mosby items and derived items © 2006 by mosby, inc. slide 1 chapter 4 proteins ahmad adeeb
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Mosby items and derived items © 2006 by Mosby, Inc. Slide 1
Chapter 4 Chapter 4 Proteins
Ahmad Adeeb
Mosby items and derived items © 2006 by Mosby, Inc. Slide 3
Key ConceptsKey Concepts
• Food proteins provide the amino acids necessary for building and maintaining body tissue.
• Protein balance, both within the body and in the diet, is essential to life and health.
• The quality of a protein food, and its ability to meet the body’s needs, is determined by the composition of amino acids.
Mosby items and derived items © 2006 by Mosby, Inc. Slide 4
Amino Acids: Basic Building Amino Acids: Basic Building MaterialMaterial
• Each protein is made up of hundreds of amino acids
• Amino acids form unique chain sequences to form specific proteins
• When protein foods are eaten, proteins are broken down into amino acids
• Amino acids are reassembled in the body to form a variety of proteins
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Classes of Amino AcidsClasses of Amino Acids
1-Indispensable amino acids “ عنه غنى ”ال Body cannot synthesize
2-Dispensable amino acids“ اساسي “غير Body can synthesize
***Conditionally indispensable amino acids Normally synthesized but some health
conditions may require dietary intake
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A Healthy BalanceA Healthy Balance
• Protein balance Catabolism: breakdown Anabolism: resynthesis
• Nitrogen balance Positive nitrogen balance: body stores more
than it excretes Negative nitrogen balance: body takes in less
than it excretes
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Functions of ProteinFunctions of Protein
• Tissue building
• Energy
• Water balance
• Metabolism
• Body defense system
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Notes Notes
• Food proteins provide the amino acids necessary for building and maintaining body tissue.
• Protein balance, both within the body and in the diet, is essential to life and health.
• The quality of a protein food, and its ability to meet the body’s needs, is determined by the composition of amino acids.
Mosby items and derived items © 2006 by Mosby, Inc. Slide 9
Food Sources of ProteinFood Sources of Protein
• Complete proteins Meat Soy
• Incomplete proteins Plant-origin foods• Grains حبوب
• Legumes النبات قرون• Nuts
• Seedsبذور• Fruits and vegetables
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Vegetarian DietsVegetarian Diets
• Must combine foods to cover all amino acid needs
• Health benefits & risk
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Digestion of ProteinsDigestion of Proteins
• Mouth
• Stomach: enzymatic breakdown of protein by proenzymes (zymogens) Pepsin Hydrochloric acid Rennin ” in child”
• Small intestine Pancreatic secretions Intestinal secretions
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Body Needs for ProteinBody Needs for Protein
• Tissue growth needs
• Dietary protein quality Chemical score (CS) Biological value (BV)
• Additional needs due to disease
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Dietary Deficiency or ExcessDietary Deficiency or Excess
• Protein-energy malnutrition Kwashiorkor Marasmus
• Excess protein Usually means excess fat intake also Protein displaces other healthy foods in diet Kidneys stressed Potential calcium loss
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Dietary GuidesDietary Guides
• Recommended Dietary Allowances (RDAs) Relate to age, sex, weight
• Dietary Reference Intakes (DRI) from National Academy of Sciences 10% to 35% of total caloric intake from protein
(children and adults)
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Protein NeedsProtein Needs
• Assumes individual consumes 2200 kcal per day; based on recommendation of 10% to 35% of total kcalories from protein
• 2200 kcal x 0.10 – 0.35 = 220 – 770 kcal per day from protein
• 220 – 770 kcal 4 kcal/g = 55 – 192.5g of protein per day