periodontal conditions, gutka-chewing and type 2 diabetes fawad javed dds, phd karolinska...

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Periodontal conditions, gutka-chewing and type 2 diabetes Fawad Javed DDS, PhD Karolinska Institutet, Institute of Odontology, Research Department, Huddinge, SWEDEN [email protected]

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Page 1: Periodontal conditions, gutka-chewing and type 2 diabetes Fawad Javed DDS, PhD Karolinska Institutet, Institute of Odontology, Research Department, Huddinge,

Periodontal conditions, gutka-chewing and type 2 diabetes

Fawad JavedDDS, PhD

Karolinska Institutet, Institute of Odontology, Research Department, Huddinge,

SWEDEN

[email protected]

Page 2: Periodontal conditions, gutka-chewing and type 2 diabetes Fawad Javed DDS, PhD Karolinska Institutet, Institute of Odontology, Research Department, Huddinge,

February 12, [email protected] 2

What is gutka?

A form of smokeless tobacco.

Commercially available in tins and sachets.

In India, the tobacco industry recorded a growth of up to $ 500 million.

In India, gutka is popular among all socioeconomic groups.

Page 3: Periodontal conditions, gutka-chewing and type 2 diabetes Fawad Javed DDS, PhD Karolinska Institutet, Institute of Odontology, Research Department, Huddinge,

February 12, [email protected] 3

Page 4: Periodontal conditions, gutka-chewing and type 2 diabetes Fawad Javed DDS, PhD Karolinska Institutet, Institute of Odontology, Research Department, Huddinge,

February 12, [email protected] 4

Composition of gutka

GutkaAreca nut

Slaked lime

Powdered tobacco

Artificial sweeteners and fragrances

Page 5: Periodontal conditions, gutka-chewing and type 2 diabetes Fawad Javed DDS, PhD Karolinska Institutet, Institute of Odontology, Research Department, Huddinge,

February 12, [email protected] 5

How is gutka chewed?

Placed between maxillary and mandibular teeth

Lightly chewed

Held against buccal mucosa over long period

Continued to be lightly chewed and sucked

Spat or swallowed when desired

Page 6: Periodontal conditions, gutka-chewing and type 2 diabetes Fawad Javed DDS, PhD Karolinska Institutet, Institute of Odontology, Research Department, Huddinge,

February 12, [email protected] 6

Background

Association between oral cancer and gutka usage has been reported.

Periodontal conditions are severe in subjecs with type 2 diabetes (T2D).

Effect of gutka chewing on periodontal status of individuals with and without T2D are not yet documented.

Page 7: Periodontal conditions, gutka-chewing and type 2 diabetes Fawad Javed DDS, PhD Karolinska Institutet, Institute of Odontology, Research Department, Huddinge,

February 12, [email protected] 7

Page 8: Periodontal conditions, gutka-chewing and type 2 diabetes Fawad Javed DDS, PhD Karolinska Institutet, Institute of Odontology, Research Department, Huddinge,

February 12, [email protected] 8

Inclusion & Exclusion Criteria:

Inclusion Criteria:

Age 45 to 64 years Medically diagnosed type 2 diabetes (T2D) Self-reported non-diabetic individuals

Exclusion Criteria:

Edentulism Smoking Maxillary and mandibular 3rd molars Self-reported Hepatitis B and Hepatitis C Self-reported infection with Human Immunodeficiency Virus (HIV) Self-reported Acquired Immune Deficiency Syndrome (AIDS)

Page 9: Periodontal conditions, gutka-chewing and type 2 diabetes Fawad Javed DDS, PhD Karolinska Institutet, Institute of Odontology, Research Department, Huddinge,

February 12, [email protected] 9

Gutka-chewers & Non-chewers

Gutka-chewers:

Chewing at least one sachet of gutka daily for at least 12 months

Non-chewers:

Not using tobacco in any form

Page 10: Periodontal conditions, gutka-chewing and type 2 diabetes Fawad Javed DDS, PhD Karolinska Institutet, Institute of Odontology, Research Department, Huddinge,

February 12, [email protected] 10

Study participants

Individuals with T2D

29 gutka-chewers 44 non-chewers

14 males

15 females

23 males

21 females

Non-diabetic Individuals

36 gutka-chewers 42 non-chewers

17 males

19 females

22 males

20 females

Page 11: Periodontal conditions, gutka-chewing and type 2 diabetes Fawad Javed DDS, PhD Karolinska Institutet, Institute of Odontology, Research Department, Huddinge,

February 12, [email protected] 11

Material and methods

In subjects with T2D Duration of T2D

Gutka-chewers in subjects with and without T2D Age Duration of habit Daily consumption Duration of placement in oral cavity Reasons for gutka consumption RBGL

Page 12: Periodontal conditions, gutka-chewing and type 2 diabetes Fawad Javed DDS, PhD Karolinska Institutet, Institute of Odontology, Research Department, Huddinge,

February 12, [email protected] 12

Material and methods

Clinical periodontal examination PI BOP PD (4mm < 6 mm & ≥ 6 mm)

Self-perceived oral health Gingival bleeding Bad breath, i.e. halitosis Dry mouth

Page 13: Periodontal conditions, gutka-chewing and type 2 diabetes Fawad Javed DDS, PhD Karolinska Institutet, Institute of Odontology, Research Department, Huddinge,

February 12, [email protected] 13

Statistical Analysis

Performed using a software program.

Dependent variables (PI, BOP and PD [4mm < 6mm and ≥ 6mm) and independent variables were analyzed using ANOVA.

P-values < 0.05 were considered statistically significant.

Page 14: Periodontal conditions, gutka-chewing and type 2 diabetes Fawad Javed DDS, PhD Karolinska Institutet, Institute of Odontology, Research Department, Huddinge,

February 12, [email protected] 14

Page 15: Periodontal conditions, gutka-chewing and type 2 diabetes Fawad Javed DDS, PhD Karolinska Institutet, Institute of Odontology, Research Department, Huddinge,

February 12, [email protected] 15

Mean age, duration of T2D and random blood glucose levels among gutka-chewers and non-chewers in subjects with and without T2D

Page 16: Periodontal conditions, gutka-chewing and type 2 diabetes Fawad Javed DDS, PhD Karolinska Institutet, Institute of Odontology, Research Department, Huddinge,

February 12, [email protected] 16

Duration of use, placement in the mouth and daily consumption of gutka in subjects with and without T2D

Page 17: Periodontal conditions, gutka-chewing and type 2 diabetes Fawad Javed DDS, PhD Karolinska Institutet, Institute of Odontology, Research Department, Huddinge,

February 12, [email protected] 17

Periodontal conditions among gutka-chewers and non-chewers in subjects with and without T2D

Page 18: Periodontal conditions, gutka-chewing and type 2 diabetes Fawad Javed DDS, PhD Karolinska Institutet, Institute of Odontology, Research Department, Huddinge,

February 12, [email protected] 18

Oral symptoms reported by gutka-chewers and non-chewers in subjects with and without T2D

Page 19: Periodontal conditions, gutka-chewing and type 2 diabetes Fawad Javed DDS, PhD Karolinska Institutet, Institute of Odontology, Research Department, Huddinge,

February 12, [email protected] 19

Reasons for gutka use

28%

47%

17%

8%

Subjects without T2DSubjects with T2D

17%

52%

7%

24%

Page 20: Periodontal conditions, gutka-chewing and type 2 diabetes Fawad Javed DDS, PhD Karolinska Institutet, Institute of Odontology, Research Department, Huddinge,

February 12, [email protected] 20

In subjects without T2D:

Gutka-chewers have severe periodontal conditions and oral symptoms compared to non-chewers.

Conclusion

In subjects with T2D:

The severity of these variables is associated with glycemic levels

compared to gutka usage.

Page 21: Periodontal conditions, gutka-chewing and type 2 diabetes Fawad Javed DDS, PhD Karolinska Institutet, Institute of Odontology, Research Department, Huddinge,

February 12, [email protected] 21

Teachers open doors but you must enter by yourself

Page 22: Periodontal conditions, gutka-chewing and type 2 diabetes Fawad Javed DDS, PhD Karolinska Institutet, Institute of Odontology, Research Department, Huddinge,

Fawad Javed

Karolinska Institutet, Institute of Odontology, Research Department, Huddinge,

SWEDEN

[email protected]

Thank You !