priority research and joint programming needs in the

This project has received funding from the Euratom research and training programme 2014-2018 under grant agreement No 662287.

Priority Research and Joint Programming Needs

in the Perspective of European Integration

Nathalie Impens

CONCERT WP3 leader


CONCERT European Joint Programme for the Integration of Radiation Protection Research

WP8 Ethics

WP9 Research

projects

selected

through

CONCERT

open calls


Call topics: alignment of European and national research

• European platforms in radiation protection research

• National Programme Owners and Programme Managers

• Needs to implement Basic Safety Standards


Transnational call for proposals for “Radiation Protection Research in Europe”

The aims of the call are:

To support transnational research projects that combine innovative approaches in the field of radiation protection in line with the research priorities of CONCERT

To actively integrate E&T activities and collaboration with universities in multidisciplinary research projects

To make optimal use of research infrastructures

Project proposals will address multidisciplinary and transnational research. The project proposals must fall within one of the following topics. They may answer one or more sub-topics within one of the topics when appropriate


Process towards definition of Call topics

Alignment of European

and

National research priorities


SRA SRA SRA SRA SRA

Social sciences and humanities

WP2 updating SRA and research priority statements

SRA

http://www.google.be/url?sa=i&rct=j&q=eurados&source=images&cd=&cad=rja&docid=_UuaeQr3VSo57M&tbnid=lsBnvY4_BPp6uM:&ved=0CAUQjRw&url=http://www.medicalconsult.pt/en/research-and-development/30/partnerships&ei=13BRUb36OubE0QXi8YHwCg&bvm=bv.44158598,d.d2k&psig=AFQjCNEn7OZnStPeoTt_jqqDNxtUs-8j2Q&ust=1364378198296221

http://www.google.be/url?sa=i&rct=j&q=EC+FP+DOREMI&source=images&cd=&cad=rja&docid=7aQKJvroT4FT6M&tbnid=dmfDJkU-5qUX2M:&ved=0CAUQjRw&url=http://www.doremi-noe.net/about_doremi.html&ei=zHdRUc-PF8rL0QXXqoCADQ&bvm=bv.44158598,d.d2k&psig=AFQjCNGq4wQL_PJWcj0GmOGUggyObKB8sg&ust=1364379978700488


• Mission: MELODI is an European platform dedicated to low dose radiation risk research

• 40 organisations from 19 countries

EPIdemiological study to quantify risks for paediatric Computerised Tomography and to optimise doses (2011-2015), WP leader

Cognitive and cEREBrovascular Effects Induced by Low Dose Ionizing RADiation (2011-2015), co-ordinator

OPEn project for Radiation Protection ReseArch (2013-2017), task leader

Integrating low-dose research (2010-2015), WP leader

European Joint Programme for the Integration of Radiation Protection Research (2015-2020), WP leader and task leader

Multidisciplinary European LOw Dose Initiative


MELODI Priorities 2016

1. To understand the potential impact of individual susceptibility on radiation-induced health effects (Rank 1: high priority)

2. To identify, develop and validate biomarkers for exposure, early and late effects for cancer or/and non-cancer diseases (Rank 2: medium priority)

3. To understand the health effects of inhomogeneous dose distributions, radiation quality and internal emitters (Rank 2: medium priority)

4. To explore and define the role of epigenetic modifications in radiation-induced health effects (Rank 2: medium priority)

5. To explore the roles of specific target cells for radiation-induced late developing health effects (Rank 2: medium priority)

6. To explore the shape of the dose-response relationship for radiation-induced health effects (Rank 3: low priority)


• Mission: Promote European research, development & cooperation in dosimetry

• 64 voting members

Establishment of TECHnical RECommendations for monitoring individuals for occupational intakes of radionuclides (2014-2016), WP leader

EUropean RAdiation DOSimetry group




EURADOS Priorities 2016

1. To quantify correlation between track structure and radiation damage

2. To improve neutron dosimetry techniques 3. To quantify doses after accidental internal contamination 4. To develop accurate and on-line personal dosimetry for

workers 5. To improve the measurement and combination of out-of-

field radiotherapy and imaging doses in photon and particle radiotherapy, for input to epidemiological studies

6. To improve dosimetry in modern external beam radiotherapy



• Mission: Improve effectiveness of current European, national

and local approaches for preparedness concerning nuclear or radiological emergency response and recovery


Innovative integrated tools and Platforms for Radiological Emergency Preparedness and post-Accident Response in

Europe

European platform on preparedness for nuclear and radiological emergency response and recovery


NERIS priorities 2016

1. Assessment of and communication of uncertainties

2. Robust decision-making

3. Countermeasure strategy preparedness

4. Atmospheric dispersion modelling

5. Local radio-ecological models

6. Monitoring strategies


• Mission: integrate research and infrastructure to maintain and enhance radioecological competences and addresses scientific and educational challenges in assessing the impact of radioactive substances on humans and environment


STrategy for Allied Radioecology (NoE)

COordination and iMplementation of a pan-Europe instrumenT for radioecology

European Radiology Alliance - ALLIANCE


ALLIANCE Priorities 2016

1. Biomarkers of exposure and effects in living organisms as operational outcomes of a mechanistic understanding of intra- and inter-species variation of radiosensitivity under chronic low dose exposure situations, with a focus on the added value for both human and non-human radiological protection

2. Environmental availability and impact of radionuclides in terrestrial, freshwater and marine ecosystems (including human food chain) and their interactions with atmosphere, incorporating physical, chemical and/or biological processes. Validated process-based model parameterisation, characterisation of variability and uncertainty, and guidance for fit-for-purpose models

3. Development of models/tools, and datasets for their calibration and validation and guidance to select and evaluate the effectiveness of different remediation strategies in long-lasting exposure situations (e.g. nuclear accidents and/or NORM/TeNORM)

4. Multiple stressors and modulation of radiation effects in living organisms


Vision • To lead the European research activities in medical RP and to assume an

umbrella function for the harmonisation of practice to advance the European RP safety culture in medicine

Composition: represents a consortium of associations involved in application of ionising radiation in medicine:

• European Association of Nuclear Medicine (EANM)

• European Federation of Organisations for Medical Physics (EFOMP)

• European Federation of Radiographer Societies (EFRS)

• European Society of Radiology (ESR)

• European Society for Radiotherapy and Oncology (ESTRO)

SRA • First version September 2016

EURopean Alliance for MEDical Radiation Protection Research


EURAMED Priorities 2016

1. Patient-tailored diagnosis and treatment: full exploitation and improvement of technology and techniques with clinical and dose structured reporting

2. Individual patient-related radiation sensitivity and early biomarkers of response and morbidity


• SRA and platform under development • Scope: broader than Radiation Protection

Social Sciences and Humanities

Enhancing educAtion, traininG and communication processes for informed behaviours and decision-making reLatEd to ionising radiation risks

Building a PLATform for ENhanced SOcietal research related to nuclear energy in Central and Eastern Europe


Social Siences and Humanities Priority

Models, tools and rationales for stakeholder engagement and informed decision-making in radiation protection research, policy and practice for situations involving exposure to ionizing radiation


Input from POMs

Selection by RP

platforms (SRA)

Consultation of

CONCERT MB,

23 September 2016;

Outcome 1st call

17 November 2016

Call priorities + call conditions

Approval by MB,

December 2016

Submission to

WP4

SRA

priorities

from RP

platforms

(WP2)

Medical

SRA (WP2)

Basic Safety

Standards

(WP2)

Social

sciences &

humanities

(WP2)

Stake-

holders

(WP5)

Integrative

activities for

calls

(WP6 &

WP7)

Open consultation

18 November 2016

2nd Call topics Working procedure


This process has lead to the following topics for the CONCERT - 2nd Call

2 Priority Topics with subtopics described in the call text

Topic 1 - Understanding human health effects from ionising radiation and improving dosimetry

I. Improvement of health risk assessment associated with low dose/dose rate radiation.

II. Improvement of occupational dosimetry.

III. Patient-tailored diagnosis and treatment: full exploitation and improvement of technology and techniques with clinical and dose structured reporting.

Topic 2 - Radioecology, emergency and social sciences and humanities I. Biomarkers of exposure and effects in living organisms, as operational outcomes

of a mechanistic understanding of intra- and inter-species variation of radiosensitivity under chronic low dose exposure situations.

II. Countermeasure strategies preparedness for emergency and recovery situations.

III. Models, tools and rationales for stakeholder engagement and informed decision-making in radiation protection research, policy and practice for situations involving exposures to ionising radiations.


Full Call topic texts available at CONCERT website

http://www.concert-h2020.eu/en/Calls/Transnational_Call_2017






RECOMMENDATIONS

Impact and collaboration

Proposals must clearly demonstrate the potential impact on radiation protection in Europe as well as the added value of transnational collaboration: sharing of resources (models, registries, diagnoses, etc.), harmonisation of data, sharing of specific know-how and/or innovative technologies.

The individual project partners of the joint applications should be complementary and the proposed work should contain novel, innovative, ambitious ideas and their potential application to the end user.

Education and Training

Education and training is a part of all activities within CONCERT. Proposals should include a plan for integration of education and training into the research programme, with a description of the proposed activities. The proposal should also give details of collaboration or involvement with academic departments, and of intended PhD thesis work, MSc project work, teaching seminars, ad hoc courses on the topics of the proposal, etc., where possible.


RECOMMENDATIONS

Quality assurance, Open Access and Infrastructures

Proposals must clearly identify the infrastructures required to perform the research and belonging to the following three categories:

1. irradiation platforms and contamination sites

2. databases, sample banks and cohorts,

3. analytical platforms (including ‘omics ones), models and tools.

The applicant to the call should document the expertise in using such infrastructures.

Proposals must demonstrate the appropriateness of the approaches, techniques or infrastructures that they plan to use, in terms of feasibility, reliability, quality assurance and traceability of the results to be generated in relation to the objectives of the project (e.g. reliable dose quantification, common standards for omics).


RECOMMENDATIONS

A Data Management Plan (DMP), and if applicable, a Sample Management Plan (SMP), should be included in the proposal (http://ec.europa.eu/research/participants/data/ref/h2020/grants_manual/hi/oa_pilot/h2020-hi-oa-data-mgt_en.pdf)

Social Sciences and Humanities

Social Sciences and Humanities (SSH) are given an enhanced role as a cross-cutting issue. Even if proposals do not belong to the SSH relevant sub-topic, they may contain contributions from the SSH disciplines.

http://ec.europa.eu/research/participants/data/ref/h2020/grants_manual/hi/oa_pilot/h2020-hi-oa-data-mgt_en.pdf



















Timetable

Pre-announcement: 18 January 2017

Publication of the joint call: 1 March 2017

Deadline for submission of proposals: 2 May 2017

More information : http://www.concert-h2020.eu/en/Calls/Transnational_Call_2017

January 2017

March 2017

May 2017







Funding

2nd Call – €6.98 m total budget 80% TOPIC 1 up to 3 projects 20% TOPIC 2 up to 2 projects

More information : http://www.concert-h2020.eu/en/Calls/Transnational_Call_2017







Acknowledgements

Thank you for your attention and interest in CONCERT calls

aiming at joint radiation protection research!

priority research and joint programming needs in the

Documents