omega-3 dha nutrition & application - nutrition sc bangkok seminar 18 sep 2008 by plpek

Omega 3 DHA Nutrition and Application

Presented by

Nutrition SC Thailand Customer Seminar Landmark Hotel, Bangkok

18-19 September 2008

Poh Len Pek GM Sales & Marketing


1. About Nu-Mega Ingredients • DHA from Albacore Tuna Oil • Production Process

2. Importance of Omega-3s for Health • The Science on Health Benefits • Recommended Daily Intake & Consumer Nutrition Gap

3. Omega-3 Fortified Foods Market Trends • Global - Launches, Top Product Categories, Regions • Trends in Asia Pacific and Thailand • Products and Health Claims (Foods & Supplements)

4. Applications • Key Considerations • Critical Success Factors • Examples - Fortified Foods, Beverage and Supplements

5. Nu-Mega DHA Advantage


Nu-Mega Ingredients 100% Australian Company

ASX-Listed parent – Clover Corporation

20 Years history 1988-1999 2003-2007 2008->

• Clover Corp Started in 1988 Listed ASX 1999

• JV with Heinz = Nu-Mega Lipids

• Clover Corp JV with Food Spectrum = Nu-Mega Ingredients

• Clover Corp as Nu-Mega Production & QA

• Food Spectrum as Nu-Mega sales, marketing & distribution

• Nu-Mega Ingredients became 100% subsidiary Clover Corp (Nov 07)

• New Brisbane Application Lab (Jun08)

• New GM Sales & Marketing (Jun08)

• New Clover Corp Innovation Manager (Jul08) • Clover Corp JV with

Future Food Ingredients = Nu-Soya sales & marketing

2006->


Nu-Mega Ingredients

4

- 3 major Australian Cities

Applications, R&D

Nu-Soya Production

Sales

Sales & Marketing Logistics Omega-3 Production & QA

Microencapsulation at Murray Goulburn Nutritionals plant


Nu-Mega Ingredients

• Tuna Oil Refinery in Altona, 20” from Melbourne CBD • Only process DHA tuna oil

=> OU KOSHER and HALAL certified

Head Office & Factory


Nu-Mega Ingredients • Eight Mile Plains, 40” from Brisbane CBD

• New Laboratory & Office • 8 FT and PT Technologists & Technicians

Application R&D in Brisbane


Nu-Mega Ingredients Sales Office Agents

Sales Office Manufacturing Site Agents

Chicago London

Brisbane Sydney Melbourne

Nutrition SC


Nu-Mega Ingredients Australian Customers


Nu-Mega Ingredients

9

• StarKist Samoa • In Pago Pago, American Samoa in Pacific Oceans

• Dedicated tuna cannery (950T/day) • USA No.2 Consumer Tuna brand

• Exclusive long term supply agreement

• OU Kosher certified Nu-Mega invested in equipment to process cannery by-product into crude tuna oil that is shipped to Australia.

Exclusive Crude Tuna Oil Supply


Nu-Mega Ingredients

X

http://www.fao.org/docrep/U8480E/U8480E0f.htm


Nu-Mega Ingredients

• Albacore Tuna Thunnus alalunga

11

• Tuna catch consists: • 50% Yellowfin and Albacore Tuna • 50% Skipjack/bonito

• High proportion (25%) of Albacore species underpin the consistently high DHA content (over 25%) and very high (more than 4.5:1) DHA:EPA ratios in Nu-Mega Omega-3 oils and Driphorm HiDHA powders. No other companies have access to such raw materials.

• Entrails are removed and not processed • This significantly reduces heavy metal and

other potential contaminants. • Heavy metals have never been detected in

the starting crude tuna oils since Nu-Mega began refining operations in 1998.


Nu-Mega Ingredients Tuna >25% DHA, >4.5DHA:1EPA

50% global catch


Nu-Mega Ingredients Starkist Tuna Processing

Canned Meat

Cook

Separate

Fillet

Separate

Cook

Grind

Conc-entrate

Purify

Oil Packaging

Cool

Frozen

Fish

Thaw

Heads & Viscera

Removal

Cook

Viscera Reject Fish

Scraps

To Australia

To Fish Meal Drier

Heads

To Boiler Fuel Waste Water Waste Water

Conc-entrate

Waste Water

To Boiler Fuel


Nu-Mega Ingredients Altona Tuna Oil Refining

Alkali Refining

Steam Deodorise

Packaging Filtration

Bleach clay/carbon

Soapstock/ Washings

(remove free fatty Acids/ Impurities)

Spent Bleaching Clay (remove oxidation by

products/ colour)

Driphorm Powders

Crude Tuna Oil

Bulk Oil


Nu-Mega Ingredients

ü Outcomes:

ü Low fish odour

ü Low fish taste

ü Reduction in FFA

ü Environmental contaminant reduction


Nu-Mega Ingredients

• Dichloro-Diphenyl-Trichloroethane (DDT) is the most persistent organochloride pesticide found within Nu-Mega crude tuna oil.

• Total DDT = sum of all DDT, DDE and DDD isomers

• Evaluation of first nine batches of Steam Deodorised tuna has found average reduction of Total DDT to be >75%.

• Samples of pre-deodorised and post-deodorised batch samples for the first nine batches:

• Analysed by CLF environmental residues laboratory in Germany • Results in following graph


Nu-Mega Ingredients

0

10

20

30

40

50

60 Total DDT (ppb)

Nu-Mega Tuna Oil Batch no.

Total DDT (before) Total DDT (after)

ND ND ND ND ND ND

ND = Not Detected (Below level of quantitation <5ppb)

EU MRL (10ppb)

Australian FSANZ MRL (50ppb)

EU Customer Tuna Oil spec MRL (40ppb)


Nu-Mega Ingredients CSIRO Micro-encapsulation Process at MG Nutritionals

Water

Flash Blend

Oil Phase - Tuna Oil (7005) - Emulsifiers - Antioxidants

Homogenise

Inert Gas Flushing

Spray Dry

Flash Blend Coarse Emulsion


Nu-Mega Ingredients Certifications

ü Registered Fish Exporter – Health Certificates

ü Halal Certification Authority Australia ü Islamic Coordinating Council of Australia (JAKIM)

ü Kashrut London Beth Din


1. About Nu-Mega Ingredients • DHA from Albacore Tuna Oil • Production Process & Quality Assurance





Poh Len Pek GM Sales & Marketing 21

human breast milk, tuna cod liver, mackerel, herring, salmon, sardine.

human breast milk, tuna, organ meats, mackerel, salmon, sardines eggs.


They are Important for our Health


ü COGNITIVE HEALTH Brain Development and Mental Function

ü VISION Visual Developmental, Functioning and Maintenance

ü HEART HEALTH Cardiovascular health and disease prevention/recovery


• Positive effect on rheumatic arthritis • Positive effect on asthma

ü JOINT HEALTH

Ongoing research to quantify and validate likely benefits in treatment/prevention of:

• ADHD – Attention Deficit Hyperactivity Disorder • Alzheimer’s Disease • Schizophrenia • Depression • Dyslexia • Cancer


To help communicate understandable Health messages on long chain Omega-3s, Nu-Mega became a Founding Member of 2 organizations.

The organizations educate consumers by communicating the latest science and research on long chain Omega-3s and the health outcomes

http://www.omega-3centre.com/

http://www.goedomega3.com/

http://www.omega-3centre.com/


0

100

200

300

400

500

600

Amer HA 200

3

FAO/WHO 20

03

ISSFAL 200

4

UK SACN 2004

M of Healt

h Japa

n 2005

USFDA 2005

NHMRC 2006

Aust H

F 2008

mg

LCPU

FA (E

PA +

DHA

)/day

* * Averaged across gender

Most advocate 500 mg EPA+DHA per day


*

* DHA recommendation only

0

200

400

600

800

1000

Amer HA 2003

FAO/WHO 2003

ISSFAL 2004

UK SACN 2004

M of Health Japan 2005

USFDA 2005

NHMRC 2006

Aust HF 2008

mg

LCPU

FA (E

PA +

DHA

)/day

Adults Adults with CHD Men Women Children Toddlers Infants Pregnant/lactating women

Adults with CHD: 1000 mg EPA+DHA per day


• Biochemical pathways of both Omegas share common enzymes

• But modern foods are high in Omega-6 and low in Omega-3 Substantially higher Omega-6 intake results in inefficient conversion of dietary short chain Omega-3 fatty acids (ALA)

An imbalance towards Omega-6 leads to a marked increase in dietary diseases such as cancer, heart, stroke, diabetes, arthritis, and skin disorders.

Ration-3:n-6

Australia 1 : 9 Meyer BJ et al quoted in Pacifc Lipids Conference (2003)

UK 1 : 5.7 MAFF (1997) quoted in BNF (1999)

UK 1 : 6.9 Gregory, Foster, Tyler et al (1990) quoted in BNF (1999)

USA 1 : 9.8 Kris-Etherton, Taylor, Yu-Poth et al (2000)

USA 1 : 16.7 Simonopoulos (2001)

Japan 1 : 4 Sugano and Hirohara (2000)

Japan 1 : 4.0-4.5 Okita, Yoshida, Yamamot et al (1995)

Country Reference


• International Society for the Study of Fatty Acids and Lipids (ISSFAL)

Recommends an Adequate Daily Intake for Healthy Adults a ratio of approximately 1:2 Omega-3 to Omega-6

• WHO recommendation for Infants Infants should also receive significant intakes of AA. This increases ISSFAL ratio of Omega-3 : Omega-6 up to 1:5 for infants


Global +457% increase in new Omega-3 products launched last 5 years

Asia Pacific

+203% increase in Foods, Vitamins & Supplements

Thailand

Rank 8 /13 Asian countries


Products Containing Omega-3, All Food and Non-Food FMCG Products, Global (no. of new products, Jan 2003 – Dec 2007)

Date Number of Product

Launches

2003 459 2004 809 2005 1,279 2006 2,113 2007 2,560

All FMCG Products

Poh Len Pek GM Sales & Marketing Products Containing Omega-3, All Food and Non-Food FMCG Products, Global (no. of new products, Jan 2003 – Dec 2007)

All FMCG Products Food and Non-Food


Global Regions Products Containing Omega-3, Food Products and Vitamin & Supplements, Global (% of new products, Jan 2003 – Dec 2007)

Top 10 Countries Products Containing Omega-3, Food Products and Vitamin & Supplements, Global (no. of new products, Jan 2003 – Dec 2007)


Date Number of Product

Launches

2003 114 2004 171 2005 177 2006 229 2007 346

Products Containing Omega-3, Food Products and Vitamin & Supplements, Asia Pacific (no. of new products, Jan 2003 – Dec 2007)


Countries – Asia Pacific Products Containing Omega-3, Food Products and Vitamin & Supplements, Global (no. of new products, Jan 2003 – Dec 2007)


Top 10 Categories Products Containing Omega-3, Food Products

and Vitamin & Supplements, Asia Pacific (no. of new products, Jan 2003 – Dec 2007)

Fish, Meat and Egg

Products

Baby Food Dairy

Healthcare

Sauces & Seasonings

Bakery Snacks

Meals & Meal Centres

Breakfast Cereals

Side Dishes

Top 10 Sub-Categories Products Containing Omega-3, Food Products and

Vitamin & Supplements, Global (no. of new products, Jan 2003 – Dec 2007)


Products Containing Omega-3, Food Products and Vitamin & Supplements, Thailand (no. of new products, Jan 2003 – Dec 2007)

Foods, Vitamins and Supplements


2nd Fish, Meat &

Egg Products

3rd Dairy

Bakery

Healthcare

Snacks

Meals & Meal

Centres Breakfast Cereals

All Categories Products Containing Omega-3, Food Products and Vitamin & Supplements, Thailand (% of new products, Jan 2003 – Dec 2007)


2

Poh Len Pek GM Sales & Marketing Source: AC Nielsen Data 2006-7

Categories High Performing Sub-categories

US$300m 7% growth

Rank 6th global

Rank 6th global

US$150m 1% growth

US$300m 16% growth

Milk/Cream/Substitutes Rank 3rd global

US$392m 3% growth

Probiotic Drinks Rank 10th global

US$110m 13% growth


-

200

400

600

800

1,000

1,200

Bottled Water

Functional Drinks

Fruit/Veg Juice

RTD Tea RTD Coffee Asian Specialty

Drinks

USD $M 2006 2010


http://www.gnpd.com/sinatra/gnpd/images/zoom&id=796862&pic_num=0&xOff=0&yOff=0&destWidth=391&destHeight=855&origWidth=693&origHeight=380




1. About Nu-Mega Ingredients • Omega 3 DHA from Albacore Tuna Oil • Production Process & Quality Assurance

2. Importance of Omega-3s for Health • The Science on the Health Benefits • Recommended Daily Intake & Consumer Nutrition Gap

3. Omega-3 Fortified Foods Market Trends • Global Launches, Top Product Categories, Regions • Trends in Asia Pacific and Thailand • Products and Health Claims (Foods & Supplements)




• Highest natural DHA Content (up to 26%) • Total Omega-3 content typically 34%

• Lower DHA content (8-23%) Vs Tuna Oil • Therefore cheaper than Pure Tuna Oil

• Produced from Fermentation • Highest DHA concentration (up to 43%) • Projected to grow the strongest

• Plant Source • Cheapest Source of Omega-3 • Used where Vegan option is preferred


Low • 20-40%

(Nu-Mega)

Medium • 40-70%

High • 70-90%


Source DHA:EPA ratio Status Total n-3 Typical Use Mature Mother’s milk

5:1

Tuna oil 25 to 27: 5 to 7 prized 33-37 Infant formula

Fish oil 12:18 common 33-37 Supplements

Sardine oil 14:14 common 35 Supplements

Anchovy oil 12:18 cheapest 35 Animal Feeds

Algal oil 100%DHA expensive 40 Vegan, Infant Formula


1. About Nu-Mega Ingredients • Omega 3 DHA from Albacore Tuna Oil • Production Process & Quality Assurance

2. Importance of Omega-3s for Health • The Science on the Health Benefits • Recommended Daily Intake & Consumer Nutrition Gap

3. Omega-3 Fortified Foods Market Trends • Global Launches, Top Product Categories, Regions • Trends in Asia Pacific and Thailand • Products and Health Claims (Foods & Supplements)


5. Nu-Mega DHA Application Advantage


• Minimize un-encapsulated i.e, uncoated surface or ‘free’ oil

• Good tolerance to disruption during food processing conditions

• Reduce rancidity and development of marine flavour and odour taints


D001.003 Driphorm®

LCP Oil Blend Powder

D005.010 Driphorm®

LCP 50 Powder

D304.000 Driphorm®

ARASCO® 50 Powder

D305.000 Driphorm®

DHASCO® 50 Powder


Omega-3 Addition Rate/Cost Calculator

Omega-3 Powder Min. Powder Desired LCPUFA Process Driphorm Serving

Content (mg/g) Delivery (mg/serve) Yield Addition Rate Size (g)

DHA EPA DHA EPA+DHA (%) (g/serve)

Driphorm HiDHA 50 110 23 5 100% 0.045 200


• Homogeneity of DHA

• Blending efficiency COV <10%

• Opaque Packaging

• Natural antioxidant eg Vitamin C / E


Problem N-3 Oxidation

High Surface Area Long Shelf Life Required


Product launches in Australia and Europe • Light & oxygen barrier packaging critical for success • Achieved 12 months Shelf-Life

http://www.freedomfoods.com.au/healthy-product.php?prodid=667&prodtype=1&prodcat=11&page=2&prodtitle=Omega%20Bar


Use Stabilisers

Problem Protein Precipitation

Low pH <4.6 High Temp 110°C/4 secs

Long Life Juice Supajus

Stabilizers Packaging

40mg DHA per 100ml 26.3 mg DHA per 100ml


Balance of multiple varieties of fruit Juices Stabilizer and Packaging

130mg DHA/EPA per 350ml

Boost Juice


Product launches in Australia

• Frozen + Light & Oxygen Barrier packaging critical for shelf life success • Relatively large serve size – easier to achieve higher fortification level

30mg DHA/EPA per 240g serve 180mg DHA/EPA per 130g serve


• Opaque Packaging

• Yield Loss calculation

• Dry Blending efficiency COV <10%

Australia 30mg/g serve


• Pilot Trials • Achieved 18 months frozen

shelf-life • Addition of Driphorm post-

homogenisation gave excellent sensory result

• Add at same time as flavours for best result


• Achieved 12 months ambient shelf-life of dry-blend (nitrogen headspace)

• Excellent sensory results

• Driphorm® addition no effect on hydration

• Dry blending or spray drying; Add to fluid bed


Problem Disruption of

encapsulant High Shear in the Churn

Use Anti-Churning Salts

http://www.cottoninc.com/CottonCandyPress/CottonCandyPressIssue2/images/ICE-CREAM.jpg



30mg DHA/EPA per 200g serve

30mg DHA/EPA per 90g serve Incorporate Driphorm® HiDHA® 50 into yoghurt dosing syrups



60mg DHA/EPA per 100g serve

Incorporation of Driphorm® HiDHA® 50 into pot set yoghurt Achieved 45 days refrigerated shelf life


• Incorporate Driphorm® into dosing syrups with Stabilisers

Short (60 days) shelf life of aseptic packaged syrups critical for shelf-life success of finished yoghurt

• Flavour masking of Driphorm® fortified syrups

• 45 days shelf life of yoghurt critical for shelf life success


For Children For Pregnant Women

Products launched in Australia


• Good Flavouring • Light & Oxygen Barrier

Packaging • E.g blister packaging is critical

for shelf life success • Opaque Outer Packaging • Good Oxygen barrier

capsules • Apply Driphorm for Vitamin

syrup, chewable tablets… • Apply Tuna Oil for capsules /

burstlets.


Problem Tablet

Cracking Dosage level


Extension of Driphorm®/‘MicroMax’ technology

• More elastic shear/pressure tolerant

• Specialty high amylase starch

• Exterior is hydrophilic (attracts water) and interior is hydrophobic (repels water)

• Oil is tightly bound in the starch interior - microcapsules have low surface fat.

• Modified production process

– Melt crystal structure of the starch followed by high pressure homogenization

– Break the starch chains, creating more cross linking- stronger encapsulant


• Temperature control in the leaven process. As Driphorm contains nutrients for yeast it accelerates the leaven process

• Australia 30mg/g serve


International Society for the Study of Fatty Acids and Lipids (ISSFAL) • Adequate intake per person per day: 500mg LCPUFA (DHA + EPA) • 10% of ISSFAL recommendation: 50mg DHA + EPA

• 50% Australians consume less than 100 mg per day • 4 slices of bread gives > 65% increase • Important for all age groups for different reasons


Nu-Mega offers

• Accelerated shelf life testing capability

• In-house retained DHA testing capability


Opportunity

ID Trials Product

Development Launch

Marketing

• Market Analysis • Concept

samples • Working with

Regulatory bodies

• Familiar with TFDA guidelines

• Scientific evidence

• Formula development

• Formula Costing

• Concept sample proofs

• Packaging design

• Trouble shoot

• In-house stability tests (inc DHA analysis)

• Joint partnership in shelf life analysis

• Up-scaling to pilot plants

• Production trials • Trouble shoot

• Consumer Education Promotion

• DHA-in-mind logo


Driphorm® LCP Oils Infant - 23% Tuna Oil - WPC+Glucose Encapsulant

Driphorm ® LCP 50 - Includes Martek AA - Sodium Caseinate+Glucose+Patented MRP

Encapsulation Process

Driphorm® HiDHA® 50 - 48% Tuna Oil - Sodium Caseinate+Glucose+Patented MRP

Encapsulation Process

Driphorm® ThermoMAX 50 - 50% Tuna Oil - Starch+Sodium Caseinate+Maltodextrin

Encapsulant+Patented MRP Encapsulation Process

Thank you

omega-3 dha nutrition & application - nutrition sc bangkok seminar 18 sep 2008 by plpek

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