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    Pediatric NutritionAssessment: The

    Dietitians Toolbox

    Caro lin e Steele, MS, RD, CSP, IBCLC

    Manager, Clinical Nutrition & Lactation [email protected]

    Childrens Hospital of Orange County

    Orange, CA

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    Objectives

    1. Calculate calorie, protein, and fluid needs

    for pediatric patients of various ages.

    2. Evaluate anthropometric measurements in

    the pediatric patient.3. Determine appropriate use of various

    infant, pediatric, and adult enteral

    formulas.

    4. Discuss parenteral nutrition in the pediatric

    patient.

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    Pediatric Nutrition Assessment

    nthropometrics

    iochemical Data

    linical Data

    iet History

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    Definitions

    Infant: Birth to 1 year of age

    Neonate: Birth to 1 month

    Full Term: >37 weeks gestation

    Premature: Less than or equal to 37 weeks

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    A

    Anthropometrics

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    Growth Charts

    CDC 2000 growth charts

    Pre-term infants-Fenton

    Down Syndrome

    Cerebral Palsy

    Turner Syndrome

    Prader Willi Syndrome

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    Weight

    Infants-obtained nude

    Children-minimal clothing, no shoes

    Used to assess pts acute nutrition status

    %Ideal wt-wt/length or height

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    Infant Weight Classifications

    LBW:

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    X X34 week infant

    5# (LBW)

    AGA

    Term (40 week) infant

    5# (LBW)

    SGA

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    Length/Height

    Infants-length, measuring board

    Children-stadiometers

    Used to assess chronic

    nutrition status

    %Height age

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    Infant Linear Growth

    Preterm goals:

    1-1.75 cm/week until 3 mos. adjusted age

    0.5 cm/week from 3-6 mos. adjusted age

    0.3 cm/week from 6-12 mos. adjusted age

    Term goals:

    0.66-0.75 cm/week for first 6 months

    0.5 cm/week from 6-12 months

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    Alternative Measurements

    Alternative measurements for children with special

    health care needs

    Arm span

    Sitting height/crown rump length

    Body segment lengths

    TSF-triceps skinfolds-indirect measure of body fat

    good for longitudinal tracking

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    Head Circumference (OFC)

    Should be plotted on all infants until at least 18

    months adjusted age.

    Typically decreases ~0.5 cm during the first week

    due to contraction of extracellular fluid space.

    Preterm goals:

    0.5-1 cm/week until 3 mos. adjusted age

    0.25 cm/week from 3-6 mos. adjusted age

    Term goals:

    0.33 cm/week

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    Body Mass Index

    BMI = kg/m2

    Non invasive tool determining over/under weight

    Formula

    Wt kg divided by ht m

    2

    e.g. 50 kg/1.542= BMI 21.1

    CDC Cut-Off Points

    >85%tile-at risk for overweight

    >95%tile-overweight

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    Pediatric Nutrition

    Assessment

    Accurate heights- Why are they so

    important??

    Degree of Malnutrition

    Acute-wt/ht

    Chronic-ht/age

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    Waterlow Criteria

    Grading of nutritional status

    Acute Chronic

    Grade %Ideal wt %Ht age

    I-mild 80-90 90-95

    II-moderate 70-79 85-89

    III-severe

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    B

    Biochemical

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    C

    Clinical

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    Clinical

    Medical History

    Physical Exam

    Nutrition History

    Medications

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    D

    Diet History

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    Intake Assessment

    24 hr diet recall

    Food Records

    Food Frequency

    Calorie Count

    Nursing flow sheet

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    Nutrient Requirements

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    Fluid Requirements

    0-10 kg 100 ml/kg

    10-20 kg 100 ml/kg + 50ml/kg (over 10kg)

    >20 kg 1500 ml + 20 ml/kg (over 20kg)

    OR

    1500 cc x BSA

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    Energy Requirements

    Critically ill children stop growing & utilize the

    energy conserved by this mechanism to fuel the

    stress response

    Excessive caloric provision during acute criticalillness has no beneficial effect & may be harmful

    Although critically ill children tend not to lower

    energy needs during critical illness, in the

    chronic or convalescent phase of illness, many

    may need additional calorie for catch up

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    Approximate Energy Requirementsin Critically Ill Children

    Age in Years Est Kcal/kg/day

    0 4 100

    4

    6 906 8 80

    8 10 70

    10 12 60

    12 18 50

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    Protein Requirementsin Critically Ill Children

    Age in Years Est g pro/kg/day

    0 2 2-3

    2-13 1.5-213-18 1.5

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    Catch Up Growth Requirements

    kcal/kg/d RDA Calories Ideal Body

    for age weight

    Kcal/kg/d X kg

    Actual Weight (kg)

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    Nutrient Requirements

    Protein-RDA as a minimum

    12% of total calorie needs

    Carbohydrate-50-55% of total calorie needs

    Excess can increase RQ

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    Nutrient Requirements

    Fat-30% of total calorie needs

    3-4% EFA to prevent deficiency(3% as Linoleic, 1% alpha-linolenic)

    Vits/minerals-DRIs

    RDAs, AI, EAR and TUL

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    Nutrition Support for

    the Pediatric Patient

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    Enteral Nutrition

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    Enteral Nutrition in the Neonate

    Initiate as soon after birth as clinical and GI status allow

    Trophic feedings or GI priming

    Colostrum for oral care

    Trophic feeding

    Small volumes (~2.5-20 mL/kg/d) for 1-2 weeks

    Gut atrophy develops rapidly in preterm infants on TPN;

    feeding may promote synthesis of gut hormones days to full enteral feeding and length of hospital stay

    Yu VYH, Simmer K. In: Tsang RC et al, eds. Nutrition of the Preterm Infant: Scientific Basis and Practical Guidelines. 2nd ed. 2005:311-332.

    Kleinman RE, ed. Pediatric Nutrition Handbook. 5th ed. 2004:23-54.

    Akers S, Groh-Wargo S. In: Samour PQ, King K, eds. Handbook of Pediatric Nutrition. 3rd ed. 2005:75-106.

    Anderson DM. In: Samour PQ, King K, eds. Handbook of Pediatric Nutrition. 3rd ed. 2005:53-73.

    Wessel JJ. In: Groh-Wargo S et al, eds. Nutritional Care for High-Risk Newborns. Rev 3rd ed. 2000:321-339.

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    Gavage Feeding

    Nasogastric or orogastric

    Nonnutritive sucking during gavage feedings may

    help improve maturation of the sucking reflex and

    transition to oral feedings

    Intermittent vs continuous feedings

    Transpyloric feedings (nasoduodenal,oroduodenal, nasojejunal, orojejunal)

    Absorption of nitrogen and fat is decreased

    Yu VYH, Simmer K. In: Tsang RC et al, eds. Nutrition of the Preterm Infant: Scientific Basis and Practical Guidelines. 2nd ed. 2005:311-

    332.

    Wessel JJ. In: Groh-Wargo S et al, eds. Nutritional Care for High-Risk Newborns. Rev 3rd ed. 2000:321-339.

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    Method of Delivery

    NGT: 5F

    Continuous

    Bolus

    Gavage

    po/ng

    po 1 of 3 feedings, 2 of 3, po q 3 hrs., po ad lib

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    Nutrition Support

    Methods Enteral Support

    Acute-OG, NG, transpyloric

    Functioning gut

    Gut perfusion

    Formula selection

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    TF Administration

    Continuous

    1-2 cc/kg/hr

    Advance 1-2 cc/kg/hr q 6-12 hoursAdolescents, begin 20-25 cc/hr

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    TF Administration

    Intermittent 2-5 cc/kg/feed q 3-4 hours

    Advance 2-5 cc/kg/feed

    Infuse over 30-60 min

    Bolus

    Not used often in critical patients Infuse over 10-15 min by gravity

    Do not use in transplyoric feedings

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    What to Feed?

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    Benefits of Breast Milk

    Breast milk is BEST! Use whenever possible

    Ease of digestion

    Whey-to-casein ratio~60:40

    Low renal solute load (RSL)

    Immune-enhancing properties/antibodies

    Neurodevelopment

    Preterm infants typically unable to meet increasedcalorie/nutrient needs on breast milk alone

    Schanler RJ, Atkinson SA. In: Tsang RC et al, eds. Nutrition of the Preterm Infant: Scientific Basis and Practical Guidelines.

    2nd ed. 2005:333-356.

    Sapsford AL. In: Groh-Wargo S et al, eds. Nutritional Care for High-Risk Newborns. Rev 3rd ed. 2000:265-302.

    Groh-Wargo S. In: Groh-Wargo S et al, eds. Nutritional Care for High-Risk Newborns. Rev 3rd ed. 2000:231-263.

    F tifi ti f B t Milk f

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    Fortification of Breast Milk for

    Preterm Infants

    Human milk fortifier (HMF) For preterm infants weighing 2 kg

    Schanler RJ, Atkinson SA. In: Tsang RC et al, eds. Nutrition of the Preterm Infant: Scientific Basis and Practical Guidelines.

    2nd ed. 2005:333-356.

    Sapsford AL. In: Groh-Wargo S et al, eds. Nutritional Care for High-Risk Newborns. Rev 3rd ed. 2000:265-302.

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    Fortification of Breast Milk forPreterm Infants (contd)

    Use of nutrient-enriched discharge formulas in

    conjunction with breast milk once HMF is stopped

    may be appropriate for preterm infants ready for

    discharge

    Or for larger preterm infants who still need nutritional

    fortification

    Steele CL. Pediatric Perspectives. 2005;4(9).

    Robbins ST, Beker LT, eds. Infant Feedings: Guidelines for Preparation of Formula and Breastmilk in Health Care Facilities.2004:746-747.

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    Breast MilkTerm Infants

    Breast milk is BEST! Use whenever possible

    Term infants typically able to meet nutrient needs on

    breast milk alone unless volume restricted

    Calories may be increased in breast milk if needed due

    to poor growth, limited intake, or medical diagnoses

    HMF is NOT appropriate for term infants

    Choice of additives depends on clinical conditions and

    reason for fortification tsp formula powder/90 mL breasmilk = 22 kcal/oz

    1 tsp formula powder/90 mL breastmilk = 24 kcal/oz

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    Preterm Formulas

    Typically fed to smaller preterm infants (

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    Nutrients in Preterm Formulas

    Nutrient Preterm Formulas

    Carbohydrate

    41%-44% of total calories

    50%-60% glucose polymers (corn syrup solids)

    40%-50% lactose

    Protein11%-12% of total calories

    Whey predominate

    Fat

    44%-49% of total calories

    40%-50% MCTs

    50%-60% oil blend (including DHA and ARA)

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    Preterm Discharge Formulas

    Typically fed to larger preterm infants or as next stepformulas after preterm formula. May be used alone or in

    conjunction with BF to increase total daily calories.

    Contain higher nutrient levels than routine term

    formulas but lower levels than preterm formulas tominimize the potential for toxicity

    Standard dilution is 22 Cal/fl oz, but may be increased

    as needed

    Nutrient-enriched discharge formulas are recommended

    until 9-12 months corrected age

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    Nutrients in Discharge Formulas

    Nutrient Discharge Formulas

    Carbohydrate

    40%-42% of total calories

    50%-60% corn syrup solids

    40%-50% lactose

    Protein11% of total calories

    Whey predominate

    Fat

    47%-50% of total calories

    20%-25% MCTs

    75%-80% LCTs (including DHA and ARA)

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    Term Formulas

    Designed for term infants

    Standard dilution is 20 Cal/fl oz

    If increased energy is needed for growth or

    because of fluid restriction, may concentrate

    calories

    Nevin-Folino N, Miller M. In: Samour PQ, King K, eds. Handbook of Pediatric Nutrition. 3rd ed. 2005:499-524.

    R ti C Milk B d

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    Routine Cow MilkBased

    Term Formula

    NutrientRoutine Cow MilkBased

    Term Formulas

    Carbohydrate

    43%-45% of total calories

    100% lactose

    Protein

    8%-9% of total calories

    Milk based

    Fat48%-49% of total calories

    Oil blend (with or without DHA and ARA)

    C Milk B d F l

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    Cow MilkBased Formula

    with Added Rice Starch

    Nutrient Added Rice Starch Formulas

    Carbohydrate

    43%-45% of total calories

    Part of carbohydrate from rice starch

    Protein

    9%-10% of total calories

    Cow milk based

    Fat

    46%-49% of total calories

    Oil blend (including DHA and ARA)

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    Lactose Free

    Nutrient Lactose-Free Formulas

    Carbohydrate

    43%-44% of total calories

    No lactose

    Maltodextrin and sugar/corn syrup solids

    Protein

    8%-9% of total calories

    Cow milk based (milk-protein isolate)

    Fat

    48%-49% of total calories

    Oil blend (including DHA and ARA)

    Not appropriate for infants with galactosemia

    P ti ll H d l d

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    Partially Hydrolyzed,

    Reduced Lactose Formulas

    Nutrient Partially Hydrolyzed,Reduced Lactose Formulas

    Carbohydrate

    43%-45% of total calories

    Maltodextrin, corn syrup solids

    Lactose

    Protein

    ~9% of total calories

    Partially hydrolyzed cow milk protein

    Not hypoallergenic

    Fat46%-48% of total calories

    Oil blend (including DHA and ARA)

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    Soy-Based Formulas

    Christie L. In: Samour PQ, King K, eds. Handbook of Pediatric Nutrition. 3rd

    ed. 2005:161-180.

    Nutrient Soy-Based Formulas

    Carbohydrate 41%-42% of total calories

    Protein

    10% of total calories

    IgE-mediated hypersensitivity to milk; 14% also

    sensitive to soy

    Non-IgEmediated enterocolitis and enteropathy

    syndromes; 30%-50% also sensitive to soy

    Fat

    48%-49% of total calories

    Oil blend (including DHA and ARA)

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    Casein Hydrolysate Formulas

    Failed trial of intact formula

    GI problems/Colic

    Hypoallergenic

    Protein allergy (milk and/or soy)

    Contain protein that has been broken down to

    small peptides and free amino acids

    May or may not contain MCT

    Nevin-Folino N, Miller M. In: Samour PQ, King K, eds. Handbook of Pediatric Nutrition. 3rd ed. 2005:499-524.

    American Academy of Pediatrics. Pediatrics. 2000;106:346-349.

    Wessel JJ, Samour PQ. In: Samour PQ, King K, eds. Handbook of Pediatric Nutrition. 3rd ed. 2005:351-379.

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    Elemental/Free AA Formulas

    Elemental formulas

    Contain free amino acids

    Typically warranted after a failed trial

    of an extensively hydrolyzed formula Hypoallergenic

    MCT oil may or may not be present

    Nevin-Folino N, Miller M. In: Samour PQ, King K, eds. Handbook of Pediatric Nutrition. 3rd ed. 2005:499-524.

    Wessel JJ, Samour PQ. In: Samour PQ, King K, eds. Handbook of Pediatric Nutrition. 3rd ed. 2005:351-379.

    http://elecare.com/
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    Inborn Errors of Metabolism

    Formulated to specifically treat an inborn error of

    metabolism(s) by removing or limiting the offending

    nutrient (s)

    Many are enriched with carnitine and conditionally

    essential nutrients.

    Designed to be an adjunct in meeting the overall

    MNT of the infant-some recipes include 3-4

    formulas

    Need gram scales to measure

    for accuracy

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    Macronutrient Goals

    Calorie distribution

    40%-50% carbohydrate

    7%-11% protein

    40%-50% fat

    Akers S, Groh-Wargo S. In: Samour PQ, King K, eds. Handbook of Pediatric Nutrition. 3rd ed. 2005:75-106.

    Groh-Wargo S. In: Groh-Wargo S et al, eds. Nutritional Care for High-Risk Newborns. Rev 3rd ed. 2000:231-263.

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    Increasing Caloric Density

    Formulas typically mixed to 24-27 Cal/fl oz by adjusting amountof water added

    30 Cal/fl oz typically considered maximum

    Above 26-27 Cal/fl oz, may consider modulars to increase

    calories and/or protein

    Considerations for high-calorie formulations

    Osmolality: 450 mOsm/kg water

    pRSL:

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    Calculating Osmolality

    Use product information for osmolality on a standard

    concentration to determine osmolality of a formula of different

    caloric level

    Example

    Product literature shows a 20 Cal/fl oz infant formula has an

    osmolality of 300 mOsm/kg water

    You want to find out the osmolality of concentrating it to 27

    Cal/fl oz

    27 Cal/fl oz 20 Cal/fl oz = 1.35 (ie, 135% more

    concentrated) Multiply 300 mOsm/kg water (osmolality of 20 Cal/fl oz

    formula) by 1.35 (135% higher concentration)

    ANSWER: The 27 Cal/fl oz infant formula has

    an osmolality of ~405 mOsm/kg water

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    Calculating pRSL

    Max goal is

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    Additives

    Carbohydrate

    Protein

    Fat/CHO

    Modular Components

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    Modular Components

    Carbohydrate and Protein

    Carbohydrate

    Polycose powder

    Per tsp (~2 g powder)

    8 Cal

    1.88 g carbohydrate

    Displaces ~1.2 mL volume

    Protein

    RESOURCE Beneprotein

    Instant Protein Powder

    Per g

    3.57 Cal

    0.86 g protein

    Displaces ~0.6 mL volume

    Per tsp (1.5 g)

    5.4 Cal

    1.3 g protein

    Displaces ~1.02 mL

    volume

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    Modular ComponentsFat

    Corn oil

    8.4 Cal/mL (all from fat)

    Microlipid

    4.5 Cal/mL (0.5 g fat)

    MCT oil requires special handling and does not

    contain any EFAs 7.7 Cal/mL (all fat)

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    Toddler Formulas

    Similac 2 milk and soy

    based

    Enfagrow (formerly Next

    Step) milk and soy

    based

    Fe fortified

    Bridge gap between

    formula and milk

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    Pediatric Formulas

    Ages 1-10 yrs

    Oral supplements & TF

    Oral products higher

    in osmolality With and without Fiber

    RDA met in 950-1300 mL

    Available in 1.0 or 1.5 kcal/mL

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    Pediatric Formulas

    Ages 1-10 yrs

    Elemental

    Dipeptides

    Free AA

    LCT and/or

    MCT

    Available in 1.0and 1.5 kcal/mL

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    Adolescent Formulas

    Ages >11 yrs

    Standard/Isotonic

    +/- Fiber

    Available in 1.0,

    1.2, & 1.5

    kcal/mL

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    Parenteral Nutrition

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    Parenteral Calorie Needs

    Preterm Infants 80-105 NPC/kg/d

    Infants 70-100 NPC/kg/d

    Children 60-80 kcal/kg/d

    Adolescents 40-60 kcal/kg/d

    90% of enteral support

    Provide at least BMR/REE

    Avoid overfeeding

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    Carbohydrate

    50-55% of calories

    3.4 kcal/gm

    Maximum glucose infusion rate

    Infants 12-14 mg/kg/min

    Toddlers 10-12 mg/kg/min

    School Age 8-10 mg/kg/min

    Adolescents 6-8 mg/kg/min

    Adults 4-6 mg/kg/min

    Maximum dextrose concentration

    D12.5W maximum concentration via PIV

    D25W maximum concentration via central line

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    Excessive Calorie/CHO Provision

    Excess glucose administration increases CO2production rates & respiratory failure may be

    exacerbated

    Excess caloric administration does not spareprotein during critical illness and has shown to

    increase RQ by increasing CO2 production more

    than a high CHO diet

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    Parenteral Protein Needs

    Preterm Infants Children Adolescents

    3-4 2-3 1.5-2.5 1-2

    12-15% of total calories

    4 kcal/gm

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    Protein

    Pediatric-specific solutions for infants

    Crystalline amino acids

    Examples: Trophamine and Aminosyn PF

    Contain histidine (essential)

    Contain taurine and tyrosine (conditionally essential)

    Cysteine available as additive (essential)

    Dose 30-40 mg/g amino acids

    Carnitine (conditionally essential) may be added for infants

    not receiving enteral nutrition beyond 2 weeks 10-20 mg/kg/d

    Cox JH, Melbardis IM. In: Samour PQ, King K, eds. Handbook of Pediatric Nutrition. 3rd ed. 2005:525-557.

    Sapsford AL. In: Groh-Wargo S et al, eds. Nutritional Care for High-Risk Newborns. Rev 3rd ed. 2000:119-149.

    Aminosyn is a registered trademark of an entity unrelated to Mead Johnson & Company.

    TrophAmine is a registered trademark of an entity unrelated to Mead Johnson & Company.

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    Lipids

    Infants Children Adolescents (g/kg/d)

    0.5-3 1-2.5 1-2.5

    20% Intralipid (2 kcal/mL; 1 g = 5 mL)

    EFA 6% total kcal (0.5-1 g/kg/d for neonates) Biochemical abnormalities precede clinical symptoms

    (triene:tetraene ratio of >0.4)

    Consequences of deficiency

    Dermatitis

    Infection

    Thrombocytopenia

    FTT

    Do not exceed 60% total kcal

    In infants/small children, best infused over 24 h

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    Vitamins (MVI)

    Contents

    Vitamins C, A, D, E, B6, B12, K

    Niacin, thiamin, riboflavin, biotin, folic acid, pantothenic

    acid

    Dosage

    Infants & Children to age 10: Ped MVI 5 mL (1 vial)/day

    Preterm Infants 10 yrs: MVI-12 10 mL/day

    *

    T El t

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    Trace Elements

    Contents Zinc, manganese, copper, chromium

    Additional Zn for preterm and wounds

    Selenium & molybdenum for long-term (>30 d)

    May need to limit copper and manganese to 1-2

    doses/wk in infants with cholestasis (d bili >2)

    May need to limit selenium and chromium in infants

    with renal dysfunction

    Rao R, Georgieff M. In: Tsang RC et al, eds. Nutrition of the Preterm Infant: Scientific Basis and Practical Guidelines. 2nd ed. 2005:277-310.

    Kleinman RE, ed. Pediatric Nutrition Handbook. 5th ed. 2004:23-54.

    Cox JH, Melbardis IM. In: Samour PQ, King K, eds. Handbook of Pediatric Nutrition. 3rd ed. 2005:525-557.

    Krug SK. In: Groh-Wargo S et al, eds. Nutritional Care for High-Risk Newborns. Rev 3rd ed. 2000:151-175.

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    Minerals/Electrolytes

    Adjusted based on clinical condition

    Adjusted as needed to maintain serum levels of

    electrolytes

    Used to maintain acid-base balance

    Amounts may be limited based on their solubility(calcium and phosphorus)

    Atkinson SA, Tsang R. In: Tsang RC et al, eds. Nutrition of the Preterm Infant: Scientific Basis and Practical Guidelines. 2nd ed.

    2005:245-275.

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    What We Eat May Determine Who We

    Can Be!

    Opt imum Goal of Nutr i tion Assessment

    and Suppo rt in the Pediatr ic Pat ient?

    Facilitate wound healing & immune response

    Normal growth and development