modeling platform for collaboration zheng li
DESCRIPTION
Modeling Platform for Collaboration Zheng Li. TERANODE Modeling Platform. TERANODE Design Suite Biological Modeler Protocol Modeler Protocol Player Closed-loop Edition Starter Edition (free) TERANODE Model Server SDK. Teranode History. 2005. Q1. V2.5 Launch (Jan). Q4. - PowerPoint PPT PresentationTRANSCRIPT
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Modeling Platform for CollaborationZheng Li
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TERANODE Modeling Platform
• TERANODE Design
Suite– Biological Modeler
– Protocol Modeler
– Protocol Player
– Closed-loop Edition
– Starter Edition (free)
• TERANODE Model
Server
• SDK
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Teranode History
Incorporated in Seattle, WA (June)DARPA, NSF, NIH, Intel research funding
Technology Transfer Complete
NIH Grant Awarded ($1.8M over 3yrs)3 Teranode Patents Pending
Closed Series A Production Clients V1 Released (Feb)
First Production Sites
V2 Launch (Oct)“ Top 100 Innovators” award2004
2003
Q4Q4Q4Q4
Q3Q3Q3Q3
Q1Q1Q1Q1
Q2Q2Q2Q2
Q4Q4Q4Q4
Q3Q3Q3Q3 Signed First Pilot Customer
2005
Q1Q1Q1Q1
Q2Q2Q2Q2
Q4Q4Q4Q4
Q3Q3Q3Q3
V2.5 Launch (Jan)
Q1Q1Q1Q1
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The Challenge
• Closed-loop R&D requires • flexibility and Scalability
Flexibility Scalability
DocumentsDesktop apps
DatabasesCustom apps
Existing options force users and managers
to choose
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Our Approach
Modeling provides both
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Informatics Choices:Databases, Documents, and Models
DynamicStatic
1,000’s ofData Points
Millions ofData Points
DATA REQUIREMENTS
SCALE
Documents
Error-proneTime-consumingLimited Reuse
LIMS/DatabasesExpensive ProgrammingLong Deployment Cycles
Poor Data Mobility
ModelsProgramming-free
Common Data PlatformData MobilityCost-effective
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Analytics
Lab Equipmentand Systems
System BiologyRepositories
SampleManagement
PathwayAnalytics
ReagentProduction
TERANODESolutions
TERANODE Offering
TERANODEDesign Suite
TERANODEModel Server
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Data Bottlenecks with Current LIMS
Delayed ResultsFragmentation
Data Must Be Imported and ExportedBetween Multiple Systems and Applications
Bottleneck Impact
Slow and CostlyDevelopment
ProgrammingChanging Data Requirements ofProtocols Requires Programming
LimitedCollaboration
CentralizationData Access and Sharing Requires
Database Connection
Siloed SystemsRigidity
Required Schema StandardizationLimits Broad Deployments
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Model-Driven LIMS with Teranode
Real-TimeDecision Support
Protocol ModelsAutomation of Data Management,
Integration, and Analytics
Solution Benefit
RapidDevelopment
Protocol ModelerVisual Protocol Designs by Scientists
Captured as Models
Common PlatformProtocol PlayerDesign Independent Automation
AnywhereData Usage
VLXPortable Data Format Enabling Data
Mobility for Collaboration and Integration
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TERANODE Solution Screening Automation
• TERANODE Screening Automation– TERANODE Design Suite– TERANODE Model Server– Screening Models– Integration Libraries
• Benefit– Flexible assay design – Data automation– Real-time decision support– No programming required
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Challenge
Flexible Assay Design
Solution
Results
• Deployed solution in 7 days
• Provided unlimited assay design flexibility
• Automated statistical & regression analysis
• Enhanced project team collaboration
Develop a protein array solution that supports changing assay parameters and automates statistical and regression analysis
• TERANODE Design Suite
• Custom regression analysis tool
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Challenge
Data Automation
Solution
Results
• Deployed solution in 5 days
• Automated data processing and analysis
• Eliminated data processing errors
• Provided real-time assay results
Develop a chemical screening solution that automates data processing and IC50 determinations
• TERANODE Design Suite & Model Server
• MD Spectramax data importer tool
• Data dictionary
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Data ServicesData Flow, Storage, and Indexing
Model-Driven Informatics:VLX Models
VLX Model
Computation ServicesAnalytics and Simulations
Integration ServicesInterchange with Equipment and
External Systems
Compliance ServicesAudit Trail and Reporting
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SampleSampleMgmt.Mgmt.DiagnosticsDiagnostics
TargetTargetId.Id.
HTSHTSHitHit
TriageTriage
ProcessProcessScienceScience
AssayAssayDesignDesign
StudyStudyDesignDesign
PathwayPathwayAnalyticsAnalytics
ReagentReagentProd.Prod.
Versatility of TERANODE Platform
ReagentReagentProd.Prod.
PathwayPathwayAnalyticsAnalytics
HTSHTS
SampleSampleMgmt.Mgmt.
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Demo