JOURNAL OF VIROLOGYVolume 32 Contents for December 1979 Number 3

Animal Viruses* Purification of the JS-3 Isolate of Herpesvirus ovis (Bovid Herpesvirus 4) and Some

Properties of Its DNA. E.-M. DE VILLIERS .............................. 705Immunochemical Characterization of Epstein-Barr Virus-Associated Early and

Late Antigens in n-Butyrate-Treated P3HR-1 Cells. BENGT KALLIN,* JANOSLuKA, AND GEORGE KLEIN ............................................. 710

Regulation of the Primary Expression of the Early Adenovirus TranscriptionUnits. JOSEPH R. NEVINS,,* HAROLD S. GINSBERG, J.-M. BLANCHARD, MI-CHAEL C. WILSON, AND JAMES E. DARNELL, JR........................... 727

Alterations in Glycosphingolipid Patterns in a Line of African Green MonkeyKidney Cells Infected with Herpesvirus. EDWARD W. SCHRODER AND JOSEPHM. MERRICK* ... .............. ... ... 734

_ Herpes Simplex Virus Glycoproteins: Participation of Individual Herpes SimplexVirus Type 1 Glycoprotein Antigens in Immunocytolysis and Their Correlationwith Previously Identified Glycopolypeptides. B. NORRILD,* S. L. SHORE,AND A. J. NAHMIAS .................................................... 741

gag-Related Polypeptides Encoded by Replication-Defective Avian Oncoviruses.CARL W. RETTENMIER,* STEVEN M. ANDERSON, MARK W. RIEMEN, ANDHIDESABURO HANAFUSA ............................... 749

Analysis of Cellular Integration Sites in Avian Sarcoma Virus-Infected DuckEmbryo Cells. TONA M. GILMER AND J. THOMAS PARSONS* .... .......... 762

Protease Required for Processing Picornaviral Coat Protein Resides in the ViralReplicase Gene. ANN C. PALMENBERG,* MARK A. PALLANSCH, AND ROLANDR. RUECKERT ......................................................... 770

-Membrane Proteins Specified by Herpes Simplex Viruses. V. Identification of anFc-Binding Glycoprotein. ROBERT B. BAUCKE AND PATRICIA G. SPEAR* ... 779

Stabilization of "A" Particles of Coxsackievirus B3 by a HeLa Cell Plasma Mem-brane Extract. MARY L. MCGEADY AND RICHARD L. CROWELL* .... ...... 790

Polypeptides of Hepatitis B Virus Surface Antigen Produced by a Hepatoma CellLine. PATRICIA L. MARION, FELIX H. SALAZAR, JENNIFER J. ALEXANDER,AND WILLIAM S. ROBINSON* .......... ................. 796

5'-Terminal Nucleotide Sequences of the Rauscher Leukemia Virus and GibbonApe Leukemia Virus Genomes Exhibit a High Degree of Correspondence.GERALD G. LOVINGER AND GERALD SCHOCHETMAN* ....... 803

Analysis of the DNAs from Seven Varicella-Zoster Virus Isolates. JAMES C.RICHARDS, RICHARD W. HYMAN,* AND FRED RAPP ....................... 812

Persistence of Infectious Friend Virus in Spleens of Mice After SpontaneousRecovery from Virus-Induced Erythroleukemia. BRUCE CHESEBRO,* MAR-SHALL BLOOM, KATHY WEHRLY, AND JANE NISHIO ...... ................. 832

Inactivation of Influenza and Vesicular Stomatitis Virion RNA Polymerase Activi-ties by Photoreaction with 4'-Substituted Psoralens. KUNIo NAKASHIMA,PRANAB K. CHANDA, VICTOR DEUTSCH, AMIYA K. BANERJEE, AND AARONJ. SHATKIN * ...........................................................838

Establishment of a C3Hf Mammary Tumor Cell Line Expressing EndogenousMouse Mammary Tumor Virus: Antigenic and Genetic Relationships of ThisVirus with Highly Oncogenic Mouse Mammary Tumor Viruses. LARRY 0.ARTHUR,* GERALD G. LOVINGER, AND GERALD SCHOCHETMAN ..... ........ 852

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Continued from precedingpage

Restriction Endonuclease Mapping of Unintegrated Proviral DNA of Snyder-Thei-len Feline Sarcoma Virus: Localization of Sarcoma-Specific Sequences.CHARLES J. SHERR,* Louis A. FEDELE, LUDVIK DONNER, AND LUBOMIR P.TUREK ...... .................... ... 860

UV Inactivation of the Biological Activity of Defective Interfering Particles Gen-erated by Vesicular Stomatitis Virus. PAULINE H. S. BAY AND M. E. REICH-MANN ........................................... 876w

Correlation Between Epstein-Barr Virus Membrane Antigen and Three Large CellSurface Glycoproteins. BRUCE C. STRNAD,* RUSSELL H. NEUBAUER, HARVEYRABIN, AND RICHARD A. MAZUR.885

Cap and Intemal Nucleotides of Reovirus mRNA Primers Are Incorporated intoInfluenza ViralComplementaryRNA During Transcription In Vitro. MICHELEBOULOY, MAUREEN A. MORGAN, AARON J. SHATKIN, AND ROBERT M. KRUG* 895

Conserved Region of Mammalian Retrovirus RNA. R. KOMINAMI AND M. HA-TANAKA* .................... .... 925

Viable Deletion Mutant of Human Papovavirus BK That Induces Insulinomas inHamsters. SUMIE WATANABE,* KUNITO YOSHIIKE, AKEMI NOZAWA, YASU-HITO YUASA, AND SEIJIRO UCHIDA .................... .. ;............. 934

Transformation of Primary Rat Kidney Cells by DNA Fragments of WeaklyOncogenic Adenoviruses. REIN DIJKEMA,* BEN M. M. DEKKER, MACHTELDJ. M. VAN DER FELTZ, AND ALEX J. VAN DER EB....... 943

Genome Organization of Retroviruses. VI. Heteroduplex Analysis of Ecotropic andXenotropic Sequences of Moloney Mink Cell Focus-Inducing Viral RNA Ob-tained from Either a Cloned Isolate or a Thymoma Cell Line. ROBERT A.BOSSELMAN, LEO J. L. D. VAN GRIENSVEN, MARGUERITE VOGT, AND INDERM.VERMA*.............. 968

Simian Virus 40 Small t Antigen Is Not Required for the Maintenance of Transfor-mation but May Act as a Promoter (Cocarcinogen) During Establishment ofTransformation in Resting Rat Cells. ROLAND SEIF* AND ROBERT G. MARTIN 979

Retransformation of a Simian Virus 40 Cell Line, Which Is Resistant to Viral andDNA Infections, by Microinjection of Viral DNA. A. GRAESSMANN, M.GRAESSMANN, W. C. ToPP,* AND M. BOTCHAN... 989

In Vitro Association of Empty Adenovirus Capsids with Double-Stranded DNA.CLARK TIBBETTS* AND CHOU-ZEN GIAM... .. . 995

Isolation of Influenza C Virus Recombinants. VINCENT R. RACANIELLO ANDPETER PALESE* .. .......... .. 1006

Comparative Study of Different Isolates of Murine Sarcoma Virus. DANIEL J.DONOGHUE,* PHILLIP A. SHARP, AND ROBERT A. WEINBERG. 1015

Heteroduplex Analysis of the RNA of Clone 3 Moloney Murine SarcomaVirus. YUEH-HSIU CHIEN, INDER M. VERMA, P. H. DUESBERG, AND NORMANDAVIDSON* .. .............. 1028

Herpes Simplex Virus DNA Synthesis in a Partially Purified Soluble Extract fromInfected Cells. PIER F. PIGNATTI,* ENZO CASSAI, AND UMBERTO BERTAZZONI 1033

Inhibition of Influenza C Virus Replication by Actinomycin D, a-Amanitin, and UVIradiation. THOMAS PETRI, HERBERT MEIER-EWERT, AND RICHARD W.COMPANS* ......... .................. 1037 --

The Nonstructural Component of the Abelson Murine Leukemia Virus PolyproteinP120 Is Encoded by Newly Acquired Genetic Sequences. WIM J. M. VAN DE

VEN, FRED H. REYNOLDS, JR., ROBERT P. NALEWAIK, AND JOHN R. STEPHEN-SON ........................ .. .. 1041

Peptide Map Comparison of the Proteins of Infectious Bursal DiseaseVirus. PETER DOBOS ................................................. 1046

Continued on followingpage

Continued firomprecedingpage

Characterization of Intracellular Precursor Polyproteins of Moloney Murine Leu-kemia Virus. V. L. NG, T. G. WOOD, D. D. LYONS, AND R. B. ARLINGHAUS* 1051

Bacterial VirusesComposition and Molecular Organization of Lipids and Proteins in the Envelope of

Mycoplasmavrus MVL2. NOA GREENBERG AND SHLOMO ROTTEM* ..... 717Host Transcription in Bacteriophage P22-Infected Salmonella typhimurium.

JAMES M. PIPAS AND ROBERT H. REEVES* ............................... 822In Vivo Methylation of Bacteriophage oX174 DNA. STANLEY HATTMAN,* CHRIS

GRIBBIN, AND CLYDE A. HUTCHISON III .. ............ .. 845regA Protein of Bacteriophage T4D: Identification, Schedule of Synthesis, and

Autogenous Regulation. THOMAS S. CARDILLO, EDWARD F. LANDRY, ANDJOHN S. WIBERG* ..................................................... 905

Inhibition of Initiation of Bacteriophage T4 DNA Replication by Perturbation ofEscherichia coli Host Membrane Composition. WAI M. HUANG .... ...... 917

Characterization of a Bacteriophage Related to R-Type Pyocins. MAKOTO KA-GEYAMA,* ToMOYUKI SHINOMIYA, YOSHImI AIHARA, AND MIEKo KOBAYASHI 951

Bactericidal Activity of the Tail of Pseudomonas aeruginosa BacteriophagePS17. ToMOYUKI SHINOMIYA* AND SAWAKO SHIGA ...................... 958

ErratumInhibition of Herpes Simplex Virus-Induced DNA Polymerase Activity and Viral

DNA Replication by 9-(2-Hydroxyethoxymethyl)guanine and Its Thiphos-phate. PHILLIP A. FURMAN, MARTY H. ST. CLAIR, JAMES A. FYFE, JANET L.RIDEOUT, PAUL M. KELLER, AND GERTRUDE B. ELION ........ 1057

* Asterisk refers to person to whom inquiries regarding the paper should be addressed.

Volume 32 Contents for October 1979 Number 1

Animal VirusesIdentification of Transcribed Regions of Epstein-Barr Virus DNA in Burkitt Lym-

phoma-Derived CeUs. LARS RYMO ..................................... 8Functional Defects of RNA-Negative Temperature-Sensitive Mutants of Sindbis

and Semliki Forest Viruses. SIRKKA KERANEN* AND LEEVI KAARIAINEN.. 19Physical Map of Biologically Active Harvey Sarcoma Virus Unintegrated Linear

DNA. MITCHELL P. GOLDFARB AND ROBERT A. WEINBERG*.30Immune Response to the src Gene Product in Mice Bearing Tumors Induced by

Injection of Avian Sarcoma Virus-Transformed Mouse Cells. SARAH J. PAR-SONS, SYLVIA C. RILEY, EDWARD E. MULLEN, EMILY J. BROCK, DAVID C.BENJAMIN, W. MICHAEL KUEHL, AND J. THOMAS PARSONS* .............. . 40

Expression of Simian Virus 40 Gene A Affects Tubulin Stability. GERHARDWICHE,* REINHARD FURTNER, NANCY STEINHAUS, AND R. DAVID COLE 47

Methylation of Nuclear Simian Virus 40 RNAs. YOSEF ALONI,* RAVI DHAR, ANDGEORGE KHOURY ...................................................... 52

Adenovirus Early Function Required for Protection of Viral and CellularDNA. JEAN-CLAUDE D'HALLUIN,* CHANTAL ALLART, CHANTAL COUSIN,PIERRE A. BOULANGER, AND GUY R. MARTIN ......... ................... 61

Inhibition of Herpes Simplex Virus-Induced DNA Polymerase Activity and ViralDNA Replication by 9-(2-Hydroxyethoxymethyl)guanine and Its Triphos-phate. PHILLIP A. FURMAN,* MARTY H. ST. CLAIR, JAMES A. FYFE, JANET L.RIDEOUT, PAUL M. KELLER, AND GERTRUDE B. ELION .................... 72

Pheasant Virus DNA Polymerase Is Related to Avian Leukosis Virus DNA Polym-erase at the Active Site. GEORG BAUER AND HOWARD M. TEMIN* ......... 78

Adenovirus DNA Template for Late Transcription Is Not a Replicative Interme-diate. 0. BRISON, C. KEDINGER, AND P. CHAMBON* .. .... 91

Tryptic Peptide Analysis of Avian Oncovirus gag and pol Gene Products. CARLW. RETTENMIER,* ROGER E. KARESS, STEVEN M. ANDERSON, AND HIDESA-BURO HANAFUSA ...................................................... 102

Characterization of the Proteins of Intracisternal Type A and Extracelular Oncor-navirus-Like Particles Produced by MOPC-460 Myeloma Cells. DONALD L.ROBERTSON, PERIN S. JHABVALA, THERESE GODEFROY-COLBURN, AND ROB-ERT E. THACH* ...................... .... 114

Characterization of Infectious Oncornaviruses from MOPC-460 Plasmacytomas:Their Relation to A-Type Particles. TRIPRAYAR V. RAMABHADRAN, JANETW. HARTLEY, WALLACE P. ROWE, THERESE GODEFROY-COLBURN, PERIN S.JHABVALA, AND ROBERT E. THACH* ..................................... 123

Mice with Spontaneous Mammary Tumors Develop Type-Specific Neutralizingand Cytotoxic Antibodies Against the Mouse Mammary Tumor Virus EnvelopeProtein gp52. GERALD SCHOCHETMAN,* LARRY 0. ARTHUR, CEDRIC W. LONG,AND RICHARD J. MASSEY .......................... 131

Mutant of Herpes Simplex Virus Type 2 with Temperature-Sensitive LesionsAffecting Virion Thermostability and DNase Activity: Identification of theLethal Mutation and Physical Mapping of the nuc- Lesion. H. Moss, P.CHARTRAND, M. C. TIMBURY, AND J. HAY* ...... ........................ 140

Cellular Proteins Associated with Simian Virus 40 Early Gene Products in NewlyInfected Cells. YU-CHUNG YANG, PATRICK HEARING, AND KATHLEEN RUN-DELL* ... ... ................. 147

Isolation of a Soluble and Template-Dependent Poliovirus RNA Polymerase ThatCopies Virion RNA In Vitro. JAMES B. FLANEGAN * AND TERRY A. VANDYKE ............................................ 155

Asterisk refers to person to whom inquiries regarding the paper should be addressed.

CONTENTS

Terminal Sequences of Vesicular Stomatitis Virus RNA Are Both Complementaryand Conserved. JACK D. KEENE, MANFRED SCHUBERT, AND ROBERT A.LAZZARINI * ........................................................... 167

Cell Fusion for Genetic Analysis of Two Nonconditional Rous Sarcoma VirusReplication Mutants. KATHELYN S. STEIMER* AND DAVID BOErrIGER .... 175

Characterization of 40,000- and 25,000-Dalton Intermediate Precursors to RauscherMurine Leukemia Virus gag Gene Products. R. B. NASO, W. L. KARSHIN, Y.H. Wu, AND R. B. ARLINGHAUS* ........................................ 187

Conserved Polynucleotide Sequences Among the Genomes of Papillomavi-ruses. MING-FAN LAW,* WAYNE D. LANCASTER, AND PETER M. HOWLEY 199

Oligoribonucleotide Map and Protein of CMII: Detection of Conserved and Non-conserved Genetic Elements in Avian Acute Leukemia Viruses CMII, MC29,and MH2. KLAUS BISTER, HANS-CHRISTOPH LOLIGER, AND PETER H. DUES-BERG*................................... .. ........ 208

Comparative Analysis of GS and BK Virus Genomes. MARY M. PATER,* ALANPATER, AND GIAMPIERO DI MAYORCA .................................... 220

Hepatitis B Viral DNA Molecules Have Cohesive Ends. FRED SATTLER ANDWILLIAM S. ROBINSON* ................................................ 226

Apparent Posttranscriptional Block to Anaerobic Induction of Endogenous Leuke-mia Virus. PATRICIA A. WHITAKER-DOWLING, KEITH R. MAROTTI, ANDGARTH R. ANDERSON* ........................... 234

Structure and Function of Adenovirus Type 12 Defective Virions. I. MAK, H.EZOE, AND S.MAK*................... ........... ........ ..... 240

Impaired Maturation of Mouse Mammary Tumor Virus Precursor Polypeptides inLymphoid Leukemia Cells, Producing Intracytoplasmic A Particles and NoExtracellular B-Type Virions. ROELAND NUSSE,* LEX VAN DER PLOEG, LUUKVAN DUIJN, ROB MICHALIDES, AND Jo HILGERS .......................... 251

Human Cytomegalovirus-Induced Immediate Early Antigens: Analysis in SodiumDodecyl Sulfate-Polyacrylamide Gel Electrophoresis After Immunoprecipita-tion. SUSAN MICHELSON, FLORIAN HORODNICEANU,* MICHEL KRESS, ANDMARYSE TARDY-PANIT ................................................. 259

Incomplete Genomes of the Parvovirus Minute Virus of Mice: Selective Conserva-tion of Genome Termini, Including the Origin for DNA Replication. EMANUELA. FAUST AND DAVID C. WARD ........................................ 276

Electron Microscopic Mapping of RNA Transcribed from the Late Region ofPolyoma Virus DNA. HAIM MANOR, MADELINE WU, NAVA BARAN, ANDNORMAN DAVIDSON* ................................................... 293

Assembly of Vesicular Stomatitis Virus Nucleocapsids In Vivo: a Kinetic Analy-SiS. CHUNG-HSIUNG HSU, DAVID W. KINGSBURY, * AND KURUGANTI G.MURTI ......................... 304

Serological Relationship of Woodchuck Hepatitis Virus to Human Hepatitis BVirus. BARBARA G. WERNER,* JO M. SMOLEC, ROBERT SNYDER, AND JESSESUMMERS ............................................................. 314

Further Morphological Characterization and Structural Proteins of Infectious Bur-sal Disease Virus. K. HIRAI,* N. KATO, A. FUJIURA, AND S. SHIMAKURA ... 323

Infective Substructures of Measles Virus from Acutely and Persistently InfectedCells. SHMUEL RoZENBLATT,* TAMAR KOCH, ORIT PINHASI, AND SUSANBRATOSIN ............................................................. 329

Secondary Structures in Polyoma DNA. MADELINE Wu, HAIM MANOR, ANDNORMAN DAVIDSON * ................................................... 334

Mappings of Adenovirus Type 7 Cytoplasmic RNA Species Synthesized Early inLytically Infected Cells and Synthesized in Transformed Cells. KoUICHIYOSHIDA, KENJI SEKIKAWA, AND KEI FUJINAGA*.............. 339

CONTENTS

Detection of Polymorphism in BALB/c Leukemia Viruses with MouseAntisera. JOSEPH P. BROWN, MAURO BOIOCCHI, AND ROBERT C. NOWINSKI* 345

Polymorphism of B-Tropic Leukemia Viruses from BALB/c Mice: Association of ap30 Antigen with N- Versus B-Tropism. ELLEN TRESS, PAUL V. O'DONNELL,NANCY FAMULARI, RONALD W. ELLIS, AND ERWIN FLEISSNER*.350

Bacterial VirusesRegulation of Late Functions in Salmonella Bacteriophages P22 and L Studied by

Assaying Endolysin Synthesis. WERNER BODE .......................... 1Is the Injection of DNA Enough to Cause Bacteriophage P22-Induced Changes in

the Cellular Transport Process of Salmonella typhimurium? P. N. BANDYO-PADHYAY, B. DAS GUPTA, ARATI JOSHI, AND MAHARANI CHAKRAVORTY* 98

Heat-Sensitive Lambda Repressors Retain Partial Activity During BacteriophageInduction. MARGARET LIEB ........................................... 162

Structural and Biological Properties of Mycoplasmavirus MVL3: an Unusual Virus-Procaryote Interaction. KLAUS HABERER, GUNTHER KLOTZ, JACK MANI-LOFF,* AND ALBRECHT K. KLEINSCHMIDT .. ..... ..... 268

Volume 32 Contents for November 1979 Number2Animal Viruses

Abnormal Properties of an Immediate Early Polypeptide in Cells Infected with theHerpes Simplex Virus Type 1 Mutant tsK. C. M. PRESTON ............... 357

Two Avian Sarcoma Virus Mutants with Defects in the DNA Polymerase-RNaseH Complex. KARIN MOELLING* AND ROBERT R. FRIIS ................... 370

Transforming DNA Sequences in Rat Cells Transformed by DNA Fragments ofHighly Oncogenic Human Adenovirus Type 12. YUKIHARU SAWADA, SET-SUKO OJIMA, HIROTO SHIMOJO, KAZUKO SHIROKI, AND KEI FUJINAGA*. 379

Replication of Polyoma DNA in Isolated Nuclei: Analysis of Replication ForkMovement. GORAN MAGNUSSON* AND MAJ-GRETH NILSSON .... ......... 386

Synthesis and Processing of Adenoviral RNA in Isolated Nuclei. V. W. YANG ANDS. J. FLINT* ........................................................... 394

Nucleotide Sequences from the 3' Ends of Vesicular Stomatitis Virus mRNA's asDetermined from Cloned DNA. JOHN K. RoSE* AND LINDA IVERSON. 404

Inhibition of Rous Sarcoma Virus Replication by 2-Deoxyglucose and Tunicamycin:Identification of an Unglycosylated env Gene Product. ROBERT STOHRERAND ERIC HUNTER* .................................................... 412

Persistent Vesicular Stomatitis Virus Infection Mediates Base Substitutions inViral RNA Termini. BERT L. SEMLER AND JOHN J. HOLLAND* ........... 420

BamI, KpnI, and SalI Restriction Enzyme Maps of the DNAs of Herpes SimplexVirus Strains Justin and F: Occurrence of Heterogeneities in Defined Regionsof the Viral DNA. HILLA LOCKER AND NIZA FRENKEL* ..... ............. 429

Macromolecular Synthesis in Cells Infected by Frog Virus 3. XII. Viral RegulatoryProteins in Transcriptional and Post-Transcriptional Controls. RAKESHGOORHA, DAWN B. WILLIS, AND ALLAN GRANOFF*.. 442

DNase Induced After Infection of KB Cells by Herpes Simplex Virus Type 1 orType 2. II. Characterization of an Associated Endonuclease Activity. PETERJ. HOFFMANN AND YUNG-CHI CHENG* ................................... 449

Polypeptides of the Epstein-Barr Virus Membrane Antigen Complex. DAVID A.THORLEY-LAWSON* AND CLARK M. EDSON.. 458

CONTENTS

Infectivity of the DNA from Four Isolates of JC Virus. RICHARD J. FRISQUE,*JONATHAN D. MARTIN, BILLIE L. PADGETT, AND DUARD L. WALKER ....... 476

Organization of Mouse Mammary Tumor Virus-Specific DNA Endogenous toBALB/c Mice. J. CRAIG COHEN,* JOHN E. MAJORS, AND HAROLD E. VARMUS 483

Polyprotein Precursors to Mouse Mammary Tumor Virus Proteins. S. J. ANDER-SON, R. B. NASO,* J. DAVIS, AND J. M. BOWEN........ 507

Isolation and Characterization of Polyoma Virus Genomes with Deletions Betweenthe Origin of Viral DNA Replication and the Site of Tnitiation of Translationin the Early Region. ROBERT D. WELLS, MARY A. HUTCHINSON, AND WALTERECKHART* ...................... ......... .... 517

Construction and Analysis of Viable Deletion Mutants of Polyoma Virus. GORANMAGNUSSON AND PAUL BERG* ........................................... 523

Deletion Mutants of Polyoma Virus Defining a Nonessential Region Between theOrigin of Replication and the Initiation Codon for Early Proteins. MARY M.BENDIG AND WILLIAM R. FOLK* ............................. 530

Evidence for the Identity of Shared 5'-Termninal Sequences Between Genome RNAand Subgenonic mRNA's of B77 Avian Sarcoma Virus. C. MARTIN STOLTZ-FUS* AND LEE K. KUHNERT ............................................ 536

Analysis of the src Gene of Sarcoma Viruses Generated by Recombination BetweenTransformation-Defective Mutants and Quail Cellular Sequences. L.-H.WANG,* C. MoscovIcI, R. E. KARESS, AND H. HANAFUSA ............... ... 546

Hormonal Regulation of Murine Mammary Tumor Virus RNA Expression DuringMammary Tumorigenesis in BALB/c Mice. ROBERT J. PAULEY, DANIELMEDINA, AND SUSAN H. SOCHER* ................................. 557

Deletion Mutant of the Bratislava-77 Strain of Rous Sarcoma Virus Containing aFusion of the Group-Specific Antigen and Envelope Genes. PETER M.DIERKS, PETER E. HIGHFIELD, AND J. THOMAS PARSONS* ................. 567

Biophysical and Biochemical Characterization of Five Animal Viruses with Biseg-mented Double-Stranded RNA Genomes. PETER DOBOS,* BARRY J. HILL,Ross HALLETT, DAVID T. C. KELLS, HERMANN BECHT, AND DANIELLE TEN-INGES ............. 593

Mechanism of Vaccinia Virus Release and Its Specific Inhibition by NI-Isonicoti-noyl-N2-3-Methyl-4-Chlorobenzoylhydrazine. LENDON G. PAYNE* AND KRIS-TER KRISTENSON .............................................. 614

Physical Mapping of a Large-Plaque Mutation of Adenovirus Type 2. G. CHIN-NADURAI,* SHANBAGAM CHINNADURAI, AND JOHN BRUSCA.623

In Vitro Reassembly of Infectious Polyoma Virions. J. N. BRADY, J. D. KENDALL,AND R. A. CONSIGLI*.640

Intracellular Localization of Viral Polypeptides During Simian Virus 40Infection. HARUMI KASAMATSU* AND ANGELA NEHORAYAN... 648

Density-Dependent Inhibition of Both Growth and T-Antigen Expression in Re-vertants Isolated from Simian Virus 40-Transformed Mouse SVT2 Cells.ELIZABETH G. GURNEY* AND THEODORE GURNEY, JR............661

Phosphoproteins of Murine Hepatitis Viruses. STEPHEN A. STOHLMAN* ANDMICHAEL M. C. LAI .................................................... 672

Production of Monoclonal Antibodies Against Nucleocapsid Proteins of HerpesSimplex Virus Types 1 and 2. MARTIN ZWEIG,* CONRAD J. HEILMAN, JR.,HARVEY RABIN, RALPH F. HOPKINS III, RUSSELL H. NEUBAUER, AND BERGEHAMPAR ...... .................................. 676

Differential Adsorption of Polyoma Virions and Capsids to Mouse Kidney Cellsand Guinea Pig Erythrocytes. JOSEPH B. BOLEN AND RICHARD A. CONSIGLI* 679

Physical Maps of Bovine Papillomavirus Type 1 and Type 2 Genomes. WAYNE D.LANCASTER ....................... 684

CONTENTS

Cell-Free Synthesis of Measles Virus Proteins. JUDY SPRAGUE, LAWRENCE J.ERON, ADELE S. SEIFRIED, AND JULIE B. MILSTIEN* ..... ................. 688

Defective Influenza Viral Ribonucleoproteins Cause Interference. J. MICHAELJANDA AND DEBI P. NAYAK* .............................. ....... ... 697

Bacterial VirusesUnusual Modification of Bacteriophage Mu DNA. STANLEY HATTMAN ....... 468Structural Role of the Polyglutamate Portion of the Folate Found in T4D Bacte-

riophage Baseplate. L. M. KOZLOFF,* L. K. CROSBY, AND C. M. BAUGH .... 497Salmonella Bacteriophage Glycanases: Endorhamnosidases of Salmonella typhi-

murium Bacteriophages. STEFAN B. SVENSON,* JORGEN LONNGREN, NILSCARLIN, AND ALF A. LINDBERG ............... 583

Electron Microscopic Analysis of Partially Replicated Bacteriophage T7DNA. KATHY BAUMAN BURCK, DOUGLAS G. SCRABA, AND ROBERT C.MILLER, JR.* ........................................................... 6

Electrophoretic Characterization of Intracellular Forms of Bacteriophage 4X174DNA: Identification of Novel Intermediates of Altered Superhelix Density.PAUL H. JOHNSON,* MICHAEL J. MILLER, ELIZABETH WILD, SAMUEL V.KELLY, AND LAWRENCE I. GROSSMAN ........ ............................ 629

Fungal VirusesEvolution of Defective-Interfering Double-Stranded RNAs of the Yeast Killer

Virus. WILLIAM P. KANE,* DENNIS F. PIETRAS, AND JEREMY A. BRUENN 692

ErratumIs Abortive Infection by Bacteriophage BF23 of Escherichia coli Harboring Collb

Plasmids due to Cel Klling by Internally Liberated Cohcin Ib? D. J. MC-CORQUODALE, A. R. SHAW, E. E. MOODY, R. A. HULL, AND A. F. MORGAN .. 703

Volume 32 Contents for December 1979 Number 3Animal Viruses

Purification of the JS-3 Isolate of Herpesvirus ovis (Bovid Herpesvirus 4) and SomeProperties of Its DNA. E.-M. DE VILLIERS .............................. 705

Immunochemical Characterization of Epstein-Barr Virus-Associated Early andLate Antigens in n-Butyrate-Treated P3HR-1 Cells. BENGT KALLIN,* JANOSLUKA, AND GEORGE KLEIN ............................................. 710

Regulation of the Primary Expression of the Early Adenovirus TranscriptionUnits. JOSEPH R. NEVINS,* HAROLD S. GINSBERG, J.-M. BLANCHARD, MI-CHAEL C. WILSON, AND JAMES E. DARNELL, JR........................... 727

Alterations in Glycosphingolipid Patterns in a Line of African Green MonkeyKidney Cells Infected with Herpesvirus. EDWARD W. SCHRODER AND JOSEPHM. MERRICK..... 734

Herpes Simplex Virus Glycoproteins: Participation of Individual Herpes SimplexVirus Type 1 Glycoprotein Antigens in Immunocytolysis and Their Correlationwith Previously Identified Glycopolypeptides. B. NORRILD,* S. L. SHORE,AND A. J. NAHMIAS..... 741

gag-Related Polypeptides Encoded by Replication-Defective Avian Oncoviruses.CARL W. RETrENMIER,* STEVEN M. ANDERSON, MARK W. RIEMEN, ANDHIDESABURO HANAFUSA ......................... 749

Analysis of Cellular Integration Sites in Avian Sarcoma Virus-Infected DuckEmbryo Cells. TONA M. GILMER AND J. THOMAS PARSONS* .............. 762

CONTENTS

Protease Required for Processing Picornaviral Coat Protein Resides in the ViralReplicase Gene. ANN C. PALMENBERG,* MARK A. PALLANSCH, AND ROLANDR. RUECKERT ...................................................... 770

Membrane Proteins Specified by Herpes Simplex Viruses. V. Identification of anFc-Binding Glycoprotein. ROBERT B. BAUCKE AND PATRICIA G. SPEAR* ... 779

Stabilization of "A" Particles of Coxsackievirus B3 by a HeLa Cell Plasma Mem-brane Extract. MARY L. MCGEADY AND RICHARD L. CROWELL* ... 790

Polypeptides of Hepatitis B Virus Surface Antigen Produced by a Hepatoma CellLine. PATRICIA L. MARION, FELIX H. SALAZAR, JENNIFER J. ALEXANDER,AND WILLIAM S. ROBINSON* ............................................ 796

5'-Terminal Nucleotide Sequences of the Rauscher Leukemia Virus and GibbonApe Leukemia Virus Genomes Exhibit a High Degree of Correspondence.GERALD G. LOVINGER AND GERALD SCHOCHETMAN*..... 803

Analysis of the DNAs from Seven Varicella-Zoster Virus Isolates. JAMES C.RICHARDS, RICHARD W. HYMAN,* AND FRED RAPP....................... 812

Persistence of Infectious Friend Virus in Spleens of Mice After SpontaneousRecovery from Virus-Induced Erythroleukemia. BRUCE CHESEBRO,* MAR-SHALL BLOOM, KATHY WEHRLY, AND JANE NISHIO ....................... 832

Inactivation of Influenza and Vesicular Stomatitis Virion RNA Polymerase Activi-ties by Photoreaction with 4'-Substituted Psoralens. KUNIo NAKASHIMA,PRANAB K. CHANDA, VICTOR DEUTSCH, AMIYA K. BANERJEE, AND AARONJ. SHATKIN * ............. ........ .... ... 838

Establishment of a C3Hf Mammary Tumor Cell Line Expressing EndogenousMouse Mammary Tumor Virus: Antigenic and Genetic Relationships of ThisVirus with Highly Oncogenic Mouse Mammary Tumor Viruses. LARRY 0.ARTHUR,* GERALD G. LOVINGER, AND GERALD SCHOCHETMAN ..... 852

Restriction Endonuclease Mapping of Unintegrated Proviral DNA of Snyder-Thei-len Feline Sarcoma Virus: Localization of Sarcoma-Specific Sequences.CHARLES J. SHERR,* LouIs A. FEDELE, LUDVIK DONNER, AND LUBOMIR P.TUREK ............................................................... 860

UV Inactivation of the Biological Activity of Defective Interfering Particles Gen-erated by Vesicular Stomatitis Virus. PAULINE H. S. BAY AND M. E. REICH-MANN*............ 876

Correlation Between Epstein-Barr Virus Membrane Antigen and Three Large CellSurface Glycoproteins. BRUCE C. STRNAD,* RUSSELL H. NEUBAUER, HARVEYRABIN, AND RICHARD A. MAZUR............ 885

Cap and Internal Nucleotides of Reovirus mRNA Primers Are Incorporated intoInfluenza Viral ComplementaryRNADuring Transcription In Vitro. MICHELEBOULOY, MAUREEN A. MORGAN, AARON J. SHATKIN, AND ROBERT M. KRUG* 895

Conserved Region of Mammalian Retrovirus RNA. R. KOMINAMI AND M. HA-TANAKA*.... 925

Viable Deletion Mutant of Human Papovavirus BK That Induces Insulinomas inHamsters. SUMIE WATANABE,* KUNITO YOSHIIKE, AKEMI NOZAWA, YASU-HITO YUASA, AND SEIJIRO UCHIDA ..................... 934

Transformation of Primary Rat Kidney Cells by DNA Fragments of WeaklyOncogenic Adenoviruses. REIN DIJKEMA,* BEN M. M. DEKKER, MACHTELDJ. M. VAN DER FELTZ, AND ALEX J. VAN DER EB .......................... 943

Genome Organization of Retroviruses. VI. Heteroduplex Analysis of Ecotropic andXenotropic Sequences of Moloney Mink Cell Focus-Inducing Viral RNA Ob-tained from Either a Cloned Isolate or a Thymoma Cell Line. ROBERT A.BOSSELMAN, LEO J. L. D. VAN GRIENSVEN, MARGUERITE VOGT, AND INDERM. VERMA* .......................................................... 968

CONTENTS

Simian Virus 40 Small t Antigen Is Not Required for the Maintenance of Transfor-mation but May Act as a Promoter (Cocarcinogen) During Establishment ofTransformation in Resting Rat Cells. ROLAND SEIF* AND ROBERT G. MARTIN 979

Retransfornation of a Simian Virus 40 Cell Line, Which Is Resistant to Viral andDNA Infections, by Microinjection of Viral DNA. A. GRAESSMANN, M.GRAESSMANN, W. C. ToPP,* AND M. BOTCHAN ........................... 989

In Vitro Association of Empty Adenovirus Capsids with Double-Stranded DNA.CLARK TIBBETTS* AND CHOU-ZEN GIAM ... .. ..... 995

Isolation of Influenza C Virus Recombinants. VINCENT R. RACANIELLO ANDPETER PALESE*............. ...... .. .. .. ..... ............. 1006

Comparative Study of Different Isolates of Murine Sarcoma Virus. DANIEL J.DONOGHUE,* PHILLIP A. SHARP, AND ROBERT A. WEINBERG.1015

Heteroduplex Analysis of the RNA of Clone 3 Moloney Murine SarcomaVirus. YUEH-HSIU CHIEN, INDER M. VERMA, P. H. DUESBERG, AND NORMANDAVIDSON * .. ... .................. 1028

Herpes Simplex Virus DNA Synthesis in a Partially Purified Soluble Extract fromInfected Cells. PIER F. PIGNATTI,* ENZO CASSAI, AND UMBERTO BERTAZZONI 1033

Inhibition of Influenza C Virus Replication by Actinomycin D, a-Amanitin, and UVIrradiation. THOMAS PETRI, HERBERT MEIER-EWERT, AND RICHARD W.COMPANS*..... 1037

The Nonstructural Component of the Abelson Murine Leukemia Virus PolyproteinP120 Is Encoded by Newly Acquired Genetic Sequences. WIM J. M. VAN DEVEN, FRED H. REYNOLDS, JR., ROBERT P. NALEWAIK, AND JOHN R. STEPHEN-SON . 1041

Peptide Map Comparison of the Proteins of Infectious Bursal DiseaseVirus. PETER DOBOS.1046

Characterization of Intracellular Precursor Polyproteins of Moloney Murine Leu-kemia Virus. V. L. NG, T. G. WOOD, D. D. LYONS, AND R. B. ARLINGHAUS* 1051

Bacterial VirusesComposition and Molecular Organization of Lipids and Proteins in the Envelope of

Mycoplasmavirus MVL2. NOA GREENBERG AND SHLOMO ROTTEM* .. 717Host Transcription in Bacteriophage P22-Infected Salmonella typhimurium.

JAMES M. PIPAS AND ROBERT H. REEVES* ................................ 822In Vivo Methylation of Bacteriophage 4X174 DNA. STANLEY HATTMAN,* CHRIS

GRIBBIN, AND CLYDE A. HUTCHISON III ................................. 845regA Protein of Bacteriophage T4D: Identification, Schedule of Synthesis, and

Autogenous Regulation. THOMAS S. CARDILLO, EDWARD F. LANDRY, ANDJOHN S. WIBERG*........ .... 905

Inhibition of Initiation of Bacteriophage T4 DNA Replication by Perturbation ofEscherichia coli Host Membrane Composition. WAI M. HUANG.917

Characterization of a Bacteriophage Related to R-Type Pyocins. MAKOTO KA-GEYAMA,* TOMOYUKI SHINOMIYA, YOSHIMI AIHARA, AND MIEKO KOBAYASHI 951

Bactericidal Activity of the Tail of Pseudomonas aeruginosa BacteriophagePS17. TOMOYUKI SHINOMIYA* AND SAWAKO SHIGA .. ..... 958

ErratumInhibition of Herpes Simplex Virus-Induced DNA Polymerase Activity and Viral

DNA Replication by 9-(2-Hydroxyethoxymethyl)guanine and Its Triphos-phate. PHILLIP A. FURMAN, MARTY H. ST. CLAIR, JAMES A. FYFE, JANET L.RIDEOUT, PAUL M. KELLER, AND GERTRUDE B. ELION.1057