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Product of the Month HumaCount 30 TS and HumaCount 60 TS May/ June 2013 hier Produkt mit orangem Hinter- grund einsetzen

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Page 1: P-LCC

Product of the Month

HumaCount 30TS and HumaCount 60TS

May/ June 2013

hier Bild mit

orangem Hinter-

grund einsetzen

hier Produkt mit

orangem Hinter-

grund einsetzen

hier Bild mit oran-

gem Hintergrund

einsetzen

Page 2: P-LCC

The new features and validation data

HumaPower (REF 18965/12) and Human SolarCharge

(REF 18965/14), a 12Volt battery system charged by a solar

panel to operate the HumaCount 30/60TS systems.

Advantages

no conversion loss - using 12 Volt HumaPower

remote setup

UPS included, of course!

The Solar panels generate DC power, being stored easily in

batteries (12 Volt). Power supplies use 220 Volt and convert

this AC-voltage to 12Volt DC voltage for the instrument.

Conventional systems with inverter lose energy in 2 ways –

converting 12Volt to 220Volt and then converting 220Volt to 12Volt.

The HumaPower system uses just 12 Volt directly applying it to the HumaCount 30/60TS.

HumaPower can be charged by solar power, a generator or by ordinary mains.

New Parameters

• P-LCC Platelet large cell concentration

• P-LCR Platelet large cell ratio

P-LCR and P-LCC are important parameters to investigate

thrombocytopenia. Specifications are described as below.

P-LCC = platelets larger than 12 fl and smaller than 30fl.

P-LCR = P-LCC/PLT

(PLT = total number of platelets, PL= platelets, fL= femtoliter)

Product of the Month

HumaCount 30TS and HumaCount 60TS

Page 3: P-LCC

Following four parameters are now displayed simultaneously

• RDW-SD Red Cell Distribution width

• RDW-CV Red Cell Distribution width (absolute)

• PDW-SD Platelet Distribution width

• PDW-CV Platelet Distribution width (absolute)

RDW-SD and RDW-CV are important parameters for

anisocytosis.

The distribution width of the erythrocyte or platelet population

derived from the histogram at 20% of peak

xDW-SD = RDWcal . (P2 - P1) (fl),

xDW-CV = RDWcal . 0.56* . (P2 - P1) / (P2 + P1) *correction factor

Market requirements on 3-Part-Diff haematology analyzers

• Routine labs:

WBC , RBC, PLT, HGB, HCT, MCV

Current status is 18 parameters

> We offer 22 parameters

• Blood banks:

PLT, RBC, WBC, HGB

> We offer 22 parameters

• Veterinarians:

Software settings for common animals are available on HumaCount 30TS

> We offer settings for: cow, horse, dog and cat including validation studies!

• Paediatric clinics:

Small sample volume

> We offer a pre-dilution mode with 25µl sample volume

Product of the Month

HumaCount 30TS and HumaCount 60TS

Page 4: P-LCC

HumaCount 30TS/60TS vs. CellDyn 3700 comparative study

59 samples were analyzed in this study. K2-EDTA Vacutainer tubes (BD) were used. All samples run on

the reference Cell-Dyn 3700 instrument in closed-tube mode within 2 hours as routine laboratory ana-

lysis using the open-tube mode on HumaCount 30TS within 4-6 hours.

The primary parameters (WBC, RBC, HGB, MCV, PLT and MPV) were measured and reported by Huma-

Count 30TS correlated well with the Cell-Dyn 3700 results. In most of the cases, slopes of statistical re-

gression were close to 1.

Most of the calculated CBC parameter (HCT, MCH, and PCT) correlation coefficients were around or over

90%.

Granulocytes measured by HumaCount 30TS were correlated with the sum of neutrophils, eosinophils

and basophils reported by Cell-Dyn 3700 reference instrument. Correlation coefficients for lymphocyte

and granulocyte absolute counts were over 98%, while percentages were over 97%. Correlation coeffici-

ent for monocyte absolute count was over 90%, while percentage was over 80%.

Clinical evaluation summary:

“The instrument provides excellent values of reproducibility on CBC and primary parameters, and very

low carryover for CBC parameters.”

Product of the Month

HumaCount 30TS and HumaCount 60TS