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Page 1: No Slide Title - SEC.gov | HOME...Alcon AMO B&L $1,586 $307 $461 Ophthalmic Pharmaceuticals* Contact Lens Care Alcon Allergan B&L $1,356 $1,000 $468 Alcon AMO B&L $339 $295 $1,100

1

Alcon, Inc.

Page 2: No Slide Title - SEC.gov | HOME...Alcon AMO B&L $1,586 $307 $461 Ophthalmic Pharmaceuticals* Contact Lens Care Alcon Allergan B&L $1,356 $1,000 $468 Alcon AMO B&L $339 $295 $1,100

Safe Harbor StatementStatements contained in this presentation that are forward-looking are based oncurrent expectations that are subject to a number of uncertainties and risks, andactual results may differ materially. Alcon does not undertake any obligation toupdate any of the forward looking statements or forward looking information.Although Alcon believes that these statements are based on reasonableassumptions within the bounds of its knowledge of its businesses andoperations, there are a number of factors that may cause actual results to differfrom these statements. Factors that might cause these differences include, butare not limited to, the uncertainty of market acceptance of our products by theworldwide medical community; uncertainty of clinical trial results for expandedFDA approval submissions for our current products and initial approval of ourproducts under development; product liability claims; manufacturing issues; andrisks inherent in international transactions. For additional factors, which couldcause actual results to differ from expectations, reference is made to the periodicreports filed by the company with the Securities and Exchange Commissionunder the Securities Exchange Act of 1934 as amended. Additional informationabout risk factors also can be found in the Company’s Annual Report filed withthe SEC on Form 20-F, under the heading “Risk Factors” and in other documentsalso filed with the SEC. All these documents are available publicly and uponrequest from the Alcon Investor Relations Department at 817-551-8805 orwww.alconinc.com

2

Page 3: No Slide Title - SEC.gov | HOME...Alcon AMO B&L $1,586 $307 $461 Ophthalmic Pharmaceuticals* Contact Lens Care Alcon Allergan B&L $1,356 $1,000 $468 Alcon AMO B&L $339 $295 $1,100

Investment Dynamics

3

World’s LeadingWorld’s LeadingEye Care CompanyEye Care Company

Large & GrowingLarge & GrowingMarketsMarkets

InnovationInnovationand Researchand Research

Global ReachGlobal Reach

MarketMarketLeadershipLeadership

FinancialFinancialPerformancePerformance

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Investment Dynamics

4

World’s LeadingWorld’s LeadingEye Care CompanyEye Care Company

Large & GrowingLarge & GrowingMarketsMarkets

InnovationInnovationand Researchand Research

Global ReachGlobal Reach

MarketMarketLeadershipLeadership

FinancialFinancialPerformancePerformance

Page 5: No Slide Title - SEC.gov | HOME...Alcon AMO B&L $1,586 $307 $461 Ophthalmic Pharmaceuticals* Contact Lens Care Alcon Allergan B&L $1,356 $1,000 $468 Alcon AMO B&L $339 $295 $1,100

2003

$12.5

$6.8

$1.8

$3.4

OphthalmicPharmaceuticals* Contact

Lens Care

Otic Pharma

OphthalmicSurgical

$0.5

Large Growing Market

$9.0

Otic Pharma

$1.9

$3.7

$0.6

OphthalmicPharmaceuticals*

OphthalmicSurgical

NasalPharma

ContactLens Care

2006

$15.6

$0.4

+ 25%*Includes OTC Tears, Allergy and Vitamins

5

(Dollars in Billions)

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171282

248327

470

674

237195

2000 2010 2020 2030More Developed Less Developed

Markets - Favorable Demographics

Population age 65 plus

6

(Millions of people. Source: United Nations)

419522

707

956

+14% +39% +65%

+32% +90% +171%

+25%

+69%

+128%

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Investment Dynamics

7

World’s LeadingWorld’s LeadingEye Care CompanyEye Care Company

Large & GrowingLarge & GrowingMarketsMarkets

InnovationInnovationand Researchand Research

Global ReachGlobal Reach

MarketMarketLeadershipLeadership

FinancialFinancialPerformancePerformance

Page 8: No Slide Title - SEC.gov | HOME...Alcon AMO B&L $1,586 $307 $461 Ophthalmic Pharmaceuticals* Contact Lens Care Alcon Allergan B&L $1,356 $1,000 $468 Alcon AMO B&L $339 $295 $1,100

Global Reach

8

Alcon Headquarter Offices Alcon Research FacilitiesAlcon Manufacturing PlantAlcon Operating Company

•5 Research Centers•14 Manufacturing Plants•70 Operating Companies•40 Physician Training Centers•12,000 Employees

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Investment Dynamics

9

World’s LeadingWorld’s LeadingEye Care CompanyEye Care Company

Large & GrowingLarge & GrowingMarketsMarkets

InnovationInnovationand Researchand Research

Global ReachGlobal Reach

MarketMarketLeadershipLeadership

FinancialFinancialPerformancePerformance

Page 10: No Slide Title - SEC.gov | HOME...Alcon AMO B&L $1,586 $307 $461 Ophthalmic Pharmaceuticals* Contact Lens Care Alcon Allergan B&L $1,356 $1,000 $468 Alcon AMO B&L $339 $295 $1,100

Competitive Leadership(US $ Millions) 2003 Sales Results

OphthalmicSurgical

Alcon AMO B&L

$1,586

$307$461

OphthalmicPharmaceuticals*

ContactLens Care

Alcon Allergan B&L

$1,356

$1,000

$468

Alcon AMO B&L

$339$295

$499$1,100

Pfizer

*Includes OTC Tears, Allergy and Vitamins for consistency with competition; excludes Otic pharmaceuticals

Merck

$644

10

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Competitive Leadership

Surgical47% Global Share

#1 Cataract#1 Vitreoretinal#2 Refractive

Pharmaceutical20% Global Share

Contact Lens Care19% Global Share

#2 Soft Lens Care #1 Allergy#1 Anti-infective#1 Anti-inflammatory#1 Combination#1 Generics#2 Artificial Tears

2003 Market Shares

(Individual therapeutic categories represent US market shares)

11

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Investment Dynamics

12

World’s LeadingWorld’s LeadingEye Care CompanyEye Care Company

Large & GrowingLarge & GrowingMarketsMarkets

InnovationInnovationand Researchand Research

Global ReachGlobal Reach

MarketMarketLeadershipLeadership

FinancialFinancialPerformancePerformance

Page 13: No Slide Title - SEC.gov | HOME...Alcon AMO B&L $1,586 $307 $461 Ophthalmic Pharmaceuticals* Contact Lens Care Alcon Allergan B&L $1,356 $1,000 $468 Alcon AMO B&L $339 $295 $1,100

Stable Sales Growth

1978 1983 1988 1993 1998 2003

$110 Million

$3.4 Billion•CAGR = 15% for last 25 years

•Steady, predictable long-term sales growth

•96% of 2003 sales eye related

13

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Balanced Sales Growth

1999 2000 2001 2002 2003

$2,401$2,554

$2,748

48%48%

49%49%

48%

31% 33% 33% 34% 36%

21% 19% 18% 17% 16%

(US $ Millions)

Pharmaceutical

Surgical

Consumer

CAGR1999 to 2003

8.1%

13.8%

2.6%

9.1%$3,009

14

$3,407

Page 15: No Slide Title - SEC.gov | HOME...Alcon AMO B&L $1,586 $307 $461 Ophthalmic Pharmaceuticals* Contact Lens Care Alcon Allergan B&L $1,356 $1,000 $468 Alcon AMO B&L $339 $295 $1,100

Balanced Sales Growth

1999 2000 2001 2002 2003

$2,401$2,554

$2,748

48%48%

49%49%

48%

31% 33% 33% 34% 36%

21% 19% 18% 17% 16%

(US $ Millions)

Pharmaceutical

Surgical

Consumer

10.2%

20.1%

6.4%

13.2%$3,009

15

4.6%

17.0%

3.9%

9.0%$3,407

2003 vs. 2002Reported w/o FX

(Sales growth excluding the effect of foreign currency fluctuations has been presented to give investors amore accurate measure of underlying growth in the business.)

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Leveraging Global Operations

(US $ Millions - Reported Numbers)

16

$2,748$3,009

$3,407

2002 20032001

$589$704

$879

Sales Operating Income

2002 20032001

+9.5%+13.2%

+19.5%

+24.9%

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Turning Profits into Strong Cash Flow

17

$316

$467

$595

2002 20032001

$394

$575

$740

Net Earnings Free Cash Flow

2002 20032001

+47.8%+27.4% +45.6%

+28.8%

(US $ Millions - Reported Numbers)(Free Cash Flow = Net cash from operating activities less net cash from investing activities. Free cash flowpresented as a more appropriate measure for investors to gauge the Company’s ability to generate cash.)

543

-149

394

701

-126

575

915

-175

740

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Investment Dynamics

18

World’s LeadingWorld’s LeadingEye Care CompanyEye Care Company

Large & GrowingLarge & GrowingMarketsMarkets

InnovationInnovationand Researchand Research

Global ReachGlobal Reach

MarketMarketLeadershipLeadership

FinancialFinancialPerformancePerformance

Page 19: No Slide Title - SEC.gov | HOME...Alcon AMO B&L $1,586 $307 $461 Ophthalmic Pharmaceuticals* Contact Lens Care Alcon Allergan B&L $1,356 $1,000 $468 Alcon AMO B&L $339 $295 $1,100

R&D Investment

(US $ Millions)

19

$290$324

$350

2002 20032001

Planned investmentof $2 billion over thenext five years

10.3%10.8%

10.6%

As a Percent of Sales

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2003 New Product Launches

Systane® Tears

CustomCornea®

Vigamox™

Infiniti™ Vision System

AcrySof® Natural

CiproDex* Otic

Q1 Q2 Q3 Q4

20

*Cipro is a registered trademark and licensed from Bayer AG

Page 21: No Slide Title - SEC.gov | HOME...Alcon AMO B&L $1,586 $307 $461 Ophthalmic Pharmaceuticals* Contact Lens Care Alcon Allergan B&L $1,356 $1,000 $468 Alcon AMO B&L $339 $295 $1,100

1.0

1.5

2.0

2.5

3.0

3.5

4.0

4.5

5.0

Apr-03

May-03

Jun-03

Jul-03 Aug-03

Sep-03

Oct-03

Nov-03

Dec-03

Jan-04

5.0

7.0

9.0

11.0

13.0

15.0

17.0

19.0

21.0

SystaneTears Franchise

Systane ®

Share

Systane® - Share Performance

1.2

4.617.8

19.6

FranchiseShare

21

(US market share for Systane and Alcon total tears franchise)

Page 22: No Slide Title - SEC.gov | HOME...Alcon AMO B&L $1,586 $307 $461 Ophthalmic Pharmaceuticals* Contact Lens Care Alcon Allergan B&L $1,356 $1,000 $468 Alcon AMO B&L $339 $295 $1,100

0.0

2.0

4.0

6.0

8.0

10.0

12.0

14.0

May-03Jun-03 Jul-03 Aug-03Sep-03 Oct-03 Nov-03Dec-03 Jan-045.0

10.0

15.0

20.0

Vigamox Franchise0.3

11.819.6

22.4

VigamoxShare

FranchiseShare

All Prescribers

22

VigamoxTM - Share Performance

(US market share for Vigamox and Alcon total branded anti-infective franchise)

Page 23: No Slide Title - SEC.gov | HOME...Alcon AMO B&L $1,586 $307 $461 Ophthalmic Pharmaceuticals* Contact Lens Care Alcon Allergan B&L $1,356 $1,000 $468 Alcon AMO B&L $339 $295 $1,100

0%

20%

40%

60%

80%

100%

Jul-03 Aug-03 Sep-03 Oct-03 Nov-03 Dec-03 Jan-04Vigamox Ciloxan

% ofFluoroquinolone

FranchiseAll Prescribers

27%37% 43%

23

47%49% 49%

52%

Vigamox� Conversion Trend

(US conversion trend for Vigamox and Ciloxan)

Page 24: No Slide Title - SEC.gov | HOME...Alcon AMO B&L $1,586 $307 $461 Ophthalmic Pharmaceuticals* Contact Lens Care Alcon Allergan B&L $1,356 $1,000 $468 Alcon AMO B&L $339 $295 $1,100

15.1

17.8

22.7

24.723.5

17.8

10.0

15.0

20.0

25.0

Feb Mar April May Jun Jul Aug Sep Oct Nov Dec Jan

Rolling 12 2002 Rolling 12 2003

Otic Franchise - Share PerformanceMarket

Share %

24

All Prescribers

(US market share for CiproDex and Cipro HC combined)

Page 25: No Slide Title - SEC.gov | HOME...Alcon AMO B&L $1,586 $307 $461 Ophthalmic Pharmaceuticals* Contact Lens Care Alcon Allergan B&L $1,356 $1,000 $468 Alcon AMO B&L $339 $295 $1,100

40.042.3

45.648.6

30.0

40.0

50.0

60.0

2000 2001 2002 2003

AcrySof® Share PerformanceMarket

Share %

25

(US market share for all Acrysof intraocular lenses)

Page 26: No Slide Title - SEC.gov | HOME...Alcon AMO B&L $1,586 $307 $461 Ophthalmic Pharmaceuticals* Contact Lens Care Alcon Allergan B&L $1,356 $1,000 $468 Alcon AMO B&L $339 $295 $1,100

Pharmaceutical R&D Pipeline

26

2004 2005 2006+ StatusPatanol® QDTrav/tim ComboBrimonidine/PolyquadRETAANE™

Patanol® Nasal15(S)-HETE (Dry Eye)Moxi/DexNepafenac

FiledFiledPhase IIIPhase IIIPhase IIIPhase IIIPre-ClinicalPhase III

Approval targets are for U.S. regulatory approvals

2006+ indicates expected approval in 2006 or beyond.

Page 27: No Slide Title - SEC.gov | HOME...Alcon AMO B&L $1,586 $307 $461 Ophthalmic Pharmaceuticals* Contact Lens Care Alcon Allergan B&L $1,356 $1,000 $468 Alcon AMO B&L $339 $295 $1,100

Surgical/Consumer R&D Pipeline

27

2004 2005 2006+ StatusAcrySert® DeviceCustomCornea® Astig.CustomCornea® Hyper.AcrySof® Natural ToricAcrySof® ReSTOR®

New ViscoelasticAcrySof® Phakic IOLNew Vit/Ret SystemStableyzTM Irrigating Sol.

Systane® Single UseSystane® Next Gen.New CLC Solution

FiledFiledAdvancedAdvancedAdvancedAdvancedEarlyEarlyActive

AdvancedAdvancedEarly

Approval targets are for U.S. regulatory approvals

2006+ indicates expected approval in 2006 or beyond.

Page 28: No Slide Title - SEC.gov | HOME...Alcon AMO B&L $1,586 $307 $461 Ophthalmic Pharmaceuticals* Contact Lens Care Alcon Allergan B&L $1,356 $1,000 $468 Alcon AMO B&L $339 $295 $1,100

*Investigational device currently in USclinical trials

• Compound is anangiostatic cortisene

• Inhibits the growth ofabnormal blood vessels

• Applied to the back of theeye via a curved, blunt-tipped cannula

• Requires administrationonly twice a year

• Projected Q4 2004 filing

RETAANE� 15mg Depot

28

Page 29: No Slide Title - SEC.gov | HOME...Alcon AMO B&L $1,586 $307 $461 Ophthalmic Pharmaceuticals* Contact Lens Care Alcon Allergan B&L $1,356 $1,000 $468 Alcon AMO B&L $339 $295 $1,100

RETAANE� Clinical Results

73%79%88%

47%53%70%

0%20%40%60%80%

100%

RETAANE 15 mg Placebo

Stable* or Improved Vision - All Lesions

* Less than 3 lines of vision loss

% ofEyes

6 Monthp=0.0799

12 Monthp=0.0323

24 Monthp=0.0347

29

Page 30: No Slide Title - SEC.gov | HOME...Alcon AMO B&L $1,586 $307 $461 Ophthalmic Pharmaceuticals* Contact Lens Care Alcon Allergan B&L $1,356 $1,000 $468 Alcon AMO B&L $339 $295 $1,100

80%84%92%

42%50%65%

0%20%40%60%80%

100%

RETAANE 15 mg Placebo

Stable* or Improved Vision - Predominantly Classic Lesions

* Less than 3 lines of vision loss

% ofEyes

6 Monthp=0.0209

12 Monthp=0.0100

24 Monthp=0.0058

30

RETAANE� Clinical Results

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*Investigational device currently in USclinical trials

AcrySof® ReSTOR® IOL

• Optical vs. mechanicalaccommodation

• Apodized diffractive/refractive design

• Balances near anddistance light energywhen pupil is small

• Increases distance lightenergy as pupil diameterincreases

• Projected Q3 2004 filing

31

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20/60

20/50

20/40

20/30

20/25

20/20

Binocular 120-180 Days Postoperative

AcrySof® ReSTOR® Clinical Results

Near and Distance Visual Acuity

-0.10

0.10.20.30.40.50.6

ReStor (n=125) Control (n=42)

Mea

n lo

gMar

VA

Uncorrected NearVision

UncorrectedDistance Vision

20/15

32

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Visual Disturbances

0

1

2

3

4

5

6

7

Mea

n R

atin

gs

ReStor Monofocal

Gla

re/F

lare

Nig

ht V

isio

n

Col

orPe

rcep

tion

Hal

os

Dis

tort

edN

ear V

isio

n

Dis

tort

edFa

r Vis

ion

Blu

rred

Nea

rVi

sion

Blu

rred

Far

Visi

on

Dou

ble

Visi

on

33

AcrySof® ReSTOR® Clinical Results

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Spectacle Wear - Near and Distant VisionHow much of the time do you wear glasses for seeing

objects close at hand or at a distance?

0

20

40

60

80

100

None Some None Some

% S

ubje

cts

ReStorControl

Near Vision Distance Vision

34

AcrySof® ReSTOR® Clinical Results

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Strategic Sales Growth Drivers

35

New Products

Global MarketExpansion

MarketShare Gains

AgingPopulations

Target SalesGrowth 8–10%

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RevenueDrivers

Margin

Drivers

• Aging populations• Global market expansion• Market share gains• New products

• Leverage infrastructure• Debt reduction• Tax rate improvements

EPS 1.5-2X Sales Growth

Target

36

Strategic Sales Growth Drivers

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37

Alcon, Inc.