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meta-analysis icu intensive insulin

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Meta-Analysis ICU Intensive Insulin Includes NICE-SUGAR 90 day mortality—no overall effect (pooled RR 0.93) – 26 trials (n=13,567) ↑ Risk hypoglycemia (RR 6.0) – 14 trials (n=12,347) Benefit surgical ICUs (RR 0.63) – 5 trials (n=1,972) – Majority VBG SICU study No benefit medical/mixed ICUs (RR 1.00) Griesdale et al., Can Med Assoc J. 2009;180:821

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Meta-Analysis ICU Intensive Insulin. Includes NICE-SUGAR 90 day mortality—no overall effect (pooled RR 0.93) 26 trials (n=13,567) ↑ Risk hypoglycemia ( RR 6.0) 14 trials (n=12,347) Benefit surgical ICUs (RR 0.63) 5 trials ( n=1,972 ) Majority VBG SICU study - PowerPoint PPT Presentation

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Page 1: Meta-Analysis ICU Intensive Insulin

Meta-Analysis ICU Intensive Insulin

Includes NICE-SUGAR 90 day mortality—no overall effect (pooled

RR 0.93)– 26 trials (n=13,567)

↑ Risk hypoglycemia (RR 6.0) – 14 trials (n=12,347)

Benefit surgical ICUs (RR 0.63)– 5 trials (n=1,972)– Majority VBG SICU study

No benefit medical/mixed ICUs (RR 1.00)

Griesdale et al., Can Med Assoc J. 2009;180:821

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