Max Planck Institute for Metabolism Research

8th December 2017Venue: Max Planck Institute for Biology of Ageing Joseph-Stelzmann-Straße 9b, Cologne

Participation is free of charge. We are looking forward to welcoming you.

Graduating Class of 2014

GRADUATE SYMPOSIUM 2017

Mitochondria & ProteostasisGulzar Wani (Bergami Lab) Role of mitochondrial peptidase YME1L and OMA1in hippocampal neural stem and progenitor cells in the adult mouse brainHans-Georg Sprenger (Langer Lab) Loss of i-AAA proteaseYME1L leads to progressive axonal degeneration and locomotor impairment in mice Seda Koyuncu (Vilchez Lab) The E3 ubiquitin ligase UBR5 maintains proteostasis of huntingtin in immortal pluripotent stem cellsTania Medeiros (Graef Lab) Autophagy maintains mitochondrial DNA duringlong-term starvation

David Tollervey (Edinburgh, U.K.) Splicing-associated pausing of RNA polymerase II is enforced by ubiquitination of the catalytic subunit

12:30 p.m.

1:50 p.m.

9:00 a.m.

10:40 a.m.

MetabolismAnna Vesting (Wunderlich Lab) The role of NIK in obesity-associated HCC developmentRobert Sehlke (Beyer Lab) Dissecting the tissue-speci�c Drosophila insulin responseNils Hansmeier (Kornfeld Lab) Decoding the impact of obesity long noncoding RNAson liver energy homeostasisKira Allmeroth (Denzel Lab) A sweet friend - mannose is a novel regulatorof stem cell quiescence

Hayley Nicholls (Boston, U.S.A.) The regulation of adaptivethermogenesis and nutrient metabolism by gut microbes

3:15 p.m.

4:35 p.m.

Ageing & LongevityWilliam Bradshaw (Valenzano Lab) Characterising antibody immunity and ageing in a short-lived vertebrate modelMarkus Doll (Schumacher Lab) Role of microRNAs in the regulation of DNAdamage-induced germ cell apoptosis in C. elegansIsabelle Schi�er (Antebi Lab) Conserved muscle microRNA, mir-1, regulates C. elegans proteostasisJabiz Na�si (Niessen Lab) Polarity signalling in the regulation of spindle orientation

Marina Mapelli (Milan, Italy) Molecular mechanisms of asymmetric cell divisions