1

Volume 12, Issue 3

Fall 2014

INSIDE THIS ISSUE

Mountain Majesty, North East Tennessee .......2

The Mountain Majesty, cont .............................3

New Arrivals ......................................................4

Announcements ...............................................5

Publications ......................................................6

Abstracts ….. ...................................................7

Abstracts ...........................................................8

Abstracts, Grants, Recognition .......................9

Medicine in Touch

PO Box 70622

Johnson City TN 37614

Main Phone:

(423) 439-6282

Row 1 (bottom): Amrita Singh, Minni Meka, Allison Pierce, Ruchi, Bhavsar, Sridivya Parvataneni Neil Hamilton

Row 2: Pranay Parikh, Nene Ugoeke, Kalpit Devani, Mohsen Pourmorteza, Jacob Brazee Row 3: Christopher Cook, Sukumar Gandra, Manar Jbara, Tyler Dean, Jared Pack Row 4: Hasan Ahmad, Badar Siddiqui, Jordan Godbey, Fady Tawadros, Allen Elster, Calvin Green

Physicians in Touch

Spotlight

Our 1st Year Residents — 2014

Congratulations on completing your first 6 months!

**REMINDER**

FACULTY

MEETING

Internal Medicine

Conference

Room, Bldg. 1

at 4:45 p.m.

Dec. 9, 2014

Please mark your

calendars!

2

The Department of Internal Medicine is now the home to 12 of the

most beautiful photographs created by our own Kenton Hall. We

are fortunate to have access to his rich talent and eye behind the

camera. Take a moment when you visit our department to also

visit our gallery of North East Tennessee beauty.

Whenever I went hiking in the mountain empire, the walk was not

really that important to me. I wanted the big payoff at the end of

the hike; the beautiful view, a waterfall, or the unexpected treat……

and I wanted to take a picture of “it”. No matter how proficient a

photographer is, being at the right place at the right time with the

right light makes all the difference in how a photograph ultimately

ends up looking.

I think we live in a beautiful location; all you have to do is

take a short drive in any direction from Johnson City to see

sights that people all over the world travel long distances to

see.

The high country located along the Tennessee – North Caro-

lina border with elevations over 6000 feet gives us plants

usually found in Canada. The Rhododendron Gardens on

top of Roan Mountain produce a show stopping display eve-

ry June. Who would think you could have ski resorts in the

south? But the area around Banner Elk and Blowing Rock is

home to three ski resorts due to our elevation and altitude.

It just goes to prove that driving 30 to 60 minutes from

town will get you into a whole new ecosystem with different

weather patterns; diversity has been our greatest gift to both scientists and tourists.

The Great Smoky Mountain National Park is another region preserved because of the diversity of its flora and

fauna with every community interesting to explore

and photograph. Roaring Fork and Cataloochee are

my favorite areas within the Great Smoky Mountain

National Park; both have ample large mammals such

as bear, deer and elk plus preserved historical struc-

tures. The area encompassing Transylvania County,

south of the Great Smoky Mountain National Park in

North Carolina is known as the Land of Waterfalls.

Due to a drop in elevation of 2000 feet or more with-

in a couple of miles as the mountains drop to the

piedmont, the area contains a few waterfalls over

400 feet high such as Whitewater Falls (by compari-

son, Niagara Falls is 165 feet tall).

Roaring Fork, Great Smoky Mountain National Park

Rhododendron Gardens, Roan Mountain

Kenton Hall

The Mountain Majesty of North East Tennessee

3

Seeing 20 to 30 major falls in a day trip is possi-

ble. Nearly every turn on route 64 traveling

through Brevard, Cashiers, Highlands and Frank-

lin has a new vista or waterfall.

Connecting all these areas is one road that is our

national treasure, the Blue Ridge Parkway. Go

drive the

Blue Ridge;

you will

find that

you cannot

take a bad

picture.

I am honored that the department wanted to hang a dozen of my land-

scape photographs in our Building One offices. The photographs come

from all the places listed above; areas that I have used pretty much as a

playground since I got my driver’s license. Growing up in Boones Creek,

I just could not get over how many stunningly beautiful places existed

within an hour’s drive from home. All of the photos reflect easy day trips

from Johnson City, and I’ll be happy to provide guidance to anyone

wanting to see these locations in person.

Kenton Hall, Quillen College of Medicine, Internal Medicine

Kenton Hall is a graduate of Milligan College and started with the College of Medicine in 1981 working for Drs.

Katy Jane Mayberry-Carson, Donald Ferguson and Dwight Lambe in Microbiology. Kenton moved on to Internal

Medicine where he worked with Dr. Stephen Berk

on his Strongyloides project; “Clinical and Epide-

miologic Features of Strongyloidiasis - A Pro-

spective Study in Rural Tennessee”, JAMA Ar-

chives of Internal Medicine. After working in

clinical cytogenetics for a number of years Ken-

ton returned to research and working directly

with Drs. Kelly Smith and Guha Krishnaswamy.

Kenton feels fortunate to have worked with Dr.

David Chi in immunology until his retirement.

Currently part of the research team headed by

Dr. Charles Stuart, Kenton has 12 publications

and over 70 abstracts and poster presentations.

Kenton’s current position is Lab Manager for the

Internal Medicine Research Labs where with his

abundant experience ensures that our research

labs run safely and smoothly for our researchers.

Bass Lake, Moses Cone Estate, Blue Ridge Parkway

Whitewater Falls, Jocassee Georges

Blue Ridge Parkway Panorama, Rough Ridge

4

Weight: 6lbs. 14ozs Length: 19"

Parents: Leslie and Tommy Little

Brothers and sisters: Tristan, Jacob, Madalyn, Grace, Katie

THE NEWEST ADDITIONS TO OUR FAMILY

Omkar

Parents: Prakash and Dhara Chaudhari

August 23, 2014

5

Follow us on

Facebook!

ETSU Quillen College of

Medicine - Department of

Internal Medicine

Jack Ghably, MD presented by Leslie Fitzgerald, MD “Disseminated Strongyloidiasis Masquerading as Encephalopathy and

Failure to Wean from Mechanical Ventilation”

Aaysha Kapila, MD presented by Jennifer Phemister, MD

“A Not So Common Cause of GI Bleeding: Hemosuccus Pancreaticus”

Mehdi Pourmorteza, DO “Mysterious Intussusception in an Adult”

Mohsen Pourmorteza, MD

“A Case of Hyponatremia Potentiated by NSAIDS”

Charles Rives, MD

Ahmed Al-Sheyyab, MD

Mehdi Pourmorteza, DO

CONGRATULATIONS!

Tennessee ACP Conference

Franklin, Tennessee

Submission Winners - 2014 TN ACP Poster Contest

Medical Jeopardy Team Quillen—State Competition

Medicine in Touch

A quarterly publication

by the Department of

Internal Medicine,

Quillen College

of

Medicine

(423) 439-6282

etsu.edu/com/intmed

Oral Presentations

Jack Ghably, MD

Aaysha Kapila, MD

Mehdi Pourmorteza, DO

Mohsen Pourmorteza, MD

6

Notice: Publications listed are current as of 9/30/14 . Publications will not be included if: older than our cur-rent academic year, not listed in PubMed, submitted but not yet published. If you have publications and pub-lished/presented abstracts not listed in this or the last newsletter please submit those to heatonka@etsu.edu. These publications will be submitted to the Dean’s Office at the end of our academic year. All submissions should be in the National Library of Medicine (NLM) format.

JOURNAL ARTICLES

1. Inampudi C, Parvataneni S, Morgan CJ, Deedwania P, Fonarow GC, Sanders PW, Prabhu SD, Butler J, Forman DE, Aronow WS, et al. Spironolactone use and higher hospital read-mission for Medicare beneficiaries with heart failure, left ventricular ejection fraction <45%, and estimated glomerular filtration rate <45 ml/min/1.73 m(2.). Am.J.Cardiol. 2014 Jul 1;114(1):79-82.

2. Li CH, Xu F, Chow S, Feng L, Yin D, Ng TB, Chen Y. Hepatitis B virus X protein promotes hepatocellular carcinoma transformation through interleukin-6 activation of microRNA-21 expression. Eur.J.Cancer 2014 Oct;50(15):2560-9.

3. Li H, Hu D, Fan H, Zhang Y, LeSage GD, Caudle Y, Stuart C, Liu Z, Yin D. beta-Arrestin 2 Negatively Regulates Toll-like Receptor 4 (TLR4)-triggered Inflammatory Signaling via Targeting p38 MAPK and Interleukin 10. J.Biol.Chem. 2014 Aug 15;289(33):23075-85.

4. Liu X, Tsilimingras D, Paul TK. Prevalence and changes of untreated isolated systolic hy-pertension among non-Hispanic black adults in the United States. Hypertens.Res. 2014 Jul;37(7):685-91.

5. Mamudu HM, Paul TK, Veeranki SP, Budoff M. The effects of coronary artery calcium screening on behavioral modification, risk perception, and medication adherence among asymptomatic adults: A systematic review. Atherosclerosis 2014 Oct;236(2):338-50.

6. McClure C, Brudecki L, Ferguson DA, Yao ZQ, Moorman JP, McCall CE, El GM. MicroRNA 21 (miR-21) and miR-181b Couple with NFI-A To Generate Myeloid-Derived Suppressor Cells and Promote Immunosuppression in Late Sepsis. Infect.Immun. 2014 Sep;82(9):3816-25.

7. McGoldrick CA, Jiang YL, Brannon M, Krishnan K, Stone WL. In vitro evaluation of novel N-acetylalaninate prodrugs that selectively induce apoptosis in prostate cancer cells. BMC.Cancer 2014 Sep 18;14(1):675. PMCID: PMC4180535

8. Wang L, Yao ZQ, Moorman JP, Xu Y, Ning S. Gene Expression Profiling Identifies IRF4-Associated Molecular Signatures in Hematological Malignancies. PLoS.One. 2014;9(9):e106788.

9. Zhang Y, Wei L, Yu J, Li G, Zhang X, Wang A, He Y, Li H, Yin D. Targeting of the beta6 gene to suppress degradation of ECM via inactivation of the MAPK pathway in breast ade-nocarcinoma cells. Oncol.Rep. 2014 Aug 20. PMID: 25176506

10. Zhao J, Feng Y, Yan H, Chen Y, Wang J, Chua B, Stuart C, Yin D. beta-arrestin2/miR-155/GSK3beta regulates transition of 5'-azacytizine-induced Sca-1-positive cells to cardiomyo-cytes. J.Cell Mol.Med. 2014 Aug;18(8):1562-70.

Publications, Abstracts, Presentations, Grants, Awards

7

ABSTRACTS, POSTERS—Presented

1. Kapila A., Phemister J., Patel P., McKinney J., Murthy R.,Young M.F. A Not So Com-mon Cause Of GI Bleeding: Hemosuccus Pancreaticus. American College of Physicians, Franklin 2014

2. Kapila A., Chaudhari D., Khanna A., Goenka P. and Young M. F. (2014). Crouching Tiger, Hidden Dragon: Lung Adenocarcinoma Presenting as an Obstructive Jaundice. Poster presented at: American College of Gastroenterology; Philadelphia, PA.

3 Kapila A., Chhabra L., Patel P. and Young M. F. (2014). Post-Transplant Lymphoprolifer-ative Disorder with Diffuse Large B-Cell Lymphoma of the Stomach 14 Years Post Ortho-topic Heart Transplant. Poster presented at: American College of Gastroenterology; Phil-adelphia, PA.

4. Kapila A., Khanna A., Motiani R., Kalra A., Moorman J., Myers J. and Young M.F. (2014). Peritoneal Blastomycosis Mimicking Pseudo-Carcinomatosis. Poster presented at: Ameri-can College of Gastroenterology; Philadelphia, PA.

5. Kapila A., Khanna A., Tanios G., Young M. F. and Lesage G.D. (2014). Hepatocellular Cancer in a Non-cirrhotic Hepatitis C Patient. Poster presented at: American College of Gastroenterology; Philadelphia, PA.

6. Kapila A., Locke A., Khanna A., Patel P., Reddy C. and Young M. F. (2014). An Idiosyn-cratic Reaction of Clopidogrel. Poster presented at: American College of Gastroenterolo-gy; Philadelphia, PA.

7. Kapila A., Patel P. and Young M. F. (2014). Cholestatic Jaundice Due to Renal Cell Carci-noma: A Variant of Stauffer’s Syndrome. Poster presented at: American College of Gas-troenterology; Philadelphia, PA.

8. Kapila A., Patel P., Costello P.N. and Young M. F. (2014). Incidental Discovery of Hidden Carcinoid in a Meckel’s Diverticulum. Poster presented at: American College of Gastroen-terology; Philadelphia, PA.

9. Kapila A., Patel P., Costello P.N. and Young M. F. (2014). Painless Jaundice: A Rare Presentation of Primary Biliary Cirrhosis. Poster presented at: American College of Gas-troenterology; Philadelphia, PA.

10. Kapila A., Patel P., Ginn D. and Young M. F. (2014). A Case of Salmonella Typhi A Dysen-tery and Bacteremia in East Tennessee. Poster presented at: American College of Gastro-enterology; Philadelphia, PA.

11. Kapila A., Patel P., Murthy R. and Young M.F. (2014). Laxatives Can Paint Your Colon Black! Poster presented at: American College of Gastroenterology; Philadelphia, PA.

Publications, Abstracts, Presentations, Grants, Awards….cont.

8

ABSTRACTS, POSTERS Presented—Continued

12. Kapila A., Phemister J., Patel P., Murthy R., Reddy C. and Young M.F. (2014). An Inci-dental Discovery of Low Grade Appendiceal Mucinous Neoplasm. Poster presented at: American College of Gastroenterology; Philadelphia, PA.

13. Kapila A., Rives C., Barry N.G., Patel P. and Young M. F. (2014). Successful Treatment of Hypertriglyceridemia-Associated Pancreatitis with Insulin. Poster presented at: American College of Gastroenterology; Philadelphia, PA.

14. Ladia VM, Sitwala PS, Singh B, Ramu VK. ARVC: Classic Presentation of Silent Killer. Poster Presentation at American Medical Association Resident Fellow Symposium. Dallas Nov 2014

15. Mamudu HM, Paul TK, Veeranki SPV, Wang L, Liu X, Walker T, Budoff M. Predictors of coronary artery calcium and its relationship with traditional and behavioral risk factors for coronary artery disease among rural population. Society of Cardiovascular Computed Tomography. San Diego, CA. July 2014.

16. Pourmorteza, Mehdi, Pourmorteza, Mohsen, Brahmbhatt,P, Young MF, Ginn, D. Poster Oct. 2014. Presentation, American College of Physicians, Mysterious Intussusception in an Adult.

17. Phemister J., Kapila A., Patel A., Pierce D., Young M.F. (2014). Clostridium Septicum My-onecrosis killed Him before Colon cancer. Poster presented at: American College of Gas-troenterology; Philadelphia, PA.

18. Phemister J., Kapila A., Patel P., Borthwick T. and Young M. F. (2014). A Rare Case of an Isolated AL-Amyloid Polyp in the Colon. Poster presented at: American College of Gastro-enterology; Philadelphia, PA.

19. Phemister J., Kapila A., Patel P., McKinney J. and Young M.F. (2014). Glyburide induced Cholestatic hepatitis. Poster presented at: American College of Gastroenterology; Philadel-phia, PA.

21. Tanios, G, Jaishankar D, Mehta JB. Melanoma mimicking pulmonary arterio-venous mal-formation: Vasculognic mimicry. Poster presented at: ACP Franklin, TN October 9-10th, 2014

ABSTRACTS

Presented and Published

1. Inampudi C., Parvataneni S., Morgan C., Deedwania P., Fonarow G., Prabhu S, Butler J., Aronow W., Sanders P., Allman R., Ahmed A. Chronic Kidney Disease and Higher Risk of 30-Day All-Cause Readmissions in Heart Failure: Findings from a Propensity-Matched Study, Journal of Cardiac Failure, Volume 20, Issue 8, Supplement, Page S56, August 2014

Publications, Grants, Awards, Presentations….cont.

9

ABSTRACTS, Presented and Published—Continued

2. Inampudi C., Parvataneni S., Morgan C., Deedwania P., Fonarow G., Prabhu S, Butler J., Zile M., Aronow W., Sanders P., Allman M., Ahmed A. Lack of Association Between Spironolactone Use and 30-Day All-Cause Readmission In Hospitalized Medicare Benefi-ciaries With Systolic Heart Failure Eligible for Spironolactone Therapy, Journal of Cardiac Failure, Volume 20, Issue 8, Supplement, Page S58, August 2014

3. Nour SA, Nour HA, Mehta J, Roy T, Byrd R. Tracheobronchial calcification due to warfa-rin therapy. Am.J.Respir.Crit Care Med. 2014 Jun 15;189(12):e73.

GRANTS

1. NIH R-15 (three years). A novel prodrug to treat melanoma. Total requested $ 438,000. PI- Dr. William Stone, Co-investigator: Dr. K. Krishnan MD

2. Department of Defense (DOD). Oxidized protein hydrolase (OPH) as a prostate cancer drug target. Total requested $108,000. PI- Dr. William Stone, Co-Investigator: Dr. K. Krishnan MD

AWARDS, RECOGNITION and ANNOUNCEMENTS

Dr. Koyamangalath Krishnan has been selected to serve as Academic Editor on the Edito-rial Board of PLoS One for a three year term.

Dr. Stephen Geraci has been selected as Vice Chair of the Communications Committee for AAIM

Publications, Grants, Awards, Presentations….cont.