KEY CONCEPT Blood is a complex tissue that transports materials.

red blood cells,white blood cells,and platelets

plasma

Blood is composed mainly of cells, cell fragments, and plasma.

• Whole blood is made up of different materials.– Plasma• 90% H2O- allows for materials to dissolve• Concentrations- diffusion into or out of

blood• Amino acids, glucose, salts, waste,

vitamins, hormones– red blood cells – white blood cells – platelets

Red Blood Cells

• Produced from stem cells in bone marrow• Lose nucleus as they mature• Transport O2 to cells; remove CO2

• O2 binds to hemoglobin proteins

• Dead cells filtered by liver & spleen

• White blood cells fight pathogens and destroy foreign matter.

red blood cell

platelet

white blood cell

• Platelets help form clots that control bleeding.

platelets

fibrin

red blood cell

white blood cell

• Proteins on blood cells determine blood type• Antigens (markers)– proteins on cell’s surface that identify cells as foreign or natural

• Antibodies:– proteins from WBCs to attack invaders

• Will bind to foreign blood types and cause clumps– Float freely in plasma

ABO Blood Groups

Group A blood

• A antigens on the surface of your red blood cells and B antibodies in your blood plasma

Group B blood

• B antigens on the surface of your red blood cells and A antibodies in your blood plasma

Group AB blood

• A and B antigens on the surface of your red blood cells and no A or B antibodies at all in your blood plasma

Group O blood

• No A or B antigens on the surface of your red blood cells but you have both A and B antibodies in your blood plasma

Rh Factors• Rh Factor is another protein

found on blood (like the A and B antigens).

• Rh+ (A+, B+, AB+, O+)– You have the Rh factor

protein in blood– Can receive Rh+ or Rh-

blood (if you have Rh proteins, but are given blood without it, your body will just make more)

• Rh- (A-, B-, AB-, O-)– You don’t have the Rh

factor protein in blood– Only receive Rh- blood

1) Can this work?

• Acceptor

O-

• Donor

AB-

2) Can this work?

• Acceptor

A+

• Donor

A-

3) Can this work?

• Acceptor

AB-

• Donor

B-