pharmaceutical packaging by metals (rcpsr)

7/23/2019 Pharmaceutical Packaging by Metals (rcpsr)

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PRESENTED BY : SHAGUFTA KHAN

B. PHARM

VIII SEMESTER

PHARMACEUTICAL PACKAGING

BY METALS


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PHARMACEUTICAL PACKAGING

Pharmaceutical packaging is the means of providing protection,

presentation, identification and information, containment, and

convenience to encourage compliance with and closures.

FDA-

Packaging is the science, art and technology of enclosing or protecting

products for distribution, storage, sale, and use.

An economical means of providing protection, presentation,

identification, information and convenience for pharmaceuticals

product from the moment of production until it is used or

administered.


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METALS

Metals used in packaging including

Tin (15%)

Aluminum (60%)

Lead (25%)

These metals are useful in the preparation of collapsibletubes.

Type of metal containersa.Collapsible tubes

b. Metal containers for tablets and capsules

c. Metal foil


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TIN

Tin:

ADVANTAGES

Tin is chemically inert of all collapsible tube metals.

It offers a good appearance and compatibility with a widerange of products.

PHARMACEUTICALS

F00D

product for which purity isan important consideration


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Aluminum

Aluminum tubes offer significant savings inproduct shipping costs because of their light weight.

They provide good appearance


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Lead

Lead has the lowest cost of all tube metals and iswidely used for nonfood products such asadhesives, inks, paints, and lubricants.

Lead should never be used alone for anythingtaken internally because of the risk of leadpoisoning.

The inner surface of the lead tubes are coatedand are used for products like fluoridetoothpaste.


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Type of metal containers:

Collapsible tubes

Metal containers for tablets and capsules

Metal foil


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COLLAPSIBLE TUBES The collapsible metal tube is an attractive

container that permits controlled amounts to bedispensed easily, with good re closure andadequate environmental protection to the product.

The risk of contamination of the portionremaining in the tube is minimal, because thetube does not "suck back.

It is light in weight and unbreakable, and it lendsitself to high-speed automatic filling operations.

The ductile metals used for collapsible tubes aretin (15%), aluminum (60%), and lead (25%)


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COLLAPSIBLE TUBES

Collapsible Tubes

Metal CollapsibleTubes

PlasticCollapsible

Tubes

Laminatedtubes


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METAL COLLAPSIBLE TUBES


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AdvantagesPermits controlled amount to be dispensed easily with

good reclosuer & provides adequate protection to theproduct.

Does not suck back

Disadvantages

Corrosion & Breakage


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METAL FOILS

Thin sheets of metals.


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Metal foils


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Containers for tablet and capsules


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Closures Emphasised On Metals

Closures-

METALS

1.Tin

2. AluminiumClosures Are Available In 5 Basic Designs

1) Screw-on Closure

2) Crimp-on Closure

3) Roll-on Closure

4) Friction Closure

5) Press-on Closure


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SCREW CAPCLOSURES

ROLL ON


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Tamper Resistant Packaging

As per FDA

It is a packaging in which there is an indication or barrier

to entry which if breached or missing, can reasonably

be expected to provide visible evidence to consumer

that tampering has occurred.


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Tamper Resistant Packagingo Film wrappers

o Blister package

o Strip package

o Bubble pack

o Shrink seal & bands

o Aerosol containers

o Bottle seals

o Tape sealso Breakable caps

o Foil, paper or plastic pouch


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FILM WRAPPERS

BLISTER PACKAGING


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STRIP PACKING

AEROSOL CONTAINERS


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Advantage of Metals

They are sturdy. They are impermeable to light, moisture,and

gas.

They are light in weight as compared to glasscontainers.

Labels can be printed directly on to their surface.


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Disadvantage of metals

They are expensive.

They may shed metal particles intopharmaceutical products.

They are not generally used forextemporaneous dispensing.

They react with certain chemicals of drug.


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THANK YOU.

pharmaceutical packaging by metals (rcpsr)

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