Critical Advantage to Healthy Aging &

Performance:

Benevia’s Superior Protein Source

2

Protein Energy is the Most Important Nutrient in Aging &

Performance.

•With inadequate or inefficient protein intake, muscle loss is accelerated and muscle strength and function decrease (J.Gerontol Med Sci 2002; 11:698)

•Muscle Loss naturally begins around the age of 30 and continues into our 60’s at a rate of 1 to 2% of loss each year and accelerates after 60 to as high as 3 to 5% loss annually. (J.Am. Ger. Soc 2003. 51: 1120-1124)

•Even healthy, physically active subjects lose muscle at ~1–2% per year after age 50. This means that by the time we reach 80, we may have lost up to 50% of muscle vs when we were 30. (Clin Nutr 2007; 26: 389-399)

•Whereas Osteoporosis is considered a disease of bone loss for women. Muscle loss is a critical ‘disease’ of aging that effect men and women equally (J. Lab Clin Med 2001; 137: 231-243)

Loss of Muscle Mass : #1 Factor that complicates our ability to

Stay Healthy

40

50

60

70

80

90

100

110

35-39 40-44 45-49 50-54 55-59 60-64

Men

Women

Percent loss of Strength & Energy seen in aging

•The aging shift of more Fat Mass vs

Muscle, increases the level of Inflammation

in our Bodies which is the underlying issue

to why over 60% of people age 60 and over

have at least one chronic health issue to

manage. This is also why bone & joint

movement becomes more strained

(J.Am.Ger.Soc 2002; 50:889-896)

•By the time we are 60yrs our ability to

maintain strength and ease of movement

decreases by over 50% (J.Am.Ger.Soc

2004; 52:80-85)

Muscle Mass decreases result in over a 100% increase in fat

Mass by the time we reach 70yrs vs when we were 25yrs old.

Loss of Muscle Mass : #1 Factor that complicates

our ability to Stay Healthy

5

Stresses of Aging require Higher Protein

Amounts and Better sources of Protein

Muscle loss as we age is a bigger problem

than osteoporsis (i.e., bone loss). 80% of

men and women 50 to 80 years experience

moderate to severe muscle loss while 40%

of women experience bone loss.

40% of individuals 50 & older do not

consume the minimally recommended

amount of protein and 100% of consumers

require higher total amounts of protein

(Am.J.Clin.Nutr 1989; 50:1231-1233)

Stresses of Aging require Higher Protein

Amounts and Better sources of Protein

Not all Protein Sources have the same ability to build muscle mass and

strength. To overcome the resistance of aging, more potent forms of

protein is required that can help grow muscle mass and strength. (Exp

Geront. 2006; 41:215-219)

By 40 must include high levels of certain amino acids able to overcome the

resistance muscles have as we age. This must include high levels of

essential amino acids and especially one called Leucine Am.J.Physiol

2006; 291:381

Not All Proteins are Corrected Equally.

The Most Effective Protein Energy Source must Include specific

combinations of essential amino acids including Leucine.

15 years of clinical research by leading scientists at the Reynolds Institute on

Aging at the University of Arkansas for Medical Services and the USDA

Center on Aging at Tufts University confirm these scientific facts

0

10

20

30

40

50

60

70

80

90

100

Soy Casein Whey ViaLeuPro

Percent Change in Muscle Building by

selected sources or blends of protein

To improve muscle building,

specialized sources of protein with

high levels of Leucine are Required

(Am.J.Clin Nutr. 2006; 84:475-482)

Specialized Leucine Protein Blends

are 4x more effective at

overcoming the resistance of aging

and building muscle faster.

Exp.Geront. 2006;41:215-219)

High Levels of Leucine with

Essential Amino Acids Overcome

the muscles resistance to aging

and help build stronger and more

energetic muscle for active living0

5

10

15

20

25

30

35

mg

Ph

e /

leg

Muscle Building Capacity in Young vs Elderly with low vs

high levels of Leucine and essential amino acid intake

<25 yr old > 40 yr old

Low Leu Hi Leu Low Leu Hi Leu

8

High Leucine Protein Blends and Increased Total Protein Intake

Help Muscle overcome the resistance to Aging.

3 year observation results of subjects consuming 5

different levels of protein daily, ranging from below RDA

amount to slightly higher than RDA levels of intake.

Those with higher protein intake (Quintile 5) show

smallest amount of muscl e loss (AGS 2010 Seminar)

Eight to 16 weeks of supplementation with High

Leucine Protein Blend results in Significant

improvement in Muscle Functional tests of distance

and time. On average a 20% improvement is seen

with improved protein intake in 8 weeks of consumption

of Benevia with ViaLeuPro (Am.J.Clin Nutr 2003;

78:250)

Specialized Protein Blends with High Leucine prevent and reduce the

loss of lean muscle mass seen with aging and help build muscle

energy and strength better than other protein sources available in food

or nutritional supplements and replacements.

Results of Supplementation are seen in 4 to 8 weeks and longer

Summary Highlights on the

Use of Superior Protein Sources

• Muscle Loss in aging is a major risk to health and active lifestyles and effects more

people in the aging process than does osteoporosis,

• Increased protein intake from age 40 yrs is recommended to help avoid the loss of

muscle mass and the resulting increase in fat mass seen after 50yrs of age,

• Not all protein sources and types are equal in building muscle during aging,

• Resistance of muscle to grow and become stronger in aging increases the loss of

muscle and energy. However, superior protein sources with high levels of Leucine and

other essential amino acids can overcome this age-related resistance,

• 4 to 8 weeks of supplementation of these superior protein blends will result in

significant improvement and regain of muscle mass, strength & energy and function,

• Consumers of high intake of protein with Leucine and Essential Amino Acids have

greater muscle mass, less bone loss and are able to maintain higher levels of active

lifestyles and function – all associated with lower risks of disease

Six Critical Scientific Studies and Peer Reviewed Publications

Support The Need and Benefit of Superior Protein Sources

with Leucine & Essential Amino Acids

Study Type Findings Product Position Competitive Difference

Role of Amino Acids in stimulation of protein synthesis

Human experimental 15-18g EAA as effective as 40g intact protein

Proprietary blend and volume control

Smaller volume with greater effect; non-milk

Response to 16wk supplement of EAA

Human Control Significant gains in functional performance

Effective and convenient use of blend

Specific outcome improvements

Effect of Age on Response to 7g EAA

Human Experimental Controls

Specific needs and response of aged vs youth

Age Specific Benefit and Effect

Specialized blends for target consumer

Comparisons of EAA’s & Leucine vs other proteins and products

Human experimental Dose and combination use

Optimal availability Superior stimulation of protein synthesis

Relationship of Protein Metabolism and Inflammatory Control

In Vivo and Human experimental

Omega-3 effect on inflammation and protein metabolism

Control of inflammation

Protein and Inflammatory control as synergistic benefit

Bed rest with EAA supplementation

Human Control Supplementation ameliorates effect of bed rest

Effective supplementation stops muscle loss

Specific Outcome improvements

Reference List and publications available at ‘www.gobenevia.com’

Contact BeneVia/HealthSpan Instituteweb: www.GoBeneVia.com

facebook: http://www.facebook.com/GoBeneVia

email: info@the-healthspan.com

phone: 1-888-855-4442

HealthSpan Solutions, LLC

2228 Cottondale Lane, Suite 100

Little Rock, AR 72205