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Ministry of Health & Population (MOHP)

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National Essential Drug List &Guidelines

2006

EGYPT Technical Research and Training Department (TRTD) Central Administration of Pharmaceutical Affairs (CAPA)

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:Foreword�

The first Essential Drug List and Guidelines was issued in the year 1998. The Essential Drug concept was adopted in developing the Essential Drug List and Guidelines as one of the ways and means to ensure that the pharmaceutical products included in the list are available when and where they are needed.

Furthermore, the list helps to reduce the number of drugs and to lower the cost. Essential Drugs are crucial to the success of health programs; the drugs are part of the final link between health services. For all the above reasons, it was very important to update the Essential Drug List to comply with the strategy of the Ministry of Health and Population (MOHP) . "Health for all " is the ultimate goal of all endeavors of MOHP. For the sake of patients we do our best to ensure safety, efficacy, quality, and affordability of drugs. I would like to express my deep thanks and appreciation to all experts who participated in updating the list, revising the text, and made the final editing.

My sincere thanks are also extended to the experts who prepared the first edition.

Minister Of Health & Population

Prof. Dr. Hatem El Gabaly

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For the optimal use of the limited financial resources for health in developing countries the availability of drugs must be restricted to those proven to be therapeutically effective, to have acceptable safety and to satisfy the health needs of the population. These selected drugs are labeled "Essential" indicating they are the basic and necessary group of agents that are needed to meet the health needs of the population. The primary concept behind the use of the list of essential drugs is to reduce the number of drugs available. This will assist in the monitoring of the quality and availability of drugs in order to avoid waste and to concentrate on the pharmaceutical agents within Egypt.

The advantages of an essential drug list are: 1. Reduced number of pharmaceutical products. 2. Reduced cost. 3. Improved procurement, storage and distribution and local availability. 4. Fewer drugs for quality control. 5. Training is easier with fewer drugs. 6. Improvement in the quality of drug utilization, management, information and monitoring. 7. Providing a stimulus to the local pharmaceutical industries to supply essential,

generically labeled drugs, which will reduce expenditures and minimize drug importation.

The aim of the "Essential Drug Committee" is to establish an up-to-date, essential drug list for different levels of health care in Egypt. Every drug is identified using a coding system that assigns that drug to a specific health care level. For each generic name, the health care level is placed on the right side of the page framed within a black box.

The levels are:

1: for use by all medical professionals. 2: for use only by medical specialist and consultant physicians. 3: for use only by consultant physicians. The drugs selected for this list are described both using generic and brand names to facilitate the selection of the most appropriate drug product. In selection these factors were considered:

• Source of raw material. • Innovator or generic. • Organoleptic properties. • Stability (Accelerated, real time, climatic zone). • Bioavilability and bioequivalence.

INTRODUCTION

• Drug history (benefit/risk ratio). • Cost. This multi-level essential drug list has these characteristics :

• Consistent with the pattern of prevalent diseases. • Simple drugs are always selected. Combinations of drugs are limited. • Contains a common core with universal relevance and application. • Indicates priorities in drug needs. • Contains drugs, which are available at all times in adequate amounts and in the proper dosage forms at a suitable price.

• Flexible enough to meet the changing priorities in health care. The chosen drugs are Written in generic and taken into consideration in selecting a brand are illustrated.

•The different levels were assigned on the bases of the requirements of working physicians in various care settings. The Arrangement of the updated Essential Drug List:

Part 1 (page 1-18) contains the National Essential Drug List (EDL) under its Nonproprietary names (Generics). Part 2 (page 1 - 137) contains monographs on non-proprietary drugs of the list arranged under therapeutic categories. Each monograph includes basic information such as indications, side effects, contraindications, interactions, precautions and doses. Part 3 (page 1 - 31) contains proprietary names of generics that are included in the essen-tial drug list. For the proprietary preparations, the information provided includes the trade name, the manufacturer, units in one pack, dosage form, and the retail price. Index : A general index to make fullest use of the contents of this book.

Members of High Expert Committee for Updating of the Essential Drug List (2006) (Alphabet order): Prof. Adel Foad Ramzy Prof. Adel Sadek . Prof. Aly Ahmed El Garem. Prof. Amal El Beshlawy. Prof. Ashraf Hatem. Prof. Enas Shaltot Prof. Esmat Sheba. Prof. Ez El Deen El Denshary Prof. Gaafer Ragab. Prof. Gamela Moussa. Prof. Hady Goiran . Prof. Hany Hafez. Prof. Hasen Hosny. Prof. Hedar Galeb. Prof. Hossen Kaled. Prof. Izes Gally. Prof. Khaery Abd El Dayem. Prof. Kaled Abd El Whab El Brolosy . Prof. Magdy Arafa. Prof. Magdy Amen. Prof. Mahmod Alam . Prof. Mohamed El Tawy. Prof. Mohamed Sharaf . Prof. Mohamed Nada. Prof. Omyma El Henawy. Prof. Rashad Barsom . Prof. Reda Hamza. Prof. Roshdy El Badrawy. Prof. Sheriff El Topgy. Prof. Shokry Hanter. Prof. Taha El Shewy. Prof. Yehea Abd El Whab. Prof. Zenab Ebied. Prof. Zoher Halag.

• Revision Committee : Prof. Hedar Galeb. Prof. Mamdoh Zaky. Prof. Esmat Sheba . Prof. Ez El Deen El Denshary. Prof. Zenab Ebied.

• Coordinators:

Prof. Zenab Ebied.

• Editors& Designers Dr. Heba Moustafa. Mr. Hany Kamal.

• Cover Designer : Mr. Hany Kamal.

• Under Secratory of State: Dr. Zenab Ebied..

Members of High Expert Committee for Previous Essential Drug List (Alphabet Order) Prof. Abdalla M. Molokhia. Prof. Abdel K. Hammad. Prof. Abde] M. Hussein. Prof. Ahmed Abd El-bary. Prof. Ahmed S. Geneidy. Prof. Ahmed S. Khalifa. Prof. Essam M. Khedr. Prof. Ezz Eidin El-Denshary. Prof. Foad A. Ismail. Dr. Gamila M- Moussa. Dr. Hassan Abdel Fatah. Prof. Heider Ghalib. Dr. Hosny Tammam. Prof. Hussein Sabry. Prof. Laila Abo-basha. Prof. Mohamed A. Sallam. Prof. Mohamed I- Abdalla. Prof. Mohamed M. Ragheb. Prof. Mohamed N. El-Makhzangi. Prof. Mohamed R. Awadin. Dr. M. Tayseer El-Sawi. Dr. Morad Abdel Salam. Prof. Nabil M. Omar.

Prof. Nadia M. Morsi. Prof. Nazly Gad El-Mawla. Prof. Rafeek Zaher. Prof. Ramzy H. El-Mawardy. Prof. Sadek A.Abd Alla. Prof. Soher Hashem. Dr. Samiha S. Faltas. Dr. Taha El-khoby.

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Abbreviations :

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ACE : Angiotensin Converting Enzyme Amp. : Ampoule

AV :.Atrioventricular Cap. : Capsule Cap. Soft : Soft Gelatin Capsule Carp. :Carpoule CNS : Central Nervous System CVs : Cardiovascular System DVT : Deep venous Thrombosis Ernul. : Emulsion E.d. : Eye Drops E.O. : Eye Ointment ECG : Electrocardiograph Er.drops : Ear Drops Elix. : Elixir Gmlm2 : Gram per Square meter GlT : Gastrointestinal Tract Gm. : Gram Inj. : Injection Inhal. : Inhaler IV : Intravenous 1M : Intramuscular I.Soi. : Inhaler solution I.aeros. : Inhaler aerosol Kg : Kilogram L : Liter Lot. : Lotion M.W. : Mouth wash Mg : Milligram MAol : Monoamine Oxidase Inhibitor Mmol : Millimol mg/m2 : Milligram per square meter M.wash : Mouth wash NSAIDS : Nonsteroidal anti-inflammatory drugs Oint. : Ointment P.inf. : Parentral infusion Powd. Sach. : Powder sachet P.disp. syg : Parentral disposable syringe

Powd. : Powder Syrp. : Syrup Supp. : Suppository SC : Subcutaneous Syp. : Syrup Susp. : Suspension Soap Liq. : Soap liquid Tab. : Tablet

Tab. chew. : Tablet chewable Tab. Subling : Tablet sublingual Tab. eff. : Tablet effervescent T.gel : Topical gel T.sol. : Topical solution T.saginata : Tinea Saginata TB : Tuberculosis T. spray : Topical Spray UG : Microgram UT : Urinary tract W IW : Weight per weight V N : Volume per volume

****PART 1****

(National Essential Drug List) Non-Proprietary Names (Generics)

Part 1 Table of Contents

A1 1-(G.I.T.) - Gastro-intestinal Tract Drugs--- -------------------- A2 2-(C.V.S.) - Cardiovascular System Drugs ---------------------

A4 3- (R.S.) - Respiratory System Drugs-----------------------------

A5 4- (A.) - Antiallergics Drugs------------------------------------------

A6 5- (C.N.S.) - Central Nervous System Drugs-------------------

A6 6- (Anti.I.D) - Anti-Infectious Disease Drugs-------------------

A9 7- (E.) - Endocrine System Drugs ---------------------------------

A10 8- (Gyn.) - Obstetric & Gynecology Drugs ---------------------

A11 9-(M.)- Malignancy & Immunosuppressive Drugs------------

A11 10- (N.&B.R.) Nutrition & Blood Restorative Drugs----------

A12 11- (S.M.D.) - Skeletomuscular Drugs ---------------------------

A13 12- (OPH.) Ophthalmic Preparations -----------------------------

A14 13- (E.N.T.) - Ear, Nose & Oropharynx Drugs ----------------

A16 14- (D.) - Dermatological Drugs -----------------------------------

A17 15 - (Vac.) - Vaccins & Sera ----------------------------------------

A17 16 - (Anesth.) – Anesthetics ----------------------------------------

A18 17- (Diag.) - Diagnostic & Contrast Media Drugs -----------

A18 18- Antidotes -------------------------------------------------------------

Level Dosage Concentration

1-(G.I.T.) - Gastro-intestinal Tract Drugs

(G.I.T.)-[A]-{a}-Antiemetics & Anti-nauseants (gastroprokinetics) 1 Tab. 10mg Metoclopramide 1 Inj. 10mg Metoclopramide 1 Supp. 10mg Metoclopramide 1 Tab. 10mg Domperidone 1 Syp. 1mg / 1ml Domperidone 1 Supp. 10mg, 60mg Domperidone

(G.I.T.)-[A]-{b}-Antiemetics during Cytotoxic therapy (Serotonin Antagonists) 3 Tab 8mg Ondansetron 3 Inj 4mg/2ml Ondansetron 3 Inj 5mg Tropisetron

(G.I.T.)-[B]-Peptic Ulcer Healing Drugs (Decrease

Gastric Hcl Secretion)

(G.I.T.) - [B] - {a} - Proton Pump Inhibitors 1 Cap 20mg Omeprazole 2 Inj 40mg /vial Omeprazole (G.I.T.) - [B] - {b} - H2 Receptor Antagonist 1 Inj 100mg Cimetidine 2 Tab 150mg Ranitidine 2 Tab 300mg Ranitidine

(G.I.T.) - [C] - Antacids

1 Tab. Aluminium Hydroxide Gel & Magnesium salts or comb.

1 Susp. ``

(G.I.T.) - [D] - Antidiarrhoeal Drugs (G.I.T.) - [D] - {a} - Electrolytes of Body Fluid (Restoratives)

1 Sachet Electrolytes With Glucose For Rehydration+zinc

(G.I.T.) - [D] - {b} - Intestinal Adsorbants 1 Susp. Kaolin + Pectin (G.I.T.) - [D] - {c} - Antipropulsives 1 Tab, Syp 2mg Loperamide

(G.I.T.) - [E] - Intestinal evacuants 1 Inf. Supp. Glycerol + Gelatin 1 Supp. Glycerol + Gelatin 1 Syp 65% - 120ml, 300ml Lactulose 1 Tab 12mg, 20mg Senna extract 1 Tab. 5mg Bisacodyl

(G.I.T.) - [F] - Antihaemorrhoids 1 Oint. Fluocortolone+ Lidocaine

1 Supp. Fluocortolone+ Lidocaine

1 Oint. Hydrocortisone+ Cinchocaine

1 Supp. Hydrocortisone+ Cinchocaine

A1

A2


(G.I.T.) - [F] - AntihaemorrhoidsCont. 1 Oint. Hydrocortisone+ Lidocaine 1 Supp. Hydrocortisone+ Lidocaine 1 Oint. Predisolone + Lidocaine 1 Supp. Predisolone + Lidocaine

(G.I.T.) - [G] - Colorectal (G.I.T.) - [G] - {a} - Anti-flatulents

1 Tab. Simethicone combination

(G.I.T.) - [G] - {b} - Intestinal Antiseptics 1 Cap Chloramphenicol + Streptomycin 2 Tab. 500mg Neomycin 2 Susp. 125 mg Neomycin 1 Tab. 200mg Nifuroxazide 1 Susp. 200mg Nifuroxazide

(G.I.T.) - [G] - {c} - Enema 1 Enema Sodium Phosphate

(G.I.T.) - [H] - Hepato-biliary (G.I.T.) - [H] - {a} -Liver Support

2 Tab. Silymarin containing comp.

(G.I.T.) - [H] - {b} - Cholagogues 1 Tab. Cynara & Mg sulphate comp

(G.I.T.) - [I]- Spasmolytics 1 Drop Pipenzolate + Phenobarbitone 1 Inj 1mg Atropine Sulphate 1 Tab 20mg Hyoscine Butylbromide 1 Supp 10mg Hyoscine Butylbromide 1 Tab 100mg Mepeverine 1 Tab 135mg Mepeverine 1 Susp. 10mg Mepeverine

2-(C.V.S.) - Cardiovascular System Drugs

(C.V.S.) - [A] - Cardiac Inotropics (C.V.S.) - [A] - {a} - Cardiac Glycosids

2 Drops. 50 mcgm/ml Digoxin 2 Tab. 0.25 mg Digoxin 3 Amp 250 mg Oubain

(C.V.S.) - [A] - {b} - Other Stimulants 3 Inj 40 mg / ml Dopamine Hcl 3 Inj 250 ml/20ml vial Dobutamine 3 Inj 200 mcgm / ml Isoprenaline

(C.V.S.) - [B] - Antiarrhythmatics 2 Inj 150 mg Amiodarone

A3

Level Dosage Concentration (C.V.S.) - [B] - Antiarrhythmatics Cont.

2 Tab 200 mg Quinidine Sulphate 2 Inj 20 mg /ml Lidocaine 2 Tab 80 mg Verapamil 2 Inj 5 mg Verapamil

(C.V.S.) - [C] - Antihypertensives (C.V.S.) - [C] - {a} - Sympatholytics and Vasodilatores

1 Tab 250 mg Alpha-Methyl Dopa 2 Tab 0.15mg Clonidine

1 Tab Reserpine + Dihydroergocristine + Clopamide 3 Inj 10 mg / ml Sodium Nitroprusside 2 Tab 1 mg Prazosin

(C.V.S.) - [C] - {b} - Angiontensin Converting enzyme Inhibitors ACE inhibitors

2 Tab 25 mg Captopril 2 Tab 50/25 mg Captopril+ Hydrochlorothiazide

(C.V.S.) - [C] - {c} - Selective Angiontensin II inhibitors 3 Tab 25 mg Losartan 3 Tab 80, 160 mg Valsartan

(C.V.S.) - [C] - {d} - Calcium Antagonist 1 Cap 10,20 mg Nifedipine 1 Tab 60 mg Diltiazem

(C.V.S.) - [C] - {e} - Beta - Adrenoreceptor Blockers 1 Tab 50 mg Atenolol 1 Tab 10, 40 mg Propranolol

(C.V.S.) - [D] - Anti-anginal (C.V.S.) - [D] - {a} - Short Acting Nitrates

1 Sub.Tab 5 mg Isosorbide Dinitrate 2 Tab 10 mg Isosorbide Dinitrate 1 Sub.Tab 0.5 mg Glyceryl Trinitrate (Nitroglycerin) 2 Inj 5 mg/ml Glyceryl Trinitrate (Nitroglycerin)

(C.V.S.) - [D] - {b} - Long Acting Nitrates 2 Cap 2.5 mg Glyceryl Trinitrate (Nitroglycerin)S.R. 2 Cap 20 mg Isosorbide Dinitrate S.R.

(C.V.S.) - [E] - Antihyperlipaedemics 2 Tab 200 mg Bezafibrate 2 Tab 300mg, 600 mg Gemfibrozil 2 Tab 10mg, 20 mg Atorvastatin

(C.V.S.) - [F] - Anti-aggrigants 1 Tab 75mg, 150 mg Acetylsalicylic acid (Microencapsulated)

(C.V.S.) -[G] - Thrombolytics 3 Vial 1500000 IU Streptokinase

A4�


(C.V.S.) -[H] - Anticoagulants 2�Inj 5000 IU Glyceryl Trinitrate (Nitroglycerin) 2 Inj 25000 IU Glyceryl Trinitrate (Nitroglycerin) 2 Inj 5000 IU Heparin Calcium 2 Inj 20000 IU Heparin Calcium 2 Tab 50 mg Phenindione 2 Tab 1mg Warfarin 2 Tab 3mg Warfarin 2 Tab 5 mg Warfarin 3 Inj 20 mg/2ml Enoxaparin Sodium 3 Inj 80 mg/2ml Enoxaparin Sodium

(C.V.S.) - [I] - Diuretics (C.V.S.) - [I] - {a} - Potassium- Sparing Drugs�

2 Tab 25 mg Spironolactone 2 Tab 100 mg Spironolactone

Sparing Drugs- Potassium- {a} -] I [-.) S.V.C ( 1 Tab 25 mg Hydrochlorothiazide 1 Tab Hydrochlorothiazide+ Amiloride

(C.V.S.) - [I] - {c} - Osmotic Diuretics�

2 Inj 10%, 20 % Mannitol

Loop Diuretics- {d} -] I [-.) S.V.C (��

2 Tab 40 mg Frusemide 2 Inj 10 mg / ml Frusemide

( C.V.S.) - [J] - Antihypotensives 1 Tab 2.5mg Midodrine 1 Drop 1% solution Midodrine

(C.V.S.) - [K] - Haemostatics 1 Tab., Inj 250mg Ethamsylate 1 Inj 1mg Phytomenadione 1 Tab 10mg Phytomenadione

3- (R.S.) - Respiratory system Drugs

(R.S.) - [A] - Bronchodilators

(R.S.) - [A] - {a} -Theophyline 2 Inj 250 mg Aminophylline 2 Tab. 300 mg SR Theophyllin Anhydrous 2 Syp 60 mg / 5 ml Theophyllin Anhydrous

(R.S.) - [B] - beta Adrenergic stimulants 2 Tab 2mg Salbutamol 2 Tab 2.5 mg Terbutaline 2 Syrup 1.5 mg Terbutaline 2 Aerosol 0.25 mg Terbutaline

A5�


(R.S.) - [C] - Inhalants 2 Aerosol 5mg/dose Sodium cromoglycate 2 Aerosol 50mcgm/dose Beclomethasone 2 Aerosol 100mcgm/dose Salbutamol

(R.S.) - [D] - Anti-tussives & Cough

Suppressants 1 Tab 40mg Clobutinol 1 Syp 20mg/2ml Clobutinol 1 Tab. 15mg/dose Dextromethorphan 1 Syp 15mg/dose Dextromethorphan

(R.S.) - [E] - Mucolytics 1 Cap 375 mg Carbocysteine 1 Syp 125 mg / 5 ml Dextromethorphan 1 Tab 30 mg Ambroxol 1 Cap 75 mg Ambroxol 1 Syrup 15, 30 mg Ambroxol 1 Drop 7.5 mg Ambroxol 1 Tab 8 mg Bromhexine 1 Elixir 4 mg Bromhexine 1 Sol 2 mg Bromhexine 1 Amp. 4 mg Bromhexine 1 Guaiphenesin

(R.S.) - [F] - Hydration

4- (A.) - Antiallergics Drugs (A.) - [A] - Antihistamines

(A) - [A] - {a} - Histamine H1 Receptor Antagonists 1 Tab 4mg Chlorpheniramine Maleate 1 Susp 2mg/5ml Chlorpheniramine Maleate 1 Tab 10mg Astemizole 2 Tab 10mg Loratadine 2 Susp 5 mg / 5 ml Loratadine 2 Syp Dexamethasone + Chlorpheniramine 1 Syp 5mg / 5 ml Promethazine 2 Inj 25mg/2ml Promethazine 1 syp. 5mg/5ml Cetirizine 1 Tab 10mg Cetirizine 1 Cap Dimethindene

(A.) - [B] - Adrenergic Receptor Stimulant 1 Inj 1mg/ml Adrenalin

(A.) - [C] - Glucocorticoids 2 Tab. 0.5 mg Dexamethasone 2 Susp. 0.5 mg Dexamethasone

1 Inj 100 mg Hydrocortisone Sodium Succinate


(A.) - [C] - Glucocorticoids Cont. 2 Tab 5 mg Prednisolone 2 Tab 0.1mg Fludrocortisone 2 Amp. 7mg/2ml Betamethasone 2 Vial 40mg Triamcinolone

5- (C.N.S.) - Central Nervous System Grugs (C.N.S.) - [A] - Hypnotics, Sedatives & Anxiolytics

2 Tab 30mg Phenobarbitone 2 Syp 15mg/5ml Phenobarbitone 2 Tab 2mg Diazepam 2 Inj 10mg Diazepam

(C.N.S.) - [B] - Drugs in Psychosis & Neurosis (C.N.S.) - [B] - {a} - Anti-psychotics & anxiolytics

2 Tab 25mg, 100mg Chlorpromazine 2 Inj 50mg Chlorpromazine 2 Inj 5mg/ml Haloperidol

(C.N.S.) - [C] - Antidepressants 2 Tab 10mg, 25mg Imipramine 2 Tab 10mg, 25mg Amitriptyline 2 Tab 25mg Clomipramine 2 Tab 400 mg Lithium Carbonate

(C.N.S.) - [D] - Antiparkinsonian Drug (C.N.S.) - [D] - {a} - Antimuscarinic Drugs

2 Tab 2mg Benzatropine Mesylate

(C.N.S.) - [D] - {b} - dopaminergic Drugs 2 Tab Carbidopa + Levodopa

(C.N.S.) - [E] - Antiepileptics 2 Tab. 100mg Carbazepin 2 Syp. 100mg Carbazepin 2 Cap 50mg, 100mg Phenytoin 2 Syp 50mg Phenytoin 2 Tab 150mg Valproic acid 2 syp 20% Valproic acid 2 Tab. 200mg Sodium Valproate 2 Syp. 200mg Sodium Valproate 2 Tab 0.5mg, 2mg Clonazepam

6- (Anti.I.D) - Anti-Infectious Disease Drugs

(Anti.I.D.) - [A] - Antibacterial Drugs (Anti.I.D.) - [A] - {a} - Antibiotics (Anti.I.D.) - [A] - {a} - 1.Long Acting Penicillin

1 Inj 1,200,000 U Penicillin G Benzathine 1 Inj 400,000 U Penicillin G procaine

A6


(Anti.I.D.) - [A] - {a} - 2.Short Acting Penicillin 1 Inj 1,000,000 U Benzyl Penicillin G Sodium

(Anti.I.D.) - [A] - {a} - 3.Oral Penicillin 1 Tab. 250 mg/dose Phenoxymethyl Penicillin Potassium 1 Susp. 250 mg/dose Phenoxymethyl Penicillin Potassium 1 Tab. 250 mg Phenoxymethyl Penicillin Sodium 1 Susp. 250 mg Phenoxymethyl Penicillin Sodium

(Anti.I.D.) - [A] - {a} - 4.Broad Spectrum Semisyenthetic Penicillin 1 Cap. 250/ 500/ Igm Amoxicillin 1 Inj. 250/ 500/ Igm Amoxicillin 1 Susp 125/ 250mg Amoxicillin 3 Inj 1gm Piperacillin

(Anti.I.D.) - [A] - {a} -5.Cephalosporines 1 Cap 250mg Cefadroxil 1 Cap 500mg Cefadroxil 1 Susp 125mg Cefadroxil 1 Susp 250 mg Cefadroxil 3 Inj 500 mg Cefoperazone 3 Inj Igm Cefoperazone 3 Inj 500mg Cefotaxime 3 Inj 1gm Cefotaxime 3 Inj 1gm / vial Ceftazidime

(Anti.I.D.) - [A] - {a} - 6.Aminoglycosides 2 Inj 20/40/80 mg Gentamycin

(Anti.I.D.) - [A] - {a} - 7.Macrolides 1 Tab 250mg Erythromycin 1 Susp. 200mg/5 ml Erythromycin 1 Cap 250 mg Clarithromycin 1 Cap 500mg Clarithromycin

(Anti.I.D.) - [A] - {a} - 8.Tetracyclines 1 Cap 250 mg Tetracycline 1 Cap 100mg Doxycycline

(Anti.I.D.) - [A] - {a} - 9.Chloramphenicol 2 Inj 1mg Chloramphenicol 2 Cap 250mg Chloramphenicol 2 Cap 500 mg Chloramphenicol

(Anti.I.D.) - [A] - {a} 10.Rifampicin 2 Cap 150 mg Rifampicin 2 Cap 300 mg Rifampicin 2 Susp 200 mg/5ml Rifampicin

(Anti.I.D.) - [A] - {a} - 11.Other Anti-microbials 3 Inj 500mg Vancomycin

A7


(Anti.I.D.) - [A] - {b} -Sulphonamide 1 Susp 40mg Co-Trimoxazole 1 Susp 200 mg Co-Trimoxazole 1 Tab 80mg Co-Trimoxazole 1 Tab 400mg Co-Trimoxazole 1 Tab. Sulfamoxole + Trimethoprim 1 Susp. Sulfamoxole + Trimethoprim

(Anti.I.D.) - [A] - {c} - Fluoroquinolones 3 Tab 500mg Levofloxacin 1 Tab 500 mg Ciprofloxacin 2 Tab 400 mg Norfloxacin 2 Tab 200 mg Ofloxacin

(Anti.I.D.) - [A] - {d} - 1. Urinary Antiseptics 1 Tab 100mg Nitrofurantoin 1 Syp. 100mg Nitrofurantoin

( Anti.I.D.) - [A] - {e} - Antituberculous Drugs 2 Tab 500mg Pyrazenamide 2 Tab 500mg Ethambutol 2 Tab. 100mg Isoniazid +B6 2 Tab 150mg Rifampicin + Isoniazid 2 Tab 300mg Rifampicin + Isoniazid 2 Inj 1gm Streptomycin

(Anti.I.D.) - [A] - {f} - Antileperotic Drugs 2 Cap 100mg Clofazimine 2 Tab. 50 mg Dapsone

(Anti.I.D.) - [B] - Antiviral Drugs 2 Tab. 200, 400, 800 mg Acyclovir 2 Susp. 200, 400, 800 mg Acyclovir 2 Inj 200, 400, 800 mg Acyclovir 3 Tab 200mg Ribaverin 3 Tab 400 mg Ribaverin 3 Inj 3,5 million U Interferon

(Anti.I.D.) - [C] - Antifungal Drugs 2 Cap 500,000U Nystatin 1 Drop 100,000U / ml Nystatin 2 Tab 50 mg Fluconazole 2 Tab 150 mg Fluconazole 3 Inj 50mg / vial Amphotericin Encapsulated in liposomes 2 Tab 125 mg Griseofulvin 2 Cap Itraconazole 2 V.Cream 1% Econazole 2 V.Supp 50mg Econazole 2 V.Supp 150 mg Econazole

A8


(Anti.I.D.) - [D] - Antiprotozoal Drugs

(Anti.I.D.) - [D] - {a} - Antiamaobic& antigardiasis 1 Tab 250 mg Metronidazole 1 Susp 125 mg/5ml Metronidazole 1 Inj 5mg/ml Metronidazole 1 Tab 500 mg Metronidazole250mg+ Diloxanide Furoate250mg. 1 Tab 500 mg Tinidazole

(Anti.I.D.) - [D] - {b} - Antimalarial 1 Tab 250 mg Chloroquine Phosphate 1 Susp. 80 mg/5ml Chloroquine Phosphate 1 Inj 200 mg/5ml Chloroquine Phosphate 1 Tab 25 mg Pyrimethamine

(Anti.I.D.) - [D] - {c} - Anthelmentics 1 Tab 600 mg Praziquantel 1 Syrup 60 mg/ml Praziquantel 1 Tab 100mg Flubendazole 1 Susp 20 mg/ml Flubendazole 1 Tab 40mg Levamisole HCL 1 Susp 40mg/5ml Levamisole HCL 1 Tab. 100 mg Mebendazole 1 Susp. 100 mg Mebendazole 1 Tab 500 mg Niclosamide

(Anti.I.D.) - [E] - Antiseptics & Disinfectants 1 Ext. use 120 ml Cetrimide + Chlorhexidine

Ext. use 4 litres Chlorhexidine+Hydrogen peroxide+Propanol Ext. use 125ml Chloroxylenol Ext. use 350ml Chloroxylenol Ext. use 4 L Chloroxylenol

1 Paint 10% Povidone Iodine 1 T.sol 7.5% Povidone Iodine

1 Shampoo Povidone Iodine 1 Soap liquid Povidone Iodine 1 Shampoo 4% Povidone Iodine 1 Gauze 5% Chlorhexidine 1 Gauze Paraffin gauze Dressing 1 Paint crystal violet 1 Paint Castellani paint (Magenta paint) 1 Cream 1% Silver Sulphadiazine 1 Oint. 1% ``

7- (E.) - Endocrine System Drugs (E.) - [A] - Drugs Used in Diabetes (Anti-diabetics)

A9

Level Dosage Concentration (E.) - [A] - {a} - Insulins

2 Inj 40u/ml Human Insulins Short Acting 2 Inj 40u/ml Human Insulin intermediat Acting 2 Inj 40u/ml Human Insulin Long Acting

(E.) - [A] - {b} - Biguanide Derivatives 1 Tab 500mg Metformin

(E.) - [A] - {c} - Sulphonylurea Derivatives 1 Tab 5mg Glibenclamide

(E.) - [B] - Post. Pit. Hormones 2 Inj 5, 10 U Oxytocin 2 Tab 0.2 mg Desmopressin Acetate 2 N. spray 10mcg Desmopressin Acetate

(E.) - [C] - Glucocorticoids 1 Tab 0.5mg Dexamethasone 1 Inj 4mg/ml Dexamethasone Sodium phosphate 3 Inj 25mg Prednisolone 3 Inj 250mg Prednisolone

(E.) - [D] - Female Sex Hormones 2 Tab 5mg Norethisterone

(E.) - [E] - Contraceptives 1 Inj 150mg Medroxyprogesterone Acetate 1 Tab Ethinyl Oestradiol + Norethistrone+ Ferrous Fumarate 1 Tab Ostradiol+ Levonorgestrel

(E.) - [F] - Ovulatory Stimulants 2 Tab 50mg Clomiphen Citrate

(E.) - [G] - Thyroid Hormones 2 Tab 0.1mg Thyroxine 2 Tab Levothyroxine

(E.) - [H] - Drugs For Hyperthyrodism 2 Tab 5mg Carbimazole 2 Tab 50mg Propyl thiouracil

(E.) - [I] - Hypothalamic Hormones 3 Inj 0.05 mg / ml Octreotide

(E.) - [J] - Anterior Pituitary Hormone 2 Inj 1mg Tetracosactrin synthetic ACTH

(E.) - [K] - Antiparathyroid Hormone 2 Amp 100IU/ml Calcitonin 2 N. Spray 200IU/ml Calcitonin

8- (Gyn.) - Obstetric & Gynecology

drugs (Gyn.) - [A] - Drugs Acting On Uterus

2 Inj 0.2 mg Methyl Ergometrine Maleate 2 Inj 5, 10 U Oxytocin

A10

Level Dosage Concentration (Gyn.) - [B] - Others See Endocrine See Magnesium Sulphate

9-(M.)- Malignancy & Immunosuppressive

Drugs (M.) - [A] - Alkylating Agents

2 Tab 50mg Cylophosphamide 2 Inj 1gm Ifosfamide 2 Tab 2mg Chlorambucil 2 Inj 10mg/ml Carboplatin 2 Inj lmg/ ml Cisplatin 2 Inj 10000 MIU Asparaginase (M.) - [B] - Vinca Alkaloids and Etoposide 2 Inj lmg/ ml Vincristine Sulphate 2 Inj 1mg/ml Vinblastine Sulphate 2 Inj 20mg/ml Etoposide (M.) - [C] - Antimetabolites 2 Inj 50mg/ml Fluorouracil 2 Tab. 2.5mg Methotrexate 2 Inj. 2.5mg Methotrexate (M.) - [D] - Cytotoxic Antibiotics 2 Inj 10mg Doxorubicin 2 Inj 50mg Doxorubicin 2 Inj 2mg Mitomycin 2 Inj 10 mg Epirubicin 2 Inj 50mg Epirubicin 2 Inj 5 mg Idarubicin 2 Inj 10 mg Idarubicin (M.) - [E] - Taxanes 3 Inj 6mg/ml Paclitaxol (M.) - [F] - Hormone & Hormone Inhibitors 2 Inj 1gm Medroxyprogesterone Acetate 2 Tab 10gm Medroxyprogesterone Acetate 2 Tab 10mg Tamoxifen Citrate (M.) - [G] - Immunosuppressives 3 Cap 25mg Cyclosporin 3 Cap 50mg Cyclosporin 3 Syp 100mg/ml Cyclosporin

10- (N.&B.R.) Nutrition & Blood

Restorative Drugs (N.&B.R.) - [A] - Vitamins & Minerals

(N.& B.R.) - [A] - {a} - Vitamins 3 Soft Cap Beta-carotene

A11

Level Dosage Concentration (N.& B.R.) - [A] - {a} - Vitamins Cont.

1 Tab 5mg Folic acid 1 Cap 50,000 U Vit.A 1 Cap 100mg natural Vit. E (Tocopherol) 1 Inj 1mg Vit.B12L.A. 1 Inj 600,000 U Cholecalciferol (Vit. D3) 1 Inj 60,000 U Ergocalciferol(Vit.D2) 1 Tab. Vitamin B complex(B1, B6) 1 Syp. Vitamin B complex(B1, B6) 1 Tab. 10mg Vit. K1 (Phytomenandione) 1 Inj. 10mg Vit. K1 (Phytomenandione) 1 Tab Vitamin C (Ascorbic acid)

(N.& B.R.) - [A] - {b} - Minerals (N.& B.R.) - [A] - {b} -1.Calcium Salt

1 Tab. Vit. D + Calcium 1 Inj 10% Calcium gluconate 1 Tab 500mg Calcium carbonate

(N.& B.R.) - [A] - {b} -2.Ferrous Salt 1 Tab 200mg Ferrous fumarate 1 Syp 140mg/5ml Ferrous fumarate

(N.& B.R.) - [A] - {b} -3.Zinc Salt 1 Tab., Cap 25mg Zinc

(N.&B.R.) - [B] - Blood Restoratives (N.& B.R.) - [B] - Electrolytes for Infusion

2 Inj 15% Potassium Chloride 2 Inj 8.4% Sodium Bicarbonate 2 Inj 1/6 molar Sodium Lactate 2 Inj Ringer Lactate Solution 1 Inj 0.9% Sodium Chloride

(N.&B.R.) - [C] -Plasma Proteins & Plasma

Expanders 2 Inj 70 Dextran 2 Inj 4, 5, 20, 25, % Human Albumin

11- (S.M.D.) - Skeletomuscular Drugs

(S.M.D.) - [A] - Centeral Muscle Relaxants 1 Inj 30mg Orphenadrine 1 Tab 100mg Orphenadrine

(S.M.D.) - [B] - Peripheral Muscle

Relaxants 2 Inj 2mg/ml Pancuronium Bromide 3 Inj 10 mg/ml Atracurium 2 Inj 40 mg/2ml Gallamine Triethiodide 2 Inj 2.5 mg Neostigmine Methyl Sulphate 2 Inj 5 mg Neostigmine Methyl Sulphate

A12


(S.M.D.) - [C] - Antirrheumatics (S.M.D.) - [C] - {a} -Non steroidal Anti-inflammatory (NSAIDS)

1 Tab 300mg Acetyl salicylic acid 1 Tab 500 mg Acetyl salicylic acid 2 Tab 25 mg Diclofenac 2 Inj 75 mg Diclofenac 1 Tab 200 mg Ibuprofen 1 Tab 400mg Ibuprofen 1 Tab 25 mg Ketoprofen 1 Inj 500 mg / vial Acetylsalicylate+ Glycine

(S.M.D) - [C] - {b} - Analgesic Antipyretics 1 Sln. 120 mg/5ml Paracetamol 1 Tab 500 mg Paracetamol

(S.M.D.) - [C] - {c} -Antimigraine 2 Tab 1 mg Ergotamine Tararate 2 Tab 100mg Sumatriptan

(S.M.D.) - [D] - Antigout 2 Tab 100mg Allopurinol 2 Tab 0.5 mg Colchicine

12- (OPH.) Ophthalmic Preparations (OPH.) - [A] - Antivirals

2 E. oint 3% Acyclovir (OPH.) - [B] - Local Anaesthetics 2 E. Drops 0.4% Benoxinate (Oxybuprocaine) (OPH.) - [C] - Antibiotics 1 E. Drops 0.5% Chloramphenicol 1 E. oint Oxytetracycline+ Polymyxin (OPH.) - [D] - Steroids 2 E. Drops 0.10% Dexamethasone (OPH.) - [E] - Sulfonamides 2 E. Drops 10.00% Sulfacetamide sodium

(OPH.) - [F] - Antihistaminics And / Or

Decongestants 1 E. Drops 10% Phenylephrine 1 E. Drops 2.50% Phenylephrine

(OPH.) - [G] - Preparation for Glaucoma 2 E. Drops 0.25% Timolol 2 E. Drops 0.50% Timolol 2 E. Drops 0.30% Metipranolol 2 E. Drops 0.60% Metipranolol 2 E. Drops 0.50% Betaxolol

A13

Level Dosage Concentration (OPH.) - [H] - Miotics 2 E. Drop 1% Pilocarpine 2 E. Drop 2% Pilocarpine 2 E. Drop 3% Pilocarpine 2 E. Drop 4% Pilocarpine (OPH.) - [I] - Mydriatics 2 E. Drops 1% Atropine 2 E. oint. 1% Atropine

13- (E.N.T.) - Ear, Nose & Oropharynx

Drugs (E.N.T.) - [A] - Antibiotics

2 Ear.drops 5% chloramphenicol (E.N.T.) - [B] - Decongestants

(E.N.T.) - [B] - {a} - Sympathomimetic (Local) Drops 0.03% Oxymetazoline Drops 0.05% Oxymetazoline Drops o.5% Xylometazoline Drops 1% Xylometazoline 2 E. Drops 0.05%, 0.5% Tetrahydrozoline 2 N. Drops 0.05%, 0.5% Tetrahydrozoline

(E.N.T.) - [B] - {b} -Systemic Antihistamines 1 Tab. Clemastine 1 Syp. Clemastine 1 inj. Clemastine 1 Tab. Cyproheptadine 1 Inj. Cyproheptadine 1 Tab. Dimethindene 1 Cap. Dimethindene 1 Syp. Dimethindene 1 inj. Dimethindene 1 Cap Diphenhydramine Syp Diphenhydramine+ Menthol Tab Fexofenadine Tab. Ketotifen Drops Ketotifen Supp Ketotifen Tab. Pheniramine Syp. Pheniramine Inj. Pheniramine Syp Promethazine Tab. Loratidine Syp. Loratidine Supp. Loratidine

A14


(E.N.T.) - [B] - {b} -Systemic Antihistamines Cont. Tab. Terfenadine Syp. Terfenadine inj. Terfenadine

(E.N.T.) - [C] - Systemic Decongestants S.R.Cap Carbinoxamlne + Phenylephrine syp. Chlorpheniramine + Phenylephrine

Cap, Syp Diphenylpyraline + isopropamide + phenyl

propanolamine Tab. 60 mg Pseudo ephedrine Tab. Pseudo ephedrine +Triprolidine Syp. Pseudo ephedrine +Triprolidine Syp 8 mg Acrivastine Tab 10 mg Astemizole Tab Chloropheniramine Tab Chlorpheniramine + Caffeine Tab Chlorphenoxamine + Naphazoline Tab 10mg Cetrizine

Tab Phenyl propanolamine +caffeine

+pheneramine+mepyramine

(E.N.T.) - [D] - Decongestants

(E.N.T.) - [D] - {a} -Sympathomimetic +antihistaminic combination Drop Chlorpheniramine + Naphazoline+phenyl ephrine Drop Chlorpheniramine + Naphazoline+Cetrimide

Drop Benzalkonium chloride + Naphazoline +phenyl

Toloxamin N.Spray Dimethindene + phenylephrine+Neomycin N. Gel Dimethindene + phenylephrine+Neomycin Tab Pseudo ephedrine + Terfenadine Tab Loratidine + Pseudo ephedrine Tab Terfenadine + Paracetamol

(E.N.T.) - [D] - {b} -Perennial Nasal Allergy Spray Sod cromoglycate + Benzyl Alkonium chloride Spray Sod. Chromoglycate +xylometazole Drops 2% Sod chromoglycate only

(E.N.T.) - [D] - {c} -Corticosteroid Spray Fluticasone propionate spray 50mcg% Betamethasone 2 Aerosol Budesonide Aerosol Betamethasone dipropionate

A15


14- (D.) - Dermatological Drugs (D.) - [A] - Antibiotics

1 Oint. 1% Chloramphenicol 1 `` 3% Tetracycline 1 Cream, Oint. 2% Fucidic acid Cap 150mg Clindamycin `` 300 mg Clindamycin (D.) - [B] - sulphonamides 1 Cream 1% Silver sulphadiazine (D.) - [C] - Local antifungals 1 Powder Econazole 1 Cream 1% Clotrimazole (D.) - [D] - Antiviral 2 Cream 5% Acyclovir (D.) - [E] - Antiparasites 1 Lotion 25% Benzyl Benzoate 1 Cream, Gel 10% Benzyl Benzoate 1 Cream, Gel 25% Benzyl Benzoate

2 Cream, Lotion,

Oint. 2.50% Permethrin

2 Cream, Lotion,

Oint. 5% Permethrin

2 Shampoo 1% Permethrin (D.) - [F] - Corticosteroids 2 Cream, Oint. 0.05% Betamethasone 2 Cream 0.1% Betamethasone 1 Cream 1% Hydrocortisone (D.) - [G] - Keratolytic 2 Cream, Lotion coal tar+cade oil+Arechis oil+oleyl alc (D.) - [H] - Protective and Soothing agents 1 Oint 20% Zinc Oxide 1 Cream Dexapanthenol 1 Oint. Jojoba oil + Zinc oxide (D.) - [I] - Local antipruritic 1 Cream Crotamiton (D.) - [J] - Local acne 1 Lotion Erythromycin+zinc acetate 1 Gel Benzoyl peroxide (D.) - [K] - Antiseptic & Disinfectants 1 Paint 10% Povidone Iodine 1 T.sol 7.5% Povidone Iodine 1 Shampoo Povidone Iodine 1 Soap liquid Povidone Iodine 1 Shampoo 4% Povidone Iodine

A16


15 - (Vac.) - Vaccins & Sera

(Vac.) - [A] - Serums & Immunoglobulins 2 Inj Anti-D (Rho) Immunoglobulins 1 Inj Anti-Measles Immunoglobulins 1 Inj Anti-Parotitis Immunoglobulins 1 Inj Anti-Parotitis Gammaglobulins 1 Inj Anti-Rabies Serum 1 Inj Anti-Scorpion Serum 1 Inj Anti-Snake Venom Serum Polyvalent 1 Inj Anti-Tetanus Immunoglobulins 1 Inj Diphtheria Antitoxin 1 Inj Gas-Gangrene Antitoxin (Polyvalent) 2 Inj Human Normal Immunoglobulins (vac.) - [B] - Vaccines 1 Inj Antl- Rabies Vaccine 1 Inj Bacillus Calmette Guerin (BCG) Vaccine 1 Inj Cholera Vibrios Organisms 1 Inj Diphtheria + Tetanus Toxoids 1 Inj Diphtheria + Tetanus Toxoids + Pertussis Vaccine 1 Inj Hepatitis B Vaccine (RecombinantDNA) 1 Inj Influenza Vaccine 1 Inj Measles Virus Vaccine 1 Inj Mumps + Measles + Rubella Virus Vaccine 1 Inj Poliomyeltis Vaccine 1 Inj Tetanus Toxoid 1 Inj Typhoid Vaccine 1 Inj Typhoid - Paratyphoid A&B+ Tetanus 1 Inj Yellow Fever Vaccine 1 Inj Tuberculin 2 Inj Hepatitis A vaccines 2 Inj Rubella Vaccine 2 Inj Poliomyelitis Vaccine ( inactivated ) 2 Inj Meningococcal Polysaccharide Vaccine 2 Inj Factor VIII Human anti-hemophilia Factor 3 Inj Hyperimmunoglobulins Hepatitis HB

(vac.) - [C] - Botulism

16 - (Anesth.) - Anesthetics (Anesth.) - [A] - Local

(Anesth.) - [A] - {a} - Parentral

2 Inj 0.25mg Bupivacine 2 Inj 0.5 mg Bupivacine 2 Inj 2% Lidocaine 2 Inj Lidocaine2%+Adrenalin 5mcgm/ml

A17

Level Dosage Concentration (Anesth.) - [A] - {b} - Surface

1 Gel 2% Lidocaine 1 Oint 5% Lidocaine 2 Spray Ethyl Chloride (Anesth.) - [B] - General

(Anesth.) - [B] - {a} - Parentral 2 Inj 50mg/ml Ketamine 2 Inj 0.5,1gm Thiopentone Sodium 2 Inj 0.05 mg/ml Fentanyl 2 Inj 5mg, 15 mg / ml Midazolam 2 Inj 200 mg/20ml Propofol

(Anesth.) - [B] - {b} - Inhalation 2 Liquid Halothane 2 Liquid Isoflurane 2 Cylinder Nitrous Oxide Gas 1 Cylinder Oxygen Gas (Anesth.) - [C] - Narcotic Analgesic 2 Inj 2mg/ml Butorphenol 2 Inj 10, 20mg Morphine 2 Inj 50, 100mg Pethedine 2 Tab. 50mg Tramadol 2 Inj 50mg Tramadol

17- (Diag.) - Diagnostic & Contrast

Media Drugs 2 Oral Powder Barium Sulphate 2 Inj Diatrizoate Meglumine 2 Inj Iodised Oil 2 Inj Iopamidol 2 Inj Fluorescin

18- Antidotes

2 Inj 500mg Desferrioxamine Mesilate 2 Inj 50mg/ml Dimercaprol Mesilate 2 Inj 0.1mg/ml Fulumazenil 2 Inj 10mg Nalorphine 2 Inj 400mcmg/ml Naloxone Hcl 2 Cap 250gm Penicillamine 1 Powder 25gm Activated Charcoal 1 Syp 30mg/1ml Ipecacunha 1 Inj 1mg Atropine 2 Tab 250mg DL Methionine 2 Inj 400mcgm Methylthionium Chloride 2 Inj 40mg/kg Sodium Calcium Edetate 2 Inj 30mg/ml Sodium Nitrite 2 Inj 25mg/ml Sodium Thiosulphate 2 Inj 10mg/ml Protamine sulphate

A18

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EGYPT Ministry of Health & Population (MOHP) Central Administration of Pharmaceutical Affairs (CAPA) Technical Research and Training Department (TRTD) �

nedlg national essential drug list &guidelines · foreword: the first essential drug list and...

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