13/11/2014

1

azazMMazMU

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azazMMazMU

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Mixed-methods research on care processes in heart failure Communication as major drawback resulting in insufficient treatment Also vividly discussed during dissemination events

Knowledge of patients rather poor (despite HF nurses) Level of communication with patients inadequate Quite different priorities in therapy between GP’s and specialists

Transnational HF networkDevelopment of patient-centred telemedicine device Patient-education and -monitoring

13/11/2014

2

azazMMazMU

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Estimate of app. 15 millionpatients in Europe

One of the most costly diseases App. 2% of health care budget

One of the most malignant diseasesMost common reason for hospital-

ization in pts aged >65years Usually accompanied with multiple

co-morbidities 40% have ≥5 co-morbidities

0%2%4%6%8%

10%12%14%16%18%20%

40 50 60 70 80 90Age

azazMMazMU

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Standard regimen according to guidelines

Clinical inputNYHA class

LVEF, HF‐etiology

Lab results, ECG

Signs & Symptoms

Age, Co‐morbidites, 

Side‐effects

13/11/2014

3

azazMMazMU

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Patient preferencesPatient knowledge Patient capabilities

Clinical input “Sensor” input

Biomarkers (e.g. NT-proBNP, sST2)

miRNA

Enhanced treatment decision

Drug/Dose regimen A Drug/Dose regimen B Drug/Dose regimen C

Optimising individual treatment

Targeted drug use & minimizing side effects

(decreased medication for same benefit / increased medication for increased benefit)

HF-relatedSymptoms, aetiology etc.

Patient input

Co-morbiditiesrelated

Tele-medicine sensors(e.g. impedance, BP)

azazMMazMU

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Development of patient-centred, decision support system,which is based on tele-medicine device in order to Improve patient knowledge Transfer large parts of treatment to patients’ home, run by the patients Individualize care of patients Improve communication between all important stakeholders (i.e.

patient, GP, cardiologist, other specialists if applicable, heart failurenurse if applicable, paramedics as applicable)

Improve outcome of patients Reduce costs

13/11/2014

4

azazMMazMU

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Impossible to address all aspects in one project Focus on aims that realistically can be achieved

Which parts are crucial for further development andimplementation?

What innovation is required? Product innovation Service innovation Process innovation

azazMMazMU

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Improved communication between all stakeholders of care GP’s, specialists, paramedicals, and importantly patients

Improved care processes with more patient’s self-management Tele-health central (with different focus than at present) Important business opportunities

ICT infrastructure for coordinated and integrated care Collaboration academic institutes and industrial partners

Improvement in care of chronic diseases Tackling the needs of the growing elderly population

13/11/2014

5

azazMMazMU

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Taking advantage of knowledge in different countries Partners with specific expertise

Influence of different health-care systems unknown, butprobably much underestimated

Implementation in different countries not uniformBusiness models may vary in different countries