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16 th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems POSTER PRESENTATIONS All even numbered posters will be presented on Sunday and Monday All odd numbered posters will be presented on Tuesday and Wednesday Cellular Proteomics Drug & Biopharmaceutical Proteomics Methods, Systems & Bioinformatics Disease & Clinical Proteomics Precision & Personalised Proteomics Human Proteome Project POSTERS Cellular Proteomics A-001 Cell surface antigen-antibody microarray as a tool for detection macrophages polarization Mohamed Saiel Saeed Alhamdani, Dkfz, Germany A-002 The novel role of ADAM17 cytoplasmic domain in modulating redox state via Thioredoxin-1 Rute Alves Pereira E Costa, Brazilian Bioscience National Laboratory, Brazil A-003 Thermal proteome profiling for drug discovery Isabelle Becher, EMBL, Germany A-004 Role of lipolysis in cancer Ruth Birner-Gruenberger, Medical University Graz, Austria A-005 Genetic wiring maps of single protein states reveal on off-switch for GPCR signaling Onno Bleijerveld, The Netherlands Cancer Institute, Netherlands A-006 Natural Polysaccharide Peptide (PSP) promotes an IFN and TLR4 induced anti-HIV response in human monocytes Nawal Boukli, Universidad central del caribe, United States A-007 Understanding GSK3β function in cancer cells through precision knockout coupled to high resolution LC-MS/MS Emily Bowler, University Of Southampton, United Kingdom A-008 Proteome analysis of alveolar epithelial type II cells in response to pulmonary aspergillus fumigatus Infection Thilo Bracht, Ruhr-Universität Bochum, Germany A-009 Characterization of Data-Independent Acquisition (DIA) capabilities of a Q-TOF instrument for complex proteomics samples Peter Brechlin, Bruker Daltonik Gmbh, Germany A-010 Global profiling of dehydration-induced mitochondrial dynamics and defense response in rice Niranjan Chakraborty, National Institute Of Plant Genome Research, India

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Page 1: POSTER PRESENTATIONS - HUPO 2017hupo2017.ie/wp-content/uploads/2017/05/HUPO2017_Programme_P… · Genome Research, India. 16 P O I P S A-011 ... POSTER PRESENTATIONS POSTERS. 16 P

16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

POSTER PRESENTATIONS

All even numbered posters will be presented on Sunday and MondayAll odd numbered posters will be presented on Tuesday and Wednesday

Cellular Proteomics

Drug & Biopharmaceutical Proteomics

Methods, Systems & Bioinformatics

Disease & Clinical Proteomics

Precision & Personalised Proteomics

Human Proteome Project

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Cellular Proteomics

A-001Cell surface antigen-antibody microarray as a tool for detection macrophages polarizationMohamed Saiel Saeed Alhamdani, Dkfz, GermanyA-002The novel role of ADAM17 cytoplasmic domain in modulating redox state via Thioredoxin-1Rute Alves Pereira E Costa, Brazilian Bioscience National Laboratory, BrazilA-003Thermal proteome profiling for drug discoveryIsabelle Becher, EMBL, GermanyA-004Role of lipolysis in cancerRuth Birner-Gruenberger, Medical University Graz, AustriaA-005Genetic wiring maps of single protein states reveal on off-switch for GPCR signalingOnno Bleijerveld, The Netherlands Cancer Institute, Netherlands

A-006Natural Polysaccharide Peptide (PSP) promotes an IFN and TLR4 induced anti-HIV response in human monocytesNawal Boukli, Universidad central del caribe, United StatesA-007Understanding GSK3β function in cancer cells through precision knockout coupled to high resolution LC-MS/MSEmily Bowler, University Of Southampton, United KingdomA-008Proteome analysis of alveolar epithelial type II cells in response to pulmonary aspergillus fumigatus InfectionThilo Bracht, Ruhr-Universität Bochum, GermanyA-009Characterization of Data-Independent Acquisition (DIA) capabilities of a Q-TOF instrument for complex proteomics samplesPeter Brechlin, Bruker Daltonik Gmbh, GermanyA-010Global profiling of dehydration-induced mitochondrial dynamics and defense response in riceNiranjan Chakraborty, National Institute Of Plant Genome Research, India

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

A-011Proteomic analysis of Neutrophil Extracellular Traps (NETs) produced in response to PMA and A23187Elinor Chapman, University Of Liverpool, United KingdomA-012Retinoic acid induced specific changes in the Phosphoproteome of C17.2 Neural Stem CellsPing Chen, Hunan Normal University, ChinaA-013Proteomics approach reveals the roles of mitochondria in NLRP3 inflammasome activation in Nasopharyngeal CarcinomaI-Che Chung, Chang Gung University, TaiwanA-014Extracellular signaling in neuroblastoma through exosomes for novel drug targets discoveryVictor Corasolla Carregari, Fondazione Santa Lucia, ItáliaA-015Phosphoproteomic analysis of the neural progenitor to oligodendrocyte progenitor cell differentiationAlireza Dehghani, University Of Bonn, GermanyA-016A quantitative comparative proteomic approach to investigate Hülle cells from the filamentous fungus Aspergillus nidulansBenedict Dirnberger, University Of Goettingen, GermanyA-017Comparison of protocols for the processing of proteomics samples that are limited in quantityUte Distler, Institute for Immunology, UMC Mainz, GermanyA-018Optimisation of sensitive and robust methods for characterisation of the PLK4-regulated phosphoproteomeSamantha Ferries, University Of Liverpool, United KingdomA-019Regulation of peroxisomal matrix protein import by peroxin phosphorylationSven Fischer, Universität Freiburg, Germany

A-020Proteome remodelling in senescent peritubular cells of human testisFlorian Flenkenthaler, LAFUGA, Gene Center, LMU Munich, GermanyA-021Proteomic and phosphoproteomic analysis of cells lacking the catalytic activity of protein kinase CK2Cinzia Franchin, University Of Padova, ItalyA-022Impact of sulfation on SDF-1/receptor’s extracellular domain interaction by affinity electrophoresis and mass spectrometryMaud Fumex, Université-d’evry-val-d’essonne, FranceA-023Characterization of the signal transduction networks underlying the immunomodulation by the microbial metabolite trimethylamine.Tariq Ganief, Pct, GermanyA-024Lyn, a novel putative drug target for osteoporosis managementShubhangi Gavali, National Institute For Research In Reproductive Health (icmr), IndiaA-025Integrative proteo-metabolomic study illustrates role of nucleus in blast disease signaling and host-specific resistanceSudip Ghosh, National Institute Of Plant Genome Research, IndiaA-026Cell wall enrichment reveals further dysregulation in response to sub-MIC rifampicin stressAlexander Giddey, University Of Cape Town, South AfricaA-027Serologic profiling of the Candida albicans cell surface-associated proteome upon dimorphic transition in invasive candidiasisConcha Gil, UCM, SpainA-028The signaling pathways of folliculin: a tumor suppressor in Birt-Hogg-Dubé syndromeIris Glykofridis, VUmc - CCA, Netherlands

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

A-029New signaling pathways altered in restrictive cardiomyopathy revealed by tandem mass tag proteomics and phosphoproteomicsAldrin Gomes, University Of California, Davis, United StatesA-030Phosphoproteomic analysis of acquired resistance to trastuzumab and dual HER2-blockade in HER2-positive breast cancer cellsPaula Gonzalez Alonso, Health Research Institute Fundacion Jimenez Diaz (IIS-FJD), SpainA-031Inactivation of endogenous tissue proteases by brief exposure to high hydrostatic pressure.Vera Gross, Pressure Biosciences, Inc, United StatesA-032Analysis of human brain N-glycans by (PGC-)LC-ESI-MS using isotopically labeled standardsClemens Grünwald-Gruber, University Of Natural Resources and Life Sciences, AustriaA-033Comprehensive proteomic description of ontogenic changes in haematopoietic stem and progenitor cellsJenny Hansson, Lund University, SwedenA-034Evolutionary plasticity of neuroplastin basigin and embigin associated complexes with calcium and monocarboxylate transportersSebastian Henrich, University of Freiburg; Physiology Departement, GermanyA-035Proteome variation related to thyroid regulation by iodideMaha Hichri, Tiro CEA UNS, FranceA-036Analyzing the mechanisms of acquired resistance to MEK inhibitors in colorectal cancer using multi-proteomics approachesAnna Jarzab, Technical University Of Munich, Germany

A-037Protein iodination in thyroid function and regulationLun Jing, TIRO, FranceA-038Cell type-specific proteogenomics in the infarcted heartInmaculada Jorge, Centro Nacional De Investigaciones Cardiovasculares (cnic), SpainA-039Label-free differential phosphoproteomic analysis of recombinant chinese hamster ovary cells reveals growth related phosphoproteome modifications.Prashant Kaushik, Dublin City University, IrelandA-040Serine palmitoyltransferase protein interaction landscape and structural characterisationVan Kelly, University Of Edinburgh, United KingdomA-041Somatic MED12 nonsense mutation escapes mRNA decay and reveals a motif required for nuclear entrySalla Keskitalo, University Of Helsinki, FinlandA-042Proteome and transcriptome analyses of phosphorylation site–specific mutants of BRG1, a chromatin remodeling componentAyuko Kimura, Yokohama City University, JapanA-043Co-exposure of silver nanoparticles and Cd2+ induce disruption of the metabolic reprogramming in HepG2 cellsFrank Kjeldsen, University Of Southern Denmark, DenmarkA-044Glycoproteomic and glycomic analysis of human induced pluripotent stem cells and stem cell-derived cardiomyocytesSarah Konze, Hannover Medical School, GermanyA-045Quantitative interactome and phosphoproteome analysis identifies novel signaling components of parkinson’s disease-associated kinase PINK1Hidetaka Kosako, Tokushima University, Japan

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

A-046Novel hypoxia-driven pro-angiogenic mechanisms unveiled by secretomics analysis of mammary CAFsFernanda Kugeratski, CRUK Beatson Institute, United KingdomA-047Mechanistic insights into Ca2+ dependent regulation of cell cycle by label-free LC-MS/MS.Anna Kwasnik, UCD, IrelandA-048Comprehensive analysis of human protein N-termini enables assessment of various protein formsCheolju Lee, Korea Institute of Science and Technology, KoreaA-049Evaluation of dimethylated arginine containing peptides by LC-MS/MS with Electron Transfer DissociationStephanie Lehman, University Of Virginia, United StatesA-050Proteome-wide identification of ADP-ribose acceptor sites in mammalian cells and mouse tissuesMario Leutert, University Of Zurich, SwitzerlandA-051Comprehensive analysis of sulfonated cysteines in human peroxiredoxin 1 by Orbitrap Mass SpectrometryHong Li, Rutgers New Jersey Medical School, United StatesA-052Functional lipidomics: palmitic acid impairs hepatocellular carcinoma development by modulating membrane fluidity and glucose metabolismLyn Lin, Fudan University, ChinaA-053Quantitative proteomics analysis of a primary bladder cell line treated with ketamineJo-chuan Liu, Chang Gung University, TaiwanA-054Impact of alternative splicing on the cellular proteome quantified by targeted proteomicsYansheng Liu, Eth Zurich, Switzerland

A-055Interactome analysis of the RLTPR protein reveals its essential role in T cellsCamoin Luc, Marseille Proteomics, FranceA-056Proteomics analysis of white blood cells in healthy humansAlexey Lyashkov, National Institute On Aging, United StatesA-057Identification of cross-linked peptides in proteins subjected to photo-oxidationMichele Mariotti, Technical University of Denmark, DenmarkA-058Proteomic analysis of the impact of metabolic status and genetic predisposition on oviduct fluid compositionKatrin Meyer, LMU Munich, GermanyA-059MRM and PRM assay development for a panel of >3,000 proteins from 20 mouse tissuesSarah Michaud, Uvic Genome Bc Proteomics Centre, CanadaA-060A draft proteome map of the Ginseng(Panax Ginseng C. A Meyer): mass spectrometry-based proteomic approachCheol Woo Min, Pusan National University, South KoreaA-061Quantitative proteomic study of macrophage proteins interacting with candida albicans using an ATP affinity enrichmentLucia Monteoliva, Complutense University of Madrid, Q2818014I, SpainA-062Complete native SILAC of prototrophic yeast for proteome-wide quantificationMarcel Morgenstern, University Of Freiburg, GermanyA-063Targeted proteomics of t helper cell transcription factors and lineage specific markersRobert Moulder, University Of Turku, Finland

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

A-064Expression and association of CDK10 with ETS2 proteins during human corneal epithelial wound healingShamim Mushtaq, Ziauddin University, PakistanA-065A comprehensive analysis of glycome profiles on formalin-fixed paraffin-embedded mouse tissue sectionsChiaki Nagai-Okatani, National Institute of Advanced Industrial Science And Technology, JapanA-066Extracellular matrix function using integrated omics dissect cell wall mediated immune dynamics in wilt diseaseKanika Narula, National Institute Of Plant Genome Research, IndiaA-067Global secretome analysis of human macrophages upon activation of innate immune responseTuula Nyman, University Of Oslo, NorwayA-068Phosphoproteomic analysis of murine synaptosome in sleep deprivationOliver Ozohanics, RCNS Hung. Acad. Sci., HungaryA-069Characterization of protein-protein interactions in the synapse by chemical cross-linking mass spectrometryIwan Parfentev, Max-Planck-Institute for Biophysical Chemistry, GermanyA-070cIAPs as regulators of FALS-associated mutant SOD1Byoung Chul, Park, KRIBB, South KoreaA-071Membrane proteome of failing heart. Combined forces of trypsin and cyanogen bromideJiri Petrak, Biocev, First Faculty of Medicine, Czech RepublicA-072Quantitative phosphoproteomic analysis reveals shared and specific targets of Arabidopsis MAPkinases MPK3, MPK4 and MPK6Delphine Pflieger, CNRS, France

A-073Radiation-induced endothelial inflammation is transferred via secretome to recipient cells in a STAT-driven processJos Philipp, Helmholtz Center Munich, GermanyA-074The impact of protein thiol redox status on foetal and adult haematopoiesisKristyna Pimkova, Lund University, SwedenA-075Quantitative proteomic analysis of the interactome of mammalian S/MAR (scaffold/matrix attachment region) elementsMonika Puchalska, Max Planck Institute of Immunobiology and Epigenetics, GermanyA-076A Lysis-free, vesiculation-based methodology to isolate high purity cell membranes for proteomics and lipidomics applicationsBini Ramachandran, National Centre For Biological Sciences (ncbs), IndiaA-077Quantitative analysis of signaling pathways using 11plex TMT reagents and comprehensive phosphopeptide enrichment strategiesJohn Rogers, Thermo Fisher Scientific, United StatesA-078Proteomics analysis of heat shock proteins in glioblastoma cell lines induced by different drugsJose Cesar Rosa, Ribeirão Preto Medical School University Of São Paulo, BrazilA-079Analysis of mitochondrial protein interactome by in-organello chemical crosslinking and mass spectrometryElena Rudashevskaya, Leibniz-Institut für Analytische Wissenschaften-ISAS-e.V., GermanyA-080Extent of growth-related and drug-induced proteome changes in cancer cellsPierre Sabatier, Karolinska Institutet, Sweden

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

A-081Triple extraction enables mass spectrometry-based proteomics and phospho-proteomics and is compatible with robust multi-omics analysisVirginia Sanchez-quiles, Curie Institute, FranceA-082Investigations of LysN cleavage capability at biotinylated lysinesPeter Schein, Institute of Biochemistry and Molecular Biology, University of Bonn, Germany

A-083Comprehensive, unbiased proteomic profiling of the cell-surface, exosomal, and secreted proteomes of senescent cellsBirgit Schilling, Buck Institute for Research on Aging, United StatesA-084Dissecting the subcellular secretory glycoproteome with SWATHBen Schulz, The University Of Queensland, AustraliaA-085Comparative, LFQ-based proteomic analysis of growth-phase dependent changes of Lactobacillus kunkeei isolates from honeybeeChristian Seeger, Uppsala University, SwedenA-086Quantitative profiling of post-translational modifications by labeling-based mass spectrometry approachesBaozhen Shan, Bioinformatics Solutions, Inc., CanadaA-087Understanding the molecular effects of antipsychotics on oligodendrocytes through phosphoproteomics and their relation with schizophreniaJuliana Silva Cassoli, University Of Campinas (unicamp), BrazilA-088Effects of myristic acid on metabolism in hepg2 cells investigated by a proteomic approachGiulia Speziali, University Of Verona, Italy

A-089Quantitative map of beta-lactone induced virulence regulationMatthias Stahl, TU München, GermanyA-090GLP-1 analogues modulate MAPKs activity but not the heat shock response in human HepG2 cellsAli Tiss, Dasman Diabetes Institute, KuwaitA-091A primary human cell line for down syndrome studiesGeorge Tsangaris, Biomedical Research Foundation Of The Academy Of Athens, GreeceA-092Proteomics analysis of skeletal muscle in healthy humanCeereena Ubaida-Mohien, National Institute On Aging, United StatesA-093Proteomic insights into cancer-related extracellular proteolysis with cathepsin KMatej Vizovišek, Jožef Stefan Institute, Slovenia A-094PhD abstract competition winner. Poster will be located by the innovation stageDynamics of the neuronal surface proteotypeMarc van Oostrum, ETH Zürich, SwitzerlandA-095Highly sensitive detection of adaptation in Staphylococcus aureus applying chemical tagging of newly synthesized proteinsUwe Volker, University Medicine Greifswald, GermanyA-096Characterization of NLRP3 inflammasome signaling pathway by proteomicsJian Wang, Beijing Proteome Research Center, Beijing Institute of Radiation Medicine, ChinaA-097Integrative organelle proteomics for deep characterization of the mitochondrial proteomeBettina Warscheid, Uni Freiburg, Germany

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

A-098Mining drug resistant targets from non-small cell lung cancer by phosphoproteomicsShao-hsing Weng, Academia Sinica, TaiwanA-099Functional determination of a single methylation site in the human proteome using CRISPR/Cas9 and MS/MSMarc Wilkins, University Of New South Wales, AustraliaA-100Secretome analysis of BSA-free cardiomyocyte differentiationHanna Wolling, Hannover Medical School, GermanyA-101Quantitative proteomics reveals temporal changes of signal pathways in BV2 microglial cell activationJongmin Woo, Seoul National University, South KoreaA-102EGFR interactome reveals multiple pathways and regulatory mechanism of drug-resistance in non-small cell lung cancerPei-Shan Wu, Acadamia Sinica, TaiwanA-103Myristoylation of human FMN2 protein causes individual localization pattern and functionKayo Yamada, University of Dundee, United KingdomA-104OST3 proteins link glycosylation and magnesium transportKent Yuen Benjamin, Yeo, School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Australia, AustraliaA-105Elucidating the secondary cell wall cellulose synthase complex stoichiometry by multiple reaction monitoringXueyang Zhang, Umea University, SwedenA-106Ageing influence central carbon metabolism in a tissue specific mannerRakesh Arya, International Center For Genetic Engineering And Biotechnology, New Delhi, India, India

A-107Matrisome landscape of head and neck squamous cell carcinoma (HNSCC) -associated fibroblastsStéphane Audebert, Marseille Protéomique - Centre De Recherche En Cancérologie De Marseille, FranceA-109Environmental enrichment increases ribosomal, microtubule and metabolic proteins in pig hippocampusAnna Bassols, Universitat Autonoma De Barcelona, SpainA-110Cardiotonic steroids reveal high interference on calcium–binding/dependent protein expression in H9c2 and Hek-293 cellsCesar Batista, Ibt-unam, MexicoA-111A dynamic picture of the ubiquitinome upon proteasome inactivation.Jeroen Demmers, Erasmus University Medical Center, NetherlandsA-113Comparative study on skeletal muscle proteins from various vertebrate and invertebrate animals by agarose 2-DEMasamichi Oishi, Kitasato University School Of Science, JapanA-114Social network architecture of human immune cells unveiled by quantitative proteomicsJan Rieckmann, Max Planck Institute of Biochemistry, GermanyA-115Investigation of cardiotoxicity in 3D human cardiac microtissue modelParveen Sharma, University Of Liverpool, United KingdomA-116Mass spectrometric analysis of complete cellular proteome via direct digestion of cellsYun Xiong, Fudan University, ChinaA-117Quantitative DUB interactomics to investigate the biology of DUBsJayaprakash Natarajan, University of Dundee, United Kingdom

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

Drug & Biopharmaceutical Proteomics

B-001Phosphoproteomics of non-small-cell lung cancer cells treated with erlotinib reveals drug-resistant signatures and potential targetsJun Adachi, National Institutes Of Biomedical Innovation, Health And Nutrition, JapanB-002Optimization of biotin enrichment protocols for the analysis of biotinylated proteins by LC-MS/MSShiva Ahmadi, University Of Bonn, GermanyB-003Quantitative proteomic analysis of drug transporters in human blood brain barrierZubida Al-majdoub, The University Of Manchester, United KingdomB-004Advanced data-acquisition methods for intact protein analyses by 21 Tesla FT-ICR mass spectrometryLissa Anderson, NHMFL-FSU, United StatesB-005Towards minute-made MS assays using surface acoustic wave nebulisation (SAWN)Alina Astefanei, University Of Amsterdam, NetherlandsB-007Next-generation positional proteomics - navigating substrate degradomes with quantitative digital terminome mapsUlrich auf dem Keller, ETH Zurich, SwitzerlandB-008Identifying allergenic peptides presented class I major histocompatibility complex molecules on keratinocytesAlistair Bailey, University Of Southampton, United KingdomB-009Application of high-throughput serum proteomic strategy using DIA-MSRyotaro Ban, Yokohama City University, Japan

B-010Parallel accumulation – serial fragmentation (PASEF) on a trapped ion mobility spectrometry QTOF instrumentScarlet Beck, Bruker Daltonik GmbH, GermanyB-011In-cell structural analysis of MeCP2 – a structural basis for (P225R) Rett syndrome?Adam Belsom, The University of Edinburgh, United KingdomB-012Deployment of DOSCAT technology to quantify proteins involved in paediatric pneumococcal meningitis pathogenesisRichard Bennett, University Of Liverpool, United KingdomB-013Robust high throughput dia plasma proteomics pipeline finds body mass index-associated increases in inflammatory pathwaysTue Bjerg Bennike, Harvard Medical School, DenmarkB-014Multiplexed quantitative analysis using NeuCode SILAC metabolic labeling of signaling protein targetsRyan Bomgarden, Thermo Fisher Scientific, United StatesB-015Biopharmaceutical characterization using size exclusion and cation exchange chromatography and high resolution native mass spectrometryJonathan Bones, National Institute For Bioprocessing Research And Training, IrelandB-016A novel FAIMS interface extend the sensitivity and depth of proteomic analysesEric Bonneil, IRIC-Université de Montréal, CanadaB-017Novel capillary-flow LC-MS platform for robust proteomics profiling of cell lysates and bio-fluidsAlexander Boychenko, Thermo Fisher Scientific, Germany

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

B-018Uptake and distribution of the antidiabetic drug metformin into the perfused rat liver by MALDI-imagingGiulio Calza, University Of Helsinki, FinlandB-019HLA ligandomics drives the identification of targets for immunotherapeutics based on soluble T-cell receptorsFloriana Capuano, Immunocore Ltd, United KingdomB-020Fast phosphoproteomics analysis of human jurkat T cells by HIFU-TiO2-SCX-LC-MS/MSMónica Carrera, Spanish National Research Council (csic), SpainB-021Monitoring protein refolding process by disulfide linkage analysis of the intermediates using mass spectrometrySung-fang Chen, National Taiwan Normal University, TaiwanB-022Decoding site-specific alteration of Sialo-glycoproteome in EGFR-subtype of non-small cell lung cancer towards precision medicineYi-Ju Chen, Academia Sinica, TaiwanB-023Combined top-down and bottom-up proteomics using capillary electrophoresis–mass spectrometryChien-hsun Chen, Thermo Fisher Scientific, United StatesB-024A new database search scoring method for better identification performance of endogenous small peptidesYet-Ran Chen, Academia Sinica, TaiwanB-025Proteomic toolbox for understanding the interaction between nanodrugs and biomoleculesSusana Cristobal, Linkoping University, Sweden

B-026Universal solid-phase protein preparation (USP3) for bottom-up and top-down proteomicsLaura Dagley, The Walter and Eliza Hall Institute of Medical Research, AustraliaB-027SWATH® acquisition - a unique approach for untargeted metabolomics applicationsZuzana Demianova, Sciex, GermanyB-028Robust, multiplexed ImmunoMRM assay for relative quantitation of phosphopeptides in DNA Damage Response (DDR) pathwayJoerg Dojahn, Sciex, GermanyB-029Validation of antibodies using orthogonal methodsFredrik Edfors, KTH, SwedenB-030Analysis of a super-sensitive in vitro diagnostic platform for Troponin I, a cardiovascular biomarkerRachael Eineman, Stoller Biomarker Discovery Centre, United KingdomB-031READYBEADS: A new tool to improve robustness and reliability in LC-MS analysesQuentin Enjalbert, Anaquant, FranceB-032Cross-linking mass spectrometry database searches: perspectives and strategies for validation and error assessmentMichael Ewing, ETH Zürich, SwitzerlandB-033Fate of antigens encoded by self-amplifying RNA vaccinesLucia Eleonora Fontana, Gsk Vaccines, ItalyB-034All-inclusive proteoform profiling of serum proteins by hybrid mass spectrometry approachesVojtech Franc, Utrecht University, NetherlandsB-035A dry method for preserving tear proteinsYouhe Gao, Beijing Normal University, China

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

B-036Evaluation of KRASG12C cysteine-reactive inhibitors by proteomic cysteine profiling in living cellsViolette Gautier, Evotec, FranceB-037An organoruthenium anticancer agent shows unexpected target selectivity for plectinChristopher Gerner, University Of Vienna, Faculty of Chemistry, AustriaB-038Comparison of MALDI imaging sample preparation/DESI imaging for multimodal MSI of Pre-clinical breast cancerLee Gethings, Waters, United KingdomB-039microDIA acquisition and software enables identification of peptides in pseudo-SRM MS/MS spectra from sequence databasesMichael Heaven, Vulcan Analytical, LLC, United StatesB-040Data independent versus data dependent acquisition mass spectrometry for proteomic classification of colorectal cancer subtypesAlex Henneman, Netherlands Cancer Institute, NetherlandsB-041The winning trio in Metaproteomic: 75 cm column, Orbitrap Fusion™ Lumos™ Tribrid™ and X !TandemPipelineCeline Henry, Inra, FranceB-042Complex-centric proteome profiling by SEC-SWATH-MS reveals modularity and dynamics of the cellular proteomeMoritz Heusel, 1985, SwitzerlandB-043Optimization of SONAR collision energy ramps for different molecule classesDavid Heywood, Waters, United KingdomB-044Single amino acid resolution of glycosites using top-down UVPD of glycoproteinsJenny Ho, ThermoFisher Scientific, United Kingdom

B-045iST: a reproducible and universal sample preparation method for in-depth proteome discovery and interaction proteomicsFabian Hosp, PreOmics GmbH, GermanyB-046MRM mass spectrometry for quantification of histone H3 variants PTM marks in Arabidopsis ThalianaYajun Hu, Institutes of biomedical sciences,Fudan University, ChinaB-047A TiO2 based simultaneous multiple PTMomics enrichment strategyHonggang Huang, Arla Foods Ingredients Group P/S, DenmarkB-048Precise structural characterization of unsaturated lipids by 213 nm UV-Photodissociation MSnRomain Huguet, Thermo Fisher Scientifc, United StatesB-049Streamlined and sensitive sample preparation for phosphoproteomics using the EasyPhos workflowSean Humphrey, The University of Sydney, AustraliaB-050Assessing the selectivity of antibodies against various amyloid-beta species by an automated capillary based immunoassayMelanie Hüttenrauch, University Medical Center Göttingen (UMG), GermanyB-051Tracking subcellular localisation changes with Dynamic Organellar Maps using SILAC, TMT or LFQDaniel Itzhak, Max Planck Institute Of Biochemistry, GermanyB-052Addressing the challenges of quantitative myelin proteomicsOlaf Jahn, Max-Planck-Institute of Experimental Medicine, Germany

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

B-053A fast and sensitive LC-MS method for quantitation of a novel prodrug against Wilson’s diseaseMichel Jaquinod, CEA-Grenoble, FranceB-054Automated high-throughput sample preparation protocols for LC-MS/MS analysis of glyco-omicsJongho Jeon, College Of Pharmacy, Gachon University, South KoreaB-055EPIQ (Epic Protein Integrative Quantification): ultra-sensitive n-plexed isotopic labeling-based quantification by a model-based reconstruction methodKyowon Jeong, Seoul National University, South KoreaB-056Development of site-specific glycome analysis method of complex glycoproteomeHiroyuki Kaji, National Institute Of Advanced Industrial Science & Technology, JapanB-057Nobel protein interaction analysis method: MIK-MS (Molecular Interaction and Kinetics Mass Spectrometry)Takeshi Kawamura, The University of Tokyo, JapanB-058A novel approach for tracing 15N tracer in proteinsJasmeet Kaur Khanijou, National University Of Singapore, SingaporeB-059Protein target identification of label-free bioactive small moleculeTae Young Kim, Chemical Genomics Global Research Laboratory, Department of Biotechnology, Yonsei University, South KoreaB-060Novel-platform for discovery of an angiogenesis inhibitor and identification of target on tissues using-MALDI-MSI analysisYonghyo Kim, Chemical Genomics Global Research Laboratory, Department of Biotechnology, Yonsei University, South Korea

B-061Swedish national infrastructure for biological and medical mass spectrometrySven Kjellstrom, Lund University, SwedenB-062A multiplexed LC-MS/MS based assay for quantification of biomarkers of neurodegeneration in mouse brain homogenatesApoorva Kotian, UCB Celltech, United KingdomB-063Building ProteomeTools based on a complete synthetic human proteomeBernhard Kuster, Technical University of Munich, GermanyB-064Implementation of a novel scanning quadrupole DIA acquisition method for DESI imagingJames Langridge, Waters Corporation, United KingdomB-065Multiplexed MRM-based protein quantitation using two different stable isotope labeled isotopologues peptides for calibrationAndré LeBlanc, Mcgill University - Lady Davis Institute, CanadaB-066Development of online 2D-NCFC-RP/RPLC system for extensive and efficient proteomic analysesHangyeore Lee, Korea University, South KoreaB-067Identification of citrullinated proteins in human tissuesChien-Yun Lee, Chair of Proteomics and Bioanalytics, Technical University of Munich, GermanyB-068A core facility approach to affinity purification-data independent analysis for interactome analysisChristof Lenz, University Medical Center Goettingen, Germany

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

B-069Proteome-wide analysis of cysteine oxidation reveals metabolic sensitivity to redox stressSergio Lilla, Cruk Beatson Institute, United KingdomB-070High throughput sensitive microLC-MS/MS for peptide quantitation in highly targeted assaysErika Lin, Sciex, United StatesB-071Proteomics analysis of single cells using a carrier-assisted targeted mass spectrometry approachTao Liu, Pacific Northwest National Laboratory, United StatesB-072Zwitterionically functionalized soluble nanopolymers used for efficient glycopeptides enrichmentJialin Liu, Fudan University, ChinaB-073Application of CE-MS for the quantification of mono-phosphorylated isobaric peptidesStephen Lock, Sciex, United KingdomB-0742D-precursor selection for trapped ion mobility with parallel accumulation - serial fragmentation (TIMS-PASEF)Markus Lubeck, Bruker, GermanyB-075Top-down proteomics identifies specific post-translational O-mycoloylations, which target outer membrane proteins to the mycomembraneJulien Marcoux, Institute Of Pharmacology And Strucural Biology, FranceB-076Site-specific N-glycosylation analysis of human IgA isotypes produced in glyco-engineered plants by LC-ESI-MSDaniel Maresch, University of Natural Resources and Life Sciences, Austria

B-077Mass spectrometry characterization of DOTA-Nimotuzumab as innovative β- tracer in radio-guided surgeryClaudia Martelli, Catholic University, ItalyB-078Considerations for selecting the optimal stationary phases for proteomic trap-and-elute nanochromatographyRoy Martin, Waters, United StatesB-079Unbiased search of antibiotic targets by thermal proteome profilingAndré Mateus, European Molecular Biology Laboratory, GermanyB-080Which proteins are responsible for the selective neuronal vulnerability in Parkinson’s disease?Caroline May, Medical Proteom-Center, Ruhr-University Bochum, GermanyB-081Maximizing proteome coverage on an Orbitrap Fusion Lumos with an advanced precursor determination algorithmGraeme McAlister, Thermo Fisher Scientific, United StatesB-082Evaluation of Mitra microsampling device for multiple reaction monitoring based measurement of proteins in serumMiriam Meier, UCD Conway Institute of Biomolecular and Biomedical Research University College Dublin, IrelandB-083A new workflow for deep proteome profiling of the human spermValdemir Melechco Carvalho, Fleury Group, BrazilB-084Quantitative dot blot analysis (QDB) reveals the variation of housekeeping proteins at population levelTingting Men, Binzhou Medical University, China

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

B-085Unexpected covalent modification of protein histidine residues by drug metabolites in vitro and in vivoXiaoli Meng, University Of Liverpool, United KingdomB-086Targeted detection of peptides in complex matrices combining the MIDAS™ Workflow with the Skyline softwareDietrich Merkel, Sciex, GermanyB-087Quantitative dot blot analysis (QDB), a versatile high throughput immunoblot method for validating proteomics resultsJia Mi, Binzhou Medical University, ChinaB-088Novel highly sensitive, selective and reproducible method for quantitative analysis of redox cysteine modificationsRuzanna Mnatsakanyan, ISAS, GermanyB-089Implementation of 213 nm Ultra Violet Photo Dissociation (UVPD) on a modified Orbitrap Fusion LumosChristopher Mullen, Thermo Fisher Scientific, United StatesB-090Optimization of phase transfer surfactant-aided in-solution digestion method for an automated large-scale sample preparation systemRyohei Narumi, National Institutes Of Biomedical Innovation, Health And Nutrition, JapanB-091Proteome analysis of exhaled breath condensate before and after space flightEvgeny Nikolaev, Skoltech, Russian FederationB-092Molecular Imprinted Polymers (MIPs) for the detection of low abundance proteins as biomarkers for NSCLCRachel Norman, University Of Leicester, United Kingdom

B-093Structural proteomics uncovers the dymanic of DNA response element-transcription factor interactionPetr Novak, Institute of Microbiology, Czech RepublicB-094Highly sensitive quantitative phosphoproteomics and primary-sequence-based scoring reveals putative substrates of ERKKosuke Ogata, Graduate School of Pharmaceutical Sciences Kyoto University, JapanB-095Effect of intestinal flora on drugs, glucose and lipid metabolism in mouseSumio Ohtsuki, Kumamoto University, JapanB-096BioUb strategy: a key tool to study protein ubiquitination applied to investigate the Angelman SydromeNerea Osinalde, University Of The Basque Country (upv/ehu), SpainB-097Characterization of site-specific N-glycoproteins in DBS sample by LC-MS/MS with minimal sample preparationGun Wook Park, Korea Basic Science Institute, KoreaB-098Screening of Mycobacterium tuberculosis 19kDa antigen proteoforms by top-down and bottom-up approachesJulien Parra, CNRS IPBS, FranceB-099Capillary Electrophoresis – mass spectrometry for intact mass analysis of antibodies and antibody-drug-conjugatesAran Paulus, Thermo Scientific, United StatesB-100On-line immunoaffinity capillary electrophoresis-mass spectrometry using magnetic beads for protein biomarker analysis. Transthyretin in FAP-IRoger Peró-Gascón, University of Barcelona (UB), Spain

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

B-101Rapid, rugged, and reliable screening methods for serum peptide degradomics profilingScott Peterman, Thermo Fisher Scientific, United StatesB-102Chemical and phosphoproteomics for mechanism of action analysis of AKT inhibitors in breast cancerSvenja Petzoldt, Technical University of Munich, GermanyB-103The loss-less and nano-flow SPIDER fractionator for high sensitivity, high coverage proteomicsGarwin Pichler, PreOmics GmbH,, GermanyB-104Comparison and optimization of global pSTY and pY-specific enrichment methods for mass spectrometry-based phosphoproteomicsSander Piersma, Oncoproteomics Laboratory, VU University Medical Center, NetherlandsB-105A mass spectrometry approach for the identification and localization of lysozyme modifications by acroleinAndrew Pitt, Aston University, United KingdomB-106Optimisation of methodologies for the in-solution preparation of human synovial fluid prior to SWATH-MS analysis.Rachel Reed, Manchester University, United KingdomB-107Prioritized iRT in spectral libraries generated from multiple sources for the targeted analysis of DIALukas Reiter, Biognosys AG, SwitzerlandB-108An in vitro MS assay for sensitive determination of donor specific MHC class II immunopeptidomesRicardo Resende, Abzena, United KingdomB-109Increased efficiency for the preparation of complex proteomic samplesMichael Rosenblatt, Promega, United States

B-110Development of reference protein extraction protocols to quantify biotherapeutics in mice tissues by UPLC-sMRMBlandine Rougemont, Ucb, United KingdomB-111Glycopeptide analysis to examine the role of chlamydial protease-like activity factorJulian Saba, Thermo Fisher Scientific, CanadaB-112QCloud: An automated community cloud-based system for quality control in proteomics experimentsEduard Sabidó, Centre De Regulació Genòmica, SpainB-113Peptide-mediated ‘miniprep’ for high-throughput isolation of extracellular vesicles coupled to phosphoproteomics.Tim Schelfhorst, Vumc, NetherlandsB-114Displacement chromatography in two-dimensional liquid–chromatography for proteomicsHartmut Schlueter, University Medical Center Hamburg-Eppendorf, GermanyB-115Increasing dynamic range and sample insight for top-down proteoform profling analysis.Pierre-olivier Schmit, Bruker Daltonics, FranceB-116Synthetic peptide reference standards for PTM proteomicsKarsten Schnatbaum, JPT Peptide Technologies GmbH, GermanyB-117Label-free microarrays for optimisation of protein and antibody bindingJulia Schuette, Biametrics Gmbh, GermanyB-118Plasma-derived microparticle biomarkers of paracetamol-induced hepatotoxicityDomitille Schvartz, University Of Geneva, Switzerland

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

B-119Automated proteolytic digestion for high precision peptide mapping and targeted bioanalysisAlexander Schwahn, Thermo Fisher Scientific, SwitzerlandB-120Simple, scalable and ultra-sensitive tip-based identification of protease substratesGerta Shema, Leibniz-institut Für Analytische Wissenschaften – Isas – E.v., GermanyB-121insSTAGE-diging: the in solution upgrade of STAGE-diging protocol for proteomic sample preparationPaolo Soffientini, Cogentech S.c.a.r.l., ItalyPhD Abstract Competition Winner – posters are located by the innovation stageB-122Understanding the protein corona of nanocarriers is a prerequisite for targeted drug deliveryJohanna Simon, Max Planck Institute For Polymer Research Mainz, GermanyB-123Complementary tandem mass spectrometry approaches to distinguishing peptides containing amino acid isoformsElizaveta Solovyeva, Moscow Institute of Physics and Technology (State University), Russian FederationB-124DigiWest based focused proteomics of irradiated human embryonic stem cells and neuroepithelial cellsDieter Stoll, Albstadt-Sigmaringen University Of Applied Sciences, GermanyB-125Automated, versatile and efficient sample clean-up using HILIC-functionalised magnetic microparticlesStoyan Stoychev, CSIR, South AfricaB-126A feasibility study of pitavastatin distribution in liver tissue by MALDI-mass spectrometry imagingYutaka Sugihara, Lund University, Sweden

B-127Quantitative assessment of the phosphoproteomes of kinase-deficient Escherichia coli strainsAbida Sultan, Novo Nordisk Foundation Center For Biosustainability, Technical University of Denmark, DenmarkB-128Impact Evaluation of Traditional Chinese medicine on Rat liver microsome P450s with mass spectrometryAihua Sun, Beijing Institute of Radiation Medicine; Beijing Proteome Research Center, ChinaB-129In vitro characterisation of terbinafine protein adductsArun Tailor, University Of Liverpool, United KingdomB-130Rapid production of virus protein microarray using protein microarray fabrication through gene synthesis (PAGES)Sheng-ce Tao, Shanghai Jiao Tong University, ChinaB-131Targeting single amino acid variants in melanoma cell lines by parallel reaction monitoringChristoph Täumer, Herr, GermanyB-132The forgotten proteome – approaches for the identification of short open reading frame encoded peptidesAndreas Tholey, Kiel University, GermanyB-133Characterisation and comparison of in-house produced Cetuximab with originator productAnne Trappe, National Institute For Bioprocessing Research & Training, IrelandB-134Relative protein quantification on model organismsChristian Treitz, IEM, Kiel University, Germany

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

B-135Structural characterization of glycoconjugates by using functional carbon materials with hydrolysis reaction in MALDI-MSMei-Chun Tseng, Institute Of Chemistry, Academia Sinica, TaiwanB-136Monitoring kinase activity using customized substrate peptidesKazuya Tsumagari, Graduate School of Pharmaceutical Sciences, Kyoto University, JapanB-137Enrichment strategies for improvement of mass spec analysis of chemical cross-linked peptidesRosa Viner, Thermo Fisher Scientific, United StatesB-138A novel MS-cleavable tag for the analysis of redox-sensitive cysteines by shotgun proteomicsSebastian Virreira Winter, Max Planck Institute Of Biochemistry, GermanyB-139Definition of the intracellular flucloxacillin-haptenated proteins that may have involvement in iDILIJames Waddington, University Of Liverpool, United KingdomB-140In-depth characterization of intact protein standards using top down mass spectrometry with multiple MSMS strategiesHongqian (Anige) Yang, Thermo Fisher Scientific, SwedenB-141Endoglycosidase-assisted high confident identification of intact glycopeptidesWantao Ying, Beijing Institute Of Radiation Medicine, ChinaB-142Development of mass spectrometric-based assays for in situ target identification of covalent inhibitorsKebing Yu, Genentech, United States

B-143Oxidation of protein-bound methionine in Photofrin-photodynamic therapy-treated human tumor cells explored by quantitative proteomics approachJau-song Yu, Molecular Medicine Research Center, Chang Gung University, TaiwanB-144Middle-down analysis of monoclonal antibody with ETD and UVPD on an Orbitrap Fusion Lumos MSVlad Zabrouskov, ThermoFisher Scientific, United StatesB-145Mevalonate pathway inhibitors as potential therapeutic agents for Hepatocellular carcinoma: an in vitro studyShamshad Zarina, National Center For Proteomics, University Of Karachi, PakistanB-146Targeted mass spectrometry to determine the stoichiometry of phosphorylation sites in proteinsLona Zeneyedpour, The Netherlands, NetherlandsB-147Quantitative profiling of glycerophospholipids during mouse and human macrophage differentiation using targeted mass spectrometryCuiping Zhang, Guangxi Medical University, ChinaB-148Toward a true quantitative protein atlasJiandi Zhang, Yantai Zestern Biotechnique Co. LTD, ChinaB-149Molecular proteomic characterization of greek single-breed dairy productsAthanasios Anagnostopoulos, Biomedical Research Foundation Of The Academy Of Athens, GreeceB-150Efficient micro-scale basic reverse phase peptide fractionation for global and targeted proteomicsSongyi Baek, Kbio, South Korea

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

B-151Improved top-down analysis on an Orbitrap Fusion Lumos with the advanced precursor determination algorithmHelene Cardasis, Thermo Fisher Scientific, United StatesB-152Multiplexed nucleic acid programmable protein arraysYang Liuhui, National Center For Protein Sciences, ChinaB-153Peptidomic analysis of rat plasma samples: effects of tranexamic acid against proteolysis in hemorrhagic shockElisa Maffioli, Università Degli Studi Di Milano, ItalyB-154A novel nanoflow LCMS limited sample proteomics approach using micro pillar array columns (µPAC™)Aran Paulus, Thermo Fisher, United StatesB-155Beta amyrin from the endophytic fungi Fusarium equiseti induce cell death in colon cancer cellsThulasi Pillai, Indian Institute Of Technology Bombay, IndiaB-156Proteomics analysis of historical collagen glue retrieved from a Stradivari violinHwan-ching Tai, National Taiwan University, TaiwanB-157Ultra-deep palmitoylomics enabled by a dithiodipyridine functionalized magnetic nanoparticlesXiaoqin Zhang, Fudan university, China

Methods, Systems & Bioinformatics

C-001Extracting peptide level quantification data from the PRIDE repositoryAndrea, Argentini, VIB-UGent Center for Medical Biotechnology Department of Biochemistry, Faculty of Medicine, Ghent University, BelgiumC-002Accurate LC retention time prediction for metabolites using calibrated predictionsRobbin, Bouwmeester, VIB-UGent, BelgiumC-003An automated and integrated SWATH-MS informatics pipeline for clinical proteomicsPaul, Brack, University Of Manchester, United KingdomC-004The Encyclopedia of Proteome Dynamics – A big data ecosystem for (prote)omicsAlejandro, Brenes, University Of Dundee, United KingdomC-005Search engine score independent re-scoring of PSMs using predicted Ion peak intensitiesAna S, C Silva, V.I.B. Universiteit Gent, BelgiumC-006N-Glycome changes in CHO cells due to extractable and leachable exposure from single-use bioreactorsSara, Carillo, Nibrt, IrelandC-007Making Annotated Spectra Available when Standard Formats are not an OptionRobert, Chalkley, University Of California San Francisco, United StatesC-008SPECTRUM: A MATLAB toolbox for identifying proteins from top-down proteomics dataSafee, Chaudhary, Lahore University of Management Sciences, Pakistan

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

C-009Integrated omics analyses of oral cancer in TaiwanTingwen, Chen, Chang Gung University, ChinaC-010Accurate prediction of retention time shift for isotopic-labeling based protein quantificationYeon, Choi, Seoul National University, South KoreaC-011Flexible data analysis for label-free time course proteomics experimentsLieven, Clement, Ghent University, BelgiumC-012Application of novel SILAC analysis software Proteolabels for large-scale meta-analysis of phospho-proteomesAndrew, Collins, University Of Liverpool, United KingdomC-013‘Omics’ exploration of the human tearsMarianne, Dor, University Of Geneva, SwitzerlandC-014BayesProt: Robust iTraq and TMT protein-level quantification and statistical analysis with a Bayesian mixed-effects modelAndrew, Dowsey, University Of Bristol, United KingdomC-015HD Proteome Base: A novel data repository for proteomics of a Huntington’s disease mouse modelSarah, Elschenbroich, Evotec (Muenchen) Gmbh, GermanyC-016Pathway analysis of altered kinases reveal gonadotropin hormone signaling in GlioblastomaPoonam, Gautam, National Institute of Pathology ICMR, IndiaC-017Integrated miRNA, mRNA and protein profiling of exosomes and their parental cellsLucia, Geis-Asteggiante, University of Maryland College Park, United States

C-018Efficient modelling of signalling networks derived from mass spectrometry phosphoproteomic data using Integer Linear ProgrammingEnio, Gjerga, Rwth Aachen University, GermanyC-019A user-friendly spectrum clustering software for optimised proteomics data analysisJohannes, Gris, Medical University Of Vienna, AustriaC-020Label-free quantitative proteomic analysis to investigate the effect of heat stress on Panax ginseng leavesRavi, Gupta, Pusan National University, South KoreaC-021The application of Commensal Computing for massively parallel analysis of proteomics dataJohn, Heap, Liverpool University, United KingdomC-022Reactome interactive pathway analysisHenning, Hermjakob, Embl-ebi, United KingdomC-023Comparison of pipelines for differential analysis of label free quantification experimentsVéronique, Hourdel, Institut Pasteur, FranceC-024Characterizing flame retardant-induced neurotoxicity in an hESC neural differentiation model using SWATH® Acquisition and RNA-SeqChristie, Hunter, Sciex, United StatesC-025UPS2 calibration set for biological matrix effect studyEkaterina, Ilgisonis, Ibmc, Russian FederationC-026PSI standards compatible binary mass spectrometry data format for efficient read/write speed and storage requirementsAndris, Jankevics, University of Bristol, United Kingdom

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

C-027The PRIDE database: A proteomics data “gold mine” at your disposalAndrew, Jarnuczak, European Bioinformatics Institute, United KingdomC-028Proteogenomic approaches to identify alternatively splicing variants in pancreatic cancer cell linesSeul-ki, Jeong, Yonsei Proteome Research Center, South KoreaC-029OmicsDI RDFShin, Kawano, Database Center for Life Science, Research Organization of Information and Systems, JapanC-030Unveiling the translational consequences of fusion genes and isoforms present in cancer using proteogenomics approachChae-Yeon, Kim, Yonsei University, South KoreaC-031Proteomic Cinderella: subtle analysis of bulky MS/MS data in one nightOlga, Kiseleva, Institute Of Biomedical Chemistry, Russian FederationC-032ADAR-mediated RNA editing in mouse brain proteomeAnna, Kliuchnikova, Institute Of Biomedical Chemistry, Russian FederationC-033Benchmarking data-independent acquisition workflows using hybrid proteome samples and LFQbenchJoerg, Kuharev, University Medical Center Of The Johannes Gutenberg University, GermanyC-034Methionine-to-isothreonine conversion during sample preparation and its effects on proteomic dataKsenia, Kuznetsova, Institute Of Biomedical Chemistry, Russian FederationC-035Label free quantitation: comparative analysis of XIC and SpCs based methodsAlfredo, Landolfi, University of Naples - “Federico II”; CEINGE - Biotecnologie Avanzate, Italy

C-036Efficient proteomic and proteogenomic searches with IdentiPyLev, Levitsky, INEPCP RAS, Russian FederationC-037UbiBrowser: an integrated bioinformatics platform for investigating human ubiquitin ligase (E3) - substrate interaction networkDong, Li, No. 59, Middle Road of West 4th Ring Road, Beijing, China, ChinaC-038Integrated data analysis pipeline for meta-omicsSujun, Li, Indiana University, United StatesC-039iProX: the integrated proteome resources in ChinaMansheng, Li, beijing proteome research center, ChinaC-040The “Quantify then Identify” pipeline: a promising tool to minimize unexploited spectral informationCharlotte, Macron, Nestlé Institute of Health Sciences SA, SwitzerlandC-041lcmsWorld: A high-performance 3D software visualisation tool for LC/MS dataAntony, Mccabe, University Of Liverpool, United KingdomC-042SwathXtend modules to improve protein detection confidence using SWATH-MS with large peptide spectral reference librariesMark, Molloy, Australian Proteome Analysis Facility (APAF), AustraliaC-043Development of integrated proteomics database: jPOSTYuki, Moriya, Database Center For Life Science, Research Organization Of Information And Systems, JapanC-044Proteogenomics of ADAR-mediated RNA editing in Drosophila melanogasterSergei, Moshkovskii, Institute Of Biomedical Chemistry, Russian Federation

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

C-045Protein- and Background- based ANOVA inference in proteomic analysesPedro, Navarro, Thermo Fisher Scientific (Bremen) GmbH, GermanyC-046RiboZinB: Identifying the actively translated isoform. The case of the Zero-inflated modelElvis, Ndah, University Of Gent, BelgiumC-047jPOST provides a global public data repository for a wide variety of proteomics experimentsShujiro, Okuda, Niigata University, JapanC-048Serving protein interaction data to the community – the HUPO-PSI Molecular Interaction WorkgroupSandra, Orchard, European Bioinformatics Institute (EMBL-EBI), United KingdomC-049Analytica: software for LC-MS omics data analysis and visualisationSimon, Perkins, University Of Liverpool, United KingdomC-050Advanced centroiding of low resolution MS/MS Spectra provides higher confidence identifications from proteomics datasetsJeff, Peterson, Veritomyx, United StatesC-051Statistical analysis of ion intensities in label-free tandem mass spectrometry-based proteomicsThang V, Pham, Vu University Medical Center, NetherlandsC-052Proteomics space odyssey: strategy of proteoforms scoutingEkaterina, Poverennaya, Ibmc, Russian FederationC-053Benchmarking statistical approaches for label-free quantitative proteomicsHayley, Price, University Of Liverpool, United KingdomC-054Serum degradation analysis by MALDI/ToF: a new method and toolAldo, Profumo, Ospedale Policlinico San Martino, Italy

C-055Large scale integration of proteomics and genomics data to enhance rice genome annotationDa, Qi, University of Liverpool, United KingdomC-056Geena2 - a public tool for the automation of MALDI/ToF spectra pre-processingPaolo, Romano, Ospedale Policlinico San Martino, ItalyC-057A compendium of co-regulated protein complexes in breast cancer reveals collateral loss eventsColm J., Ryan, University College Dublin, IrelandC-058ProteomicsDB transforms into an interactive multi-omics platformPatroklos, Samaras, Chair Of Proteomics And Bioanalytics, GermanyC-059Quantitative analysis of protein, mRNA and miRNA response to hypoxia in primary hippocampal neuronsChristian, Schiffmann, Department of Psychiatry and Psychotherapy, University Medical Center Göttingen (UMG), GermanyC-060ProteomicsDB enables custom spectral library and transition list generationTobias, Schmidt, Chair of Proteomics and Bioanalytics, GermanyC-061COSS: Free, fast and powerful CompOmics spectral search toolGenet Abay, Shiferaw, Ghent University, BelgiumC-062Novel permutation scheme improves accuracy of permutation-based false discovery rate estimation in quantitative proteomicsPavel, Sinitcyn, Max Planck Institute Of Biochemistry, GermanyC-063mass-spectrometrists should search for all peptides, but assess only the ones they care aboutAdriaan, Sticker, Vib-ugent, Belgium

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

C-064Integrating simulated spectral libraries into proteomics data analysis workflow for improved phosphosite identificationVeronika, Suni, Turku Centre For Biotechnology, University Of Turku and Åbo Akademi, FinlandC-065Understanding the effect of Deisotoping MS/MS Spectra on protein identificationAidan, Tay, University Of New South Wales, AustraliaC-066Fast and accurate protein false discovery rates on human proteome study scale with Percolator 3.0Matthew, The, Kth Stockholm, SwedenC-067Colims: a distributed proteomics LIMS systemDemet, Turan, VIB, BelgiumC-068ProteoRE, a Galaxy-based infrastructure for annotating and interpreting proteomics dataYves Vandenbrouck, cea, Fundamental Research Division, BIG institute, FranceC-069Cross-linked peptide identification: a single answer from many tools?Elien, Vandermarliere, Vib-ugent, BelgiumC-070Large-scale discovery and quantitation of novel peptides using omics derived librariesVidya, Venkatraman, Cedars-Sinai Medical Center, United StatesC-071An integrative multi-omics approach for improved discovery of biomarkers related to prostate cancer progressionSarah, Wagner, John Van Geest Cancer Research Centre, United KingdomC-072Bringing proteomics data analysis into the cloudMathias, Walzer, EMBL-EBI, United KingdomC-073P-Mart - Interactive online software to analysis and exploration from global proteomic datasetsBobbie-Jo, Webb-Robertson, Pacific Northwest National Laboratory, United States

C-074PepQuery: a peptide-centric search engine that makes proteomics data directly usable to the genomics communityBo, Wen, Baylor College of Medicine, United StatesC-075MaxQuant Top-Down: a multifunctional software package for quantitative top-down proteomicsChristoph, Wichmann, Max-Planck Institute of Biochemistry, GermanyC-076PMD: a resource for archiving and analyzing protein microarray dataZhaowei, Xu, Shanghai Jiao Tong University, ChinaC-077Improved detection sensitivity of quantitative changes for low-abundant proteins by data curation of PLGEM-STN p-valuesSan-Duk, Yang, Seoul National University, South KoreaC-078Reducing false positive identifications for proteome datasets accumulated in jPOST repositoryAkiyasu C., Yoshizawa, Graduate School of Pharmaceutical Sciences, Kyoto University, JapanC-079AAgAtlas 1.0: a human autoantigen databaseXiaobo, Yu, Beijing Proteome Research Center, ChinaC-080Quality control of mass spectrometry proteomics data integration in neXtProtMonique, Zahn, SIB Swiss Institute Of Bioinformatics, SwitzerlandC-081Integrated multi-omics characterization of neuroblastomaMatthias, Ziehm, Max-Delbrück-Center For Molecular Medicine (MDC), GermanyC-082Intelligent solution for mass spectrometry-based proteomicsZhuoxin, Chen, Fudan University, China

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C-083MS/MS-free protein identification in complex mixtures using multiple enzymes with complementary specificityMark, Ivanov, Moscow Institute of Physics and Technology, Russian FederationC-084Multiomics data integration using ontologiesMagnus, Palmblad, Leiden University Medical Center, NetherlandsC-085A protocol for finding missing proteinsShoba, Ranganathan, Macquarie University, AustraliaC-086Up to ~10,000x faster DIA processing using deepsearch: results during your coffee breakGautam, Saxena, DeepDIA, United States

Disease & Clinical Proteomics

D-001Comparative proteome analysis of long-term survivor and non-survivor patients with acute myeloid leukemiaElise Aasebø, University Of Bergen, NorwayD-002PhD abstract competition winner. Poster will be located by the innovation stage Suppression of colorectal cancer proliferation and invasion by antagonising uPAR•αvβ6 interactionSubash Adhikari, Macquarie University, AustraliaD-003Identification and localization of protein-pentanal adducts, a potential lipoxidation markerCatarina Afonso, Aston University, United KingdomD-004Detection of plasma colorectal cancer prognostic biomarkersSeong Beom Ahn, Macquarie University, AustraliaD-005Identification of serum proteins that can delineate acute Hantavirus infectionStuart Armstrong, University Of Liverpool, United Kingdom

D-006The role of cardiac metabolism perturbation in radiation-induced human heart disease: a proteomics analysisOmid Azimzaeh, Helmholtz Zentrum München, Radiation Proteomics, GermanyD-007Quantitative proteome analysis of VEGF-induced vascular hyperpermeability in a mouse model by LC-MS/MSJingi Bae, Korea University, South KoreaD-008Proteomic profiling of secretomes from M.tb-stimulated, PUFA-treated, ex vivo PBMCs in TB-IRISMarine Barnabe, University Of Cape Town, South AfricaD-009Novel target identification in Alzheimer’s disease brain by combined mass spectrometry imaging and subcellular proteomicsJoakim Bastrup, Aalborg University, DenmarkD-010Differential proteomic analysis of metformin response in a preoperative window clinical trial for endometrial cancerNicholas Bateman, Gynecologic Cancer Center Of Excellence, United StatesD-011Biomarker search in prostate cancer by proteomic approachFeyza Bayramoglu, Istanbul Medipol University, TurkeyD-012Evaluation of synaptic proteins as cerebrospinal fluid stage biomarkers for Alzheimer’s diseaseOlivia Belbin, IIB-SantPau, SpainD-013Cytoskeleton and nuclear lamina affection in Osteogenesis imperfecta: a functional proteomics perspective.Laura Bianchi, Siena University, Italy

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

D-014Proteomics signature in early remodeling after myocardial ischemia/reperfusion and the effects of experimental treatmentsAleksandra Binek, Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), SpainD-015Identification of candidate prostate cancer biomarkers in urinary extracellular vesicle proteins by label-free LC-MS/MS-based proteomics.Irene Bijnsdorp, Vu University Medical Center, NetherlandsD-016Protein signature for endometrial cancer diagnosis in exosome-like vesicles of uterine aspiratesEva Borras, Center for Genomic Regulation, SpainD-017Response prediction for platinum-based treatment regimens in non-small cell lung cancer using a protein-based assayFranziska Böttger, VU University Medical Center, NetherlandsD-018Affinity MS identifies pre-synaptic proteins SNAP-25 and synaptotagmin-1 as novel CSF biomarkers for Alzheimer’s diseaseAnn Brinkmalm, University Of Gothenburg, SwedenD-019Novel CSF tau fragments as candidate biomarkers for Alzheimer’s and other neurodegenerative diseasesGunnar Brinkmalm, University Of Gothenburg, SwedenD-020Extracellular matrix proteomics reveals Aggrecan and Aggrecanases as novel contributors to vascular remodeling after stentingSean Burnap, King’s College London, United Kingdom

D-021Alterations to HDL protein composition in abdominal aortic aneurysm patientsEmilio Camafeita, CNIC, SpainD-022Proteomic characterization of new transcription factors associated with a more invasive phenotype in colorectal cancerIgnacio Casal, Centro de Investigaciones Biológicas, SpainD-023Boiling produces hypoallergenic cashew nuts with potential to safely desensitize affected patientsTim Chataway, Flinders University, AustraliaD-024Increased electronegativity of high density lipoproteins impairs its functional properties and increases risk of CADChao-jung Chen, China Medical University, TaiwanD-025Proteomic analysis of plasma-derived extracellular vesicles in breast cancer PDX modelsJia-Xuan Chen, Cancer Research UK Cambridge Institute, United KingdomD-026Phosphoproteomics analysis of plasma from Vietnamese type 2 diabetes patientsPhan Van Chi, Vietnam Academy Of Science & Technology, Viet NamD-027Proteomic analysis of extracellular vesicles from clinically available volumes of CSF: application to Alzheimer’s diseaseDavide Chiasserini, VU University Medical Center, NederlandD-028Development of serum protein biomarkers for the recurrence in gastric cancers using multiple reaction monitoringByoung-kyu Cho, Seoul National University, South Korea

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

D-029Phosphoproteomics study reveals the regulation of vasodilator-stimulated phosphoprotein upon stathmin-1 silencing in colorectal cancer metastasisMaxey CM Chung, National University Of Singapore, SingaporeD-030Identification, validation and characterisation of membrane protein tumour markers for pancreatic adenocarcinomaOrla Coleman, Dublin City University, IrelandD-031The differential plasma proteome of obese and overweight individuals undergoing nutritional weight loss and maintenanceOrnella Cominetti, Nestle Institute Of Health Sciences, SwitzerlandD-032Use of MALDI imaging technology to predict the response to antiangiogenic therapy in colorectal cancerFrancisco Conde, Instituto Maimonides De Investigacion Biomedica De Cordoba, SpainD-033Investigating the potential of exosomes as biomarkers in Cystic FibrosisJudith Coppinger, Royal College Of Surgeons In Ireland, IrelandD-034Tear protein analysis in the different phases of wound healing following glaucoma surgeryEva Csosz, University Of Debrecen, HungaryD-035Gut-brain axis in ageing: a proteomics approachAlfonsina D’Amato, Quadram Institute Bioscience, United KingdomD-036SDS vs urea: fast and sensitive non-mechanical conversion of tissues to peptidesIrena Dapic, Van’t Hoff Institute For Molecular Sciences, Netherlands

D-037MS/MS strategies to characterize the Proteoform landscape in human tears using top-down mass spectrometryClaire Dauly, Thermo Fisher Scientific, FranceD-038Peptidomics: an innovative approach to study the “Auto-digestion” hypothesis in septic shock patientsEliandre de Oliveira, Barcelona Science Park, SpainD-039Verification of saliva proteins candidates for OSCC markers and their correlation with prognosisTatiane De Rossi Mazo, Brazilian Biosciences National Laboratory (LNBio), BrazilD-040Novel stool-based protein biomarkers for improved colorectal cancer screening: a case-control studyMeike De Wit, The Netherlands Cancer Institute, NetherlandsD-041Proteomics of the intestinal mucosal-luminal interface identifies biomarkers to improve pediatric inflammatory bowel disease diagnosisShelley Deeke, University Of Ottawa, CanadaD-042Novel osteoporosis risk protein biomarkers suggested by a proteome study in Chinese elderly menFei-Yan Deng, Soochow University, ChinaD-043Quantitative proteomics to investigate the effects of a pMRTP and smoking cessation on mouse lungSophie Dijon, PMI, SwitzerlandD-044Combinatorial mass spectrometry (MS) and artificial intelligence (AI) subclassification of diffuse gliomaUgljesa Djuric, University Health Network, CanadaD-045Affinity proteomic profiling of plasma for proteins associated to pancreatic cancerTea Dodig-crnkovic, Affinity Proteomics, Science For Life Laboratory, School Of Biotechnology, Royal Institute Of Technology (kth), Sweden

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

D-046In-depth quantitative mass spectrometry reveals the region and cell-type resolved proteome of the human heartSophia Doll, Max Planck Institute Of Biochemistry, GermanyD-047Bridging the ‘translation gap’: a prospective study to validate biomarker panels predictive of prostate cancerWill Dracup, Biosignatures, United KingdomD-048Dynamic composition of the Cryptococcus neoformans proteome and secretome during dormancy phenomenonMagalie Duchateau, Institut Pasteur, FranceD-049Adipocyte exosomes promote melanoma aggressiveness through fatty acid oxidation: novel mechanism linking obesity and cancerManuelle Ducoux-petit, IPBS/CNRS/UPS, FranceD-050Linking genotype to clinical phenotype through SWATH-MS analysis of chronic lymphocytic leukaemia trial samplesGina Eagle, University Of Liverpool, United KingdomD-051Comparative proteomic study of affected and non-affected tissues of clubfootAdam Eckhardt, Fgu AVČR, Czech RepublicD-052Revealing histone variants by targeted proteomic analysis using the manually curated database MS_HistoneDBSara El Kennani, Cea, FranceD-053Proteomics analysis and lysine acetylation stoichiometry in cancer cellsSergio Encarnacion-Guevara, Universidad Nacional Autónoma de México, MéxicoD-054HDMSE proteomic analysis of the mode of action of short chain fatty acids in colonCaroline Evans, University Of Sheffield, United Kingdom

D-055Protein biomarker discovery in Alzheimer’s disease using SWATH MS analysisLaura Farrell, Stoller Biomarker Discovery Centre, Uom, United KingdomD-056Protein crossroads: Dementia vs. Alzheimer’s DiseaseJustyna Fert-Bober, Cedars-sinai Medical Center, United StatesD-057Establishment of the hnRNP C1/C2 role on schizophrenia through protein interaction network mappingMariana Fioramonte, University Of Campinas, BrazilD-058Social defeat stress: a plasma proteomic study to identify stress susceptible-associated and resilience-associated biomarkersMelanie Focking, Royal College Of Surgeons In Ireland, IrelandD-059Quantification of PI3K/AKT/mTOR signalling pathway activity using immuno-MALDI mass spectrometry (iMALDI)Bjorn Frohlich, University Of Victoria, CanadaD-060Integrated investigation into characteristics of proteome, genome and transcriptome of rectal cancer with liver metastasisYanning Gao, National Cancer Center/cancer Hospital, Chinese Academy Of Medical Sciences, ChinaD-061Changes of urinary proteins in a bacterial meningitis rat modelYouhe Gao, BEIJING NORMAL UNIVERSITY, ChinaD-062Early detection in urinary proteome for effective treatment of bleomycin-induced pulmonary fibrosis in rat modelYouhe Gao, Beijing Normal University, China

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

D-063The analysis and identification of STAT3 interactions and modifications in the mitochondria of cancer cellsDaniel Garama, Hudson Institute Of Medical Research, AustraliaD-064First direct evidence of cross-linked Aβ dimers in the brains of Alzheimer’s disease patientsMarina Gay, IRB Barcelona, BIST, SpainD-065Proteomics reveals associations between protein abundance and sepsis phenotypesManuela Gesell Salazar, Department Functional Genomics, University Medicine Greifswald, GermanyD-066Online 2D-LC intact proteins separation for deeper shotgun proteomics of serum samplesNatalia Govorukhina, Rug, NetherlandsD-067Combined biomarker panel shows improved sensitivity for the early detection of ovarian cancerCiaren, Graham, Manchester Metropolitan University United KingdomD-068Proteomics of rare genetic diseases: impact of cystinosin mutations on protein stability and protein networkIda Chiara Guerrera, Inserm, FranceD-069Discovery of the proteomic profile to predict the renal function decline in kidney diseaseReyna Gutierrez Rivera, The Stoller Biomarker Discovery Centre, United KingdomD-070Landscape of proteomic alterations in cervical carcinomas through laser microdissection samplingCoskun Guzel, Erasmus MC, NetherlandsD-071MALDI-TOF mass spectrometry on the track of sand fly life cyclePetr Halada, Institute of Microbiology, Czech Republic

D-072OMICS based stratification of dilated cardiomyopathy patientsElke Hammer, University Medicine Greifswald, GermanyD-073In-depth proteome profiling of formalin-fixed paraffin-embedded urothelial carcinoma and benign disease tissuesDohyun Han, Seoul National University Hospital, South KoreaD-074Proteomic study on advanced glycation end-products treatment in kidney of miceEun Hee Han, Korea Basic Science Institute (kbsi), South KoreaD-075To deplete or to equalize? Two pre-analytical strategies for human cerebrospinal fluid analysisKarel Harant, Faculty Of Science Charles University In Prague, Czech RepublicD-076Tissue specific secretomes, the hidden treasure for identification of disease related marker proteinsSonja Hartwig, DDZ, DeutschlandD-077Systematic development of sandwich immunoassays for the analysis of the secretome in plasmaRagna S. Häussler, Science For Life Laboratory, SwedenD-078Applying a targeted proteoform profiling method for neurological disorder biomarker discoveryRomano Hebeler, Bruker Daltonik GmbH, GermanyD-079Early warning signals of aging in the hematopoietic stem cell nicheMarco L. Hennrich, Embl, GermanyD-080Design of a targeted proteomics assay for the diagnosis of invasive candidiasisMaria Luisa Hernaez, Complutense University, Spain

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

D-081Impact of peritoneal dialysis fluid on O-GlcNAcylation of the mesothelial cell proteome and cell survivalRebecca Herzog, Medical University Of Vienna, AustriaD-082Gender-enhanced alteration in airway epithelial proteome in COPD related to xenobiotic metabolismTina Heyder, Karolinska Institutet, SwedenD-083Glycosylation changes of cell membrane proteins in pancreatic cancerYoshimi Higashi, Hiroshima University, JapanD-084How can we effectively detect biomarker candidates by mass spectrometry?Hisashi Hirano, Yokohama City University, JapanD-085Analysis of an amyloid aggregation conformational conversion of TDP-43 in neurodegenerative diseasesYi-Chi Ho, Institute Of Chemistry, Academia Sinica, TaiwanD-086Proteome-wide study of cerebrospinal fluid biomarkers for bipolar disorder and other neuropsychiatric disordersJessica Holmén Larsson, University of Gothenburg, SwedenD-087The power of multiplexing- combining TMT discovery and targeted label free quantitation for biomarker analysisAndreas Huhmer, Thermo Fisher Scientific, United StatesD-088Dissecting the TRIM8 role in the pathogenesis of glioblastomaIlaria Iacobucci, University of Naples “Federico II” , Ceinge Advanced Biothecnology, ItalyD-089Phosphoproteome and sialome of cells modelling tumour infiltrating myeloid populationsMaria Ibáñez-Vea, Navarrabiomed Biomedical Research Centre, Navarra Institute for Health Research (IdiSNA), Spain

D-090Investigation of the lymphatic malformation cystic fluid and plasma proteomesVera Ignjatovic, Murdoch Children’s Research Institute, AustraliaD-091Unraveling amyloid beta-pathology in Alzheimer’s disease with MALDI imaging mass spectrometryMasaya Ikegawa, Doshisha University, JapanD-092Extraction and analysis of Aβ fractions of the peptidome from human blood componentsMaria Indeykina, IBCP RAS, Russian FederationD-093Identification of candidate diagnostic serum biomarkers for Kawasaki disease using proteomic analysisYoko Ino, Yokohama City University, JapanD-094Lacrimal proteome: possible source of biomarkers?Tamas Janaky, Department of Medical Chemistry, University of Szeged, HungaryD-095Plasma proteins associated with advanced liver fibrosis in patients with nonalcoholic fatty liver diseaseMichael Janech, Medical University of South Carolina, United StatesD-096The human neutrophil: improved proteome coverage and clinical insightsPeyper Janique, University of Cape Town, South AfricaD-097In-depth proteome-profiling to evaluate a novel combinatory metronomic treatment for therapy-resistant multiple myeloma patientsLukas Janker, University Of Vienna - Department Of Analytical Chemistry, AustriaD-098Integrative analysis of transcriptomic and proteomic data from testicular tissues of Liver-X receptor knockout miceSheba Jarvis, Imperial College, United Kingdom

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

D-099Plasma membrane proteomic analysis of host protein expression in response to Enterovirus 71 infectionXiaofang Jia, Shanghai Public Health Clinical Center, ChinaD-100Development of a nonglycopeptide-based MRM strategy for screening of differential glycoproteins in hepatocellular carcinomaBiyun Jiang, Fudan University, ChinaD-101Serum fragment of TSP1 as a biomarker for metastasis and poor prognosis of ESCCZongpan Jing, National Cancer Center.The State Key Laboratory of Molecular Oncology., ChinaD-102Annexin A3 as potential biomarker in first-onset psychosisHelena Joaquim, Neuroscience Laboratory - Fmusp, BrazilD-103Autoantibody profiling in schizophrenia affected brain tissuesDavid Just, Science for Life Laboratory, School of Biotechnology - KTH, Royal Institute of Technology, SwedenD-104Protein modification and the immune system; a ménage a trois gone wrong in Multiple SclerosisKenneth Kastaniegaard, Aalborg University, DenmarkD-105DCBLD2 is a novel biomarker of myxofibrosarcoma invasion identified by global protein expression profilingKazutaka Kikuta, Department Of Orthopedic Surgery, Keio University School Of Medicine, JapanD-106Oxidized methionine levels in serum proteins as potential clinical biomarkers to assess oxidative stress statusYoshio Kodera, Kitasato University, JapanD-107Proteomics for rare cancer: Lesson learned from Sarcoma biomarker researchTadashi Kondo, National Cancer Center, Japan

D-108Immunomodulatory effects of peritoneal alanyl-glutamine in clinical peritoneal dialysis detected by a multi-omics biomarker approachKlaus Kratochwill, Medical University Of Vienna, AustriaD-109The quantitative proteomic study of human saliva samples obtained from caries-free and caries-susceptible peopleLucie Kulhavá, Charles University, Czech RepublicD-110Phosphoproteomic profiling of heart tissue: from mouse model to patient samplesUros Kuzmanov, University Of Toronto, CanadaD-111Imaging mass spectrometry of kidney from type 2 Diabetes (T2D) rat modelYuki Kuzuhara, Doshisha University, JapanD-112Proteomics investigation of Wilson’s disease pathophysiology in the ATP7B-/- murine modelMaud Lacombe, CEA Grenoble, FranceD-113Biomarkers to differentiate between CT-positive and CT-negative patients with mild traumatic brain injuryLinnea Lagerstedt, University Of Geneva, SwitzerlandD-114Functional analysis in pulmonary systemic sclerosisClaudia, Landi, University Of Siena, ItalyD-115Quantitative phosphoproteomics reveals T cell signaling drives HIV-1 spreadAlice Len, University College London, United KingdomD-116Super-SILAC mix coupled with SIM/AIMS assays for targeted verification of phosphopeptides discovered in hepatocellular carcinomaYu-Tsun Lin, Molecular Medicine Research Center, Chang Gung University, Taiwan

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

D-117Chronic administration of methylmercury induces differential proteome changes in different regions of mammalian brainsSamuel CL Lo, Hong Kong Polytechnic University, Hong KongD-118Glycosylation analysis of prostate specific antigen – towards improved diagnosis of prostate cancerStephen Lock, Sciex, United KingdomD-119Vascular niche E-selectin plays a key role in leukemia chemo-resistanceDorothy Loo Oey, Translational Research Institute, AustraliaD-120Identification of nephropathy predictive markers in urine from children affected by type-1 diabetesCinzia Magagnotti, San Raffaele Scientific Institute, ItalyD-122Plasma protein targets for early detection and monitoring of sinusoidal obstruction syndromePavel Majek, Institute Of Hematology And Blood Transfusion, Czech RepublicD-12314-3-3 σ/Stratifin as candidate biomarker for smokeless tobacco associated Oral Squamous Cell Carcinoma in PakistanUzma Urooj Malik, National Center For Proteomics, University Of Karachi, PakistanD-124Temporally- & spatially-resolved microproteomics and MALDI MSI lipidomic analysis for traumatic brain injury biomarker identificationKhalil Mallah, Laboratoire Protéomique, Réponse Inflammatoire Et Spectrométrie De Masse (prism) Inserm U1192- Université Lille 1, FranceD-125Monitoring oxidative stress and progression to cell death: are we closer to Parkinson’s disease diagnosis?Bruno Manadas, Center For Neuroscience And Cell Biology - University Of Coimbra, Portugal

D-126µZIC-HILIC-MS/MS methodology for the characterization of N-glycan isomersMontserrat Mancera Arteu, University of Barcelona, SpainD-127Old dog with new tricks: Tear proteome changes associated with renouncement of contact lensesCaroline Manicam, Department Of Ophthalmology, University Medical Centre of the Johannes Gutenberg University Mainz, GermanyD-128Proteomic characterization of neuromelanin granules isolated from human substantia nigra by laser-microdissectionKatrin Marcus, Medizinisches Proteom-center, Ruhr-university Bochum, GermanyD-129Identification of signaling pathways involved in colorectal adenoma-to-carcinoma progressionSanne Martens-de Kemp, VU University Medical Center, NetherlandsD-130A proteomics approach to subclinical atherosclerosisDiego Martínez López, FIIS-Fundación Jiménez Díaz-Universidad Autónoma, SpainD-131Glycan profiling for exploring relationship of MUC1 O-glycoform with tumor-characteristic by lectin microarrayAtsushi Matsuda, Depertment Of Biochemistry, Keio University, JapanD-132Combined proteomics and metabolomics approach for the investigation of metabolic deregulations in chronic lymphocytic leukemiaRupert Mayer, University Of Vienna, Department Of Analytical Chemistry, AustriaD-133Revealing the systemic disorders underlying environmental enteropathy using in vivo proteomics of SILAC-mice, and metabolomicsJames McCoy, University Of British Columbia, Canada

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

D-134Epidermal barrier improvement after Excipial application in atopic xerosis is revealed by non-invasive proteome analysis.Bruno Mehul, Nestle Skin Health / Galderma, FranceD-135Human neocortex proteome profiling during progression of tau pathology in Alzheimer’s diseaseClarissa Mendonça, Federal University Of Rio De Janeiro, BrazilD-136Proteomic analysis of glomerular extracellular matrix proteomes differentiates FSGS variantsMichael Merchant, University Of Louisville, United StatesD-137Quantitative determination of specific serum IgG; diagnosis of Staphylococcus aureus bloodstream infection as an exampleStephan Michalik, University Medicine Greifswald, GermanyD-138Phosphoproteome profiling of different clinical phases in multiple myelomaJuho Miettinen, Institute for Molecular Medicine Finland (fimm), University of Helsinki, FinlandD-139Affinity proteomics identifies proteins associated with asthma severityMaria Mikus, SciLifeLab, KTH - Royal Institute of Technology, SwedenD-140PhD abstract competition winner. Poster will be located by the innovation stageTissue proteomics unravel EIF3D as a potential candidate associated with bladder cancer invasionMarika Mokou, Biomedical Research Foundation Academy Of Athens, GreeceD-141Multi-omics analysis of esophageal adenocarcinoma: how lipid metabolism affects cancer progressionJeffrey Molendijk, University Of Queensland, Australia

D-142Identification of new early biomarkers of Diabetic Nephropathy using proteomic approachesLaurence MOLINA, CNRS UMR 9005, FranceD-143ProLiPALS: Proteomics of Lymphocytes from Parkinson’s disease and Amyotrophic Lateral Sclerosis patients.Chiara Monti, University Of Insubria, ItalyD-144Standardising and harmonising multiple TripleTOF® systems for proteomics using a dedicated SWATH® acquisition performance kitNicholas Morrice, Sciex, United KingdomD-145Securitized production of stromal stem cells for therapy: Proteomic investigation on genetic stability and senescenceEmmanuelle Mouton Barbosa, Ipbs Cnrs, FranceD-146Characterization and identification of dityrosine cross-linked peptides using tandem mass spectrometrySoumya Mukherjee, The Florey Institute of Neuroscience and Mental Health, AustraliaD-147Reproducible in-depth proteome analysis of formalin-fixed paraffin-embedded tissues by data independent acquisition methodJan Muntel, Biognosys AG, SwitzerlandD-148Proteomic identification of elevated serum haptoglobin levels in dystrophinopathySandra Murphy, Maynooth University, IrelandD-149Potential biomarkers in the urine of babies with ROPKrishna Murthy, Vittala International Institute Of Ophthalmology, IndiaD-150Proteomic assessment of HIV-Tat Treated human neurons: towards a molecular model for HIV-associated neurocognitive disordersBrandon Murugan, University of Cape Town, South Africa

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

D-151Analyses of glycans on haptoglobin in sera of patients with various types of cancerMiyako Nakano, Hiroshima University, JapanD-152Comparative proteomic analysis of mouse kidney with systemic lupus erythematosusOrthodoxia Nicolaou, Cyprus Institute Of Neurology & Genetics, CyprusD-153Plasma proteome analysis enables accurate quantification of liver-secreted proteinsLili Niu, Novo Nordisk Foundation Center For Protein Research , University Of Copenhagen, DenmarkD-154MS-based epigenetic profiling of breast cancer samples for patient stratification and discovery of novel targetsRoberta Noberini, Fondazione Istituto Italiano Di Tecnologia, ItalyD-155iTRAQ labeling and label-free quantitative proteome analysis of synaptosome from schizophrenic patientsFábio Nogueira, Ufrj, BrazilD-156Proteomics as part of systems toxicological assessment of a mentholated candidate modified risk tobacco productCatherine Nury, Philip Morris International, SwitzerlandD-157MRM of synucleins in CSF reveals alterations in Alzheimer´s and Creutzfeldt-Jakob disease but not synucleinopathiesPatrick Oeckl, Ulm University Hospital, Department Of Neurology, GermanyD-158Quantitative proteomic analysis of vitreous humor from idiopathic epiretinal membrane and macular hole patientsTiina Öhman, Institute Of Biotechnology, University Of Helsinki, FinlandD-159Proteomics of post-translational lysine acetylation in glioma-derived stem cellsHiroki Okanishi, Kumamoto University, Japan

D-160Proteomics as a tool in revealing the biology of thyroid eye diseaseGarrett Ong, Singapore General Hospital, SingaporeD-161Methylglyoxal-modified peroxiredoxin 6 as a biomarker for diabetic complicationsTomoko Oya-ito, Shubun University, JapanD-162Lung cancer biomarker discovery using integrated transcriptomics and proteomics approachJisook Park, Samsung Medical Center, South KoreaD-163Correlation of histopathologic characteristics to protein expression and function in malignant melanomaKrzysztof Pawłowski, Lund University, SwedenD-164Proteome changes of extracellular vesicles isolated from the plasma of myelodysplastic syndrome patientsKlara Pecankova, Institute Of Hematology And Blood Transfusion, Czech RepublicD-165Thermal profiling of breast cancer cells reveals proteasomal activation by CDK4/6 inhibitor palbociclibJulien Peltier, Institute For Cell And Molecular Biosciences (icamb), United KingdomD-166Proteoforms of transthyretin - candidate biomarkers in diagnosis of obstructive sleep apneaDeborah Penque, Instituto Nacional de Saude dr Ricardo Jorge, PortugalD-167Identification of tear fluid biomarkers in dry eye and glaucoma patients using targeted proteomics strategyNatarajan Perumal, University Medical Center Of The Johannes Gutenberg University Mainz, Germany

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

D-168Toxins of Clostridium difficile reorganize the proteome of target cellsAndreas Pich, Hannover Medical School, Germany

D-169Proteomic insights in extracellular microvesicles from CSF and tears of multiple sclerosis patientsDamiana Pieragostino, University “G. d’annunzio” Of Chieti- Pescara, Italy

D-170Proteomic investigation supporting behavioural characterization of recovery upon DHA treatment of Spinal Cord Injury (SCI)Luisa Pieroni, IRCCS Fondazione S.Lucia, ItaliaD-171Differential protein expression related to testosterone deficiency in healthy men. a quantitative proteomics studyIndira Plá, Lund University/BMC, SwedenD-172MRM based absolute quantification of myeloid derived growth factorFelix Polten, Medical School Hannover, GermanyD-173Proteomics identified predictive biomarkers for response to treatment with pazopanib in sarcomaZhiwei Qiao, National Cancer Center Research Institute, Japan, JapanD-174Proteomic Analysis of Staphylococcus aureus Planktonic and Hydrated Biofilms using TMT-based Mass SpectrometryMd. Arifur Rahman, Macquarie University, AustraliaD-175Deregulation of immunological pathway in chronic schizophrenia analysed by quantitative proteomicsRavikumar Raju, National Institute Of Mental Health And Neuro Sciences, India

D-176HIV Latency: deep-proteome coverage reveals the extent of cellular awareness of HIV and immunotherapy targetsSri, Ramarathinam, Monash University, Australia

D-177Understanding differential signaling via toll like receptor-2 by multipronged quantitative proteomicsNagender Rao Rameshwaram, Centre For DNA Fingerprinting & Diagnotics, IndiaD-178Role of posttranslational modifications on potential blood-based protein biomarkers in Alzheimer’s diseaseChaminda Ranasinghe, Edith Cowan University (ECU), AustraliaD-179Post-translational modifications (PTMs) of huntingtin protein in Huntington’s diseaseTamara Ratovitski, Johns Hopkins University, United StatesD-180Studying mechanisms using omics-based approaches in ischemia reperfusion injury associated with kidney transplantShelby Reid, University Of Toronto, CanadaD-181Profiling basement membrane proteins in plasma and cerebrospinal fluid within ALS and FTDJulia Remnestål, Royal Institute Of Technology, SwedenD-182Novel plasma proteomic risk markers for malignant ventricular arrhythmias and sudden cardiac deathBen Richards, University Of Leicester, United KingdomD-183Biomarker validation using quantitative LC-MS combined with automated processing of human CSF and blood samples.Anne Roberts, Florey Institute Of Neuroscience And Mental Health, AustraliaD-184Post-translationally modified alpha-1-microglobulin as a plasma biomarker for the early diagnosis of Parkinson’s disease.Blaine Roberts, Florey Inst. Neuroscience, U. of Melbourne, Australia

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

D-185Identification and validation of protein biomarkers for homologous recombination deficiency in breast cancerFrank Rolfs, OncoProteomics Laboratory, Dept. Medical Oncology, Cancer Center Amsterdam, VU University Medical Center, Amsterdam, NetherlandsD-186New tools to improve serodiagnosis of BrucellosisPaola Roncada, Istituto Sperimentale Italiano Lazzaro Spallanzani, ItalyD-187Molecular pathways impairment in Zika virus-infected neural stem cells revealed by proteomic approachLivia Rosa-fernandes, SDU, DenmarkD-188Identification of cartilage endogenous peptides differentially released in the serum of osteoarthritic and healthy patientsCristina Ruiz Romero, Inibic, Spain

D-189Plasma Proteomic Analysis of Intravenous Omega-3 Fatty Acid and Gemcitabine in Advanced Pancreatic AdenocarcinomaFranscois Runau, University Of Leicester, United KingdomD-190Proteomic biomarkers for urothelial carcinoma diagnosis in liquid-based cytology via cross validation with FFPE samplesHan Suk Ryu, Seoul National University Hospital, South KoreaD-191MitoModules as cancer biomarkers: A technique to identify context-based protein biomarkers in mouse liver cancerTatjana Sajic, Ethz, SwitzerlandD-192In vivo SILAC-based proteomics identifies a novel potential target in castration resistant prostate cancerMark Salji, Cruk Beatson Institute, United Kingdom

D-193Whole proteome sequence map of early stage human ovarian follicular fluidAniel Sánchez, Lund University/BMC, SwedenD-194Characterization of proteome of vitreous humor in retinal detachment using different experimental setupsFátima Milhano Santos, University of Beira Interior, PortugalD-195A pathogenic Escherichia coli virulence factor manipulates the host ubiquitin-modified proteome during infectionAndrew Santos, University of British Columbia, CanadaD-196Role of biomarkers in predicting healing of chronic venous ulcers: a proteomic approachLucilene Delazari dos Santos, Unesp, BrazilD-197Deciphering interconnected activities of matrix metalloproteinases in the healing skin wound by targeted degradomicsSimonas Savickas, ETH Zurich, SwitzerlandD-198Discovery and targeted MS-based strategies for the identification of glaucoma-related IgG V domain peptides.Carsten Schmelter, Medical Center Mainz, GermanyD-199A proteomics approach to decipher pneumococcal adaptation during CSF infectionFrank Schmidt, University Medicine Greifswald, GermanyD-200Integration of targeted proteomics into systems-toxicology approach: candidate modified-risk tobacco product assessment using nasal culturesThomas Schneider, Philip Morris International Research & Development, Switzerland

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

D-201Stratifying asthma disease in the U-BIOPRED project: large-scale MSE and TDA to define sub-phenotypesJames Schofield, University Of Southampton, United KingdomD-202Decoding the role of human cardiac stem cells in acute myocardial infarction using proteomic toolsMaria Sebastião, Ibet/itqb, PortugalD-203Combined targeted and shotgun proteomics analysis in saliva for verification of markers of aggressive periodontitisNathalie Selevsek, Eth Zurich, SwitzerlandD-204Proteomic analysis of serum from patient with alcoholic pancreatitis to compare disease with treated statusAeEun Seok, Eulji University, South KoreaD-205The nipple aspirate fluid in health and diseaseSadr-ul Shaheed, University Of Bradford Uk, United KingdomD-206Identification of non-invasive urinary novel biomarkers in urothelial carcinoma of bladder: a Proteomic approachAlpana Sharma, Aiims, New Delhi, IndiaD-207Early-stage blood-based proteomic diagnosis of colorectal cancerSamridhi Sharma, Macquarie University, AustraliaD-208Temporal quantitative phosphoproteomics of ADP stimulation reveals novel central nodes in platelet activation and inhibitionAlbert Sickmann, ISAS, GermanyD-209Proteomics evidence for commonality in altered energy and apoptotic pathways in Alzheimer’s Disease and SchizophreniaNikhat Ahmed, Siddiqui, Barrett Hodgson University, PakhistanD-210Impact of obesity-induced diet on mice brain phospho-proteomeValentina Siino, Lund University, Sweden

D-211Identification of protein targets in cerebral endothelial cells for brain arteriovenous malformation (AVMs) molecular therapiesMargaret Simonian, UCLA, United StatesD-212Quantitative phosphoproteomic profiling to identify new drug targets to treat chronic obstructive pulmonary diseaseDavid Skerrett-Byrne, University Of Newcastle, AustraliaD-213Multiple myeloma associated bone marrow fibroblasts characterized by multi-omics analyses including proteomics, metabolomics and eicosadomicsAstrid Slany, University Of Vienna, Department of Analytical Chemistry, AustriaD-214Ultrasensitive Glycoproteomics pairing LP-IEF with UPLC-MSE to identify site-specific N-Glycosylation changes in Gastric AdenocarcinomaJosh Smith, NIBRT, IrelandD-215A quantitative analytical method using multiple reaction monitoring-mass spectrometry for early diagnosis of hepatocellular carcinomaAreum Sohn, Seoul National university, Korea, Republic of

D-216Optimization of quantitative proteomic analysis of clots generated from plasma of patients with venous thromboembolismAneta Stachowicz, Jagiellonian University Medical College, PolandD-217Pediatric inflammatory bowel disease characterization by proteomics of pre- and post-therapy colon biopsiesAmanda Starr, University Of Ottawa, CanadaD-218Protein biomarkers of metastatic propensity in prostate cancerPascal Steffen, University Medical Center Hamburg-Eppendorf, Germany

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

D-219Development of an apoE-isoform specific PRM assay aiming early prediction of Alzheimer’s disease.Christoph Stingl, Erasmus Medical Center Rotterdam, NetherlandsD-220Comparing the CSF proteome of neuromyelitis optica patients to multiple sclerosis patients and control subjectsMarcel Stoop, Erasmus MC, NetherlandsD-221Quantitative proteomics reveals a crucial role of the allergen context during activation of dendritic cellsLisa Strasser, University Of Salzburg, AustriaD-222MHC peptide ligands from influenza virus differ in their kinetics of presentationTheo Sturm, Biomolecular Mass Spectrometry and Proteomics, Utrecht University, NetherlandsD-223Identification of urinary biomarkers for metastatic colorectal cancerYulin, Sun, State Key Laboratory of Molecular Oncology, National Cancer Center/cancer Hospital, Chinese Academy Of Medical Sciences, ChinaD-224Assessment of the activation of macrophages by quantitative secretome analysisMaciej Suski, Jagiellonian University Medical College, PolandD-225Investigation of 5-fluorouracil resistance in colorectal cancerChris Sutton, University Of Bradford, United KingdomD-226Comprehensive high-throughput analysis of IgA1 O-glycoforms by a sequential deglycosylation protocolKazuo Takahashi, Fujita Health University School of Medicine, JapanD-227Role of α2,6-Sialylation in inhibiting adipogenesisNaoyuki Taniguchi, Riken, Japan

D-228Innovative mass spectrometry to assess the clinical value of proinsulin as early biomarker for diabetesRoel Tans, Radboudumc, Nijmegen, NetherlandsD-229Reproducible quantitative proteomics of extracellular vesicles released from stimulated brain tumour cellsLorne Taylor, RI-MUHC, CanadaD-230Combatting drug resistance in multiple myelomaCiara Tierney, Maynooth University, IrelandD-231Quantitation of putative colorectal cancer biomarker candidates in serum extracellular vesicles by targeted proteomicsTakeshi Tomonaga, National Institutes of Biomedical Innovation, Health And Nutrition, JapanD-232Proteomic characterization of microneedle-extracted human dermal interstitial fluidBao Tran, Excet Incorporated / Edgwood Chemical Biological Center, United StatesD-233Platelet proteome reveals novel pathways of platelet activation and platelet-mediated immunoregulation in dengue.Monique Trugilho, Fiocruz, BrazilD-234Lacrimal protein biomarkers for thyroid associated orbitopathy (TAO)Natacha Turck, University Of Geneva, SwitzerlandD-235Proteome-wide profiling of exosomes revealed exosome-driven intercellular communications in gastric cancer microenvironment and macroenvironmentKoji Ueda, Japanese Foundation For Cancer Research, JapanD-236Proteomics of rat hippocampus reveals proteins related to operant learningMarcelo Valle de Sousa, University of Brasilia, Brazil

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

D-237Differential excretion of uromodulin peptides indicates early changes in the diabetic kidneyJulie Van, University of Toronto, CanadaD-238PRDX2- redox-oligomeric state in Obstructive Sleep Apnea patients with diabetes mellitusFátima Vaz Rodrigues, Institut Ricardo Jorge, PortugalD-239Apolipoprotein E status determination in human saliva using LC-MRM: In Saliva Veritas?Jerome Vialaret, Montpellier Hospital, FranceD-240Sirtuin 5 is probably a potential functional regulator of amino acid metabolismKe Wang, Institutes of Biomedical Sciences, Fudan University, ChinaD-241New targets for inhibition of the PDL1 – PD1 immune checkpointJames Williamson, University Of Cambridge, United KingdomD-242Towards a fit-for-purpose selection of sample preparation strategies for mass spectrometry-based proteomicsJustina Clarinda Wolters, University Medical Center Groningen, NetherlandsD-243Quantitative evaluation towards the Glutathione S-transferases in human plasma using affinity coupling with LC-MS/MSFeng Xian, BGI-shenzhen, ChinaD-244Saliva-specific differential protein signatures for non-invasive detection of cervical carcinomaSavita Yadav, AIIMS, IndiaD-245In situ characterization of infiltrated immune cells of murine EAE by MALDI imaging mass spectrometryHiroki Yamashita, Doshisha University, Japan

D-246PhD abstract competition winner. Poster will be located by the innovation stageUncovering the molecular underpinnings of NGLY1 disease through personalized proteomics and glycoproteomics profilingChristine Yeh, Stanford University, United StatesD-247A high-throughput quantitatively platform for serum stathmin detection in esophageal cancerLu Yan, Chinese Academy of Medical Sciences and Peking Union Medical College, ChinaD-248Reprogramming of the acute translatome and total proteome underlies oncogene-induced stress adaptabilityHaifeng Zhang, University Of British Columbia, CanadaD-249Identification of differential expression proteins in renal cell carcinoma by label-free quantitative proteomics analysisHaili Zhang, Binzhou Medical Universitydong, China., China

D-250iTRAQ based plasma membrane proteomic study discovered CAPG related to HIV latencyLijun Zhang, Shanghai Public Health Clinical Center, Fudan University, China, ChinaD-251Identification of serum autoantibodies for esophageal squamous cell carcinoma using human proteome microarraysXiaohang Zhao, National Cancer Centre/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, ChinaD-252Abnormal tear proteomic profile in patients with traumatic vegetative stateLei Zhou, Singapore Eye Research Institute, SingaporeD-253Discovering proteome alterations in PARK2-mutated Parkinson’s disease patients.Mara Zilocchi, University Of Insubria, Italy

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

D-254Tissue proteomic alterations of colon adenocarcinomaApurva Atak, Indian Institute Of Technology Bombay, IndiaD-255Identification of biomarkers for Proliferative Diabetic Retinopathy (PDR) in the human vitreous humorKeshava Datta, Yu-iob Center For Systems Biology And Molecular Medicine, Yenepoya University, IndiaD-256Long Noncoding RNA HOTAIR Promotes Hepatocellular Carcinoma Cell Proliferation by regulating opioid growth factor receptorFeng Ge, Institute Of Hydrobiology, Chinese Academy Of Sciences, ChinaD-257Cervical mucus proteome in endometriosisGiuseppe Grande, International Scientific Institute “paul Vi”, ItalyD-258Development of a selected reaction monitoring mass-spectrometry assay to detect TSG-6 in human synovial fluidOliver Gray, University Of Manchester, United KingdomD-259Mutations in HIV GAG peptides and their effect on cellular immune response in Pakistani patientsSaeed Khan, Dow University Of Health Sciences, PakistanD-260Exposure to metals during pregnancy and adverse birth outcomes: mechanistic insights from the MIREC studyPremkumari Kumarathasan, Health Canada, CanadaD-261Identification of proteomic biomarkers of arsenic toxicity and evaluation of dietary curcumin supplementation for mitigationBimal Mohanty, Icar-Central Inland Fisheries Research Institute, India

D-262Identification of candidate serum biomarkers of pediatric Growth Hormone deficiency using SWATH-MS and feature selectionIgnacio Ortea, Imibic, SpainD-263Secretome analysis of U937 DC-SIGN cell line after dengue infectionVictoria Pando-robles, Instituto Nacional De Salud Publica, MexicoD-264Comparative proteomic study of CD34 hematopoietic stem cells from HbE/beta thalassemiaSaranyoo Ponnikorn, Chulabhorn International College Of Medicine, Thammasat University, ThailandD-265Detection of novel types of protein carbonylations in human plasma.Adelina Rogowska-Wrzesinska, University Of Southern Denmark, DenmarkD-266Proteome Profiles of Malignant and Non-malignant Human ColonSaira Saleem, Shaukat Khanum Memorial Cancer Hospital And Research Centre, PakistanD-267Shedding new light on Spinal Cord injuryMichel Salzet, Laboratoire Prism, U1192 Inserm, France

D-268Integration of “omics” strategies for the elucidation of molecular mechanisms underlying Brugada SyndromeDomenica Scumaci, Magna Graecia University Of Catanzaro, ItalyD-269Airway proteome signature associated with second-hand smoke exposureSofia Sentieiro, Insa Lisbon, PortugalD-270Aggregation as a consequence of glycation: insight into the pathogenesis of arthritis.Anas Shamsi, Aligarh Muslim University, India

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

D-271Global Proteomics of Tauopathy Brains to Identify Tauopathy-differentiating Disease PathwaysHendrik Wesseling, Boston Children’s Hospital/ Harvard Medical School, United StatesD-272Proteomic Approaches to Identify the Mechanism of rapid progression of Alzheimer’s DiseaseSaima Zafar, Clinical Dementia Center And Dzne, University Medical Center Goettingen (umg), Goettingen, Germany

Precision & Personalised Proteomics

E-001Contribution of combined limited proteolysis and LC-MS/MS to emerin self-assembly characterizationBeatrice Alpha-bazin, French Alternative Energies and Atomic Energy Commission, France

E-002Breast cancer classification based on proteotypes obtained by SWATH-MSPavel Bouchal, Masaryk University, Faculty of Science, Czech RepublicE-003Development of an enzyme-assisted targeted glycopeptide quantification method for early detection of liver diseasesChen-Chun Chen, Academia Sinica, TaiwanE-004Proteomic analysis of single cell clusters using laser capture microdissectionSimon Davis, University Of Oxford, United KingdomE-005Systems pharmacology and quantitative proteomics for developing targeted triple therapyH. Alexander Ebhardt, University College Dublin / Systems Biology Ireland, IrelandE-006Towards comprehensive signaling pathway monitoring using advanced PRM methodsSebastien Gallien, Thermo Fisher Scientific, France

E-007There are still proteins in rat urine after 7-day starvationYouhe Gao, Beijing Normal University, ChinaE-008Early protein biomarker discovery in urine of Walker 256 subcutaneous rat modelYouhe Gao, Beijing Normal University, ChinaE-009The discovery of kidney injury-related protein biomarkers associated with first-line antiretroviral treatment in South AfricaIreshyn Govender, Council for Scientific and Industrial Research South Africa, South AfricaE-010Use of Andrew liquid handling robot for protein digestion of serum for quantitative proteomic workflowsDarren Greene, Ucd, IrelandE-011Membrane proteome profiling of peripheral immune cells in non-small-cell lung cancer patients with PEM/CIS chemotherapyChia-Li Han, Master Program For Clinical Pharmacogenomics And Pharmacoproteomics, Taipei Medical University, TaiwanE-012Identification of a novel therapeutic target for tongue cancer by antibody-based proteomicsOnidani Kaoru, National Cancer Center Research Institute Division of Early Detection for Cancer, JapanE-013Novel LC-MS assay unveils an acute decrease in serum sRAGE levels after cigarette smokingFrank Klont, University of Groningen, NetherlandsE-014Profiling Of proteoforms in human tears using chip-based capillary electrophoresis coupled to mass spectrometryDaniel Lopez-ferrer, Thermo Fisher Scientific, United StatesE-015Proteomic identification of vitreous biomarkers for retinal degenerationVinit Mahajan, University Of Iowa, United States

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

E-016Towards an understanding of neoantigen presentation by Human Leukocyte Antigen (HLA) class IGeert Mommen, Immunocore, United KingdomE-017Individualised proteogenomics in analysis of single amino acid variants in cancerNicolas Nalpas, Proteom Centrum Tübingen, GermanyE-018Revolutionary proteome profiling and quantitation without compromising speed, sensitivity, and selectivitySega NDIAYE, Thermo Fisher Scientific, FranceE-019Absolute quantification of a membrane-localized chemosensory protein networkAnsgar Poetsch, Plymouth University, United KingdomE-020Phenotyping of rheumatoid arthritis patients by citrulline specific immunome protein arraysThomas B.G. Poulsen, Aalborg University, DenmarkE-021Co-stimulatory inhibition with abatacept and the effect on the complement system in rheumatoid arthritisAllan Stensballe, Aalborg University, DenmarkE-022Identification of functional protein biomarkers from cancer patient serum with PEP technologyXing Wang, Array Bridge Inc, United StatesE-023Strategies for identification of organ-specific biomarkers of exposure to ionizing radiationJulian Whitelegge, Ucla, United StatesE-024In-depth quantitative proteomic profiling of rat heartJuanjuan Xie, Institute Of Biomedical Science, Fudan University, China

E-025Impact of AssayMap Bravo Liquid handling Platform on high throughput protein digestion for quantitative proteomicsAlison Doody, Ucd, IrelandE-026Comprehensive tissue proteomic analysis of human gliomasKishore Gollapalli, Indian Institute Of Technology Bombay, India

Human Proteome Project

F-001Profiling biochemical individuality: human personal omics profiling (hPOP)Sara Ahadi, Stanford, United StatesF-002Towards the standardization of mitochondrial proteomics: the Italian mt-HPP initiativeTiziana Alberio, University of Insubria, ItalyF-003Sensitivity, specificity and accuracy of the targeted and shotgun mass-spectrometry approachesAlexander Archakov, Institute Of Biomedical Chemistry, Russian FederationF-004Discovery of new proteins and modifications with community-scale proteomics big dataNuno Bandeira, University of California, San Diego, United StatesF-005The iMOP initiative and its roles in a biology and disease driven human proteome projectEmoke Bendixen, AARHUS - Department of Molecular Biology and Genetics, DenmarkF-006Development of an analytic interface for multiple peptide library search and label-free comparative proteomic analysisJin-young Cho, Yonsei University, South KoreaF-007Evaluation of NCI-7 cell line panel as new CPTAC CompRef materialDavid Clark, The Johns Hopkins University, United States

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

F-008Zika virus signature in fetal brains with microcephalyGilberto Domont, Universidade Federal do Rio de Janeiro, BrazilF-009comprehensive bioinformatics workflow for analysis and identification of human missing proteinsAmr Elguoshy, Biofluid And Biomarker Center- Niigata Unversity, JapanF-010Terminal Amine Isotopic Labeling of Substrates (TAILS) approach to study mitochondrial proteases in Parkinson’s diseaseMauro Fasano, University Of Insubria, ItalyF-011CSF analysis for protein biomarker identification and validation in patients with CNS LymphomaManuel Fuentes, Cancer Research Center, SpainF-012Impairment of Protein Mitochondrial Quality Control (PMQC) in Amyotrophic Lateral SclerosisViviana Greco, Fondazione Santa Lucia IRCCS, ItalyF-013Native peptidomics: Workflow of discovering biomarker for disease from human body fluidsYoshitoshi Hirao, Niigata University, JapanF-014Taking up the “neXt50 challenge” using human spermLydie Lane, Sib-swiss Institute Of Bioinformatics, SwitzerlandF-015Determination of the RNA / protein ratio in human cellsGianluca Maddalo, Kth, SwedenF-017MissingProteinPedia (MPP), a platform to uncover the human ‘Missing proteins’ (www.missingproteins.org)Abidali Mohamedali, Macquarie University, Australia

F-018Detection of low abundant HPV16-derived HLA-A2 epitopes on the tumor cell surface by mass spectrometryNitya Mohan, Deutsches Krebsforschungzentrum, GermanyF-019Protocol optimization for deep analysis of Major Histocompatibility Complex (MHC) ImmunopeptidomesAnnalisa Nicastri, University Of Oxford, United KingdomF-020Protein array enabled profiling of autoantibody repertoires in ALS, ALS-FTD and FTDPeter Nilsson, SciLifeLab, KTH - Royal Institute of Technology, SwedenF-021Insights into human brain development; a proteomics perspectiveSureyya Ozcan, University Of Cambridge, United KingdomF-022The human proteome discovery via diseased testis tissues in search of missing proteinsHyoung Min Park, Seoul National University, South KoreaF-023Peptidomics characterization of allergenic and non allergenic tropomyosin orthologsCristian Piras, University of Milan, Department of Veterinary Medicine DIMEVET, ItalyF-024Digging more missing proteins using a depletion approach with ProteoMinerYan Ren, Bgi-shenzhen, ChinaF-025Effects of amino acid supplementation on the performance of gilthead seabream using 2D-DIGEDenise Schrama, Centre Of Marine Sciences, PortugalF-026Enhanced proteome coverage of MCF7 cells using an integrative search engine approachVictor Segura, Fima, Spain

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16th Human Proteome Organisation World Congress | Integrated Proteomics for Healthcare Systems

F-027A method for selecting a representative protein of the highest protein evidence from non-unique proteins.Hiromasa Tojo, Translational Medicine Informatics, St. Marianna University School Of Medicine, JapanF-028Regional variation and novel pathogenesis in the human Alzheimer’s disease brainRichard Unwin, The University Of Manchester, United KingdomF-029Multi-protease strategy identifies more membrane-associated missing proteins in human testis tissuePing Xu, Beijing Proteome Research Center, ChinaF-030Proteomics of Urine AQP2-bearing ExosomeKeiko Yamamoto, Biofluid Biomarker Center, Niigata University, Japan

F-031Next-generation Proteomic Pipeline (NextPP) for Chromosome-based Proteomic Research Using GENCODE and neXtProt DatabasesJong Shin Yoo, Korea Basic Science Institute, South KoreaF-032Quantitation of phosphorylated myelin basic protein in brain tumor tissues using pSRMMaria Zavialova, Institute of biomedical chemistry, Russian FederationF-033Targeted quantitative screening of Chromosome 18 encoded proteome in plasma samples of astronaut candidatesVictor Zgoda, Institute Of Biomedical Chemistry, Russian Federation

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