ljekovite masti

8/16/2019 Ljekovite Masti

1/20

JU MEDICINSKA ŠKOLA U ZENICI Školska godina: 2014/201

M A T U R S K I R A D

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Farmaceutske tehnologije sa kozmetologijom

!EMA: L"#ko$i%# &as%i '(ng(#n%a)

M#n%o*: &*+ ,-+ .i n"a K*( ki U #ni a: Dalila D$i3a


2/20

Z E N I C A 201 + 5odin#

SADRŽAJ1. UVOD............................................................................................................... 32. BEZVODNE PODLOGE.......................................................................................4

2.2 PODLOGE TIPA PRAVIH MASTI – GLICERIDI....................................................62.1 APSORPCIONE BAZE..................................................................................82.2 SILIKONI.....................................................................................................8

3. PODLOGE SA VODOM.......................................................................................83.1 KREMOVI – Emu !"#$ %&'()u #$....................................................................*3.2 KREMOVI – Emu !"#$ u #$)%&'(..................................................................1+

4. PODLOGE RASTVORL,IVE U VODI....................................................................114.1 POLIETILENGLIKOLI..................................................................................124.2 ORGANSKI GELOVI...................................................................................124.3 NEORGANSKI GELOVI...............................................................................13

-. IZBOR PODLOGA ZA L,EKOVITE MASTI...........................................................136. IZRADA L,EKOVITIH MASTI..............................................................................14

6.1 MASTI TIPA RASTVORA.............................................................................146.2 MASTI TIPA SUSPENZI,A...........................................................................146.3 MASTI TIPA EMULZI,A...............................................................................14

. ISPITIVAN,E L,EKOVITIH MASTI........................................................................1-6+ LITERATURA....................................................................................................1

2


3/20


4/20

9('( $ 0(0& $ 0( 9&;u m&7(#u & (% #( " (0(9 ? m< ( 9(&5 #$0#( $ m( " m&7( =" " 4+ C m( (9& & 5u@ ( #$9&%" u u5 (0:u '( =" ( u5 (0:( "m( ( 5u0"

$7(5"# 9" $ $9( .S"7&%"0$ !( #$9&%" $ m( " – 5&' & $ u 5& ( (%u " & &="0(m( %7 &$ $7& $0$ u5 (0:$. T& u u #"9&%&'":"< ( 9& & "< m( 0$ 9" $ "0$< $ 7"%"@" m( 0" 9" $ "0( ( 0";"m " %"@"m m&0& " 5& " "'7&9 " 0"m ( 9& & "m(<

"'7&9& &"'"< m( 0( u #(< 57"7&'0$m( " " ' .L#$9&%" $ m( " m& u ('7;(%( " #$'0u " " %"@$ #$9&%" " u5 (0:" 9$ $0( (!$ u&' &%(7(#u> 5&' &!". T( 5&' & ( u;" 9(& 0& ( #$9&%" "u5 (0:"< ( 5&' & $ !( #$9&%" $ m( " %7 (%(#u $ u 3 7u5$1. BEZVODNE PODLOGE2. PODLOGE SA VODOM3. PODLOGE RASTVORL,IVE U VODI

2. BEZVODNE PODLOGE

U =$!%&'0$ 5&' & $ 5('(#u ( 5&' & $ ( u #"9&%&'":"m( = 5&' & $ ( ":$7"'"m( : (5 &75:"&0$ =(!$ ' " "9&0"

2.1 PODLOGE SA UGLJIKOVODICIMA

K(& "7&%"0$ !( "!7('u 5&' & ( ( u #"9&%&'":"m( 9&7" $ $V( $ "0um ( =um " (%um< P(7(F0um " u"'um< P(7(F0um & "'um " P ( "=(!$. O%& u %" &9& m& $9u (70( #$'"0#$0#( u #"9&%&'"9(< "#( $9&0!" $0:"#( 97$>$ &' $ 0$ '& %7 $. T& 0(m &m& u>(%( '(9&m="0(:"#&m u 7(! " " "m &m#$7"m( '&="#$m& 5&' & $ ;$ #$0$

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5/20

9&0!" $0:"#$. K('( u &%$ 5&' & $ '&=7& 57$ "@>$0$ &0$ u (=" 0$ " & #$(%0( 9(7(9 $7" "9( 5&' & ( ( u #"9&%&'":"m(.

VAZELIN /V( $ "0um – 57$ "@>$0(< 5& u %7 ( m#$ ( u #"9&%&'"9($0( %7 ( m#$ (57$ $;0& !( ">$0" u #"9&%&'"9( 9" $ '&="#(#u '$ " (:"#&m 0( $. %7 "5(7(?0 &5" $ 0( $m5$7( u7" &' -+ - C. K&7" " $ !( & %7@>(%(0#$9&0!" $0:"#$ 0$9" 5&' & (< !( "!7('u %#$@ ( 9& %(!$ "0(< 9(& !(m#$0(%& 9( u 9&!m$ " 9"m 57$5(7( "m( " '. D& (!" u 9&:9(m(.

-


6/20

PLASTI BAZE /B$!%&'0$ 5&' & $ – %#$@ ( 9" 57&"!%&'" '&="#$0"m"#$@(0#$m *-J m"0$7( 0" u #( ( -J %7 " 5& "$ " $0 "9& (. P&9&0!" $0:"#" 5 ( " =(!$ u " 0$ %(!$ "0u< &m& $0$ u< 0$u 7( 0$ " 0$"7" "7(#u 9&;u.

O &="0$ 5&' & ( ( u #"9&%&'":"m( (=" 0$ u 0$ u;$ 0u (#(0#$m 9&m5( "=" 0$ u ( 9&7& %"m (9 "%0"m u5 (0:(m( 5& &'0$ u !( &0$ (9 "%0$ u5 (0:$ 9"m( 0$ 5&!0(#$m&& &="0$ " (=" 0& 7$ ( "%0& #$ "0$ 5&' & $

N$'& (:" 0$ 57&'"7u u 9&;u< (m& %(7(#u 5&%7@"0 9" &m& $0" m& u !( %&7" " 5&7$ 0( 9&;" 0$ 57"m(#u %&'u 57 #(#u " m( $ $@9& $ 9"'(#u ( 9&;$

2.2 PODLOGE TIPA PRAVIH MASTI – GLICERIDI

P&' & $ &%& "5( 5& &'0$ u !( "!7('u m( " ( "5& & u=" 0"mu5 (0:(m(< 9(& @ & u #&' " '$7"%( "< ( ":" 0( 9" $ "0(< um5&7 " '7u ".S"7&%"0$ !( "!7('u – O%( 7u5( &=u %( ( " (% 0"! 57"7&'0" " "0 $ 9"57&"!%&'( 9" $ '(0( 7"#$ 9& (m" 9&7" $ 9(& 5&' & $. V"@$ $ 9&7" $9(& '&'(:" '7u "m 5&' & (m(9(& !(m(@>u#u>( 7$' %(. R(0"#$ 9(&5&' & ( " #&@ u%"#$9 u 0$9"m (7"m 7$:$5 u7(m( 0( (!" $ %"0# 9( m( .

SVINJSKA MAST K&0!" $0:"#( &%$ m( " !(%" " &' $m5$7( u7$< (9& &9 "'"7( " u;$ 0$.

6


7/20

N"#$ u%"#$9 9&0 (0 0& ( (%(< !( & #$ '(0( !(m#$0#u#u 7" ":$7"'" (!( ">$0"m %"@"m m( 0"m 9" $ "0(m(< 057. M" & 812< 9" 57$' (% #(7" ":$7"' !( ">$0" m( 0" 9" $ "0( 9$ "m(#u &' 8 12 u #"9&%" ( &m(.

MASNA I BILJNA ULJA K&7" $ $ u 9&m="0(:"#" ( '7u "m 5&' & (m( '( &m$9@(#u9&0!" $0:"#u 5&' & $< '( '&="#$m& $mu !"#u (9@$ 7(!m(!"%u< u #$ '(#$m( 0"#u 5&' & u< m(0#u#$ " u@u#u>$ '$# %& 5&' & $. M( 0( u #( $9&7" $ !( "!7('u 9&!m$ " 9" 57$5(7( ( /=('$m&%&< (0$0& u #$ < ( 0$9('$ 9&7" $ " 9(& %$ "9u um !( u 5$0!"#$.U #( $ '"#$ $ 0( u@"%( 5& u u@"%( 0$ u@"%(U9& "9& #$ u u #u %$>" =7 '%&%( $0 0" %$!( u 0$!( ">$0"m m( 0"m9" $ "0(m( ('( #$ 7"#$ & u@"%&m u #u (0$0& " 7":"0u &%& u #$< '&9 u0$ u@"%( =('$m&%&< m( "0&%& " u #$ 9"9"7"9"#(. M( 0"m u #"m( $ m&7(#u&'7$'" " 9&0 (0 $ 9$ 9(7(9 $7"@u " &m& u>(%(#u 57&:#$0u %7"#$'0& "%(9& m( 0& u #( – 9" $ "0 9"< (5&0"?9(:"&0"< #&'0" " 5$7&9 "'0" =7. D(=" $ 5&%$>( ( (=" 0& u #( '&'(#$ $ (0 "&9 "'(0 ( ( &9& $7&/%" (m"0 E . N( (=" 0& u #( u ">u " u &%" 5&' 9"m $ u%(#u< ( " 57(%0&u%(0#$ 5&'7(!um"#$%( 5u0u !( %&7$0u =&:u 0( ('0&m " u &m m#$ u<!(@ ">$0& &' %#$ & ".

VOSKOVI ="#$ " %& (9 /C$7( ( =( ;u " %& (9 /C$7( (%(S%" %& 9&%" u $ 7" %"@" m( 0" 9" $ "0(< m&0& "'7&9 " 0" ( 9& & ( (m( 0"m 9" $ "0(m(. S (=" 0" u " m& u &9 "'"7( " $9 0(9&0 'u & (#(0#(.V& 9&%" "m(#u %7 u 9&0!" $0:"#u " 57"m#$0#u#u $ !( & %7@>(%(0#$5&' & $ '& ;$ #$0$ 9&0!" $0:"#$.

LANOLIN /C$7( (0($


8/20

S( " $ "! m#$@(%"0$ 7(!0" $ $7( %"@" ( 9& & ( ( %"@"m m( 0"m9" $ "0(m(< ( &' ( 9& & ( 9" u (!$ u ( (% (0& "0( 0(#%(;0"#" u& $ $7& " "!& & $ $7& – 57"7&'0" $mu ( &7". O%" ( 9& & " '(#u (0& "0u%$ "9u 5& &=0& $mu &%(0#( %&'$ 7('$>" $mu !"#u "5( %&'()u #$.L(0& "0 (9& &9 "'"7( 5( #$ "09&m5( "=" (0 ( u5 (0:(m( 9$ 5&' "#$;u&9 "'(:"#" 9(& @ & u (0 "="& ":". Im( 0$57"#( (0 m"7" < (#(0#$m 57&m"#$0"=u< "m( ;" (%u 9&0!" $0:"#u " 5&' & (m( '(#$ #$5 #"%$ & &="0$. K&' 0$9"#u'" m&;$ "!(!%( " ( $7 "#u. D(0( $ 9&7" " " (% 0"! '$7"%( ( (0& "0( 9(&0#$ &%$ !(m#$0$< 5&=& #@(0$ u 0$9$ & &="0$< 0$u 7( " (0#$ 0$57"#( 0&m"7" (< (:$ " "7(0#$m " "'7& "7(0#$m '&="#( $ (=" 0"#" (0& "0 #$5@$ =$.L(0(9& " – (0& "0 9" ( 9& & " 9" u "!'%$0" $9 7(9:"#&m "! (0& "0(.Im(#u %7 u 9&0!" $0:"#u< " 0" u %& 9&%"m(< =$! m"7" (< = "#$'& ;u $=$ " ('7;$ &9& -+J & $ $7& (. K&7" $ $ !( "!7('u $mu !"#( "5(%&'()u #$.P&' & $ "5( ":$7"'( 9&;( (9& 5&'0& "< (9& & 5u@ (#u (9 "%0$ 57"0:"5$<7$ ( "%0&m$9(0$ 9&0!" $0:"#$ 5( $ (9& " 7(!m(!u#u.

N$'& (:" 57 #(#u " m( $ 0$ (=" 0$ u (9& u;$ 0u

2.1 APSORPCIONE BAZE

A5 &75:"&0$ =(!$ – 5&' & $ 9$ m& u 57"m" " #. $mu &%( " %&'u "(9& 0(57(%" " $mu !"#u. I!7( u#u $ 9&m="0(:"#&m %& 9&%(< u #( " '7u "m( "< 9(& " '&'( 9&m $mu ( &7( 9" 7('$ %&'()u #$ $mu !"#$. D& ( $9&7" $ !( "!7('u #$9&%" " m( " ( "5& & u=" 0"m "#$9&%"m(. O%$ 5&' & $"m(#u '&=(7 '" 5$7!" $ " "#$5 "! $'< '&=7& $ m(;u – "m(#u '&=(7 (?0" $!( 9&;u. N$'& ( (9 &%" 5&' & ( #$ '( "5(9 m( $ 9(& " m( " "u #"9&%&'":"< (m& $ (9@$ 5"7(#u.

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2.2 SILIKONI

S" "9&0" – u &7 (0 9( #$'"0#$0#( " ":"#um( u 9"m( u ( &m" " ":"#um(%$!(0" 57$9& 9" "9(. S" "9&0" u " 0" 5(7(?0"m( 5& ?!" 9"m " $m"# 9"m& &="0(m( ( 9"m( "m(#u " " (0 %" 9&!" $ . H$m"# 9" u %7 & (=" 0" "%$&m( "'7& &=0" 5( $ 9&7" $ 9(& !(@ " 0" 97$m&%". O 5&70" u 0(&9 "'(:"#u " ?!"& &@9" u "0'" $7$0 0". O' " "9&0( 0(# $@>$ $ 9&7" $" "9&0 9( u #(< 9( $ 5&m&>u & %7@>"%( ( 57$%&'$ u m( ". N$ m"#u $9&7" " " 9(& 5&' & $ !( m( " !( & ".

3. PODLOGE SA VODOM

P&' & $ ( %&'&m " " 97$m&%" $ '(0( 0(#%"@$ 9&7" $< 9(& 5&' & $ !(57"m#$0u #$9&%" " u5 (0:" 0( 9&;u. T& u $mu !"#$ " ( $ $ &' u #(0$ "%&'$0$ (!$< m$9$ u 9&0!" $0:"#$< #$5@$ "! $'( &' &=" 0" m( "< 9&;(" '&=7& 5&'0& "< '&=7& & 5u@ (#u #$9&%" $ u5 (0:$. K(' $ 57"m#$0$ 0(9&;u %&'$0( (!( " 5(7(%( ('$>"< @ & #$ 57"#( 0& !( =& $ 0"9(< #$7m(0#u#$ & #$>(# =& ( " %7(=(. P7" " 5(7(%(0#u 0( 9&;" & (% #(#u u #(0u57$% (9u " " ? m< 9" $ '&=7& '7;" 0( 9&;" " &m& u>(%( '&=(7 9&0 (9 "#$9(( 9&;&m< m(0#$ m( $ " (9& $ 5"7(#u. P&@ & ('7;$ %$ "9u 9& " "0u %&'$$9&0&m" 0$ u< ( " 57" u %& %&'$ 5& &'u#$ 7(!%u m"97&&7 (0"!(m( 5($ m&7(#u 9&0!$7%" ( ". K(& '" 5$7!0" " $m" & #$ #"%" u 0( &5 & u.P&' & $ ( %&'&m " " 97$m&%" '"#$ $ $ u '%"#$ 7u5$< 57$m( &m$ '( " #$m( 0( (!( u0u 7(@0#( " " 5& #(@0#( (!( u $mu !"#" " & 0(1. K7$m&%$ "5( $mu !"#$ %&'()u #$2. K7$m&%$ "5( $mu !"#$ u #$)%&'(

3.1 KREMOVI – Em !"#$% &'()* !$%

K7$m&%" &%& "5( 0(!"%(#u $ $ & " m( 0"m 97$m&%"m( !( & @ & "m #$ 5& #(@0#( (!( m( < '&9 #$ %&'( u0u 7(@0#( (!( " ?0& '" 5$7 &%(0( u

*


10/20

m( 0 (!". K(' $ 57"m#$0$ 0( 9&;u< %&'( " 5(7(%( " ('"< '&9 m( 0((!( & (#$ 0( 9&;" " 57#$ (%( " 5(7(%(0#$ %&'$. Z( & &%" 97$m&%" '#$ u#u "9(& $m& "#$0 0". M&> 5$0$ 7(:"#$ m( 0$ (!$ 57" " 5(7(%(0#u %&'$ !(%" " &'57"7&'$ m( 0$ (!$. Gu=" (9 %&'$ '&%&'" '& 5&%$>(0#( 9&0:$0 7(:"#$ "#$9(0( 9&;"< @ & #$ 9(7(9 $7" " 0& !( &=( "5( 97$m&%(< " & &m$ 7$=( %&'" "7( u0( 57" '&!"7(0#u.P&' & $ &%& "5( 5& &'0$ u !( 57"m#$0u & $& & u=" 0" " "'7& & u=" 0""#$9&%(. O $& & u=" 0" "#$9&%" 0( (!$ $ u 5& #(@0# (!" " &'m( 57"(5 "9(:"#" '& (!$ u 9&0 (9 ( 9&;&m. H"'7& & u=" 0" "#$9&%" u u u0u 7(@0#(!" " 5&7"#$ '& 5"#$%(#u 0( 5&%7@"0u 9&;$< #$7 =7!"0( & 5u@ (0#( (9 "%0"57"0:"5( !(%" " &' & ( u 9 u (!" 7( %&7$0". Z( & #$ =& #$"'7& & u=" 0$ #$9&%" $ u5 (0:$ (% #( " u 97$m&%$ $mu !"#$ "5(u #$)%&'(. N(# $@>" $mu ( &7" & $ $7& < :$ " 0" ( 9& & < (0& "0< (0& "0 9"( 9& & < $ 7" 5& " "'7&9 " 0" ( 9& & ( m( 0"m 9" $ "0(m( 9" u 5&!0( "5&' "m$0&m S5(0 &%". M0& $ #$9&%" $ u5 (0:$ 9(& @ & u um5&7<:"09&9 "'< ;"%"0 (m"'& &7"'< 5$7u =( !(m " '7.< m& u $ 57"m#$0" " ( &%"m5&' & (m(. M$ u "m< &%$ 5&' & $ u "09&m5( "=" 0$ ( #$9&%" "mu5 (0:(m( 9$ '&%&'$ '& 7(!'%(#(0#( $mu !"#$. T& u 57"#$ %$ (m$0 & < $0& < &9( 0" (0$ $ ":"< %&'&0"9 5$7&9 "' " '7.

3.2 KREMOVI – Em !"#$% !$%*&'()

P&' & $ &%& "5( u $mu !"#$ u #$)%&'( " %&'( 57$' (% #( 5& #(@0#u(!u u 9 #$ ?0& '" 5$7 &%(0( m( 0( " " u0u 7(@0#( (!(. P&@ & #$ %&'(5& #(@0#( (!(< &%" $ 97$m&%" 0(!"%(#u #&@ " %&'$0" 97$m&%". M& u $7(!7#$ "%( " ( %&'&m " (9& 5"7( " ( m#$ ( (5 "9(:"#$< 5( $ !=& & ($ & 0(!"%(#u " 5$7"%$ =(!$. U (7m(:"#" 0(#%(;0"#u "7&%"0u &%(9%$5&' & $ "0" $mu ( &7 " &' 0#$ ( !(%" " ?!" 9( (=" 0& $mu !"#$ "9&m5( "=" 0& ( #$9&%" &m u5 (0:&m. Im(#u "#$5 "! $'< (9& $0(0& $ 0( 9&;u " u!&9&;u< 0( % (;0$ $9:$m$ " 7(0":$ $ (9& 0(0& $ #$7

#$ " ( % (;0( (!(< 0$ %(7(#u 0$57"#( (0 & #$>(# m( 0&>$< 0$ !( %(7(#u5&7$ 0( 9&;"< ( 9&' " 5(7(%(0#( %&'$ %(7(#u & #$>(# ( $0#(. V&'$0"97$m&%" 5& &'0" u " !( 57"m#$0u 0( 9& m( $ '"#$ &%$ "#$ (< #$7 $ (9&

1+


11/20

5"7(#u. N(0"#$ " 0( 9&;u 5& "#$ " 5(7(%(0#( %&'$ & (% #(#u 0$%"' #"%um( 0u 57$% (9u " " ? m< 5( $ m& u 9&7" " " " '(0#u. D&=7& $ 5&'0& $.H"'7& & u=" 0$ #$9&%" $ u5 (0:$ & 5u@ (#u =7!& " 5& 5u0&. P&' & $ &%&"5( ('7;$ !0( 0u 9& " "0u %&'$ " '& 8+J< @ & " "0" %7 & $9&0&m" 0"m5&' & (m(. A " 57" u %& &%(9& %$ "9$ 9& " "0$ %&'$ #$ " 0#" &% 0$'& ( (9<

#$7 (9& u=$ %&'u " u@$ $. Z( & $ m&7(#u 5(9&%( " " u%( " u '&=7&!( %&7$0"m u'&%"m(< 0(#=& #$ u u=(m(. Z=& 57" u %( %&'$ 0(5('(#u "m"97&&7 (0"!m" 5( $ m&7(#u 9&0!$7%" ( ". Z( m( 0u (!u &%" 97$m&%(u5& 7$= #(%(#u $ $ 0" " %7 " 5(7(?0< %(!$ "0< =" #0( u #(< "'7"7(0( u #(<& $" & $( < :$ " " $(7" ( 9& & " '7. V&'$0( (!( ('7;" $ & 5&7$'"'7& & u=" 0" $mu ( &7( " 7(!0( "'7& 9&50( 7$' %(< 9( $ '&'(#u '(57"#$ $ " " =(7 u 5&7$ u=" (9 %&'$< 057. 57&5" $0 "9& < ":$7& < &7=" & "'7. Z( $mu !"#$ "5( u #$)%&'( u %7 $0& #$ '( 5& (#u (=" 0"#$< (9& $ !(0#" &%u "!7('u u5& 7"#$=$ 9&m="0&%(0& "'7& & u=" 0" " "5& & u=" 0"$mu ( &7". T(9%$ m#$@(%"0$ 0(!"%(#u $ (m& $mu u#u>"m %& 9&%"m(.O0" ('7;$ *+J "5& & u=" 0" " 1+J "'7& & u=" 0" $mu ( &7(.L"5& & u=" 0" $mu ( &7" 7('$ $mu !"#$ "5( %&'()u #$< ( "'7& & u=" 0"<$mu !"#$ "5( u #$)%&'(< m$ u "m 9&m="0&%(0" '(#u 9&m5 $9 0$$mu ( &7$ 9" 7('$ %7 & (=" 0$ $mu !"#$.

STEARATSKI KREMOVI S $(7( 9" 97$m&%" "m(#u %7 & #$'0& (%(0 ( (%. T& u $mu !"#$ "5(u #$)%&'( " ('7;$ 1- 3+J m( 0$ (!$ 9( "m( ( 9u &5 #$0#( '( $9&"!0(' 3 C< u57& 0& '7u "m 5&' & (m(. N(#%$>" '"& m( 0$ (!$ ( " $"! $(7"0 9$ 9" $ "0$ &' 9$ #$ (5u0"?9&%(0& (m& 1+ 2-J< ( & ( (9 $0( (!" 9(& &=&'0( 9" $ "0(. Z( (5u0"?9(:"#u $(7"0 9$ 9" $ "0$9&7" $ $ 9(7=&0( " " " "'7&9 "'" 9( "#um( " 0( 7"#um(< !( "m =&7(9 " u0&%"#$ %7"#$m$ 0(7& " & m0& & 7(!0" (m"0"< 0(#%"@$ 7"$ (0& (m"0. I!=&77$' %( !( (5u0"?9(:"#u #$ %(;(0< #$7 &' & ( !(%" $ " & &="0$ '&="#$0&97$m(. K( "#um "'7&9 "' '(#$ m$9@$< ( 0( 7"#um "'7&9 "' %7@>$ $(7( $.B&7(9 '(#$ 97$m&%$ "#$5$< ="#$ $ =$< ( " &%" 97$m&%" %7$m$0&m 5& (#u!70( ". T7"$ (0& (m"0 '(#$ '&=7$ 97$m&%$< 5& &'0$ 9&0!" $0:"#" " m( $( 9( 0& " 5( $ !( & 0(#%"@$ " 57$5&7u u#$. S $(7( 9" 97$m&%" 7$'&%0&

11


12/20


13/20

+.1 POLIETILENGLIKOLI

P& "$ " $0 "9& " – u 9&0'$0!(:"&0" 5& "m$7" $ " $0&9 "'(.

P& "$ " $0 "9& " 57"m#$0#$0" 0( 9&;u u 0$ &9 " 0"< 0$ 57#$ (%(#u "!m#$0u&5 & $ " ( &%(. N( 9&;" 7(!%"#(#u "!7(!" & & m& 9& '#$ &%(0#$ " &'u!"m(#u%&'u 9(9& 9&;"< (9& " 7(0(m( " $'$m"m(. P&' & $ &%& "5( m& u $m(!( " 0( % (;0u 9&;u< '#$ $ '&=7& !('7;(%(#u. S (=" 0$ u " 0$ 0(5('(#u" m"97&&7 (0"!m". M& u $ 9(& 5&' & $ 57"m"#$0" " " 0( u5( #$0u " % (;0u9&;u< 7(0$< 0(7& " & $ 57$5&7u u#u !( 9& m( $ '"#$ &%$. P& "$ " $0"9& 9$ 5&' & $ m& u $ 9&7" " " !( %$ "9" =7 "#$9&%(< ( " #$ " & (9&

u %7 $0& '( u "09&m5( "=" 0$ ( %$ "9"m =7$m #$9&%" " u5 (0:".I09&m5( "=" 0" u 057. ( $0& "m(< 0$9"m (0 "="& ":"m(< #&'&m " #&'"'"m(<(0"0 9"m 9" $ "0(m(< & "m( ;"%$< 7$=7( " ="!mu ( " '7. R$( u#u ( 0$9"m5 ( " 0"m m( $7"#(m(& $mu 7$=( %&'" " 7( u0( 9&' 5(9&%(0#(. N$ m"#u$ u5& 7$= #(%( " 9(& 5&' & ( !( & 0$ m( ".

+.2 ORGANSKI GELOVI

G$ " u 5& u %7 " " $m" u 9"m( #$ 97$ (0#$ '" 5$7!0& 7$' %( " "5& #(@0#( (!( & 7(0" $0& m7$;( &m 7u9 u7&m 9u %(7( '" 5$7!0( " "u0u 7(@0#( (!(. U9 (5(0#$m 5& #(@0#$ (!$ u m7$;( u 7u9 u7uu0u 7(@0#$ (!$ 5&%$>(%( $ %" 9&!" $ " " $m 5& (#$ 5& u %7 .P& u %7 ( 9&0!" $0:"#( $ ( &m& u>(%( 0#" &%u 57"m#$0u 9(& 5&' & (.K&0!" $0:"#( $ ( #$ (9%( '( 0$ 5&' "#$;u 0"9(9%&m %(7"7(0#u

57&m#$0&m $m5$7( u7$ " m& u $ (9& " " 9"%( " "! u=$ " m(!( " " 0(0" 9"m $m5$7( u7(m(. G$ " u 9&m5( "=" 0" ( $ $9 7& " "m(< 9" $ "0(m( "=(!(m(. O%$ 5&' & $ (9& & 5u@ (#u "#$9< 5$7u $ ( %&'&m< 5( u5& &'0$ " !( 57"m#$0u 0( 9& m( $ '"#$ &%$ "#$ (. K('( $ 0(0$ u 0( 9&;u& (% #(#u 57" " 5(7(%(0#u %&'$< 9( ('"< ? m " " 57$% (9u 9( #$0$%"' #"%(< 5( u $ 5&' & $ 5& &'0$ " !( 7$ "7(0#$ & %&7$0" 5&%7@"0("#$ (. " m 9" !(& (#$ 0( 9&;" 5&0&%0"m 9&0 (9 &m ( %&'&m=7!& =u=7" "

" 5"7( $. P& &'0" u " !( "!7('u 0$9" m( " !( & ". Z( "!7('u 5&' & ( (&7 (0 9"m $ &%"m( 9&7" " $ @97&=< ;$ ( "0(< ( "0( " " '$7"%( " :$ u &!$< (

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'( =" $ 57"#$ "& u=" (9 %&'$ "! &%(9%" 5&' & ( '&'(#u $ "'7& 9&50(7$' %( 057. ":$7& < &7=" & < 5& "$ " $0 "9& " " '7.

+.3 NEORGANSKI GELOVI

P&' & $ &%& "5( u " 0$ 5& & &="0(m( 5&' & (m( &7 (0 9"$ &%(. I &%$ 5&' & $ ('7;$ %$ "9u 9& " "0u %&'$ 5( "m $ m&7(#u '&'(%( "% (;$>( 7$' %( 057. ":$7& . M&7(#u $ 5(9&%( " u '&=7& !( %&7$0$5& u'$ '( $ 57"#$ " u=" (9 %&'$. Z( "!7('u 0$&7 (0 9" $ &%( !(#$9&%" $ m( " 9&7" $ $ =$0 &0" < V$$ um " A$7& " . A$7& " & "m (

%&'&m 7('" $ &%$ " ( ( 9& & &m " ":$7& &m< u #"m( " '.

,. IZBOR PODLOGA ZA LJEKOVITE MASTI

P7" "!=&7u 5&' & $ !( #$9&%" $ m( " m&7(#u $ u!$ " u &=!"7 m0& "(9 &7"< 57"#$ %$ ( (0#$ 9&;$ " &=& #$0#$ 9&;$< m#$ & (5 "9(:"#$ "#$9(<57"7&'( #$9&%" $ u5 (0:$ 9( $ 57"m#$0#u#$ u &= "9u m( "< !( "m m&7($ %&'" " 7( u0( " & $ 0& &@9&m 5& u59u< & (=" 0& " "#$9( u &'(=7(05&' &!" 9(& " & ;$ #$0&m '$# %u. O 0&%0& 57" "!=&7u 5&' & ( #$ & '( "#$90$ m"#$ '( =u'$ "09&m5( "=" (0 ( 5&' & &m< '( 0$ '7(;" 9&;u " '( #$(=" 0(< ( 0(#%(;0"#$ @ & $ 7(;" &' #$'0$ 5&' & $ #$ '( (9& & 5u@ (#$9&%" u u5 (0:u. I!=&7 5&' & ( $ $ & %$!u#$ " !( 5" (0#$ 7$ &75:"#$"#$9( 97&! 9&;u. T7$=( " (>" '( #$ 7$ &75:"#( "#$9( 97&! 9&;u 7"#$ 9&5&;$ #0( u '$7m& $7(5"#". P&' 7$ &75:"#&m $ 5&'7(!um"#$%( 57& (! "#$9(97&! 9&;u '( =" $ 5& " & " $m( 9& '#$ &%(0#$. P7" "!=&7u 5&' & ( 7$=("m( " u %"'u '( u !( 57"m#$0u m( " 0( u!&9&;u< 7(0$ " &! "#$ $0u 9&;u5& &'0"#$ 5&' & $ ( %&'&m " & "5( $mu !"#( u #$)%&'(. P&@ & #$ %&'(5& #(@0#( (!( (9& $ !('7;(%( 0( % (;0"m 5&%7@"0(m(. Z( " $ %7 $5& &'0$ u " 5&' & $ &7 (0 9" $ &%(< 9" u u! & 5& &'0"#" " !( m( 0u "& #$ #"%u 9&;u.

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-.3 MASTI TIPA EMULZIJA

M( " "5( $mu !"#( – 7('$ $ &5 #$0#$m. T&5 #$0#$ 57" "!7('" &%" m( "%7@" $ (9& @ & $ " &5$ !(#$'0& %$ 9&m5&0$0 $ 9$ $ &5$ 0( %"@$m5$7( u7"< ( 5& $=0& 9&m5&0$0 $ 9$ $ &5$ 0( 0"; $m5$7( u7".M$ u "m< &%(# 0( "0 $ "!=#$ (%( !=& %(7(0#( $u $ " 9" m#$ (< 5( $m( " " $mu !"#$ 7('$ (9& @ & $ 5&m"#$@(#u !(#$'0& %$ "5& & u=" 0$9&m5&0$0 $< ( 5& $=0& "'7& & u=" 0$< 5( $ " #$'0$ " '7u $ !( 7"#u 0(+ C. Z( "m $ %&'$0( (!( '&'(#$ m( 0 (!" u! ( 0& m"#$@(0#$ '&5& 5u0& ( $0#(.

U (5& $:" m( " $ 7('$ u 5( $0" ( " &0( m&7( =" " "!7( $0( &'0$ 7 (#u>$ $ "9(. D( =" #$'0( #$9&%" ( m( =" ( '&=7& 0(57(% #$0( m&7($ '&=7& &m& $0"!"7( ". Z( &m& $0"!"7(0#$ m( " 9&7" $ $ m#$@( ":$ "m "0&%" ( %( #:"m(. M "0 ( 7" %( #9( " u " 0#(%( #$9&%" u u5 (0:u " '&=7&&m& $0"!"7( #$9&%" u m( . U " 0#(%(0#$< 7"#(0#$< ( $0#$< m"#$@(0#$<&m& $0"!"7(0#$ " 5(9&%(0#$ u &5$7(:"#$ 9$ $ 9&7" $ 9&' "!7('$ m( "<9(9& u "0'u 7"#"< (9& " u 57&"!%&'0#" 0( m( & u (5& $:".N(#=& #" 0( "0 5(9&%(0#( #$9&%" " m( " #$ 5(9&%(0#$ u u=$< u 9"m( #$m( !(@ ">$0( &' %" 5& #(@0#" (9 &7(< 9%(7$0#(< ( 57"m#$0( m( " "!u=( #$ " "#$0 9( " 5& &'0( !( '&!"7(0#$. N$9$ $ #$9&%" $ m( " m&7(#u7('" " $7" 0&< & $ "!7" " & 7(;" 9&' m( " !( 7(0$ " m( " !( & ".

. ISPITIVANJE LJEKOVITIH MASTI

I 5" "%(0#( #$9&%" " m( " m& u =" " 7(!0&%7 0(< ( " !( 57&:#$0u0#" &%& 9%( " $ ( " $5$0( " &>$ %$&m( u %(;0( " 5" "%(0#( 57&:$0 ((9 "%0& 57"0:"5(< $7" 0& "< " 5" "%(0#$ 5& &=0& " 57"m(0#( %&'$< "5($mu !"#$ 9&' $mu !"&0" 5&' & (< 9&0!" $0:"#$< (=" 0& " " 5& &=0& "& 5u@ (0#( (9 "%0& 57"0:"5( 9(& " $5$0( '" 5$7!" $ (.

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S5& &=0& 5&' & $ " #$9&%" $ m( " '( 57"m" %&'u "!7(;(%( $%&'$0"m =7$m. V&'$0" =7 #$ =7 9" 9(!u#$ 9& "9& 7(m( %&'$ m&;$ '(57"m" 1++ m( " " '( #$ 7(#0& !('7;".

O'7$ "%(0#$ $5$0( '" 5$7!" $ ( %7@" $ (9& @ & $ "!%#$ 0( 9& " "0( m( "7(!m(;$ u (09&m u 5&m&>u @5( u $ 0( m"97& 9&5 9& (9 & "5& m( 7( 5&' m"97& 9&5&m. N( &%(# 0( "0 m&;$m& m"97&m$ 7&m m#$7" "%$ " "0u $ ":(.

I 5" "%(0#$ (=" 0& " 5&' & ( " #$9&%" " m( " %$&m( #$ %(;0( !(57&"!%& ( (. P7&"!%& ( u%"#$9 ;$ " '( mu 57&"!%&' & (0$ @ & 'u;$(=" (0. M$ u "m< $@9& #$ 0&7m"7( " %7"#$m$ u&5@ $0& !( 7(#0& 5&' & (

" #$9&%" " m( ". T& %7"#$m$ $ m&7( $9 5$7"m$0 ( 0& &'7$'" " !( %(9"57$5(7( . P7" " 5" "%(0#u (=" 0& " m&7( $ u %7'" " (=" 0& 9(9& 5&' & $(9& " (9 "%0& 57"0:"5(.

I 5" "%(0#$ (=" 0& " &=u %( ( " 5" "%(0#$ ?!" 9$ " $m"# 9$(=" 0& ". I 5" "%(0#$ ?!" 9$ (=" 0& " &'0& " $ u (%0&m 0( " 5" "%(0#$

'( " u &9u u%(0#( " 7(0 5&7 ( 0$ '& (!" '& 7(!'%(#(0#( (!(. I 5" "%(0#$$m"# 9$ (=" 0& " 7$=( '( '( &' &%&7< '( " $ 5&' & ( " " 0$9( 0#$0(9&m5&0$0 ( m"#$0#(#u &9&m u%(0#(. K&' m( " $ #&@ " 5" u#$ " $m"# 9((=" 0& (9 "%0& 57"0:"5(.

I 5" "%(0#$ 9&0!" $0:"#$ 5&' & ( " " m( " %$&m( #$ %(;0&. M( " 0$m"#u =" " 57$%"@$ %7 $< #$7 $ $@9& m(;u " %('$ "! u=$ " " $ $. Z(%7"#$m$ u%(0#( " " 7(0 5&7 ( m( " m& u =" " "! &;$0$ !0( 0&m %(7"7(0#u$m5$7( u7$. M( " 9$ 0$m(#u 5& &'0u 9&0!" $0:"#u 0( 0";"m$m5$7( u7(m( #(9& & %7 0u. O=7( 0& 0( %"@"m $m5$7( u7(m( 5& (#um$9$ @ & 9&' u 5$0!"&0" m( " 0"#$ 5&;$ #0&< #$7 m&;$ '&%$ " '&( &;$0#( (9 "%0" 57"0:"5(. U 5& $'u 9&0!" $0:"#$ 0(#5&;$ #0"#$ u &0$5&' & $ 9$ >$ "m( " m$9u 9&0!" $0:"#u u @"7&9&m $m5$7( u70&m5&'7u #u.

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O'7$ "%(0#$ 9&0!" $0:"#$ "!%&'" $ 5&m&>u 5$0$ 7&m$ 7( " "7& (:"&0& %" 9&!"m$ 7( 9(& " 5&m&>u 5$:"#( 0" 9&0!" &m$ (7(.

I 5" "%(0#$ $mu !"&0" m( " %7@" $ 0( $5$0u $mu "7(0#(< "5$mu !"#$ " $5$0( '" 5$7!" $ ( u0u 7(@0#$ (!$.K%( " ( "%0( " 5" "%(0#( m( " &=u %( (#u "'$0 " $ 0$ 7$(9:"#$< !( "m" 5" "%(0#$ 57" u %( " 9& " "0$ (9 "%0& 57":"5( " " 0$9$ &' 9&m5&0$0 " um( ".

L#$9&%" $ m( "< !( 9$ #$ 57&5" (0& '( $ 57"57$m(#u $7" 0&<m&7(#u $ " 5" "%( " " 0( $7" 0& . T& " 5" "%(0#$ 7$=( "!%&'" " 5& "#$ "!7('$9(& " u &'7$ $0"m %7$m$0 9"m "0 $7%( "m(.

I 5" "%(0#$ 5& &=0& " & 5u@ (0#( #$9&%" " u5 (0:" "! m( " m&;$$ &'7$ "%( " "0 %"%& " "0 %" 7&. I0 %"%& " 5" "%(0#( $ %7@$ 5&m&>u =( "m(79"7(0" u5 (0:". D( $9& $ %"@$ " 5" u#$ "0 %" 7&. O%& " 5" "%(0#$ $m&;$ "!%$ " #$'0& (%0"m m#$7$0#$m '" u!"#$ #$9&%" $ u5 (0:$ "!5&' & $ u 0$9" 5& &'(0 u5 7( 9" !(m"#$0#u#$ 9&;u. T( $ m$ &'(( " u &m$ '( $ #$9&%" ( m( (%" 0( ( (7 5 & u< 0( 9 u !( "#(0$=(9 $7"#$ & #$ #"%$ 0( "#$9 9" $ " 5" u#$ " m#$7" "0 "=":"&0( !&0(. O%(9& $m&;$ " 5" "%( " & 5u@ (0#$ "#$9&%( 9" "m(#u (0 " $5 " 0( % %(. K&''7u " "#$9&%( m&;$ $ " 5" "%( " " 5&m&>u "0'"9( &7( 9" >$ $ &=" " "5&9(!( " '( " #$ 5&' & ( & 5u " ( "#$9.

L#$9&%" $ m( " $ u%(#u 0( ('0&m m#$ u< !(@ ">$0&m &' %#$ & " "% ( $.

8. LITERATURA

L#$9&%" $ m( " – '7. %$ . m$'. ,$ $0( u7(0

P7. '7. :. D. S(9(7 P7& . '7. :. . B&;">

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OBLIKOVAN,E LI,EKOVA – PRAKTIKUM< M. B$>"7$%"> L(>(0 " M. ,u < Z( 7$= 2++

Za a!anja mentora"

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