminar, 10/05/2012, Little Rock, AR 6. Bian J. Towards Large-scale Twitter Mining for Drug-related Adverse Events. Presented at the 2012 NSF Research Experience for Undergraduate, UCA, 6/28/2012, Conway, AR 5. Bian J. Large-scale Data Mining in Bioinformatics Research. Presented at the Cyberinfrastructure Day, 5/4/2012, Little Rock, AR

4. Bian J. Multi-disciplinary research: computer science, bioinformatics, and neuroinformatics. Presented at the HIT@UCA,6/20/2011, Conway, AR. 3. Bian J. JigDFS: The Jigsaw Secure Distributed File System and Its Applications. Presented at the UALR EIT graduate seminar, 3/18/2011, Little Rock, AR 2. Bian J. EIR: Enterprise Imaging Repository, An Alternative Imaging Archiving and Communication System. Paper presented at the 31st Annual International IEEE EMBS Conference, 09/03/2009, Minnesota, USA 1. Bian J. Off-the-Record Instant Messaging for Group Conversation. Paper presented at 2007 IEEE International Conference on Information Reuse and Integration, 08/13/2007, Las Vegas, USA