nrsa presentation - maria murray

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Applying for the NRSA F Series Grants (NIH) Individual Predoctoral NRSA Ruth L. Kirschstein Na9onal Research Service Awards Maria Murray Naviga9ng the Grant Conference 2/1/2013

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Grant Conference Day, 1 Feb. 2013

TRANSCRIPT

Applying  for  the  NRSA    F  Series  Grants  (NIH)    Individual  Predoctoral  NRSA  Ruth  L.  Kirschstein  Na9onal  Research  Service  Awards    Maria  Murray  Naviga9ng  the  Grant  Conference  2/1/2013  

Reasons  to  apply  • Grant  wri9ng  experience  is  valuable  • Great  award/honor  on  your  CV  •  $$$$$  • Bioengineering  department  gives  $3000  bonus  to  winning  students  •  Includes  funding  for  conference  travel,  lab  supplies  • Having  your  own  grant  money  gives  you  some  freedom   2

Kirschstein-­‐NRSA  pre-­‐doctoral  fellowships  (F31s)  Compe9ng  applica9ons,  awards,  and  success  rates    

Source: NIH

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R01-­‐Equivalent  grants,  New  (Type  1)    Success  rates,  by  career  stage  of  inves9gator    

NRSA Success Rate

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Source: NIH

Three  types  of  Individual  Predoctoral  NRSAs  • F30:    for  MD/PhD  and  other  CDs  • F31:    to  promote  Diversity  • F31:    for  Disserta9on  research  related  to  par9cular  ins9tutes  of  NIH    

In  addi9on,  there  are  Ins9tu9onal  NRSAs  which  are  distributed  by  departments   5

F30  MD/PhD,  VMD/PhD,  etc.  •  Up  to  6  years  of  support,  excluding  other  NRSA  (e.g.,  MSTP  or  other  TG)  support  

•  Ideal  9me  to  apply:    upon  picking  thesis  lab  •  Note  that  not  all  ins9tutes  par9cipate;  check  the  list  to  see  if  any  are  relevant  to  your  research  

•  Deadlines:  4/8,  8/8,  12/8  •  Deadlines  are  when  the  grant  needs  to  be  to  the  Ins9tute  

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F30  Participating  Institutes  •  Na9onal  Cancer  Ins9tute  (NCI)  •  Na9onal  Heart,  Lung,  and  Blood  Ins9tute  (NHLBI)  •  Na9onal  Ins9tute  on  Aging  (NIA)  •  Na9onal  Ins9tute  on  Alcohol  Abuse  and  Alcoholism  (NIAAA)  •  Na9onal  Ins9tute  on  Deafness  and  Other  Communica9on  Disorders  (NIDCD)  •  Na9onal  Ins9tute  on  Dental  and  Craniofacial  Research  (NIDCR)  •  Na9onal  Ins9tute  of  Diabetes  and  Diges9ve  and  Kidney  Diseases  (NIDDK)  •  Na9onal  Ins9tute  on  Drug  Abuse  (NIDA)  •  Na9onal  Ins9tute  of  Environmental  Health  Sciences  (NIEHS)  •  Na9onal  Ins9tute  of  Mental  Health  (NIMH)  

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F31  Diversity  •  Up  to  5  years  of  support,  excluding  other  NRSA  support  (from  training  grants)  

•  Ideal  9me  to  apply:    once  you  have  iden9fied  your  research  interests,  can  be  as  early  as  your  first  year    

•  Virtually  all  NIH  ins9tutes  par9cipate  •  Deadlines:  4/8,  8/8,  12/8  

•  Deadlines  are  when  the  grant  needs  to  be  to  the  Ins9tute  

Eligibility  can  be  determined  on  the  announcement  website:  h?p://grants.nih.gov/grants/guide/pa-­‐files/PA-­‐11-­‐112.html  

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F31  Diversity  Participating  Institutes  

•  Na9onal  Cancer  Ins9tute  (NCI)  •  Na9onal  Eye  Ins9tute  (NEI)  •  Na9onal  Heart,  Lung,  and  Blood  Ins9tute  (NHLBI)  •  Na9onal  Human  Genome  Research  Ins9tute  (NHGRI)  •  Na9onal  Ins9tute  on  Aging  (NIA)  •  Na9onal  Ins9tute  on  Alcohol  Abuse  and  Alcoholism  (NIAAA)  •  Na9onal  Ins9tute  of  Allergy  and  Infec9ous  Diseases  (NIAID)  •  Na9onal  Ins9tute  of  Arthri9s  and  Musculoskeletal  and  Skin  Diseases  (NIAMS)  •  Na9onal  Ins9tute  of  Biomedical  Imaging  and  Bioengineering  (NIBIB)  •  Eunice  Kennedy  Shriver  Na9onal  Ins9tute  of  Child  Health  and  Human  Development  (NICHD)  •  Na9onal  Ins9tute  on  Deafness  and  Other  Communica9on  Disorders  (NIDCD)  •  Na9onal  Ins9tute  on  Dental  and  Craniofacial  Research  (NIDCR)  •  Na9onal  Ins9tute  of  Diabetes  and  Diges9ve  and  Kidney  Diseases  (NIDDK)  •  Na9onal  Ins9tute  on  Drug  Abuse  (NIDA)  •  Na9onal  Ins9tute  of  Environmental  Health  Sciences  (NIEHS)  •  Na9onal  Ins9tute  of  General  Medical  Sciences  (NIGMS)  •  Na9onal  Ins9tute  of  Mental  Health  (NIMH)  •  Na9onal  Ins9tute  of  Neurological  Disorders  and  Stroke  (NINDS)  •  Na9onal  Ins9tute  of  Nursing  Research  (NINR)  •  Na9onal  Center  for  Complementary  and  Alterna9ve  Medicine  (NCCAM)  

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F31  Dissertation    •  Up  to  5  years  of  support    •  Ideal  9me  to  apply:    aaer  star9ng  disserta9on  research  •  Note  that  not  all  ins9tutes  par9cipate;  check  the  list  to  see  if  any  are  relevant  to  your  research    

•  Deadlines:  4/8,  8/8,  12/8  •  Deadlines  are  when  the  grant  needs  to  be  to  the  Ins9tute    

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F31  Dissertation  Participating  Institutes  

•  Na9onal  Cancer  Ins9tute  (NCI)  •  Na9onal  Ins9tute  on  Aging  (NIA)  •  Na9onal  Ins9tute  on  Alcohol  Abuse  and  Alcoholism  (NIAAA)  •  Na9onal  Ins9tute  on  Deafness  and  Other  Communica9on  Disorders  (NIDCD)  

•  Na9onal  Ins9tute  on  Dental  and  Craniofacial  Research  (NIDCR)  •  Na9onal  Ins9tute  on  Drug  Abuse  (NIDA)  •  Na9onal  Ins9tute  of  Mental  Health  (NIMH)  •  Na9onal  Ins9tute  of  Neurological  Disorders  and  Stroke  (NINDS)  •  Na9onal  Center  for  Complementary  and  Alterna9ve  Medicine  (NCCAM)  (  Will  no  longer  par9cipate  aaer  May  7,  2012)    

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Application  Info  &  Resources  •  F  Kiosk:  hdp://grants.nih.gov/training/F_files_nrsa.htm    Select  appropriate  F30  or  F31  program  announcement  here  •  SF424  (R&R):  hdp://grants.nih.gov/grants/funding/424/index.htm    •  Individual  Fellowship  Applica9on  Guide    

•  Grant  Officer  •  William  Burns  (SEAS)  

•  [email protected]  •  Marianne  Williams  (BGS)  

•  [email protected]  

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General  •  All  done  via  eRA  Commons  of  Grants.gov  

• CONTACT    YOUR  GRANTS  OFFICER    •  Grants  officer  will  give  you  your  log  on  info  • Will  tell  you  your  actual  due  date  • Will  be  your  best  friend  during  this  process  J  

•  Note  that  YOU  are  the  PI  •  Your  mentor  is  the  Senior/Key  Person  1  

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Identifying  the  institute:    

•  Determine  which  ins9tute(s)  of  NIH  is  the  best  fit  for  your  project  (discuss  this  with  your  PI)  

•  Contact  the  fellowship  program  officer  at  the  ins9tute(s)  by  phone  to  discuss  your  proposal  and  how  it  might  fit  with  the  ins9tute’s  scien9fic  goals;  see  numbers  on  p.  I-­‐3  of  the  Applica9on  Guide  

•  Prepare  a  cover  leder  to  be  submided  with  your  proposal  that  refers  to  the  conversa9on  and  the  program  officer  by  name  (part  of  “Other  Adachments”)  

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“Measure  twice,  cut  once”  Make  sure  your  work  is  a  

good  fit  for  the  Ins9tute  and  its  mission  

Submission  checklist  

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q Cover  Le?er  q Abstract  q Specific  Aims  q Research  Strategy  q Respec9ve  Contribu9ons  q Selec9on  of  Sponsor  and  Ins9tu9on  q Responsible  Conduct  of  Research  q Goals  for  Fellowship  Training  and  Career  q Ac9vi9es  Planned  Under    This  Award  q Doctoral  Disserta9on  and  Other  Research  Experience  q Sponsor(s)  and  Co-­‐Sponsor(s)  q Biographical  Sketch  q Project  Narra9ve  q Applica9ons  for  Concurrent  Support  (when  applicable)  q Introduc9on  to  Resubmission  or  Revision  Applica9on  (when  applicable)  

Handy  Table:  hdp://grants.nih.gov/grants/forms_page_limits.htm  

SpeciQic  Aims  •  Lay  out  your  hypothesis  and  what  you  are  going  to  do  •  Challenge:  Scope.  Make  sure  what  you  are  proposing  is  reasonable  in  the  amount  of  9me  you  have  (2-­‐3  years)  

•  Page  limit:  1  

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Research  Strategy  Plan    •  6  page  limit,  including  figures,  charts,  tables,  and  diagrams:  combine  sec9ons  before  uploading  to  monitor  length  •  Pay  close  aden9on  to  instruc9ons  on  font,  headers  (none),  page  numbers  (none),  etc.  •  SF424  Page  I-­‐110  •  GET  HELP:  Advisor,  Commidee,  Labmates,  PI,  Naviga9ng  the  Grant  Fellows  

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Respective  Contributions  

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•  Who  came  up  with  what    •  Page  limit:  1  

•  Sample  This  proposal  is  an  extension  of  my  candidacy  exam.  I  am  primarily  responsible  for  the  ideas  and  experiments  outlined  in  this  document.  Through  discussions  with  my  sponsor,  Dr.  __________,  I  was  able  to  focus  my  hypothesis  and  refine  my  experimental  approach  to  maximize  feasibility.  I  prepared  this  document  independently  but  consulted  with  Dr.  ____  for  sugges9ons  before  finalizing  the  proposal.  Figure  2  is  the  work  of  a  former  undergraduate  student,  ____  .  I  will  perform  the  described  experiments  independently.  I  will  seek  guidance  from  Dr.  ____  when  interpre9ng  data  and  troubleshoo9ng  experiments.  

Biosketch    •  See  samples  online  –  This  is  mine  

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Grades  and  GRE  scores  Other  scores  if  applicable  (MCAT)  

Selection  of  Sponsor  or  Institution  •  Why  Penn  is  awesome.    •  I  wrote:    SELECTION  OF  SPONSOR  AND  INSTITUTION    I  selected  to  adend  the  University  of  Pennsylvania  to  study  for  my  Ph.D.  because  of  the  fantas9c  reputa9on  of  the  bioengineering  department.  The  University  of  Pennsylvania  has  many  resources  available  to  make  good  research  possible  –  physical  resources  like  the  atomic  force  microscope  that  I  plan  to  use  in  my  experiments,  as  well  as  human  resources.  The  professors  at  Penn  are  leaders  in  their  fields,  and  are  willing  to  collaborate  with  and  help  students  in  order  to  produce  quality  research.  Penn  has  a  strong  core  of  faculty  studying  mechanotransduc9on  –  my  field  of  interest  (Paul  Janmey,  Chris  Chen,  Dennis  Discher,  Dan  Hammer,  Rick  Assoian,  Rebecca  Wells).  Paul  Janmey  is  a  good  mentor  because  in  addi9on  to  being  a  well-­‐respected  leader  in  the  field,  he  also  cares  about  his  students  and  takes  the  9me  to  train  them.  The  situa9on  that  I  have  found  at  Penn  will  provide  me  with  the  educa9on  that  I  need  to  further  pursue  my  goals.     20

Goals  for  Fellowship  Training  and  Career  •  Page  of  what  you  want  to  do  

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Career

Short & Long Term

Skills to gain

Activities  Planned  Under  Award  

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Doctoral  Disseration  and  Other  Research  Experience  

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Sponsor’s  Statement  •  Instruc9ons  on  website  

•  Sec9ons  •  Research  Support  Available  (Standard  NIH  Format)  •  Sponsor’s  Previous  Trainees/Fellows  •  Training  Plan,  Environment,  Facili9es  •  Number  of  Fellows/Trainees  to  be  Supervised  During  Fellowship  •  Applicant’s  Qualifica9ons  and  Poten9al  For  Reseach  Career  

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Project  Narrative  •  Brief  descrip9on  of  your  project  for  a  lay  person  

Example:  As  the  body  ages,  the  arteries  become  s9ffer  and  this  increased  s9ffness  is  a  risk  factor  for  cardiovascular  disease.  In  this  proposal,  I  will  look  at  the  changes  in  the  endothelial  cells  (the  cells  that  line  the  blood  vessel)  under  both  soa  and  s9ff  condi9ons  in  order  to  see  if  the  change  in  the  s9ffness  of  the  arteries  causes  changes  in  the  func9on  of  the  endothelial  layer.  This  is  important  because  it  could  help  to  explain  why  the  s9ffening  in  the  arteries  causes  increased  cardiovascular  risk.       25

Other  Components  •  Responsible  Conduct  in  Research  (Medical  School  Form)  •  Human  Subjects  (Y/N):  From  Mentor  •  Vertebrate  Animals  (Y/N):  From  Mentor  •  Resource  Sharing  Plan:  From  Mentor  

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Letters  of  Recommendation  (3-­‐5)  

•  NOT  mentor/sponsor  (since  s/he  writes  statement  about  your  qualifica9ons  in  the  grant)  •  Usually  the  graduate  group  chair,  CD  head  and/or  program  chair  (if  applicable),  rota9on  advisor,  thesis  commidee  member,  or  faculty  research  collaborator    • Must  use  fellowship-­‐specific  form  and  be  submided  electronically    hdps://commons.era.nih.gov/commons/reference/submitRefereeInforma9on.jsp    

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Steps  to  Take  •  ≥30  days  prior  to  deadline:  •  Grants  officer  •  Think  about  your  proposal,  talk  to  Naviga9ng  the  Grant  about  getng  a  mentor  

•  Get  3  referees  on  board;  make  sure  they  use  the  required  form  

•  ≥  10  days  prior  to  deadline:  •  Complete  your  forms  &  adachments  •  Have  your  advisor  review  applica9on  

•  ≥  3  days  prior  to  deadline:      •  Everything  in  final  form  for  Univ.  review  

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Good  Luck!!      Questions?  

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