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 Yulia Dwi Setia

156070100111002

IMPAIRMENT OF THE UBIQUITINPROTEASOMESYSTEM !AUSES DOPAMINER"I! !E## DEATH

AND IN!#USION BODY FORMATION IN$ENTRA# MESEN!EPHA#I! !U#TURES

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Pat%&l&'( )a*i Pa*+i,-&, Di-ea-eDe'e,e*ati. )a*i )&/ai,e&,tai,i,' ,eu*&,

)i -u-ta,-ia ,i'*a /a*- &/ata

Pe,)a%ulua,

'a'al,(a ui3uiti, 4 /*&tea-&e -(-te UPS

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ultu* -el ,eu*&, /a)a 8e,t*al e-e,e/%ali $M *at

Met&)e

$a*iael (a,' )iu+u*

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Ha-il

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#ata(-ti,)&/ai,e*'i ell )eat%9"a'al e,)e'*a)a-i /*&tei,Pee,tu+a, i,lu-i&, &)ie- /ee,'+a+a, /a)a /*&-e-u- a:&,  

/e,i,'+ata, /e,'eata, ui3uiti, )a, a-(,ulei,

UAMe,'%aat U!H  e,u*u,+a, a8aiilita-

)a*i ui3uiti,  e,'%aat )e'*a)a-i /*&tei,elalui UPS

Di-+u-i

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D&/ai,e*'i+ ,eu*&, lei% -e,-iti. /a)ai,%ii-i UPS+ea)aa, &:i)ati8e (a,' -a,'at ti,''i /a)a

)&/ai,e*'i ,eu*&,-  UPS ee*-i%+a,

/*&tei, (a,' eili+i +e*u-a+a, ti,'+at ti,''i /&te,-i -it&t&+-i+ ti,''i

; -(,ulei,Di)e'*a)a-i 26

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e*u-a+a, /a)a UPS )ala e,)e'*a)a-i/*&tei, eili+i /e*a, /e,ti,' /a)a)e'e,e*a-i )a*i )&/ai,e*'i ,eu*&,9a+uula-i /*&tei, )a, /ee,tu+a, #ew(&)( /a)a /a-ie, Pa*+i,-&,

e-i/ula,

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 Te*ia +a-i%