The Journal of

Steroid Biochemistry & Molecular Biology Editors -in -chief

J. R. PASQUALINI and R. SCHOLLER

VOLUME

SUBJECT AND

CONTENTS,

AUTHOR INDEX

V o l u m e 51 1994

( ~ Pergamon

The Journal of Steroid Biochemistry and Molecular Biology

E D I T O R S - I N - C H I E F J. R. P a s q u a l i n i and R. S c h o l l e r

Foundat ion for Hormone Research, 26 Boulevard Brune, 75014 Paris, France

H. A d l e r c r e u t z , Hels inki , F i n l a n d M. B e a t o , M a r b u r g / L a h n , G e r m a n y B. G r o n e r , F re ibu rg , G e r m a n y E. G u r p i d e , N e w York, U .S .A. J . -A . G u s t a f s s o n , H u d d i n g e , Sweden E. V. J e n s e n , H a m b u r g , G e r m a n y J. K a t o , Yamanash i -ken , Japan

ASSOCIATE EDITORS

R. J. B. King, Guildford, England M. E. L ippman, Washington, DC, U.S.A. L. Martini , Milan, Italy A. Munck, Hanover, NH, U.S.A. B. W. O'Malley, Houston, TX, U.S.A. D. O. Tort, Rochester, MN, U.S.A.

A. Aakvaag, Bergen, Norway A. S. Bhatnagar, Basel, Switzerland R. Bouillon, Leuven, Belgium A. Brodie, Baltimore, U.S.A. M. L. Casey, Dallas, U.S.A. K. J. Catt, Bethesda, U.S.A. J. A. Cidlowski, Chapel Hill, U.S.A. P. D. Darbre, Reading, England G. Daxenbichler, Innsbruck, Austria E. R. DeSombre, Chicago, U.S.A. B. N. Diaz-Chico, Las Palmas, Spain R. B. Dickson, Washington, U.S.A. M. Dowsett, London, England M. L. Dufau, Bethesda, U.S.A. D. P. Edwards, Denver, U.S.A. H. A. Eriksson, Stockholm, Sweden K. Fotherby, London, England J. W. Funder, Prahran, Australia G. Greene, Chicago, U.S.A. H. Gronemeyer, Strasbourg, France H. Honjo, Kyoto, Japan K. B. Horwitz, Denver, U.S.A.

CORRESPONDING EDITORS I. Huhtaniemi, Turku, Finland V. H. T. James, London, England V. C. Jordan, Chicago, U.S.A. B. S. Katzenellenbogen, Urbana, U.S.A. A. M. Kaye, Rehovot, Israel E. R. de Kloet, Leiden, The Netherlands H. J. Kloosterboer, Oss, The Netherlands F. Labrie, Quebec, Canada S. Liao, Chicago, U.S.A. V. B. Mahesh, Augusta, U.S.A. B. S. McEwen, New York, U.S.A. H. Michna, Berlin, Germany E. Milgrom, Le Kremlin-Bic&re, France W. R. Miller, Edinburgh, Scotland J. Miiller, Zurich, Switzerland L. J. Murphy, Winnipeg, Canada A. Naray-Fejes-Toth, Hanover, U.S.A. M. I. New, New York, U.S.A. A. W. Norman, Riverside, U.S.A. T. Ojasoo, Montrouge, France M. G. Parker, London, England G. P6rez-Palacios, Mexico City, Mexico

W. B. Pratt, Ann Arbor, U.S.A. J. P. Raynaud, Paris, France R. Renkawitz, Giessen, Germany H. Rochefort, Montpellier, France G. Rousseau, Brussels, Belgium B. Sato, Osaka, Japan M. Serio, Florence, Italy E. ,R. Simpson, Dallas, U.S.A. J. Sj6vall, Stockholm, Sweden L. Stfirka, Prague, Czech Republic J. F. Strauss III, Philadelphia, U.S.A. R. L. Sutherland, Darlinghurst, Australia J. R. Tata, London, England W. Taylor, Tynemouth, England P. Tuohimaa, Tampere, Finland G. Verhoeven, Leuven, Belgium A. Vermeulen, Ghent, Belgmm R. Vihko, Oulu, Finland C. A. Villee, Boston, U.S.A. A. E. Wakeling, Macclesfield, England C. R. Wira, Hanover, U.S.A.

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Editor ia l Addresses

S tero id Nomenc la tu re

Edi tor ia l A n n o u n c e m e n t

General Review B. R. Westley and F. E. B. May

Papers Jon Milhon, Kulwant Kohli

and Michael R. Stal lcup

Chr i s t i an C. M6ws, Thomas Preiss , Emi ly P. Slater, Xinan Cao, C. Pe t e r Verr i jzer , Pe t e r C. Van Der Vliet and Miguel Beato

Joop D. van den Berg, Lou A. Smets , Kevin A. Hutchison, Henny van Rooij and Mar ion M. van den Elshout

H. Watson, S. Franks and R. C. Bonney

D. Cousty-Ber l in , B. Bergaud, M. C. Bruyant , T. B a t t m a n n , C. Branche and D. Ph i l ibe r t

Lena Sahlin, Gunna r Nors ted t and H~kan Eriksson

Nikos Antonakis , Vassilis Georgoulias, Andrew N. Margior is , Chris tos S tourna ras and Achille Gravanis

H6ctor Con t re ras and Ana Mar ia Ronco

Pie ra Rebuffat , Krzysz to f W. Nowak, Cinzia Tortorel la , Francesco G. Musajo, Giuseppe Got tardo, Giuseppina Mazzocchi and Gastone G. Nussdor fe r

Paola Negri -Cesi and Marcel la Mot ta

Eva Ax6n, Tomas B e r g m a n and Kjell Wikvall

L. Giri ja Devi, M. Basheer A h m a d and S. Shivaii

Sergey A. Krupenko, Natalia I. Krupenko and Ben jamin J. Danzo

A n n o u n c e m e n t

Edi tor ia l A n n o u n c e m e n t

Review Zygmunt Krozowski

Papers Simon W. Law, Ede M. Apostolakis,

Pa t r ick J. Samora , Ber t W. O'Malley and James H. Clark

Cars t en Calberg, Ida S. Mathiasen , Jean-Hi la i re Saura t and Lise B inderup

L I S T

V

ix

xiii

O F C O N T E N T S

O C T O B E R

1 Role of insulin-like growth factors in steroid modulated proliferation

11 Genetic analysis of the N-terminal end of the glucocorticoid receptor hormone binding domain

21 Two independent pathways for transcription from the MMTV promoter

33

41

47

57

67

73

81

High levels of non-activated receptors in glucocorticoid-sensitive $49 ~ mouse lymphoma cells incubated with dexamethasone

The epidermal growth factor receptor in the human endometrial adenocarcinoma cell line HEC-1-B

Preliminary pharmacokinetics and metabolism of novel non-steroidal antiandro- gens in the rat: relation of their systemic activity to the formation of a common metabolite

Androgen regulation of the insulin-like growth factor-I and the estrogen receptor in rat uterus and liver

In vitro differential effects of the antiglucocorticoid RU486 on the release of lymphokines from mitogen-activated normal human lymphocytes

Leydig cell heterogeneity as judged by quantitative cytochemistry of 3fl-hydroxy- steroid dehydrogenase activity in individual rat Leydig cells

Evidence that endogenous vasoactive intestinal peptide (VIP) plays a role in the maintenance of the growth and steroidogenic capacity of rat adrenal zona glomerulosa

89 Androgen metabolism in the human prostatic cancer cell line LNCaP

97 Microsomal 25-hydroxylation of vitamin D 2 and vitamin D 3 in pig liver

107

115

125

131

137

Secretory proteins of the hamster cervix, uterus and oviduct: the effects of estradiol, progesterone and testosterone on the proteins secreted into the medium

Interaction of sex hormone-binding globulin with plasma membranes from the rat epididymis and other tissues

N O V E M B E R

The short-chain alcohol dehydrogenase superfamily: variations on a common theme

Hormonal regulation of hypothalamic gene expression: identification of multiple novel estrogen induced genes

The 1,25-dihydroxyvitamin D3 (VD) analogues MC903, EB1089 and KH1060 activate the VD receptor: homodimers show higher ligand sensitivity than heterodimers with retinoid X receptors

iii

iv

Daniele Szapary, Therese Barber , Nancy K. Dwyer, E. Joan Blanchet te -Mackie and S. Stoney Simons Jr

Kathleen E. Mach and H. R ichard Fevold

R. Mukherjee, L. Jow, D. Noonan and D. P. McDonnel l

Keiko Sugimoto, Jacques S imard , Darrow E. Haagensen and Fernand Labrie

M. Massobrio, M. Migliardi , P. Cassoni, C. Menzaghi, A. Revelli and G. Cenderell i

Gerardo Piroli , Analia E. Lima, Graciela Diaz-Torga and Alejandro F. De Nicola

Daniel G. Carr izo, Ana M. Rastr i l la , Carlos M. Telleria and Luis I. Aguado

M. A. Glasier, J. P. Wiebe and R. Hobkirk

B. Bi ro-Sauveur , C. Eeckhoutte , J.-F. Sutra, C. Call~ja, M. Alvinerie and P. Gal t ier

Pe t e r H. Jellinck, Anne -Mar i e Newcombe , P. Gek Forkert and Charles P. Mar tucci

Book Reviews

Announcements

143

List of Contents

Microtubules are not required for glucocorticoid receptor mediated gene induction

149 Post-transcriptional action of ACTH in the control of P450c17 expression in rabbit adrenal glands

157 Human and rat peroxisome proliferator activated receptors (PPARs) demonstrate similar tissue distribution but different responsiveness to PPAR activators

167 Inverse relationships between cell proliferauon and basal or androgen-stimulated apolipoprotein D secretion in LNCaP human prostate cancer cells

175 Steroid gradients across the cancerous breast: an index of altered steroid metabolism in breast cancer?

183 Biochemical parameters in the anterior pituitary during the course of tumorigenesis induced by diethylstilbestrol treatment

191 Androstenedione stimulates progesterone production in corpora lutea of pregnant rats: an effect not mediated by oestrogen

199 Progesterone metabolism by guinea pig intrauterine tissues

209 Consequences of challenge infections with Faseiola hepatzca on rat liver P450- dependent metabolism of sex hormones

219 Distinct forms of hepatic androgen 6fl-hydroxylase induced in the rat by indole-3- carbinol and pregnenolone carbonitrile

227

I

Editorial Jorge R. Pasqual in i

General Review Anait S. Levenson and V. Craig Jordan

Papers M o h a m e d K. Mohamed , Lin Tung,

Glenn S. Takimoto and Kathryn B. Horwitz

David C. Spink, Car r ie L. Hayes, Nina R. Young, Maro Chris tou, Thomas R. Sut ter , Colin R. Jefcoate and John F. Gier thy

Bruno Varriale and Ismene Serino

U. Kuhnle, U. Keller, D. Arman in i , J. Funder and Z. Krozowski

M. Br6nneg/trd, M. Ottosson, J. B66s, C. Marcus and P. Bj6rntorp

Carol J. Belfiore, Dean E. Hawkins, Milo C. Wil tbank and Gordon D. Niswender

Gian Paolo Rossini and Claudia Malagut i

Sha lom B a r - A m i

D E C E M B E R

V Breast cancer, present and future

229 Transfection of human estrogen receptor (ER) cDNA into ER-negative mammalian cell lines

241

251

259

267

The leucine zippers of c-fos and c-jun for progesterone receptor dimerization: A-dominance in the A/B heterodimer

The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on estrogen metabolism in MCF-7 breast cancer cells: evidence for induction of a novel 17fl-estradiol 4-hydroxylase

The androgen receptor mRNA is up-regulated by testosterone in both the Harderian gland and thumb pad of the frog, Rana esculenta

Immunofluorescence of mineralocorticoid receptors in peripheral lymphocytes: presence of receptor-like activity in patients with the autosomal dominant form of pseudohypoaldosteronism, and its absence in the recessive form

275 Lack of evidence for estrogen and progesterone receptors in human adipose tissue

283 Regulation of cytochrome P450sc c synthesis and activity m the ovine corpus luteum

291

299

Nanomolar concentrations of untransformed glucocorticoid receptor m nuclei of intact cells

Increasing progesterone secretion and 3fl-hydroxysteroid dehydrogenase activity of human cumulus cells and granulosa-lutein cells concurrent with successful fertilization of the corresponding oocyte

Aarno Hautanen, Matt i M/intt~iri, 307 Gemfibrozil treatment is associated with elevated adrenal androgen, androstanediol Vesa Manninen and Herman Adlercreutz glucuronide and cortisol levels in dyshpidemic men

Lis t of Con ten t s v

J a r m i l a ~ulcov~i, M. Macek, D. Chudoba , W. Hubl , M. Hill and L. S t h r k a

Rapid Communication R. Fra i r i a , N. F o r t u n a t i , A. Revelli , D. Guidet t i ,

S. CavagliA and M. Massobr io

315 Amniotic fluid 17-hydroxyprogesterone in early pregnancy

319 Binding of sex steroid binding protein to plasma membranes of human testis

Book Reviews 323

S U B J E C T I N D E X ACTH

post-transcriptional action of, in the control of P450c17 expression in rabbit adrenal glands, 149 Adipose tissue

lack of evidence for estrogen and progesterone receptors in human, 275 Adrenal zona glomerulosa

effect of endogenous vasoactive intestinal peptide on maintenance of growth and steroidogenic capacity of, in rat, 81

Alcohol dehydrogenase the short-chain, superfamily, 125

Amniotic fluid 17/~-hydroxyprogesterone of, in early pregnancy, 315

Androgen(s) elevated adrenal, levels in dyslipidemic men, 307 metabolism of, in the human prostatic cancer cell line LNCaP, 89 receptor

mRNA of, is up-regulated by testosterone in both Harderian gland and thumb pad of the frog Rana esculenta, 259

regulation of insulin-like growth factor-I by, in rat uterus and liver, 57 Androstanediol glucuronide

elevated levels of, associated with gemfibrozil treatment in dyslipidemic men, 307 Androstenedione

stimulation of progesterone production by, in corpora lutea of pregnant rat, 191 Anterior pituitary

biochemical parameters in the, during tumorigenesis induced by diethylstilbestrol treatment, 183 Anti-androgen(s)

pharmacokinetics and metabolism of novel non-steroidal, in the rat, 47

Breast cancer effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on estrogen metabolism in MCF-7, cells, 251 steroid gradients across the cancerous breast: an index of altered steroid metabolism in, 175

Corpus luteum regulation of cytochrome P450scc synthesis and activity in the ovine, 283

Cortisol elevated levels of, associated with gemfibrozil treatment in dyslipidemic men, 307

Cytochrome P450scc regulation of, synthesis and activity in the ovine corpus luteum, 283

Dexamethasone high levels of non-activated receptors in glucocorticoid-sensitive S49wt mouse lymphoma cells incubated with,

33 Diethylstilbestrol

biochemical parameters in the anterior pituitary during tumorigenesis induced by diethylstilbestrol treatment, 183

1,25-Dihydroxyvitamin D3 receptor

activated by analogues MC903, EB1089 and KH1060, 137

Endometrial adenocarcinoma epidermal growth factor receptor in the human, cell line HEC-1-B, 41

Epidermal growth factor receptor

in the human endometrial adenocarcinoma cell line HEC-1-B, 41 vii

viii Subject Index

Epididymis interaction of sex hormone-binding globulin with plasma membranes from the, of rat, 115

17fl-Estradiol 4-hydroxylase induction of, by 2,3,7,8-tetrachlorodibenzo-p-dioxin in MCF-7 breast cancer cells, 251

Estradiol effects of, on the proteins secreted by the hamster cervix, uterus and oviduct, 107

Estrogen(s) multiple novel, induced genes in the hypothalamus, 131 receptor(s)

androgen regulation of, in rat uterus and liver, 57 lack of evidence for, in human adipose tissue, 275 transfection of human, cDNA into ER-negative mammalian cell lines, 229

Estrogen receptor cDNA transfection of human, into ER-negative mammalian cell lines, 229

c@s leucine zippers of, for progesterone receptor dimerization, 241

Gemfibrozil treatment of dyslipidemic men with, 307

Gene(s) hormonal regulation of hypothalamic, expression: identification of multiple novel, induced by estrogen, 131 microtubules are not required for glucocorticoid receptor mediated, induction, 143

Glucocorticoid(s) receptor(s)

genetic analysis of the N-terminal end of the, hormone binding domain, 11 microtubules are not required for, mediated gene induction, 143 nanomolar concentrations of untransformed, in nuclei of intact cells, 291 non-activated, in S49wt mouse lymphoma cells, 33

Hormone binding domain genetic analysis of the N-terminal end of the glucocorticoid receptor, 11

6fl-Hydroxylase distinct forms of hepatic androgen, induced in the rat, 219

25-Hydroxylation microsomal, of vitamins D2 and D3 in pig liver, 97

17fl-Hydroxyprogesterone amniotic fluid, in early pregnancy, 315

3fl-Hydroxysteroid dehydrogenase activity in individual rat Leydig cells, 73 increasing, activity of human cumulus cells and granulosa lutein cells, 299

Hypothalamus hormonal regulation of gene expression in, and identification of multiple novel estrogen induced genes, 131

Insulin growth factor(s) androgen regulation of the, -I in rat uterus and liver, 57 role of, in steroid modulated proliferation, 1

c-jun leucine zippers of, for progesterone receptor dimerization, 241

Leydig cells 3fl-Hydroxysteroid dehydrogenase activity in individual rat, 73

Lymphocytes in vitro differential effects of the antiglucocorticoid RU486 on the release of lymphokines from mitogen-

activated normal human, 67 immunofluorescence of mineralocorticoid receptors in peripheral, 267

Subject Index ix

Lymphokines release of, from mitogen-activated normal human, 67

Mammalian cell lines transfection of human estrogen receptor cDNA into ER-negative, 229

MCF-7 cells effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin in, 251

Mineralocorticoid(s) receptor(s)

immunofluorescence of, in peripheral lymphocytes, 267 MMTV promoter

transcription from the, by two independent pathways, 21 mRNA

up-regulation of androgen receptor, by testosterone in both Harderian gland and thumb pad of the frog Rana esculenta, 259

P450c17 expression post-transcriptional action of ACTH in the control of, in rabbit adrenal glands, 149

Peroxisome proliferator activated receptors (PPARs) demonstration of similar tissue distribution of human and rat, but different responsiveness to PPAR activators,

157 Progesterone

effects of, on proteins of the hamster cervix secreted into the medium, 107 metabolism of, by guinea pig intrauterine tissues, 199 receptors

lack of evidence for, in human adipose tissue, 275 leucine zippers of c-fos and c-jun for, dimerization, 241

stimulation by androstenedione of, production in corpora lutea of pregnant rat, 191 Prostatic cancer cell line LNCaP

androgen metabolism in the, 89 Pseudohyperaldosteronism

presence of receptor-like activity in the autosomal dominant form and absence in the recessive form of, 267

Receptor(s) epidermal growth factor

in the human endometrial adenocarcinoma cell line HEC-1-B, 41 estrogen(s)

androgen regulation of, in rat uterus and liver, 57 lack of evidence for, in human adipose tissue, 275 transfection of human, cDNA into ER-negative mammalian cell lines, 229

peroxisome proliferator activated (PPARs) human and rat, demonstrate similar tissue distribution but different responsiveness to PPAR activators, 157

progesterone lack of evidence for, in human adipose tissue, 275 leucine zippers of c-fos and c-jun for, dimerization, 241

glucocorticoid genetic analysis of the N-terminal end of the, hormone binding domain, 11 high levels of non-activated, in $49 wt mouse lymphoma cells incubated with dexamethasone, 33 microtubules are not required for, mediated gene induction, 143 nanomolar concentrations of untransformed, in nuclei of intact cells, 291

mineralocorticoid immunofluorescence of, in peripheral lymphocytes, 267

RU 486 in vitro differential effects of, on the release of lymphokines from mitogen-activated normal human

lymphocytes, 67

Sex hormone-binding globulin interaction of, with plasma membranes from the rat epididymis and other tissues, 115

x Subject Index

Sex steroid binding protein (SBP, SHBG) binding of, to plasma membranes of human testis, 319

Sex hormones consequences of challenge infections with fasciola hepatica on rat liver P450-dependent metabolism of, 209

Steroid(s) gradients across the cancerous breast, 175 role of IGFs in, modulated proliferation, 1

Testis binding of sex steroid binding protein (SBP, SHBG) to plasma membranes of human, 319

Testosterone effects of, on proteins of the hamster cervix secreted into the medium, 107 up-regulation of the androgen receptor mRN A by, in both Harderian gland and thumb pad of the frog, Rana

esculenta, 259 2,3,7,8-Tetrachlorodibenzo-p-dioxin

effects of, on estrogen metabolism in MCF -7 breast cancer cells, 251 Transcript ion

two independent pathways for, from the M M T V promoter, 21

Uterus progesterone metabolism by tissues in, of the guinea pig, 199

Vasoactive intestinal peptide (VIP) effects of endogenous, on growth and steroidogenic capacity of rat adrenal zona glomerulosa, 81

Vitamins D 2 and D 3

microsomal 25-hydroxylation of, in pig liver, 97

We would like to express our deep thanks to the following people for their kind collaboration in reviewing papers for The Journal of Steroid Biochemistry and Molecular Biology:

Drs R. W. Brown, Edinburgh, Scotland; G. Chetrite, Paris, France; R. Clarke, Washington, U.S.A.; C. L. Densmore, Texas, U.S.A.; C. R. W. Edwards, Edinburgh, Scotland; G. L. Hammond , Ontario, Canada; J. W. Honour, London, England; E. Johnson, Victoria, Australia; P. S. Kalra, Gainesville, U.S.A.; J. A. Katzenellenbogen, Urbana, U.S.A.; S. Kikuyama, Tokyo, Japan; C. Knabbe, Hamburg, Germany; K. Lee, London, England; W. C. Lichstensteiger, Zurich, Switzerland; J. G. Liehr, Washington, U.S.A.; N. MacLusky, Ontario, Canada; B. M. Markaverich, Texas, U.S.A.; J. I. Mason, Dallas, U.S.A.; C. Monder, New York, U.S.A.; P. H. Petra , Seattle, U.S.A.; D. Philibert , Romainville, France; M. J. Reed, London, England; J.-M. Renoir, Bicetre, France; F. F. G. Rommer ts , Rotterdam, The Netherlands; M. G. Rowlands, Sutton, England; T. Saruta, Tokyo, Japan; G. Semenza, Zurich, Switzerland; R. J. Sherins, Fairfax, U.S.A.; P. M. Stewart, Birmingham, England; D. B. Tully, Chapel Hill, U.S.A.; Van Luu The, Quebec, Canada; C. K. W. Watts, Sydney, Australia; P. Weisz-Carrington, Richmond, U.S.A.; P. C. White, New York, U.S.A.

A U T H O R I N D E X

Adlercreutz H., 307 Aguado L. I., 191 Ahmad M. B., 107 Alvinerie M., 209 Antonakis N., 67 Apostolakis E. M., 131 Armanini D., 267 Ax6n E., 97

Bar-Ami S., 299 Barber T., 143 Battmann T., 47 Beato M., 21 Belfiore C. J., 283 van den Berg J. D., 33 BergaudB., 47 Bergrnan T., 97 Binderup L., 137 Biro-Sauveur B., 209 Bj6rntorp P., 275 Blanchette-Mackie E. J., 143 Bonney R. C., 41 B66s J., 275 Branche C., 47 Br6nneg~rd M., 275 BruyantM. C., 47

Calberg C., 137 Call6ja C., 209 Cao X., 21 Carrizo D. G., 191 Cassoni P., 175 Cavagli:i S., 319 Cenderelli G., 175 Christou M., 251 Chudoba D., 315 Clark J. H., 131 Contreras H., 73 Cousty-Berlin D., 47

Danzo B. J., 115 De Nicola A. F., 183 Devi L. G., 107 Diaz-Torga G., 183 Dwyer N. K., 143

Eeckhoutte C., 209 van den Elshout M. M., 33 Eriksson H., 57

Fevold H. R., 149 Forkert P. G., 219 Fortunati N., 319 Frairia R., 319 Franks S., 41 Funder J., 267

Galtier P., 209 Georgoulias V., 67 Gierthy J. F., 251 Glasier M. A., 199 Gottardo G., 81 Gravanis A., 67 Guidetti D., 319

Haagensen D. E., 167 Hautanen A., 307 Hawkins D. E., 283 Hayes C. L., 251 Hill M., 315 Hobkirk R., 199 Horwitz K. B., 241 Hubl W., 315 Hutchison K. A., 33

Jefcoate C. R., 251 Jellinck P. H., 219 Jordan V. C., 229 Jow L., 157

Keller U., 267 KohliK., 11 Krozowski Z., 125, 267 KrupenkoN. I., 115 Krupenko S. A., 115 KuhnleU., 267

Labile F., 167 Law S.W., 131 LevensonA. S., 229 Lima A. E., 183

Macek M., 315 Mach K. E., 149 Malaguti C., 291 Manninen V., 307 M/intt/iri M., 307 Marcus C., 275 Margioris A. N., 67 Martucci C. P., 219 Massobrio M., 175, 319 Mathiasen I. S., 137 May F. E. B., 1 Mazzocchi G., 81 McDonnell D. P., 157 Menzaghi C., 175 Migliardi M., 175 Milhon J., 11 Mohamed M. K., 241 Motta M., 89 M6ws C. C., 21 Mukherjee R., 157 Musajo F. G., 81

Negri-Cesi P., 89 Newcombe A.-M., 219 Niswender G. D., 283 Noonan D., 157 Norstedt G., 57 Nowak K. W., 81 Nussdorfer G. G., 81

O'Malley B. W., 131 Ottosson M., 275

Philibert D., 47 Piroli G., 183 Preiss T., 21

Rastrilla A. M., 191 Rebuffat P., 81 Revelli A., 175, 319 Ronco A. M., 73 van Rooij H., 33 Rossini G. P., 291

Sahlin L., 57 Samora P. J., 131 Saurat J.-H., 137 Serino I., 259 Shivaji S., 107 Simard J., 167 Simons S. S. Jr, 143 Slater E. P., 21 Smets L. A., 33 Spink D. C., 251 Stallcup M. R., 11 St~irka L., 315 Stournaras C., 67 Sugimoto K., 167 ~ulcov~i J., 315 Sutra J.-F., 209 Sutter T. R., 251 Szapary D., 143

Takimoto G. S., 241 Telleria C. M., 191 Tortorella C., 81 Tung L., 241

Van Der Vliet P. C., 21 Varriale B., 259 Verrijzer C. P., 21

Watson H., 41 Westley B. R., 1 Wiebe J. P., 199 Wikvall K., 97 Wiltbank M. C., 283

Young N. R., 251

xi