pmdt advocacy.pptx
TRANSCRIPT
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ProgrammaticManagement of Drug
ResistantTuberculosis
Region XIIICARAGA
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BACKGROUND ON
DRUGR!"I"TANTTUB!RCU#O"I"
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De%artment of &ealt' ( National TB Control Program
Rela) an* sit bac+,An* be attenti-e li+e
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Training on PMDT for &ealt'.acilit/ "ta0
BACKGROUND ONDRUGR!"I"TANTTUB!RCU#O"I"
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1'at is MDRTB$
MultiDrug Resistant TB
A TB patient who is resistant toIsonia2i* AND Rifam%icin ( 2 of the5 rst line anti-TB drugs)
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base* on*rugsusce%tibilit/ testing
•
Multi*rug ( resistant TB 4MDR (TB5 – Resistance to at least Isonia2i* AND
Rifam%icin, with or without resistance
to other anti-TB drugs.
• !)tensi-el/ *rug ( resistant TB4XDR ( TB5
– MDR ( TB with resistance to any6uoro7uinolone and to at least one ofthe three secon* ( line in8ectable*rugs (apreo!ycin, "ana!ycin, and
A!i#acin)
C f D
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Causes of Drugresistant TB
De%artment of &ealt' ( National TB Control Program
AC9UIR!DDRUG
R!"I"TANC!
PRIMAR: DRUG
R!"I"TANC!
!)%osure to*rug
susce%tible TB
Infection ;it'*rug
susce%tible TB
Acti-e
*rugsusce%tible TB
Acti-e*rugresistant
TB
.urt'er*rug
resistance
Infection ;it'*rugresistant
TB
!)%osure to*rugresistant
TB
Exposure to
anti-TB
drug/s
Exposure to
anti-TB drug/s
Two pathways leading
to
Drug-resistant TB
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Causes of DrugResistant TB
Ac7uire* Drug ( Resistant TB – selection of !utant resistant strains,
e$entually %eco!ing the do!inant strain
– Result of ina*e7uate, incom%lete, or
%oor treatment 7ualit/
1' i* MDR TB
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1'/ consi*er MDRTB a%roblem$
•
&t is di'cult to treat. uration of ?mont's using secon* line antiTB *rugs@
• &t is epensi$e. rugs and patient support
cost P> ( P>.
• *ndetected + wrongly treated R-TB willlead to
- continuous trans!ission
- tensi$ely rug Resistant TB (/R TB)
- death
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Pre-entDrugResistant TB
0. arly detection and high 1uality
treat!ent of drug-suscepti%le TB.2. arly detection and high 1uality
treat!ent of drug-resistant TB.
. 3ecti$e i!ple!entation of infectioncontrol !easures.
4. trengthening and regulation of health
syste!s.5. Addressing underlying ris# factors and
social deter!inants.
> &i ' MDR TB
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> &ig' MDRTBBur*en Countries
t' a!ong the 26 7igh
Burden ountries in ter!sof RTB esti!ates
879 :lo%al Report 2;04
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Casest'at &a-e MDR ( TB in > TB
Burdenountries
4.;< 22<
=hilippines >@F >
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>
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>
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C!N"U"
C!N"U" O. !NRO##!D MDRTBPATI!NT" in CARAGA R!GION
(starting fro! 2;00 up to thepresent)
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C!N"U"
PMDT CARAGA
C!N"U" O. !NRO##!DJ>
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C!N"U"
;
5
0;
05
2;
25
;
5
4;
45
2;
6
42
@
!nrolle*
.nrolled
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ProgrammaticManagement of
Drugresistant TB4PMDT5
Management of
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Management of Drugresistant TB4PMDT5
•
A collecti$e strategy using thedi3erent co!ponents of the national
TB control progra! to e3ecti$ely!anage drug-resistant tu%erculosis.
• &t include acti$ities on case*etection treatmentsur-eillance monitoring an*e-aluation of t'e %rogramLs%erformance@
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ID!NTI.ICATION O.
PR!"UMPTI! DRTB an* D9uali3e* for GX Testing
Case .in*ing for PMDT
De%artment of &ealt' ( National TB Control Program
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Bacteriologically
Confirmed RR-TB
Referring
Unit
PMDT.acilit/
I*enti3cation an*
referral ofPresum%ti-e DR TB "creeningassessment
s%utumcollection
Case .in*ing "trateg/ for
PMDT
Xpert
TB/R!"
Test
Rifam%icin
resistant
#ung Center of t'e P'ili%%ines National Center for Pulmonar/
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Test
• Roll-9ut and *se of TB+Rif :ene/pert as %rimar/
*iagnostic tool for MDRTB
• &!pro$ing Turnaround Ti!es fro! 4-5 !onths for diagnosis ofRTB to > 'ours for *iagnosis of Rifam%icin Resistance
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=resu!pti$e rug-suscepti%le TB
(-TB) satisfying at least one of thefollowingC• ?ew cases who are negati$e
%ut with chest /-ray ndingssuggesti$e of TB.
• ?ew cases who are hildren with
presu!pti$e TB.• ?ew cases who are =resu!pti$e
etra-pul!onary TB.
D"TB
De%artment of &ealt' ( National TB Control Program
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• =resu!pti$e TB (whether adult,
adolescent or child) who %elongs to anyof the RTB high-ris# groups, such asC
–Retreat!ent cases
–?ew TB cases that are contacts ofconr!ed R-TB cases
–?ew TB cases that are non-con$erter
of ategory 0 –=eople li$ing with 7&D with signs and
sy!pto!s of TB
DRTB
De%artment of &ealt' ( National TB Control Program
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PMDT Referrals
Nee*e* Re7uirements
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Nee*e* Re7uirementsfor PMDT Referral
o!pletely lled ?T= Referral Eor! =hotocopy of ?T= Record result ( should not %e !ore than 0 !onthold)
/R reading ( w+ in !os.) /R l!Refer toCARAGA Regional &os%ital ( Treatment Center
"atellite Treatment CenterA*ela "erra T/ Memorial Me*ical CenterButuan Me*ical CenterBislig District &os%ital
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Referrals
creening and Testing is ERFFF Ga%oratory a!ination is ERFFF edicines for the whole course of
treat!ent is ERFFF 8ith =atient na%ler (allowance)
R!GION XIII PMDT
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R!GION XIII PMDT.acilities
Agusan *elNorte
Pro-incial&os%ital (
AgusanNorte
E?
"iargaoDistrict&os%ital
"iargaoIslan*s
"DN
aragRegional7ospital >
urigao ity=>>EEH
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Partners
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Hoin us in the Eight againstRTBF