medical study centre session 2011-2016
TRANSCRIPT
![Page 1: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/1.jpg)
Medical StudyCentre
Session 2011-2016We the team of medical study centre session
2011-2016 have copmiled these pharmamnemonics unit wise. We hope our effort of
mnemonics collection will help you all in proff.
We want that this collection must be shared withyour friends and fellows .please give us your feedback about this collection in our group and page
Regards: admin Panel
ALI Zeeshan(QAMC)
ATHAR ALI (QAMC)Noreen FATIMA (FJMC)
https://www.facebook.com/groups/Medical.study.centre/
http://atharali187.blogspot.com/Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 2: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/2.jpg)
PharmacologyMnemonics
General pharma
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 3: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/3.jpg)
1. Zero order kinetics drugs in high doses
APE
Aspirin
Phenytoin
Ethanol
2. P450 inhibitors
IQ SMACKD
Isoniazid
Quinolones
Spironolactone
Macrolides
Amiodarone
Cimetidine
Ketoconazole
Dapsone
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 4: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/4.jpg)
3. P450 inducers
GTQ CRABS
Grisofulvin
Tetracyclin
Quinidine
Carbamazepine
Rifampin
Alcohol
Barbiturates
Sulfa drugs
4. Enzymes Inhibitors
"Vit. K Cannot Cause Enzyme Inhibition"
Valproate
Ketaconazole
Cimetidine
Ciprofloxacin
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 5: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/5.jpg)
Erythromycin
INH
5. ototoxicity causative agents
A+.B.C.D. "
Aminoglycosides* (Profound and irreverible hair cell loss)
Barbiturates
Cytotoxic drugs-Nitrogen mustard & cisplatin affect Organ of corti (irreversible)
Diuretics-Ethacrynic acid, frusemide cause Ionic changes(reversible)
6. enzymes inhibitor
COMIC CASE '
Cimetidine
Omeprazole
Metronidazole
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 6: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/6.jpg)
Isoniazid
Chloramphenicol
Ciprofloxacin
Allopurinol
Sulphonamides
Erythromycin
7. drugs metabolized by acetylation
SHIP'
Sulfonamides including dapsone
Hydralazine
Isoniazid (INH)
Procainamide
8. teratogenic drugs :major non-antibiotics
TAP CAP:
Thalidomide
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 7: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/7.jpg)
Androgens
Progestins
Corticosteroids
Aspirin & indomethacin
Phenytoin
9. therapeutic index formula
'TILE':
TI = LD50 / ED50
10. drug with low therapeutic index
'The Queen Likes to Dig Low'
Theophylline
Quinine
Lithium
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 8: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/8.jpg)
Digoxin have
11. G protein for receptors
"QISS & QIQ" (Kiss and Kick): G-proteins and their respective receptors in alphabetical order:
G-protein Q: alpha 1 receptor,
G-proteins I: alpha 2 receptor ,
G-proteins S: beta 1 receptor ,
G-protein S: beta 2 receptor
&
G-protein Q: M1 receptor,
G-protein I: M2 receptor,
G-protein Q: M3 receptor.
12. oral drugs forming insoluble complexes
TIAPS '
Read as “Tie-ups”.
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 9: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/9.jpg)
Tetracycline with Iron compounds
Antacids/Phenytoin with Sucralfate
13. autoinduction
Drugs that induce their own metabolism
Auto,Car & Rickshaw
Autoinduction -Carbamazepine & Rifampin
14. orally ineffective or less effective drugs
"Dont put PINS inside the mouth!"
Pencillin-G
Insulin
Neostigmine
Streptomycin
15. non-competitive inhibitor drugs
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 10: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/10.jpg)
A LIVE TIPS AD
A. acetazolamide
Live. Lovastatin
t. theophylline
I. Indomethacin
P. Propyl thiouracil
S. Sildenafil
A. Aspirin
D. Disulfiram
16. drygs metabolised by Acetylation
PHC IS PrimaryP-ProcainamideH-HydralazineC-ClonazepamI-INHS-SulphonamidesP-Phenelzine
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 11: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/11.jpg)
17. zero order kinetic
SWAT - Salicylate, Warfarin, Alcohol, TheophyllinePolice - PhenytoinTeam – Tolbutamide
18. LIVER ENZYME INDUCERS
SB CCPR
SULFAPYRAZONEBARBITURATESCHRONIC ALCOHOLCARBAMEZEPINEPHENYTOINRIFAMPICIN
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 12: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/12.jpg)
19. Enzyme inducers
GPRS Cell Phone
G-GriseofulvinP-PhenytonR-RifampicinS-SmokingC-CarbamazepineP-Phenobarbitone
20. acetylation drugs
DSHIP=DAPSONE,SULPHONAMIDE,HYDRALAZINE,INH,;;;PROCAINAMIDE
21. . Gi mediated receptors
MAD 2
Type 2 receptor of
MuscarinicAlphaDopamine
Act through GPCR with Gi as Gprotein
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 13: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/13.jpg)
22. camp as second messenger
beta c amp glue lubricates so many thyroidsBeta- beta agonists,C-CRH,calcitonin,hCG,a-alpha2 agonist, ACTH,ADH,m-MSH,p-PTH,glue-glucagon,Lubricates-LH,somany-somatostatin,Thyroid-TSH
23. TORSADES DE POINTES
QUEEN IS SONALI, , PRIYANKA, ASIN, AMRITHA, or KAZOLE:
QUINIDINEDISOPYRAMIDESOTOLOLPROCAINAMIDEARSENIC OXIDEAMIADARONEAZOLES
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 14: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/14.jpg)
24. microsomal enzyme inhibitor
PEACOCK VALA
P: PHENYLBUTAZONEE: ERYTHROMYCINA: ALLOPURINOLC: CIPROFLOXACINO: OMEPRAZOLEC: CIMETIDINEK: KETOCONAZOLEVALA: VAPROATE
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 15: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/15.jpg)
25. Drugs with high hepatic extraction ratios
"I've pickl'd Pam" or "I pickled vamp" if you prefer.
ImipramineVerapamilEtomidate
PropofolIsoniazidChlorpromazineKetamineLidocaineDiltiazem
PropranololAmitriptylineMorphine
Also might help to remember there are three induction agents - propofol/ketamine/etomidate, four antiarrhythmics - verapamil/diltiazem/propranolol/lidocaine and five nerve-y drugs - amitriptyline/imipramine/chlorpromazine/morphine/isoniazid (neurotoxic!)
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 16: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/16.jpg)
26. competitive inhibition
Km is increased in Kompetitive inhibition
27. hit n run drugs
ROGI -R- RESERPINEO-OMEPRAZOLE G-GUANTHIDINEI-INHIBITERS[MAO]
28. EXAMPLES OF ACTIVE DRUG PRODUCING ACTIVE METABOLITES
Chief Minister ADD CIA
trichloroethanolChlorhydrate
Morphine 6-glucuronideMorphine
AlloxanthineAllopurinol
oxazepamDiazepam
digoxinDigitoxin
morphineCodeine
desipramineImipramine
NortriptylineAmitriptyline
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 17: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/17.jpg)
29. EXAMPLES OF PRODRUG PRODUCING ACTIVE METABOLITES
LEADS
Levodopa dopamine
Enalapril enalaprilat
Alphamethyldopa alphamethylnorepinephrine.
Dipivefrine epinephrine
Sulindac sulfide metabolites
30. DRUGS METABOLISED BY METHYLATION
Cindy Has A New MotorC aptoprilH istamineA drenalineN icotinic acidM ethyldopa
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 18: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/18.jpg)
Ans Pharma
1. beta 1 selectibe bloker
A-BEAM
Acebutalol
Betaxolol
Esmolol
Atenolol
Metprolol
2.uses of propranolol
HATE THE PAST
Headach
Angina
Tension
Essential trmors
Tensional headach
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 19: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/19.jpg)
Hyperthyroidism
Elevated B.P
Phobia
Anxiety
Stress
Traumatic stress
3.contraindication of propranolol
ACID
Asthma
COPD
Imbalance of electrolyte
Diabetic mellitus
4. adverse affects of beta blockers
BBC Loses Viewera In Rawalpindi
Bradycardia
Bronchospasm
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 20: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/20.jpg)
Lipids (increased)
Vivid dreams
Impotency
Reduced sensitivity to hypoglycemia
5. non –selective beta blockers
PANTOP
Prapranolol
Alprenolol
Nadolol
Timolol
Oxprenolol
Pindolol
6. cardioselective beta blockers
CaN BEAM"
Celiprolol
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 21: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/21.jpg)
Nebivolol (most selective)
Bisoprolol, Betaxolol
Esmolol
Atenolol, Acebutolol
Metoprolol
7. beta blockers with instrinsic sympathetic activity (ISA)
Think: They "COntain Partial Agonistic Activity"
Celiprolol, Oxprenolol
Pindolol, Penbutolol
Alprenolol
Acebutolol
8. receptors of heart
2 Beautiful hearts Marry 2 Be 1"
B2 receptor (adrenergic)
M2 receptor (cholinergic) and
B1 receptor (adrenergic)
9. morphine vs amphetamine. Pupils in overdoses
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 22: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/22.jpg)
MorPHINE is Fine & AmPHETamine is Fat !"
Morphine overdose: pupils constricted (fine)
Amphetamine overdose: pupils dilated (fat)
10. anticholinergic side effects
"Know the ABCD'S of anticholinergic side effects":
Anorexia
Blurry vision
Constipation/ Confusion
Dry Mouth
Sedation/ Stasis of urine
11. antimuscrinic drugs and their action
Inhibits Parasympathetic And Sweat ":
IIpratropium
Pirenzepine
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 23: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/23.jpg)
Atropine
Scopolamine
12. edrophonium vs pyridostigmine in myasthenia gravis
eDrophonium is for Diagnosis
And pyRIDostigmine is to get RID of symptoms
13. MOA of tacrine and edrophonium
TEA ":
Tacrine and Edrophonium attach only to Anionic site of enzyme,Cholinesterase(ChE)
( Organophosphates attach only to the estatrtic site of Cholinesterase )
14. reversible anticholinesterases
Car PPENDoRi ": Read as "carpentry"
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 24: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/24.jpg)
Reversible Anticholiesterases belonging to Carbamates are
Physostigmine
Pyridostigmine
Edrophonium
Neostigmine
Donepezil
Rivastigmine
15. Muscarinic effects
SLUG BAM ":
Salivation/ Secretions/ Sweating
Lacrimation
Urination
Gastrointestinal upset
Bradycardia/ Bronchoconstriction/ Bowel movement
Abdominal cramps/ Anorexia
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 25: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/25.jpg)
Miosis
16. nicotinic affects
" MTWThF in rhythm "(days of week):
Mydriasis/ Muscle cramps
Tachycardia
Weakness
Twitching
hypertension/ hyperglycemia
Fasiculation
17. cholinergic affects on bowl and bladder
Call inergic/Cholinergic makes us attend natures call ! ":
ie.,Evacuation of Bowel and Bladder
18. organophosphates eefects ( Cholinergic)
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 26: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/26.jpg)
"If you know these, you will be LESS DUMB Choline ":
Lacrimation
Excitation of nicotinic synapses
Salivation
Sweating
Diarrhea
Urination
Micturition/Miosis
Bronchoconstriction
19. cholinergic agonists
Esters: A-MCB
ACh ,Methacholine ,Carbechol ,Bethanechol
Alkaloids: PMA
:Pilocarpine, Arecoline, Muscarine
20. autoreceptors
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 27: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/27.jpg)
Au to receptors ":
The' to' rhymes with 2.So the Autoreceptors are Alpha 2 (for adrenergic pathway) and M2 (for cholinergic pathway)
21. cholinergic receptor
MuGNiL":
Muscarinic :G protein coupledNicotinic :Ligand gated ion channel
22. botulinus toxin action
Think: Botulinum toxin Bottles up Acetyl choline (ACh).
It means, botulinum toxin blocks exocytic release of ACh from the synaptic vesicles at the neuromuscular junction leading to flaccid paralysis.
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 28: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/28.jpg)
23. inhibiton of choline uptake during Ach synthesis
H-I-C-Up "Hemicholinium Inhibits Acetyl Choline Uptake
24. site of acetyl choline release
"PreACh ":
Acetyl Choline ( ACh ) is released from all Pre ganglionic fibres of ANS
25. physostigmine vs neostigmine
"LMNOP":
Lipid soluble
Miotic
Natural
Orally absorbed well
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 29: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/29.jpg)
Physostigmine
26. atropine use : tachycardia or bradycardia
A goes with B": Atropine used clinically to treat Bradycardia.
27. reserpine action
Reserpine depletes the Reserves of catecholamines [and serotonin].
28. ipratropium action
Atropine is buried in the middle: iprAtropium, so it behaves like Atropine.
29. succinylcholine uses
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 30: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/30.jpg)
Succinylcholine gets Stuck to Ach receptor, then Sucks ions in through open pore.You Suck stuff in through a mouth-tube, and drug is used forintubation.
30. depression causing drugs
PROMS:PropranololReserpineOral contraceptivesMethyldopaSteroids
31. direct sympathomimetic catecholamine
DINED:DopamineIsoproterenolNorepinephrineEpinephrineDobutamine
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 31: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/31.jpg)
32. Morphine: side-effects MORPHINE:MyosisOut of it (sedation)Respiratory depressionPneumonia (aspiration)HypotensionInfrequency (constipation, urinary retention)NauseaEmesis
33. Bromocriptine [for USA gang members] The CRYPTS arean LA street gang that likes to smoke DOPE.BromoCRYPTine is a DOPamine agonist.
34. Guanethidine: mechanism GuaNEthidine prevents NE(norepinephrine) release.
35.
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 32: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/32.jpg)
Parasympathetic vs. sympathetic neurotransmitters "Nosympathy for a Pair of Aces":Norepinephren is secreted in by the Sympathetic nervous systemwhile Acetylcholine is secreted in the Parasympathetic nervoussystem.
36.
Morphine: effects at mu receptor PEAR:Physical dependenceEuphoriaAnalgesiaRespiratory depression
37.
Prazocin usage Prazocin sounds like an acronym of "praszzzour urine".Therefore Prazocin used for urinary retention in BPH.
38.
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 33: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/33.jpg)
Beta blockers with CYP2D6 polymorphic metabolism "I MetTim Carver, the metabolic polymorph":· The following beta blockers require dose adjustment due to CYP2D6 polymorphicmetabolism:MetoprololTimololCarvedilol(in patients with lower or higher than normal CYP2D6 activity)
39.
alpha blockers uses
harry potter sees 2 BP and PIPE
harry=hypertensionpotter=pheochromocytomasees2= secondary shockBP= benign hypertrophy of prostatePIPE= penile impotence
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 34: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/34.jpg)
40. Parasympathetic action
Parasympathetic action@SLUDD + 3D’sSalivationLacrimationUrination (so Anticholinergics cause urinary retension)DigestionDefecation3 important DecreasesDecrease in heart rate and contractilityDecrease in pupil size i.e. MiosisDecrease in airway size (so anticholinergics given in COPD)
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 35: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/35.jpg)
41. Physostigmine vs. neostigmine
@ LMNOP: Lipid soluble Miotic Natural Orally absorbed well Physostigmine • Neostigmine, on the contrary, is: Water soluble Used in myesthenia gravis Synthetic Poor oral absorption
42. cholinergic classification
MAP of ABC M= muscarineA= arecolineP= pilocarpineofA= acetylcholineB= bethanecholC= carbachol
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 36: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/36.jpg)
43. reversible anticholinesterase
NEW GALLANT DON ED TAKES REVERSE SPY
NEW= neostigmineGALLANT= galantamineDON= donepezilED= edrophoniumTAKES= tacrineREVERSE= rivastigmineSPY= pyhsiostigmine/ pyridostigmine
( gallant means brave)
44. alpha 1 agonists
M.MNOP
M-methoxamineM-midodrineN-naphazolineO-oxymetazolineP-phneylephrine
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 37: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/37.jpg)
45. beta-1 selective blocker
NAME-ABC
N-nebivololA-atenololM-metoprolol*E-esmolol
A-acebutanolol**B-betaxololC-celiprolol**
*drug having membrane stabilising activity also.
** drug having membrane stabilising as well as intrinsic sympathomimic action
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 38: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/38.jpg)
46 Cardioselective Beta Blockers
New Beta Blockers Acting Exclusively At Myo CardiumNebivolol(most cardioselective)BetaxololBisoprololAtenololEsmololAcebutololMetoprololCeliprolol
47. cholinergic crisi
DUMBELSS
DiarrhoeaUrinationMiosisBronchospasmExcitation cns and neuromuscularLacrimationSweatingSalivation
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 39: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/39.jpg)
48. lipid insoluble b blocker
Not soluble a b c
NadololSotalolAtenolo acebutololBetaxolol bisoprololCeliprolol
49. CARDIOSELECTIVE B BLOCKER
ameba
ATENOLOLMETOPROLOLESMOLOLBETAXOLOLACEBUTALOL
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 40: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/40.jpg)
50. reversible Anticholinestrases
ANTI- ANTICHOLINESTERASERaGING -
REVERSE,RIVASTIGMINE POLICE- PHYSIOSTAGMINE
TAKE -TACRINEGREAT -GALANTAMINE
DON –DONEPEZIL
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 41: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/41.jpg)
51. Uses of beta blockers
HM HAT CM CD PAGEH-HypertensionM-Myoardial infarction H-Hypertrophy obstructive cardiomyopathyA-Angina pectorisT-ThyrotoxicosisC-Congestive Heart failureM-MigraineC-Cardiac arrythmiasD-Dissecting aortic aneurysmP-PheochromocytomaA-AnxietyG-GlaucomaE-Essential tremors
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 42: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/42.jpg)
52. Effects of Beta blockers on Heart and Bloodvessels
SORAB got CHFS- Prolong SystoleO- Dec Oxygen consumptionR- Dec Refractory period of myocytesA- Dec automaticityB- Dec SBP nd DBP on Chr AdministrationC- Dec Cardiac output, Cardiac work & total coronary blood flowH- Dec Heart rateF- Dec Force of contraction
53. Beta blockers contra in renal failure
"ANS"
AtenololNadololSotalol
54. sympathomimetic hypertensives
Many- MephenteraminePeople- PhenylephrineNever- NoradrenalineMarry- Methoxamine
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 43: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/43.jpg)
55. zero order kinetics-ITS AWESOM
text WHATT are these drugs.
W- warfarinH- hydantoinA- aspirinT- tolbutamideT- theophylline
56. ADRENALIN
ADRENALIN USESABC HILA-ANAPHYLACTIC SHOCKB-BRONCHOSPASMC-CARDIAC ARRESTH-HEAMOSTATIC AGENTI-INSULIN INHIBITIONL-LOCAL ANAESTHETIC
57. AGONISTS OF DOPAMINE
B-BROMOCRIPTINEA-ANTICHOLINERGICS(CENTRAL)L-LEVODOPA
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 44: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/44.jpg)
CVS PHARMA
1. aspirin side affects
"ASPIRIN"
Asthma
Salicylism
Peptic ulcer / Premature closure of PDA
Intestinal blood loss
Reye's syndrome
Idiosyncracy
Noise (tinnitus)
2. hypertension management
"ABCD"
ACE inhibitors/Angiotensin receptor blockers
Beta blockers
Calcium channel blockers
Diuretics
3. amiodarone : adverse affects
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 45: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/45.jpg)
Plz Check PFT, LFT, TFT "
Plz- Photosensitivity, Pigmentation
Check for Corneal deposits
PFT- Pulmonary fibrosis
LFT- Liver damage (pseudoalcoholic liver injury)
TFT- Thyroid dysfunction
4. antihypertensive : contraindicated in pregnancy
DARSAN '
Diuretics
Angiotensin I antagonists
Reserpine
Sodium nitroprusside
ACE inhibitors
Non selective β blockers
5. antiarrythmic drugs: clases
" i' M BAC in rhythm ":
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 46: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/46.jpg)
I.Membrane stabilizing agents (Na channel blockers)II.Beta blockers (Antiadrenergic agents)III.Agents widening APIV.Calcium channel blockers
6. receptors of heart
"2 Beautiful hearts Marry 2 Be 1"
B2 receptor (adrenergic)
M2 receptor (cholinergic) and
B1 receptor (adrenergic)
7. patent ductus arteriosus treatment
Come IN and Close the Door":
INdomethacin is used to Close the PDA.
8. ca ++ channel blocker:uses
Ca++ MASH:
Cerebral vasospasm/ CHF
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 47: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/47.jpg)
angina
Migraine
Atrial flutter, fibrillation
Supraventricular tachycardia
Hypertension
9. > Captopril (an ACE inhibitor): side effects CAPTOPRIL:CoughAngioedema/ AgranulocystosisProteinuria/ Potassium excessTaste changesOrthostatic hypotensionPregnancy contraindication/ Pancreatitis/ Pressure drop (first dose hypertension)Renal failure (and renal artery stenosis contraindication)/ RashIndomethacin inhibitionLeukopenia/ Liver toxicity
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 48: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/48.jpg)
10. > Warfarin: metabolism SLOW:∙ Has a slow onset of action.∙ A quicK Vitamin K antagonist, though.Small lipidsoluble moleculeLiver: site of actionOral route of administration.Warfarin
11. > Amiodarone: action, side effects 6 P's:Prolongs action potential durationPhotosensitivityPigmentation of skinPeripheral neuropathyPulmonary alveolitis and fibrosisPeripheral conversion of T4 to T3 is inhibited > hypothyroidism
12. > Clopidogrel: use CLOPIdogrel is a drug that preventsCLots, an Oral Platelet Inhibitor (OP
13. > Warfarin: action, monitoring WePT:Warfarin works on the extrinsic pathway and is monitored by PT.
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 49: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/49.jpg)
14. Enoxaprin (prototype low molecular weight heparin): action, monitoring EnoXaprin only acts on factor Xa.Monitor Xa concentration, rather than APTT.
14. > Thrombolytic agents USA:UrokinaseStreptokinaseAlteplase (tPA)
15. > Antiarrhythmics: classification I to IV MBA College∙ In order of class I to IV:Membrane stabilizers (class I)Beta blockersAction potential widening agentsCalcium channel blockers
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 50: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/50.jpg)
16. > HMGCoA reductase inhibitors (statins): side effects, contraindications, interactions HMGCoA:∙ Side effects:HepatotoxicityMyositis [aka rhabdomyolysis]∙ Contraindications:Girl during pregnancy/ Growing children∙ Interactions:Coumarin/ Cyclosporine
17. > Antiarrhythmics: class III members BIAS:BretyliumIbutilideAmiodaroneSotalol
18. > ACEI: contraindictions PARK:PregnancyAllergyRenal artery stenosisK increase (hyperkalemia)
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 51: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/51.jpg)
19. > Endotrachial tube deliverable drugs O NAVEL:OxygenNaloxoneAtropineVentolin (albuterol)EpinephrineLidocaine∙ If you can't get IV access established, and have necessity to administer resuscitative meds, remember you have the airway and can give the above drugs.∙ Drug delivery is enhanced if diluted with 10cc NS and rapid introduced for aeresolization.∙ Alternatively, bare bone version is ALE, as above.
20. SVT Causes SNAPSinus tachy, nodal tachy, a fib, paroxysmal atrial tachy
21. Arrhythmias
ARHYTHMIAL 4PC
Atrial Myxoma
Rh heart dis
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 52: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/52.jpg)
Hypertension
THyrotoxicosis
Mitral valve dis
IHD,
Alcohol
Pneumonia / PE / Pericardial eff, cardiomyopathy
22. > Atrial Fibrillation
ARITHMATIC
Alcohol
Rh fever
IHD
Thyrotoxicosis
Hypertension
Mitral stenosis / MI / Myxoma(atrial)
ASD
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 53: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/53.jpg)
Toxins,
Idiopathic/Infective endocarditis
Cardiomyopathy/Constrictive pericarditis
23. Sinoatrial node: innervations
Sympathetic acts on Sodium channels (SS).
Parasympathetic acts on Potassium channels (PS).
24. > Supraventricular tachycardia: treatment ABCDE:AdenosineBetablockerCalcium channel antagonistDigoxinExcitation (vagal stimulation)
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 54: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/54.jpg)
25. > Ventricular tachycardia: treatment LAMB:LidocaineAmiodaroneMexiltene/ MagnesiumBetablocker
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 55: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/55.jpg)
26. > Sinus bradycardia: aetiology "SINUS BRADICARDIA" (sinus bradycardia):SleepInfections (myocarditis)Neap thyroid (hypothyroid)Unconsciousness (vasovagal syncope)Subnormal temperatures (hypothermia)Biliary obstructionRaised CO2 (hypercapnia)AcidosisDeficient blood sugar (hypoglycemia)Imbalance of electrolytesCushing's reflex (raised ICP)AgingRx (drugs, such as highdose atropine)Deep anaesthesiaIschemic heart diseaseAthletes
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 56: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/56.jpg)
27. > Atrial fibrillation: causes PIRATES:Pulmonary: PE, COPDIatrogenicRheumatic heart: mirtral regurgitationAtherosclerotic: MI, CADThyroid: hyperthyroidEndocarditisSick sinus syndrome
28. > Atrial fibrillation: management ABCD:AnticoagulateBetablock to control rateCardiovertDigoxin
29. > Atrial fibrillation: management ABCD:AnticoagulateBetablock to control rateCardiovertDigoxin
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 57: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/57.jpg)
30. > Sinus tachycardia TACH FEVER:Tamponade/ ThyrotoxicosisAnemiaCHFHypotensionFeverExcrutiating painVolume depletionExerciseRx (Theo, Dopa, Epi, etc)
31. Vfib/Vtach drugs used according to ACLS "Every Little Boy Must Pray":EpinephrineLidocaineBretyliumMagsulfateProcainamide
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 58: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/58.jpg)
32. > Ventricular fibrillation: treatment "Shock, Shock, Shock, Everybody Shock, Little Shock, Big Shock, Momma Shock, Poppa Shock":Shock= DefibrillateEverybody= EpinephineLittle= LidocaineBig= BretyliumMomma= MgSO4Poppa= Pocainamide
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 59: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/59.jpg)
33. > Atrial fibrillation: causes of new onset THE ATRIAL FIBS:ThyroidHypothermiaEmbolism (P.E.)AlcoholTrauma (cardiac contusion)Recent surgery (post CABG)IschemiaAtrial enlargementLone or idiopathicFever, anemia, highoutput statesInfarctBad valves (mitral stenosis)Stimulants (cocaine, theo, amphet, caffeine)
34.
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 60: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/60.jpg)
> PEA/Asystole (ACLS): etiology ITCHPAD:InfarctionTension pneumothoraxCardiac tamponadeHypovolemia/ Hypothermia/ Hypo, Hyperkalemia/ Hypomagnesmia/ HypoxemiaPulmonary embolismAcidosisDrug overdose
35. > Hypertension: secondary hypertension causes CHAPS:Cushing's syndromeHyperaldosteronism [aka Conn's syndrome]Aorta coarctationPhaeochromocytomaStenosis of renal arteries∙ Note: only 5% of hypertension cases are secondary, rest are primary
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 61: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/61.jpg)
36. > Preeclampsia: classic triad PREeclampsia:ProteinuriaRising blood pressureEdema
37. > Postural Hypotension
HANDI
Hypovolaemia / hypopituitarism,
Addisons
Neuropathy (autonomic)
Drugs (vasodilators /TCADs, diuretics, antipsychotics),
Idiopathic
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 62: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/62.jpg)
38. > Deep venous thrombosis: genetic causes ALASCA:Antithrombin IIILeiden (Factor V)APC (Activated Protein C)Sprotein deficiencyCprotein deficiencyAntiphospholipid antibody
39. > Deep venous thrombosis: diagnosis DVT:Dilated superficial veins/ Discoloration/ Doppler ultrasoundVenography is gold standardTenderness of Thigh and calf
40. > Virchow's triad (venous thrombosis) "VIRchow":Vascular traumaIncreased coagulabilityReduced blood flow (stasis)
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 63: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/63.jpg)
41. > Myocardial infarct, complications ABCDE x2Arrhythmias / AneurysmBradycardia / ↓BPCardiac failure / cardiac tamponadeDresslers / Death!Embolism / Extra (VSD, pap muscle rupture)
42. Lines of treatment of pulmonary oedema:
DOLMA
Digoxin, Oxygen, Lasix, Morfine, Aminophylline. (Dolma is a very famous food in the middle east.)
43. > M.O.N.A“MONA” treatment for acute MI.Morphine, Oxygen, Nitrate, Aspirin
44. > Coronary artery bypass graft: indications DUST:Depressed ventricular functionUnstable anginaStenosis of the left main stemTriple vessel disease
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 64: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/64.jpg)
45.
> Acute Coronary Syndrome: initial treatment ABCD:AspirinBeta blockerCoagulation (anticoagulation with heparin/LMW Heparin)Double product control (decrease heart rate and blood pressure)
46.
> MI: therapeutic treatment "O BATMAN!":OxygenBeta blockerASAThrombolytics (eg heparin)MorphineAce prnNitroglycerin
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 65: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/65.jpg)
47. > Atherosclerosis risk factors "You're a SAD BET with these risk factors":Sex: maleAge: middleaged, elderlyDiabetes mellitusBP high: hypertensionElevated cholesterolTobacco
48.
> Thrombus: possible fates DOPE:DissolutionOrganization & repairPropagationEmbolization
49.
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 66: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/66.jpg)
> Cardiovascular risk factors FLASH BODIES:Family historyLipidsAgeSexHomocystinaemiaBlood pressureObesityDiabetes mellitusInflammation (raised CRP)/ Increased thrombosisExerciseSmoking
50. MI: immediate treatment DOGASH:DiamorphineOxygenGTN sprayAsprin 300mgStreptokinaseHeparin
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 67: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/67.jpg)
51. Centrally acting anti-hypertensives
M - Methyld dopa
R - Reserpine
C - Clonidine
P – Propranolol
52.
AMIODARONE - IMPORTANT SIDE EFFECTS
PCT - PROXIMAL CONVULATING TUBULE
P - PULMONARY FIBROSISC- CORNEAL MICRODEPOSITST- THROID DISORDERS (hypo/hyperthyroidism)
53. diuretic decreases calcium
which diuretic loses calcium in urine..LOOPS LOSE CALCIUM
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 68: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/68.jpg)
54. Side Effects of Aspirin
ASPIRIN A: Allergy like reactions e.g. UrticariaS: susceptibility to bleedingP: Peptic ulcerI: Idiosyncratic reactionsR: Reye's syndromeI: rInging in the ears(tinnitus)N: Nephropathy
55. Side Effects of Thiazide Diuretics
Mnemonic : HYPER GLUC
Hyper = Increased
G = GlucoseL = Light-headedness (orthostatic hypotension/ low vol/ low sodium) U = UricemiaC = Calcemia
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 69: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/69.jpg)
56. Anti-hypertensives used in emergencies
Saurav Ganguly HELPS-sodium nitroprussideG-GlyceryltrinitrateH-hydralazineE-esmololL-labetalolP-phentolamine
57. anti-hypertensives giving in pregnancy
anti-hypertensives given in pregnancy -3Cs -Ca channel blocker,cardioselective b-blocker,central sympatholytic-clonidine.
58. Nitric oxide donors
Highly Pro Nitric
H:HydralazineP:PropofolN:Nebivolol
And the rest :Na nitroprusside,Organic nitrates,Nitrites.
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 70: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/70.jpg)
59. heparin
H=HYPERSENSITIVITY & hyperkalemiaE=excessive beedingP=PROLONG APTTA=ALOPECIAR=REDUCED PLATELET & BONE MASSi.e.thrombocytopenia osteoporosisI=i.v. routeN=aNtagonise by protamine sulphate
60. digitalis
Digitalis toxicity is aggravated by KOMAR (READ IT AS KUMAR) of CaLIFORNIA
KOM-hypoka,hypoxe,hypomagAdvance ageReanal insufficiencyCalifornia in block letters suggest hyperCALCEMIA
KEEP ON REVISING...
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 71: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/71.jpg)
61. drugs contraindicated in heart failure
Napolean _Narcotics including OpioidsBonaparte _BenzodiazepinesSays_Salicylates Hello_HypnoticsTo _TranquilizersDon_Diuretics
62. fibrinolytics
STUART
S-STREPTOKINASET-TENECTEPLASEU-UROKINASEA-ALTEPLASER-RETEPLASEt
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 72: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/72.jpg)
63. Side effects of Spironolactone
I May Have Got Additional Potassium.
I=ImpotenceM=Menstrual irregularitiesH=HirsuitismG=GynaecomastiaA=AcidosisP=Peptic ulcer(aggravates)
And last but not the least is the pnemonic itself states the main side-effect=Hyperkalemia
64. antiarrythmic class I A
Queen Proclaims Diso'sPyramidQUINIDINEPROCAINAMIDEDISOPYRAMIDE
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 73: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/73.jpg)
65. antiarrythmic class I B
IBuy Lido's Mexican Toffees
IB=LidocaineMexileteneTocainide
66. antiarrythmic class I CFleeting Programme MakerFlecainidePropafenoneMoricizine
67. K sparing diuretscs
EAST
Epleranone
Amiloride
Spironolactone
Triameterene
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 74: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/74.jpg)
Chemo-Pharma
1. Antibiotics contraindicated during pregnancy
MCAT:
Metronidazole
Chloramphenicol
Aminoglycoside
Tetracycline
2. Etoposide: action, indications, side effect
"eTOPoside":
· Action:
Inhibits TOPoisomerase II
· Indications:
Testicular carcinoma
Oat cell carcinoma of lung
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 75: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/75.jpg)
Prostate carcinoma
· Side effect:
Affects TOP of your head, causing alopecia
3. Bleomycin: action
"Bleo-Mycin Blows My DNA to bits":
Bleomycin works by fragmenting DNA (blowing it to bits).
My DNA signals that its used for cancer (targeting self cells)
4. major side effects of isoniazid
isoniazid or isonicotinic acid hydrazide(INH) I-INSANITY(psychosis)N-NEURITIS(peripheral neuritis)H-HEPATITIS
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 76: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/76.jpg)
5. antipseudomonal aminoglycosides
a small one. antipseudomonal aminoglycosides:
mnemonic: TAG
T: tobramycin
A: amikacin
G: gentamycin
6. antifungals-DOCs
amphotericin B- SAM (name)S-SporotrichosisA-ActinomycosisM-MucormycosisItraconazole PChB (phy,chem,bio)P-ParacoccididomycosisCh-chromomycosisB-BlastomycosisAmpho+5FC DC & CC (jingle)DC-dissem. candidiasisCC-cryptococcosisamph/itr HP-histoplasmosis
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 77: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/77.jpg)
7. METRONIDAZOLE-SPECTRUM OF ACTION
SPECTRUM OF ACTIONA-AmoebiasisB-Bacteroides fragilisC-Clostridium perfringensD-Dracunculus medinensisE-Pseudomembranus EnterocolitisF-FusobacteriumG-GiardiasisH-Helicobacter PyloriS-Anaerobic StreptococciT-Trichomonas
8. Rifampin
4R'sRNA polymerase inhibitorRevs up Microsomal P450Red/Orange body fluidsRapid Resistance if used alone
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 78: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/78.jpg)
9. Uses of cotrimoxazole
Utre: Urinary Tract Infections Reti: Respiratory tract infectionsparTight: TyphoidBody: Bacterial Diarrhoeas & Dysenterylekar, jabChance: ChancroidGine: Granuloma InguinaleAp: Agranulocytosis patientsPC: Pneumocystis cariniipar
10. s/e of tetracyclines
KAPIL DeV to BATK - Kidney damageA - Antianabolic effectP - PhotoxicityI - Increased intracranial pressureL - Liver damageDe - Diabetes insipidusV - Vestibular toxicitytoBAT - Bones And Teeth
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 79: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/79.jpg)
11. Adverse effects of chloramphenicol
Adverse effects of Chloramphenicol-
BIG Super Hypersensitivity
B- Bone marrow depression
I- Irritative effects like nausea, vomiting, diarrhoea, pain on injection
G- Gray baby syndrome
Super- super infections
Hypersensitivity reactions like rashes, fever, angioedema
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 80: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/80.jpg)
12. uses of tetracyclines
Uses of tetracyclines - (used as 1st choice drugs in- )V Are B.R. Chopra Productions
V -Venereal diseases (lymphogranuloma venerum and granuloma inguinale)
Are- Atypical pneumonia due to mycoplasma pneumoniae
B - brucellosis tretment
R- Rickettsial infections, Relapsing fever
Chopra- Cholera
Productions- Plague
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 81: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/81.jpg)
13. bactericidal drugs
I M Bactericidal Because A Very Quiet Person is Rarely Protected
IsoniazidMetronidazoleBeta lactamsBacitracinAminogycosidesVancomycinQuinolonesPyrazinamideRifampinPolymyxin
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 82: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/82.jpg)
14. bacteriostatic drugs
Static Causes Non Total Or Non Complete Though Massive Elimination
SulfonamidesChloramphenicolNitrofurantoinTetracyclinOxazolidinonNovobiocinClindamycinTrimethoprimMacrolideEthambutol
15. antibiotics c/I in pregnancy
SAFETYS - SULPHONAMIDESA - AMINOGLYCOSIDESF - FQsE - ERYTHROMYCIN ESTOLATET - TETRACYCLINY – clindamYcin
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 83: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/83.jpg)
16.antitubeculosis drugs
SPIRE
S..............STREPTOMYCINP...............PYRIZINAMIDEI...............ISONIAZIDER,.............RIFAMPICINE...............ETHAMBUTOL
17. macrolides
RACER-roxithromycinA-azitromycinC-clarithromycinE-erythromycin.
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 84: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/84.jpg)
18. Antitubercular drugs. K.D.Tripathi
¤First line drugs.(PRIEST)PyrazinamideRifampinIsoniazidEtambutolSTreptomycin¤second line drugs(Please TAKE Carbon Copy)Paraamino salicylic acidThiacetazoneAmikacinKanamycinEthinamideCapreomycineCycloserine¤Newer drugs.(CAR Of Century)CiprofloxacinAzithromycinRifabutin OfloxacinClarithromycin
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 85: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/85.jpg)
19. anti psedomonal drugs
Amin Beta Pseudo Polyp Roq!
Amin-Aminoglycosides
Beta-beta lactams
Pseudo-pseudomonas
Roq-fluoROQuinolones
20. ADR of Interferons
MY FAITH is NEUROTOXICMY-MYelosuppressionF-Flu like symptomsA-AlopeciaI-Interstitial nephritisT-ThyroiditisH-HepatotoxicityisNEUROTOXIC
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 86: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/86.jpg)
21. Penicillin DOC in
"P.M.(Prime Minister) Pass List of An Strict Act of Superfast Train's Tt."P-PneumococciM-Meningococcal meningitisPass-Pasturella multocidaList-ListeriaAn-AnthraxStrict-StreptococciAct-ActinomycesSuperfast-SyphillisTrain's-Trench feverTt-Tetanus
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 87: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/87.jpg)
22. Anticancer drugs
From K.D. TripathyALKYLATING AGENTS: TANEN / NEAT NTriazine: DacarbazineAlkyl Sulfonate: BusulfanNitrosoureas: CarmustineLomustineEthylenimine: Thio- TEPANitrogen Mustards: MCI CMMechlorethamineCyclophosphamideIfosfamideChlorambucilMelphalanVECTAVinca Alkaloids: VincristineVinblastineEpipodophyllotoxin: EtoposideCamptothecin Analogues: Irinotecan TopotecanTaxanes: PaclitaxelDocetaxelAnti metabolites: Folate Antagonist: MethotrexatePurine Antagonist: F ATM Fludarabine Azathioprine6- Thioguanine6- MercaptopurinePyrimidine Antagonist: 5- FUCytarabineMedic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 88: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/88.jpg)
Antibiotics: ADD MMB/ DMD MBAActinomycin DDoxorubicinDaunorubicinMitomycin CMitoxantroneBleomycinMisc: HPCL IHydroxyureaProcarbazineCisplatinCarboplatinL- AsparaginaseImatinibLastly Drugs altering Hormonal Milieu
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 89: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/89.jpg)
23. erythromycin uses
it is used against..' pure dairy white chocolate'pure- pneumoniadairy- diphtheriawhite- whooping coughchocolate- chancroid
24. ANTI-MALARIAL DRUGS
"A Q can B D Answer Surely bt Teacher make's Answer NonSense"
4-aminoquinolinesquinoline-methanolcinchona alkaloidsbiguanadesdiaminopyramidines8-aminoquinolinesulfonamides nd sulfonetetracyclinesamino alcoholsnaphthoquinonesesquiterpine lactones
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 90: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/90.jpg)
25. SULPHONAMIDES
SULPHONAMIDESS=Steven johnson syndromeU=urtecariaL=LeukopeniaP=Photo-sensitivityH=Haemolytic anemia/HepatitisO=Oobstruction of urinary tractN=Nausea,Vomiting,diarrhea?NephritisA=AgranulocystosisM=Malaise/Megaloblastic aneamiaI=Increase risk of Kernicterus in new bornD=Depression?drug feverE+EosinophiliaS=Skin rashes
26. antibiotic action on protien synthesis
Buy at 30 sell at 50
At aminogycoside tetracycline 30 s ribosome
Sell streptomycin erythromycin lincosamide linasolide 50 s ribosome
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 91: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/91.jpg)
27. Doxycycline DOC
RELY on RICH doxyRElapsing feverLYmes diseaseRIkketsial infectionsCHlamydial infections
conditions where Doxycycline is drug of choice
28. penicillinase resistant penicillin
C - cloxacillin
O - oxacillin
N - nafcillin
D - dicloxacillin
O
M – mezlocillin
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 92: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/92.jpg)
29. Oncology (Monoclonal antibodies in chemotherapy)
BAC TIGeR
B-BeVacizumab A-AlemtuzumabC-Cetuximab
T-TrastuzumabI-IbrituximabG-GemtuzumabR-Rituximab
30. cepholo against bacteroids
T drugs against bacteroidsCefaTetanCefameTazoleCefaxiTin
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 93: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/93.jpg)
31. DAPTOMYCIN
DAPTOMYCIND-depolarisation ( MOA)A-all infectionsP-pulmonary surfactant is it's inhibitorTO-TO be avoided in pneumoniaMY- MyopathyCIN-CI dal (bactericidal )
32. MRSA
Drugs effective in MRSAVictoria Terminal Se Lekar Dadri Root is ClosedVancomycinTeicoplaninStreptograminsLinezolideDaptomycineCotrimoxazoleRifampicin
33. AMPHTERICIN B
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 94: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/94.jpg)
A nemiaM uscle spasmsP hlebitisH eadaches/hypotension/hypokalemiaT hrombocytopeniaE mesis, encephalopathyR espiratory stridaI ncreased temperature (fever)C hillsI mmediate hypersensitivity (anaphylaxis)N ephrotoxicity—important!B ronchospasm
34.NNRTIs (Edited, New)
Isha Virani never remembers to pin up her dress
Isha virani is for ifavirenz,never remembers is for nevirapined in the dress means delaviridine.
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 95: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/95.jpg)
35. NRTIs (New, edited)
Its for remembering NRTIs category drugs,
Abaca's (Abaca is an african negro man! just to remember) African Zoo for Ass , Lambs and Dianosaurs .
Abaca is for abacavir!Zoo is for Zalcitabine!Ass that is "a" is for "azt" and "S" is for stavudine!Lambs is for Lamivudine!Dianosaures is for Didanosine
36. ANTIVIRAL drugs are:
A Acyclovir | in herpes infection except
N Nevirapine & Nelfinavir | Nevirapine & Nelfinavir
T Trifluridine | which are used in HIV
I Idoxuridine | infection
V Vidarabine |
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 96: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/96.jpg)
I Indinavir | Protease |
R Ritonavir | inhibitors |
| in HIV
| infection
A AZT or Zidovidine | Reverse transcriptase |
L Lamivudine | inhibitors |
37. Uses of Fluoroquinolones (shared by Gajanan Taywade)
{3G SPECTRUM CT}
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 97: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/97.jpg)
3G: Gonorrhoea, Gastroenteritis & Gram -ve InfectionsS: SepticemiaP: ProphylaxisE: EnterocolitisC: ChancroidT: TyphoidR: RTIU: UTIM: MeningitisC: ConjunctivitisT: Tuberculosis
38. RIBAvirin:
RSV
Influenza B
Arenaviruses (Lassa, Bolivian, etc.)
39. Cephalosporins are active against many bacteria, but these special bacteria make them CALM (Ineffective)
remembr: CALM
C=CLAUSTRIDIUM
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 98: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/98.jpg)
A=ACTIVE ENTEROCOCCIL=LISTERIA MONOCYTOGENESM= MRSA (METHICILLIN RESISTENT STAPHYLOCOCCI
40. antihelmenthic
for tapeworm DIFFICULT - DISCHLORPHENQUESTION - QUINACRINENOT - NICLOSAMIDEANSWERED – ASPIDIUM
41. antihelminthic
for roundwormPRESS -PIPERAZINETHE -THIABENDAZOLEHANDLE - HEXYLRESORCINOLOF - OIL OF CHENOPODIUMSIDE - SENTONINDOOR – DIETHYLCARBAMAZINE
42. antibiotics,atntiviral and antifungal causing nephrotoxicity
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 99: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/99.jpg)
Mnemonic: SIGMA CAT FAG
Sulfonamides
Indinavir
Ganciclovir
Metronidazole
Acyclovir
Cidofovir
Aminoglycosides
Tetracyclines
Foscarnet
Amphoterican B
Glycopeptides (Vancomycin)
44.antibiotics inhibiting 30s vs 50s
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 100: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/100.jpg)
buy AT 30, CCELL at 50
30S:Aminoglycosides (gentamicin, amikacin, streptogramin, tobramycin) [bacteriocidal]Tetracyclines [bacteriostatic]
50S:Chloramphenicol [bacteriostatic]Clindamycin [bacteriostatic]Erythromycin [bacteriostatic]Lincomycin [bacteriostatic]Linezolid [variable]
45.target of first generation cephalosporins
PEcK
ProteusE. coliKlebsiella
46.target of 2nd generation cephalosporins
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 101: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/101.jpg)
HEN PEcKS
H. fluEnterobacterNesseria
ProteusE. coliKlebsiellaSerrati
47.side effects of vancomycin
NOT
NephrotoxicityOtotoxicityThrombophlebitis ("red man" syndrome)
48.drugs for pseudomonas
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 102: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/102.jpg)
TCP
TicarcillinCarbenicillinPiperacillin
Also 3rd gen cephs
49.spectrum of ampicillin/amoxicillin
Ampicillin/amoxicillin HELPS kill enterococci
H. fluE. coliListeriaProteusSalmonellaenterococc
50.properties og aminoglycoside
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 103: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/103.jpg)
Mean" GNATS cannot kill anerobes
"Mean" = bacteriocidalGentamicinNeomycinAmikacinTobramycinStreptomycin
Require O2 for uptake, therefore they are not effective against anaerobes
NOT
Nephrotoxic (esp when used with cephs)Ototoxic (esp when used with diuretics)Teratogen
51.tetracyclin are effective against
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 104: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/104.jpg)
VACUUM THe BedRoom
VibrioAcneChlamydiaUreaplasmaUrealyticumMycoplasmaTularemiaH. pyloriBorreliaRickettsia
52. ChloramPhenicol:The only one with a “P”, thus the only one inhibiting Peptide bond formation (by peptidyltransferase).
53. Macrolides:Prevent the Movement of ribosomes.Prevents translocation.
54. Tetracyclines (TTC):tRNA Tries but can’t.Prevents the aminoacyl-tRNA from attaching to the A site of the ribosome.
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 105: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/105.jpg)
55. Clindamycin:Makes ribosomes Cling to mRNA.Prevents translocation
CNS Pharma
1.effects via Mu opiates receptors
"SACRUM"
Sedation
Analgesia
Constipation
Respiratory depression
Euphoria
Miosi
2.antipsychotics:uses
S.O.M.A.T.I.C "
Schizophrenia
Organic brain syndromes
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 106: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/106.jpg)
Mania
Anxiety
Tetanus
Intractable cough
Control of vomiting
3.lithium adverse effects
LITHIUM"
Lethargy / Leucocytosis
Intentional Tremor
Teratogenicity
Hypothyroidism
Insipidus [Diabetes insipidus]
Urine excess
Metallic taste
4.morphine adverse effects
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 107: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/107.jpg)
MORPHINE "
Miosis
Oliguria
Respiratory depression
Pruritus
Hypotension
Infrequency (constipation)
Nausea
Emesis (Vomiting)
5.lithium uses
LIBRA '
Leukopenia
Inappropriate ADH secretion syndrome (SIADH)
Bipolar disorder
Recurrent neuropsychiatric syndrome
Agranulocytosis
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 108: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/108.jpg)
6. drugs for alzheimer
DR.GangaTejwanid=donepezilr=rivastigmineg=galantaminet=tacrine
7. s/e phenytoin
adverse effect of phenytoin:
PHENYTOIN
P-450 interactionHirsutism Enlarged gumsNystagmus Yellow skin(discolouration)Teratogenicity Osteomalacia Interference with B-12 metabolism Neuropathies-ataxia,vertigo
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 109: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/109.jpg)
8. antiepileptics' classification
B - barbiturates D-deoxybarbitaratesH - hydantoin I - iminostilbeneS - succinamide A-aliphatic carbxylic acidB -benzodiazepinesC - cyclic GABA analogueP - phenyl triazineN - newer drugs
BD HISAB Ce PiNa
9. ATYPICAL ANTIPSYCHOTICS
ORCAS (Brand names in parentheses)
Olanzapine (Zyprexa)Risperidone (Risperdal)Clozapine (Clozaril)Aripiprazole (Abilify)(Seroquel) Quetiapine
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 110: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/110.jpg)
10. Side effects of clozapine
Side effects of clozapine MASSM myocarditisA agranulocytosis*S seizuresS sialorrhea
11. short acting BZDsTOMTriazolamOnazelamMidazolam
12. Adverse effects of Diazepam
ADVERSE effects of Diazepam-DIAzEPAND-Dizziness,disorientation,dry mouthI-impaired visionA-AmnesiazE-elderlyP-Psychomotor skill impairmentA-Ataxia, apnoea in sleepN-Neonatal resp depression, night awakening
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 111: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/111.jpg)
13. PHENYTOIN ADVERSE EFFECT
HOT MALIKAH- HIRSUTISM N HYPERTROPHY OF GUMO- OSTEOMALACIAT-TERATOGENICITY
M- MEGALOBLASTIC ANEMIAA- ATAXIAL- LYMPHDENOPATHYI- INHIBIT INSULINEK- VIT K DEFICIENCYA- ARRYTHMIA
14. Adv. effects of Carbamazepine
Adv effecta of Carbamazepine(anti-epilepsy)Mnemonic- CARBA MEAN
C-ConfusionA-AtaxiaR-RashesB-Blurring of visionA-Aplastic anaemia
15.Parkinsonism management
SALAD
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 112: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/112.jpg)
Selegline
Anticholinergics(trihexyphenidyl,benztropine)
L.dopa +decarboxylase(carbidopa)
Amantididne
Dopamine receptor agonists(bromocriptine,pergolide)
16. MAOIs: indications MAOI'S:Melancholic [classic name for atypical depression]AnxietyObesity disorders [anorexia, bulemia]Imagined illnesses [hypochondria]Social phobias· Listed in decreasing order of importance.· Note MAOI is inside MelAnchOlIc.
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 113: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/113.jpg)
17. Opioids: effects BAD AMERICANS:Bradycardia & hypotensionAnorexiaDiminished pupilary sizeAnalgesicsMiosisEuphoriaRespiratory depressionIncreased smooth muscle activity (biliary tract constriction) ConstipationAmeliorate cough reflexNausea and vomitingSedation
18. SSRIs: side effects SSRI:Serotonin syndromeStimulate CNSReproductive disfunctions in maleInsomnia
19. Inhalation anesthetics SHINE:SevofluraneHalothaneIsofluraneNitrous oxideEnflurane· If want the defunct Methoxyflurane too, make it MoonSHINE.
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 114: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/114.jpg)
20. Benzodiazapines: ones not metabolized by the liver (safe to use inliver failure) LOT: Lorazepam Oxazepam Temazepam
21. Benzodiazepines: actions"Ben SCAMs Pam into seduction not by brain but by muscle":Sedationanti-Convulsantanti-AnxietyMuscle relaxantNot by brain: No antipsychotic activity.
22. Benzodiazepenes: drugs which decrease their metabolism"I'm Overly Calm":IsoniazidOral contraceptive pillsCimetidine· These drugs increase calming effect of BZDs by retarding metabolism.
23. Anesthesia: 4 stages "Anesthesiologists Enjoy S & M":AnalgesiaExcitementSurgical anesthesiaMedullary paralysis
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 115: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/115.jpg)
24. Sodium valproate: side effects VALPROATE:VomitingAlopeciaLiver toxicityPancreatitis/ PancytopeniaRetention of fats (weight gain)Oedema (peripheral oedema)Appetite increaseTremorEnzyme inducer (liver)
25. Methyldopa:side effects METHYLDOPA:Mental retardationElectrolyte imbalanceToleranceHeadache/ Hepatotoxicity psYcological upsetLactation in femaleDry mouthOedemaParkinsonismAnaemia (haemolytic)
26.benzodiazepine actions
SAMA
Sedation
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 116: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/116.jpg)
Anticonvulsive
Muscle relaxant
Anti-anxiety
27.Benzodiazepine side effects
5 As
Addiction
Additive sedation
Amnesia
Ataxia
Abjection (depression)
28. Gen anesthetics
SHINED
Sevoflurane
Halothane
isoflurane
NO
Enflurane
Desflurane
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 117: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/117.jpg)
Endocrinology
1.Pituitary hormones
FLAGTOP:Follicle stimulating hormoneLutinizing hormoneAdrenocorticotropin hormoneGrowth hormoneThyroid stimulating hormoneOxytocinProlactin
2.progestorone actions
PROGESTE:Produce cervical mucousRelax uterine smooth muscleOxycotin sensitivity downGonadotropin [FSH, LH] secretions downEndometrial spiral arteries and secretions upSustain pregnancyTemperature up / Tit developmentExcitability of myometrium down
3.Hyperthyroidism sign and symptoms
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 118: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/118.jpg)
THYROIDISM:TremorHeart rate upYawning [fatigability]RestlessnessOligomenorrhea & amenorrheaIntolerance to heatDiarrheaIrritabilitySweatingMusle wasting & weight loss
4.adrenal gland functions
ACTH:Adrenergic functionsCatabolism of proteins/ Carbohydrate metabolismT cell immunomodulationHyper/ Hypotension (blood pressure control)
5.oestrogen functions
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 119: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/119.jpg)
OESTROGEN SUX:Organ development (sex organs)Endocrine: FSH and LH regulationSecondary sex characteristics developmentTropic for pregnancyReceptor synthesis (of progesterone, oestrogen, LH)Osteoporosis decrease (inhibits bone reabsorption)Granulosa cell developmentEndocrine: increases prolactin secretion, but then blocks its effectNipple developmentSex drive increaseUterine contractility increaseoXytocin sensitivity increase
6.aldosterone:regulation of secretion from adrenal cortex
RNAsRenin-angiotensin m echanismNa concentraton in bloodANP (atrial natriuretic peptide)Stress
7.Hypercalcemia
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 120: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/120.jpg)
Bones, Stones, Groans, Moans":Bones: pain in bonesStones: renalGroans: painPsychic moans/ Psychological overtones: confused state
8.Pheocromocytoma
PHEochromocytoma":PalpitationsHeadacheEdisodic sweating (diaphoresis)
9.Thyroid carcinoma
Most Popular is Papillary.· Clinical features:Papillae (branching)Palpable lymph nodes"Pupil" nuclei (Orphan Annie)Psammoma bodies within lesion (often)· Also, has a Positive Prognosis (10 year survival rate: 98%)
10.thyroid storm
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 121: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/121.jpg)
Storm HITS girls cAMP":Thyroid storm due to:HyperthyroidismInfection or Illness at childbirthTraumaSurgery· girls: Thyroid storm more common in females.· cAMP: Tx involves high dose of beta blockers (beta receptors work via cAMP)
11.hypothyroidism
A SCHISM among the Axis during WWII":Addison diseaseSubacute thyroiditisCretinism/ Cold intolerance/ ConstipationHashimoto's diseaseInfectious-subacute thyroiditisSilent thyroiditisMyxedema coma
12.cushing synjdrome
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 122: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/122.jpg)
CUSHING:Central obesity/ Cervical fat pads/ Collagen fiber weakness/ Comedones (acne)Urinary free corisol and glucose increaseStriae/ Suppressed immunityHypercortisolism/ Hypertension/ Hyperglycemia/ HirsutismIatrogenic (Increased administration of corticosteroids)Noniatrogenic (Neoplasms)Glucose intolerance/ Growth retardation
13.addison disease
ADDISON:AutoimmuneDIC (meningcoccus)Destruction by cancer, infection, vascular insufficiencyIatrogenicSarcoidosis, granulomatous such as TB histiomycosishypOtension/ hypOnatermiaNelson's syndrome [post adrelectomy, increased ACTH]
14.Goiter
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 123: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/123.jpg)
GOITRE:GoitrogensOnset of pubertyIodine deficiencyThyrotoxicosis/ Tumor/ Thyroiditis [Hashimoto's]Reproduction [pregnancy]Enzyme deficiencies
15.dibetes complicatins
SHAKE:StrokeHeart attackAmputationsKidney diseaseEyes (vision loss)
16.steroid side effects
CUSHINGOID
Cataracts
Ulcers
Skin: striae, thinning, bruising
Hypertension/ Hirsutism/ Hyperglycemia
Infections
Necrosis, avascular necrosis of the femoral head
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 124: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/124.jpg)
Glycosuria
Osteoporosis, obesity
Immunosuppression
Diabetes
17.growth hormone toxicity
HE-SSP
Hyperglycemia
Edema
Scoliosis
Slipped capital femoral epiphysis
Pseudomotor cerebri
18.growth hormone toxicity in adults
PMA
Peripheral edema
Myalgia
Athralgia
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 125: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/125.jpg)
19.Follitropin alfa and Hcg toxicity
OMG-Humna Doing Exercise
Ovarian hyperstimulation
Multiple pregnencies
Gynecomestia in MEN
Headach
Deoression
Edema
20.amidarone side effects
6 P's:Prolongs action potential durationPhotosensitivityPigmentation of skinPeripheral neuropathyPulmonary alveolitis and fibrosisPeripheral conversion of T4 to T3 is inhibited -> hypothyroidism
21.oxytocin side effects
Hair-PUFF
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 126: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/126.jpg)
Hypotension
Placental abruption
Uterine rupture
Fetal distress
Fluid retension
22.prednisone –toxicity
BG-SMOAG
Behavioural changes
Glucose intolerance
Salt retension
Muscle wasting
Osteoprosis
Adrenal suppression
Growth Inhibition
23.Fludocortisoe-toxicity
CSS
Cogestive heart failure
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 127: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/127.jpg)
Salt and fluid retension
Symptoms of glucocorticoid
23.Tamoxifere-toxicity
THE
Thromboembolism
Hot flushes
Endometrial
24.Anastrozole-toxicity
A-ROAD-MATCH
Athralgia
Reduced bone mineral density
Osteoarthritis
Arthritis
Disk herniation
Musculoskeletal Disorders
Arthrosis
Cervical spondylosis
Hot flushes
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 128: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/128.jpg)
25.Prednisone –clinical applications
HOM
Hematalogic cancer
Organ transplantation
Many inflammatory conditions
26. Hormones that Increase Blood Glucose
"STENGG"
Somatotropin (growth hormone)Thyroid hormones (thyroxine and triiodothyronine)EpinephrineNorepinephrineGlucagonGlucocorticosteroids
27.PTU-mechanism
It inhibits PTU:Peroxidase/ Peripheral deiodinationTyrosine iodinationUnion (coupling)
28.steroid side effects
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 129: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/129.jpg)
BECLOMETHASONE:Buffalo humpEasy bruisingCataractsLarger appetiteObesityMoonfaceEuphoriaThin arms & legsHypertension/ HyperglycaemiaAvascular necrosis of femoral headSkin thinningOsteoporosisNegative nitrogen balanceEmotional liability
29.insulin mixing
"Not Ready, Ready Now":Air into NPHAir into RegularDraw up RegularDraw up NPH
30.coricosteroid side effects
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 130: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/130.jpg)
CUSHINGS BAD MD:CataractsUp all night (sleep disturbances)Suppression of HPA axisHypertension/ buffalo HumpInfectionsNecrosis (avascular)Gain weightStriaeBone loss (osteoporosis)AcneDiabetesMyopathy, moon facesDepression and emotional changes
GIT-Pharma
1. the PPIs
OLPER(milk )
Omeprazole
Lansoprazole
Pantoprazole
Rabeprazole
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 131: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/131.jpg)
Esomeprazole
2.types of laxatives
Types of laxatives
"Boss"
Bulk laxatives.Osmotic laxatives.Stimulant(irritant)laxatives.Stool Softeners.
Or "Bios"
Bulk laxatives.irritant(Stimulant)laxatives.Osmotic laxatives.Stool Softeners.
ASTHMA-PHARMA
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 132: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/132.jpg)
1.management of asthma
ASTHMA
AdrenergicsSteroidsTheophyllines)HydrationMask
2.asthma participating agents
DIPLOMAT:Drugs (aspirin, NSAIDs, beta blockers, etc)Infections (URTI/LRTI)Pollutants (at home, at work)Laughter(emotion)Oesophageal reflux (nocturnal asthma)MitesActivity and exerciseTemperature (cold)
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 133: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/133.jpg)
3. Asthma acute attack: 5 life threatening signs SHOCK:Silent chestHypotensionOne third of best/predicted PFRCyanosisKonfusion
4. Asthma: management of acute severe “O SHIT“:Oxygen (high dose: >60%)Salbutamol (5mg via oxygen-driven nebuliser)Hydrocortisone (or prednisolone)Ipratropium bromide (if life threatening)Theophylline (or preferably aminophylline-if life threatening
5. AAAA PPPP:Airway obstructionAnginaAnxietyAsthmaPneumoniaPneumothoraxPulmonary EdemaPulmonary Embolus
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 134: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/134.jpg)
NSAIDS-PHARMA
1. NSAIDs-classification:SOFIA PaBe..S-salicylateO-oxicame derivativesF-fenamic acid deriI-indol deriA-aryl acetic acid deriP-propionic acid deri-pyrrolo pyrrolo deri-pyrazolon deri-paramine phenol deriB-benzoxazocin deri
2. NSAIDs: contraindications
NSAID:N-ursing and pregnancyS-erious bleedingA-llergy/ Asthma/ AngioedemaI-mpaired renal functionD-rug (anticoagulant)
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 135: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/135.jpg)
Prostaglandin-pharma
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 136: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/136.jpg)
PROSTAGLANDINS confusion
A)All have "1 MISS"meansMISoprostol is PGE1.
B)cErviprimE has 2E socErviprimE is PGE2.
C)DInoproSTONEDI=2Remember that "stonE" in both(2) kidney n "stonE" has "E".So DINOPROSTONE is PGE2.
D)DINO mario has 2 FArari CAR.DINO-DINOPROST2 FArari-F2A [A for Alpha]CAR-CARBOPROSTsoDINOPROST n CARBOPROST r PGF2alpha
Note: DINOPROSTONE is PGE2 which is remember by 2 kidney stonE bt DINOPROST is PGF2alpha.
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 137: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/137.jpg)
By
ALI Zeeshan (QAMC)
ATHAR ALI (QAMC)NOREEN FATIMA(FJMC)
our group, page and blog
GROUP
https://www.facebook.com/groups/Medical.study.centre/
PAGEMe
dical
study ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 138: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/138.jpg)
https://www.facebook.com/pages/Medical-study-centre-session-2011-2016/1451699768417480
BLOG
http://atharali187.blogspot.com/
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 139: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/139.jpg)
4
.
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com
![Page 140: Medical Study Centre Session 2011-2016](https://reader031.vdocuments.net/reader031/viewer/2022020623/61f2347a808d806c0a732028/html5/thumbnails/140.jpg)
Medic
al stu
dy ce
ntre se
ssion 2011-2016
atharali187.blogspot.com