neoantigen prediction infographic

ACE ImmunoID TM Neoantigen Prediction: At-a-glance Ready to accelerate your cancer vaccine development? To learn more, contact us at [email protected] 101-003-A CLIA Validated Augmented Whole Exome & Transcriptome >8,000 Biomedically relevant genes Across 2-Week Turnaround 200x Coverage Matched Tumor/ Normal Analysis 50 ng minimum sample input Custom Bioinformatics Reporting: • Neoantigen prediction • Tumor mutational burden • Comprehensive tumor profiling • HLA-typing • MHC binding prediction Exome* 97% Sensitivity 98% Specificity 97% Sensitivity Transcriptome* ACE ImmunoID is an analytically-validated whole exome and transcriptome sequencing platform using matched tumor and normal samples, developed for use with our RUO neoantigen prediction analysis pipeline. With optimized processes and dedicated project management support, Personalis offers a one-stop solution for immuno-oncology research and clinical trials. * At 10% mutant allele frequencies for small variants ‡ 22/23 experimentally-validated neoantigens correctly predicted 96% Sensitivity Neoantigen Prediction‡

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Page 1: Neoantigen Prediction Infographic

ACE ImmunoIDTM Neoantigen Prediction: At-a-glance

Ready to accelerate your cancer vaccine development? To learn more, contact us at [email protected] 101-003-A

CLIA Validated

Augmented Whole Exome & Transcriptome

>8,000 Biomedically relevant genes

Across

2-WeekTurnaround

200x Coverage

Matched Tumor/NormalAnalysis

50 ng minimum sample input

Custom Bioinformatics Reporting:

• Neoantigen prediction• Tumor mutational burden• Comprehensive tumor profiling• HLA-typing • MHC binding prediction

Exome*

97%Sensitivity

98%Specificity

97%Sensitivity

Transcriptome*

ACE ImmunoID is an analytically-validated whole exome and transcriptome sequencing platform using matched tumor and normal samples, developed for use with our RUO neoantigen prediction analysis pipeline. With optimized processes and dedicated project management support, Personalis o�ers a one-stop solution for immuno-oncology research and clinical trials.

* At 10% mutant allele frequencies for small variants‡ 22/23 experimentally-validated neoantigens correctly predicted

96% SensitivityNeoantigen Prediction‡

Augmented Whole 2-Week Exome & Transcriptome Turnaround … · ACE ImmunoIDTM Neoantigen Prediction: At-a-glance Ready to accelerate your cancer vaccine development? To learn more,

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