mycology -dr. hashemi.ppt · mycology introduction. essential growth factors....
TRANSCRIPT
![Page 1: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/1.jpg)
١١
![Page 2: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/2.jpg)
mycologymycologymycologymycologyIntroductionIntroductionIntroduction.Introduction.Essential growth factors.Essential growth factors.Classification of fungiClassification of fungiClassification of fungi.Classification of fungi.Clinical syndromes.Clinical syndromes.Colonization and resultant disease.Colonization and resultant disease.Superficial Mycoses.Superficial Mycoses.Cutaneous Mycoses.Cutaneous Mycoses.Systemic MycosesSystemic Mycoses. .
٢٢
y yy y
![Page 3: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/3.jpg)
IntroductionIntroductionF i h t i d ithF i h t i d ithFungi are characterized withFungi are characterized with
Heterotrophic, Eukaryotic, non ChlorophyllHeterotrophic, Eukaryotic, non Chlorophyll ..Are not obligate animal parasites butAre not obligate animal parasites butAre not obligate animal parasites but Are not obligate animal parasites but Dermatophites.Dermatophites.Fewer than Fewer than 100 100 speciesspecies are associated with are associated with pphuman diseases.human diseases.
٣٣
![Page 4: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/4.jpg)
٤٤
![Page 5: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/5.jpg)
Essential growth factorsEssential growth factorsEssential growth factorsEssential growth factors
Carbon sourceCarbon source for energy metabolism andfor energy metabolism andCarbon sourceCarbon source for energy metabolism and for energy metabolism and structure. structure. NitNit f t b li ti df t b li ti dNitrogen sourceNitrogen source for metabolic reactions and for metabolic reactions and structure.structure.Purine and pyrimidinePurine and pyrimidine for synthesis of for synthesis of Nucleic acids and chitin. Nucleic acids and chitin.
٥٥
![Page 6: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/6.jpg)
Circumstances for growthCircumstances for growthOptimum Optimum thermal growth in thermal growth in 2222--2727 ْ◌ ْ◌ C. C. ..Optimum Optimum PH for growth in PH for growth in 55..66--77. . ..Optimum Optimum Humidity for growth in Humidity for growth in 7575--8585%.%.
٦٦
![Page 7: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/7.jpg)
٧٧
![Page 8: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/8.jpg)
ClassificationClassificationClassification Classification
PhylumPhylum ChitiridiomycotaChitiridiomycota ((O t )O t )Phylum,Phylum,Chitiridiomycota.Chitiridiomycota.((Oomycete)Oomycete)
Phylum, Phylum, Dikariomycota:Dikariomycota:Sub phylum,Sub phylum, ZygomycotaZygomycota..(Rhyzopus,mucor)(Rhyzopus,mucor)
Sub phylum, Sub phylum, Ascomycta.Ascomycta.((Dermatophytes, Histoplasma)Dermatophytes, Histoplasma)p y ,p y , yy (( p y p )p y p )
SubPhylumSubPhylum,Basidiomycota,Basidiomycota..((Cryptococcus)Cryptococcus)
SubphylumSubphylum DeutromycotaDeutromycota (C did M l i )(C did M l i )Subphylum,Subphylum,DeutromycotaDeutromycota..(Candida, Malassezia)(Candida, Malassezia)
٨٨
![Page 9: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/9.jpg)
Clinical SyndromesClinical SyndromesClinical SyndromesClinical Syndromes
Mycotoxicosis & Mycetismus. Mycotoxicosis & Mycetismus. ..Hypersensitivity Diseases. Hypersensitivity Diseases. ..Colonization of the host and infectionColonization of the host and infection. .
٩٩
![Page 10: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/10.jpg)
١٠١٠
![Page 11: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/11.jpg)
Colonization and InfectionColonization and InfectionColonization and InfectionColonization and Infection
Superficial MycosesSuperficial MycosesSuperficial MycosesSuperficial MycosesCutaneus MycosesCutaneus MycosesSubcutaneus MycosesSubcutaneus MycosesSystemic MycosisSystemic Mycosisy yy yOpportunistic MycosesOpportunistic Mycoses
١١١١
![Page 12: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/12.jpg)
Diagnostic methodsDiagnostic methodsDiagnostic methodsDiagnostic methods
Wood’s lightWood’s light::Wood s lightWood s light: : ((fluorescent lesions under UV in λ=fluorescent lesions under UV in λ=395 395 n.m)n.m)Direct examination:Direct examination:Direct examination: Direct examination: KOH method,KOH method, squeezed preparation, scotch squeezed preparation, scotch tape method, stained preparationtape method, stained preparation..tape method, stained preparationtape method, stained preparation..Culture: On variable media, Culture: On variable media, teased mount,teased mount,slide culture method.slide culture method.slide culture method.slide culture method.Serology: Serology: ID, CIE,ID, CIE, CF, LATCF, LATMolecular:Molecular: PCRPCR
١٢١٢
Molecular: Molecular: PCRPCR
![Page 13: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/13.jpg)
Basic culture mediaBasic culture mediaBasic culture media Basic culture media
S: sabouraud dextrose agarS: sabouraud dextrose agarS: sabouraud dextrose agarS: sabouraud dextrose agarSC: S+ChloramphenicoleSC: S+ChloramphenicoleSCC: SC+cyclohexamideSCC: SC+cyclohexamideCMA: Corn Meal AgarCMA: Corn Meal AgarggPDA: Potato Dextrose AgarPDA: Potato Dextrose AgarPFA: Potato Flake AgarPFA: Potato Flake AgarPFA: Potato Flake AgarPFA: Potato Flake AgarCzapek Dox AgarCzapek Dox Agar
١٣١٣
![Page 14: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/14.jpg)
Superficial MycosesSuperficial MycosesSuperficial MycosesSuperficial Mycoses
Pityriasis versicolorPityriasis versicolorPityriasis versicolorPityriasis versicolorPityrosporosisPityrosporosisTinea nigraTinea nigraErythrasmaErythrasmayyPiedraPiedraOtomycosisOtomycosisOtomycosisOtomycosis
١٤١٤
![Page 15: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/15.jpg)
١٥١٥
![Page 16: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/16.jpg)
Pit i iPit i iPityriasis Pityriasis yyversicolorversicolorversicolorversicolor
١٦١٦
![Page 17: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/17.jpg)
DefinitionDefinitionDefinitionDefinition
AA chronic recurrentchronic recurrent macularmacular superficialsuperficialA A chronic, recurrentchronic, recurrent,, macularmacular, superficial , superficial fungal infection. fungal infection. ..Caused by: Caused by: Malassezia fur furMalassezia fur fur ,M globosa,M ,M globosa,M
t i t M di li M l f Mt i t M di li M l f Mrestricta,M sympodialis,M sloofeae,M restricta,M sympodialis,M sloofeae,M pachydermatis,M obtusa M dermatis,M pachydermatis,M obtusa M dermatis,M
M iM inana,M equinana,M equi the lipophilic yeast , encountered in skin .the lipophilic yeast , encountered in skin .
١٧١٧
![Page 18: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/18.jpg)
Clinical manifestationClinical manifestationClinical manifestationClinical manifestation
MacularMacular sharply marginated very slightly raisedsharply marginated very slightly raisedMacular,Macular, sharply marginated, very slightly raised.sharply marginated, very slightly raised.Sites of infection : Sites of infection : Neck, flexor, aspects of arms, Neck, flexor, aspects of arms, abdomen axillae and pubic areaabdomen axillae and pubic areaabdomen, axillae and pubic area.abdomen, axillae and pubic area.Papular form on seborrheic area of trunkPapular form on seborrheic area of trunk..World wideWorld wideWorld wide.World wide.common in hot and humid climates.common in hot and humid climates.Treatment:Treatment: White field selenium sulfideWhite field selenium sulfideTreatment: Treatment: White field, selenium sulfide White field, selenium sulfide Clotrimazol, MiconazolClotrimazol, Miconazol
١٨١٨
![Page 19: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/19.jpg)
١٩١٩
![Page 20: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/20.jpg)
٢٠٢٠
![Page 21: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/21.jpg)
٢١٢١
![Page 22: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/22.jpg)
٢٢٢٢
![Page 23: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/23.jpg)
٢٣٢٣
![Page 24: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/24.jpg)
٢٤٢٤
![Page 25: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/25.jpg)
٢٥٢٥
![Page 26: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/26.jpg)
٢٦٢٦
![Page 27: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/27.jpg)
٢٧٢٧
![Page 28: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/28.jpg)
٢٨٢٨
![Page 29: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/29.jpg)
٢٩٢٩
![Page 30: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/30.jpg)
٣٠٣٠
![Page 31: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/31.jpg)
٣١٣١
![Page 32: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/32.jpg)
٣٢٣٢
![Page 33: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/33.jpg)
Mycological DiagnosisMycological DiagnosisMycological DiagnosisMycological Diagnosis
Macroscopically observationMacroscopically observation goldishgoldish--yellowyellowMacroscopically observation Macroscopically observation goldishgoldish--yellow yellow fluorescence in front of Woods light.fluorescence in front of Woods light.Direct smear:KOHDirect smear:KOH 1010--2020% or scotch tape% or scotch tapeDirect smear:KOH Direct smear:KOH 1010--2020% or scotch tape.% or scotch tape.Microscopically result:Microscopically result:Spaghetti and Spaghetti and meatball or blastoconidia andmeatball or blastoconidia andmeatball or blastoconidia and meatball or blastoconidia and pseudohypha.pseudohypha.Culture:Culture: Is not necessaryIs not necessary in ordinary clinicalin ordinary clinicalCulture: Culture: Is not necessaryIs not necessary in ordinary clinical in ordinary clinical situation .situation .S+streptomycin+sterile olive oilS+streptomycin+sterile olive oil
٣٣٣٣
S+streptomycin+sterile olive oil. S+streptomycin+sterile olive oil.
![Page 34: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/34.jpg)
٣٤٣٤
![Page 35: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/35.jpg)
٣٥٣٥
![Page 36: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/36.jpg)
٣٦٣٦
![Page 37: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/37.jpg)
٣٧٣٧
![Page 38: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/38.jpg)
٣٨٣٨
![Page 39: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/39.jpg)
٣٩٣٩
![Page 40: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/40.jpg)
٤٠٤٠
![Page 41: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/41.jpg)
٤١٤١
![Page 42: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/42.jpg)
٤٢٤٢
![Page 43: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/43.jpg)
٤٣٤٣
![Page 44: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/44.jpg)
TreatmentTreatmentTreatmentTreatment
SulfurSulfur 33%%Sulfur Sulfur 33%%Salicylic acid Salicylic acid 22%%ClotrimazoleClotrimazoleKetoconazoleKetoconazole
٤٤٤٤
![Page 45: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/45.jpg)
٤٥٤٥
![Page 46: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/46.jpg)
DandruffDandruffDandruffDandruff
٤٦٤٦
![Page 47: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/47.jpg)
PityrosporosisPityrosporosisPityrosporosisPityrosporosis
Definition: Seborrheic dermatitidis orDefinition: Seborrheic dermatitidis orDefinition: Seborrheic dermatitidis or Definition: Seborrheic dermatitidis or Pityriasis simplex, A chronic superficial Pityriasis simplex, A chronic superficial infection with scalesinfection with scales (dandruff).(dandruff).infection with scales infection with scales (dandruff).(dandruff).Cause: Cause: Malassezia globosa, Malassezia Malassezia globosa, Malassezia resticta .resticta .resticta .resticta .Clinical manifestation: Clinical manifestation: Seborrhea sicca, Seborrhea sicca, Oleasa and EczemaOleasa and Eczema, scales appears on, scales appears onOleasa and EczemaOleasa and Eczema, scales appears on , scales appears on scalp and face. scalp and face. Treatment: Selenium sulfide, Perithion zincTreatment: Selenium sulfide, Perithion zinc
٤٧٤٧
eat e t Se e u su de, e t o ceat e t Se e u su de, e t o c
![Page 48: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/48.jpg)
٤٨٤٨
![Page 49: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/49.jpg)
٤٩٤٩
![Page 50: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/50.jpg)
٥٠٥٠
![Page 51: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/51.jpg)
٥١٥١
![Page 52: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/52.jpg)
٥٢٥٢
![Page 53: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/53.jpg)
Mycological DiagnosisMycological DiagnosisMycological DiagnosisMycological Diagnosis
Direct examination: Skin scrapping fromDirect examination: Skin scrapping fromDirect examination: Skin scrapping from Direct examination: Skin scrapping from seborrheric lesions. seborrheric lesions. Squeezing in a drop of Squeezing in a drop of water staining with methylene blue showwater staining with methylene blue showwater staining with methylene blue show water staining with methylene blue show large numbers of budding cells.large numbers of budding cells.C ltC lt i ti t t k tht k thCulture: Culture: is not necessaryis not necessary to make the to make the diagnosis.diagnosis.
٥٣٥٣
![Page 54: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/54.jpg)
٥٤٥٤
![Page 55: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/55.jpg)
٥٥٥٥
![Page 56: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/56.jpg)
٥٦٥٦
![Page 57: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/57.jpg)
٥٧٥٧
![Page 58: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/58.jpg)
٥٨٥٨
![Page 59: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/59.jpg)
٥٩٥٩
![Page 60: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/60.jpg)
MalasseziaMalassezia yeastsyeasts
Basidiomycetous yeastsBasidiomycetous yeastsBasidiomycetous yeastsBasidiomycetous yeastsMonopolar budidingMonopolar budidingLipid Lipid –– dependent or lipophilicdependent or lipophilicCurrently Currently 10 10 species (+ species (+ 2 2 ))yy p ( _p ( _ ))
٦٠٦٠
![Page 61: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/61.jpg)
TheThe speciesspeciesTheThe speciesspecies
M.furfurM.furfurM.globosaM.globosaM sympodialisM sympodialisM.sympodialisM.sympodialisM.pachydermatisM.pachydermatisM.obtusa M.obtusa M.restrictaM.restrictaM.slooffiae M.slooffiae M.dermatisM.dermatisM.nanaM.nanaM.equiM.equi
٦١٦١
![Page 62: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/62.jpg)
Skin diseasesSkin diseasesSkin diseasesSkin diseases
Pityriasis versicolorPityriasis versicolor: : M.globosa,M.globosa, M. sympodialis , M. sympodialis , M.slooffiae, M. restricta, M.furfur (rare) M.slooffiae, M. restricta, M.furfur (rare) Seborrheic dermatitisSeborrheic dermatitis:: M restrictaM restricta M globosaM globosaSeborrheic dermatitisSeborrheic dermatitis: : M.restricta,M.restricta, M. globosa, M. globosa, M.sympodialis, M. furfur (rare) M.sympodialis, M. furfur (rare) Atopic dermatitisAtopic dermatitis: : M.furfur,M.furfur, M. globosa andM. Restricta M. globosa andM. Restricta ((9090%%) , M. furfur and sympodialis, M.dermatis) , M. furfur and sympodialis, M.dermatis((9090%%) , M. furfur and sympodialis, M.dermatis) , M. furfur and sympodialis, M.dermatisMallassezia folliculitisMallassezia folliculitis: ?: ?DandrufDandruf::M. restricta and M.globosaM. restricta and M.globosaPsoriasisPsoriasis:: M globosaM globosa M slooffiae M restrictaM slooffiae M restrictaPsoriasisPsoriasis:: M. globosa,M. globosa, M. slooffiae, M. restricta M. slooffiae, M. restricta OnychomycosisOnychomycosis : : M.M. furfurfurfurMucosal sitesMucosal sites :: M. FurfurM. Furfur
٦٢٦٢
![Page 63: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/63.jpg)
Other clinical importance of Other clinical importance of Malassizia yeastMalassizia yeastMalassizia yeastMalassizia yeast
M furfurM furfur : systemic and mucosal sites: systemic and mucosal sitesM. furfurM. furfur : systemic and mucosal sites, : systemic and mucosal sites, bone marrow transplant patients bone marrow transplant patients (rare)neonate nosocomial out breaks(rare)neonate nosocomial out breaks(rare)neonate, nosocomial out breaks(rare)neonate, nosocomial out breaksM. PachydermatisM. Pachydermatis : neonates , nosocomial : neonates , nosocomial
tb ktb koutbreaksoutbreaks
٦٣٦٣
![Page 64: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/64.jpg)
AssociationsAssociations of Malasseziaof Malassezia ononskinskin
M. globosa , M. sympodialis, M sloofiaeM. globosa , M. sympodialis, M sloofiaePVPV و ھمچنين پوست سالمو ھمچنين پوست سالم اغلب دراغلب در
M.globosa +M.globosa + M. sympodialis M. sympodialis 3030% % PVPVgg y py pM. globosa + M. sloofiae M. globosa + M. sloofiae 77% % PVPV
٦٤٦٤
![Page 65: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/65.jpg)
Animal relationshipsAnimal relationshipsAnimal relationshipsAnimal relationships
CatCat: : M. pachydermatis , M. sympodialsis M. fur fur M. pachydermatis , M. sympodialsis M. fur fur DogDog:: M. pachydermatis, M. nana M. fur fur M. M. pachydermatis, M. nana M. fur fur M.
btbtobtuseobtuseHorseHorse:: M. fur fur. M sloofiae , Mobtusa, M. M. fur fur. M sloofiae , Mobtusa, M. globosa M. restricta . M. equiglobosa M. restricta . M. equiglobosa M. restricta . M. equi globosa M. restricta . M. equi CattleCattle:: M. globosa , M. furfur. M. sloofiae, M. M. globosa , M. furfur. M. sloofiae, M. sympoolialis, M. nana sympoolialis, M. nana ShSh M di li M l b M t i tM di li M l b M t i tSheepSheep:: M. sympodialis , M globosa , M. restricta M. sympodialis , M globosa , M. restricta OstrichOstrich:: M. furfur M. furfur
٦٥٦٥
![Page 66: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/66.jpg)
Significance of the currentlySignificance of the currentlyg yg yrecognized speciesrecognized species
Sampling is difficultSampling is difficultSampling is difficultSampling is difficultPurifying a culture is difficultPurifying a culture is difficult
٦٦٦٦
![Page 67: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/67.jpg)
Healthy skinHealthy skinHealthy skinHealthy skin
M. sympodialisM. sympodialis : Trunk (: Trunk (6060%) , glans penis%) , glans penisM. glogosaM. glogosa : scalp , forehead, trunk (: scalp , forehead, trunk (1010%) %)
l il iglopesis glopesis M.slooffiaeM.slooffiae : trunk (: trunk (11%) %) M restricaM restrica : scalp(: scalp(2020%)%)M. restricaM. restrica : scalp(: scalp(2020%) %) M. furfurM. furfur :low :low –– very low (but very low (but 1111% Japan)% Japan)M. pachydermatisM. pachydermatis : glans penis (: glans penis (44..11%)%)p yp y g p (g p ( ))NeonatiesNeonaties:: colonization with M. Sympodialis and colonization with M. Sympodialis and globosaglobosa
٦٧٦٧
![Page 68: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/68.jpg)
٦٨٦٨
![Page 69: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/69.jpg)
TreatmentTreatmentTreatmentTreatment
Selenium sulfideSelenium sulfideSelenium sulfideSelenium sulfideKetoconazoleKetoconazole
٦٩٦٩
![Page 70: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/70.jpg)
٧٠٧٠
![Page 71: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/71.jpg)
Tinea nigraTinea nigraTinea nigraTinea nigra
Definition:Definition:Definition: Definition: Disease of warm humid climates Disease of warm humid climates characterized bycharacterized by macules on glabrous skinmacules on glabrous skincharacterized by,characterized by,macules on glabrous skinmacules on glabrous skin..Cause: Cause: E hil kiiE hil kii (Cl d i kii(Cl d i kiiExophila werneckiiExophila werneckii (Cladosporium werneckii (Cladosporium werneckii A yeastA yeast--like dematiaceus fungus, like dematiaceus fungus, S b li i il t tiS b li i il t tiSaprobe, living soil or vegetations. Saprobe, living soil or vegetations.
٧١٧١
![Page 72: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/72.jpg)
Clinical manifestationClinical manifestationClinical manifestationClinical manifestation
Brownish or black maculesBrownish or black maculesBrownish or black maculesBrownish or black maculesOn glabrous skin: On glabrous skin: palm, sole, bodypalm, sole, bodySharply marginated, AsymptomaticSharply marginated, AsymptomaticLittle or Little or no scalesno scales on lesionson lesionsResemble to cutaneus Resemble to cutaneus silver nitrate stainssilver nitrate stains. .
٧٢٧٢
![Page 73: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/73.jpg)
٧٣٧٣
![Page 74: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/74.jpg)
MycologyMycologyMycologyMycology
Direct examination of skin scrapping byDirect examination of skin scrapping byDirect examination of skin scrapping by Direct examination of skin scrapping by KOH KOH 1010--20 20 %.%.R lt D kR lt D k t t h h d b ddit t h h d b ddiResult: Dark,Result: Dark, septate hyphae and budding septate hyphae and budding cells, swelling spores.cells, swelling spores.Culture: On sabouraud medium: Culture: On sabouraud medium: Yeast like cells often doublet form Yeast like cells often doublet form Dark,septate hyphae, clusters of conidiaDark,septate hyphae, clusters of conidia..Treatment: Treatment: salicilate salicilate 22%,%, sulfure sulfure 33%.%.
٧٤٧٤
,,
![Page 75: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/75.jpg)
٧٥٧٥
![Page 76: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/76.jpg)
٧٦٧٦
![Page 77: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/77.jpg)
ErythrasmaErythrasmaErythrasmaErythrasma
٧٧٧٧
![Page 78: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/78.jpg)
ErythrasmaErythrasmaErythrasmaErythrasma
Definition:Definition: MacularMacular lesions onlesions on wrinkle areawrinkle areaDefinition: Definition: MacularMacular, lesions on , lesions on wrinkle areawrinkle areaskin.skin.CC C b t i i ti iC b t i i ti i ffCause: Cause: Corynebacterium minutissimumCorynebacterium minutissimum from from diphtheroid bacteria.diphtheroid bacteria.Clinical manifestation: Red to Brownish red Clinical manifestation: Red to Brownish red and black macules on wrinkle area skin : and black macules on wrinkle area skin : groin, axilla and breast. groin, axilla and breast.
٧٨٧٨
![Page 79: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/79.jpg)
٧٩٧٩
![Page 80: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/80.jpg)
٨٠٨٠
![Page 81: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/81.jpg)
٨١٨١
![Page 82: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/82.jpg)
٨٢٨٢
![Page 83: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/83.jpg)
٨٣٨٣
![Page 84: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/84.jpg)
Mycological DiagnosisMycological DiagnosisMycological DiagnosisMycological Diagnosis
Direct Examination: Scrapping of macularDirect Examination: Scrapping of macularDirect Examination: Scrapping of macular Direct Examination: Scrapping of macular lesions lesions squeezing in a drop of watersqueezing in a drop of water. . Staining with gramStaining with gram oror methylene bluemethylene blue show:show:Staining with gramStaining with gram or or methylene bluemethylene blue show: show: Diphtheroid, China characters and Diphtheroid, China characters and filamentous bacilli gram positivefilamentous bacilli gram positivefilamentous bacilli, gram positivefilamentous bacilli, gram positive..Culture is not necessary. Culture is not necessary.
٨٤٨٤
![Page 85: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/85.jpg)
٨٥٨٥
![Page 86: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/86.jpg)
٨٦٨٦
![Page 87: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/87.jpg)
٨٧٨٧
![Page 88: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/88.jpg)
٨٨٨٨
![Page 89: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/89.jpg)
٨٩٨٩
![Page 90: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/90.jpg)
٩٠٩٠
![Page 91: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/91.jpg)
٩١٩١
![Page 92: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/92.jpg)
٩٢٩٢
![Page 93: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/93.jpg)
TreatmentTreatmentTreatmentTreatmentErythromycineErythromycine
٩٣٩٣
![Page 94: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/94.jpg)
٩٤٩٤
![Page 95: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/95.jpg)
Black piedraBlack piedraBlack piedraBlack piedra
Definition:Definition:Definition: Definition: A hair disease of western hemisphere A hair disease of western hemisphere tropicstropics and Indonesiaand Indonesiatropicstropics and Indonesia.and Indonesia.Cause: Cause: Pi d i h tPi d i h t b i h biti thb i h biti thPiedraia horteaPiedraia hortea; a saprobe inhabiting the ; a saprobe inhabiting the soil in tropics. soil in tropics.
٩٥٩٥
![Page 96: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/96.jpg)
Clinical manifestationClinical manifestationClinical manifestation Clinical manifestation
Black nodulesBlack nodules along the hair shaftalong the hair shaftBlack nodulesBlack nodules along the hair shaftalong the hair shaftMultiple, hard,Multiple, hard, firmly adherentfirmly adherentSize; up to Size; up to 11mm in diametermm in diameterOn hairs of the On hairs of the scalp, beard, moustachescalp, beard, moustache. . p, ,p, ,
٩٦٩٦
![Page 97: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/97.jpg)
٩٧٩٧
![Page 98: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/98.jpg)
MycologyMycologyMycologyMycology
Direct examination:Direct examination:Direct examination: Direct examination: Mature nodules containing Mature nodules containing asciasciPigmented hypheaPigmented hypheaPigmented hypheaPigmented hyphea..On sabouraud Agar after On sabouraud Agar after 21 21 days: days: D k thi k ll d d t t h hD k thi k ll d d t t h hDark, thick walled and septate hyphaeDark, thick walled and septate hyphaeSwollen cells and chlamydosporeSwollen cells and chlamydosporeS ti d ti fS ti d ti f iiSometimes production of Sometimes production of asciasci
٩٨٩٨
![Page 99: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/99.jpg)
White PiedraWhite PiedraWhite PiedraWhite Piedra
A hair disease seen occasionally inA hair disease seen occasionally in southsouthA hair disease seen occasionally in A hair disease seen occasionally in south south America.America...Cause: Cause: Trichosporon beigelliTrichosporon beigelli
٩٩٩٩
![Page 100: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/100.jpg)
Clinical ManifestationClinical ManifestationClinical ManifestationClinical Manifestation
Whitish or brownish nodulesWhitish or brownish nodules along hairshaftalong hairshaftWhitish or brownish nodulesWhitish or brownish nodules along hairshaft.along hairshaft.Size: up to Size: up to 11mm in diametermm in diameterHair are weak and fracturedHair are weak and fracturedThe favored sites; The favored sites; axilla, pubic hair, beard, axilla, pubic hair, beard, ;; , p , ,, p , ,moustache and scalp.moustache and scalp.
١٠٠١٠٠
![Page 101: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/101.jpg)
١٠١١٠١
![Page 102: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/102.jpg)
MycologyMycologyMycology Mycology
Direct examination:Direct examination:Direct examination: Direct examination: Blastoconidia and arthrosporesBlastoconidia and arthrospores within the within the hair shaft and on the surfacehair shaft and on the surfacehair shaft and on the surface.hair shaft and on the surface.Culture on Culture on Sabouraud medium, C.M.ASabouraud medium, C.M.A : : H h d d h hH h d d h hHyphae and pseudohyphae Hyphae and pseudohyphae Blastoconidia (single or short chains) Blastoconidia (single or short chains) A th ( t l )A th ( t l )Arthrospores (rectangular). Arthrospores (rectangular).
١٠٢١٠٢
![Page 103: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/103.jpg)
TreatmentTreatmentTreatmentTreatmentHgClHgCl22
١٠٣١٠٣
![Page 104: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/104.jpg)
١٠٤١٠٤
![Page 105: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/105.jpg)
M Fur furM Fur furM.Fur furM.Fur fur
١٠٥١٠٥
![Page 106: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/106.jpg)
M globosaM globosaM.globosaM.globosa
١٠٦١٠٦
![Page 107: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/107.jpg)
M pachydermatisM pachydermatisM.pachydermatisM.pachydermatis
١٠٧١٠٧
![Page 108: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/108.jpg)
M sympodialisM sympodialisM.sympodialisM.sympodialis
١٠٨١٠٨
![Page 109: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/109.jpg)
M slooffiaeM slooffiaeM.slooffiaeM.slooffiae
١٠٩١٠٩
![Page 110: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/110.jpg)
M obtusaM obtusaM.obtusaM.obtusa
١١٠١١٠
![Page 111: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/111.jpg)
M restrictaM restrictaM.restrictaM.restricta
١١١١١١
![Page 112: Mycology -Dr. Hashemi.ppt · mycology Introduction. Essential growth factors. ClassificationoffungiClassification of fungi. Clinical syndromes. Colonization and resultant disease](https://reader034.vdocuments.net/reader034/viewer/2022042512/5fa02fb8b7b4ea31b233e592/html5/thumbnails/112.jpg)
M dermatisM dermatisM.dermatisM.dermatis
١١٢١١٢