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Curriculum Vitae

PERSONAL INFORMATION Pasquale Ferrante

WORK EXPERIENCE

1978–1987 Assistant Professor Microbiology and Clinical MicrobiologyUniversità degli Studi di Milano, (Italy)

1985–1986 Visiting ScientistNINCDS, NIH,, (United States)

1986–1987 Visiting ScientistThe Wistar Institute, (United States)

1988–February 2007 Director of Clinical and Biology LaboratoryFondazione Don Gnocchi, IRCCS, ONLUS, (Italy)

November 1988–October 1991 Associate Professor HygieneUniversity of Milano, (Italy)

1988–1989 Member, National Consultant CommitteeMinistry of Health, (Italy)

November 1991–October 2006 Associate Professor Microbiology and Clinical MicrobiologyUniversity of Milano, (Italy)

February 1999–October 2004 Medical chiefFondazione Don Gnocchi, IRCCS, ONLUS, (Italy)

2002–2008 Member, Evaluation CommitteeGaetano Pini Hospital, (Italy)

November 2004–June 2005 Scientific DirectorFondazione Don Gnocchi, IRCCS, ONLUS, (Italy)

19/11/14 © European Union, 2002-2014 | http://europass.cedefop.europa.eu / 26

Curriculum Vitae Pasquale Ferrante

2005–2006 Consultant, Defense CommitteeItalian Republic Senate, (Italy)

November 2006–Present Full Professor Microbiology and Clinical MicrobiologyUniversity of Milano, (Italy)

December 2007–December 2009 Medical ChiefSaint Joseph Hospital, (Italy)

June 2010–Present Scientific DirectorIstituto Clinico Città Studi, (Italy)

January 2011–Present Medical ChiefIstituto Clinico Città Studi, (Italy)

EDUCATION AND TRAINING

1975– Medical DoctorUniversity of Milano, (Italy)

1978– PhD HygieneUniversity of Milano, (Italy)

1981– PhD Infectious DiseasesUniversity of Milano, (Italy)

ADDITIONAL INFORMATION

Expertise Prof. Ferrante is full professor of Microbiology and Virology at the

Public Health-Microbiology-Virology Department, University of Milano, Italyand he is also medical and

scientific director of Istituto Clinico Città Studi,Milano.

The academic laboratory he is directing is involved in several

research projects devoted to the study of the molecular basis of various humandiseases, including:

Acute and Subacute Viral Infection of Central Nervous System

Multiple Sclerosis,

Alzheimer’s Disease,

NeuroAIDS,



Amyotrophic Lateral Sclerosis,

Human brain tumors

From 2009 I have been acting as expert of the European Medicine Agency,

Sciences Medicine Health. In 2009 he was invited as EMEA delegate to theCommittee for Human

Medicinal Products (CHMP) Scientific Advisory Group (SAG) for CNS, in London. The meeting was

held in order to discuss about the problem of the Progressive Multifocal Leukoencephalopathy

development in Tysabri-teatred Multiple Sclerosis patients. This question is still open andI amfocusing

most of my researches on the topic.

The following year,I was called as delegate to the CHMP SAG for CNS meeting in

London, focused on the use of Raptiva in patients affected with Psoriasis.

In addition all my scientific activity is carried out in an international contest, since I have many

collaborations with European and ExtraEu goups working on the same topics. In order to help

spreading the knowledge of the scientific community I belong to ,I was and I am still part of the scientific

committees of many international peer reviewed scientific symposiums. In addition, I was awarded by

the National Institute of Health (NIH) for my research activity from 2003 to 2010.

Publications 1.Profeta ML,Ferrante P: Prevalenza degli anticorpi verso virus influenzali A/NewJersey/76, A/Victoria/3/75 e B/Hong Kong/5/72 nella popolazione milaneseesaminata nella tarda primavera 1976 e valutazione dell'esperienza dellapopolazione in studio nei confronti del probabile agente della pandemia del1918-1920. Boll Ist Sieroter Milan, 55, 272-278, 1976

2.Profeta ML,Ferrante P, Kotseva R: Temperatura ottimale d'attività enzimatica etermoresistenza delle neuraminidasi come marcatori di attenuazione per i virusinfluenzali. Boll Ist Sieroter Milan, 56, 410-417, 1977

3.Profeta ML, DeVito D, Ferrante P: Incidenza degli anticorpi inibenti l'emoagglutinazionenelle popolazioni di Milano e Bari verso i ceppi di virus influenzalid'importanza epidemiologica per l'inverno 1977-1978. Boll Ist Sieroter Milan, 57,95-100, 1978

4.Profeta ML,Ferrante P: Indicazioni sull' età di applicazione della vaccinazioneantimorbillo in Lombardia come risulta da un'indagine sieroepidemiologicaeffettuata a Milano. Boll Ist Sieroter Milan, 57, 549-554, 1978

5.Ferrante P,Profeta ML, Fasan M: Il ruolo del laboratorio virologico nella diagnosidella PESS Osservazioni su 12 casi studiati tra il maggio 1977 ed il marzo1978. BollIst Sieroter Milan, 57, 575-582, 1978

6.Di Pietro C, Del Guercio MJ, Paolino GP, Barbi M,Ferrante P, Chiumello G: Type 1 diabetesand Coxsackie virus infection. Helv Ped Acta, 34,43-50, 1979



7.Bergamini F,Ferroni P, Ferrante P, Profeta ML, Zanetti A: Panencefalite SclerosanteSubacuta: epidemiologia e dati di laboratorio. Agg Mal Inf Immun, 25,43-50, 1979

8.Profeta ML,Bigatello A, Vacchini V, Bramati L, Ferrante P: Confronto tra vacciniantinfluenzali inattivati contenenti subunita' e preparazioni a virioni interi:studio della reattogenicita' e del potere immunizzante in bambini ed adulti.Boll IstSieroter Milan, 58, 457-474, 1979

9. Ferrante P, Fasan M, Barbi M: Indaginesieroepidemiologica sulla diffusione dell'infezione da Rotavirus nellapopolazione milanes.e Boll Ist Sieroter Milan, 59, 126-132, 1980

10.Ferrante P, Barbi M, Fasan M: Stato attualedell'immunita' verso la poliomelite della popolazione di Milano Risultatipreliminari. Igiene Moderna , 74, 917-925,1980

11.Ferrante P, Barbi M, D'Angelo A: Indaginivirologiche in 15 casi di sindrome di Guillain-Barré. Ann Microbiol, 30,39-41,1980

12.Bergamini F, Breschi F, Ferrante P, D' Angelo A: PanencefaliteSclerosante Subacuta (PESS) Osservazionicliniche ed epidemiologiche su 56 casi studiati dal 1956 al 1978. MinervaMedica, 72, 21-32, 1981

13.Caputo D, Ferrante P,Fasan M, Procaccia S: Measles antibodies in multiple sclerosis patients.Boll Ist Sieroter Milan , 60,57-60, 1981

14.Profeta ML, Ferrante P, Ballerini P, Rossetti A: Episodioepidemico di gastroenterite da rotavirus in una comunita' di anziani. Annali Sclavo, 23,467-476, 1981

15.ProfetaML, Ferrante P: Capacita' dei vaccini antinfluenzali contenenti subunitànell'indurre la formazione di anticorpi eterologhi. Boll Ist Sieroter Milan, 60,268-277, 1981

16.Ferrante P, Fasan M, Barbi M: Significato deglianticorpi antivirali nel liquor in malattie da virus lenti. Giorn Mal InfParass , 33, 1215-1219, 1981

17.FerranteP, Mendogni D: Evidenziazione dei Rotavirus nelle feci mediante la reazionedi fissazione del complemento. Boll Ist Sieroter Milan ,60, 375 – 380, 1981



18.Ferrante P, Caputo D, Fasan M, Barbesti S: Anticorpisierici e liquorali verso il virus del morbillo in pazienti affetti da sclerosimultipla. Arch Sc Med , 139, 39-43, 1982

19.Barbi Guidotti M, Cappellini D, Pedretti CC, FerranteP: Circolazione di Echovirus 23 inun reparto di patologia neonatal.e Annali Sclavo, 24, 76-84, 1982

20.Ferrante P, CaputoD, Barbesti S, Fasan M: Viral Antibodies in Multiple Sclerosi.s Ital JNeurol Sci, 2, 115-118, 1982

21.Bergamini F, Ferrante P: Osservazioniepidemiologiche sull' andamento della Panencefalite Sclerosante Subacuta (PESS)in Lombardia. Annali Sclavo, 24, 290-296; 1982

22.ML Profeta, P Ferrante: Virus del morbillo esclerosi multipla. Annali Sclavo, 24, 297-301; 1982

23.FerranteP, Cappellini D, Ferliga A, Ballerini P, Cauda Pedretti C, Lattanzio M: Leinfezioni da rotavirus in una unita' di patologia neonatale. Boll Ist Sieroter Milan, 62,37-46, 1983

24.D'Angelo A,Ferrante P, Barbi Guidotti M, Provera P: Influenza B-associated Reyesyndrome: report of a case with isolation of a coxsackie A5 virus from CSF.Ital J Neurol Sci, 3, 329-334,1983

25.Barbi M, Ferrante P, Achilli G: Valutazione deimetodi immunoenzimatici nella diagnosi sierologica dell'infezione dacytomegalovirus. Igiene Moderna, 80, 712-725, 1983

26.ProcacciaS, Borroni G, Lanzanova D, Papini E, Perego R, Ferrante P: IgGrheumatoid factors behaviour in youngnormal subjects following vaccination. Boll Ist Sieroter Milan 62,451-461, 1983

27.Maspero A, Sesana B, FerranteP: Adverse reactions to measles vaccine. Boll Ist Sieroter Milan, 63,125-129, 1984

28.Bianchi Porro G,Bergamini F, Sangaletti O, Ferrante P, Petrillo M: Herpes Simplex virus andduodenal ulcer. Ital J Gastroenterol,16, 135, 1984



29.Gerna G, Torsellini M, Passarani N, Battaglia M,Percivalle E, Sarasini A, Torre D, Ferrante P: Subgrouping of humanrotavirus strain by complement fixation, indirect double-antibody sandwichenzime-linked immunosorbent assay and solid-phase immune electron microscopy.Arch Virol, 81, 193-203,1984

30.FerranteP, Mantovani A: Considerazioni sul ruolo degli animali in alcune malattiedel sistema nervoso centrale dell'uomo. Ann Ist Sup San, 20,387-400, 1984

31.Lazzarin A, Galli M,Introna M, Negri C, Mantovani A, Mella L, Ferrante P, Parravicini C, TrombiniM, Aiuti F, Moroni M, Zanussi C: Outbreak of persistent, unexplained,generalized lymphoadenopathy with immunological abnormalities in drug addictsin Milan. Infection, 12,372-376,1984

32.Gerna G, Battaglia M, Passarani N, Percivalle E,Torsellini M, Ferrante P: Identificazione di sottogruppo dei ceppi dirotavirus umani. Giorn Mal Inf Parass, 37, 141- 143, 1985

33.Fontana M, Paccagnini S, Zuin G, Ballerini P, RuggeriM, Ferrante P: Rotavirus ed infezione respiratoria. Giorn Mal InfParass, 37, 1071-1077, 1985

34.BarbiM, Cappellini D, Ferrante P, Ruggeri M, Lattanzio M, Ferliga A, Rizzo M: Infezionicongenite da cytomegalovirus in una unita'di patologia neonatale. Boll Ist Sieroter Milan, 64,262-268, 1985

35.Zaffaroni M, Caputo D, Ghezzi A,Ferrante P, Cazzullo C L: T lymphocyte subpopulations in multiple sclerosis.Acta Neurologica, 7, 328-337, 1985

36.Ferrante P, Veraldi S, LacchiniR, Barbi M, Marini D : Virological findings in a case of Kaposi's sarcoma. ItalGen Rev Derm, 22, 63-67, 1985

37.Boiardi A, Ferrante P, Porta E,Sghirlanzoni A, Bussone G: Herpes Zooster myelitis: nervous systemcomplications. Ital J Neurol Sci, 7, 617-622, 1986

38.Profeta ML, Ferrante P, PorroDe' Somenzi C: A survey on factors affecting acceptance of measles vaccine. Eur J Epidemiol, 2,128-133, 1986

39.Ferrante P, Nardi G, Zanchetta N,



Salvioni PM, Pagano A: Prevalance of HTLV III-LAV and other viral antibodyin normal and risk population.s BollIst SieroterMil, 65, 357-360, 1986

40.Bergamini F, Castellani P, Ferrante P: Diagnosi dilaboratorio di conferma dell'infezione da HTLV III-LAV . L'Igiene Moderna, 86,537-546, 1986

41.Cianchetti C,Ferrante P, Marrosu MG: Subacute Sclerosing panencephalitis in ItalyAn epidemiological study. Acta NeurolScand, 73, 160-167, 1986

42.FontanaM, Zuin G, Paccagnini S, Ferrante P, Gandini G, Principi N: Osservazoniepidemiologiche su 337 casi di diarrea acuta in eta' infantile. Ann Ist Super Sanita', 22,839-842, 1986

43.Ferrante P, Achilli G,Gerna G, Bergamini F: Subacute SclerosingPanencephalitis: detection of measles antibody in serum and CSF byenzyme linked immunosorbent assay, complement fixation and hemagglutinationinhibition. Microbiologica, 10,111-118, 1987

44.Fontana M, Zuin G, Paccagnini S, Quaranta S, Villa M,Gandini G, Ferrante P: Osservazioni cliniche e microbiologiche in 157 casidi diarrea acuta infantile. Riv Inf Ped, 2,27-33, 1987

45.De Freitas H,Wroblewska Z, Maul G, Sheremata W, Ferrante P, Lavi E, Harper M, Di MarzoVeronese F, Koprowski H: HTLV I infection of cerebrospinal fluid T cellsfrom patients with cronic neurological disease. AIDS Res Hum Retrov, 3,19-37, 1987

46.Ferrante P,Castellani P, Barbi M, Bergamini F: The italian cooperative multiplesclerosis case-control study: preliminary results on viral antibodies. ItalJ Neurol Sci, S 6, 45-50, 1987

47.Caputo D, FerranteP, Zaffaroni M, Ghezzi A, Cazzullo CL: Longitudinal survey of T-lymphocytesand viral antibodies in MS patients. Ital J Neurol Sci, S 6, 53-56,1987

48.ProfetaML, Ferrante P, Mendogni D: Correlazioni tra riscontri sierologici e datianamnestici nell'ambito delle principali malattie virali dell'infanzia. Boll Ist Sieroter Milan, 66,367-376, 1987

49.MaielloA, Zotti C, Moiraghi Ruggenini A, Ferrante P, Castellani P, Goretto G: Infezioneda HIV: studio relativo ad una popolazione di studenti extraeuropei. Boll Ist Sieroter Milan, 66,440-



447, 1987

50.Ferrante P, Cisco M, Moise A, Defanti CA, WroblewskaZ: Analisi della risposta anticorpale verso le proteine dei virus VaricellaZoster in pazienti con disordini neurologici conseguenti a Varicella o HerpesZoster. Riv Neurobiologia, 33, 367- 375, 1987

51.Procaccia S, Lanzanova D, Caputo D, Ferrante P, PapiniE, Gasparini A, Colucci A, Bianchi M, Villa P, Blasio R, Froldi M, Zanussi C: Circulatingimmune complexes in serum and cerebrospinal fluid of patients with multiplesclerosis. Acta Neurol Scand, 77, 373-381, 1988

52.Veraldi S, Ferrante P, Barbi , Mancuso R, Brambilla L,Marini D: Anticorpi anti-cytomegalovirus e sarcoma di Kaposi. GiornaleItaliano di Dermatologia e Venereologia, 123, 75- 77, 1988

53.Ferrante P, Vaccari CE: Elevati livelli dei fattoriC3 e C4 in pazienti schizofrenici in associazione ad alterazioni cerebralievidenziate alla TAC. Notiziario Clinico Beckman, 2-3, 23-24, 1989

54.Ferrante P, Saresella M, Cocuzza CE, Caputo D,Cattaneo E, Achilli G, Cazzullo CL: HTLV 1 Antibodies in Multipe Sclerosisand Other Neurological Disease. Acta Neurologica, 11, 95-99, 1990

55.Ferrante P, Cocuzza CE, Mancuso R, Caputo D, SalvioniP, Cattaneo E, Achilli G, Cazzullo CL: HTLV I Antibodies in Italian Drug Addicts,Homosexual males Neurological patients and Healthy subjects. Int J ImmunopathPh, 35, 101-105, 1990

56.Zella D, Mori L, Sala M, Ferrante P, Casoli C, MagnaniG, Achilli G, Cattaneo E, Lori F, Bertazzoni U: HTLV-II infection in Italiandrug abusers. Lancet, 336, 575-576, 1990

57.Masserini C, Vita A, Basile R, Morselli R, Boato P,Peruzzi C, Pugnetti L, Ferrante P, Cazzullo CL: Lymphocyte subsets inschizophrenic disorders Relationship with clinical, neuromorphological andtreatment variables. Schizophr Res, 3, 269-275, 1990

58.Cattaneo E, Zella D, Cimarelli A, Mori L, Achilli G,Landini V , Maccabruni A, Caselli D, De Cas A, Casoli C, Ferrante P, BertazzoniU: Concordance of HIV in colture and PCR analysis in the diagnosis ofvertically transmitted infection. Pediatric AIDS, 3,183-186, 1992

59.Ferrante P, Galli A, Mendozzi E, Maffezzoli I,Ottogalli G: Ricerca ed evidenziazione di Rotavirus in alimenti. AnnMicrobiol Enzimol, 42, 275 –280, 1992



60.FerranteP, Caputo D, Mori L, Zella D, Achilli G, Bertazzoni U, Cazzullo CL: Detectionof HTLV-I DNA sequences in Multiple Sclerosis patients. J Trop Geograph Neurol, 2,97-101, 1992

61.Goj P, Caputo D, Bairati C,Lombardo A, Burlina AB, Ferrante P, Cazzullo CL, Tettamanti G: Enzymes oflysosomal origin in the cerebrospinal fluid and plasma of patients withMultiple Sclerosis. Eur Neurol, 33, 1-4, 1993

62.Caldarelli R, Li L,Omodeo Zorini E, Vago L, Boldorini R, Ferrante P: Detection of JC virus in brain tissue and cerebrospinalfluid from patients with AIDS by PCR-DEIA. Minerva Biotec, 5, 178-180, 1993

63.Ferrante P, Magistrelli C: Biologia dell'antisenso.Diagnosis, 3, 101-103, 1993

64.Saresella M, Mendozzi E, De Benedittis R, Bucci L,Ferrante P: Applicazioni della citometria a flusso per lo studio della fagocitosi e del killing.Diagnosis, 3, 137-140, 1993

65.Westarp MG, Ferrante P, Perron H, Schraff S, WestarpMP, Kornhuber HH: Antiretroviral seroreactivity in sporadic adultamyotrophic lateral sclerosis. Neur Psych Brain Res, 3, 1-6, 1994

66.Gabutti G, Butini M, Gazzola P, Faraldi L, Ferrante P,Lazzareschi M, Piersantelli N, Rizzo F, Wicks R, Crovari P: HTLV-I andHTLV-II epidemiology in Liguria. J Prev Med Hygiene, 35,155-160,1994

67.Pacelli L, BerettaA, Bionda A, Scagnol I, Speciale L, Brucato F, Palmieri G, Ferrante P: Modulationof cytokines release from human endothelial cells by Coumarine. J ExperClin Canc Res, 14, 1S, 124-125; 1995

68.Maffezzoli I, GalliA, Caldarelli R, Omodeo Zorini E, Ferrante P: Detection of Salmonellaspp in food by polymerase chain reaction. Ann Microbiol Enzimol, 45, 165-172; 1995

69.Ferrante P, Westarp ME,Mancuso R, Puricelli S, Caputo D, Zuffolato MR: Presence of HTLV DNA andantibodies in sporadic amyotrophic lateral sclerosis. Neurol Psyc Brain Res, 3,11-16; 1995

70.Ferrante P, Westarp ME, Mancuso R,Puricelli S, Westarp MP, Mini M, Caputo D, Zuffolato MR: HTLV tax-rex DNAand antibodies in idiopathic amyotrophic lateral sclerosis. J Neurol Sci, 129S,140-144, 1995



71.Westarp ME, Ferrante P, PerronH, Bartmann P, Kornhuber HH: Sporadic ALS/MND: a global neurodegenerationwith retroviral involvment ? J Neurol Sci, 129S, 145-147, 1995

72.Colombo E, Magistrelli C,Mendozzi E, Cattaneo E, Achilli G, Ferrante P: HTLV infection among italianintravenous drug users and north african subjects detected by the polymerasechain reaction and serological methods. J Med Virol, 47, 10-15, 1995

73.Saresella M, Grope A, SpecialeL, Mancuso R, De Benedictis R, Caputo D, Ferrante P: Evidence for a missedsignal to the CD8+ cells in CSF of Multiple Sclerosis Patients. It J NeurolSci, 7, 479-485, 1995

74.Aversa E, Grope A, Mancuso R, Saresella M, Caputo D,Maserati R, Ferrante P: Correlazione tra un nuovo metodo adimmunofluorescenza e la citometria a flusso per la misurazione dei livelliassoluti dei linfociti-T CD4+ e CD8+ . Med Lab, 3, 137-139, 1995

75.FerranteP, Caldarelli-Stefano R, Omodeo-Zorini E, Vago L, Boldorini R, Costanzi G: PCRdetection of JC virus DNA in brain tissue from patients with and withoutprogressive multifocal leukoencephalopathy. J Med Virol, 47,219-225, 1995

76.Maffezzoli I, Galli A,Caldarelli R, Omodeo-Zorini R, Ferrante P: Detection of Salmonella spp bynested polymerase chain reaction. Microecology and Therapy, 25,388-392; 1995

77.Garagiola U, Buzzetti M,Cardella M, Confalonieri F, Giani E, Polini V, Ferrante P, Mancuso R, MontanariM, Grossi E, Pecori A: Immunological patterns during intensive training inathletes: quantification and evaluation of a preventive pharmacologicalapproach. J Int Med Res, 23, 85-95,1995

78.Vago L, Cinque P, Sala E,Nebuloni E, Caldarelli R, Racca S, Ferrante P, Trabattoni GR, Costanzi G: JCVDNA and BKV DNA in the CNS and cerebrospinal fluid of AIDS patients and normalsubjects Study on 43 cases and review of the literature. J AIDS, 12,139-146, 1996

79.Taramelli D, Sala G, MalabarbaMG, Malacarne F, Saresella M, Ferrante P, Frigerio S, Lombardi L: Aspergillusfumigatus conidia adhere and activate human endothelial cells. Micol Lek (Medical Mycology), 3, 75-81 1996

80.Wen H, Caldarelli-Stefano R,Tortorano AM, Ferrante P, Viviani MA: A simplified method to extracthigh-quality DNA from Cryptococcus neoformans. J Mycol Mèd, 6,136-138, 1996



81.Vallejo A, Ferrante P, SorianoV, Calabrò ML, Mancuso R, Heredia A, Mannella E, Favero A, Garcia-Sàinz A,Chieco-Bianchi L, Gonzàles-Lahoz J, Hewlett IK: Nucleotide sequence andrestriction fragment-lenght polymorphism analysis of Human T-cell LymphotropicVirus Type II (HTLV-II) in Southern Europe: evidence for the HTLV-IIa andHTLV-IIb subtypes. J AIDS Hum Retrovir,13, 384-391, 1996

82.Ferrante P, Caldarelli-StefanoR, Omodeo-Zorini E, Cagni AE, Cocchi L, Suter F, Maserati R: Comprehensiveinvestigation of JC virus presence in AIDS patients with and withoutprogressive multifocal leukoencephalopathy: PCR, neuroradiological andlaboratory findings. J Med Virol, 52, 235-242, 1997

83.Ferrante P, Mancuso R,Zuffolato R, Puricelli S, Mannella E, Romanò L, Zanetti AR,Cattaneo E, Corrao V: Molecular analysis of HTLV-I and HTLV-II isolates fromitalian blood donors, intravenous drug users and prisoners. Microbiologica,20, 93-104,1997

84.Cristallo A, Gambaro F,Biamonti G, Ferrante P, Battaglia M, Cereda PM: Human coronaviruspolyadenilated RNA sequences in cerebrospinal fluids from multiple sclerosispatients. Microbiologica, 20, 105-114,1997

85.Ferrante P, Omodeo-Zorini E,Zuffolato MR, Mancuso R, Caldarelli-Stefano R, Puricelli S, Mediati M, LoscialeL, Caputo D: HTLV tax and EBV DNA in peripheral blood of multiple sclerosispatients during acute attack. Acta Neurol Scand, 95, s79-85, 1997

86.Colombo E, Banki K, Tatum AH,Daucher J, Ferrante P, Murray RS, Phillips PE, Perl A: Comparative analysisof antibody and cell-mediated autoimmunity to transaldolase and myelin basicprotein in patients with multiple sclerosis. J Clin Invest,99,1238-1250, 1997

87.Calabresi L, Franceschini G,Sirtori CR, De Palma A, Saresella M, Ferrante P, Taramelli D: Inhibition ofVCAM-1 expression in endothelial cells by reconstituted high densitylipoproteins. Bioch Biophys Res Comm, 238, 61-65, 1997

88.Viviani MA, Wen H, RoverselliA, Caldarelli-Stefano R, Cogliati M, Ferrante P, Tortorano AM: Identificationby polymerase chain reaction fingerprinting of Cryptococcus neoformans serotypeAD J Med Vet Mycol, 35, 355-360,1997

89.Saresella M, Roda K, SpecialeL, Taramelli D, Mendozzi E, Guerini FR, Ferrante P: A rapid evaluation ofphagocytosis and kolling of Candida albicans by CD13+ leukocytes. J ImmunolMethods,210, 227-234, 1997



90.Graziani MS, Ceriotti F, Carobene A, Modenese A,Ferrero C, De Giorgi E, Franzin M, Marchetti C, Brambilla P, Bertona M,Giannone D, Righetti G, Marocchi A, Prencipe L, Franzini C, Luraschi P,Mocarelli P, Bordone F, Mattathil S, Mariniello B, Savarino A, Panzini N,Fuscio A ,Siclari V, Pedicini G, Robba L, Bandello P, Vinci E, Malacrida V,Carluccio AV, Carmignoto F, De Ambrogio P, Romano R, Spagnoletti G, CondorelliM, Gulletta E, Guarguaglini M, Bianchi-Bosisio A, Airo R, Di Sciascio N, NeriG, Antinozzi R, Panciroli G, Perazzi C, De Leo G, Berti P, Biddau A, MarchettiL, Bossini S, Martinelli M, Baldini G, Aureli G, Golato M, Venturini M, TroinaE, Mancosu M, Cicatelli P, Ottomano C, Ferrante P, Berlusconi A, Bianco L,Carati JL, Bolletti-Censi M, De Capua R, Aquili C, Scola B, Manzo F, BorsellinoF, Nubile G, Romagnoli M, Ridolfi A, Bartolucci M, Apicella P, Pace R, CasertanoP, Callegaris F, Innocenti B, Mammini P, Cappelletti P, Pendino G, Cavalleri M,Volpones GB, Recchia O, Benedetti R, Casparrini G, Macchiolo M, Bazzanti VestriV, Bianchini A, Barbieri-Palmieri F, Craca S, Tiraboschi L, Guerrini L, PagniR, Capra E, Vultaggio C, Paltrinieri E, Di Carlo E, Colombo M, Lo Monaco G, etal.: Accuracy of cholesterol measurements in Italian clinical laboratoriesJoint Project GISSI Prevention - Italian Society of Clinical Biochemistry. EurJ Clin Chem Clin Bioch, 35, 311-315, 1997

91.Perron H, Garson JA, Bedin F, Beseme F,Paranhos-Baccala G, Komurian- Pradel F, Mallet F Tuke PW, Voisset C, Blond JL,Lalande B, Seigneurin JM, Mandrand B, Hauw JJ, Escourolle R, Schuller E, PellatJ, Perret J, Mallaret M, Ferrante P: Molecular identification of a novelretrovirus repeatedly isolated from patients with multiple sclerosis. ProcNat Acad Sci USA, 94, 7583-7588, 1997

92.TaramelliD, Basilico N, De Palma AM, Saresella M, Ferrante P, Mussoni L, Olliaro P: Theeffect of synthetic malaria pigment (b-haematin) on adhesion molecule expression andinterleukin-6 production by human endothelial cells. T Roy Soc Trop Med H, 92, 57-62, 1998

93.Saresella M, Roda K, Speciale L,Taramelli D, Mendozzi E, Guerini FR, Ferrante P: A flow cytometric methodfor the analysis of phagocytosis and killing by polymorphonuclear leukocytes.Ann NYAcad Sci, 832, 53-61, 1998

94.Speciale L, Roda K, SaresellaM, Taramelli D, Ferrante P: Different endothelins stimulate cytokineproduction by peritoneal macrophages and microglial cell line. Immunology, 93,109-114, 1998

95.Ferrante P, Fusi ML, Saresella M, Caputo D, Biasin M,Trabattoni D, Salvaggio A, Clerici E, de Vries JE, Aversa G, Cazzullo CL,Clerici M: Cytokine production and surface marker expression in acute and stablemultiple sclerosis: altered IL-12 production and augmented signalinglymphocytic activation molecule (SLAM)-expressing lymphocytes in acute multiplesclerosis. J Immunol, 160, 1514-1521, 1998

96.Boldorini R,Caldarelli-Stefano R, Monga G, Zocchi M, Mediati M, Tosoni A, Ferrante P:PCR detection of JC virus DNA in the brain tissue of a 9-year-old child with



pleomorphic xantoastrocytoma. JNeuroVirol, 4, 242-245, 1998

97.Ferrante P, Omodeo Zorini E, Caldarelli-Stefano R,Mediati M, Fainardi E, Granieri E, Caputo D: Detection of JC virus DNA incerebrospinal fluid from multiple sclerosis patients. Multiple Sclerosis, 4,49-54, 1998

98.CazzulloCL, Saresella M, Roda K, Calvo MG, Bertrando P, Doria S, Clerici M, SalvaggioA, Ferrante P: Increased levels ofCD8+ and CD4+45RA+ lymphocytes in schizophrenic patients. ShizophreniaResearch, 31, 49-55, 1998

99.Gotti E, Abbate M,Ferrante P, Remuzzi G : Abdominal pain and acute nephritis in a man with arecent renal transplant. J Nephrology, 11,196-198, 1998

100.Rizzardini G, Trabattoni D, Saresella M, Piconi S, Lukwiya M, DeclichS, Fabiani M, Ferrante P, Clerici M: Immuneactivation in HIV-infected African individuals. AIDS, 12, 2387-2396,1998

101.Viganò A, Saresella M, RusconiS, Ferrante P, Clerici M: Expression of CD38 on CD8 T cells predictsmanteinance of high viraemia in HAART-treated HIV-1-infected children.Lancet, 352, 1905-1906,1998

102.Torre D, Speranza F, MarteganiR, Ferrante P, Omodeo-Zorini E, Mancuso R, Fiori GP: Meningoencephalitiscaused by human herpesvirus-6 inan immunocompetent adult patient: case report and review of the literature.Infection, 26, 402-404, 1998

103.Caldarelli-Stefano R, Vago L,Omodeo-Zorini E, Mediati M, Losciale L, Nebuloni M, Costanzi G,Ferrante P: Detection and typing of JC virus in autopsy brains andextraneural organs of AIDS patients and non-immunocompromised individuals. J NeuroVirol, 5, 125-133, 1999

104.Veraldi S, Mancuso R,Rizzitelli G, Gianotti R, Ferrante P: Henoch-Schonlein syndrome associatedwith human Parvovirus B19 primary infection. European Journal ofDermatology, 9, 232-233, 1999

105.Veraldi S, Ferrante P, MancusoR, Gianotti R, Caputo R: Evidence of retroviral involvement in an Italianpatient with Ofuji's diseas.e Dermatology, 198, 86-89, 1999

106.Magistrelli C Samoilova E



Agarwal RK Banki K Ferrante P, Vladutiu A Phillips PE Perl A: Polymorphicgenotypes of the HRES-1 human endogenous retrovirus locus correlate withsystemic lupus erythematosus and autoreactivity. Immunogenetics, 49,829-834, 1999

107.Clerici M, Fusi ML, Caputo D,Guerini FR, Trabattoni D, Salvaggio A, Cazzullo CL, Arienti D, Villa ML,Urnovitz HB, Ferrante P: Immune Response to antigens of human endogenousretroviruses in patients with acute or stable multiple sclerosis. JNeuroimmunol, 99,173-182, 1999

108.Jolivet-Reynaud C, Perron H,Ferrante P, Becquart L, Dalbon P, Mandrand B: Specificities of multiplesclerosis cerebrospinal fluyid and serum antibodies against mimotopes. ClinImmunol, 93, 283-293, 1999

109.Viganò A, Vella S, SaresellaM, Vanzulli A, Bricalli D, Di Fabio S, Ferrante P, Andreotti M, Pirillo M,Dally LG, Clerici M, Principi N: Early immune reconstitution after potentantiretroviral therapy in HIV-infected children correlates with the increase inthymus volume. AIDS, 14, 251-261, 2000

110.Caldarelli-Stefano R,Boldorini R, Monga G, Meraviglia E Zorini-Omodeo E, Ferrante P: JC virus inhuman glial-derved tumors. Human Pathology, 31, 394-395, 2000

111.Ferrante P: The puzzlingnatural history of multiple sclerosis: a challenge for the research and care.J Neurovirol, 6, S2, 1-3, 2000

112.Guerini FR, Losciale L,Mediati M, Speciale L, Mancuso R, Saresella M, Calvo MG, Caputo D, Ferrante P: Apolymorphism in the repetitive (TGGA)n sequence 5’to the human myelin basic protein gene in Italian multiple sclerosis patients.J Neurovirol, 6, S2, 28-32, 2000

113.Trabattoni D, Ferrante P, FusiML, Saresella M, Caputo D, Urnovitz H, Cazzullo CL, Clerici M: Augmentedtype 1 cytokines and human endogenous retroviruses specific immune response inpatients with acute multiple sclerosi.s J Neurovirol, 6, S2,38-41, 2000

114.Pintèr C, Beltrami S, CaputoD, Ferrante P, Clivio A: Presence of autoantibodies against complementregulatory proteins in relapsing-remitting. J Neurovirol, 6, S2,42-46, 2000

115.Speciale L, Saresella M,Caputo D, Ruzzante S, Mancuso R, Calvo MG, Guerini FR, Ferrante P: Serumauto antibodies presence in multiple sclerosis patients treated with b-interferon 1a and1b.J Neurovirol, 6, S2, 57-61, 2000



116.Speciale L, Saresella M,Ruzzante S, Caputo D, Mancuso R, Calvo MG, Guerini FR, Ferrante P: Endothelinand nitric oxide levels in cerebrospinal fluid of patients with multiplesclerosis. J Neurovirol, 6, S2, 62-66, 2000

117.Ferrante P, Mancuso M, Pagani E, Guerini FR, Calvo MG, Saresella M,Speciale L, Caputo D: Molecular evidences for a role of HSV-1 in multiple sclerosisclinical acute attack. J Neurovirol, 6, S2, 109-114, 2000

118.Viganò A, Saresella M, VillaML, Ferrante P, Clerici M: CD38+CD8+ T cells as a marker of poor response to therapy in HIV-infectedindividuals. Chem Immunol, 75, 207-217, 2000

119.Beretta A, Clerici M, HassonH, Fumagalli L, Trabattoni D, Lillo F, Ferrante P, Saniabadi AR,Adachi M, Lazzarin A: Ex-vivo purging of circulating monocytes results inimmunovirologic improvement in partially HAART responder HIV-infected patients.J Biol Regul Homeost Agents, 14, 27-31, 2000

120.Clerici M, Buttò S, Lukwiya M,Saresella M, Declich S, Trabattoni D, Pastori C, Piconi S, Fracasso C, FabianiM, Ferrante P, Rizzardini G, Lopalco L: Immune activation in Africais environmentally-driven and is associated with upregulation of CCR5. AIDS,14, 2083-2092, 2000

121.Biasin M, Lo Caputo S,Speciale L, Colombo F, Racioppi L, Zagliani A, Blè C, Vichi F, Cianferoni L,Masci A M, Villa ML, Ferrante P, Mazzotta F, Clerici M: Mucosal and systemicimmune activation is present in human immunodeficiency virus-exposedseronegative women. JID 182 (5) 1365-1374, 2000

122.Clerici M, Saresella M,Colombo F, Fossati S, Sala N, Bricalli D, Villa ML, Ferrante P, Dally L, ViganòA: T lymphocyte maturation abnormalities in uninfected new borns andchildren with vertical exposure to HIV. Blood, 96, 3666-3871, 2000

123.Ferrante P, Mediati M,Caldarelli-Stefano R, Losciale L, Mancuso R, Cagni A E, Maserati R: Increasedfrequency of JC virus type 2 and of dual infection with JC virus type 1 and 2 in Italian progressivemultifocal leukoencephalopathy patients.J Neurovirol, 7, 35-42, 2001

124.Ferrante P, Pagani E, MancusoR, Borghi E, Tarantini L, Mediati M, Fagà G, Delbue S, Maserati R, Cagni AESuter F : JCV Genotypes and Transcriptional Control Region Rearrangements ASRisk Factors for PML Development.[Article] 6th EuropeanConference on Experimental AIDS Research(ECEAR 2001) Heriot-Watt University,Edinburgh-Scotland 23rd –26th June 2001



125.Biasin M, Lukwiya M,Rizzardini G, Ceroni S, Maffeis G, Saresella M, Declich S, Fossati S, Trabattoni D, Clerici M: Single-CellAnalysis of Citokine Production in HIV-Infected and Unifected Individuals fromGulu, Uganda. 6th EuropeanConference on Experimental AIDSResearch (ECEAR 2001.) Heriot-Watt University,Edinburgh-Scotland 23rd –26th June 2001

126.Lukwiya M, Rizzardini G,Trabattoni D, Piconi S, Saresella M, Declich S, Fossati S, Clerici M Evaluationof Immune Activation in HIV-Infecyed and Unifected African Individuals bySingle-Cell Analysis of Cytokine Production. J Acquir Immune Defic Syndr, 28(5):429-436,2001

127.Clerici M, Saresella M,Trabattoni D, Speciale L, Fossati S, Ruzzante S, Cavarretta R, Filippi M, Caputo D, Ferrante P Single-cellanalysis of cytokine production shows different immune prifiles in multiplesclerosis patients with active or quiescent disease. J Neuroimmunol, 121: 88-101, 2001

128.Fusco C, Andreone V,Coppola G, Luongo F, Guerini F, Pace E, Florio C, Pirozzi G, Lanzillo R, Ferrante P, Vivo P, Mini M, Macrì M,Orefice G, Lombardi ML HLA-DRB1*1501 and response to copolymer-1 therapy inrelapsing remitting multiple sclerosis. Neurology,57: 1976-1979, 2001

129.Granieri E, Casetta I, Tola MR, Ferrante P Multiplesclerosis: infectious hypotesis. Neurol Sci: 22, 179-185, 2001

130.Lazzarin A, Clerici M, Hasson H, Fumagalli L, Ferrante P, Saniabadi AR,Adachi M, Beretta A Immunovirological improvement in partially HAARTresponder HIV-infected patients by monocyte adsorption apheresis. J Clin Apheresis.2001; 16(1): 35-6.

131.Del Valle L, Delbue S, GordonJ, Enham S, Croul S, Ferrante P, Khalili K Espression of JC Virus T-antigenin patient with MS and glioblastoma multiforme. Neurology, 58:895-900, 2002

132.Hasson H, Saniabadi A, AlfanoM, Trabattoni D, Ferrante P, Lillo F, Clerici M, Lazzarin A, Beretta A Granulocyte/monocyte apheresis inducessustained increases in CD4 T cells in HIV-1 infected patients with poor CD4 Tcell restoration after suppression of viral replication by HAART . J BiolRegul Homeost Agents 16: 58-63, 2002

133.Clerici M, Saresella M,Trabattoni D, Ferrante P, Vanzulli A, Viganò A Thymic volume predictslong-term immune reconstitution in HIV-infected children treated with highlyactive antiretroviral therapy. AIDS 16: 2219-21, 2002



134.Basilico N, Speciale L,Parapini S, Ferrante P, Taramelli D Endothelin-1 production by amicrovascular endothelial cell line treated with Plasmodium falciparumparasitized red blood cells. Clin Sci (Lond) 48:464S-466S, 2002

135.Beretta A, Hasson H, SamiabadiA, Alfano M, Trabattoni D, Lillo F, Ferrante P, Clerici M, Lazzarin A Selective granulocyte/monocyte apheresisin the treatment of HIV-infected patients: short-term and long-term effects onimmunological and virological parameters. Perfusion 17 Suppl: 47-51,2002

136.Trabattoni D, Saresella M,Biasin M, Boasso A, Piacentini L, Ferrante P, Dong H, Maserati R, Shearer GM,Chen L, Clerici M B7-H1 is up-regulated in HIV infection and is a novelsurrogate marker of disease progression. Blood 101: 2514-20, 2003

137.Ferrante P, Saresella M,Guerini FR, Marzorati M, Musetti MC, Cazzullo AG Significant association ofHLA A2-DR11 with CD4 naive decrease in autistic children. BiomedPharmacother 57: 372-374, 2003

138.Havlir DV, Strain MC, ClericiM, Ignacio C, Trabattoni D, Ferrante P, Wong JK Productive infection maintains a dynamicsteady state of residual viremia in human immunodeficiency virus type1-infected persons treated with suppressive antiretroviral therapy for fiveyears. J Virol 77: 11212-11219, 2003

139.Boldorini R, Pagani E, Car PG,Omodeo-Zorini E, Borghi E, Tarantini L, Bellotti C, Ferrante P, Monga G Molecular characterisation of JC virusstrains detected in human brain tumours. Pathology 35: 248-253, 2003

140.Pagani E, Delbue S,Mancuso R, Borghi E, Tarantini L, Ferrante P Molecular analysis of JC virusgenotypes circulating among the Italian healthy population. J Neurovirol 9: 559-566, 2003

141.Guerini FR, Ferrante P, Losciale L, Caputo D, Lombardi ML, Pirozzi G,Luongo V, Sudomoina MA, Andreewski TV, Alekseenkov AD, Boiko AN, Gusev EI,Favorova OO. Myelin basic protein gene is associated with MS in DR4- and DR5-positiveItalians and Russians.Neurology 61: 520-526, 2003

142.Speciale L, Ruzzante S,Calabrese E, Saresella M, Taramelli D, Mariani C, Bava L, Longhi R, Ferrante P 1-40Beta-amyloid protein fragment modulates the expression of CD44 and CD71 on theastrocytoma cell line in the presence of IL1beta and TNFalpha. J CellPhysiol 196:190-195, 2003



143.Ferrante P, Delbue S, PaganiE, Mancuso R, Marzocchetti A, Borghi E, Maserati R, Bestetti A, Cinque P Analysisof JC virus genotype distribution and transcriptional control regionrearrangements in human immunodeficiency virus-positive progressive multifocalleukoencephalopathy patients with and without highly active antiretroviraltreatment. J Neurovirol 9: 42-46, 2003

144.Kim J, Woolridge S, Biffi R,Borghi E, Lassak A, Ferrante P, Amini S, Khalili K, Safak M Members of theAP-1 family, c-Jun and c-Fos, functionally interact with JC virus earlyregulatory protein large T antigen. J Virol 77: 5241-5252, 2003

145.Liguori M, Sawcer S, SetakisE, Compston A, Giordano M, D'Alfonso S, Mellai M, Malferrari G, Trojano M,Livrea P, De Robertis F, Massacesi L, Repice A, Ballerini C, Biagioli T,Bomprezzi R, Cannoni S, Ristori G, Salvetti M, Grimaldi LM, Biunno I, Comi G,Leone M, Ferro I, Naldi P, Milanese C, Gellera C, Loredana LM, Savettieri G,Salemi G, Aridon P, Caputo D, Rosa Guerini F, Ferrante P, Momigliano-RichiardiP A whole genome screen for linkage disequilibrium in multiple sclerosisperformed in a continental Italian population. J Neuroimmunol 143:97-100, 2003

146.Andreewski TV, Guerini FR,Sudomoina MA, Boiko AN, Alekseenkov AD, Kulakova OG, Losiale L, Ferrante P,Gusev EI, Favorova OO DNA lenght polymorphism of tetranucleotide repeat atthe 5’side of the myelin basic protein gene in Russian Multiple Sclerosis Patients. MolBiol (Mosk). 2003 Nov-Dec; 37(6): 849-855. Russian.

147.Saresella M, Marini M, GueriniF, Ferrante P, Bella SD,Chiaramonte S, Riva A Peripheral blood dendritic cells increase inkidney-transpalnt patients without rejection. Clin. Immunol. 2004 Feb; 110(2):191-3

148.Gironi M, Lamperti C, Nemni R,Moggio M, Comi G, Guerini FR, Ferrante P, Canal N, Naini A, Bresolin N, DiMauro S. Late-onset cerebellar ataxia with hypogonadism and muscle coenzymeQ10 deficiency. Neurology 2004 Mar9; 62(5): 818-820.

149.Trabattoni D, Caputo SL,Maffeis G, Vichi F, Biasin M, Pierotti P, Fasano F, Saresella M, Franchini M,Ferrante P, Mazzotta F, Clerici M. Human alpha Defensin in HIV-Exposed ButUninfected Individuals. J Acquir Immune Defic Syndr. 2004 Mar 15; 35(5):455-463.

150.Basilico N, Mondani M, Parapini S, Speciale L, Ferrante P, TaramelliD. Plasmodium falciparum parasitized red blood cells modulate the productionof endothelin-1 by human endothelial cells. Minerva Med. 2004 Apr; 95(2):153-8.

150.Ballerini C, Guerini FR, Rombola G, Rosati E, Massacesi L, Ferrante P,Caputo D, Talamanca LF, Naldi P, Liguori M, Alizadeh M, Momigliano-Richiardi P,D’Alfonso S. HLA-multiple sclerosis association in Continental Italy and



correlation with disease prevalence in Europe. J Neuroimmunol. 2004 May; 150(1-2):178-85.

151.Gori A, Trabattoni D, BanderaA, Saresella M, Marchetti G, Gazzola L, Biasin M, Rhodes J, McDade H,Panebianco R, Galli M, Moroni M, Ferrante P, Thomas N, Franzetti F, Bray D,Clerici M. Immunomodulation induced by tucaresol in HIV infection: resultsof a 12 week pilot Phase I/II trial. Antiviral Therapy 2004 Aug, 9(4):603-614.

152.Viganò A, Saresella M, Trabattoni D, Giacomet V, Di Natale B, MerloM, Venuto A, Villa ML, Vanzulli S, Ferrante P, Clerici M. Growthhormone in T-lymphocyte thymicand postthymic development: A study in HIV-infected children . J Pediatr. 2004Oct;145(4):542-8.

153.BorghiE, Pagani E, Mancuso R, Delbue S, Valli M, Mazziotti R, Giordano L, Micheli R,Ferrante P. Detection of herpesvirus-6A in a case of subacute cerebellitisand myoclonic dystonia. J Med Virol. 2005; 75: 427-429

154.DelbueS, Sotgiu G, Fumagalli D, Valli M, Borghi E, Mancuso R, Marchioni E, MaseratiR, Ferrante P. A case of a PML patient with four different JC virus TCRrearrangements in CSF, blood, serum and urine. J Neurovirol. 2005; 1:51-58

155.FerranteP, Delbue S, Mancuso R. The manifestation of AIDS in Africa:an epidemiological overview. J Neurovirol. 2005; 11(S1): 50-57

156.GarsonJ, Creange J, Dolei A, Ferrante P, Jouvin-Marche E, Marche PN, Rieger F,Ruprecht K, Saresella M, Sotgiu S, Tedder R, Perron H, -. MSRV, Syncytin andthe role of endogenous retroviral proteins in demyelination. MultipleSclerosis. 2005; 11: 249-250

157.RollandA, Jouvin-Marche E, Saresella M, Ferrante P, Cavarretta R, Creange A, Marche P,Perron H. Correlation between disease severity and in vitro cytokineproduction mediated by MSRV (Multiple Sclerosis associated RetroViral element)envelope protein in patients with multiple sclerosis. J Neuroimmunol. 2005;160(1-2): 195-203

158.Delbue S, Sotgiu G, Fumagalli D, Valli M, Borghi E, Mancuso R, Marchioni E,Maserati R, Ferrante P. A case of a progressive multifocalleukoencephalopathy patient with four different JC virus transcriptionalcontrol region rearrangements in cerebrospinal fluid, blood, serum, and urine.J Neurovirol. 2005;11(1):51-7.



159.Oreja-Guevara C, Rovaris M, Iannucci G, Valsasina P, Caputo D, Cavarretta R,Sormani MP, Ferrante P, Comi G, Filippi M. Progressive gray matter damage inpatients with relapsing-remitting multiple sclerosis: a longitudinal diffusiontensor magnetic resonance imaging study. Arch Neurol. 2005;62(4):578-84.

160.Ferrante P, Delbue S, Mancuso R. The manifestation of AIDS in Africa:an epidemiological overview. J Neurovirol. 2005;11 Suppl 1:50-7.

161.Torre D, Mancuso R, Ferrante P. Pathogenic mechanisms ofmeningitis/encephalitis caused by human herpesvirus-6 in immunocompetent adultpatients. Clin Infect Dis. 2005;41(3):422-3.

162.Saresella M, Marventano I, Speciale L, Ruzzante S, Trabattoni D, Della Bella S,Filippi M, Fasano F, Cavarretta R, Caputo D, Clerici M, Ferrante P. Programmedcell death of myelin basic protein-specific T lymphocytes is reduced inpatients with acute multiple sclerosis. J Neuroimmunol. 2005;166(1-2):173-9.

163.Delbue S, Pagani E, Guerini FR, Agliardi C, Mancuso R, Borghi E, Rossi F,Boldorini R, Veggiani C, Car PG, Ferrante P. Distribution, characterizationand significance of polyomavirus genomic sequences in tumors of the brain andits covering. J Med Virol. 2005;77(3):447-54.

164.Guerini FR, Agliardi C, Zanzottera M, Delbue S, Pagani E, Tinelli C, BoldoriniR, Car PG, Veggiani C, Ferrante P. Human leukocyte antigen distributionanalysis in North Italian brain Glioma patients: an association withHLA-DRB1*14. J Neurooncol. 2006;77(2):213-7.

165.Rossi A, Mukerjee R, Ferrante P, Khalili K, Amini S, Sawaya BE. Humanimmunodeficiency virus type 1 Tat prevents dephosphorylation of Sp1 by TCF-4 in astrocytes. J GenVirol. 2006;87:1613-23.

166.Speciale L, Biffi R, Mancuso R, Borghi E, Mazziotti R, Ferrante P. Bigendothelin-1 and interleukin-6modulation in human microvascular endothelial cells after human herpesvirus 8infection. Exp Biol Med (Maywood).2006; 231(6):1171-5.

167.Guerini FR, Manca S, Sotgiu S, Tremolada S, Zanzottera M, Agliardi C, ZanettaL, Saresella M, Mancuso R, De SilvestriA, Fois ML, Arru G, Ferrante P. A Family



Based Linkage Analysis of HLA and 5-HTTLPR Gene Polymorphisms in SardinianChildren with Autism Spectrum Disorder. HumImmunol. 2006;67(1-2):108-17.

168. Speciale L, Calabrese E, SaresellaM, Tinelli C, Mariani C, Sanvito L, Longhi R, Ferrante P.

Lymphocyte subsetpatterns and cytokine production in Alzheimer's disease patients. Neurobiol Aging. 2007 Aug;28(8):1163-9.

169. Charil A, Caputo D, Cavarretta R,Sormani MP, Ferrante P, Filippi M. Cervical cord magnetization transfer ratio andclinical changes over 18 months in patients with relapsing-remitting multiplesclerosis: a preliminary study. Mult Scler. 2006, 12: 662-5.

170.Mancuso R, Delbue S, Borghi E, Pagani E, Calvo MG, Caputo D, Granieri E,Ferrante P.

Increased prevalence of varicella zostervirus DNA in cerebrospinal fluid from patients with multiple sclerosis. J Med Virol. 2007, 79: 192-9.

171. Rossi A, Delbue S, Mazziotti R,Valli M, Borghi E, Mancuso R, Calvo MG, Ferrante P.

Presence,quantitation and characterization of JC virus in the urine of Italianimmunocompetent subjects. J Med Virol. 2007, 79(4):408-12.

172.Khalili K, White MK, LublinF, Ferrante P, Berger JR. Reactivation of JC virus and development ofPML in patients with multiple sclerosis. Neurology. 2007 Mar 27;68(13):985-90.Review.

173.Delbue S, Guerini FR, Mancuso R, Caputo D, Mazziotti R, Saresella M, FerranteP. JC virus viremia in interferon-beta-treated and untreated Italian multiple sclerosis patients and healthycontrols. J Neurovirol. 2007;13(1):73-7.

174.Vidal JE, Fink MC, Cedeno-Laurent F, Delbue S, Ferrante P, Dauar RF, Filho FB,Nogueira RS, Calore EE, Pannuti CS, Trujillo JR, de Oliveira AC. BKvirus associated meningoencephalitis in an AIDS patient treated with HAART.AIDS Res Ther. 2007 Jun 8;4:13.

175. Guerini FR, Delbue S, Zanzottera



M, Agliardi C, Saresella M, Mancuso R, Maserati R, Marchioni E, Gori A,Ferrante P. Analysisof CCR5, CCR2, SDF1 and RANTES gene polymorphisms in subjects with HIV-relatedPML and not determined leukoencephalopathy. Biomed Pharmacother. 2007 May22;

176.Wang JY, Gualco E, Peruzzi F, Sawaya BE, Passiatore G, Marcinkiewicz C,Staniszewska I, Ferrante P, Amini S, Khalili K, Reiss K. Interactionbetween serine phosphorylated IRS-1 and beta1-integrin affects the stability ofneuronal processes. J Neurosci Res.2007 Aug 15;85(11):2360-73.

177. Delbue S, Marchioni E, Sotgiu G,Saresella M, Tavazzi E, Colombo E, Guerini FR, Maserati R, Sinforiani E,Schifino MR, Ferrante P. Longitudinal study of two cases of progressivemultifocal leukoencephalopathy with a clinical benign evolution. J Neurovirol. 2007, 13: 268-73.

178. D'Alfonso S, Bolognesi E, GueriniFR, Barizzone N, Bocca S, Ferrante D, Castelli L, Bergamaschi L, Agliardi C,Ferrante P, Naldi P, Leone M, Caputo D, Ballerini C, Salvetti M, Galimberti D,Massacesi L, Trojano M, Momigliano-Richiardi P.A sequence variation in theMOG gene is involved in multiple sclerosis susceptibility in Italy. Genes Immun. 2007 Oct 11.

179. Guerini FR, Fusco C, Mazzi B, FavoinoB, Nocera G, Agliardi C, Ceresa D, Valentino M, Mininni D, Zanzottera M,Ferrante P, Lombardi ML. HLA-Cw allelefrequencies in noerthern and southern Italy. Transpl Immunol. 2008, 18: 286-289.

180. Romagnoli L, Sariyer IK, Tung J, Feliciano M,Sawaya BE, Del Valle L, Ferrante P, Khalili K, Safak M, White MK. Earlygrowth response-1 protein is induced by JC virus infection and binds andregulates the JC virus promoter. Virology. 2008, 375(2):331-41

181. Tremolada S, Delbue S, Ferrante P.Viral infections of the fetus and newborninfant. Pediatr Med Chir. 2008, 30(4):177-91. Review.

182. Delbue S, Tremolada S, BranchettiE, Elia F, Gualco E, Marchioni E, Maserati R, Ferrante P. First identification and molecular characterization of lymphotropic polyomavirusin peripheral blood from patients with leukoencephalopathies. J ClinMicrobiol. 2008;46(7):2461-2

183. Marchioni E, Bono G, Tavazzi E,Antinori A, Minoli L, Ceroni M; Italian Postinfectious Demyelinating Diseases(IPoDD) Study Group; Italian Study Group of Neuroinfectious Diseases. Recruitment criteria for acute disseminated encephalomyelitisstudies: the need for consensus. Neurol Sci. 2008;29(4):203-4.

184. Tavazzi E, Minoli L, Ferrante P, Scagnelli P,



Del Bue S, Romani A, Ravaglia S, Marchioni E. Varicella zoster virus meningo-encephalo-myelitis in an immunocompetentpatient. Neurol Sci. 2008; 29(4):279-83.

185. Gironi M, Guerini FR, Beghi E,Antonini G, Martinelli-Boneschi F, Ceresa L, Morino S, Agliardi C, Ferrante P,Nemni R. HLA-DRB1 polymorphismsdistribution in chronic dysimmune polyneuropathy. Neuromuscul Disord.2008;18(12):967-9.

186. Delbue S, Branchetti E, BoldoriniR, Vago L, Zerbi P, Veggiani C, Tremolada S, Ferrante P. Presence and expression of JCV early gene large T Antigen in the brainsof immunocompromised and immunocompetent individuals. J Med Virol.2008;80(12):2147-52

187. Mancuso R, Biffi R, Valli M,Bellinvia M, Tourlaki A, Ferrucci S, Brambilla L, Delbue S, Ferrante P, TinelliC, Clerici M. HHV8 a subtype is associatedwith rapidly evolving classic Kaposi's sarcoma. J Med Virol.2008;80(12):2153-60.

188. Saresella M, Marventano I, GueriniFR, Zanzottera M, Delbue S, Marchioni E, Maserati R, Longhi R, Ferrante P,Clerici M. Myelin basic protein-specificT lymphocytes proliferation and programmed cell death in demyelinatingdiseases. Clin Immunol. 2008;129(3):509-17

189. Delbue S, Branchetti E, BertolacciS, Tavazzi E, Marchioni E, Maserati R, Minnucci G, Tremolada S, Vago G,Ferrante P. JC virus VP1 loop-specific polymorphismsare associated with favorable prognosis for progressive multifocalleukoencephalopathy. J Neurovirol. 2009 Jan;15(1):51-6.

190. Visco C, Marchioni E, Pomponi F,Ferrante P, Delbue S, Pellizzer G, Rodeghiero F. Progressive multifocal leuconcephalopathy and autoimmune haemolyticanemia in chronic lymphocytic leukaemia: more than a fortuitous combination? AnnHematol. 2009;88(2):189-91

191. Cortese A, Tavazzi E, Delbue S,Alfonsi E, Pichiecchio A, Ceroni M, Ferrante P, Marchioni E. Varicella zoster virus-associatedpolyradiculoneuritis. Neurology. 2009;73(16):1334-5

192. Guerini FR, Calabrese E, AgliardiC, Zanzottera M, Franceschi M, Grimaldi LM, Nemni R, Ferrante P. Association study of the HLA-A2 allele inItalian Alzheimer disease patients. Neurobiol Aging. 2009;30(12):2082-3.

193. Tremolada S, Delbue S, CastagnoliL, Allegrini S, Miglio U, Boldorini R, Elia F, Gordon J, Ferrante P. Mutations in the external loops of BK virus



VP1 and urine viral load in renal transplant recipients. J Cell Physiol.2010;222(1):195-9.

194. Delbue S, Tremolada S, Elia F,Carloni C, Amico S, Tavazzi E, Marchioni E, Novati S, Maserati R, Ferrante P. Lymphotropic polyomavirus is detected in peripheralblood from immunocompromised and healthy subjects. J Clin Virol. 2010;47(2):156-60.

195. Tremolada S, Delbue S, Larocca S,Carloni C, Elia F, Khalili K, Gordon J, Ferrante P. Polymorphisms of the BK virus subtypes and their influence on viral invitro growth efficiency. Virus Res. 2010;149(2):190-6.

196. Mancuso R, Hernis A, Cavarretta R,Caputo D, Calabrese E, Nemni R, Ferrante P, Delbue S, Clerici M. Detection of viral DNA sequences in thecerebrospinal fluid of patients with multiple sclerosis. J Med Virol. 2010;82(6):1051-7.

197. Tavazzi E, Bargiggia V, PichiecchioA, Delbue S, Maserati R, Bastianello S, Ferrante P, Minoli L, Ricevuti G,Ceroni M, Marchioni E. HIV-related acuteinflammatory leukoencephalopathy of undetermined origin: review of theliterature. International Journal of Immunopathology and Pharmacology,2010; 23: 693-700

198. Tremolada S, Delbue S, FerraressoM, Carloni C, Elia F, Larocca S, Bortolani E, Ferrante P. Search for genomic sequences of microbial agents in atheroscleroticplaques. International Journal of Immunopathology and Pharmacology,2011 Jan-Mar;24(1):243-6

199. Tavazzi E, Magrassi L, Maccabruni A, Bargiggia V,Pichiecchio A, Delbue S, Ferrante P, Minoli L,Marchioni E. Acute transientinflammatory leukoencephalopathy in HIV. Neurol Sci. 2011Oct;32(5):899-902.

200. Zucchella C, Sinforiani E, Gavazzi E, Delbue S,Novati S, Macerati R, Ceroni M, Bastianello S, Minoli L, Ferrante P, MarchioniE. Neuropsychological evaluation andfollow up in jcv- and non-jcv-related leukoencephalopathies in HIV infection.Neurol Sci. 2011 Oct;32(5):833-9

201.Delbue S, Comar M,Ferrante P. Review on the relationshipbetween human polyomaviruses-associated tumors and host immune system. Clinical and Developmental Immunology. 2012,2012:542092

202.Delbue S, Elia F, Carloni C,Tavazzi E, Marchioni E, Carluccio S, Signorini L, Novati S, Maserati R,Ferrante P. JC virus load incerebrospinal fluid and transcriptional control region rearrangements maypredict the clinical course of progressive multifocal leukoencephalopathy. J Cell Phys. 2012, 227



(10):3511-7

203.Zanin V, Delbue S, Marcuzzi A,Tavazzi E, Del Savio R, Crovella S, Marchioni E, Ferrante P, Comar M. Specific protein profile in cerebrospinalfluid from HIV-1-positive cART-treated patients affected by neurologicaldisorders. J Neurovirol. 2012, 18(5):416-22.

204.Delbue S, Ferraresso M, EliaF, Belingheri M, Carloni C, Signorini L, Carluccio S, Dallari S, Ghio L,Ferrante P. Investigation ofpolyomaviruses replication in pediatric patients with nephropathy receivingrituximab J Med Virol 2012, 84 (9):1464-70

205. Pacifici M, Delbue S, Ferrante P, Jeansonne D, Kadri F, Nelson S,Velasco-Gonzalez C, Zabaleta J, Peruzzi. Cerebrospinalfluid miRNA profile in HIV-encephalitis. J Cell Physiol. 2013,228(5):1070-5

206.Delbue S, Carluccio S,Ferrante P. The long and evolving relationship between viruses and multiplesclerosis, Future Virology, 2012,7:9,871-883

207.Marchioni E, Ravaglia S, Montomoli C, Tavazzi E,Minoli L, Baldanti F, Furione M, Alfonsi E, Bergamaschi R, Romani A, Piccolo L,Zardini E, Bastianello S, Pichiecchio A, Ferrante P, Delbue S, Franciotta D,Bono G, Ceroni M. Post-infectiousneurological sindrome: a prospective color study, Neurology, 2013,80(10):882-9

208. Delbue S, Ferraresso M. JC Polyomavirus Infections in TransplantPatients. J Transplant Technol Res 2:e114.

209.Comar M, Delbue S, Lepore L,Martelossi S, Radillo O, Ronfani L, D’Agaro P, Ferrante P. Latent viral infections in young patients with inflammatory diseasestreated with biological agents: prevalence of JC virus genotype 2. Journalof Medical Virology, 2013, 85(4):716-22

210.Delbue S, Ferraresso M, GhioL, Carloni C, Carluccio S, Belingheri M, Edefonti A, Ferrante P. A review on JC Virus infection in kidneytransplant recipients Clinical and Developmental Immunology, 2013:926391

211.Zanotta N, Delbue S, Rossi T,Pelos G, D’Agaro P, Ferrante P, Comar M. Molecularepidemiology of JCV genotypes and risk of Progressive MultifocalLeukoencephalopathy in North Italy population. Journal of Medical Virology,2013, in press

212. Delbue S, Matei DV, Carloni



C, Pecchenini V, Carluccio S, Villani S, Tringali V, Brescia A, Ferrante P. Evidence supporting the association ofpolyomavirus BK genome with prostate cancer.Med Microbiol Immunol. 2013, in press

Projects Representative

examples

• NIH R01 MH072528 from6/05 to 5/10

“Pathogenesis of

leukoencephalopathies in HIV+ patients” (Principal Investigator)

• NIH R21 MH068360-01 (Program

Project) from4/03 to 3/05

"Novel Leukoencephalopathy in

HAART-treated HIV-1 + Patients." (Principal Investigator)

• Cariplo Foundation from12/02 to 11/04

"

Study of the possible role of JC virus in human brain tumors ”. (PrincipalInvestigator)

• Italian Minister of Scientific Research

and University from12/01 to 11/03

"Production of innovative

molecules with antinflammatory and antitumoral activity by advanced chemicaltechniques" (Principal

Investigator)

Memberships

Other Relevant Information


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