medi9 pp presentation feb 15
TRANSCRIPT
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An alcohol free complete sanitisation system
A Complete Sanitisation System
Medi9 is a complete sanitisation solution
It kills 99.9% of all known germs, spores, viruses and bacteria and yet it is:
What is Medi9 ?
ALCOHOL FREE TRICLOSAN FREE CHLORINE FREE
NON TOXIC NON HAZARDOUS FOOD SAFE
And is available in an incredible portfolio of application methods (all with the same remarkable performance)ranging from:
DEVICE WIPES SURFACE SPRAYS & WIPES
HAND FOAMS & WIPES
to FOGGING SOLUTIONS & MACHINES TO PROVIDE HIGH LEVEL DISINFECTION OF ALL AREAS
LEAVES NO RESIDUE FRAGRANCE FREE
• IT IS WIDELY ACCEPTED THAT ALCOHOL IS NOT EFFECTIVE AGAINSTNOROVIRUS & Clostridium difficile
and in fact in many instances it actually exacerbates the problem !
• ALCOHOL IS OFTEN INEFFECTIVE AGAINST BACTERIAalcohol-based hand sanitisers claim to kill 99.999% of bacteria, yet laboratory tests have difficulty reproducing these results. According toDr. George Lukasik of Biological Consulting Services in Florida, one of the problems is that without agitation, alcohol only kills the top layerof bacteria and the dead cells then form a protective layers that keep the alcohol from killing the harmful bacteria underneath.
• HIGHLY FLAMMABLE & UNACCEPTABLE TO SOME CULTURESalcohol-based hand sanitisers have been banned from many public areas and school districts in the country, as they pose a significantdanger to children who might accidentally or intentionally ingest the product. To put things in perspective: light beer is “6 Proof”, wine is“24 proof”, vodka is “80 Proof” - a number of alcohol based products are “125 Proof”!
The risk of alcohol poisoning is quite real and it is a danger to small children.
In addition to this many religions and cultures are not comfortable with dealing with alcohol.
Why alcohol free ?
The range: sanitised surfaces
Spray & Foam Large Wipes Small Wipes Tough Wipes
Mini Wipes Bulk Wipes Bulk Solution Pocket Spray
The range: sanitised surfaces
Medi9 is safe to use and effective on all kindsof surfaces - as shown by testing completed byBoeing for cleaning interiors of commercialtransport aircraft.
The range: sanitised personal
Wipes
Hand Foam
Manual & Automatic Dispensers
Mini Hand Foam
Pocket Spray
Personal Hygiene Pack
The range: sanitised personal
Medi9 and the dispensers are popular as they are safe for all touse - even children and vulnerable persons.
Medi9 is dispensed as a foam to increase efficiencies in use anduser acceptance. Available for manual and auto dispensing.
Gel traditionally dispenses at 1.2ml per dose and often requiresusers to apply more than one dose to obtain sufficientquantities and contact times, with a proportion of the geldepositing on the floor.
Medi9 foam dispense at 0.75ml per dose and due to thefoaming process just 1 application is sufficient. Being alcoholfree means it doesn’t dry as quickly thereby lasting the requiredcontact time for it to be effective.
The range: sanitised spaces
Handheld Foggerwill take around 90 seconds to
sanitise a room of approx. 50m²
Room Sanitiserdesigned to run for a longer
period of time when the room is not in use
Mobile Sanitiserwill take around 6 - 8 minutes to sanitise a room of approx.
200m²
The range: sanitised spaces
Whilst decontamination is taking place there is no need to remove equipment, furniture or soft furnishings asMedi9 is chlorine and alcohol free and is safe to use in all environs
The amount of Medi9 atomised into the atmosphere has been carefully calibrated to ensure that thefreestanding items, equipment and the fabric of the building will not be damaged through excessive moisturelevels.
It is not necessary to seal the room or to disable the fire alarm or ventilation system.
Minimum PPE is required as Medi9 does not contain dangerous chemicals that would effect the respiratorysystem – in fact many of Medi9‘s ingredients are found in common cosmetics, body sprays, pharmaceuticalsand medicines.
The area is safe for access very shortly after decontamination has taken place.
What actually is Medi9 ?
Medi9 is a new biocide technology. It combines conventional biocides with a polymer backbone to produce ahighly effective, food safe, non toxic, non tainting product that can be used to sanitise both skin and surfaces inany environment.
It can also be used to clean and sanitise machinery and is highly effective in clinical and non-clinicalenvironments.
Medi9 is suitable as a one stage cleaner and disinfectant or as a two stage cleaning and sanitising process.
How does Medi9 work ?
Medi9 is not a biocidal chemical. It is a biocide technology. It could be said that the whole is greater than thesum of its parts. This is due to the synergy between the polymer and the biocides attached to it. The polymereffectively coats the surface it is applied to and spreads. It not only coats the surfaces in need of cleaning butalso anything that is adhered to it - including the microorganisms.
Bacteria, when left to colonise a surface, forms what is known as a biofilm. Medi9 coats this biofilm and stopsreproduction in the colony. As the colony becomes older it becomes more susceptible to biocides and at thispoint the biocide in Medi9 can enter the cell and destroy it. This cationic technology coats the surface of abacteria or a virus molecule and de-natures the proteins involved.
This mode of action means that Medi9 is also effective against spores. By coating the bacteria in its spore stateit stops the spore from germinating and then changing from an endospore to a vegetative cell.
Medi9 has a cumulative and residual effect. The polymer coating leaves a monomolecular layer that will workfor a time after the initial application; it also combats re-deposition of soil and the formation of biofilms. Thismeans that over time the incidences of re-infection will reduce.
The cationics in the Medi9 formulation act as corrosion inhibitors, this is especially the case for the longer alkylchain length cationics in Medi9 such as DDAC and Benzalkonium chloride. The cationics are positively chargedand hence are attracted to the surfaces in solution, as most surfaces are negatively charged when in an aqueousenvironment. This thin layer of cationic protects the metals from corrosion to some extent.
Residual Protection & Reduced Corrosion
Why is Medi9 different ?
For biocides to work effectively against microorganisms, they must be found in a product above a level knownas the Minimum Inhibitory Concentration (MIC). For example: the MIC of Sodium Hypochlorite (bleach) isaround 2500mg/L. The polymer technology used in Medi9 means that the biocides in the product mixture canbe at concentrations below their individual MIC yet still produce an effective biocidal product.
Many biocides when used on their own are extremely toxic to humans and there are many health and safetyissues to consider, especially when dealing with the higher-end disinfectants. Medi9 is classified as NonHazardous due to the relatively low amounts of these biocides. Medi9 is, therefore, a safer product.
Medi9 v Hypochlorite BleachHypochlorite bleach typically used would be diluted to achieve an in-use concentration of 0.1% or 1000ppm.For hypochlorite to be stable it has to maintained at a reasonably high pH - typically 11.5 - 12.5. The dilution to1000 ppm sacrifices the bleach stability in two ways:
1 - By lowering the pH, chlorine bleaching / gas generation is possible: this reduces the strength of the solution.
2 - Metal ions in the water, especially iron, will greatly accelerate the decomposition of chlorine bleach byacting as a catalyst.
Contamination of the 1000ppm solution of various kinds is expected from cleaning rags and even the waterthat is used to dilute the bleach. Soils - especially protein soils - will react with bleach, decomposing it andreducing its concentration.
Sunlight and heat will significantly increase the rate of decomposition of a bleach solution.
Medi9 is not diluted and there is no de-composition that takes place, thus the activity of the product can be assured. Bleach, on the other hand, has a short shelf life and needs to be replaced frequently to ensure that the concentration of available chlorine is maintained at an effective level.
The action of chlorine bleach on the skin frequently causes rashes and soreness even at high dilutions.
So what are the active ingredients ?
Didecyldimonium Chloride
Lauralkonium Chloride
Polyaminopropyl Biguanide
Didecyldimonium Chloride
An antiseptic/disinfectant that is used in many biocidal applications. Causes disruption of intermolecularinteractions and dissociation of lipid bilayers. A broad spectrum bactericidal and fungicidal, it is used as adisinfectant cleaner for linen. Recommended for use in hospitals, hotels and industrial applications. Also usedin gynaecology, surgery, ophthalmology, paediatrics, OT, surface disinfection and for the sterilisation of surgicalinstruments and endoscopes.
Quote from STEPAN: The cornerstone of STEPAN’s biocide technology is Quaternary chemistry.
More specifically, STEPAN features an extensive array of alkyldimethylbenzylammonium chloride (ADBAC) and didecyldimethylammonium chloride (DDAC) compounds. The alkyl chain distribution can be modified to achieve a wide range of biocidal performance characteristics.
Building on our quaternary chemistry capability, we can also utilise non-biocidal compounds to further improve the biocidal efficiency of quaternary compounds in frame formulations. The unique combinations of quaternary biocides and non-biocide compounds designed to achieve superior results is
referred to as ‘BTQ’ (“Beyond The Quat”) programme.
Lauralkonium Chloride
From the Benzalkonium Chloride family - a cationic surface-acting agent belonging to the quaternaryammonium group. It has three main categories of use: as a biocide, a cationic surfactant and as a phasetransfer agent in the chemical industry.
Polyaminopropyl Biguanide
A disinfectant and a preservative used for disinfection on skin and in cleaning solutions. It is also an ingredientin many deodorant bodysprays. It is a polymer or oligomer where biguanide functional groups are connected byhexyl hydrocarbon chains with varying chain lengths. PAPB is specifically bactericidal at very low concentrations(10 mg/l) and is also fungicidal.
It has a unique method of action: the polymer strands are incorporated into the bacterial cell membrane,disrupting the membrane and reducing its permeability - this has a lethal effect on bacteria. It is also known tobind to bacterial DNA, alter its transcription and cause lethal DNA damage. It has very low toxicity to higherorganisms such as human cells – these have more complex and more protective membranes.
What does Medi9 break down into ?
Amongst other ingredients, Medi9 contains cationics: these are electrically charged molecules that causeMedi9 to be attracted to negatively charged surfaces. These help to provide residual protection. However,Medi9 is readily biodegradable and over time the larger, more complex molecules will break down intosmaller molecules such as esters, amines and carboxylic acids. Regular applications of Medi9 will result in theaqua present in the solution removing previously applied molecules. A plateau is then reached where there isan equilibrium between the applications of Medi9 and its removal. The raw materials are not classified as toxicso there is no risk of toxicity increasing through regular use.
Medi9 works as a catalyst and will increase the breakdown of HPV in a similar way to Sebum and Lanolin - itdoes not result in increased toxicity or produce any harmful substances.
What is Medi9 effective against ?
Medi9 has also been tested for virucidal activity. This test involved applying Medi9 to a surface onto which aknown number of viral phages had been inoculated. This simulated the cleaning of a surface with, for example,a wipe.
These tests assessed Medi9 against a number of bacterial and fungal strains to see if the product had thebroad-spectrum antibacterial capability that is needed for a disinfectant/sanitiser in modern health care andfood production areas. However, these tests are not exhaustive and we will be constantly testing Medi9 againstother bacterial strains to give concrete proof to our claims.
What is Medi9 effective against ?
Medi9 has been tested to a number of European Standards:
EN1276 Quantitative suspension test for the evaluation of bactericidal activity of chemical disinfectants.
EN13704 Quantitative suspension test for the evaluation of sporicidal activity of chemical disinfectants.
EN1650 Quantitative suspension test for the evaluation of fungicidal activity of chemical disinfectants.
EN14476 Quantitative suspension test for the evaluation of virucidal activity of chemical disinfectants.
EN14476 Quantitative suspension test for the evaluation of effectiveness against Ebola surrogate virus
EN14563 Quantitative carrier test for the evaluation of mycobactericidal or tuberculocidal activity ofchemical disinfectants used for instruments in the medical area.
EN1500 Hygienic Hand Rub Standard Test
ISO22196 Residual Surface Activity
Medi9 has been tested against - Bacteria
Medi9 has been tested against - Bacteria
Testing to EN1276 showed a log reduction
greater than 5 in under 1 minute
in dirty conditions.
Medi9 has been tested against - Spores
Medi9 has been tested against - Spores
The test according to EN13704 showed a log
reduction greater than 3 in under 1 minute in dirty
conditions, upon further analysis if the sporicidal
test suspension was greater then the log
reduction would equate to 6.447
Medi9 has been tested against - Fungi
Medi9 has been tested against - Fungi
Tested to EN1650 and showed a log
reduction of 4 in under 1 minute
in dirty conditions.
Medi9 has been tested against - Viruses
• Ebola
Medi9 has been tested against - Viruses
Tested to EN14476, the Norovirus test was carried out on the surrogate Feline Calcivirus and showed a log
reduction of 4 in under 5 minutes with a 5% soil load
replicating dirty conditions. It would therefore suggest that a higher log reduction would be achieved if conducted in
low soiling or clean conditions.
Potential applications
Medi9 can be used in many different areas. With its broad spectrum of antibacterial properties, it provides ananswer to the many infection control questions that customers and infection control specialists interested incleansing and sanitising their products and workspace may have.
Areas include:
Kitchens Restaurants Consulting Rooms
Stairways Lifts Storage Areas
Communal Areas Corridors Bathrooms
Washrooms Changing Rooms Gyms
Inside Areas Outside Areas Around Swimming Pools
Ballrooms Shops Laundry Areas
For personal hygiene Wards Theatres
Thank you
Thank you for taking the time to view our presentation.
We look forward to working with you soon.
