National Center for Emerging and Zoonotic Infectious Diseases

Office of the Director

Emerging and Zoonotic Infectious Diseases

May 14, 2015

Beth P. Bell, MD, MPHDirector

National Center for Emerging and Zoonotic Infectious DiseasesCenters for Disease Control and Prevention

• Foodborne illnesses• Infections that spread in

hospitals and other healthcare settings

• Infections that are resistant to antibiotics

• Deadly diseases like anthrax and Ebola

• Diseases caused by having contact with animals

• Diseases spread by mosquitoes, ticks, and fleas

• Illnesses that affect immigrants, migrants, refugees, and travelers

NCEZID: Protecting People from Infectious Disease

Signature Programs

EID Journal

National Healthcare Safety Network

The Yellow Book

Laboratory ResponseNetwork

PulseNet

Epidemiology and Laboratory Capacity for Infectious Diseases

Responding to Outbreaks Around the Globe

NCEZID has supported the response in several ways

• >300 NCEZID personnel deployed to West Africa• Hundreds of staff working in EOC• Others worked with US Customs & Border

protection to conduct screening at 5 US airports• Preparing US healthcare facilities to safely

manage a person with Ebola

Responding to Outbreaks in the USOutbreak of E. coli O157 infections in Washington

State, 2015

In 2014, NCEZID received 37 requests from states and other countries to assist in the investigation of outbreaks

• 15 lab-confirmed cases (no deaths) among ~1,000 children who attended Milk Makers Festival in Whatcom County April 21-23

• CDC sent Epi Aid team to investigate• Objectives: identify risk factors, prevent additional

transmission, prevent similar outbreaks in the future

Collaborating with States: Botulism outbreak in Ohio, 2015

• April 19 church potluck meal attended by ~77 people• 22 confirmed cases, including 1 death and 9 suspected

cases• Likely source of outbreak: potato salad from home-canned

potatoes• CDC provided antitoxin; worked closely with Fairfield

County Health Department and Ohio Department of Health, which provided outstanding leadership in triage of patients and managing response

Strengthening State and Local Capacity

Epidemiology and Laboratory Capacity for Infectious Diseases Cooperative Agreement (ELC)

$97.2M awarded in 2014• Supports 50 state health departments, 6

largest local health departments, and 8 territories or US affiliates

• Works with CDC partner infectious disease programs to support >20 specific disease areas, e.g., influenza, foodborne disease, HAI• Through PPHF, ELC also provides cross-cutting and flexible support for infectious disease epidemiology, laboratory and health information systems

Emerging Infections Program (EIP)

• 10 state health departments and university partners

• Gold standard surveillance translated into policy and public health practiceDisease burden estimates, tracking trends, evaluation of the

impact of vaccination programs and other public health interventions, capacity to rapidly implement special projects.

Preventing and Controlling Vector-borne Diseases

Significant cause of severe illness and death High cost due to health care, lost income and

vector control Vector-borne diseases are on the rise – increasing

in incidence, distribution, and severity No vaccines to prevent or drugs to treat most viral

vector-borne threats Domestic outbreak threats are driven by

globalization, changing ecology, and emerging pathogens: Lyme disease West Nile disease Chikungunya Japanese encephalitis Dengue

3

Preparing for Chikungunya

• New mosquito-borne disease in Western Hemisphere • CDC has prepared for outbreaks since 2009

– Improve diagnostic capacity

– Assess gaps in state/local capabilities to detect and respond to outbreaks

– Develop and disseminate guidelines, information and education materials for all audiences

– Aid state/local health department investigations

Protecting Against Importation of Infectious Diseases

• Quarantine Stations at 20 U.S. Ports of Entryo Detect and respond to communicable diseases related to

travel and imported pathogens• Travelers’ Health

o Safeguard the health of U.S. residents traveling abroad• Immigrant, refugee, and migrant health

o Provide guidelines for screening/treating refugees and immigrants to U.S.; track diseases in these populations

Championing Innovation: Advanced Molecular Detection

AMD combines• Traditional epidemiology• Genomic sequencing• Bioinformatics

AMD in Action • Listeria in Blue Bell products• Bourbon virus discovery• Listeria in caramel apples

• Emerging organisms

• Drug resistance• Intentional

creation

• Societal commitment

• New technologies

• Success leads to success

• Prevent wherever possible

• Detect rapidly• Respond

effectively

3 3 3 Risks Opportunitie

s Priorities

Supporting Global Health Security

© David Snyder/CDC Foundation

For more information please contact Centers for Disease Control and Prevention1600 Clifton Road NE, Atlanta, GA 30333Telephone, 1-800-CDC-INFO (232-4636)/TTY: 1-888-232-6348E-mail: cdcinfo@cdc.gov Web: www.cdc.gov

The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention.

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Centers for Disease Control and Prevention

National Center for Emerging and Zoonotic Infectious Diseases