pesticide resides in food 2013
TRANSCRIPT
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FAOPLANT
PRODUCTIONAND PROTECTION
PAPER
219
ISSN 0259-2517
Pesticide residuesin food 2013
REPORT2013
Joint FAO/WHO Meeting on Pesticide Residues
Food and Agriculture Organization of
the United Nations
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WORLD HEALTH ORGANIZATIONFOOD AND AGRICULTURE ORGANIZATION OF THE UNITED NATIONSRome, 2014
Pesticide residues in food 2013Joint FAO/WHO Meetingon Pesticide Residues
FAOPLANT
PRODUCTIONAND PROTECTION
PAPER
219
Report of the Joint Meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and the WHO Core Assessment Group on Pesticide ResiduesGeneva, Switzerland, From 17 to 26 September 2013
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The designations employed and the presentation of material in this information product do not imply the expression of any opinion whatsoever on the part of the Food and Agriculture Organization of the United Nations (FAO) concerning the legal or development status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. The mention of specific companies or products of manufacturers, whether or not these have been patented, does not imply that these have been endorsed or recommended by FAO in preference to others of a similar nature that are not mentioned.
The views expressed in this information product are those of the author(s) and do not necessarily reflect the views or policies of FAO.
ISBN 978-92-5-108043-6 (print)E-ISBN 978-92-5-108044-3 (PDF)
© FAO, 2014
FAO encourages the use, reproduction and dissemination of material in this information product. Except where otherwise indicated, material may be copied, downloaded and printed for private study, research and teaching purposes, or for use in non-commercial products or services, provided that appropriate acknowledgement of FAO as the source and copyright holder is given and that FAO’s endorsement of users’ views, products or services is not implied in any way.
All requests for translation and adaptation rights, and for resale and other commercial use rights should be made via www.fao.org/contact-us/licence-request or addressed to [email protected].
FAO information products are available on the FAO website (www.fao.org/publications) and can be purchased through [email protected].
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2.2
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(FAO Rapporteur)
(FAO Chairman)
(WHO Chairman)
(WHO Rapporteur)
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,
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O
c
C
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N
O
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T C
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2.2
EFSA Journal
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ooo
Principles and Methods for the Risk Assessment of Chemicals in Food
EFSA Journal
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but units of fresh plant products or whole eggs should not be cut or broken.”
CAC/GL 33-1999.
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o
o
Part A
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o
o
o
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Background
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Evaluation of clothianidin and thiamethoxam by JMPR
Evaluation of clothianidin by the EU
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Comments by JMPR
Background
N-
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Evaluation of the new reproductive toxicity study with MPP
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Overview of toxicity data on glufosinate-ammonium, NAG and MPP
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—
— —
Assessment of relative toxic potencies of NAG, MPP and MPA compared with glufosinate-ammonium
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Conclusion
Recalculation of STMR, HR, PF, STMR-P and HR-P values
PCH3OH
O
O
OH PCH3OH
O
OH
O
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Dietary risk assessment
Long-term intake
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Short-term intake
Background
Reregistration Eligibility Decision for Propylene Oxide
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Propylene oxide
Concern
Response
Propylene chlorohydrin
Concern
Response
Food and Chemical Toxicology
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Propylene bromohydrin
Concern
in vivo
Response
Concern
Response
E. coli Short-term tests for chemical carcinogens
Food and Cosmetics Toxicology
Journal of Toxicology and Environmental HealthSalmonella
Environmental Mutagenesis
Salmonella Mutation ResearchEnvironmental Health
Perspectives
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Assessment of risk from long-term dietary intake
New evaluations
Periodic Re-evaluations
Evaluations
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Chlorpyrifos-methyl
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Assessment of risk from short-term dietary intake
New evaluations
Periodic Re-evaluations
Evaluations
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Possible risk assessment refinement when the IESTI exceeds the ARfD
Glufosinate-ammonium in soya bean
Triazophos in rice
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Methods of residue analysis
Results of supervised residue trials on crops
Pulses
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Potato
Barley and oats
Sorghum
Coffee beans
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Legume animal feeds
Pea hay or pea fodder (dry)
Pea vines (green)
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Straw and fodder (dry) of cereal grains
Cereal forage (green)
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Oats forage (green)
Sorghum forage (green)
Fate of residues during processing
Farm animal dietary burden
Estimated maximum and mean dietary burdens of farm animals
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Animal commodity residue levels
Long-term intake
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Short-term intake
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NH
S
N
O
O
O
O
NSO2N
H
OH
O
NSO2N
HOH
O
NSO2N
H
conjugates-O
O
NSO2N
HO-conjugates
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O
NSO2N
COOHO
OH
OH
OH
GlcGlc
Animal metabolism
Laboratory animals
Lactating goats
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Laying hens
Plant metabolism
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Environmental fate in soil
Aerobic soil metabolism
Water/sediment dissipation
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Soil Photolysis
Confined rotational crop
Methods of analysis
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Stability of residues in stored analytical samples
Definition of the residue
bentazone
Results of supervised residue trials on crops
Onion, bulb
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Spring onion
Cucumber
Sweet corn (corn-on-the-cob)
Peas (pods and succulent = immature seeds)
Beans, except broad bean and soya bean
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Beans, shelled
Peas (dry)
Beans (dry)
Soya bean (dry)
Potato
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Cereals grains
Barley, oats and wheat
Maize
Rice
Sorghum
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Oilseeds
Linseed
Peanut
Herbs
Sugar beet
Animal feedstuffs
Pea vines (green)
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Pea hay
Bean forage (green)
Soy bean forage (green)
Soya bean straw and fodder
Alfalfa forage (green)
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Alfalfa fodder
Clover
Clover hay or fodder
Peanut fodder
Grass forage
Hay or fodder (dry) of grasses
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Straw and fodder (dry) of cereal grain
Barley, millet, oats, rye, triticale, and wheat straw and fodder, dry
Maize fodder
Rice straw, dry
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Fate of residues during processing
Residues in animal commodities
Estimated maximum and mean dietary burdens of farm animals
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Long term intake
Short-term intake
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N-RS SR
Biochemical aspects
N
Toxicological data
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Toxicological data on metabolites and/or degradates
S S RR R S
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Human data
Levels relevant to risk assessment of benzovindiflupyr
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Estimate of acceptable daily intake
Estimate of acute reference dose
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Information that would be useful for the continued evaluation of the compound
Critical end-points for setting guidance values for exposure to benzovindiflupyr
Absorption, distribution, excretion and metabolism in mammals
Acute toxicity
Short-term studies of toxicity
Long-term studies of toxicity and carcinogenicity
Genotoxicity
Reproductive toxicity
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Developmental toxicity
Neurotoxicity
Other toxicological studies
Medical data
Summary
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N
Biochemical aspects
Toxicological data
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Human data
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Levels relevant to risk assessment of bixafen
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Estimate of acceptable daily intake
Estimate of acute reference dose
Information that would be useful for the continued evaluation of the compound
Critical end-points for setting guidance values for exposure to bixafen
Absorption, distribution, excretion and metabolism in mammals
Acute toxicity
Short-term studies of toxicity
Long-term studies of toxicity and carcinogenicity
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Genotoxicity
Reproductive toxicity
Developmental toxicity
Neurotoxicity
Other toxicological studies
Medical data
Summary
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NH
OH
Cl
Cl
N
N
F FO
S
NH2CH3
O
OH
O
O
OOH
OH
OH
OH
NH
Cl
Cl
N
N
F FO
SCH3
CH3
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O
OH
OH
OHO
O
NH
F
Cl
Cl
N
N
F FO
CH3
SO O
OH
or isomer
NH
F
Cl
Cl
N
NH
F FO
NH
F
Cl
Cl
N
NH
F FO
glucuronide
NH
F
Cl
Cl
N
NH
F FO
glycoside
NH
F
Cl
Cl
N
NH
F FO
glycosideOH
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NH
F
Cl
Cl
N
NH
F FO
pentosideOH
NNH
F
Cl
Cl
N
F FO
OH
NH
OH
Cl
Cl
N
NH
F FO
S
NH2
O
OH
NH2N
NCH3
F FO
OHN
NH
F FO
proposal for tautomer 1
OHNH
N
F FO
proposal for tautomer 2
OHNH
NH
O O
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Animal metabolism
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Plant metabolism
Environmental fate in soil
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Methods of residue analysis
Stability of residues in stored analytical samples
Definition of the residue
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bixafen
sum of bixafen and N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1H-pyrazole-4-carboxamide (bixafen-desmethyl), expressed as bixafen
Results of supervised residue trials on crops
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Rape seed
Barley and oats
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Wheat, rye, triticale and spelt
Animal feeds
Oilseed rape, forage
Barley, oats, rye, triticale and wheat – forage of cereals
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Barley, oats, rye, triticale and wheat – straw and fodder
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Residues in rotational crops
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Fate of residues during processing
Residues in animal commodities
Farm animal feeding studies
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Estimated maximum and mean dietary burdens of livestock and animal commodities maximum residue levels
bixafen
sum of bixafen and N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1H-pyrazole-4-carboxamide (bixafen-desmethyl), expressed as bixafen
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Results from supervised residue trials on crops
Berries and other small fruits
Avocado
Pomegranate
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Radish tops
Legume vegetables
Soya bean, dry
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Root and tuber vegetables
Globe artichoke
Rice
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Cereals, except rice
Rape and sunflower seeds
Coffee
Hops
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Animal feeds
Fate of residues during processing
Residues in animal commodities
Farm animal dietary burden
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Animal commodity maximum residue level
Long-term intake
Short-term intake
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Biochemical aspects
Toxicological data
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Levels relevant to risk assessment of chlorfenapyr
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Information that would be useful for the continued evaluation of the compound
Critical end-points for setting guidance values for exposure to chlorfenapyr
Acute toxicity
Short-term studies of toxicity
Genotoxicity
Developmental toxicity
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et al
et al
![Page 113: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/113.jpg)
Long-term intake
Short-term intake
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Biochemical aspects
CC
N N
O
H
Toxicological data
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Toxicological data on metabolites and/or degradates
bN
Human data
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Levels relevant to risk assessment of cyantraniliprole
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Estimate of acceptable daily intake
Estimate of acute reference dose
Information that would be useful for the continued evaluation of the compound
Critical end-points for setting guidance values for exposure to cyantraniliprole
Absorption, distribution, excretion and metabolism in mammals
Acute toxicity
Short-term toxicity
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Long-term toxicity and carcinogenicity
Genotoxicity
Reproductive toxicity
Developmental toxicity
Neurotoxicity
Immunotoxicity
Medical data
Summary
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N
N NCH3
NH
O
NH O
CH3
Br
Cl
N
H
H
H
NH
O
NN
N
Br
Cl
NH2O
N
N
N
ON
N
N
Br
Cl
N
O
NH2
ONH
NH
ON
N
NCl
Br
![Page 121: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/121.jpg)
H
H
H
Hb
H
Animal metabolism
NH
ONH2
ON
N
NCl
Br
O
NH2
NH
N
O NN
N
Br
Cl
N
NH
ON
N
N
Br
Cl
NH
OH
O
N
N
N
Cl
ON
NN
N
NH
O Cl
BrNH O
OHN
NH
NH
O
N
Br
![Page 122: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/122.jpg)
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Plant metabolism
Cotton
Lettuce
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Tomato
Rice
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Environmental fate
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Hydrolysis
Photolysis
Aerobic soil metabolism
Soil dissipation
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Water/sediment dissipation
Residues in succeeding crops
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Methods of analysis
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Stability of pesticide residues in stored analytical samples
Definition of the residue
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): cyantraniliprole
cyantraniliprole
sum of cyantraniliprole and IN-J9Z38, expressed as cyantraniliprole
sum of cyantraniliprole, 2-[3-Bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazol-5-yl]-3,4-dihydro-3,8-dimethyl-4-oxo-6-quinazolinecarbonitrile [IN-J9Z38], 2-[3-Bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazol-5-yl]-1,4-dihydro-8-methyl-4-oxo-6-quinazolinecarbonitrile [IN-MLA84], 3-Bromo-1-(3-chloro-2-pyridinyl)-N-[4-cyano-2-(hydroxymethyl)-6-[(methylamino)carbonyl]phenyl]-1H-pyrazole-5-carboxamide [IN- N7B69] and 3-Bromo-1-(3-chloro-2-pyridinyl)-N-[4-cyano-2[[(hydroxymethyl)amino]carbonyl]-6-methylphenyl]-1H-pyrazole-5-carboxamide [IN- MYX98], expressed a cyantraniliprole
Results of supervised residue trials on crops
![Page 131: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/131.jpg)
Pome fruits
Stone fruits
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Bush berries
Bulb vegetables
Brassica (cole or cabbage) vegetables
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Fruiting vegetables, Cucurbits
Fruiting vegetables, other than Cucurbits
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Leafy vegetables (including Brassica leafy vegetables)
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Root and tuber vegetables
Stalk and stem vegetables
Rice
Tree nuts
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Oilseeds
Seed for beverages and sweets
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Estimation of residues in plant commodities grown as potential succeeding crops
Leafy vegetables (including Brassica leafy vegetables)
Root and tuber vegetables
Miscellaneous fodder root crops
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Legume animal feeds
Cereal and grass forages, straws and hays
Miscellaneous fodder leaf crops
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Fate of residues during processing
![Page 140: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/140.jpg)
Residues in animal commodities
Farm animal dietary burden
Estimated maximum and mean dietary burdens of farm animals
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Farm animal feeding studies
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Animal commodity maximum residue levels
![Page 143: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/143.jpg)
cyantraniliprole
cyantraniliprole
sum of cyantraniliprole and 2-[3-Bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazol-5-yl]-3,4-dihydro-3,8-dimethyl-4-oxo-6-quinazolinecarbonitrile
cyantraniliprole, 2-[3-Bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazol-5-yl]-3,4-dihydro-3,8-dimethyl-4-oxo-6-quinazolinecarbonitrile, 2-[3-Bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazol-5-yl]-1,4-dihydro-8-methyl-4-oxo-6-quinazolinecarbonitrile, 3-Bromo-1-(3-chloro-2-pyridinyl)-N-[4-cyano-2-(hydroxymethyl)-6-[(methylamino)carbonyl]phenyl]-1H-pyrazole-5-carboxamide and 3-Bromo-1-(3-chloro-2-pyridinyl)-N-[4-cyano-2[[(hydroxymethyl)amino]carbonyl]-6-methylphenyl]-1H-pyrazole-5-carboxamide
![Page 144: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/144.jpg)
Long-term intake
Short-term intake
![Page 145: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/145.jpg)
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Methods of analysis
Results from supervised residue trials on crops
Fate of residues in processing
![Page 147: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/147.jpg)
cyproconazole
Long-term intake
Short-term intake
![Page 148: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/148.jpg)
Methods of analysis
Stability of residues in stored analytical samples
Results of supervised residue trials on crops
Citrus fruits
Pome fruits
![Page 149: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/149.jpg)
Berries and other small fruits
.,
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Assorted tropical and sub-tropical fruits – inedible peel
Avocado
Kiwifruit
Litchi (lychee)
Brassica vegetables
Cabbages, Head
Flowerhead Brassicas
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Fruiting vegetables, Cucurbits
Fruiting vegetables, other than Cucurbits
![Page 152: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/152.jpg)
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Brassica leafy vegetables
Leafy vegetables, except brassica leafy vegetables
Legume vegetables
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Beans (dry)
Carrots
Radish
![Page 155: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/155.jpg)
Herbs
Processing studies
![Page 156: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/156.jpg)
Residues in animal commodities
Farm animal dietary burden
Animal commodity maximum residue levels
Mammals
![Page 157: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/157.jpg)
Poultry
Long-term intake
Short-term intake
![Page 158: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/158.jpg)
Dicamba
Sum of dicamba and 5-OH dicamba expressed as dicamba
Sum of dicamba and DCSA expressed as dicamba
Method of analysis
m/z m/zm/z
Results of supervised residue trials on crops
Soya bean (dry)
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Soya bean forage and hay
Fate of residues during processing
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Residues in animal commodities
Dicamba.
Sum of dicamba and 5-OH dicamba expressed as dicamba
Dicamba and 3,6-dichlorosalicylic acid (DCSA) expressed as dicamba.
Long-term intake
Short-term intake
![Page 161: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/161.jpg)
![Page 162: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/162.jpg)
Methods of analysis
Stability of residues in stored analytical samples
![Page 163: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/163.jpg)
Results of supervised residue trials on crops
Citrus fruits
Pome fruits
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Grapes
Bulb vegetables
Onion, bulb
Spring onion
.
Brassica (cole or cabbage) vegetables, Head cabbages, Flowerhead cabbages
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Fruiting vegetables, Cucurbits
Melons
Cucumber, summer squash
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Fruiting vegetables, other than Cucurbits
Potato (post-harvest treatment)
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Ginseng
Animal feed
Fate of residues during processing
![Page 168: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/168.jpg)
Residues in animal commodities
Estimated dietary burdens of farm animals
Estimated residues in animal commodities
Cattle
![Page 169: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/169.jpg)
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Poultry
difenoconazole
sum of difenoconazole and 1-[2-chloro-4-(4-chloro-phenoxy)-phenyl]-2-(1,2,4-triazol)-1-yl-ethanol), expressed as difenoconazole
![Page 171: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/171.jpg)
Long-term intake
Short-term intake
![Page 172: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/172.jpg)
Biochemical aspects
Toxicological data
![Page 173: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/173.jpg)
![Page 174: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/174.jpg)
Toxicological data on metabolites and/or degradates
![Page 175: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/175.jpg)
Human data
Levels relevant to risk assessment of diquat
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Estimate of acceptable daily intake
Estimate of acute reference dose
Information that would be useful for the continued evaluation of the compound
Critical end-points for setting guidance values for exposure to diquat
Absorption, distribution, excretion and metabolism in mammals
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Acute toxicity
Short-term studies of toxicity
Long-term studies of toxicity and carcinogenicity
Genotoxicity
Reproductive toxicity
Developmental toxicity
Neurotoxicity
Other toxicological studies
Medical data
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Summary
Animal metabolism
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Plant metabolism
Application prior to crop emergence
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Crop desiccation
Environmental fate
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Methods of analysis
Stability of pesticide residues in stored analytical samples
Definition of the residue
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diquat ion
Results of supervised residue trials on crops
Tree crops (application to weeds)
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Berries and other small fruit (application to weeds)
Strawberries
Fruiting vegetables other than Cucurbits
Pulses (pre-harvest desiccation)
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Carrots (directed application for weed control)
Potato (pre-harvest desiccation)
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Rape seed, (pre-harvest desiccation)
Sunflower seed (pre-harvest desiccation)
Animal feeds
Pea fodder (pre-harvest desiccation)
Fate of residues during processing
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Residues in animal commodities
Farm animal feeding studies
Animal commodity maximum residue levels
Animal commodity maximum residue levels
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Diquat ion.
Long-term intake
Short-term intake
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HRPT
S
S
O
O
N
N
![Page 189: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/189.jpg)
OHO
O
O
O
OHOH
O
O
OS
S CN
CN
OH OHO O
OS CN
CN O
OS
S
CONH2
CONH2
b ib b
Animal metabolism
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in vitro
in vivo
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Plant metabolism
Environmental fate
Methods of analysis
Stability of residues in stored analytical samples
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Definition of the residue
per se
: Dithianon.
Results of supervised residue trials on crops
Citrus fruits
Citrus sphaerocarpa
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Pome fruits
Stone fruits
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Grapes
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Currants
Almonds
Hops, dry
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Fate of residues during processing
Nature of residues
Level of residues
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Farm animal dietary burden
Estimated maximum and mean dietary burdens of farm animals
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Farm animal feeding and metabolism studies
Animal commodity maximum residue levels
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Dithianon
Long-term intake
Short-term intake
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S
R
Biochemical aspects
Toxicological data
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Toxicological data on metabolites and/or degradates
S
SS
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Human data
Levels relevant to risk assessment of fenamidone
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Levels relevant to risk assessment of fenamidone metabolites based on studies conducted in rats
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S
S
S
Estimate of acceptable daily intake
Estimate of acute reference dose
Information that would be useful for the continued evaluation of fenamidone
Critical end-points for setting guidance values for exposure to fenamidone
Absorption, distribution, excretion and metabolism in mammals
Acute toxicity
Short-term studies of toxicity
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Long-term studies of toxicity and carcinogenicity
Genotoxicity
Reproductive toxicity
Developmental toxicity
Neurotoxicity
Toxicological studies on RPA 412636
Toxicological studies on RPA 410193
Toxicological studies on RPA 412708
Medical data
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Summary
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Results of supervised residue trials on crops
Citrus fruits
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Fate of residues during processing
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Residues in animal commodities
Farm animal feeding studies
Animal commodity maximum residue levels
fenbuconazole
Long-term intake
Short-term intake
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Results of supervised residue trials on crops
Stone fruits
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Strawberry
Avocado
Cucumber
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Common beans (pods and/or immature seeds)
Potato
Mints
Legume animal feeds
Bean forage
Fate of residues during processing
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Residues in animal commodities
Estimation of dietary burdens
Residues in milk and mammalian tissues
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fenpyroximate
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Long-term intake
Short-term intake
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Methods of analysis
Results from supervised residue trials on crops
Lemon
Avocado
Pineapple
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Fruiting vegetables, Cucurbits
Tomato
Peppers (Bell & Non-Bell)
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Leafy vegetables
Potato
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Radish
Legume vegetables
Beans (dry)
Herbs
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Ginseng
Residues in processed commodities
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Residues in animal commodities
Farm animal dietary burden
Animal feeding study
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Animal commodity maximum residue levels
fludioxonil
Long-term intake
Short-term intake
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Biochemical aspects
Toxicological data
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Salmonella typhimurium
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Toxicological data on metabolites and/or degradates
S. typhimurium
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Human data
Levels relevant to risk assessment of fluensulfone
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Estimate of acceptable daily intake
Estimate of acute reference dose
Information that would be useful for the continued evaluation of the compound
Critical end-points for setting guidance values for exposure to fluensulfone
Absorption, distribution, excretion and metabolism in mammals
Acute toxicity
![Page 234: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/234.jpg)
Short-term studies of toxicity
Long-term studies of toxicity and carcinogenicity
Genotoxicity
Reproductive toxicity
Developmental toxicity
Neurotoxicity
Other toxicological studies
Medical data
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Summary
![Page 236: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/236.jpg)
Methods of analysis
Stability of pesticide residues in stored analytical samples
Results of supervised residue trials on crops
Brassica vegetables
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Broccoli
Cabbages, Head
Leafy vegetables
Mustard greens
Brassica (cole or cabbage) vegetables, Head cabbages, Flowerhead Brassicas; and Brassica leafy vegetables
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Residues in animal commodities
Estimation of dietary burdens
Residues in milk and mammalian tissues
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Residues in eggs and poultry tissues
Long-term intake
![Page 240: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/240.jpg)
Short-term intake
![Page 241: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/241.jpg)
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gatN
gatgat
N N N
N
Plant metabolism
gat
N
gat NN-
gat
![Page 243: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/243.jpg)
Methods of Analysis
Stability of pesticide residues in stored analytical samples
Definition of the residue
gat N N-gat N
gat
gat
the sum of glyphosate and N-acetyl-glyphosate expressed as glyphosate glyphosate
sum of glyphosate and N-acetyl-glyphosate, expressed as glyphosateglyphosate
glyphosate, N-acetyl-glyphosate, AMPA and N-acetyl AMPA, expressed as glyphosate
Results of supervised residue trials on crops
gat
N
gatgat N
N
gat
![Page 244: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/244.jpg)
Fate of residues during processing
Residues in animal commodities
Animal commodity maximum residue levels
sum of glyphosate and N-acetyl-glyphosate, expressed as glyphosateglyphosate
glyphosate, N-acetyl-glyphosate, AMPA and N-acetyl AMPA, expressed as glyphosate
![Page 245: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/245.jpg)
sum of glyphosate and N-acetylglyphosate, expressed as glyphosate
glyphosate, N-acetylglyphosate, AMPA and N-acetyl AMPA, expressed as glyphosate
Long-term intake
N NN
N
Short-term intake
![Page 246: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/246.jpg)
RS
Biochemical aspects
Toxicological data
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Human data
![Page 248: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/248.jpg)
Levels relevant to risk assessment of imazapic
![Page 249: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/249.jpg)
Estimate of acceptable daily intake
Estimate of acute reference dose
Information that would be useful for the continued evaluation of the compound
Critical end-points for setting guidance values for exposure to imazapic
Absorption, distribution, excretion and metabolism in mammals
Acute toxicity
Short-term studies of toxicity
Long-term studies of toxicity and carcinogenicity
Genotoxicity
![Page 250: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/250.jpg)
Reproductive toxicity
Developmental toxicity
Neurotoxicity
Immunotoxicity
Medical data
Summary
![Page 251: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/251.jpg)
Animal metabolism
Metabolism of imazapic in rat
Metabolism of imazapic in lactating goats
Imazapic
CL 263284
![Page 252: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/252.jpg)
Metabolism of imazapic in laying hens
Plant metabolism
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Environmental fate
Aerobic soil metabolism
Photodegradation
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Hydrolysis
Residues in succeeding crops
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Methods of analysis
Stability of residues in stored analytical samples
Definition of the residue
![Page 256: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/256.jpg)
Imazapic.
Results of supervised residue trials on crops
Soya bean (dry)
Maize
Rice
![Page 257: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/257.jpg)
Wheat
Sugar cane
Peanut
Rape seed
![Page 258: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/258.jpg)
Animal feed
Peanut fodder
Wheat straw and fodder, dry, and forage
Hay or fodder (dry) of grasses
![Page 259: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/259.jpg)
Rape seed forage
Fate of residues during processing
High temperature hydrolysis
Processing
Residues in animal commodities
Estimation of dietary burdens
Residues in milk and cattle tissues
![Page 260: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/260.jpg)
Residues in eggs and poultry tissues
![Page 261: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/261.jpg)
Imazapic.
Long-term intake
Short-term intake
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Biochemical aspects
Toxicological data
![Page 263: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/263.jpg)
Toxicological data on metabolites and/or degradates
Human data
![Page 264: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/264.jpg)
Levels relevant to risk assessment of imazapyr
![Page 265: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/265.jpg)
Estimate of acceptable daily intake
Estimate of acute reference dose
Information that would be useful for the continued evaluation of the compound
Critical end-points for setting guidance values for exposure to imazapyr
Absorption, distribution, excretion and metabolism in mammals
Acute toxicity
Short-term studies of toxicity
Long-term studies of toxicity and carcinogenicity
Genotoxicity
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Reproductive toxicity
Developmental toxicity
Neurotoxicity
Other toxicological studies
Medical data
Summary
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RS
H
H
Animal metabolism
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Plant metabolism
Directed sprays to weeds
Weed control
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Imidazolinone-resistant crops
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Environmental fate
Methods of analysis
Stability of residues in stored analytical samples
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Definition of the residue
Imazapyr
Results of supervised residue trials on crops
Pulses
Lentil (dry)
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Soya bean (dry)
Cereal grains
Maize
Rice
Wheat
![Page 273: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/273.jpg)
Grasses for sugar or syrup production
Sugar cane
Oilseeds
Rape seed
Sunflower seed
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Animal feedstuffs
Maize fodder and forage
Maize fodder
Maize forage
Wheat straw and forage
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Wheat straw
Wheat forage
Rape forage
Fate of residues during processing
High temperature hydrolysis
Residues in processed commodities
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Residue in animal commodities
Farm animal dietary burden
Estimated maximum and mean dietary burdens of farm animals
Farm animal feeding studies
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Lactating dairy cows
Animal commodities maximum residue levels
Imazapyr.
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Long-term intake
Short-term intake
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![Page 280: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/280.jpg)
Methods of analysis
Stability of residues in stored analytical samples
Results of supervised residue trials on tea
Fate of residues during storage and processing
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sum of indoxacarb and its R enantiomer
sum of indoxacarb, its R enantiomer and methyl 7-chloro-2,5-dihydro-2-[[[4-(trifluoromethoxy)phenyl] amino]carbonyl]indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylate, expressed as indoxacarb
Long-term intake
Short-term intake
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Biochemical aspects
C
Toxicological data
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O O
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Toxicological data on metabolites and/or degradates
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Human data
Levels relevant to risk assessment of isoxaflutole
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Estimate of acceptable daily intake
Estimate of acute reference dose
Information that would be useful for the continued evaluation of the compound
Critical end-points for setting guidance values for exposure to isoxaflutole
Absorption, distribution, excretion and metabolism in mammals
Acute toxicity
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Short-term studies of toxicity
Long-term studies of toxicity and carcinogenicity
Genotoxicity
Reproductive toxicity
Developmental toxicity
Neurotoxicity
Other toxicological studies
Medical data
Summary
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Chemical name:
CF3
OO SO2CH3
CN
CF3
O SO2CH3
OH
CF3
O
NH2
SO2CH3
CF3
SO2CH3O
NO
![Page 289: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/289.jpg)
CF3
OO SO2CH3
NH2
CF3
OO SO2CH3
OH
CF3
O
NO
Animal metabolism
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Plant metabolism
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Pseudomonas fluorescens
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Environmental fate in soil
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Methods of Analysis
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Stability of pesticide residues in stored analytical samples
Definition of the residue
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sum of isoxaflutole and isoxaflutole diketonitrile, expressed as isoxaflutole.
sum of isoxaflutole and isoxaflutole diketonitrile, expressed as isoxaflutole.
sum of isoxaflutole, isoxaflutole diketonitrile, RPA 205834 (2-aminomethylene-l-cyclopropyl-3-(2-mesyl-4-trifluoromethylphenyl)-propane-1,3-dione) and RPA 207048 (1-cyclopropyl-2-hydroxymethylene-3-(2-mesyl-4-trifluoromethylphenyl)-propane-1,3-dione), including their conjugates, expressed as isoxaflutole.
Results of supervised residue trials on crops
Sweet corn (corn-on-the-cob)
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Pulses
Maize
Sugar cane
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Poppy seed
Legume animal feeds
Forage and fodder of cereal grains and grasses
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Miscellaneous forage and fodder crops
Residues from rotational crops
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Fate of residues during processing
Residues in animal commodities
Livestock feeding studies
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Residues in animal commodities
Cattle
Poultry
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sum of isoxaflutole and isoxaflutole diketonitrile, expressed as isoxaflutole.
sum of isoxaflutole and isoxaflutole diketonitrile, expressed as isoxaflutole.
sum of isoxaflutole, isoxaflutole diketonitrile, RPA 205834 (2-aminomethylene-l-cyclopropyl-3-(2-mesyl-4-trifluoromethylphenyl)-propane-1,3-dione) and RPA 207048 (1-cyclopropyl-2-hydroxymethylene-3-(2-mesyl-4-trifluoromethylphenyl)-propane-1,3-dione), including their conjugates, expressed as isoxaflutole.
![Page 305: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/305.jpg)
Long-term intake
Short-term intake
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Results of supervised residue trials on crops
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malathion.
Long-term intake
Short-term intake
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Methods of analysis
Stability of residues in stored analytical samples
Results of supervised residue trials on crops
Hops
Fate of residues during processing
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: mandipropamid.
Long-term intake
Short-term intake
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Results of supervised residue trials on crops
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Cucurbits with edible peel
Tomato and eggplants
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Barley and oats
Wheat, rye and triticale
Animal feeds
Barley, oats, rye, triticale and wheat forage
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Barley, oats, rye, triticale and wheat straw and fodder of cereals
Fate of residues during processing
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Residues in animal commodities
Livestock dietary burden
Estimated maximum and mean dietary burdens of livestock
Animal commodities, MRL estimation
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penthiopyrad
sum of penthiopyrad and 1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide (PAM), expressed as penthiopyrad
Long-term intake
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Short-term intake
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propiconazole propiconazole plus all metabolites convertible to 2,4-dichlorobenzoic acid,
expressed as propiconazole
Methods of analysis
Stability of residues in stored analytical samples
Results from supervised residue trials on crops
Citrus fruits
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Stone fruits
Tomato
Fate of residues in storage and processing
Effect on the nature of the residues during processing
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Residues in processed commodities
Residues in animal commodities
propiconazole propiconazole plus all metabolites convertible to 2,4-dichlorobenzoic acid, expressed as propiconazole
Long-term intake
Short-term intake
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![Page 324: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/324.jpg)
Methods of analysis
Stability of residues in stored analytical samples
Results of supervised residue trials on crops
Lemon
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Pome fruits
Stone fruits
Berries and other small fruits
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Ginseng
Fate of residue during processing
Residues in animal commodities
Animal commodity maximum residue levels
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pyrimethanil.
Long-term intake
Short-term intake
![Page 328: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/328.jpg)
spirotetramat plus spirotetramat enol, expressed as spirotetramat.
spirotetramat plus the metabolites enol, ketohydroxy, enol glucoside, and monohydroxy, expressed as spirotetramat
spirotetramat enol, expressed as spirotetramat
Methods of analysis
Stability of residues in stored analytical samples
Results of supervised residue trials on crops
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Berries and other small fruits
Blueberries
Cranberry
Assorted tropical and sub-tropical fruits-inedible peel
Banana
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Pineapple
Pomegranate
Bulb vegetables,
Onion, bulb
Spring onion
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Watercress
Artichoke, globe
Coffee beans
Animal feeds
Fate of residues during processing
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Residues in animal commodities
Definition of the residue (for compliance with MRL for plant commodities
Definition of the residue (for estimation of dietary intake)for plant commodities
Definition of the residue (for compliance with MRL and estimation of dietary intake) for animal commodities
Long–term intake
Short-term intake
![Page 333: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/333.jpg)
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Beans (dry)
Common bean (pods and/or immature seeds)
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Carrots
Long-term intake
Short-term intake
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N p
Biochemical aspects
List of abbreviations and chemical names of metabolites used in the report
N p
N p
p
![Page 337: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/337.jpg)
N
Toxicological data
![Page 338: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/338.jpg)
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Toxicological data on metabolites and/or degradates
Human data
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Levels relevant for risk assessment of tolfenpyrad
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Estimate of acceptable daily intake
Estimate of acute reference dose
Information that would be useful for the continued evaluation of the compound
Critical end-points for setting guidance values for exposure to tolfenpyrad
Absorption, distribution, excretion and metabolism in mammals
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Acute toxicity
Short-term studies of toxicity
Long-term studies of toxicity and carcinogenicity
Genotoxicity
Reproductive toxicity
Developmental toxicity
Neurotoxicity
Other toxicological studies
![Page 343: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/343.jpg)
Medical data
Summary
Chemical name and structure
N p
NN C
HN
O
CH3
Cl
CH3O
NN C
HN
O
COOH
Cl
CH3O
![Page 344: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/344.jpg)
NN C
HN
O
COOH
Cl
CH3
OH
O
O CH2NH2HOOC
NN CONH2
Cl
CH3
OH
NN COOH
Cl
CH3
NN
N CHN
O
CH3
Cl
CH3
OH
O
N pN
N CHN
O
CH3
Cl
CH3
O
O
NN
N CHN
O
CH2OH
Cl
CH3O
NN
N CHN
O
CHO
Cl
CH3O
NN C
HN
O
COOH
Cl
CH3O
NN
N CHN
O
CH2OH
Cl
CH3O
OH
NN
N CHN
O
CH2OH
Cl
CH3
O
O
NN C
HN
O
COOH
Cl
CH3
O
O
NN C
HN
O
CH2OH
Cl
CH3
HOOC
O
NN C
HN
O
COOH
Cl
CH3
HOOC
O
N p NN C
HN
O
CH3
Cl
H O
![Page 345: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/345.jpg)
NN
N CHN
O
CH2OH
Cl
H O
NN CONH2
Cl
CH3
NN CONH2
Cl
CH3
OH
p O CONH2H3C
O CONH2HOH2C
O CONH2HOOC
p O COOHH3C
bis O CH2OHHOH2C
O CH2OHHOOC
O COOHHOOC
p O COOC6H11O5H3C
Animal metabolism
Lactating goats
![Page 346: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/346.jpg)
Laying hens
![Page 347: Pesticide Resides in Food 2013](https://reader033.vdocuments.net/reader033/viewer/2022061613/577ccdda1a28ab9e788cce6a/html5/thumbnails/347.jpg)
Plant metabolism
Cabbage
Peach
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Radish
Environmental fate
Soil photolysis
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Aerobic soil metabolism
Confined rotational crop study
Field rotational crop studies
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Methods of analysis
Stability of residues in stored analytical samples
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Definition of the residue
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tolfenpyrad
sum of tolfenpyrad, and free and conjugated PT-CA (4-[4-[(4-chloro-3-ethyl-1-methylpyrazol-5-yl)carbonylaminomethyl]phenoxy]benzoic acid and OH-PT-CA (4-[4-[[4-chloro-3-(1-hydroxyethyl) -1-methylpyrazol-5-yl]carbonylaminomethyl]phenoxy] benzoic acid) (released with alkaline hydrolysis) expressed as tolfenpyrad
Results of supervised residue trials on crops
Tea
Fate of residues during processing
Residues in animal commodities
Farm animal dietary burden
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Farm animal feeding studies
Residues in milk
Residues in cream and skim milk
Residues in muscle
Residues in liver
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Residues in kidney
Residues in fat
Animal commodity maximum residue levels
tolfenpyrad
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Long-term intake
Short-term intake
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triazophos
Methods of analysis
Stability of residues in stored analytical samples
Results of supervised residue trials on crops
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Fate of residues during processing
triazophos
Residues in animal commodities
triazophos
Long-term intake
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Short-term intake
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E No
Biochemical aspects
C T
N
N
NN
Toxicological data
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Toxicological data on metabolites and/or degradates
Human data
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Levels relevant to risk assessment of triflumizole
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Estimate of acceptable daily intake
Estimate of acute reference dose
Information that would be useful for the continued evaluation of the compound
Critical end-points for setting guidance values for exposure to triflumizole
Absorption, distribution, excretion and metabolism in mammals
Acute toxicity
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Short-term studies of toxicity
Long-term studies of toxicity and carcinogenicity
Genotoxicity
Reproductive toxicity
Developmental toxicity
Neurotoxicity
Other toxicological studies
Medical data
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Summary
Cl O
FF
F
OO
OO
O
O
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OCl N
H OH
FF
F
OCl N
H NH2
FF
F
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Animal metabolism
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Plant metabolism
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Environmental fate in soil
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Methods of analysis
Stability of residues in stored analytical samples
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Definition of the residue
For plants and animals
Definition of the residue (for compliance with the MRL and for estimation of dietary intake):
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Results from supervised residue trials on crops
Pome fruits
Apple
Pear
Cherry
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Berries and other small fruits
Grape
Strawberry
Papaya
Brassica (Cole or Cabbage) Vegetables, Head Cabbages, Flowerhead Cabbages
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Broccoli
Cabbage
Fruiting vegetables, Cucurbits
Cucumber-Outdoor Crops
Cucumber-Indoor Crops
Melon
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Summer squash
Tomato
Leafy vegetables (including Brassica leafy vegetables)
Lettuce
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Mustard greens
Swiss chard
Turnip greens
Hazelnuts/Filberts
Hops
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Fate of residues during processing
Residue in animal commodities
Farm animal dietary burden
Estimated maximum and mean dietary burdens of farm animals
Farm animal feeding studies
Lactating dairy cows
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Animal commodities maximum residue levels
Residues analysed as 4-chloro-2-(trifluoromethyl)aniline and expressed as parent triflumizole.
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Long-term intake
Short-term intake
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Biochemical aspects
Toxicological data
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Toxicological data on metabolites and/or degradates
Human data
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Levels relevant to risk assessment of trinexapac-ethyl
Estimate of acceptable daily intake
Estimate of acute reference dose
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Information that would be useful for the continued evaluation of the compound
Critical end-points for setting guidance values for exposure to trinexapac-ethyl
Absorption, distribution, excretion and metabolism in mammals
Acute toxicity
Short-term studies of toxicity
Long-term studies of toxicity and carcinogenicity
Genotoxicity
Reproductive toxicity
Developmental toxicity
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Neurotoxicity
Medical data
Summary
O
O OH
O
O
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HO
O OH
O
O
HO
O
O
O
OH
OHHO
O
O
O
OH
OH
HO
O O
OH
OH
HO
OH
O
O
O
O
O
O
OH
OH
O
OHO
HO
O
HOOH
O
Animal metabolism
Rats
Goats
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Hens
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Summary of animal metabolism
Plant metabolism
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Summary of plant metabolism
Rotational Crops
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Methods of analysis
Stability of pesticide residues in stored analytical samples
Definition of the residue
Animals
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Plants
Results of supervised residue trials on crops
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Cereals - wheat (free trinexapac acid)
Cereals - barley
Cereals - wheat (total residues of trinexapac acid)
Grasses for sugar or syrup production - sugarcane (free trinexapac acid)
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Grasses for sugar or syrup production—sugarcane (total residues of trinexapac acid)
Oilseeds - Rape
Animal feeds
Forage - Wheat (residues of free and conjugated trinexapac acid)
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Hay and Straw - Barley and Wheat
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Rape seed forage
Fate of residues during processing
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HO
O
OH
O
O
HO
O
OHO
O
OH
OOHO OH
Barley
Wheat
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Residues in animal commodities
Estimated maximum and mean dietary burdens of farm animals
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Farm Animal Dietary Burden
Animal commodity maximum residue levels
Cattle- STMR, HR and MRLs
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Poultry - STMR, HR and MRLs
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Trinexapac and its conjugates, expressed as trinexapac acid.
Long-term intake
Short-term intake
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Changes are shown in bold. Only significant factual errors and omissions are listed.
Under Annex 1 Insert the following entries
Under Annex 1 Replace the following entries
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:azoxystrobin.
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bentazone.
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bixafen
sum of bixafen and N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1H-pyrazole-4-carboxamide (bixafen-desmethyl), expressed as bixafen
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chlorantraniliprole
Chlorpyrifos-methyl.
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: cyantraniliprole.cyantraniliprole.
sum of cyantraniliprole and 2-[3-Bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazol-5-yl]-3,4-dihydro-3,8-dimethyl-4-oxo-6-quinazolinecarbonitrile.
: sum of:-cyantraniliprole2-[3-Bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazol-5-yl]-3,4-dihydro-3,8-dimethyl-4-oxo-6-quinazolinecarbonitrile2-[3-Bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazol-5-yl]-1,4-dihydro-8-methyl-4-oxo-6-quinazolinecarbonitrile3-Bromo-1-(3-chloro-2-pyridinyl)-N-[4-cyano-2-(hydroxymethyl)-6-[(methylamino)carbonyl]phenyl]-1H-pyrazole-5-carboxamide3-Bromo-1-(3-chloro-2-pyridinyl)-N-[4-cyano-2[[(hydroxymethyl)amino]carbonyl]-6-methylphenyl]-1H-pyrazole-5-carboxamide expressed as cyantraniliprole
: cyproconazole.
cyproconazole.cyproconazole, free and conjugated.
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cyprodinil.
Dicamba
Sum of dicamba and 5-OH dicamba expressed as dicamba
Sum of dicamba and DCSA expressed as dicamba
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0.088 0.029
0.22 0.08 0.031 0.01 0.094
difenoconazole
sum of difenoconazole and 1-[2-chloro-4-(4-chloro-phenoxy)-phenyl]-2-(1,2,4-triazol)-1-yl-ethanol), expressed as difenoconazole
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Diquat
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Dithianon.
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fenbuconazole
fenpyroximate.
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fludioxonil
fludioxonil and its benzopyrrole metabolites, determined as 2,2-difluoro-1,3-benzodioxole-4-carboxylic acid and expressed as fludioxonil.
flutolanil.
flutolanil and transformation products containing the 2-trifluoromethylbenzoic acid moiety, expressed as flutolanil.
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for soya bean, maize and rape: sum of glyphosate and N-acetylglyphosate, expressed as glyphosatefor other crops: glyphosate.
sum of glyphosate and N-acetylglyphosate, expressed as glyphosate
glyphosate, N-acetylglyphosate, AMPA and N-acetyl AMPA, expressed as glyphosate
Imazapic
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Imazapyr
sum of indoxacarb and its R enantiomer.
sum of isoxaflutole and isoxaflutole diketonitrile, expressed as isoxaflutole.
sum of isoxaflutole and isoxaflutole diketonitrile, expressed as isoxaflutole.
sum of isoxaflutole, isoxaflutole diketonitrile, RPA
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205834 (2-aminomethylene-l-cyclopropyl-3-(2-mesyl-4-trifluoromethylphenyl)-propane-1,3-dione) and RPA 207048 (1-cyclopropyl-2-hydroxymethylene-3-(2-mesyl-4-trifluoromethylphenyl)-propane-1,3-dione), including their conjugates, expressed as isoxaflutole.
malathion
:mandipropamid.
penthiopyrad
sum of penthiopyrad and 1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide (PAM), expressed as penthiopyrad
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propiconazolepropiconazole plus all metabolites
convertible to 2.4-dichlorobenzoic acid, expressed as Propiconazole
pyrimethanil
Spirotetramat and its enol metabolite, 3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]dec-3-en-2-one, expressed as spirotetramat
Spirotetramat, enol metabolite 3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]dec-3-en-2-one, ketohydroxy metabolite 3-(2,5-dimethylphenyl)-3-hydroxy-8-methyoxy-1-azaspiro[4.5]decane-2,4-dione, monohydroxy metabolite cis-3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one, and enol glucoside metabolite glucoside of 3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]dec-3-en-2-one, expressed as spirotetramat.
Spirotetramat enol metabolite, 3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]dec-3-en-2-one, expressed as spirotetramat
sulfoxaflor.
tolfenpyrad.PT-
CA and OH-PT-CA) expressed as tolfenpyradsum of tolfenpyrad, and free and conjugated
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PT-CA (and OH-PT-CA) expressed as tolfenpyrad.
triazophos
Residues analysed as 4-chloro-2-(trifluoromethyl)aniline and expressed as parent triflumizole.
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Trinexapac (acid) Trinexapac and its conjugates, expressed as
trinexapac acid
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sec
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ortho
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S
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1 Horticulture: a select bibliography, 1976 (E)2 Cotton specialists and research institutions
in selected countries, 1976 (E)3 Food legumes: distribution, adaptability
and biology of yield, 1977 (E F S)4 Soybean production in the tropics, 1977
(C E F S)4 Rev.1 Soybean production in the tropics (first
revision), 1982 (E)5 Les systèmes pastoraux sahéliens, 1977 (F)6 Pest resistance to pesticides and crop loss
assessment – Vol. 1, 1977 (E F S)6/2 Pest resistance to pesticides and crop loss
assessment – Vol. 2, 1979 (E F S)6/3 Pest resistance to pesticides and crop loss
assessment – Vol. 3, 1981 (E F S)7 Rodent pest biology and control –
Bibliography 1970-74, 1977 (E)8 Tropical pasture seed production, 1979
(E F** S**)9 Food legume crops: improvement and
production, 1977 (E)10 Pesticide residues in food, 1977 – Report,
1978 (E F S)10 Rev. Pesticide residues in food 1977 – Report,
1978 (E)10 Sup. Pesticide residues in food 1977 –
Evaluations, 1978 (E)11 Pesticide residues in food 1965-78 – Index
and summary, 1978 (E F S)12 Crop calendars, 1978 (E/F/S)13 The use of FAO specifications for plant
protection products, 1979 (E F S)14 Guidelines for integrated control of rice
insect pests, 1979 (Ar C E F S)15 Pesticide residues in food 1978 – Report,
1979 (E F S)15 Sup. Pesticide residues in food 1978 –
Evaluations, 1979 (E)16 Rodenticides: analyses, specifications,
formulations, 1979 (E F S)17 Agrometeorological crop monitoring and
forecasting, 1979 (C E F S)18 Guidelines for integrated control of maize
pests, 1979 (C E)19 Elements of integrated control of sorghum
pests, 1979 (E F S)20 Pesticide residues in food 1979 – Report,
1980 (E F S)20 Sup. Pesticide residues in food 1979 –
Evaluations, 1980 (E)
FAO TECHNICAL PAPERS
FAO PLANT PRODUCTION AND PROTECTION PAPERS
21 Recommended methods for measurement of pest resistance to pesticides, 1980 (E F)
22 China: multiple cropping and related crop production technology, 1980 (E)
23 China: development of olive production, 1980 (E)
24/1 Improvement and production of maize, sorghum and millet – Vol. 1. General principles, 1980 (E F)
24/2 Improvement and production of maize, sorghum and millet – Vol. 2. Breeding, agronomy and seed production, 1980 (E F)
25 Prosopis tamarugo: fodder tree for arid zones, 1981 (E F S)
26 Pesticide residues in food 1980 – Report, 1981 (E F S)
26 Sup. Pesticide residues in food 1980 – Evaluations, 1981 (E)
27 Small-scale cash crop farming in South Asia, 1981 (E)
28 Second expert consultation on environmental criteria for registration of pesticides, 1981 (E F S)
29 Sesame: status and improvement, 1981 (E)30 Palm tissue culture, 1981 (C E)31 An eco-climatic classification of
intertropical Africa, 1981 (E)32 Weeds in tropical crops: selected abstracts,
1981 (E)32 Sup.1 Weeds in tropical crops: review of
abstracts, 1982 (E)33 Plant collecting and herbarium
development, 1981 (E)34 Improvement of nutritional quality of food
crops, 1981 (C E)35 Date production and protection, 1982
(Ar E)36 El cultivo y la utilización del tarwi –
Lupinus mutabilis Sweet, 1982 (S)37 Pesticide residues in food 1981 – Report,
1982 (E F S)38 Winged bean production in the tropics,
1982 (E)39 Seeds, 1982 (E/F/S) 40 Rodent control in agriculture, 1982
(Ar C E F S)41 Rice development and rainfed rice
production, 1982 (E)42 Pesticide residues in food 1981 –
Evaluations, 1982 (E)
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43 Manual on mushroom cultivation, 1983 (E F)
44 Improving weed management, 1984 (E F S)45 Pocket computers in agrometeorology,
1983 (E)46 Pesticide residues in food 1982 – Report,
1983 (E F S)47 The sago palm, 1983 (E F)48 Guidelines for integrated control of cotton
pests, 1983 (Ar E F S)49 Pesticide residues in food 1982 –
Evaluations, 1983 (E)50 International plant quarantine treatment
manual, 1983 (C E)51 Handbook on jute, 1983 (E)52 The palmyrah palm: potential and
perspectives, 1983 (E)53/1 Selected medicinal plants, 1983 (E)54 Manual of fumigation for insect control,
1984 (C E F S)55 Breeding for durable disease and pest
resistance, 1984 (C E)56 Pesticide residues in food 1983 – Report,
1984 (E F S)57 Coconut, tree of life, 1984 (E S)58 Economic guidelines for crop pest control,
1984 (E F S)59 Micropropagation of selected rootcrops,
palms, citrus and ornamental species, 1984 (E)
60 Minimum requirements for receiving and maintaining tissue culture propagating material, 1985 (E F S)
61 Pesticide residues in food 1983 – Evaluations, 1985 (E)
62 Pesticide residues in food 1984 – Report, 1985 (E F S)
63 Manual of pest control for food security reserve grain stocks, 1985 (C E)
64 Contribution à l’écologie des aphides africains, 1985 (F)
65 Amélioration de la culture irriguée du riz des petits fermiers, 1985 (F)
66 Sesame and safflower: status and potentials, 1985 (E)
67 Pesticide residues in food 1984 – Evaluations, 1985 (E)
68 Pesticide residus in food 1985 – Report, 1986 (E F S)
69 Breeding for horizontal resistance to wheat diseases, 1986 (E)
70 Breeding for durable resistance in perennial crops, 1986 (E)
71 Technical guideline on seed potato micropropagation and multiplication, 1986 (E)
72/1 Pesticide residues in food 1985 – Evaluations – Part I: Residues, 1986 (E)
72/2 Pesticide residues in food 1985 – Evaluations – Part II: Toxicology, 1986 (E)
73 Early agrometeorological crop yield assessment, 1986 (E F S)
74 Ecology and control of perennial weeds in Latin America, 1986 (E S)
75 Technical guidelines for field variety trials, 1993 (E F S)
76 Guidelines for seed exchange and plant introduction in tropical crops, 1986 (E)
77 Pesticide residues in food 1986 – Report, 1986 (E F S)
78 Pesticide residues in food 1986 – Evaluations – Part I: Residues, 1986 (E)
78/2 Pesticide residues in food 1986 – Evaluations – Part II: Toxicology, 1987 (E)
79 Tissue culture of selected tropical fruit plants, 1987 (E)
80 Improved weed management in the Near East, 1987 (E)
81 Weed science and weed control in Southeast Asia, 1987 (E)
82 Hybrid seed production of selected cereal, oil and vegetable crops, 1987 (E)
83 Litchi cultivation, 1989 (E S)84 Pesticide residues in food 1987 – Report,
1987 (E F S)85 Manual on the development and use of
FAO specifications for plant protection products, 1987 (E** F S)
86/1 Pesticide residues in food 1987 – Evaluations – Part I: Residues, 1988 (E)
86/2 Pesticide residues in food 1987 – Evaluations – Part II: Toxicology, 1988 (E)
87 Root and tuber crops, plantains and bananas in developing countries – challenges and opportunities, 1988 (E)
88 Jessenia and Oenocarpus: neotropical oil palms worthy of domestication, 1988 (E S)
89 Vegetable production under arid and semi-arid conditions in tropical Africa, 1988 (E F)
90 Protected cultivation in the Mediterranean climate, 1990 (E F S)
91 Pastures and cattle under coconuts, 1988 (E S)
92 Pesticide residues in food 1988 – Report, 1988 (E F S)
93/1 Pesticide residues in food 1988 – Evaluations –
Part I: Residues, 1988 (E)93/2 Pesticide residues in food 1988 –
Evaluations – Part II: Toxicology, 1989 (E)
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94 Utilization of genetic resources: suitable approaches, agronomical evaluation and use, 1989 (E)
95 Rodent pests and their control in the Near East, 1989 (E)
96 Striga – Improved management in Africa, 1989 (E)
97/1 Fodders for the Near East: alfalfa, 1989 (Ar E)
97/2 Fodders for the Near East: annual medic pastures, 1989 (Ar E F)
98 An annotated bibliography on rodent research in Latin America 1960-1985, 1989 (E)
99 Pesticide residues in food 1989 – Report, 1989 (E F S)
100 Pesticide residues in food 1989 – Evaluations – Part I: Residues, 1990 (E)
100/2 Pesticide residues in food 1989 – Evaluations – Part II: Toxicology, 1990 (E)
101 Soilless culture for horticultural crop production, 1990 (E)
102 Pesticide residues in food 1990 – Report, 1990 (E F S)
103/1 Pesticide residues in food 1990 – Evaluations – Part I: Residues, 1990 (E)
104 Major weeds of the Near East, 1991 (E)105 Fundamentos teórico-prácticos del cultivo
de tejidos vegetales, 1990 (S)106 Technical guidelines for mushroom
growing in the tropics, 1990 (E)107 Gynandropsis gynandra (L.) Briq. – a
tropical leafy vegetable – its cultivation and utilization, 1991 (E)
108 Carambola cultivation, 1993 (E S)109 Soil solarization, 1991 (E)110 Potato production and consumption in
developing countries, 1991 (E)111 Pesticide residues in food 1991 – Report,
1991 (E)112 Cocoa pest and disease management in
Southeast Asia and Australasia, 1992 (E)113/1 Pesticide residues in food 1991 –
Evaluations – Part I: Residues, 1991 (E)114 Integrated pest management for protected
vegetable cultivation in the Near East, 1992 (E)
115 Olive pests and their control in the Near East, 1992 (E)
116 Pesticide residues in food 1992 – Report, 1993 (E F S)
117 Quality declared seed, 1993 (E F S)118 Pesticide residues in food 1992 –
Evaluations – Part I: Residues, 1993 (E)119 Quarantine for seed, 1993 (E)120 Weed management for developing
countries, 1993 (E S)
120/1 Weed management for developing countries, Addendum 1, 2004 (E F S)
121 Rambutan cultivation, 1993 (E)122 Pesticide residues in food 1993 – Report,
1993 (E F S)123 Rodent pest management in eastern
Africa, 1994 (E)124 Pesticide residues in food 1993 –
Evaluations – Part I: Residues, 1994 (E)125 Plant quarantine: theory and practice,
1994 (Ar)126 Tropical root and tuber crops – Production,
perspectives and future prospects, 1994 (E)127 Pesticide residues in food 1994 – Report,
1994 (E)128 Manual on the development and use of
FAO specifications for plant protection products – Fourth edition, 1995 (E F S)
129 Mangosteen cultivation, 1995 (E)130 Post-harvest deterioration of cassava – A biotechnology perspective, 1995 (E)131/1 Pesticide residues in food 1994 –
Evaluations – Part I: Residues, Volume 1, 1995 (E)131/2 Pesticide residues in food 1994 –
Evaluations – Part I: Residues, Volume 2, 1995 (E)132 Agro-ecology, cultivation and uses of
cactus pear, 1995 (E)133 Pesticide residues in food 1995 – Report,
1996 (E)134 (Number not assigned)135 Citrus pest problems and their control in
the Near East, 1996 (E)136 El pepino dulce y su cultivo, 1996 (S)137 Pesticide residues in food 1995 –
Evaluations – Part I: Residues, 1996 (E)138 Sunn pests and their control in the Near
East, 1996 (E)139 Weed management in rice, 1996 (E)140 Pesticide residues in food 1996 – Report,
1997 (E)141 Cotton pests and their control in the Near
East, 1997 (E)142 Pesticide residues in food 1996 –
Evaluations – Part I Residues, 1997 (E)143 Management of the whitefly-virus
complex, 1997 (E)144 Plant nematode problems and their control
in the Near East region, 1997 (E)145 Pesticide residues in food 1997 – Report,
1998 (E)146 Pesticide residues in food 1997 –
Evaluations – Part I: Residues, 1998 (E)
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147 Soil solarization and integrated management of soilborne pests, 1998 (E)
148 Pesticide residues in food 1998 – Report, 1999 (E)
149 Manual on the development and use of FAO specifications for plant protection products – Fifth edition, including the new procedure, 1999 (E)
150 Restoring farmers’ seed systems in disaster situations, 1999 (E)
151 Seed policy and programmes for sub-Saharan Africa, 1999 (E F)
152/1 Pesticide residues in food 1998 – Evaluations –
Part I: Residues, Volume 1, 1999 (E)152/2 Pesticide residues in food 1998 –
Evaluations – Part I: Residues, Volume 2, 1999 (E)153 Pesticide residues in food 1999 – Report,
1999 (E)154 Greenhouses and shelter structures for
tropical regions, 1999 (E)
155 Vegetable seedling production manual, 1999 (E)
156 Date palm cultivation, 1999 (E)156 Rev.1 Date palm cultivation, 2002 (E)157 Pesticide residues in food 1999 –
Evaluations – Part I: Residues, 2000 (E)158 Ornamental plant propagation in the
tropics, 2000 (E)159 Seed policy and programmes in the Near
East and North Africa, 2000160 Seed policy and programmes for Asia and
the Pacific, 2000 (E)161 Silage making in the tropics with particular
emphasis on smallholders, 2000 (E S)162 Grassland resource assessment for pastoral
systems, 2001, (E)163 Pesticide residues in food 2000 – Report,
2001 (E)164 Seed policy and programmes in Latin
America and the Caribbean, 2001 (E S)165 Pesticide residues in food 2000 –
Evaluations – Part I, 2001 (E)166 Global report on validated alternatives
to the use of methyl bromide for soil fumigation, 2001 (E)
167 Pesticide residues in food 2001 – Report, 2001 (E)
168 Seed policy and programmes for the Central and Eastern European countries, Commonwealth of Independent States and other countries in transition, 2001 (E)
169 Cactus (Opuntia spp.) as forage, 2003 (E S)170 Submission and evaluation of pesticide
residues data for the estimation of maximum residue levels in food and feed, 2002 (E)
171 Pesticide residues in food 2001 – Evaluations –
Part I, 2002 (E)172 Pesticide residues in food, 2002 – Report,
2002 (E)173 Manual on development and use of FAO
and WHO specifications for pesticides, 2002 (E S)
174 Genotype x environment interaction – Challenges and opportunities for plant breeding and cultivar recommendations, 2002 (E)
175/1 Pesticide residues in food 2002 – Evaluations –
Part 1: Residues – Volume 1 (E)175/2 Pesticide residues in food 2002 –
Evaluations – Part 1: Residues – Volume 2 (E)176 Pesticide residues in food 2003 – Report,
2004 (E)177 Pesticide residues in food 2003 –
Evaluations – Part 1: Residues, 2004 (E)178 Pesticide residues in food 2004 – Report,
2004 (E)179 Triticale improvement and production,
2004 (E)180 Seed multiplication by resource-limited
farmers - Proceedings of the Latin American workshop, 2004 (E)
181 Towards effective and sustainable seed-relief activities, 2004 (E)
182/1 Pesticide residues in food 2004 – Evaluations – Part 1: Residues, Volume 1 (E)
182/2 Pesticide residues in food 2004 – Evaluations –
Part 1: Residues, Volume 2 (E)183 Pesticide residues in food 2005 – Report,
2005 (E)184/1 Pesticide residues in food 2005 –
Evaluations – Part 1: Residues, Volume 1 (E)184/2 Pesticide residues in food 2005 –
Evaluations – Part 1: Residues, Volume 2 (E)185 Quality declared seed system, 2006 (E F S)186 Calendario de cultivos – América Latina y el
Caribe, 2006 (S)187 Pesticide residues in food 2006 – Report,
2006 (E)
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188 Weedy rices – origin, biology, ecology and control, 2006 (E S)
189/1 Pesticide residues in food 2006 – Evaluations –
Part 1: Residues, Volume 1 (E)189/2 Pesticide residues in food 2006 –
Evaluations – Part 1: Residues, Volume 2 (E)190 Guidance for packing, shipping, holding and release of sterile flies in area-wide fruit fly control programmes, 2007 (E)191 Pesticide residues in food 2007 – Report,
2007 (E)192 Pesticide residues in food 2007 –
Evaluations – Part 1: Residues, 2008 (E)193 Pesticide residues in food 2008 – Report,
2008 (E)194 Pesticide residues in food 2008 –
Evaluations, 2008 (E)195 Quality declared planting material –
Protocols and standards for vegetatively propagated crops, 2010 (E)
196 Pesticide residues in food 2009 – Report, 2009 (E)
197 Submission and evaluation of pesticide residues
data for the estimation of maximum residue levels
in food and feed, 2009 (E)198 Pesticide residues in food 2009 –
Evaluations – Part 1: Residues, 2010 (E)199 Rearing codling moth for the sterile insect
technique, 2010 (E)200 Pesticide residues in food 2010 − Report,
2011 (E)201 Promoting the Growth and Development
of Smallholder Seed Enterprises for Food Security Crops
Case Studies from Brazil, Côte d’Ivoire and India (E) 2010
202 Seeds in Emergencies: a technical handbook (E) 2011
203 Sustainable wheat rust resistance – Learning from history
204 State of knowledge on breeding for durable resistance to soybean rust disease in the developing world
205 The FAO/IAEA Spreadsheet for Designing and Operation of Insect Mass Rearing Facilities
206 Pesticide Residues in food 2010 – Evaluations – Part 1
207 Plant breeding and seed systems for rice, vegetables, maize and pulses in Bangladesh
208 The dynamic tension between public and private plant breeding in Thailand
209 The strategic role of plant breeding in Uruguay: analysis through an agricultural innovation system framework
210 Evolving a plant breeding and seed system in sub-Saharan Africa in an era of donor dependence
211 Pesticide residues in food 2011 − Report, 2011 (E)
212 Pesticide Residues in food 2011 – Evaluations – Part 1
213 Evaluation of pesticide residues - Training Manual
214 Agricultural handtools; Guidelines for Field Officers and Procurement
215 Pesticide residues in food 2012 − Report, 2011 (E)
216 Pesticide residues in Food 2011 – Evaluations – Part 1 (E)
217 Good Agricultural Practices for greenhouse vegetable crops: Principles for Mediterranean climate areas (E)
218 Cassava Farmer Field Schools – Resource material for facilitators in sub-Saharan Africa
Availability: July 2013
Ar – Arabic Multil – MultilingualC – Chinese * Out of printE – English ** In preparationF – FrenchP – PortugueseS – Spanish
The FAO Technical Papers are available through the authorized FAO Sales Agents or directly from Sales and Marketing Group, FAO, Viale delle Terme di Caracalla, 00153 Rome, Italy.
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The annual Joint Meeting of the FAO Panel of Experts on Pesticide Residues in Food and the
Environment and the WHO Core Assessment Group on Pesticide Residues was held in Geneva,
Switzerland, from 17 to 26 September 2013. The FAO Panel of Experts had met in preparatory sessions
from 6 to 10 September. The Meeting was held in pursuance of recommendations made by
previous Meetings and accepted by the governing bodies of FAO and WHO that studies should
be undertaken jointly by experts to evaluate possible hazards to humans arising from the
occurrence of pesticide residues in foods. During the meeting the FAO Panel of Experts was
responsible for reviewing pesticide use patterns (use of good agricultural practices), data on the
chemistry and composition of the pesticides and methods of analysis for pesticide residues and
for estimating the maximum residue levels that might occur as a result of the use of the
pesticides according to good agricultural use practices. The WHO Core Assessment Group was
responsible for reviewing toxicological and related data and for estimating, where possible and
appropriate, acceptable daily intakes (ADIs) and acute reference doses (ARfDs) of the pesticides
for humans. This report contains information on ADIs, ARfDs, maximum residue levels, and
general principles for the evaluation of pesticides. The recommendations of the Joint Meeting,
including further research and information, are proposed for use by Member governments of the
respective agencies and other interested parties.
I3518E/1/11.13
ISBN 978-92-5-108043-6 ISSN 0259-2517
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