Upload File

prostate cancer · how common is prostate cancer? •most common cancer in male in uk. •40,000...

  • Home
  • Documents
  • PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate
34
People Centred Positive Compassion Excellence PROSTATE CANCER Mr. Jawad Islam MBBS, MSc, FRCS(Ed), FEBU, FRCS(Urology) Consultant Urologist

Upload: others

Post on 23-May-2020

2 views

Category:

Documents


0 download

Report

TRANSCRIPT

Page 1: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

PROSTATE CANCER

Mr. Jawad Islam MBBS, MSc, FRCS(Ed), FEBU, FRCS(Urology)

Consultant Urologist

Page 2: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

• Where is prostate located and what is its function?

• What is prostate cancer?

• How common is prostate cancer?

• What causes it?

• What are the risk factors?

• Can it be prevented?

• Tests to find early prostate cancer?

• How you stage prostate cancer?

• What treatments are available?

Page 3: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

Prostatecanceruk.org

Page 4: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

Page 5: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

Function & problems of prostate

• It produces fluid which forms the part of

semen.

• THREE main problems

Benign prostate hyperplasia

Prostatitis

Prostate cancer

Page 6: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

What is prostate cancer?

• Every cell is dividing in an orderly fashion

and in a controlled manner.

• When cell division becomes uncontrolled

abnormal cells are produced - cancer cells

“GROWTH OF ABNORMAL CELLS”

Prostate cancer

• Cancer cells invade & damage normal

tissue

Page 7: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

How common is prostate cancer?

• Most common cancer in male in UK.

• 40,000 new cases diagnosed every year

(110 cases/day)

• 250,000 men living with prostate cancer.

• Worldwide, 1.11 million cases diagnosed in 2012.

• Lifetime risk: 1 in 8

Prostatecanceruk.org, cancerresearchuk.org

Page 8: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

How many die from Prostate

cancer?

• Second most common cause of death after lung cancer.

• 10,800 men died in 2012 (30 every day)

• 1970 ---- 4 in 10 survived beyond 5 years

• 2012 ---- 8 in 10 Survived beyond 5 years

cancerresearchuk.org

Page 9: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

What causes prostate cancer?

AGE

RISK FACTORS

Page 10: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

cancerresearchuk.org

Page 11: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

RISK FACTORS

• Family History

Father, brother ---- 2 to 3 times

Diagnosed <60 years --- 3 to 4 times

Mother with Breast cancer

BRCA2 gene ---- 5 to 7 times

Inheritance of Faulty gene

cancerresearchuk.org

Page 12: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

RISK FACTORS

• Black African ----- 2 to 3 times

• Obesity

• High calcium diet

• vasectomy

Page 13: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

SCREENING OF PROSTATE

CANCER “Finding the disease when there are no s/s”.

• Screening finds the cancers in early stage

• Prostate cancer screening

PSA (prostate specific antigen)

DRE (digital rectal examination)

Page 14: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

PSA • Made in prostate cells

• Measured with Blood test

• Normal Value <4ng/ml (Age dependent)

• PSA can be increased in:

Prostate cancer

Prostatitis / UTI

Benign Enlargement of prostate

• Prostate specific but not cancer specific

Page 15: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

DIGITAL RECTAL EXAMINATION

• Lubricated gloved finger

• Hardness, lump or bumps of prostate

Page 16: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

PROSTATE CANCER SCREENING

• PSA is prostate specific, not cancer

specific.

• PSA senstivity 80%, Specificity 40%

• DRE ---- not very accurate

Page 17: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

PROSTATE CANCER SCREENING

• Many big trials (European, PLCO)

• Tests are not accurate

• Does not reduce mortality

Hence not recommended in UK

Page 18: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

PROSTATE BIOPSY

Page 19: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

DIAGNOSIS

Prostate Biopsy

ADENOCARCINOMA PROSTATE

GLEASON SCORE

Low Grade 2 to 6

Moderate Grade 7

Severe Grade 8 to 10

Page 20: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

STAGING OF PROSTATE CANCER

• Localized

• Locally Advance

• Metastatic

Page 21: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

MRI PROSTATE

Page 22: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

BONE SCAN

Page 23: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

TREATMENT OPTIONS

1. ACTIVE SURVILLANCE

2. SURGERY

3. RADIOTHERAPY

4. HORMONAL TREATMENT

Page 24: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

ACTIVE SURVILLANCE

• Localised cancer

• Low grade

• Small volume

• Monitor PSA

• Repeat prostate biopsy in 1 year

• Treatment if disease gets worse

Page 25: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

SURGERY

RADICAL PROSTATECTOMY

• Localised prostate

cancer

• Low or moderate

grade

• Any volume

Page 26: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

ROBOTIC RADICAL PROSTATECTOMY

Page 27: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

LAPROSCOPIC RADICAL PROSTATECTOMY

Page 28: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

RADIOTHERAPY

• Locally advance

cancer

• Moderate to high

grade

• Any volume

Page 29: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

BRACHYTHERAPY

• Localised cancer

• Low to moderate

grade

• Low Volume

Page 30: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

HORMONE TREATMENT

INJECTIONS

• Metastatic cancer

• Cuts of Testosterone

• Usually given 3 monthly

• Not curative

Page 31: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

CHEMOTHERAPY

• Metastatic disease not controlled with

hormonal treatment.

• Fit patients

• Palliative care

Page 32: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

PROSTATE CANCER

Blackpool Victoria Hospital

2014

• Newly Diagnosed cases 173

• Ref. Routes (Fast track, consults, A&E)

• TREATMENT

26 Patients Active Monitoring (BVH)

122 Hormone Therapy (BVH)

20 Radical Prostatectomy (Lanc Teaching Hospital)

2 Radiotherapy (Lancashire Teaching Hospitals)

3 Surgery (The Christie)

Page 33: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

THANK YOU

Page 34: PROSTATE CANCER · How common is prostate cancer? •Most common cancer in male in UK. •40,000 new cases diagnosed every year (110 cases/day) •250,000 men living with prostate

People Centred

Positive

Compassion

Excellence

Next Members Seminar

Depression Awareness Week

Wednesday, 15th April 2015

10 – 11 am

Lecture Theatre, Education Centre,

BVH.


Prostate Cancer

PROSTATE CANCER is the most common cancer in men, with 233,000 new … · 2020-01-22 · Doctor to DOCTOr PROSTATE CANCER is the most common cancer in men, with 233,000 new cases

Prostate Cancer · detecting prostate cancer PSA, Free PSA, proPSA (or PSA2) Differentiate prostate cancer from benign prostate conditions that elevate PSA decrease unecessary prostate

TREATING PROSTATE CANCER · 2018-11-22 · Prostate cancer can, in some advanced cases, cause urinary difficulties similar to those for BPH. So some men with prostate cancer may be

Molecular analysis of multifocal prostate cancer cases

The Prostate Revolution - Greater Manchester Cancer...Prostate Cancer is the most common male cancer 48,000 new cases each year Lung cancer 25,000 new cases Bowel cancer 23,000 new

PROSTATE CANCER - 2012 241,740 new cases 29 % of all new male cancer cases 28,170 deaths Lifetime risk of prostate cancer 1:5

Collecting Cancer Data: Prostate · Collecting Cancer Data: Prostate 6/11/09 2008-2009 NAACCR Webinar Series 2 Prostate Cancer • Prostate cancer is most common non-skin cancer in

PROSTATE CANCER PATIENT GUIDE · 2018-01-23 · IS THERE A CURE FOR PROSTATE CANCER? ... to all incurable prostate cancer. Prostate cancer is 100% ... PROSTATE CANCER PATIENT GUIDE

Romney Prostate Cancer - cdn.ymaws.com · • Most cases of prostate cancer have a good prognosis, even without treatment, but some are aggressive; the lifetime risk of dying of prostate

Prostate Cancer Hospitals India | Prostate Cancer Surgeon in India

Prostate Cancer Screening. Google Search “Prostate Cancer” “Google Health” prostate cancer (OK) “Should All Men Be Screened for Prostate Cancer?” ABC

Prostate Cancer Screening - cancercentrum · Prostate Cancer Screening Jonas Hugosson Professor . Avd för Urologi, Sahlgrenska Akademin, ... also non over-diagnosed cases will have

Prostate-Specific Antigen (PSA) Screening for Prostate Cancer€¦ · Prostate cancer is the second leading cause of cancer death in men, exceeded by lung cancer. Prostate cancer

New Developments in Prostate Cancer Final - Handout.ppt - New Developments in Prostate Cancer Final - 2.pdfNew Developments in Prostate Cancer: Localized Prostate CancerLocalized Prostate

PET/CT PROSTATE CANCER: CASES - Nucleus filePET/CT PROSTATE CANCER: CASES Stefano Fanti . CASE 1 . 69 years-old patient treated in June 2011 with ... 0,86 ng/mL in January 2013 (PSAdt

Prostate Cancer Research Program - CDMRP · toward new advancements for patients • Impact: ... for prostate cancer patients, in some cases in the near future • New Investigators:

Prostate Needle Biopsy: The Pitfalls and the Role of the Pathologist – Patient Track Prostate Cancer Symposium “Intriguing Cases / Emerging Strategies

Intact Prostate Contouring Guideecontour.org/training/intact_prostate_module.pdf · Not all cases of intact prostate cancer are created equal! GU à Prostate à intact (not post-prostatectomy)

National Prostate Cancer Audit - Executive Summary Annual ......Prostate cancer is the most frequently diagnosed solid cancer (over 40,000 new cases each year) and the second most

Management of prostate cancer in Latin America€¦ · 15% compared to breast cancer x 1.14 breast cancer cases AWARNESS Prostate cancer is a neglected disease Instituto Nacional

Rétrospective et perspectives Cancer de la prostate · 2020-02-20 · Cancer de prostate localisé Cancer prostate M0 hormono-résistant Cancer prostate métastatique hormono -naif

Prostate cancer screening and the - BMJ Prostate cancer is an important health problem. More than 40 000 incident cases of prostate cancer and more than 10 000 prostate cancer related

Prostate Cancer Screening - OSU Center for Continuing ... on Prostate Cancer Screening - 2.pdf · prostate-specific antigen-based screening. ... Goteborg Randomized Prostate Cancer

PROSTATE CANCER PROSTATE CANCER What you should know about Prostate Cancer: Prostate cancer is the most common type of cancer found in American men,

Cancer Prostate

Benign Prostate Hyperplasia & Prostate Cancer

PET/CT in Prostate Cancer - Human Health Campus€¦ · PET/CT in Prostate Cancer . Prostate Cancer In Europe 2.6 million prostate cancer cases are diagnosed each year, with a mortality

Prostate Cancer - 2010 Report on Cancer Statistics in ... · prostate cancer cases that would have occurred each year if prostate cancer incidence rates alone had changed but the

Prostate cancer treatment with irreversible electroporation€¦ · Stehling et al.: Global Congress on Prostate Cancer: 05 – 07.02.2015 5 In all cases MRIs were obtained before

Immunohistochemistry in Prostate Pathology Revie immun -prostate-pathology.pdf · IHC Prostate Pathology 4 Prostate Cancer Prostate cancer is the second most common cancer in men

Prostate Prostate Cancer Cancer Overview and Recent ... · PDF fileProstate Prostate Cancer Cancer Overview and Recent Advances: ... Prostate Cancer Overview and Recent Advances:

ASIAN FOCUS Prostate cancer in Asia: A collaborative reporthub.hku.hk/bitstream/10722/221571/1/content.pdf1. Introduction Approximately 238,590 new cases of prostate cancer (PCa) were

Prostate Cancer and BPH Management Revolutionisednuadamedical.com/wp-content/uploads/2016/02/nuada-prostate-cancer...Prostate Cancer and BPH Management Revolutionised. 2 Prostate cancer