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Mutations In DNA. By Mr. Guardiola. Interphase. Cell Growth Protein Synthesis: Transcription  Translation. Replication. Cell Division. Mitosis. Translation The ribosome and tRNA helps assemble the protein chain of amino acids. - PowerPoint PPT Presentation

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Page 1: Mutations In DNA

By Mr. Guardiola

Page 2: Mutations In DNA

TranslationThe ribosome and tRNA helps assemble the protein chain of amino acids. Replication

Replication

Cell GrowthCell GrowthProtein Synthesis:Protein Synthesis:

TranscriptionTranscription

TranslationTranslation

Cell

Cell

Divisio

n

Divisio

n

MET LEUTHRARG

The amino acids are bonded together to start the protein chain.

Page 3: Mutations In DNA
Page 4: Mutations In DNA
Page 5: Mutations In DNA
Page 6: Mutations In DNA

Mutations – Changes In DNACorrect Sequence:

MET TYRTHRARG

MET TYRTHRHIS

TAC GCA ATATGGAUG CGU UAUACC

Substitution

DNAmRNA

TAC GTA ATATGG

AUG CAU UAUACC

DNA

mRNA

THE FTT ATECAT

THE FAT ATECAT

Point Mutation

Page 7: Mutations In DNA

MET TYRTYRPRO

THE FFA TAT ETCA

Insertion of another “G”

TAC GGC GAT AATGAUG CCG CUA UUAC

DNAmRNA

MET PROVAL

THE ATC TEATA

Deletion of “G”

TAC CAT TAGGAAUG GUA AUCCU

DNAmRNA

Frameshift MutationsInsertion Deletion

Mutations – Changes In DNACorrect Sequence:

MET TYRTHRARG

TAC GCA ATATGGAUG CGU UAUACC

DNAmRNA

THE FAT ATECAT

Page 8: Mutations In DNA
Page 9: Mutations In DNA

 Chromosomal MutationThis involves the whole chromosome.Section 12-4

Page 10: Mutations In DNA

DNA (Gene) Mutations

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