pmdt advocacy.pptx

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    ProgrammaticManagement of Drug

    ResistantTuberculosis

    Region XIIICARAGA

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    BACKGROUND ON

    DRUGR!"I"TANTTUB!RCU#O"I"

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    De%artment of &ealt' ( National TB Control Program

    Rela) an* sit bac+,An* be attenti-e li+e

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    Training on PMDT for &ealt'.acilit/ "ta0 

    BACKGROUND ONDRUGR!"I"TANTTUB!RCU#O"I"

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    1'at is MDRTB$

    MultiDrug Resistant TB

    A TB patient who is resistant toIsonia2i* AND Rifam%icin ( 2 of the5 rst line anti-TB drugs)

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     base* on*rugsusce%tibilit/ testing

    Multi*rug ( resistant TB 4MDR (TB5 – Resistance to at least Isonia2i* AND

    Rifam%icin, with or without resistance

    to other anti-TB drugs.

    • !)tensi-el/ *rug ( resistant TB4XDR ( TB5

     – MDR ( TB  with resistance to any6uoro7uinolone and to at least one ofthe three secon* ( line in8ectable*rugs (apreo!ycin, "ana!ycin, and

    A!i#acin)

    C f D

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    Causes of Drugresistant TB

    De%artment of &ealt' ( National TB Control Program

    AC9UIR!DDRUG

    R!"I"TANC!

    PRIMAR: DRUG

    R!"I"TANC!

    !)%osure to*rug

    susce%tible TB

    Infection ;it'*rug

    susce%tible TB

    Acti-e

    *rugsusce%tible TB

    Acti-e*rugresistant

    TB

    .urt'er*rug

    resistance

    Infection ;it'*rugresistant

    TB

    !)%osure to*rugresistant

    TB

    Exposure to

    anti-TB

    drug/s

    Exposure to

    anti-TB drug/s

    Two pathways leading

    to

    Drug-resistant TB

    C f D

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    Causes of DrugResistant TB

    Ac7uire* Drug ( Resistant TB – selection of !utant resistant strains,

    e$entually %eco!ing the do!inant strain

     – Result of ina*e7uate, incom%lete, or

    %oor treatment 7ualit/

    1' i* MDR TB

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    1'/ consi*er MDRTB a%roblem$

    &t is di'cult to treat. uration of ?mont's using secon* line antiTB *rugs@

    • &t is epensi$e. rugs and patient support

    cost P> ( P>.

    • *ndetected + wrongly treated R-TB willlead to

    - continuous trans!ission

    - tensi$ely rug Resistant TB (/R TB)

    - death

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     Pre-entDrugResistant TB

    0. arly detection and high 1uality

    treat!ent of drug-suscepti%le TB.2. arly detection and high 1uality

    treat!ent of drug-resistant TB.

    . 3ecti$e i!ple!entation of infectioncontrol !easures.

    4. trengthening and regulation of health

    syste!s.5. Addressing underlying ris# factors and

    social deter!inants.

    > &i ' MDR TB

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    > &ig' MDRTBBur*en Countries

    t' a!ong the 26 7igh

    Burden ountries in ter!sof RTB esti!ates

    879 :lo%al Report 2;04

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     Casest'at &a-e MDR ( TB in > TB

    Burdenountries

    4.;< 22<

    =hilippines >@F >

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    >

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    >

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    C!N"U"

    C!N"U" O. !NRO##!D MDRTBPATI!NT" in CARAGA R!GION

    (starting fro! 2;00 up to thepresent)

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    C!N"U"

    PMDT CARAGA

    C!N"U" O. !NRO##!DJ>

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    C!N"U"

    ;

    5

    0;

    05

    2;

    25

    ;

    5

    4;

    45

    2;

    6

    42

    @

    !nrolle*

    .nrolled

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    ProgrammaticManagement of 

    Drugresistant TB4PMDT5

    Management of

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    Management of Drugresistant TB4PMDT5

    A collecti$e strategy using thedi3erent co!ponents of the national

     TB control progra! to e3ecti$ely!anage drug-resistant tu%erculosis.

    • &t include acti$ities on case*etection treatmentsur-eillance monitoring an*e-aluation of t'e %rogramLs%erformance@

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    ID!NTI.ICATION O.

    PR!"UMPTI! DRTB an* D9uali3e* for GX Testing

    Case .in*ing for PMDT

    De%artment of &ealt' ( National TB Control Program

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    Bacteriologically

    Confirmed RR-TB

    Referring

    Unit

    PMDT.acilit/

    I*enti3cation an*

    referral ofPresum%ti-e DR TB "creeningassessment

    s%utumcollection

    Case .in*ing "trateg/ for

    PMDT

    Xpert

    TB/R!"

    Test

    Rifam%icin

    resistant

    #ung Center of t'e P'ili%%ines National Center for Pulmonar/

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     Test

    • Roll-9ut and *se of TB+Rif :ene/pert as %rimar/

    *iagnostic tool for MDRTB

    • &!pro$ing Turnaround Ti!es fro! 4-5 !onths for diagnosis ofRTB to > 'ours for *iagnosis of Rifam%icin Resistance

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      =resu!pti$e rug-suscepti%le TB

    (-TB) satisfying at least one of thefollowingC• ?ew cases who are negati$e

    %ut with chest /-ray ndingssuggesti$e of TB.

    •  ?ew cases who are hildren with

    presu!pti$e TB.• ?ew cases who are =resu!pti$e

    etra-pul!onary TB.

     D"TB

    De%artment of &ealt' ( National TB Control Program

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    • =resu!pti$e TB (whether adult,

    adolescent or child) who %elongs to anyof the RTB high-ris# groups, such asC

     –Retreat!ent cases

     –?ew TB cases that are contacts ofconr!ed R-TB cases

     –?ew TB cases that are non-con$erter

    of ategory 0 –=eople li$ing with 7&D with signs and

    sy!pto!s of TB

     DRTB

    De%artment of &ealt' ( National TB Control Program

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    PMDT Referrals

    Nee*e* Re7uirements

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    Nee*e* Re7uirementsfor PMDT Referral

     o!pletely lled ?T= Referral Eor! =hotocopy of ?T= Record  result ( should not %e !ore than 0 !onthold)

     /R reading ( w+ in !os.) /R l!Refer toCARAGA Regional &os%ital ( Treatment Center

    "atellite Treatment CenterA*ela "erra T/ Memorial Me*ical CenterButuan Me*ical CenterBislig District &os%ital

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    Referrals

     creening and Testing is ERFFF Ga%oratory a!ination is ERFFF edicines for the whole course of

    treat!ent is ERFFF 8ith =atient na%ler (allowance)

    R!GION XIII PMDT

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    R!GION XIII PMDT.acilities

    Agusan *elNorte

    Pro-incial&os%ital (

    AgusanNorte

    E?

    "iargaoDistrict&os%ital

    "iargaoIslan*s

    "DN

    aragRegional7ospital >

    urigao ity=>>EEH

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    Partners

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     Hoin us in the Eight againstRTBF