product catalogue...immunodiagnostic assays for the global laboratory market. with extensive...

Specialist Immunologicals

Specialist Immunologicals

Product CatalogueProducts for IVD Manufacturers

Antibodies

Antigens

Clinical Specimens

Disease State Sera

Manufacturing Reagents

Quality Assurance

Our manufacturing site has quality systems approved to both ISO9001 and ISO13485:2003 certification. These, together with strict adherence to rigorous internal quality control procedures, ensure customers can be confident in the quality of Binding Site products.

Reducing our Impact on the Environment

Binding Site’s environmental policy outlines our commitment to limit the overall impact our processes have on the environment. The new 2011 head office was built with a focus on reduced energy and water consumption, has provisions for rainwater harvesting and meets strict carbon emission restrictions. All staff are trained on our Reduce, Reuse & Recycle policy.

Binding Site is a Specialist Protein company committed to the research, development, manufacture and distribution of innovative immunodiagnostic assays for the global laboratory market. With extensive expertise in antibody specificity technology, Binding Site gives clinicians and laboratory staff the tools to significantly improve diagnosis and management of patients across a range of cancers and immune system disorders.

Binding Site Offices

The headquarters of The Binding Site Group Ltd is located in Birmingham, UK and employs over 400 people.

In addition to research activities, the main site houses product development and manufacturing along with global distribution, marketing and administrative functions. Direct sales and product support to customers in the UK are based here together with sales and technical support provided to our distributor network in 81 countries .

Direct Binding Site sales and support organisations are also based in: San Diego, California for USA & Canada Schwetzingen, near Heidelberg for Germany, Austria & Switzerland Grenoble for France & French speaking distributor markets Barcelona for Spain & Portugal Prague for Czech Republic & Slovak Republic Antwerp for Belgium, Netherlands & Luxembourg Bergamo, near Milan for Italy São Paulo for Latin America

Binding Site

TABLE OF CONTENTS PAGE INTRODUCTION 1

ANTIBODIES 2 Human Immunoglobulins 2� Human Complement 3 � Human Acute Phase Proteins 3� Human Coagulation Proteins 4� Other Human Proteins 4� FITC Conjugated Human Immunoglobulin Antibodies 5� FITC Conjugated Human Complement/Coagulation Protein Antibodies 5� HRP Conjugated Human Immunoglobulins 6� HRP Conjugated Human Protein Antibodies 6� HRP Conjugated Monoclonal Antibodies 6� Animal Proteins 7 FITC Conjugated Antibodies to Animal Proteins 7 HRP Conjugated Antibodies to Animal Proteins 7 ANTIGENS 8 � Human Purifi ed Myeloma Antigens 8 � Other Human Native Antigens 8 Specialist Bulk Antigens 9

CLINICAL SPECIMENS (USA/Germany only) 10

DISEASE STATE SERA 11 � Human Myeloma 11� Human Thyroid Autoantibodies 11� Human Liver/Kidney Autoantibodies 11� Human Muscle Autoantibodies 11� Human Intestinal/Pancreatic Autoantibodies 12 Human Skin Autoantibodies 12� Human ENAs 12 � Human ANA/dsDNA Autoantibodies 12� Human ANCAs 12� Human Phospholipid Antibodies 13� Human Neurological Autoantibodies 13� Infectious Disease/Viral Positive Sera 13� Additional Disease State Sera 13

MANUFACTURING REAGENTS 14 � Bulk Volume Antibodies to Special Proteins 14 Human Rheumatoid Factor (RF)/IgG Absorbent 15

Introduction to Immunologicalsfrom Binding Site

As a manufacturer of a wide range of innovative in vitro diagnostic products, Binding Site understands the necessity for high quality raw materials and components. With a proven track record for over a quarter of a century, our expertise in immunisation and processing techniques has led to our international recognition as a key supplier of antibodies, antigens, bulk antisera, clinical specimens and diagnostic reagents.

Our fl exibility of scale from small R&D quantities to larger lots allow us to support your project whatever its size. Key elements for success lie within the way we work and the quality systems that are in place.

• Our commitment to continuous improvement allows us to enhance the quality of our product and service offering

• Working closely with researchers to ensure a focused and timely delivery of your product

• We are accredited to both ISO9001 and ISO13485:2003 and manufacture to GMP standards. Our internal quality systems ensure high standards, consistency, and reliability of product supply.

From initial product concept through to launch, we pledge to you excellence in quality, attention to detail, and the highest in customer service.

Whatever your requirements, we would welcome hearing from you and we look forward to working with you now and in the future.

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Binding Site offers a comprehensive range of antibodies focusing on human serum proteins including their subclasses. Affi nity purifi ed, IgG fraction and conjugations to Fluorescein-Isothiocyanate (FITC) and Horseradish Peroxidase (HRP) are routinely available. Additional custom formats can be made available on request.

Affi nity purifi ed antibodies (product codes starting A) are purifi ed against an immobilised antigen. In some instances, solid phase absorption is also utilised to reduce inter-species cross reactivity. IgG fraction antibodies (product codes starting P) are IgG fractions of sheep sera.

Human Immunoglobulins

A wide range of human immunoglobulins are available for use in immunoassay testing methodologies. In many instances the volumes of product are unspecifi ed to allow maximum customer choice and fl exibility.

Sheep Polyclonal Antibodies

Antibodies An

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PRODUCTDESCRIPTION FORMAT VOLUME CATALOGUE

NUMBERIgA IFE Grade Antisera Customer Specifi ed FX010

IgA Affi nity Purifi ed Customer Specifi ed AU010.X

IgA IgG Fraction 1mL PC010IgA IgG Fraction Customer Specifi ed PC010.XIgE IFE Grade Antisera Customer Specifi ed FX014IgE IgG Fraction Customer Specifi ed PC014.XIgG IFE Grade Antisera Customer Specifi ed FX004IgG Whole Serum Grade Customer Specifi ed PE004.XIgG Affi nity Purifi ed 2mg AU004IgG Affi nity Purifi ed Customer Specifi ed AU004.XIgG IgG Fraction 1mL PC004IgG IgG Fraction Customer Specifi ed PC004.XIgG (H & L) IgG Fraction 1mL PC003IgG (H & L) IgG Fraction Customer Specifi ed PC003.XIgG (H & L) Monkey Adsorbed Affi nity Purifi ed 1mL AU003.MIgG (Fd) IgG Fraction 1mL PC075IgG (Fd) IgG Fraction Customer Specifi ed PC075.XIgG1 Affi nity Purifi ed 0.5mg AU006IgG1 Affi nity Purifi ed Customer Specifi ed AU006.XIgG2 Affi nity Purifi ed 0.5mg AU007IgG2 Affi nity Purifi ed Customer Specifi ed AU007.XIgG3 Affi nity Purifi ed 0.5mg AU008IgG3 Affi nity Purifi ed Customer Specifi ed AU008.XIgG4 Affi nity Purifi ed 0.5mg AU009IgG4 Affi nity Purifi ed Customer Specifi ed AU009.X

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NUMBERHuman IgG4 MAb Clone HP6025 IgG Fraction Customer Specified MC011.X

Human IgG4 MAb Clone HP6025 IgG Fraction 0.2mg MC011

Monoclonal Antibodies

Human Complement - Sheep Polyclonal Antibodies


NUMBERC1q IgG Fraction 1mL PC020C1q IgG Fraction Customer Specified PC020.XC3c IgG Fraction Customer Specified PC023.XC3d IgG Fraction Customer Specified PC024.XC3d Whole Serum Grade Customer Specified PE024.XC4 IgG Fraction Customer Specified PC025.XC4 Binding Protein IgG Fraction 1mL PC026C4 Binding Protein IgG Fraction Customer Specified PC026.XC5 IgG Fraction Customer Specified PC027.XC8 IgG Fraction Customer Specified PC089.XFactor H [ß1H] IgG Fraction 1mL PC030Factor H [ß1H] IgG Fraction Customer Specified PC030.XFactor I [KAF/C3b Inactivator] IgG Fraction 1mL PC031Factor I [KAF/C3b Inactivator] IgG Fraction Customer Specified PC031.X


NUMBERIgM IFE Grade Antisera Customer Specified FX012IgM IgG Fraction Customer Specified PC012.XKappa Light Chain Affinity Purified 2mg AU015Kappa Light Chain Affinity Purified Customer Specified AU015.XKappa Light Chain IFE Grade Antisera Customer Specified FX015Lambda Light Chain Affinity Purified 2mg AU017Lambda Light Chain Affinity Purified Customer Specified AU017.XLambda Light Chain IFE Grade Antisera Customer Specified FX017

Sheep Polyclonal Antibodies - cont.

Human Acute Phase Proteins - Sheep Polyclonal Antibodies


NUMBERAntithrombin III IgG Fraction 1mL PC040Antithrombin III IgG Fraction Customer Specified PC040.Xß2 Microglobulin IgG Fraction Customer Specified PC043.XFibrinogen IgG Fraction Customer Specified PC056.XHaptoglobulin IgG Fraction 1mL PC058Haptoglobulin IgG Fraction Customer Specified PC058.X

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Human Coagulation Proteins - Sheep Polyclonal Antibodies


NUMBERAlpha Trypsin Inhibitor IgG Fraction Customer Specified PC060.XAntithrombin III IgG Fraction 1mL PC040Antithrombin III IgG Fraction Customer Specified PC040.XElastase IgG Fraction Customer Specified PC052.XFibrinogen IgG Fraction Customer Specified PC056.XFibrinogen Whole Serum Grade Customer Specified PE056.XFibronectin IgG Fraction Customer Specified PC057.XPlasminogen IgG Fraction Customer Specified PC065.XProthrombin IgG Fraction Customer Specified PC067.Xvon Willebrand Factor IgG Fraction 1mL PC054von Willebrand Factor IgG Fraction Customer Specified PC054.X

Other Human Proteins


NUMBERAlbumin IgG Fraction 1mL PC032Albumin IgG Fraction Customer Specified PC032.Xα2 HS Glycoprotein IgG Fraction Customer Specified PC124.XCarbonic Anhydrase 2 IgG Fraction Customer Specified PC076.XLD Isoenzyme V IgG Fraction 1mL PC154LD Isoenzyme V IgG Fraction Customer Specified PC154.XPrealbumin IgG Fraction Customer Specified PC066.XSuperoxide Dimutase (Cu/Zn) IgG Fraction 1mL PC077Superoxide Dimutase (Cu/Zn) IgG Fraction Customer Specified PC077.XTamm Horsfall Protein (Uromucoid) IgG Fraction 1mL PC071Tamm Horsfall Protein (Uromucoid) IgG Fraction Customer Specified PC071.X

Transferrin IgG Fraction 1mL PC070

Transferrin IgG Fraction Customer Specified PC070.X

Superoxide Dismutase (Mn) IgG Fraction Customer Specified PC096.X

Sheep Polyclonal Antibodies


NUMBERCD23 Clone BU38 IgG Fraction 0.2mg MC112CD23 Clone BU38 IgG Fraction Customer Specified MC112.X

Monoclonal Antibodies

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FITC Conjugated Human Immunoglobulin Antibodies


NUMBERIgA IgG Fraction Customer Specified PF010.XIgA [Monkey Adsorbed] Affinity Purified Customer Specified AF010.M.XIgG [Monkey Adsorbed] Affinity Purified Customer Specified AF004.M.XIgG1 Affinity Purified 0.5mg AF006IgG1 Affinity Purified Customer Specified AF006.XIgGAM (H+L) IgG Fraction Customer Specified PF002.XIgG IgG Fraction Customer Specified PF004.XIgG2 Affinity Purified 0.5mg AF007IgG2 Affinity Purified Customer Specified AF007.XIgG3 Affinity Purified 0.5mg AF008IgG3 Affinity Purified Customer Specified AF008.XIgG4 Affinity Purified 0.5mg AF009IgG4 Affinity Purified Customer Specified AF009.XIgM Affinity Purified Customer Specified AF012.X

IgM IgG Fraction Customer Specified PF012.X

IgG (H+L) Affinity Purified Customer Specified AF003.X

IgG (H+L) [Monkey Adsorbed] Affinity Purified Customer Specified AF003.M.X

Kappa Light Chain Affinity Purified 1mg AF015

Kappa Light Chain Affinity Purified Customer Specified AF015.X

Lambda Light Chain Affinity Purified 1mg AF017

Lambda Light Chain Affinity Purified Customer Specified AF017.X


NUMBERC1q IgG Fraction 1mL PF020C1q IgG Fraction Customer Specified PF020.XC3c IgG Fraction 1mL PF023C3c IgG Fraction Customer Specified PF023.XC4 IgG Fraction Customer Specified PF025.XVon Willebrand Factor IgG Fraction 1mL PF054Von Willebrand Factor IgG Fraction Customer Specified PF054.XFibrinogen IgG Fraction Customer Specified PF056.X

FITC Conjugated Human Complement/Coagulation Protein Antibodies

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NUMBERAlbumin IgG Fraction 1mL PP032Albumin IgG Fraction Customer Specified PP032.Xα1 a-Trypsin IgG Fraction 1mL PP034α1 a-Trypsin IgG Fraction Customer Specified PP034.XTransferrin IgG Fraction 1mL PP070Transferrin IgG Fraction Customer Specified PP070.X


NUMBERIgG4 clone HP6025 IgG Fraction 0.2mg MP011IgG4 clone HP6025 IgG Fraction Customer Specified MP011.X

HRP Conjugated Human Proteins - Sheep Polyclonal Antibodies

HRP Conjugated Human Immunoglobulins - Monoclonal Antibodies

HRP Conjugated Human Immunoglobulins - Sheep Polyclonal Antibodies


NUMBERIgG (H+L) [Monkey Adsorbed] Affinity Purified 1mg AP003.MIgG Affinity Purified 1mg AP004IgG Affinity Purified Customer Specified AP004.XIgG1 Affinity Purified 0.5mg AP006IgG1 Affinity Purified Customer Specified AP006.XIgG2 Affinity Purified 0.5mg AP007IgG2 Affinity Purified Customer Specified AP007.XIgG3 Affinity Purified 0.5mg AP008IgG3 Affinity Purified Customer Specified AP008.XIgG4 Affinity Purified 0.5mg AP009IgG4 Affinity Purified Customer Specified AP009.XIgA Affinity Purified 1mg AP010IgA Affinity Purified Customer Specified AP010.XIgM Affinity Purified 1mg AP012IgM Affinity Purified Customer Specified AP012.XKappa Light Chain Affinity Purified 1mg AP015Kappa Light Chain Affinity Purified Customer Specified AP015.XLambda Light Chain Affinity Purified 1mg AP017Lambda Light Chain Affinity Purified Affinity Purified AP017.X

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NUMBERSheep Anti-Dog IgG (H&L) IgG Fraction Customer Specifi ed PC230.XSheep Anti-Mouse IgG (H&L) Affi nity Purifi ed Customer Specifi ed AU271.XSheep Anti-Mouse α1 Hydroxylase IgG Fraction 1mL PC290Sheep Anti-Mouse α1 Hydroxylase IgG Fraction Customer Specifi ed PC290.XSheep Anti-Rabbit IgG (H&L) Affi nity Purifi ed Customer Specifi ed AU311.XDonkey Anti-Sheep/Goat IgG (H+L) Affi nity Purifi ed 2mg AU360

Donkey Anti-Sheep/Goat IgG (H+L) Affi nity Purifi ed Customer Specifi ed AU360.X


NUMBERDonkey Anti-Sheep/Goat IgG (H+L) IgG Fraction 1mg PF360

Donkey Anti-Sheep/Goat IgG (H+L) IgG Fraction Customer Specifi ed PF360.X

Sheep Anti-Cat IgG (H+L) IgG Fraction 1mL PF210Sheep Anti-Cat IgG (H+L) IgG Fraction Customer Specifi ed PF210.XSheep Anti-Dog IgG (H+L) IgG Fraction 1mL PF230Sheep Anti-Dog IgG (H+L) IgG Fraction Customer Specifi ed PF230.XSheep Anti-Rabbit IgG (H+L) Affi nity Purifi ed Customer Specifi ed AF311.X


NUMBERSheep Anti-Mouse IgG (H+L) Affi nity Purifi ed 1mg AP271Sheep Anti-Mouse IgG (H+L) Affi nity Purifi ed Customer Specifi ed AP271.XSheep Anti-Mouse IgG Affi nity Purifi ed 1mg AP272Sheep Anti-Mouse IgG Affi nity Purifi ed Customer Specifi ed AP272.XSheep Anti-Rabbit IgG (H+L) Affi nity Purifi ed 1mg AP311Sheep Anti-Rabbit IgG (H+L) Affi nity Purifi ed Customer Specifi ed AP311.X

Donkey Anti-Sheep/Goat IgG (H+L) Affi nity Purifi ed 1mg AP360

Donkey Anti-Sheep/Goat IgG (H+L) Affi nity Purifi ed Customer Specifi ed AP360.X

Antibodies to Animal Proteins

FITC Conjugated Antibodies to Animal Proteins

HRP Conjugated Antibodies to Animal Proteins

An

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Antigens

PRODUCTDESCRIPTION VOLUME CATALOGUE

NUMBER

Human IgG1 Kappa 1mL BP078

Human IgG1 Kappa Customer Specifi ed BP078.X

Human IgG1 Lambda Customer Specifi ed BP079.X

Human IgG2 Kappa 1ml BP080








Human IgA1 Kappa Customer Specifi ed BP086.X


NUMBER

Human CRP 99% Pure (Ascitic fl uid) Customer Specifi ed BP300.X

Human CRP 80% Pure (Ascitic fl uid) Customer Specifi ed BP301.X

Human HBsAg type ay Customer Specifi ed BP302.X

Human HBsAg type ad Customer Specifi ed BP303.X

Human Prothrombin Antigen Customer Specifi ed BP314.X

Human Prothrombin Antigen - Glycerol Free Customer Specifi ed BP315.X

Human Sex Hormone Binding Globulin Customer Specifi ed BP316.X

Purifi ed Human Myeloma Antigens

Binding Site myeloma antigens are isolated from human serum and extensively purifi ed by ion exchange chromatography, gel fi ltration and affi nity chromatography. The isotype and light chain type of the myeloma protein is determined by immunoelectrophoresis. These products are supplied in buffer at greater than 95% purity.

Other Human Native Antigens

The purifi ed antigens listed below have been isolated from human material. They are supplied in buffer at variable concentrations.

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New antigens are being added continuously. Please visit www.immunologicals.com or check the new products list at the front of the catalogue.

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NEW Specialist Bulk Antigens

Exclusive to the United States and Canada, Binding Site are pleased to make available a comprehensive portfolio of infectious disease antigens from our ISO certifi ed partners Virion-Serion GmbH.

Material is provided with comprehensive QC test results for ELISA, SDS Page, Western Blot and Densometric Analysis; and is completely deactivated using Affi nity chromatography, UVC-irradiation, ß-propiolactone, and heat inactivation techniques.

PRODUCTDESCRIPTION

CATALOGUE NUMBER

Adenovirus Type 2 Hexon BA128VSAspergillus fumigatus BA132VSBordetella pertussis FHA BA120VS3Bordetella pertussis Toxin PT

BA120VS4

Bordetella pertussis whole-cell antigen

BA120VS8

Borrelia afzelii BA121VSBorrelia garinii BA121GVSBrucella abortus BA116VSCampylobacter jejuni BA139VSCandida albicans BA117VSChlamydia abortus EB+RB BA1373VSERChlamydia pneumoniae (Premium)

BA1371VS

Chlamydia pneumoniae EB+RB

BA1371VSER

Chlamydia trachomatis EB+RB

BA1372VSER

Chlamydia trachomatis MOMP

BA1372VSR2

Coxsackievirus Antigen recombinant

BA134VS01

Coxsackievirus B1 * BA134B1VSCoxsackievirus B5 * BA134B5VSCoxsackievirus B6 * BA134B6VSCytomegalovirus BA109VSEBV capsid Antigen P18 BA1361VSR22EBV capsid Antigen P23 BA1361VSR21Echinococcus granulosus BA107VSEcho Virus Type 6 * BA135VSEcho Virus Type 9 * BA135-9VSEchovirus Antigen recom-binant

BA135VS01

Enterovirus Antigen recom-binant

BA133VS01

Helicobacter pylori BA118VS

Herpes Simplex Virus 1 (HSV-1)

BA1051VS

Herpes Simplex Virus 2 (HSV-2)

BA1052VS

PRODUCTDESCRIPTION

CATALOGUE NUMBER

HSV-1 Glycoprotein G BA1051RVS-GInfl uenza A BA1231VSInfl uenza B BA1232VSLegionella pneumophila BA106VSLeptospira bifl exa BA125VSMeasles Virus BA102VSMeasles Virus (Premium) BA102VS-SMumps Virus BA103VSMycoplasma pneumoniae BA127VSMycoplasma pneumoniae P1

BA127VSP1

Parainfl uenza Virus Type 1 BA1261VSParainfl uenza Virus Type 2 BA1262VSParainfl uenza Virus Type 3 BA1263VSParvovirus NS1 BA122VSNS1Parvovirus Pep A (VP1 unique)

BA122VSVP1A

Parvovirus Pep B (VP2 C-term)

BA122VSVP1B

Parvovirus Pep C (VP1 N-term)

BA122VSVP1C

Parvovirus Pep D (VP1 C-term)

BA122VSVP1D

Parvovirus VP1 BA122VSVP1Parvovirus VP2 BA122VSVP1EParvovirus VP2 VLP BA122VSVP2Respiratory Syncytial Virus (RSV)

BA113VS

Rotavirus BA1193VSRubella Virus BA129G2VSRubella Virus Premium BA129VS-ETBE Virus BA112VSLTBE Virus (Premium) BA112VSToxoplasma gondii BA110VSVaricella Zoster Virus (VZV) BA104VSVaricella Zoster Virus (VZV) Glycoprotein

BA104VSG

Yersinia enterocolitica O:3 BA138VSYersinia enterocolitica O:8 BA13808VSYersinia enterocolitica O:9 BA13809VS

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Clinical Specimens USA / Germany only Clin

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Clinical specimens from human patients are essential, but often overlooked components.

Required for ensuring the validity and integrity of products prior to, and after market introduction, they are also necessary for a host of other critical studies:

• sample interference testing • assay specifi c performance characteristics • normal range determinations • validation studies • regulatory approval and clearance data and documentation

Specimens are available for a multitude of analytes, in a variety of different matrices (e.g. serum, plasma, urine, CSF), all of which can be collected and supplied to include any additional diagnostic information needed.

The integrity of specimens is always kept intact (frozen or refrigerated) and can be packaged to specifi c fi ll-volume requirements as a single source donor, or pooled sample. If necessary, required and requested documentation is completed according to jointly agreed SOPs and provided with each and every collection and shipment, along with our own CERTIFICATE OF TESTING for your records.

To discuss your specifi c requirements contact us on: [email protected] Groups Available

• Autoimmune • Cardiac • Diabetes • Hormones • Infectious Diseases • Metabolic • Special Proteins • Therapeutic Drugs

Please contact us if you do not see the group you require or checkwww.thespecimenbank.com

• Clinical Chemistries • Fertility • Diabetes • Haematology • Immunology • Thyroid • Tumour Markers

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Disease State Sera

Binding Site can provide you with a consistent and reliable source of Disease State Sera products for your needs. All of our offerings are suitable for the production of assay components, such as calibrators and controls. We maintain a large bank of material which cover a wide range of pathological conditions, autoimmune disorders and infectious diseases. Volumes are available in quantities from a milliliter (mL) to liters (L) and can be offered in a variety of formats i.e. serum, plasma or dialyzed serum from single donors.

1mL samples for evaluation are available on request to ensure compatibility with your requirements. Reservations against individual lots can be made while samples are being assessed.

Human Myeloma Disease State Sera


NUMBER

IgG1 Kappa Customer Specifi ed BX020

IgG1 Lambda Customer Specifi ed BX021

IgA1 Kappa Customer Specifi ed BX028

IgA1 Lambda Customer Specifi ed BX029

IgM Kappa Customer Specifi ed BX030

IgM Lambda Customer Specifi ed BX031


NUMBER

Anti-Thyroglobulin Customer Specifi ed BX114

Anti-Thyroid Peroxidase (TPO) Customer Specifi ed BX245


NUMBER

Anti-Glomerular Base Membrane (GBM) Customer Specifi ed BX126

Anti-Mitochondrial Customer Specifi ed BX128

Anti Liver/Kidney Microsomal (LKM) Customer Specifi ed BX129

Human Thyroid Autoantibodies Disease State Sera

Human Liver/Kidney Autoantibodies Disease State Sera


NUMBER

Anti-Striated Muscle Customer Specifi ed BX133

Anti-Smooth Muscle Customer Specifi ed BX134

Human Muscle Autoantibodies Disease State Sera


NUMBER

Anti-Gastric Parietal Cell Customer Specified BX125

Anti-Pancreatic Islet Cell Customer Specified BX131

Anti-Gliadin IgG Customer Specified BX250

Anti-Tissue Transglutaminase (tTG) IgG Customer Specified BX253

Anti-Tissue Transglutaminase (tTG) IgA Customer Specified BX254


NUMBER

Anti-ENA Sm Customer Specified BX100

Anti-ENA RNP Customer Specified BX101

Anti-ENA SSA (Ro) Customer Specified BX102

Anti-ENA SSB (La) Customer Specified BX103

Anti-ENA Jo1 Customer Specified BX104

Anti-ENA Scl-70 Customer Specified BX142


NUMBER

Anti-ANA Homogeneous Customer Specified BX105

Anti-ANA Nucleolar Customer Specified BX106

Anti-Nuclear Coarse Speckled Customer Specified BX108

Anti-dsDNA (Native) Customer Specified BX109

Anti-ANA Fine Speckled Customer Specified BX144

Anti-ANA Speckled Customer Specified BX172

Human Intestinal/Pancreatic Autoantibodies Disease State Sera

Human ENAs (Extractable Nuclear Antigen Antibodies) Disease State Sera

Human ANAs (Anti-Nuclear Antibodies)/dsDNA (Anti-Double-Stranded DNS Antibodies)

Disease State Sera


NUMBER

Anti-ANCA (Mixed) Customer Specified BX179

Anti-Myeloperoxidase (MPO) Customer Specified BX246

Anti-pANCA Customer Specified BX247

Anti-Proteinase III (PR3) Customer Specified BX248

Anti-cANCA Customer Specified BX249

Human ANCAs (Anti-Neutrophil Cytoplasmic Antibodies) Disease State Sera


NUMBER

Anti-Pemphigus (Vulgaris) Customer Specified BX115

Anti-Paraneoplastic Pemphigus Customer Specified BX214

Human Skin Autoantibodies Disease State Sera

Disease S

tate Sera

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NUMBER

Anti-Acetylcholine Receptor Customer Specifi ed BX122

Anti-Hu (ANNA-I) Customer Specifi ed BX199

Anti-Myelin Associated Glycoprotein Customer Specifi ed BX217

Anti-Yo (PCCA-1) Customer Specifi ed BX198


NUMBER

Anti-Cardiolipin IgG Customer Specifi ed BX145

Anti-Cardiolipin IgA Customer Specifi ed BX227

Anti-Cardiolipin IgM Customer Specifi ed BX118

Anti-ß2GP1 IgG Customer Specifi ed BX255

Anti-ß2GP1 IgA Customer Specifi ed BX256

Anti-ß2GP1 IgM Customer Specifi ed BX257

Anti-Phosphatidylserine IgG Customer Specifi ed BX258

Human Neurological Autoantibodies Disease State Sera

Human Phospholipid Antibodies Disease State Sera


NUMBER

Toxoplasma IgG Customer Specifi ed BX210

CMV IgM Customer Specifi ed BX212

EBV IgG Customer Specifi ed BX213

Rabies IgG Customer Specifi ed BX316


NUMBER

Normal Human Plasma/Serum Customer Specifi ed BX050

Polyclonal Human IgG Customer Specifi ed BX055

RF Positive Customer Specifi ed BX110

CRP Positive Customer Specifi ed BX174

ß2 Microglobulin Positive Customer Specifi ed BX175

Positive Pregnancy Plasma Customer Specifi ed BX180

Anti-AB False Positive Customer Specifi ed BX221

Anti-C1Q CIC Customer Specifi ed BX272

Anti-CENP B Customer Specifi ed BX282

Anti-Actin Customer Specifi ed BX290

Non-Characterized Plasmaphoresis Fluid Customer Specifi ed BX291

Infectious Disease/Viral Positive Sera

Additional Disease State Sera

Manufacturing Reagents Man

ufactu

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Reag

ents

If you are a supplier of special protein tests, looking to expand your instrument menu offerings, need an improvement to an existing assay or require a reagent manufacturing partner; Binding Site can supply you with a complete solution.

We can provide IVD manufacturers with products offering the highest degrees of performance, purity, shelf life stability, and lot-to-lot consistency. Additionally, as our reagent manufacturing facility operates to both ISO9001, ISO13485:2003 and GMP quality systems, you can be reassured that your product will be made to the required specifi cations and documented accordingly.

We offer a range of material available as either bulk reagent or as components for use in assays. These can be provided as either standard antibodies, conjugated or latex bound.

NEW • Albumin • α-1-Acid Glycoprotein • α-1-Antitrypsin • Anti-Streptolysin O • ß-2-Microglobulin • Ceruloplasmin • CRP • Cystatin C • Haptoglobin • Immunoglobulin A • Immunoglobulin D • Immunoglobulin G • Immunoglobulin M • Prealbumin • Transferrin

These along with many of our other antibodies can be made available conjugated to a label that suits your technology and into reagents formatted to your needs.

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Human Rheumatoid Factor (RF)/IgG Absorbent

The accurate quantifi cation of human IgM in infectious disease assays may be disrupted by the presence of IgM class Rheumatoid Factor (RF) and by Immunoglobulin G (IgG). Human RF/IgG Absorbent is a reagent designed to remove both IgM class Rheumatoid Factor and IgG from serum prior to the quantifi cation of specifi c IgM.

PRODUCTDESCRIPTION

IgG REMOVAL CAPACITY FORMAT VOLUME CATALOGUE

NUMBERRF / IgG Absorbent 15 mg/mL Whole Serum 1 x 10mL (Non-US) IC050

RF / IgG Absorbent 15 mg/mL Whole Serum Customer Specifi ed IC050.X

visit us for more informationwww.immunologicals.com

June 2015MKG812E

www.immunologicals.com

[email protected]

Head Offi ce:The Binding Site Group Ltd

8 Calthorpe RoadEdgbaston

BirminghamB15 1QT

Tel: 0121 456 9500Fax: 0121 456 9749

[email protected]

Germany, Austria, Switzerland:The Binding Site GmbH

Robert-Bosch-Str. 2A68723 Schwetzingen

GermanyTel: +49 (0)6202 9262-0

Fax: +49 (0)6202 9262-222offi [email protected]

France:The Binding Site France

14 rue des GlairauxCS30026

38522 SAINT EGREVE CEDEXFrance

Tel: +33 (0)4.38.02.19.19Fax: +33 (0)4.38.02.19.20

[email protected]

Spain, Portugal:The Binding Site Spain

Bruc 72 2ª planta, 08009 Barcelona

SpainTel: +34 934676539 Fax: +34 936761666

[email protected]

USA, Canada, Latin America:The Binding Site Inc.

5889 Oberlin Drive, #101 San DiegoCA 92121

United States of AmericaTel: 858 453 9177Fax: 858 453 9189

Toll Free: 800 633 [email protected]

Czech Republic, Slovak Republic:The Binding Site s.r.o.

Sinkulova 55, 147 00 Prague 4, Czech Republic

Tel: +420 223 013 988-9 Fax: +420 222 948 482

[email protected]

Belgium, Netherlands, Luxembourg:The Binding Site SPRL/BVBA

Dendermondestraat 442018 Antwerpen,

BelgiumTel: +32 (0)3 242 88 21Fax: +32 (0)3 242 88 20

[email protected]

Italy:The Binding Site Italy

Via Zanica 1924050 Grassobbio (BG)

ItalyTel: +39 035 0951500Fax: +39 035 0951501

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product catalogue...immunodiagnostic assays for the global laboratory market. with extensive...

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