multi-species assays€¦ · 2 3 table of contents our company p. 3 to contact us p. 4 allergy p. 5...

MULTI-SPECIES ASSAYS

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TABLE OF CONTENTSOur Company p. 3

To contact us p. 4

Allergy p. 5

Endocrinology & Metabolism: p. 6

Species specific ASSAYS

DIAsource human ELISA tested on animals samples

Infectious disease p. 9

Endocrinology & Metabolism : p. 10

DIAsource human RIA tested on animals samples

Custom Diagnostic Laboratory services & Sales Conditions p. 12

Available Assays - Summary p. 14

ELISA , ANTIBODIES

& INSTRUMENTS

by

VITAMIN Dby

RIAby

YOUR SPECIALIST IN

ENDOCRINOLOGY

by

ELISA , ANTIBODIES

& INSTRUMENTS

by

VITAMIN Dby

RIAby

YOUR SPECIALIST IN

ENDOCRINOLOGY

by Eric MaesBusiness Segment Manager ELISA, Instruments & Antibodies DIAsource ImmunoAssays S.A.

OUR COMPANY 30 YEARS OF EXPERIENCE IN IVD (KITS AND INSTRUMENTATION)

DIAsource ImmunoAssays S.A. (a Biovendor group company), an international diagnostic company (Belgium), develops, manufactures and markets clinical diagnostic products in the field of endocrinology and infectious diseases. Core products are based on RIA - and ELISA technology and also include reagents to be ran on open ELISA automated analysers as well as antibodies for use in in-vitro diagnostic assays. DIAsource has specific development - and manufacturing programs for Vitamin D, Renin, Calcitonin and many other parameters. We also provide selected instrumentation : we offer ELISA reader, - washer and - shaker, along with open and closed fully automated ELISA platforms helping our customers to automate their tests. It is our ambition to use our 30 years of expertise in Antibody - and Assay development to remain a well-known company of diagnostic immunoassays and instrumentation for the IVD market.

MISSIONOur mission is to develop, manufacture and market a complete panel of quality immunoassays and instrumentation as accurate, reliable, diagnostic tools to detect and monitor endocrine disorders and infectious diseases. We are dedicated to provide high quality assays and instrumentation to deliver uncompromising support to our customers. We strive to meet our customers needs through a long-term professional relationship and by offering a real added value. Our company is driven by commitment

to quality of products and services.

MUTI-SPECIES PRODUCT RANGEDIAsource ImmunoAssays S.A. provides a variety of specific ELISA for animal science research to be used either in the field of the Infection Diseases for the detection of specific antigens or antibodies due to bacterial or viral infections, either in the field of Endocrinology.

Moreover, we also took the opportunity to include the information we received from customers relative to the use of our human dedicated assays (ELISA, IRMA, RIA) with multi-species samples from bird, fish, monkey, porcine,…. Please note that these cross-reactions have not been verified or tested by DIAsource ImmunoAssays S.A. but will be an useful support for the end-user.

COMMITMENT TO QUALITYWe believe that the quality of products and services finds its origin in scientific expertise, good organization of all operational activities and in well-structured decision processes. These principles are laid out in our ISO 13485:2003 quality manual. Through the integration of product quality in our development - and manufacturing processes and a specific customer-oriented approach, we have directed our quality system to comply with the harmonized standard for quality systems within the context of the European Directive for In Vitro Diagnostics. Our internal quality management system is designed to pursue a continuous improvement of our customer service, our product quality and the efficiency of our operations. All our kits and instruments for in-vitro diagnostics (IVD) carry the CE mark and comply with IVD Directive requirements.

Beatrice de BormanCEODIAsource ImmunoAssays S.A.

Peter KerckxInternational Sales Director & Business Segment Manager RIA DIAsource ImmunoAssays S.A.

Jan WautersSales- & Business Development Manager Vitamin D DIAsource ImmunoAssays S.A.

5 4

ALLERGY SPECIES SPECIFIC ELISA*

Product name Cat# Label Size Sample type Sample size (µL)

Control Levels

RangeIncubation

(hours)

Max shelf life (weeks)

Remarks

Canine

Food 16 Screen IgG ILE-SCH21 HRP 96 T S - EP - HP 2 2 0 - 50 U/ml ON 48 5 samples x 16 antigens

Food 16 Screen IgE ILE-SCH20 HRP 96 T S - EP - HP 250 2 0 - 50 U/ml ON 48 5 samples x 16 antigens

Cat

Food 16 Screen IgG ILE-SCK21 HRP 96 T S - EP - HP 10 2 0 - 50 U/ml ON 48 5 samples x 16 antigens

Food 16 Screen IgE ILE-SCK20 HRP 96 T S - EP - HP 250 2 0 - 50 U/ml ON 48 5 samples x 16 antigens

Horse

Feed 8 Screen IgE ILE-SCP20 HRP 96 T S - EP - HP 1000 2 0 - 50 U/ml ON 48 10 samples x 8 antigens

Feed 8 Screen IgG ILE-SCP24 HRP 96 T S - EP - HP 5 2 0 - 50 U/ml ON 48 10 samples x 8 antigens

Perennial 16 Screen IgE ILE-SCP21 HRP 96 T S - EP - HP 1000 2 0 - 50 U/ml ON 48 5 samples x 16 antigens

Seasonal 16 Screen IgE ILE-SCP22 HRP 96 T S - EP - HP 1000 2 0 - 50 U/ml ON 48 5 samples x 16 antigens

Insects 7 Screen IgE ILE-SCP23 HRP 96 T S - EP - HP 1000 2 0 - 50 U/ml ON 48 10 samples x 7 antigens

*Assays specially developped to be used on animal samples EP=EDTA Plasma - HP=Heparin Plasma - S=Serum

TO CONTACT US Our people, our professional and experienced Customer Service and Technical Support teams are dedicated to ensure complete customer satisfaction. We take pride in providing helpful and accurate information in a 24-hour turnaround time.Ordering : please see below and consult the ‘How to order’ section for your local contact.

SHIPPING SURPERVISOR

Luciana FrassonTel. : +32 (0)10 84 99 69 Fax : +32 (0)10 84 99 95 [email protected]

Customer & Supplier ManagerNathalie DierickxTel. : +32 (0)10 84 99 16 [email protected]

TECHNICAL SUPPORT SPECIALIST

Valérie Preud’hommeTel. : +32 (0)10 84 99 [email protected]

Aurélie BernardTel. : +32 (0)10 84 99 [email protected]

REGULATORY AFFAIRS COORDINATOR

SERVICE ENGINEER- INSTRUMENTS

Albert Rosell Tel. : +32 (0)10 84 99 76 [email protected]

Isabelle DehartTel. : +32 (0)10 84 99 04 Fax :: +32 (0)10 84 99 94 [email protected]

PRODUCT DEVELOPMENT, QUALITY & REGULATORY AFFAIRS MANAGER

SALES & MARKETING International Sales Director & Business Segment Manager RIAPeter KerckxMobile : +32 (0)475 57 76 86 [email protected]

Business Segment ManagerELISA & Instrumentation and AntibodiesEric MaesMobile : +32 (0)479 70 00 71 [email protected]

Sales- and Business Development Manager Vitamin DJan WautersMobile: +32 (0)479 94 34 78 [email protected]

Sales Director for Spain & Export Manager LatAmAlberto RosellMobile SP : +34 696 271 518 Fax SP : +34 934 107 866 [email protected]

Sales Manager LatinoamericaOlga Lucia Guayacan Mobile : +57 31 030 390 03 [email protected]

Product ManagerDavid DegelsTel. : +32 (0)10 84 99 05 [email protected]

CUSTOMER SERVICE - ORDERINGTel. : +32 (0)10 84 99 00 - Fax : +32 (0)10 84 99 90-96 - [email protected] Free Phone : 0800 159 59 - France Free Phone: 0800 908 443 - France Free Fax : 0800 902 588

Sales Manager France & District Manager WalloniaLaurent AugisTel. : +32 (0)479 70 00 72 Mobile : +33 6 85 60 17 [email protected]

Marketing Project CoordinatorJoëlle BockTel. : +32 (0)10 84 99 13 [email protected]

Commercial delegateChristophe GagnepainTel. : +34 934 107 866 Mobile : +34 697 229 227 [email protected]

Product Manager & Principal Scientist Vitamin DNicolas HeureuxTel. : +32 (0)10 84 99 40 [email protected]

Customer Service ManagerMuriel Hirsoux

CustomerService Representative

Sabrina Baio Isabelle Rosman

M-F Sanchez

CEOBéatrice de Borman

Tel. : +32 (0) 10 84 99 [email protected]

7 6

ENDOCRINOLOGY & METABOLISM

SPECIES SPECIFIC ASSAYS*

Product name Cat# Label SizeSample

type Sample size (µL)

Range Sensitivity Incubation

(hours)Remarks

Bovine

Albumin ELISA RSHAKRBS018R HRP 96 TS - EP - HP - CP - CCS

100 0,78-50 ng/ml 39 pg/ml 2,5 RUO

Canine

Clusterin ELISA RD491034200R BIOT 96 T S - U 5 / 50 4-128 ng/ml 0,2 ng/ml 3,5 RUO / C.R. with cat

hsCRP ELISA RH931CRP01DCR HRP 96 T S 5 1,5 - 40 µg/ml 3,6 ng/ml 1,2 RUO

Cystatin C ELISA RD491009100R HRP 96 T S - U 5 0,31 - 10 ng/ml 0,005 ng/ml 3 RUO

Ghrelin Acylated ELISA RA494062500R AChE 96 T P 20 2 - 250 pg/ml 2 pg/ml ON RUO

Insulin ELISA R S H A K R I N 0 1 2 T R BIOT 96 TS - EP - HP

- CP10 188 - 12 000 pg/ml 13 pg/ml 3 RUO

Procalcitonin ELISA RD491488200R BIOT 96 T S - U 20 12,5 - 800 pg/ml 3,6 pg/ml 3,5 RUO

Prolactin ELISA RTC022R HRP 96 T S 25 2,5 - 80 ng/ml 0,4 ng/ml 3,5 RUO

TSH ELISA RTC019R HRP 96 T S - P 100 0,2 - 5,2 ng/ml 0,01 ng/ml 2,5 RUO

Uromodulin ELISA RD491163200R BIOT 96 T S - U 5 0,16 - 10 ng/ml 0,01 ng/ml 3,5 RUO

*Assays specially developped to be used on animal samplesCCS=Cell Culture Supernatant - CP=Citrate Plasma - EP=EDTA Plasma - HP=Heparin Plasma - P=Plasma - S=Serum - U=Urine




(hours)Remarks

Monkey

sICAM-1 ELISA RAF103R HRP 96 T S - CCS 25 6,25 - 100 U/ml 1,05 U/ml 1,2 RUO

Interleukin-10 ELISA RAF029R BIOT 96 T S - CCS 50 3,9 - 50 U/ml 1,3 U/ml 3,2 RUO

Interleukin-12 (p70) ELISA

RAF032R BIOT 96 T S - CCS 50 3,9 - 250 U/ml 1,6 U/ml 3,2 RUO

Interleukin-2 ELISA RAF055R BIOT 96 TS - EP -HP - CP - CCS

50 18,8 - 1200 pg/ml 9,1 pg/ml 3,5 RUO



sPECAM-1 ELISA RAF110R HRP 96 T S - CCS 10 0,48 - 30 U/ml 0,06 U/ml 3,2 RUO

sP-Selectin ELISA RAF112R HRP 96 T S - CCS 10 0,8 - 50 U/ml 1,3 U/ml 2,5 RUO

TNF-alpha ELISA RAF099R HRP 96 T S - CCS 20 0,94 - 60 U/ml 0,39 U/ml 2,2 RUO

sTNF-R I ELISA RAF116R HRP 96 T S - CCS 10 0,09 - 6 U/ml 0,05 U/ml 2,2 RUO

sVE-Cadherin ELISA RAF120R BIOT 96 T S - CCS 50 0,19 - 12,5 U/ml 0,10 U/ml 3,2 RUO

Porcine

Ghrelin Acylated ELISA RA594062400R AChE 96 T EP 50 3,9 - 500 pg/ml 10 pg/ml ON RUO

Ghrelin Unacylated ELISA

RA594063400R AChE 96 T EP 20 3,9 - 500 pg/ml 5 pg/ml ON RUO

IFN-alpha 1 ELISA RA19016R HRP 96 T 100 0,08 - 10 ng/ml ≤ 0,08 ng/ml RUO

IFN-gamma 1 ELISA RA19017R HRP 96 T 100 0,08 - 10 ng/ml ≤ 0,08 ng/ml RUO

Insulin ELISA RSHAKRIN013TR BIOT 96 T S - P - CCS 10 188 - 12000 pg/ml 13 pg/ml 3 RUO

Interleukin-10 ELISA RA19020R HRP 96 T 100 0,08 - 10 ng/ml ≤ 0,16ng/ml RUO

Interleukin-6 ELISA RA19019R HRP 96 T 100 0,08 - 10 ng/ml ≤ 0,08 ng/ml RUO

TNF-alpha ELISA RA19018R HRP 96 T 100 0,02 - 20 ng/ml ≤ 0,02 ng/ml RUO

Interleukin-18 ELISA RAF044R BIOT 96 T S - CCS 50 39,1 - 2500 pg/ml 23 pg/ml 3,2 RUO

CCS=Cell Culture Supernatant - CP=Citrate Plasma - EP=EDTA Plasma - HP=Heparin Plasma - P=Plasma - S=Serum - U=Urine

9 8

DIASOURCE HUMAN ELISA TESTED ON ANIMALS SAMPLES



Control Levels


(hours)


Source

Rat

Rat 25OH Vitamin D Total ELISA

KRR1971 HRP 96 T S 50On

request0 - 135 ng/ml 2,8 ng/ml 2,75 130 Instruction for use

Monkey

Cpep II Elisa KAP0401 HRP 96 T S 100 2 0,05 - 4,9pmol/ml 0,01pmol/ml 2,5 32 Instruction for use

IFNgamma Elisa KAP1231 HRP 96 T S 50 2 1 - 30IU/ml 0,03IU/ml 2,25 60End-user

communication

IL-1Beta KAP1211 HRP 96 T S 200 2 24 - 1166 pg/ml 0,35 pg/ml 2,25 60End-user

communication

IL-6 Elisa KAP1261 HRP 96 T S 100 2 23,3 - 2560 pg/ml 2 pg/ml 2,25 60End-user

communication

IL-6 Elisa KAP1261 HRP 96 T S 100 2 23,3 - 2560 pg/ml 2 pg/ml 2,25 60

Lozier et al. (1999) Blood 94(12):3968-3975; Shean et al.

(2000) Human Gene Therapy 11:1047-1053

IL-8 Elisa KAP1301 HRP 96 T S 100 2 40 - 1845 pg/ml 1,1 pg/ml 2,5 60End-user

communication

IL-8 Elisa KAP1301 HRP 96 T S 100 2 40 - 1845 pg/ml 1,1 pg/ml 2,5 60Shean et al. (2000)

Human Gene Therapy 11:1047-1053

IL-10 Elisa KAP1321 HRP 96 T S 100 2 11 - 1335 pg/ml 1 pg/ml 4,5 60End-user

communication

TNFalpha Elisa KAP1751 HRP 96 T S 200 2 7 - 518 pg/ml 0,07pg/ml 4,5 60End-user

communication

Mouse

1,25(OH)2 Vit D ELISA

KAP1921 HRP 96 T S 500 2 0 - 190 pg/ml 0,8 pg/ml 19 52End-user

communication

Bovine

Insulin Elisa KAP1251 HRP 96 T S 50 2 5 - 250µIU/ml 0,17µIU/ml 0,75 60 Instruction for use

Porcine


Canine


S=Serum

INFECTIOUS DISEASE SPECIES SPECIFIC ELISA*



Quali / Quanti

Incubation (hours)


Infectious Disease Remarks

All vertebrates (except mice)

TBEV Ig ELISA TBE096 HRP 96 T S - CP 50 Quali 2,5 15Tick borne encephalitis for mammal animals)

CE - IVD

Bovine

BHV-1 Ab ELISA BHd480 HRP 480 T S - Milk 10 Quali 2 15Infectious bovine rhi-

notracheitis - IBRGMP

IBR-gB ELISA IBR192 HRP 192 T S - P - Milk 50 / 100 Quali 3,5 12Infectious bovine

rhinotracheitis - detection of gB Ab

GMP

BVD-MD Ab ELISA BVD480 HRP 480 T S 10 Quali 2 24Bovine Viral Diarrhoea -

Mucosal DiseaseGMP

EBLV Ab ELISA EBL480 HRP 480 T S 10 Quali 2,5 12 Enzootic bovine leukosis GMP

Canine

Dog Borrelia IgM/IgM ELISA

DBGM96 HRP 96 T S 5 Quali 1,5 24 Tick borne encephalitis GMP

Fish

IPNV Ag ELISA IPN096 96 T CCS - TH 50 Quali 2,5 18Infectious pancreatic necrosis of salmonds

GMP

SVCV Ag ELISA SVC096 96 T CCS - TH 50 Quali 2,5 18 Spring viraemia of carps GMP

VHSV Ag ELISA VHS096 96 T CCS - TH 50 Quali 4 18Viral haemorrhagic septi-

caemia of salmondsGMP

Porcine

AD Ab ELISA AD0480 480 T S - TH 10 Quali 1,5 24 Aujeszky s disease GMP

*Assays specially developped to be used on animal samplesCCS=Cell Culture Supernatant - CP=Citrate Plasma - P=Plasma - S=Serum - TH=Tissue Homogenate

11 10

ENDOCRINOLOGY & METABOLISM

DIASOURCE HUMAN RIA TESTED ON ANIMALS SAMPLES

P=Plasma - Sa=Saliva - S=Serum - U=Urine



Control Levels


(hours)


Source

Gastropod

1.25(OH)2 Vit D RIA KIP1929 125I 48 T S - P 500 2 0 - 400 pg/ml 1,4 pg/ml ON 10

Journal of Shellfish Research - MAI K. (2007) Interaction

between vitamins A and D on growth and

metabolic responses of abalone Haliotis discus

hannai

Rat

ACTH IRMA KIP0061 125I 96 T EP 200 2 9,6 - 1932 pg/ml 1,16 pg/ml 3 7Instruction for use

( C.R.:39%)

Canine

CORTISOL-RIA-CT KIPI28000 125I 96 TS - P - U

Sa25

2002

17 - 450 µg/L 0,9 - 45 µg/L

0,9 µg/L 0,53 µg/L

0,75 2

12End-user

communication

PROG-RIA-CT KIP1458 125I 96 T S 50 2 0,23 - 40 ng/ml 0,05 ng/ml 2 10End-user

communication

Insulin IRMA KIP1251 125I 96 T P 50 2 5,7 - 440 µIU/ml 1 µIU/ml 2 10 Instruction for use

T4-RIA-CT KIP1641 125I 96 T S 20 2 12,8 - 500 nmol/L < 5 nmol/L 1 10End-user

communication

E2-RIA-CT KIP0629 125I 96 T S 50 2 9 - 3900 pg/ml 2,7 pg/ml 3 10End-user

communication

Testo-RIA-CT KIP1709 125I 96 T S 50 2 0,11 - 16,4 ng/ml 0,05 ng/ml 3 10End-user

communication



Control Levels


(hours)


Source

Cat

Insulin IRMA KIP1251 125I 96 T P 50 2 5,7 - 440 µIU/ml 1 µIU/ml 2 10End-user

communication

E2-RIA-CT KIP0629 125I 96 T S 50 2 9 - 3900 pg/ml 2,7 pg/ml 3 10End-user

communication

Testo-RIA-CT KIP1709 125I 96 T S 50 2 0,11 - 16,4 ng/ml 0,05 ng/ml 3 10End-user

communication


Sa25

2002

17 - 450 µg/L 0,9 - 45 µg/L

0,9 µg/L 0,53 µg/L

0,75 2

12End-user

communication

Horse


Sa25

2002

17 - 450 µg/L 0,9 - 45 µg/L

0,9 µg/L 0,53 µg/L

0,75 2

12End-user

communication


communication

T3-RIA-CT KIP1631 125I 96 T S 50 2 0,35 - 14 nmol/L 0,1 nmol/L 1 10End-user

communication

Bird


Sa25

2002

17 - 450 µg/L 0,9 - 45 µg/L

0,9 µg/L 0,53 µg/L

0,75 2

12End-user

communication

Bovine



communication

Porcine


PROG-RIA-CT KIP1458 125I 96 T S 50 2 0,23 - 40 ng/ml 0,05 ng/ml 2 10

Polish Journal of Veterinary Sciences

Vol. 16, No. 2 (2013), 323–332

Mouse

RIAZENco Aldosterone

R-CW-100 125I 100 T S- U 200 - 5 2 25 - 1500 pg/ml 1,4 pg/ml ON or 3 8End-user

communication

EP=EDTA Plasma - P=Plasma - Sa=Saliva - S=Serum - U=Urine

13 12

CUSTOM DIAGNOSTIC LABORATORY SERVICES & SALES CONDITIONS

ISO 9001 AND ISO 13485 APPROVED The scientists at DIAsource mmunoAssays S.A have extensive experience in the development of antibodies and related enzymatic or radioactive assays. They can help guide you through each step in the process of purifying, fragmenting, coating and labeling antibodies. High level technicians can be consulted at any time to discuss other services like filling and freeze-drying. We can offer specific and flexible suggestions to enhance the performance of your final product. All services are manufactured under strict ISO-9001 guidelines.

SERVICES AVAILABLE Coating services

• Coating of polystyrene tubes individually capped : batch size from 30,000 up to 100,000 tubes with your antibodies according to your coating procedure

• Coating of microtiter plates in sealed aluminum bags with your antibodies according to your coating procedure : batch size from 150 up to 900 microtiter plates

• Primary coated tubes with anti-rabbit, anti-sheep or avidin-streptavidin for RIA-IRMA applications

• Primary microtiter plates with anti-rabbit, anti-sheep, or avidin-streptavidin for ELISA applications

Filling services

• From solution preparation to filling, capping and labeling.

Freeze-drying services

• Freeze-dry from 0.25ml up to 15ml in glass vials : batch size up to 27,000 vials for 5ml vials.

Tailored 125I labeling

• Iodization and purification of your antigen (hapten, peptide, protein) either by gel filtration or HPLC.

Mabs fragmentation

• From the antibodies you send us we can produce F(ab’)2 fragments on a large scale.

Labeling Services

• Labeling of your antibody or antigen (hapten, peptide) with several markers such as peroxidase, biotin, fluorescent tag or other labels.

Antibody Purification

• Whatever antibody you send us we can purify it by protein-A, protein-G or caprilic acid precipitation and even by affinity chromatography.

Article 1 – ApplicationUnless there is an explicit deviation agreed upon in writing, the present general terms and conditions apply to every DIAsource offer as well as every contract that is formed on the basis of such an offer or an order confirmed by DIAsource. The client waives explicitly and fully the application of its own general terms and conditions by virtue of its relationship with DIAsource. Contracts that have been concluded through the staff or representatives of DIAsource and that do not observe these general terms and conditions do not bind DIAsource.

Article 2 – Conclusion of the contractAn offer from DIAsource is only binding if it is accompanied by a period of acceptance and only if this period has not yet expired. A client’s order can only be considered accepted by DIAsource after DIAsource’s express written confirmation of that acceptance. As any order has its own specific characteristics and, therefore, the products ordered by one client cannot be redirected to another client, the client cannot cancel an accepted order whether in full or in part. If the client would cancel an accepted order, it will still have to pay the full price of the relevant order. DIAsource reserves the right to (i) refuse requests for customized orders, or requests for modifications of accepted orders; and/or to (ii) charge such modifications or customizations to the client at the then-prevailing actual cost, with a minimum of 25 EUR (excl. VAT). Without prejudice to the third paragraph of this article 2, an administrative fee of 25 EUR (excl. VAT) will be charged by DIAsource for any order with a value of less than 500 EUR (excl. VAT).

Article 3 – Price and related costsUnless agreed otherwise in writing, all of DIAsource’s set prices apply to packaged products that are delivered Ex Works (in the sense of Incoterms 2010) to the registered seat of DIAsource. The following, on top of the stipulated price, are to be paid by the client, unless there is any explicit written deviation from this rule:

(i) All costs of insurance, security, loading, transport, and unpacking of the products.(ii) All taxes and levies (including VAT and customs duties) related to the delivered

products or the items mentioned under (i), including the taxes and levies that are applied or adapted only after the conclusion of the contract.

(iii) All additional costs for DIAsource that have been incurred as a result of differences in the currency exchange rates that are detrimental to DIAsource. Every cost that is charged for execution of payments must always be borne by the client ultimately.

Article 4 – PaymentUnless agreed on otherwise, (i) if DIAsource sends a pro forma invoice to the client, such pro forma invoice must be paid before the confirmed shipment date and (ii) if DIAsource does not send a pro forma invoice to the client, all invoices should be paid upon receipt. The payment of a (pro forma) invoice may not be refused or postponed for any reason whatsoever. Any late payment will make all debts of the client to DIAsource immediately due upon notification to that effect by DIAsource. An interest on late payment will be charged—ex officio and without notice—on the unpaid balance of all debts of the client to DIAsource which are due and payable, and the rate of it will be equal to the interest rate calculated according to Article 5, paragraph 2 of the Act of 2 August 2002 on combating late payments in commercial transactions, increased by 3.5% per year. On top of this, a compensation of 15% of the unpaid balance will be charged to cover the administrative costs associated with late payments, and this at a minimum of EUR 100 per invoice that is paid late. All of this is without prejudice to (i) the possibility for DIAsource to prove the actual damage it suffered and to demand compensation for it, or (ii) the possibility for DIAsource to suspend the further performance of its obligations under this or any other contract with the client, or apply any other common law sanction.

Article 5 – Reservation of ownership – transfer of riskThe ownership of every sold product only passes to the client after the client has fully paid the price and related costs for this product, as well as the late interest and compensation that would be due by virtue of late payment of this price. Before full payment is made, and unless explicitly agreed otherwise in writing, the client may not alienate the product, encumber it with securities, or transform it or attach it to an immovable property in any way; in that time span, the client will conserve the product safely and have it insured; it will also conserve it in a way it can be identified individually, with a legible and visible mark on it, explicitly confirming that it is property of DIAsource. The risk of loss, destruction, or damage to the product (also if caused by force majeure) will nevertheless pass to the client as soon as the product is delivered to the client.

Article 6 – Delivery PeriodEvery agreed upon delivery term is only (and is to be considered) indicative. Not observing this term does not entitle the client to any remedy, unless the parties agree explicitly in writing that the delivery term is binding (in that event, not observing the delivery term can only give way to indemnification for the damage

that is actual, proven, and established in such a way that both parties are able to submit observations, or to the termination of the sale, any of which can only be sought at the earliest 1 month from the date of a notice demanding delivery).

Article 7 – Hardship

If, beyond the will of DIAsource, unforeseen circumstances (e.g., strike, accidents, weather conditions, material defects, etc.) materialize in the procurement-, production-, distribution- or any other necessary type of process that make the delivery or timely delivery or the performance of any other obligation impossible (or strongly impede this), then DIAsource, depending on the nature of the circumstances, has the right to terminate the contract or suspend the performance of its obligations. DIAsource will not incur any liability if this occurs.

Article 8 – ComplaintsComplaints regarding visible defects or non-conformity are only admissible if (i) the product has not been used yet, and (ii) the complaint is in writing and is sent to the commercial services department of DIAsource in Louvain-La-Neuve no later than 3 working days from the date of delivery. After that, the products will irrefutably be considered accepted. Following complaints are also non-receivable: anonymous complaints, claims related to results dating more than a year before the introduction of the same complaint, complaints linked to a "mistake" of the customer "(ex: mishandling, error in following the protocol, etc.), claims related to facts that are not within the competence of DIAsource, claims relating to a failure to provide information by the client, claims related to a subjective nature of the said claim.

Article 9 – Liability/SecurityDIAsource will only be liable for hidden defects if the client notifies DIAsource thereof by registered letter within 7 business days after such hidden defects are discovered by the client. This term is to be considered a term unable to be suspended or reset (“délai de déchéance” / “vervaltermijn”). In that event, the client will not be entitled to claim the dissolution of the sale of the relevant product, and DIAsource will only be liable for (i) the decrease in value of the product, and, to the extent DIAsource can be held liable for it, and (ii) the additional damage suffered by the client, it being understood that the client bears the burden of proof. This indemnity (i & ii) will in any event be limited to the price paid by the client for the relevant product. The client must conform strictly with the directives regarding the good distribution practices (GDP) applicable to medical devices marked ‘CE’. The client must use the products in a professional way and in accordance with the instructions of DIAsource. The client must inform DIAsource immediately of any dysfunction or any alteration of the properties and/or performances of the product he has bought from DIAsource. If the products are resold by the client to a third party outside of Belgium, the client must provide all documents and necessary instructions to that third party in the language(s) of the country of destination. DIAsource must only accept returned goods to the extent that they are the subject of a complaint which DIAsource has declared admissible and well-founded.

Article 10 – Netting in case of insolvency of the clientIn case the client is declared bankrupt, or in case any other insolvency or insolvency-like procedure is initiated in respect of the client, any amounts reciprocally due by and between DIAsource and the client shall be netted automatically and by force of law on the date of the opening of the insolvency procedure, regardless of whether such amounts are already due or determined (“vaststaand”/“liquide”) on the date of the opening of the insolvency procedure, and even if they are not entirely certain.

Article 11 – No assignmentThe client may not assign its rights and obligations against DIAsource to any third party (through a sale, a capital contribution, a donation or any other transaction, including the sale or contribution of a division (“bedrijfstak”/“branche d’activité”) or of a business as a whole (“algemeenheid/ “universalité”), or a merger, spin-off, split-up or other corporate restructuring) without the prior written consent of DIAsource.

Article 12 – Applicable law and competent courtBelgian law applies to all agreements to which the present general terms and conditions apply, but with the exclusion of the application of Belgian private international law and the Convention on the International Sale of Goods of Vienna dated 11 April 1980 (except for the Convention on the Limitation Period in the International Sale of Goods of 14 June 1974, whose application remains). The courts of Walloon Brabant, Belgium are exclusively competent to hear all disputes arising out of or in connection with contracts concluded by DIAsource (including the pre-contractual disputes) to which the present general terms and conditions apply.

Article 13 – Discrepancies between language versionsThe present general terms and conditions have been drafted in Dutch, English, French and Spanish. In case of discrepancies between the different language versions, the French version will prevail.

GENERAL CONDITIONS OF SALES

15 14

AVAILABLE ASSAYS - SUMMARYProduct name Cat# Page

BirdCORTISOL-RIA-CT KIPI28000 11

BovineBHV-1 Ab ELISA BHd480 9

IBR-gB ELISA IBR192 9

BVD-MD Ab ELISA BVD480 9

EBLV Ab ELISA EBL480 9

Albumin ELISA RSHAKRBS018R 6

Insulin ELISA KAP1251 8

Insulin IRMA KIP1251 11

CanineBorrelia IgM/IgM ELISA DBGM96 9

Clusterin ELISA RD491034200R 6

hsCRP ELISA RH931CRP01DCR 6

Cystatin C ELISA RD491009100R 6

Ghrelin Acylated ELISA RA494062500R 6

Insulin ELISA RSHAKRIN012TR 6

Procalcitonin ELISA RD491488200R 6

Prolactin ELISA RTRTC022R 6

TSH ELISA RTC019R 6

Uromodulin ELISA RVRD491163200R 6

Insulin Elisa KAP1251 8

CORTISOL-RIA-CT KIPI28000 11

PROG-RIA-CT KIP1458 10


T4-RIA-CT KIP1641 10

E2-RIA-CT KIP0629 10

Testo-RIA-CT KIP1709 10

Food 16 Screen IgG ILE-SCH21 5

Food 16 Screen IgE ILE-SCH20 5

CatInsulin IRMA KIP1251 11

E2-RIA-CT KIP0629 11

Testo-RIA-CT KIP1709 11

Cortisol RIA CT KIPI28000 11

Food 16 Screen IgG ILE-SCK21 5

Food 16 Screen IgE ILE-SCK20 5

FishIPNV Ag ELISA IPN096 9

SVCV Ag ELISA SVC096 9

VHSV Ag ELISA VHS096 9

Gastropod1.25(OH)2 Vit D RIA KIP1929 10

HorseCORTISOL-RIA-CT KIPI28000 11


T3-RIA-CT KIP1631 11

Feed 8 Screen IgE ILE-SCP20 5

Feed 8 Screen IgG ILE-SCP24 5

Perennial 16 Screen IgE ILE-SCP21 5

Seasonal 16 Screen IgE ILE-SCP22 5

Insects 7 Screen IgE ILE-SCP23 5

MonkeysICAM-1 ELISA RAF103R 7

Interleukin-10 ELISA RAF029R 7

Interleukin-12 (p70) ELISA RAF032R 7




sPECAM-1 ELISA RAF110R 7

sP-Selectin ELISA RAF112R 7

TNF-alpha ELISA RAF099R 7

sTNF-R I ELISA RAF116R 7

sVE-Cadherin ELISA RAF120R 7

Cpep II ELISA KAP0401 8

IFNgamma ELISA KAP1231 8

IL-1Beta KAP1211 8

IL-6 ELISA KAP1261 8




TNFalpha ELISA KAP1751 8

Mouse1,25(OH)2 Vit D ELISA KAP1921 8

RIAZENco Aldosterone R-CW-100 12

PorcineAD Ab ELISA AD0480 9

Ghrelin Acylated ELISA RA594062400R 7

Ghrelin Unacylated ELISA RA594063400R 7

IFN-alpha 1 ELISA RA19016R 7

IFN-gamma 1 ELISA RA19017R 7

Insulin ELISA RSHAKRIN013TR 7

Interleukin-10 ELISA RA19020R 7

Interleukin-6 ELISA RA19019R 7

TNF-alpha ELISA RA19018R 7


Insulin ELISA KAP1251 8



RatRat 25OH Vitamin D Total ELISA KRR1971 8

ACTH IRMA KIP0061 10

Product name Cat# Page

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MANUFACTURED BY : DIAsource ImmunoAssays® S.A.rue du Bosquet 2 - BE 1348 Louvain-la-Neuve - BelgiumTel. : +32 (0)10 84 99 11 - Fax : +32 (0)10 84 99 90 [email protected] - [email protected]

FOR MORE INFORMATION : www.diasource-diagnostics.com

DISTRIBUTED BY :

LIT10

00

MS-

19

01

VITAMIN D

ANTIBODIES • Bone Metabolism

• Cancer Markers

• Cardiovascular & Salt Balance

• Diabetes & Metabolism

• Fertility

• Growth Factors

• Thyroid Function

IMMUNOASSAYS • Auto-Immunity

• Biogenic Amines

• Bone Metabolism

• Cancer Markers

• Cardiovascular & Salt

Balance

• Diabetes & Metabolism

• Fertility

• Gastrointestinal

Metabolism

• Growth Factors

• Immunology Markers

• Infectious Diseases

• Thyroid Function

INSTRUMENTS • Automated System for ELISA & RIA

• Automated Processor

for DOT Technology “Auto-Immunity”

• ELISA Instruments

ELISA , ANTIBODIES

& INSTRUMENTS

RIA

multi-species assays€¦ · 2 3 table of contents our company p. 3 to contact us p. 4 allergy p. 5...

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